IMP: Integrative Multi-species Prediction

Drosophila melanogaster

37 known processes

tomosyn (Dmel_CG17762)

CG17762 gene product from transcript CG17762-RB

(Aliases: CG2205,BcDNA:RH19475,CG11056,Dmel\CG17762,Tomosyn,CG17762)

FLYBASE: FBgn0030412
Entrez: 32217
UniProtKB: Q9VYK6
UniProtKB: Q9VYK5
UniProtKB: A4V4D2

Process Predictions
Disease Predictions

tomosyn biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
learning or memory	GO:0007611	141	0.983
cognition	GO:0050890	141	0.930
olfactory learning	GO:0008355	56	0.899
neurological system process	GO:0050877	358	0.886
olfactory behavior	GO:0042048	97	0.871
synaptic transmission	GO:0007268	288	0.867
neuromuscular junction development	GO:0007528	149	0.833
synapse organization	GO:0050808	196	0.767
neuromuscular synaptic transmission	GO:0007274	67	0.729
associative learning	GO:0008306	65	0.728
single organism behavior	GO:0044708	391	0.709
memory	GO:0007613	94	0.662
regulation of nervous system development	GO:0051960	248	0.599	Fly
secretion by cell	GO:0032940	101	0.559	Mouse
long term memory	GO:0007616	62	0.548
chemosensory behavior	GO:0007635	106	0.461
regulation of localization	GO:0032879	275	0.439	Mouse
muscle structure development	GO:0061061	224	0.433
developmental growth	GO:0048589	280	0.384
regulation of cellular component biogenesis	GO:0044087	201	0.383
learning	GO:0007612	75	0.377
imaginal disc derived appendage development	GO:0048737	399	0.363
chromatin remodeling	GO:0006338	72	0.329
inter male aggressive behavior	GO:0002121	60	0.325
regulation of cell projection organization	GO:0031344	92	0.236
medium term memory	GO:0072375	8	0.234
response to abiotic stimulus	GO:0009628	341	0.211
response to light stimulus	GO:0009416	124	0.195
regulation of growth	GO:0040008	233	0.184	Fly
striated muscle cell differentiation	GO:0051146	90	0.160
chromatin organization	GO:0006325	207	0.157
positive regulation of molecular function	GO:0044093	136	0.156
imaginal disc derived wing morphogenesis	GO:0007476	337	0.154
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.152
response to oxygen containing compound	GO:1901700	200	0.146	Fly
regulation of neurotransmitter levels	GO:0001505	38	0.131
regulation of cellular localization	GO:0060341	136	0.126	Mouse
positive regulation of cell motility	GO:2000147	3	0.126
axonogenesis	GO:0007409	290	0.124
signal release	GO:0023061	49	0.122	Mouse
calcium ion transport	GO:0006816	24	0.122
biological adhesion	GO:0022610	138	0.116
vesicle mediated transport	GO:0016192	381	0.112	Mouse
regulation of synapse organization	GO:0050807	110	0.110
cellular macromolecular complex assembly	GO:0034622	153	0.108
regulation of gene expression epigenetic	GO:0040029	128	0.108
positive regulation of cell migration	GO:0030335	2	0.106
cellular response to abiotic stimulus	GO:0071214	58	0.104
synaptic growth at neuromuscular junction	GO:0051124	119	0.102
peptidyl amino acid modification	GO:0018193	105	0.101
protein modification process	GO:0036211	438	0.101	Fly
intracellular signal transduction	GO:0035556	300	0.096
protein complex biogenesis	GO:0070271	201	0.093
regulation of synaptic transmission	GO:0050804	69	0.092
appendage morphogenesis	GO:0035107	397	0.088
cell adhesion	GO:0007155	136	0.087
aromatic compound catabolic process	GO:0019439	166	0.086
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.084
chemical homeostasis	GO:0048878	92	0.084	Mouse
cellular response to oxygen containing compound	GO:1901701	79	0.083
cellular response to dna damage stimulus	GO:0006974	223	0.083
regulation of anatomical structure morphogenesis	GO:0022603	242	0.082
synapse assembly	GO:0007416	143	0.079
regulation of cellular catabolic process	GO:0031329	157	0.078
erbb signaling pathway	GO:0038127	58	0.073
behavioral response to ethanol	GO:0048149	49	0.073
regulation of molecular function	GO:0065009	217	0.073	Fly
growth	GO:0040007	359	0.072	Fly
establishment of localization in cell	GO:0051649	402	0.071	Mouse
circadian behavior	GO:0048512	76	0.071
wing disc morphogenesis	GO:0007472	344	0.071
post embryonic appendage morphogenesis	GO:0035120	385	0.070
small molecule metabolic process	GO:0044281	305	0.070
axon development	GO:0061564	297	0.070
actin filament based process	GO:0030029	220	0.069	Fly
eye morphogenesis	GO:0048592	260	0.069
organic substance transport	GO:0071702	257	0.069	Mouse
actin polymerization or depolymerization	GO:0008154	31	0.069
regulation of catabolic process	GO:0009894	170	0.068
muscle contraction	GO:0006936	13	0.068
regulation of cell differentiation	GO:0045595	302	0.068	Fly
regulation of neuron differentiation	GO:0045664	103	0.067
regulation of cell development	GO:0060284	215	0.066	Fly
response to radiation	GO:0009314	155	0.066
negative regulation of developmental process	GO:0051093	201	0.065	Fly
positive regulation of phosphate metabolic process	GO:0045937	139	0.065
axon guidance	GO:0007411	233	0.064
appendage development	GO:0048736	401	0.063
regulation of synapse structure and activity	GO:0050803	128	0.063
organophosphate metabolic process	GO:0019637	195	0.063
phosphorylation	GO:0016310	294	0.063	Fly
regulation of phosphate metabolic process	GO:0019220	210	0.062	Fly
cation homeostasis	GO:0055080	51	0.061
positive regulation of cellular component biogenesis	GO:0044089	80	0.061
stem cell proliferation	GO:0072089	88	0.060	Fly
regulation of cellular component size	GO:0032535	98	0.060
regulation of neuron projection development	GO:0010975	69	0.060
ras protein signal transduction	GO:0007265	88	0.059
endocytosis	GO:0006897	310	0.057
mrna metabolic process	GO:0016071	124	0.057
heterocycle catabolic process	GO:0046700	166	0.057
response to organic substance	GO:0010033	284	0.056	Fly
cellular response to organic substance	GO:0071310	132	0.055	Fly
regulation of phosphorus metabolic process	GO:0051174	210	0.054	Fly
locomotory behavior	GO:0007626	176	0.054
epidermal growth factor receptor signaling pathway	GO:0007173	58	0.053
negative regulation of multicellular organismal process	GO:0051241	142	0.053	Fly
response to alcohol	GO:0097305	95	0.053	Fly
single organism biosynthetic process	GO:0044711	206	0.053
muscle organ development	GO:0007517	127	0.052
cellular protein modification process	GO:0006464	438	0.052	Fly
organic substance catabolic process	GO:1901575	308	0.051
cation transport	GO:0006812	110	0.049
secretion	GO:0046903	109	0.049	Mouse
regulation of synaptic growth at neuromuscular junction	GO:0008582	89	0.048
regulation of cell death	GO:0010941	173	0.048	Fly
regulation of neuron death	GO:1901214	26	0.047
detection of stimulus	GO:0051606	156	0.047
neurotransmitter transport	GO:0006836	37	0.046
regulation of catalytic activity	GO:0050790	185	0.046	Fly
regulation of carbohydrate metabolic process	GO:0006109	10	0.046
regulation of transport	GO:0051049	181	0.045	Mouse
cell division	GO:0051301	248	0.045	Fly
synaptic vesicle localization	GO:0097479	53	0.045
short term memory	GO:0007614	19	0.045
positive regulation of catabolic process	GO:0009896	105	0.044
organelle localization	GO:0051640	148	0.044
cyclic nucleotide metabolic process	GO:0009187	28	0.044
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.044
regulation of protein metabolic process	GO:0051246	256	0.043	Fly
regulation of cell morphogenesis	GO:0022604	163	0.043
macromolecular complex assembly	GO:0065003	256	0.043
cation transmembrane transport	GO:0098655	88	0.043
single organism catabolic process	GO:0044712	228	0.043
neural precursor cell proliferation	GO:0061351	75	0.042	Fly
taxis	GO:0042330	304	0.042
sensory perception	GO:0007600	196	0.042
actin filament polymerization	GO:0030041	27	0.042
urogenital system development	GO:0001655	72	0.040
cell migration	GO:0016477	238	0.039
establishment of protein localization	GO:0045184	163	0.039	Mouse Fly
muscle system process	GO:0003012	21	0.039
regulation of receptor activity	GO:0010469	10	0.039
inorganic ion transmembrane transport	GO:0098660	73	0.039
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.039
regulation of erbb signaling pathway	GO:1901184	42	0.039
cellular catabolic process	GO:0044248	372	0.038
nucleobase containing small molecule metabolic process	GO:0055086	174	0.038
phagocytosis	GO:0006909	215	0.037
regulation of hydrolase activity	GO:0051336	97	0.037
positive regulation of rna biosynthetic process	GO:1902680	266	0.037
regulation of protein complex assembly	GO:0043254	42	0.037
positive regulation of cell communication	GO:0010647	250	0.037
positive regulation of protein metabolic process	GO:0051247	128	0.037
nucleobase containing compound catabolic process	GO:0034655	165	0.036
purine containing compound biosynthetic process	GO:0072522	30	0.036
negative regulation of rna biosynthetic process	GO:1902679	240	0.036
chemotaxis	GO:0006935	249	0.036
eye photoreceptor cell development	GO:0042462	81	0.036
homeostatic process	GO:0042592	199	0.035	Mouse
cell cell adhesion via plasma membrane adhesion molecules	GO:0098742	26	0.034
photoreceptor cell development	GO:0042461	96	0.034
regulation of nucleoside metabolic process	GO:0009118	50	0.034
carbohydrate derivative metabolic process	GO:1901135	217	0.034
nucleoside phosphate biosynthetic process	GO:1901293	34	0.033
purine ribonucleotide metabolic process	GO:0009150	145	0.033
positive regulation of phosphorus metabolic process	GO:0010562	139	0.033
eye development	GO:0001654	323	0.032
positive regulation of signaling	GO:0023056	243	0.032
regulation of multicellular organismal development	GO:2000026	414	0.032	Fly
actin cytoskeleton organization	GO:0030036	206	0.032	Fly
striated muscle contraction	GO:0006941	5	0.032
renal system development	GO:0072001	72	0.032
regulation of developmental growth	GO:0048638	174	0.031
protein phosphorylation	GO:0006468	169	0.031	Fly
cell death	GO:0008219	279	0.031	Fly
cellular protein complex assembly	GO:0043623	71	0.031
positive regulation of reactive oxygen species metabolic process	GO:2000379	0	0.031
regulation of cellular ketone metabolic process	GO:0010565	3	0.030
gliogenesis	GO:0042063	80	0.030
mapk cascade	GO:0000165	107	0.030
chromatin modification	GO:0016568	147	0.030
positive regulation of catalytic activity	GO:0043085	118	0.030
regulation of metal ion transport	GO:0010959	15	0.030
protein transport	GO:0015031	155	0.029	Mouse
regulation of cellular amino acid metabolic process	GO:0006521	0	0.029
exocytosis	GO:0006887	28	0.029	Mouse
skeletal muscle tissue development	GO:0007519	13	0.029
signal transduction by phosphorylation	GO:0023014	107	0.029
response to ethanol	GO:0045471	59	0.029
dendrite development	GO:0016358	204	0.028
positive regulation of gtpase activity	GO:0043547	43	0.028
regulation of gene silencing	GO:0060968	63	0.028
purine nucleotide metabolic process	GO:0006163	146	0.028
epithelial cell migration	GO:0010631	148	0.028
regulation of epithelial cell proliferation	GO:0050678	4	0.027
negative regulation of nervous system development	GO:0051961	92	0.027	Fly
response to starvation	GO:0042594	97	0.027
positive regulation of biosynthetic process	GO:0009891	316	0.027
regulation of epithelial cell migration	GO:0010632	12	0.027
regulation of protein localization	GO:0032880	76	0.027	Mouse
eye photoreceptor cell differentiation	GO:0001754	145	0.027
regulation of cellular protein metabolic process	GO:0032268	243	0.027	Fly
heart process	GO:0003015	37	0.026
metal ion transport	GO:0030001	74	0.026
single organism carbohydrate metabolic process	GO:0044723	72	0.026
compound eye development	GO:0048749	307	0.026
phosphatidylinositol 3 kinase signaling	GO:0014065	4	0.026
lateral inhibition	GO:0046331	206	0.026
torc1 signaling	GO:0038202	12	0.025
regulation of system process	GO:0044057	36	0.025
regulation of stem cell proliferation	GO:0072091	40	0.024	Fly
meiotic cell cycle process	GO:1903046	132	0.024
flight behavior	GO:0007629	26	0.024
regulation of protein modification process	GO:0031399	112	0.024	Fly
response to lipopolysaccharide	GO:0032496	4	0.024
regulation of phosphorylation	GO:0042325	147	0.024	Fly
positive regulation of transport	GO:0051050	92	0.024	Mouse
response to external biotic stimulus	GO:0043207	293	0.024
maintenance of location	GO:0051235	73	0.024
dephosphorylation	GO:0016311	51	0.024
metal ion homeostasis	GO:0055065	44	0.024
reactive oxygen species metabolic process	GO:0072593	22	0.023
regulation of cellular amine metabolic process	GO:0033238	3	0.023
protein dna complex subunit organization	GO:0071824	86	0.023
positive regulation of cellular protein metabolic process	GO:0032270	118	0.023
regulation of ras protein signal transduction	GO:0046578	93	0.023
response to decreased oxygen levels	GO:0036293	58	0.023
tissue migration	GO:0090130	155	0.023
cell maturation	GO:0048469	144	0.023	Fly
nucleotide metabolic process	GO:0009117	161	0.023
compound eye photoreceptor cell differentiation	GO:0001751	140	0.023
nucleoside phosphate metabolic process	GO:0006753	162	0.023
negative regulation of cellular component organization	GO:0051129	108	0.023
skeletal muscle organ development	GO:0060538	48	0.023
regulation of actin polymerization or depolymerization	GO:0008064	27	0.023
neurotransmitter secretion	GO:0007269	35	0.023
cell projection assembly	GO:0030031	94	0.023
positive regulation of cellular component organization	GO:0051130	156	0.023
catabolic process	GO:0009056	409	0.023
regulation of response to external stimulus	GO:0032101	115	0.022	Human
ribonucleotide metabolic process	GO:0009259	145	0.022
cellular response to chemical stimulus	GO:0070887	199	0.022	Fly
positive regulation of nervous system development	GO:0051962	69	0.022
regulation of synaptic plasticity	GO:0048167	14	0.022
negative regulation of gene expression	GO:0010629	387	0.022
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.022
brain development	GO:0007420	120	0.022
regulation of gtpase activity	GO:0043087	44	0.022
positive regulation of developmental process	GO:0051094	143	0.022
cell proliferation	GO:0008283	299	0.021	Fly
photoreceptor cell differentiation	GO:0046530	170	0.021
purine containing compound metabolic process	GO:0072521	155	0.021
ribose phosphate metabolic process	GO:0019693	145	0.021
positive regulation of purine nucleotide metabolic process	GO:1900544	55	0.021
negative regulation of biosynthetic process	GO:0009890	277	0.021
regulation of organelle organization	GO:0033043	196	0.021
central nervous system development	GO:0007417	201	0.021
small gtpase mediated signal transduction	GO:0007264	88	0.021
regulation of protein modification by small protein conjugation or removal	GO:1903320	25	0.021
positive regulation of developmental growth	GO:0048639	62	0.020
regulation of cellular component movement	GO:0051270	42	0.020
organonitrogen compound biosynthetic process	GO:1901566	117	0.020
regulation of actin cytoskeleton organization	GO:0032956	42	0.020
glycosyl compound metabolic process	GO:1901657	127	0.020
regulation of cell shape	GO:0008360	113	0.020
cellular response to molecule of bacterial origin	GO:0071219	3	0.020
visual learning	GO:0008542	4	0.020
inositol lipid mediated signaling	GO:0048017	4	0.019
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.019
meiotic nuclear division	GO:0007126	151	0.019
muscle cell differentiation	GO:0042692	103	0.019
peptidyl lysine modification	GO:0018205	57	0.019
neuron death	GO:0070997	27	0.019
rho protein signal transduction	GO:0007266	14	0.019
regulation of behavior	GO:0050795	75	0.019
cellular response to biotic stimulus	GO:0071216	4	0.019
cellular response to lipopolysaccharide	GO:0071222	3	0.019
positive regulation of response to external stimulus	GO:0032103	44	0.019
renal tubule morphogenesis	GO:0061333	44	0.019
positive regulation of purine nucleotide catabolic process	GO:0033123	46	0.019
inorganic cation transmembrane transport	GO:0098662	61	0.019
histone modification	GO:0016570	106	0.019
positive regulation of ras gtpase activity	GO:0032320	36	0.019
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.019
organic cyclic compound catabolic process	GO:1901361	168	0.018
regulation of cell division	GO:0051302	72	0.018
regulation of neurogenesis	GO:0050767	158	0.018	Fly
lamellipodium organization	GO:0097581	21	0.018
regulation of epidermal growth factor receptor signaling pathway	GO:0042058	42	0.018
camp metabolic process	GO:0046058	19	0.018
cellular nitrogen compound catabolic process	GO:0044270	165	0.018
rna catabolic process	GO:0006401	37	0.018
regulation of cell proliferation	GO:0042127	163	0.018	Fly
developmental cell growth	GO:0048588	52	0.017
meiotic cell cycle	GO:0051321	171	0.017
sensory organ morphogenesis	GO:0090596	260	0.017
social behavior	GO:0035176	4	0.017
regulation of reactive oxygen species metabolic process	GO:2000377	8	0.017
guanosine containing compound catabolic process	GO:1901069	74	0.017
purine nucleotide catabolic process	GO:0006195	109	0.017
organonitrogen compound metabolic process	GO:1901564	318	0.017
organophosphate catabolic process	GO:0046434	112	0.017
nuclear transcribed mrna catabolic process	GO:0000956	24	0.017
organic acid metabolic process	GO:0006082	103	0.017
negative regulation of cellular metabolic process	GO:0031324	382	0.017	Fly
negative regulation of epithelial cell proliferation	GO:0050680	4	0.017
regulation of cell cycle	GO:0051726	291	0.017
mitotic cell cycle phase transition	GO:0044772	138	0.017
cellular response to external stimulus	GO:0071496	66	0.017
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.017
carboxylic acid metabolic process	GO:0019752	92	0.017
positive regulation of response to stimulus	GO:0048584	323	0.017
single organism cellular localization	GO:1902580	180	0.017
single organism intracellular transport	GO:1902582	207	0.017
mesenchymal cell differentiation	GO:0048762	1	0.017
regulation of neurotransmitter secretion	GO:0046928	14	0.016
regulation of cell cycle process	GO:0010564	181	0.016
response to oxygen levels	GO:0070482	59	0.016
carbohydrate metabolic process	GO:0005975	82	0.016
positive regulation of rac gtpase activity	GO:0032855	8	0.016
negative regulation of cell differentiation	GO:0045596	143	0.016	Fly
purine nucleotide biosynthetic process	GO:0006164	29	0.016
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.016
organelle fission	GO:0048285	340	0.016
protein modification by small protein conjugation	GO:0032446	79	0.016
purine nucleoside catabolic process	GO:0006152	112	0.016
regulation of protein transport	GO:0051223	57	0.016	Mouse
regulation of nucleotide catabolic process	GO:0030811	48	0.016
negative regulation of cellular protein metabolic process	GO:0032269	85	0.016	Fly
dna conformation change	GO:0071103	105	0.016
response to wounding	GO:0009611	94	0.016	Human
regulation of secretion	GO:0051046	44	0.016	Mouse
regulation of actin filament length	GO:0030832	27	0.016
response to heat	GO:0009408	63	0.016
transcription from rna polymerase ii promoter	GO:0006366	368	0.015
neuron projection guidance	GO:0097485	241	0.015
anesthesia resistant memory	GO:0007615	6	0.015
regulation of cell substrate adhesion	GO:0010810	2	0.015
regulation of protein polymerization	GO:0032271	28	0.015
cellular amino acid metabolic process	GO:0006520	61	0.015
positive regulation of multicellular organismal process	GO:0051240	143	0.015
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.015	Fly
positive regulation of nucleotide catabolic process	GO:0030813	46	0.015
multicellular organism growth	GO:0035264	46	0.015
response to monosaccharide	GO:0034284	4	0.015
generation of precursor metabolites and energy	GO:0006091	42	0.015
positive regulation of cell proliferation	GO:0008284	47	0.015
negative regulation of cell communication	GO:0010648	223	0.015	Mouse Fly
regulation of mapk cascade	GO:0043408	92	0.014
positive regulation of cellular amine metabolic process	GO:0033240	0	0.014
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.014
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.014
regulation of cell projection assembly	GO:0060491	30	0.014
cellular response to nutrient levels	GO:0031669	62	0.014
cytoplasmic transport	GO:0016482	130	0.014
protein localization	GO:0008104	284	0.014	Mouse Fly
axonal defasciculation	GO:0007414	12	0.014
establishment of organelle localization	GO:0051656	122	0.014
cell growth	GO:0016049	108	0.014
cellular macromolecule localization	GO:0070727	220	0.014
negative regulation of growth	GO:0045926	84	0.014
regulation of locomotion	GO:0040012	42	0.014
purine ribonucleotide biosynthetic process	GO:0009152	28	0.014
compound eye photoreceptor development	GO:0042051	78	0.014
protein modification by small protein conjugation or removal	GO:0070647	106	0.014
blood circulation	GO:0008015	26	0.014
cellular cation homeostasis	GO:0030003	38	0.014
gene silencing	GO:0016458	138	0.014
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.014
regulation of apoptotic process	GO:0042981	130	0.014
regulation of actin filament polymerization	GO:0030833	25	0.014
mesenchymal cell development	GO:0014031	1	0.013
regulation of neuron apoptotic process	GO:0043523	16	0.013
positive regulation of growth	GO:0045927	75	0.013
endomembrane system organization	GO:0010256	119	0.013
myotube differentiation	GO:0014902	46	0.013
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.013
sensory perception of mechanical stimulus	GO:0050954	72	0.013
stem cell development	GO:0048864	79	0.013
cellular response to hormone stimulus	GO:0032870	44	0.013
axon extension	GO:0048675	32	0.013
response to other organism	GO:0051707	293	0.013
chromosome organization	GO:0051276	360	0.013
guanosine containing compound metabolic process	GO:1901068	74	0.013
response to organonitrogen compound	GO:0010243	75	0.013
dna packaging	GO:0006323	91	0.013
negative regulation of cell proliferation	GO:0008285	69	0.013	Fly
stem cell differentiation	GO:0048863	117	0.013
neuron apoptotic process	GO:0051402	17	0.013
muscle cell development	GO:0055001	50	0.013
response to biotic stimulus	GO:0009607	294	0.013
regulation of purine nucleotide metabolic process	GO:1900542	62	0.013
action potential	GO:0001508	13	0.013
regulation of g protein coupled receptor protein signaling pathway	GO:0008277	23	0.013
regulation of actin filament based process	GO:0032970	42	0.013
nucleoside triphosphate metabolic process	GO:0009141	120	0.012
establishment of synaptic vesicle localization	GO:0097480	50	0.012
axon midline choice point recognition	GO:0016199	26	0.012
intracellular transport	GO:0046907	228	0.012
positive regulation of cellular biosynthetic process	GO:0031328	316	0.012
cellular response to nitrogen compound	GO:1901699	51	0.012
carbohydrate derivative biosynthetic process	GO:1901137	85	0.012
neuron maturation	GO:0042551	31	0.012
extrinsic apoptotic signaling pathway	GO:0097191	1	0.012
positive regulation of cell projection organization	GO:0031346	29	0.012
telencephalon development	GO:0021537	2	0.012
regulation of muscle tissue development	GO:1901861	5	0.012
cell motility	GO:0048870	251	0.012
localization of cell	GO:0051674	257	0.012
negative regulation of rna metabolic process	GO:0051253	251	0.012
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.012
negative regulation of molecular function	GO:0044092	51	0.012	Fly
protein complex assembly	GO:0006461	200	0.012
gtp metabolic process	GO:0046039	72	0.012
positive regulation of cyclic nucleotide metabolic process	GO:0030801	9	0.012
divalent inorganic cation transport	GO:0072511	30	0.012
dna metabolic process	GO:0006259	227	0.012
organelle assembly	GO:0070925	198	0.012
rhythmic behavior	GO:0007622	76	0.012
positive regulation of protein modification process	GO:0031401	58	0.012
negative regulation of synapse assembly	GO:0051964	39	0.012
regulation of cell size	GO:0008361	63	0.012
protein polymerization	GO:0051258	42	0.012
embryo development ending in birth or egg hatching	GO:0009792	152	0.012
epithelium migration	GO:0090132	148	0.012
regulation of cell matrix adhesion	GO:0001952	1	0.012
cellular response to carbohydrate stimulus	GO:0071322	4	0.012
adult behavior	GO:0030534	137	0.012
response to fibroblast growth factor	GO:0071774	10	0.011
oxoacid metabolic process	GO:0043436	103	0.011
adherens junction organization	GO:0034332	27	0.011
body morphogenesis	GO:0010171	2	0.011
purine ribonucleoside catabolic process	GO:0046130	112	0.011
regulation of establishment of protein localization	GO:0070201	61	0.011	Mouse
negative regulation of epidermal growth factor receptor signaling pathway	GO:0042059	29	0.011
positive regulation of signal transduction	GO:0009967	223	0.011
hematopoietic or lymphoid organ development	GO:0048534	57	0.011
golgi organization	GO:0007030	66	0.011
regulation of lamellipodium assembly	GO:0010591	15	0.011
positive regulation of cellular catabolic process	GO:0031331	95	0.011
regulation of response to stress	GO:0080134	200	0.011	Human
skeletal muscle fiber development	GO:0048741	3	0.011
cellular metal ion homeostasis	GO:0006875	31	0.011
regulation of endocytosis	GO:0030100	37	0.011
carbohydrate derivative catabolic process	GO:1901136	118	0.011
death	GO:0016265	284	0.011	Fly
aging	GO:0007568	143	0.011
response to nutrient levels	GO:0031667	114	0.011
nuclear transport	GO:0051169	72	0.011
positive regulation of hydrolase activity	GO:0051345	78	0.011
forebrain development	GO:0030900	2	0.011
cortical cytoskeleton organization	GO:0030865	29	0.011
regulation of embryonic development	GO:0045995	68	0.011
negative regulation of cellular biosynthetic process	GO:0031327	277	0.011
positive regulation of gtp catabolic process	GO:0033126	43	0.011
regulation of intracellular transport	GO:0032386	64	0.011
ameboidal type cell migration	GO:0001667	151	0.011
positive regulation of intracellular transport	GO:0032388	42	0.011
response to nitrogen compound	GO:1901698	90	0.011
regulation of organ growth	GO:0046620	42	0.010
regulation of mitotic cell cycle	GO:0007346	190	0.010
nucleocytoplasmic transport	GO:0006913	72	0.010
cell cycle g1 s phase transition	GO:0044843	31	0.010
positive regulation of nucleotide metabolic process	GO:0045981	55	0.010
regulation of cell adhesion	GO:0030155	27	0.010
regulation of gtp catabolic process	GO:0033124	44	0.010
regulation of ion transport	GO:0043269	39	0.010
negative regulation of gene expression epigenetic	GO:0045814	77	0.010
nucleoside triphosphate catabolic process	GO:0009143	108	0.010
negative regulation of transcription dna templated	GO:0045892	237	0.010
cytokinesis	GO:0000910	90	0.010
regulation of protein phosphorylation	GO:0001932	64	0.010	Fly
regulation of cytoskeleton organization	GO:0051493	89	0.010
positive regulation of lipid catabolic process	GO:0050996	1	0.010
actin cytoskeleton reorganization	GO:0031532	22	0.010

tomosyn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.110
disease of cellular proliferation	DOID:14566	0.035
cancer	DOID:162	0.035
organ system cancer	DOID:0050686	0.026
nervous system disease	DOID:863	0.021
central nervous system disease	DOID:331	0.021
neurodegenerative disease	DOID:1289	0.021
cardiovascular system disease	DOID:1287	0.017

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