Drosophila melanogaster

0 known processes

Drep-4 (Dmel_CG9414)

DNA fragmentation factor-related protein 4

(Aliases: dCAD,drep4,Rep4,DREP-4,CG9414,Drep4,CAD,Dmel\CG9414)

Drep-4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cell differentiationGO:00455953020.271
establishment of localization in cellGO:00516494020.247
negative regulation of signal transductionGO:00099682060.231
regulation of cell deathGO:00109411730.221
immune system processGO:00023763470.214
negative regulation of signalingGO:00230572190.196
regulation of multicellular organismal developmentGO:20000264140.187
negative regulation of cell communicationGO:00106482230.170
compound eye developmentGO:00487493070.162
protein localizationGO:00081042840.158
small molecule metabolic processGO:00442813050.148
regulation of immune system processGO:00026821760.142
eye developmentGO:00016543230.132
compound eye morphogenesisGO:00017452490.131
intracellular signal transductionGO:00355563000.128
sensory organ morphogenesisGO:00905962600.127
regulation of intracellular signal transductionGO:19025312360.124
organic substance catabolic processGO:19015753080.123
Human
regulation of cell developmentGO:00602842150.121
regulation of programmed cell deathGO:00430671520.115
secretion by cellGO:00329401010.112
regulation of nervous system developmentGO:00519602480.100
regulation of cellular protein metabolic processGO:00322682430.100
actin filament based processGO:00300292200.098
regulation of immune responseGO:00507761180.098
positive regulation of cell communicationGO:00106472500.096
negative regulation of response to stimulusGO:00485852580.096
regulation of molecular functionGO:00650092170.092
regulation of neurogenesisGO:00507671580.084
regulation of response to stressGO:00801342000.082
negative regulation of multicellular organismal processGO:00512411420.081
actin filament organizationGO:00070151260.081
defense response to other organismGO:00985422250.079
positive regulation of response to stimulusGO:00485843230.077
organonitrogen compound metabolic processGO:19015643180.076
negative regulation of gene expressionGO:00106293870.073
defense responseGO:00069523000.073
negative regulation of cell differentiationGO:00455961430.072
regulation of localizationGO:00328792750.071
intracellular transportGO:00469072280.070
cell deathGO:00082192790.067
Human
organelle fissionGO:00482853400.067
forebrain developmentGO:003090020.066
positive regulation of immune responseGO:0050778630.066
small gtpase mediated signal transductionGO:0007264880.066
cell growthGO:00160491080.064
lipid metabolic processGO:00066291210.064
posttranscriptional regulation of gene expressionGO:00106081450.063
apoptotic processGO:00069151590.063
Human
regulation of transcription from rna polymerase ii promoterGO:00063573780.060
endocytosisGO:00068973100.058
regulation of defense responseGO:00313471020.058
eye morphogenesisGO:00485922600.057
negative regulation of cell deathGO:0060548810.055
vesicle mediated transportGO:00161923810.055
regulation of cellular amino acid metabolic processGO:000652100.053
positive regulation of developmental processGO:00510941430.053
organic substance transportGO:00717022570.053
regulation of phosphorus metabolic processGO:00511742100.053
immune response activating signal transductionGO:000275720.052
compound eye photoreceptor developmentGO:0042051780.052
cell type specific apoptotic processGO:0097285380.051
positive regulation of signal transductionGO:00099672230.050
regulation of catalytic activityGO:00507901850.050
negative regulation of apoptotic processGO:0043066630.050
carbohydrate derivative metabolic processGO:19011352170.049
deathGO:00162652840.049
Human
positive regulation of intracellular signal transductionGO:19025331160.048
homeostatic processGO:00425921990.048
mrna metabolic processGO:00160711240.047
cellular catabolic processGO:00442483720.047
Human
response to external biotic stimulusGO:00432072930.046
cellular component assembly involved in morphogenesisGO:00109271510.046
secretionGO:00469031090.046
cellular protein modification processGO:00064644380.046
innate immune responseGO:00450871440.044
nucleobase containing small molecule metabolic processGO:00550861740.044
carboxylic acid metabolic processGO:0019752920.043
regulation of ras protein signal transductionGO:0046578930.043
positive regulation of immune system processGO:0002684680.043
columnar cuboidal epithelial cell differentiationGO:00020652560.043
positive regulation of signalingGO:00230562430.042
nuclear divisionGO:00002803320.041
positive regulation of phosphorus metabolic processGO:00105621390.041
regulation of cellular amine metabolic processGO:003323830.040
actin cytoskeleton organizationGO:00300362060.040
ras protein signal transductionGO:0007265880.039
ribonucleotide metabolic processGO:00092591450.039
single organism behaviorGO:00447083910.039
regulation of transportGO:00510491810.038
organelle localizationGO:00516401480.037
single organism catabolic processGO:00447122280.037
regulation of establishment of protein localizationGO:0070201610.036
regulation of apoptotic processGO:00429811300.036
organic cyclic compound catabolic processGO:19013611680.036
Human
regulation of protein transportGO:0051223570.036
programmed cell deathGO:00125012570.035
Human
modification dependent macromolecule catabolic processGO:0043632790.035
chromosome segregationGO:00070591570.035
protein modification by small protein conjugation or removalGO:00706471060.035
negative regulation of programmed cell deathGO:0043069720.034
regulation of neuron projection developmentGO:0010975690.034
regulation of cellular ketone metabolic processGO:001056530.034
protein transportGO:00150311550.033
guanosine containing compound metabolic processGO:1901068740.033
macromolecule catabolic processGO:00090571610.033
Human
organonitrogen compound biosynthetic processGO:19015661170.033
adult locomotory behaviorGO:0008344760.033
regulation of cellular component sizeGO:0032535980.033
protein secretionGO:0009306450.033
compound eye photoreceptor cell differentiationGO:00017511400.032
organophosphate metabolic processGO:00196371950.032
gene silencingGO:00164581380.032
response to abiotic stimulusGO:00096283410.032
immune responseGO:00069552460.032
epithelial cell differentiationGO:00308553220.032
regulation of phosphate metabolic processGO:00192202100.032
transcription from rna polymerase ii promoterGO:00063663680.032
chromatin organizationGO:00063252070.032
multicellular organismal agingGO:00102591400.031
positive regulation of phosphate metabolic processGO:00459371390.031
phosphorylationGO:00163102940.031
negative regulation of immune system processGO:0002683500.031
organophosphate biosynthetic processGO:0090407460.030
cellular response to chemical stimulusGO:00708871990.030
organic acid metabolic processGO:00060821030.030
organonitrogen compound catabolic processGO:19015651280.030
eye photoreceptor cell differentiationGO:00017541450.030
protein phosphorylationGO:00064681690.030
regulation of epidermal growth factor receptor signaling pathwayGO:0042058420.029
regulation of response to external stimulusGO:00321011150.029
aromatic compound catabolic processGO:00194391660.029
Human
negative regulation of nervous system developmentGO:0051961920.029
cellularizationGO:0007349900.029
regulation of anatomical structure morphogenesisGO:00226032420.028
regulation of innate immune responseGO:0045088710.028
regulation of catabolic processGO:00098941700.028
telencephalon developmentGO:002153720.028
phagocytosisGO:00069092150.027
positive regulation of defense responseGO:0031349590.027
locomotory behaviorGO:00076261760.027
wnt signaling pathwayGO:0016055980.027
negative regulation of cellular component organizationGO:00511291080.027
nucleoside catabolic processGO:00091641120.027
vacuolar transportGO:0007034130.027
response to other organismGO:00517072930.027
developmental growthGO:00485892800.027
purine ribonucleotide catabolic processGO:00091541090.026
proteolysisGO:00065081920.026
catabolic processGO:00090564090.026
Human
meiotic nuclear divisionGO:00071261510.026
imaginal disc derived wing morphogenesisGO:00074763370.026
regulation of neuron differentiationGO:00456641030.026
developmental cell growthGO:0048588520.026
photoreceptor cell differentiationGO:00465301700.026
developmental programmed cell deathGO:00106231380.025
regulation of cell cycle processGO:00105641810.025
positive regulation of rna metabolic processGO:00512542710.025
protein modification processGO:00362114380.025
neuron deathGO:0070997270.025
regulation of cellular response to stressGO:0080135890.025
cell proliferationGO:00082832990.025
oxoacid metabolic processGO:00434361030.025
regionalizationGO:00030024160.025
organophosphate catabolic processGO:00464341120.024
regulation of wnt signaling pathwayGO:0030111680.024
nucleoside phosphate metabolic processGO:00067531620.024
negative regulation of nitrogen compound metabolic processGO:00511722650.024
positive regulation of apoptotic signaling pathwayGO:200123540.024
response to biotic stimulusGO:00096072940.024
gtp catabolic processGO:0006184720.024
sulfur compound metabolic processGO:0006790590.024
photoreceptor cell developmentGO:0042461960.024
single organism intracellular transportGO:19025822070.024
exocytosisGO:0006887280.024
regulation of synapse organizationGO:00508071100.024
mapk cascadeGO:00001651070.024
nucleoside triphosphate metabolic processGO:00091411200.024
purine nucleotide catabolic processGO:00061951090.023
regulation of erbb signaling pathwayGO:1901184420.023
carbohydrate derivative catabolic processGO:19011361180.023
regulation of protein metabolic processGO:00512462560.023
cellular metal ion homeostasisGO:0006875310.023
axonogenesisGO:00074092900.023
execution phase of apoptosisGO:009719470.023
Human
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.023
cytoplasmic transportGO:00164821300.023
growthGO:00400073590.022
negative regulation of nucleic acid templated transcriptionGO:19035072400.022
eye photoreceptor cell developmentGO:0042462810.022
ribonucleoside triphosphate metabolic processGO:00091991190.022
purine ribonucleoside metabolic processGO:00461281270.022
regulation of cytoskeleton organizationGO:0051493890.022
positive regulation of molecular functionGO:00440931360.022
cell maturationGO:00484691440.022
chemical homeostasisGO:0048878920.022
open tracheal system developmentGO:00074242040.021
response to organic substanceGO:00100332840.021
regulation of organelle organizationGO:00330431960.021
establishment of protein localizationGO:00451841630.021
negative regulation of cellular biosynthetic processGO:00313272770.021
positive regulation of cellular catabolic processGO:0031331950.021
wing disc morphogenesisGO:00074723440.021
response to light stimulusGO:00094161240.021
regulation of mapk cascadeGO:0043408920.021
cation transmembrane transportGO:0098655880.021
extrinsic apoptotic signaling pathwayGO:009719110.021
cellular homeostasisGO:0019725800.021
glycosyl compound catabolic processGO:19016581120.021
response to nitrogen compoundGO:1901698900.020
ribonucleotide catabolic processGO:00092611090.020
positive regulation of phosphorylationGO:0042327870.020
nurse cell apoptotic processGO:0045476170.020
negative regulation of transcription dna templatedGO:00458922370.020
mitotic spindle organizationGO:00070522200.020
nucleotide catabolic processGO:00091661090.020
rna processingGO:00063961470.019
positive regulation of cellular protein metabolic processGO:00322701180.019
positive regulation of cell deathGO:0010942690.019
negative regulation of molecular functionGO:0044092510.019
adult behaviorGO:00305341370.019
regulation of immune effector processGO:0002697520.019
purine nucleoside triphosphate catabolic processGO:00091461080.019
gtp metabolic processGO:0046039720.019
cellular response to endogenous stimulusGO:0071495800.019
cell adhesionGO:00071551360.019
regulation of hydrolase activityGO:0051336970.019
positive regulation of cell differentiationGO:0045597640.018
purine ribonucleotide metabolic processGO:00091501450.018
protein heterooligomerizationGO:005129140.018
steroid catabolic processGO:000670610.018
tissue morphogenesisGO:00487292970.018
positive regulation of cell migrationGO:003033520.018
cellular amine metabolic processGO:0044106120.018
regulation of anatomical structure sizeGO:00900661630.018
response to radiationGO:00093141550.018
camera type eye developmentGO:004301040.018
rho protein signal transductionGO:0007266140.018
post embryonic appendage morphogenesisGO:00351203850.018
nucleoside triphosphate catabolic processGO:00091431080.018
response to monosaccharideGO:003428440.018
positive regulation of catabolic processGO:00098961050.018
cellular ketone metabolic processGO:0042180240.018
organic hydroxy compound metabolic processGO:1901615830.018
purine ribonucleoside catabolic processGO:00461301120.018
positive regulation of nervous system developmentGO:0051962690.017
inorganic ion transmembrane transportGO:0098660730.017
cellular amino acid metabolic processGO:0006520610.017
negative regulation of cellular metabolic processGO:00313243820.017
purine containing compound metabolic processGO:00725211550.017
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.017
spermatid differentiationGO:00485151140.017
regulation of organ morphogenesisGO:2000027780.017
determination of adult lifespanGO:00083401370.017
positive regulation of hydrolase activityGO:0051345780.017
response to hexoseGO:000974630.017
g protein coupled receptor signaling pathwayGO:00071861360.017
regulation of response to biotic stimulusGO:0002831630.017
positive regulation of cellular biosynthetic processGO:00313283160.017
regulation of cellular localizationGO:00603411360.016
regulation of phosphorylationGO:00423251470.016
carbohydrate derivative biosynthetic processGO:1901137850.016
positive regulation of protein metabolic processGO:00512471280.016
regulation of actin cytoskeleton organizationGO:0032956420.016
nucleotide metabolic processGO:00091171610.016
eggshell formationGO:00307031050.016
cellular protein localizationGO:00346131600.016
epithelium migrationGO:00901321480.016
positive regulation of cell developmentGO:0010720610.016
positive regulation of nucleotide catabolic processGO:0030813460.016
covalent chromatin modificationGO:00165691060.016
heterocycle catabolic processGO:00467001660.016
Human
mitotic sister chromatid segregationGO:0000070870.016
cell divisionGO:00513012480.016
embryo development ending in birth or egg hatchingGO:00097921520.016
wound healingGO:0042060750.016
negative regulation of cell developmentGO:0010721620.016
nitrogen compound transportGO:0071705850.016
positive regulation of gene expressionGO:00106282900.016
negative regulation of macromolecule biosynthetic processGO:00105582700.016
endomembrane system organizationGO:00102561190.016
regulation of actin filament based processGO:0032970420.016
enzyme linked receptor protein signaling pathwayGO:00071671790.016
signal transduction by phosphorylationGO:00230141070.016
purine ribonucleoside triphosphate metabolic processGO:00092051190.016
taxisGO:00423303040.016
response to glucoseGO:000974920.016
immune system developmentGO:0002520570.016
positive regulation of mapk cascadeGO:0043410630.015
cation transportGO:00068121100.015
regulation of cell sizeGO:0008361630.015
negative regulation of intracellular signal transductionGO:1902532570.015
dendrite developmentGO:00163582040.015
hematopoietic or lymphoid organ developmentGO:0048534570.015
negative regulation of developmental processGO:00510932010.015
hindbrain developmentGO:003090220.015
purine containing compound catabolic processGO:00725231120.015
spermatid developmentGO:0007286980.015
regulation of gtp catabolic processGO:0033124440.015
regulation of gene expression epigeneticGO:00400291280.015
nucleobase containing compound catabolic processGO:00346551650.015
Human
learning or memoryGO:00076111410.015
cellular response to dna damage stimulusGO:00069742230.015
regulation of purine nucleotide catabolic processGO:0033121480.015
male gamete generationGO:00482322010.015
cellular response to nitrogen compoundGO:1901699510.015
positive regulation of proteolysisGO:0045862520.015
regulation of cell substrate adhesionGO:001081020.015
cellular lipid metabolic processGO:0044255830.015
ribonucleoside metabolic processGO:00091191270.015
regulation of cell projection organizationGO:0031344920.015
stem cell differentiationGO:00488631170.015
regulation of protein modification processGO:00313991120.014
response to bacteriumGO:00096171980.014
gliogenesisGO:0042063800.014
chromosome organizationGO:00512763600.014
Human
positive regulation of cellular amino acid metabolic processGO:004576400.014
embryonic morphogenesisGO:00485982060.014
regulation of cell proliferationGO:00421271630.014
filopodium assemblyGO:0046847330.014
ribose phosphate metabolic processGO:00196931450.014
response to lipopolysaccharideGO:003249640.014
purine ribonucleoside triphosphate catabolic processGO:00092071080.014
ion transmembrane transportGO:00342201220.014
ribonucleoside triphosphate catabolic processGO:00092031080.014
peptidyl amino acid modificationGO:00181931050.014
regulation of lipid metabolic processGO:0019216150.014
establishment of planar polarityGO:0001736870.014
nucleoside metabolic processGO:00091161270.014
translationGO:0006412690.014
regulation of map kinase activityGO:0043405170.014
regulation of neuron deathGO:1901214260.014
guanosine containing compound catabolic processGO:1901069740.014
negative regulation of homeostatic processGO:003284520.013
negative regulation of nucleobase containing compound metabolic processGO:00459342610.013
regulation of small gtpase mediated signal transductionGO:0051056930.013
rna splicingGO:0008380830.013
amide biosynthetic processGO:0043604420.013
spermatogenesisGO:00072832000.013
negative regulation of biosynthetic processGO:00098902770.013
flight behaviorGO:0007629260.013
response to organic cyclic compoundGO:0014070890.013
regulation of purine nucleotide metabolic processGO:1900542620.013
positive regulation of catalytic activityGO:00430851180.013
positive regulation of nucleobase containing compound metabolic processGO:00459353320.013
regulation of protein phosphorylationGO:0001932640.013
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188170.013
cell projection assemblyGO:0030031940.013
mesenchymal cell differentiationGO:004876210.013
positive regulation of cellular component organizationGO:00511301560.013
imaginal disc derived appendage developmentGO:00487373990.013
positive regulation of cell motilityGO:200014730.013
posttranscriptional gene silencing by rnaGO:0035194450.013
positive regulation of transportGO:0051050920.013
ribonucleoside catabolic processGO:00424541120.013
positive regulation of gtp catabolic processGO:0033126430.012
retina development in camera type eyeGO:006004140.012
positive regulation of gtpase activityGO:0043547430.012
positive regulation of nucleoside metabolic processGO:0045979470.012
epithelial cell developmentGO:00020642740.012
response to oxygen containing compoundGO:19017002000.012
kidney developmentGO:000182230.012
compound eye retinal cell programmed cell deathGO:0046667230.012
regulation of kinase activityGO:0043549530.012
regulation of secretionGO:0051046440.012
neuron remodelingGO:0016322290.012
mesenchymal cell developmentGO:001403110.012
peptide metabolic processGO:0006518800.012
positive regulation of multicellular organismal processGO:00512401430.012
regulation of cell morphogenesis involved in differentiationGO:0010769610.012
response to endogenous stimulusGO:00097191190.012
positive regulation of nitrogen compound metabolic processGO:00511733540.012
glycosyl compound metabolic processGO:19016571270.012
cellular response to organic substanceGO:00713101320.012
positive regulation of ras protein signal transductionGO:0046579430.012
regulation of growthGO:00400082330.012
positive regulation of macromolecule metabolic processGO:00106044050.012
purine nucleoside triphosphate metabolic processGO:00091441190.012
negative regulation of catalytic activityGO:0043086420.012
ion transportGO:00068111450.012
positive regulation of cell projection organizationGO:0031346290.012
single organism biosynthetic processGO:00447112060.012
response to ionizing radiationGO:0010212320.012
cell migrationGO:00164772380.012
response to organonitrogen compoundGO:0010243750.012
regulation of cell cycleGO:00517262910.012
gene silencing by rnaGO:0031047570.012
regulation of cell divisionGO:0051302720.012
nucleoside phosphate catabolic processGO:19012921100.012
regulation of cellular component biogenesisGO:00440872010.012
cellular response to carbohydrate stimulusGO:007132240.011
chromatin modificationGO:00165681470.011
regulation of developmental growthGO:00486381740.011
neuron maturationGO:0042551310.011
regulation of nucleotide catabolic processGO:0030811480.011
central nervous system developmentGO:00074172010.011
cellular nitrogen compound catabolic processGO:00442701650.011
Human
regulation of multi organism processGO:00439001310.011
regulation of meiosisGO:004002030.011
muscle cell differentiationGO:00426921030.011
negative regulation of erbb signaling pathwayGO:1901185290.011
regulation of protein localizationGO:0032880760.011
epidermal growth factor receptor signaling pathwayGO:0007173580.011
camera type eye morphogenesisGO:004859320.011
regulation of ras gtpase activityGO:0032318380.011
immune response regulating signaling pathwayGO:000276420.011
cellular response to oxygen containing compoundGO:1901701790.011
neuron projection guidanceGO:00974852410.011
positive regulation of apoptotic processGO:0043065470.011
cellular chemical homeostasisGO:0055082400.011
positive regulation of purine nucleotide catabolic processGO:0033123460.011
single organism cellular localizationGO:19025801800.011
endosomal transportGO:0016197440.011
regulation of mitotic cell cycleGO:00073461900.011
negative regulation of protein metabolic processGO:0051248850.011
regulation of transferase activityGO:0051338580.011
developmental growth involved in morphogenesisGO:0060560650.011
negative regulation of neurogenesisGO:0050768530.011
metal ion homeostasisGO:0055065440.011
erbb signaling pathwayGO:0038127580.010
negative regulation of epidermal growth factor receptor signaling pathwayGO:0042059290.010
meiotic cell cycleGO:00513211710.010
protein k48 linked ubiquitinationGO:007093630.010
cognitionGO:00508901410.010
vesicle localizationGO:0051648550.010
purine nucleotide metabolic processGO:00061631460.010
cell motilityGO:00488702510.010
biological adhesionGO:00226101380.010
response to woundingGO:0009611940.010
proteolysis involved in cellular protein catabolic processGO:0051603830.010
columnar cuboidal epithelial cell developmentGO:00020662490.010
mitotic nuclear divisionGO:00070672130.010
regulation of mrna metabolic processGO:1903311720.010
establishment of tissue polarityGO:0007164870.010

Drep-4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.019
disease of metabolismDOID:001466700.012
inherited metabolic disorderDOID:65500.012
nervous system diseaseDOID:86300.012
musculoskeletal system diseaseDOID:1700.011