Drosophila melanogaster

86 known processes

sisA (Dmel_CG1641)

sisterless A

(Aliases: sis-A,sisa,Dmel\CG1641,sis-a,CG1641,sis a,sis A)

sisA biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of rna metabolic processGO:00512542710.150
small molecule metabolic processGO:00442813050.132
mating behaviorGO:00076171060.117
organonitrogen compound metabolic processGO:19015643180.106
carbohydrate derivative metabolic processGO:19011352170.102
sensory perceptionGO:00076001960.101
sensory perception of chemical stimulusGO:00076061160.090
single organism catabolic processGO:00447122280.088
neurological system processGO:00508773580.086
regulation of nervous system developmentGO:00519602480.084
response to abiotic stimulusGO:00096283410.082
positive regulation of nitrogen compound metabolic processGO:00511733540.082
regulation of localizationGO:00328792750.080
multi multicellular organism processGO:00447061230.078
positive regulation of developmental processGO:00510941430.077
cell migrationGO:00164772380.076
compound eye morphogenesisGO:00017452490.074
regulation of gene expression epigeneticGO:00400291280.074
positive regulation of cellular biosynthetic processGO:00313283160.072
negative regulation of rna biosynthetic processGO:19026792400.072
regulation of multicellular organismal developmentGO:20000264140.071
catabolic processGO:00090564090.071
positive regulation of macromolecule biosynthetic processGO:00105572830.068
regulation of intracellular signal transductionGO:19025312360.067
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.066
positive regulation of biosynthetic processGO:00098913160.066
positive regulation of macromolecule metabolic processGO:00106044050.064
reproductive behaviorGO:00190981220.063
chromatin organizationGO:00063252070.063
cell motilityGO:00488702510.061
body morphogenesisGO:001017120.061
epithelial cell differentiationGO:00308553220.061
negative regulation of nucleobase containing compound metabolic processGO:00459342610.059
positive regulation of response to stimulusGO:00485843230.059
nucleotide metabolic processGO:00091171610.059
positive regulation of nucleobase containing compound metabolic processGO:00459353320.059
localization of cellGO:00516742570.059
heterocycle catabolic processGO:00467001660.057
aromatic compound catabolic processGO:00194391660.056
matingGO:00076181200.055
positive regulation of rna biosynthetic processGO:19026802660.055
negative regulation of transcription dna templatedGO:00458922370.053
negative regulation of developmental processGO:00510932010.053
notch signaling pathwayGO:00072191200.052
salivary gland morphogenesisGO:00074351450.052
negative regulation of nucleic acid templated transcriptionGO:19035072400.052
regulation of cellular catabolic processGO:00313291570.051
negative regulation of macromolecule biosynthetic processGO:00105582700.051
nucleobase containing compound catabolic processGO:00346551650.051
single organism intracellular transportGO:19025822070.050
hindbrain developmentGO:003090220.050
cellular response to chemical stimulusGO:00708871990.050
dorsal ventral pattern formationGO:00099531330.049
chemotaxisGO:00069352490.049
protein modification processGO:00362114380.048
response to organic substanceGO:00100332840.048
cellular nitrogen compound catabolic processGO:00442701650.047
stem cell differentiationGO:00488631170.047
positive regulation of cellular amino acid metabolic processGO:004576400.046
regulation of cell developmentGO:00602842150.046
regulation of notch signaling pathwayGO:00085931000.045
axon guidanceGO:00074112330.044
embryonic development via the syncytial blastodermGO:00017001480.044
histone modificationGO:00165701060.043
programmed cell deathGO:00125012570.043
negative regulation of nitrogen compound metabolic processGO:00511722650.042
deathGO:00162652840.042
positive regulation of cellular component organizationGO:00511301560.042
positive regulation of signal transductionGO:00099672230.041
actin filament based processGO:00300292200.041
negative regulation of cell differentiationGO:00455961430.041
cellular catabolic processGO:00442483720.040
lateral inhibitionGO:00463312060.040
negative regulation of cellular metabolic processGO:00313243820.040
enzyme linked receptor protein signaling pathwayGO:00071671790.040
negative regulation of biosynthetic processGO:00098902770.040
carboxylic acid metabolic processGO:0019752920.039
eye morphogenesisGO:00485922600.039
organonitrogen compound catabolic processGO:19015651280.039
phosphorylationGO:00163102940.039
regulation of catabolic processGO:00098941700.038
exocrine system developmentGO:00352721620.038
tube developmentGO:00352952440.037
cardiovascular system developmentGO:0072358820.037
courtship behaviorGO:0007619680.037
tissue morphogenesisGO:00487292970.037
covalent chromatin modificationGO:00165691060.037
tube morphogenesisGO:00352391910.037
organic cyclic compound catabolic processGO:19013611680.036
circulatory system developmentGO:0072359820.035
regulation of immune system processGO:00026821760.035
positive regulation of gene expressionGO:00106282900.035
gland morphogenesisGO:00226121450.035
ribonucleotide metabolic processGO:00092591450.034
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.034
compound eye developmentGO:00487493070.034
negative regulation of cell communicationGO:00106482230.034
positive regulation of transcription dna templatedGO:00458932660.034
regulation of cell proliferationGO:00421271630.034
axon developmentGO:00615642970.033
regionalizationGO:00030024160.033
cellular amino acid metabolic processGO:0006520610.032
oxoacid metabolic processGO:00434361030.032
regulation of cell cycle processGO:00105641810.032
purine nucleotide metabolic processGO:00061631460.032
negative regulation of multicellular organismal processGO:00512411420.032
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.032
morphogenesis of an epitheliumGO:00020092760.032
positive regulation of phosphorus metabolic processGO:00105621390.032
cell deathGO:00082192790.032
embryo development ending in birth or egg hatchingGO:00097921520.032
gland developmentGO:00487321910.031
regulation of cellular amino acid metabolic processGO:000652100.031
regulation of behaviorGO:0050795750.031
negative regulation of response to stimulusGO:00485852580.031
developmental growthGO:00485892800.031
mesenchymal cell developmentGO:001403110.031
cellular protein modification processGO:00064644380.031
photoreceptor cell differentiationGO:00465301700.031
ribose phosphate metabolic processGO:00196931450.030
nucleobase containing small molecule metabolic processGO:00550861740.030
positive regulation of catalytic activityGO:00430851180.030
head developmentGO:00603221350.030
regulation of cellular response to stressGO:0080135890.030
regulation of molecular functionGO:00650092170.030
regulation of developmental growthGO:00486381740.030
protein complex biogenesisGO:00702712010.030
regulation of neuron differentiationGO:00456641030.029
chemical homeostasisGO:0048878920.029
columnar cuboidal epithelial cell differentiationGO:00020652560.029
purine ribonucleoside triphosphate catabolic processGO:00092071080.029
purine nucleoside metabolic processGO:00422781270.029
telencephalon developmentGO:002153720.029
organic substance transportGO:00717022570.029
multi organism behaviorGO:00517051750.029
negative regulation of cellular biosynthetic processGO:00313272770.029
negative regulation of rna metabolic processGO:00512532510.028
nucleoside catabolic processGO:00091641120.028
ribonucleoside triphosphate catabolic processGO:00092031080.028
nephron developmentGO:007200630.028
l amino acid importGO:004309220.028
imaginal disc derived appendage morphogenesisGO:00351143950.028
regulation of chromatin silencingGO:0031935360.028
sex determinationGO:0007530180.028
vesicle mediated transportGO:00161923810.028
intracellular transportGO:00469072280.027
developmental programmed cell deathGO:00106231380.026
nucleoside phosphate metabolic processGO:00067531620.026
organic acid metabolic processGO:00060821030.026
response to oxygen containing compoundGO:19017002000.026
organelle fissionGO:00482853400.026
ribonucleoside triphosphate metabolic processGO:00091991190.025
organelle localizationGO:00516401480.025
protein complex assemblyGO:00064612000.025
embryonic morphogenesisGO:00485982060.025
purine nucleotide catabolic processGO:00061951090.025
positive regulation of cell communicationGO:00106472500.025
transcription from rna polymerase ii promoterGO:00063663680.025
positive regulation of signalingGO:00230562430.024
positive regulation of cellular amine metabolic processGO:003324000.024
positive regulation of phosphate metabolic processGO:00459371390.024
neuron projection guidanceGO:00974852410.024
developmental maturationGO:00217001720.024
sensory perception of mechanical stimulusGO:0050954720.024
protein localizationGO:00081042840.024
hematopoietic or lymphoid organ developmentGO:0048534570.024
mesenchymal cell differentiationGO:004876210.023
purine ribonucleotide catabolic processGO:00091541090.023
nucleoside triphosphate metabolic processGO:00091411200.023
endocytosisGO:00068973100.023
nucleoside phosphate catabolic processGO:19012921100.023
purine nucleoside triphosphate catabolic processGO:00091461080.023
actin cytoskeleton organizationGO:00300362060.023
organic substance catabolic processGO:19015753080.023
regulation of neurogenesisGO:00507671580.023
multi organism reproductive behaviorGO:00447051210.023
salivary gland histolysisGO:0035070880.023
cellular protein localizationGO:00346131600.023
histolysisGO:00075591020.023
purine ribonucleotide metabolic processGO:00091501450.023
purine containing compound catabolic processGO:00725231120.022
response to bacteriumGO:00096171980.022
forebrain developmentGO:003090020.022
organophosphate catabolic processGO:00464341120.022
positive regulation of molecular functionGO:00440931360.022
columnar cuboidal epithelial cell developmentGO:00020662490.022
nucleoside triphosphate catabolic processGO:00091431080.022
carbohydrate derivative catabolic processGO:19011361180.022
regulation of cellular ketone metabolic processGO:001056530.022
macromolecule catabolic processGO:00090571610.022
protein localization to organelleGO:0033365820.022
response to external biotic stimulusGO:00432072930.021
positive regulation of multicellular organismal processGO:00512401430.021
regulation of cell differentiationGO:00455953020.021
mrna processingGO:00063971040.021
purine ribonucleoside triphosphate metabolic processGO:00092051190.021
regulation of organelle organizationGO:00330431960.021
cell cell signaling involved in cell fate commitmentGO:00451682100.021
regulation of transportGO:00510491810.021
male courtship behaviorGO:0008049630.021
negative regulation of gene expressionGO:00106293870.021
appendage morphogenesisGO:00351073970.021
regulation of cellular amine metabolic processGO:003323830.021
cellular macromolecule localizationGO:00707272200.021
ovarian follicle cell developmentGO:00307072480.020
positive regulation of nervous system developmentGO:0051962690.020
stem cell proliferationGO:0072089880.020
digestive tract developmentGO:00485651490.020
salivary gland cell autophagic cell deathGO:0035071830.020
camera type eye morphogenesisGO:004859320.020
chromatin modificationGO:00165681470.020
regulation of catalytic activityGO:00507901850.020
positive regulation of nucleic acid templated transcriptionGO:19035082660.020
taxisGO:00423303040.020
single organism behaviorGO:00447083910.020
regulation of phosphorus metabolic processGO:00511742100.020
intracellular signal transductionGO:00355563000.020
dendrite developmentGO:00163582040.020
positive regulation of purine nucleotide metabolic processGO:1900544550.020
salivary gland developmentGO:00074311620.020
positive regulation of nucleoside metabolic processGO:0045979470.020
organophosphate metabolic processGO:00196371950.020
regulation of establishment of protein localizationGO:0070201610.020
mushroom body developmentGO:0016319700.020
nucleoside metabolic processGO:00091161270.020
purine ribonucleoside catabolic processGO:00461301120.019
nephron epithelium morphogenesisGO:007208830.019
regulation of gene silencingGO:0060968630.019
purine ribonucleoside metabolic processGO:00461281270.019
negative regulation of nervous system developmentGO:0051961920.019
response to biotic stimulusGO:00096072940.019
phagocytosisGO:00069092150.019
purine nucleoside catabolic processGO:00061521120.019
autophagic cell deathGO:0048102830.019
nuclear transportGO:0051169720.019
defense response to bacteriumGO:00427421780.019
negative regulation of signalingGO:00230572190.019
glycosyl compound catabolic processGO:19016581120.019
regulation of epithelial cell differentiationGO:003085640.019
kidney developmentGO:000182230.019
regulation of response to stressGO:00801342000.019
l glutamate importGO:005193810.018
secondary metabolic processGO:0019748750.018
ribonucleotide catabolic processGO:00092611090.018
tissue deathGO:00162711020.018
autophagyGO:00069141080.018
response to radiationGO:00093141550.018
cell maturationGO:00484691440.018
establishment of protein localizationGO:00451841630.018
wing disc pattern formationGO:0035222660.018
multicellular organismal reproductive behaviorGO:00330571100.018
axonogenesisGO:00074092900.018
sensory perception of smellGO:0007608800.018
protein phosphorylationGO:00064681690.018
ribonucleoside catabolic processGO:00424541120.018
positive regulation of transportGO:0051050920.017
neural precursor cell proliferationGO:0061351750.017
cellular response to radiationGO:0071478520.017
regulation of protein metabolic processGO:00512462560.017
regulation of mitotic cell cycleGO:00073461900.017
eye developmentGO:00016543230.017
connective tissue developmentGO:006144830.017
regulation of antimicrobial humoral responseGO:0002759500.017
single organism cellular localizationGO:19025801800.017
protein catabolic processGO:00301631010.017
regulation of cellular component sizeGO:0032535980.016
actin filament organizationGO:00070151260.016
epithelial cell developmentGO:00020642740.016
positive regulation of cell differentiationGO:0045597640.016
regulation of mitosisGO:0007088560.016
vitamin metabolic processGO:000676620.016
smoothened signaling pathwayGO:0007224490.016
protein transportGO:00150311550.016
cellular response to organic substanceGO:00713101320.016
urogenital system developmentGO:0001655720.016
sterol homeostasisGO:005509240.016
response to oxidative stressGO:0006979860.016
response to hexoseGO:000974630.016
imaginal disc pattern formationGO:0007447910.016
negative regulation of signal transductionGO:00099682060.016
intracellular protein transportGO:00068861040.016
nuclear importGO:0051170510.016
mitotic nuclear divisionGO:00070672130.015
histone h4 k16 acetylationGO:004398440.015
ras protein signal transductionGO:0007265880.015
negative regulation of gene expression epigeneticGO:0045814770.015
regulation of nucleotide metabolic processGO:0006140620.015
cellular response to oxygen containing compoundGO:1901701790.015
stem cell fate commitmentGO:0048865250.015
regulation of transcription from rna polymerase ii promoterGO:00063573780.015
regulation of cell deathGO:00109411730.015
embryonic hindgut morphogenesisGO:0048619480.015
larval behaviorGO:0030537420.015
amine metabolic processGO:0009308120.015
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377730.015
positive regulation of hydrolase activityGO:0051345780.015
response to endogenous stimulusGO:00097191190.015
regulation of programmed cell deathGO:00430671520.015
dendrite morphogenesisGO:00488131990.015
protein targeting to nucleusGO:0044744510.015
single organism biosynthetic processGO:00447112060.015
growthGO:00400073590.015
secondary metabolite biosynthetic processGO:0044550240.015
estrogen metabolic processGO:000821010.015
protein targetingGO:0006605640.015
nephron morphogenesisGO:007202830.015
cellular ketone metabolic processGO:0042180240.015
regulation of mrna metabolic processGO:1903311720.015
anatomical structure homeostasisGO:0060249970.015
rna splicingGO:0008380830.015
eye photoreceptor cell differentiationGO:00017541450.015
regulation of cellular protein metabolic processGO:00322682430.015
single organism nuclear importGO:1902593510.015
sensory organ morphogenesisGO:00905962600.014
response to organic cyclic compoundGO:0014070890.014
somatic muscle developmentGO:0007525660.014
brain developmentGO:00074201200.014
cellular response to dna damage stimulusGO:00069742230.014
regulation of hydrolase activityGO:0051336970.014
kidney morphogenesisGO:006099330.014
internal protein amino acid acetylationGO:0006475380.014
regulation of anatomical structure sizeGO:00900661630.014
positive regulation of cell migrationGO:003033520.014
establishment of protein localization to organelleGO:0072594620.014
cell divisionGO:00513012480.014
nucleotide catabolic processGO:00091661090.014
respiratory system developmentGO:00605412130.014
cell fate specificationGO:0001708710.014
positive regulation of cellular catabolic processGO:0031331950.014
response to lipopolysaccharideGO:003249640.014
cell fate determinationGO:0001709910.014
positive regulation of cell proliferationGO:0008284470.014
compound eye photoreceptor cell differentiationGO:00017511400.014
negative regulation of cell deathGO:0060548810.014
negative regulation of cell developmentGO:0010721620.014
developmental pigmentationGO:0048066680.014
gtp metabolic processGO:0046039720.014
regulation of phosphate metabolic processGO:00192202100.014
regulation of protein localizationGO:0032880760.014
spindle organizationGO:00070512530.014
memoryGO:0007613940.014
morphogenesis of embryonic epitheliumGO:0016331940.014
cellular macromolecule catabolic processGO:00442651360.014
limb morphogenesisGO:003510810.013
mrna metabolic processGO:00160711240.013
regulation of cell cycleGO:00517262910.013
regulation of endocytosisGO:0030100370.013
regulation of cell growthGO:0001558430.013
regulation of mapk cascadeGO:0043408920.013
pigmentationGO:0043473750.013
segmentationGO:00352822070.013
epidermal growth factor receptor signaling pathwayGO:0007173580.013
rna splicing via transesterification reactionsGO:0000375730.013
small gtpase mediated signal transductionGO:0007264880.013
axis specificationGO:00097981670.013
regulation of alternative mrna splicing via spliceosomeGO:0000381600.013
proteolysisGO:00065081920.013
outflow tract morphogenesisGO:000315140.013
protein importGO:0017038550.013
ribonucleoside metabolic processGO:00091191270.013
mitotic spindle organizationGO:00070522200.013
hemopoiesisGO:0030097460.013
positive regulation of organelle organizationGO:0010638650.013
cellular amine metabolic processGO:0044106120.013
anterior malpighian tubule developmentGO:0061327120.013
response to nitrogen compoundGO:1901698900.013
cellular homeostasisGO:0019725800.013
segment specificationGO:0007379330.013
cellular response to nitrogen compoundGO:1901699510.013
carbohydrate derivative biosynthetic processGO:1901137850.013
protein import into nucleusGO:0006606510.013
cellular amide metabolic processGO:0043603800.012
positive regulation of cell motilityGO:200014730.012
open tracheal system developmentGO:00074242040.012
positive regulation of cell developmentGO:0010720610.012
regulation of cellular component biogenesisGO:00440872010.012
regulation of apoptotic processGO:00429811300.012
nephron tubule developmentGO:007208030.012
mrna splicing via spliceosomeGO:0000398730.012
establishment of localization in cellGO:00516494020.012
positive regulation of catabolic processGO:00098961050.012
rho protein signal transductionGO:0007266140.012
appendage developmentGO:00487364010.012
regulation of axon extension involved in axon guidanceGO:004884140.012
response to monosaccharideGO:003428440.012
muscle cell differentiationGO:00426921030.012
chromosome organizationGO:00512763600.012
regulation of epidermal growth factor receptor signaling pathwayGO:0042058420.012
regulation of nucleoside metabolic processGO:0009118500.012
sensory perception of painGO:001923340.012
defense response to other organismGO:00985422250.012
organ growthGO:0035265560.012
purine nucleoside triphosphate metabolic processGO:00091441190.012
regulation of nuclear divisionGO:0051783580.012
camera type eye developmentGO:004301040.012
regulation of cell projection organizationGO:0031344920.012
digestive system developmentGO:00551231490.012
cellular response to endogenous stimulusGO:0071495800.012
positive regulation of cellular protein metabolic processGO:00322701180.011
anterior posterior pattern specificationGO:00099521360.011
cell projection assemblyGO:0030031940.011
wing disc morphogenesisGO:00074723440.011
response to glucoseGO:000974920.011
cholesterol transportGO:003030120.011
multicellular organismal agingGO:00102591400.011
dorsal ventral pattern formation imaginal discGO:0007450510.011
positive regulation of peptidyl tyrosine phosphorylationGO:005073140.011
tissue migrationGO:00901301550.011
malpighian tubule morphogenesisGO:0007443440.011
peptidyl amino acid modificationGO:00181931050.011
cranial nerve developmentGO:002154510.011
negative regulation of notch signaling pathwayGO:0045746410.011
regulation of synapse assemblyGO:0051963940.011
establishment of organelle localizationGO:00516561220.011
nucleocytoplasmic transportGO:0006913720.011
androgen metabolic processGO:000820910.011
sensory perception of soundGO:0007605560.011
eye antennal disc developmentGO:0035214600.011
protein localization to nucleusGO:0034504550.011
cholesterol homeostasisGO:004263230.011
negative regulation of neurogenesisGO:0050768530.011
nephron epithelium developmentGO:007200930.011
wing disc dorsal ventral pattern formationGO:0048190470.011
female mating behaviorGO:0060180300.011
peptide metabolic processGO:0006518800.011
limb developmentGO:006017310.011
positive regulation of cell deathGO:0010942690.011
glycosyl compound metabolic processGO:19016571270.011
regulation of cell divisionGO:0051302720.011
ribose phosphate biosynthetic processGO:0046390280.011
chaeta morphogenesisGO:0008407420.011
response to alcoholGO:0097305950.011
internal peptidyl lysine acetylationGO:0018393380.011
oocyte developmentGO:00485991240.010
cellular response to nutrient levelsGO:0031669620.010
single organism carbohydrate metabolic processGO:0044723720.010
cellular component assembly involved in morphogenesisGO:00109271510.010
stem cell maintenanceGO:0019827670.010
regulation of response to external stimulusGO:00321011150.010
rna processingGO:00063961470.010
guanosine containing compound metabolic processGO:1901068740.010
malpighian tubule developmentGO:0072002640.010
cytoplasmic transportGO:00164821300.010
response to decreased oxygen levelsGO:0036293580.010
regulation of heart morphogenesisGO:200082630.010
eye antennal disc morphogenesisGO:0007455340.010
compound eye pigmentationGO:0048072170.010
digestive tract morphogenesisGO:00485461270.010
immune system processGO:00023763470.010
circadian behaviorGO:0048512760.010
regulation of cholesterol transportGO:003237410.010
central nervous system developmentGO:00074172010.010
negative regulation of immune system processGO:0002683500.010
glandular epithelial cell differentiationGO:000206710.010

sisA disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.028
disease of metabolismDOID:001466700.019
nervous system diseaseDOID:86300.018
cardiovascular system diseaseDOID:128700.017
acquired metabolic diseaseDOID:006015800.016
inherited metabolic disorderDOID:65500.013
glucose metabolism diseaseDOID:419400.013
diabetes mellitusDOID:935100.013
carbohydrate metabolism diseaseDOID:005001300.013
musculoskeletal system diseaseDOID:1700.012
central nervous system diseaseDOID:33100.011