Drosophila melanogaster

55 known processes

Pi3K68D (Dmel_CG11621)

Phosphotidylinositol 3 kinase 68D

(Aliases: PI3K_68D,dPI3K,Cpk,cpk,CG11621,PI3K,PI3K-68D/E,PI3K 68_D,PI3K68D,PI3K-68D,dPIK,PI3K 68D,11621,BcDNA:LD15217,Dmel\CG11621,PI(3)K,PI[[3]]K,Pi3K)

Pi3K68D biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
embryonic morphogenesisGO:00485982060.721
Fly
actin filament based processGO:00300292200.577
cortical cytoskeleton organizationGO:0030865290.552
dorsal closureGO:0007391790.539
response to oxidative stressGO:0006979860.517
Fly
actin cytoskeleton organizationGO:00300362060.515
taxisGO:00423303040.456
Mouse
morphogenesis of embryonic epitheliumGO:0016331940.398
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.356
deathGO:00162652840.345
chemotaxisGO:00069352490.313
Mouse
nucleocytoplasmic transportGO:0006913720.286
morphogenesis of an epitheliumGO:00020092760.280
chaeta developmentGO:0022416970.270
cell motilityGO:00488702510.260
embryo development ending in birth or egg hatchingGO:00097921520.245
Fly
transcription from rna polymerase ii promoterGO:00063663680.225
regulation of notch signaling pathwayGO:00085931000.216
axon guidanceGO:00074112330.208
cell migrationGO:00164772380.208
regulation of vesicle mediated transportGO:0060627590.202
Worm
organic substance transportGO:00717022570.187
positive regulation of gene expressionGO:00106282900.186
Fly
tissue morphogenesisGO:00487292970.179
positive regulation of rna biosynthetic processGO:19026802660.177
appendage morphogenesisGO:00351073970.174
regulation of localizationGO:00328792750.172
Mouse Worm
establishment of protein localizationGO:00451841630.149
response to organic substanceGO:00100332840.148
small molecule metabolic processGO:00442813050.147
localization of cellGO:00516742570.147
developmental growthGO:00485892800.140
Fly
cellular catabolic processGO:00442483720.138
Fly
neuron projection guidanceGO:00974852410.137
cell cell signaling involved in cell fate commitmentGO:00451682100.130
protein complex assemblyGO:00064612000.130
negative regulation of cellular metabolic processGO:00313243820.129
Fly
chromatin modificationGO:00165681470.124
positive regulation of multicellular organismal processGO:00512401430.122
Fly
protein targetingGO:0006605640.120
positive regulation of cellular biosynthetic processGO:00313283160.119
Fly
regulation of transportGO:00510491810.118
Mouse Worm
regulation of multicellular organismal developmentGO:20000264140.117
Fly
positive regulation of transportGO:0051050920.115
Worm
intracellular protein transportGO:00068861040.114
histone modificationGO:00165701060.114
regulation of cellular ketone metabolic processGO:001056530.113
regulation of intracellular protein transportGO:0033157460.108
vesicle localizationGO:0051648550.107
chromosome organizationGO:00512763600.106
hematopoietic or lymphoid organ developmentGO:0048534570.102
epithelial cell differentiationGO:00308553220.101
forebrain developmentGO:003090020.100
positive regulation of developmental growthGO:0048639620.099
Fly
compound eye developmentGO:00487493070.098
peptidyl amino acid modificationGO:00181931050.097
wing disc morphogenesisGO:00074723440.095
chaeta morphogenesisGO:0008407420.094
body morphogenesisGO:001017120.093
endomembrane system organizationGO:00102561190.090
nucleobase containing small molecule metabolic processGO:00550861740.089
regionalizationGO:00030024160.088
positive regulation of defense responseGO:0031349590.085
striated muscle cell differentiationGO:0051146900.085
macromolecular complex assemblyGO:00650032560.083
regulation of mitotic cell cycleGO:00073461900.082
Fly
negative regulation of nervous system developmentGO:0051961920.082
protein complex biogenesisGO:00702712010.081
positive regulation of developmental processGO:00510941430.076
Fly
regulation of cellular localizationGO:00603411360.075
regulation of molecular functionGO:00650092170.075
central nervous system developmentGO:00074172010.072
cell deathGO:00082192790.072
larval developmentGO:00021641040.072
Worm Fly
regulation of erbb signaling pathwayGO:1901184420.072
Fly
single organism intracellular transportGO:19025822070.069
single organism membrane organizationGO:0044802930.068
phosphorylationGO:00163102940.066
regulation of sequence specific dna binding transcription factor activityGO:0051090120.065
female meiotic divisionGO:0007143700.065
vesicle mediated transportGO:00161923810.065
embryonic development via the syncytial blastodermGO:00017001480.064
Fly
negative regulation of cell deathGO:0060548810.064
axonogenesisGO:00074092900.064
cellular nitrogen compound catabolic processGO:00442701650.063
organonitrogen compound metabolic processGO:19015643180.063
negative regulation of nucleic acid templated transcriptionGO:19035072400.062
protein modification by small protein removalGO:0070646280.062
programmed cell deathGO:00125012570.061
muscle cell differentiationGO:00426921030.060
positive regulation of macromolecule metabolic processGO:00106044050.059
Fly
regulation of cell cycle phase transitionGO:19019871300.059
immune response regulating signaling pathwayGO:000276420.059
hemopoiesisGO:0030097460.057
single organism cellular localizationGO:19025801800.056
establishment of localization in cellGO:00516494020.056
regulation of endocytosisGO:0030100370.055
Worm
homeostatic processGO:00425921990.055
response to lipopolysaccharideGO:003249640.055
protein transportGO:00150311550.055
cellular amino acid metabolic processGO:0006520610.053
imaginal disc derived wing morphogenesisGO:00074763370.053
eye developmentGO:00016543230.052
positive regulation of cell motilityGO:200014730.051
extrinsic apoptotic signaling pathwayGO:009719110.050
regulation of secretion by cellGO:1903530390.050
molting cycleGO:0042303560.049
negative regulation of rna metabolic processGO:00512532510.048
negative regulation of cellular biosynthetic processGO:00313272770.048
positive regulation of exocytosisGO:004592140.048
regulation of immune effector processGO:0002697520.047
positive regulation of protein metabolic processGO:00512471280.047
Fly
positive regulation of signal transductionGO:00099672230.046
lipid metabolic processGO:00066291210.046
germ band shorteningGO:0007390190.045
Fly
regulation of cytoplasmic transportGO:1903649470.044
organic cyclic compound catabolic processGO:19013611680.043
muscle structure developmentGO:00610612240.043
response to extracellular stimulusGO:00099911160.043
Fly
cortical actin cytoskeleton organizationGO:0030866240.042
organic substance catabolic processGO:19015753080.042
positive regulation of cell developmentGO:0010720610.042
protein dna complex subunit organizationGO:0071824860.042
regulation of i kappab kinase nf kappab signalingGO:004312220.042
locomotory behaviorGO:00076261760.042
protein importGO:0017038550.040
cell proliferationGO:00082832990.040
Fly
regulation of cell cycleGO:00517262910.040
Fly
regulation of microtubule based processGO:0032886490.040
regulation of cellular component biogenesisGO:00440872010.040
immune response activating signal transductionGO:000275720.040
cellular response to organic substanceGO:00713101320.039
notch signaling pathwayGO:00072191200.039
regulation of epidermal growth factor receptor signaling pathwayGO:0042058420.039
Fly
muscle organ developmentGO:00075171270.038
macromolecule catabolic processGO:00090571610.038
intracellular transportGO:00469072280.038
sensory organ morphogenesisGO:00905962600.038
multicellular organism growthGO:0035264460.037
Fly
epithelial cell developmentGO:00020642740.036
carbohydrate metabolic processGO:0005975820.036
Fly
regulation of transcription from rna polymerase ii promoterGO:00063573780.036
regulation of intracellular transportGO:0032386640.036
positive regulation of nervous system developmentGO:0051962690.036
membrane organizationGO:00610241120.036
Worm
posttranscriptional regulation of gene expressionGO:00106081450.035
Fly
response to ethanolGO:0045471590.035
divalent inorganic cation transportGO:0072511300.035
cellular response to chemical stimulusGO:00708871990.035
negative regulation of gene expressionGO:00106293870.035
regulation of cellular component movementGO:0051270420.034
appendage developmentGO:00487364010.034
photoreceptor cell developmentGO:0042461960.034
protein targeting to nucleusGO:0044744510.033
positive regulation of transcription dna templatedGO:00458932660.033
positive regulation of response to stimulusGO:00485843230.033
regulation of developmental growthGO:00486381740.033
Fly
neurological system processGO:00508773580.033
nuclear transportGO:0051169720.033
negative regulation of biosynthetic processGO:00098902770.033
meiotic cell cycle processGO:19030461320.032
positive regulation of rna metabolic processGO:00512542710.032
regulation of protein transportGO:0051223570.032
protein phosphorylationGO:00064681690.032
synaptic transmissionGO:00072682880.032
Fly
positive regulation of cellular component biogenesisGO:0044089800.032
fertilizationGO:0009566260.032
chemical homeostasisGO:0048878920.031
posttranscriptional gene silencing by rnaGO:0035194450.031
apoptotic processGO:00069151590.031
single organism nuclear importGO:1902593510.031
response to starvationGO:0042594970.031
Fly
positive regulation of signalingGO:00230562430.031
cellular ketone metabolic processGO:0042180240.031
response to oxygen containing compoundGO:19017002000.030
regulation of neuron differentiationGO:00456641030.030
Fly
meiotic cell cycleGO:00513211710.030
endocytosisGO:00068973100.030
regulation of apoptotic processGO:00429811300.030
exocytosisGO:0006887280.030
imaginal disc derived appendage developmentGO:00487373990.030
negative regulation of signal transductionGO:00099682060.030
Fly
regulation of neurogenesisGO:00507671580.030
Fly
cell adhesionGO:00071551360.029
regulation of gene expression epigeneticGO:00400291280.029
connective tissue developmentGO:006144830.029
smoothened signaling pathwayGO:0007224490.029
negative regulation of transcription dna templatedGO:00458922370.029
positive regulation of biosynthetic processGO:00098913160.029
Fly
response to organic cyclic compoundGO:0014070890.028
regulation of protein import into nucleusGO:0042306280.028
regulation of programmed cell deathGO:00430671520.028
regulation of cellular amine metabolic processGO:003323830.028
regulation of transmembrane transportGO:0034762270.027
Mouse
positive regulation of growthGO:0045927750.027
Fly
establishment or maintenance of cell polarityGO:00071631670.027
dna templated transcription elongationGO:0006354180.027
positive regulation of cell migrationGO:003033520.027
positive regulation of cell differentiationGO:0045597640.027
purine containing compound metabolic processGO:00725211550.027
positive regulation of cell deathGO:0010942690.027
negative regulation of notch signaling pathwayGO:0045746410.027
behavioral response to ethanolGO:0048149490.027
positive regulation of molecular functionGO:00440931360.027
cytoplasmic transportGO:00164821300.027
ribonucleotide catabolic processGO:00092611090.026
muscle system processGO:0003012210.026
phagocytosisGO:00069092150.026
regulation of catabolic processGO:00098941700.026
Fly
negative regulation of nucleobase containing compound metabolic processGO:00459342610.026
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.025
protein localization to nucleusGO:0034504550.025
head involutionGO:0008258350.025
regulation of cellular amino acid metabolic processGO:000652100.025
regulation of nervous system developmentGO:00519602480.025
Fly
cellular homeostasisGO:0019725800.024
neuromuscular junction developmentGO:00075281490.024
Fly
ubiquitin dependent protein catabolic processGO:0006511780.024
purine ribonucleotide catabolic processGO:00091541090.024
chromatin organizationGO:00063252070.024
protein modification processGO:00362114380.024
positive regulation of nucleic acid templated transcriptionGO:19035082660.024
immune system developmentGO:0002520570.023
post embryonic appendage morphogenesisGO:00351203850.023
apoptotic cell clearanceGO:0043277140.023
Worm
nucleoside triphosphate catabolic processGO:00091431080.023
negative regulation of cell communicationGO:00106482230.023
Fly
chemosensory behaviorGO:00076351060.023
meiotic nuclear divisionGO:00071261510.023
positive regulation of catabolic processGO:00098961050.022
gene silencingGO:00164581380.022
negative regulation of response to stimulusGO:00485852580.022
Fly
regulation of synapse structure and activityGO:00508031280.022
Fly
regulation of protein localizationGO:0032880760.022
regulation of growthGO:00400082330.022
Fly
positive regulation of sequence specific dna binding transcription factor activityGO:005109190.022
negative regulation of apoptotic processGO:0043066630.022
protein deubiquitinationGO:0016579170.022
regulation of response to external stimulusGO:00321011150.022
regulation of epithelial cell differentiationGO:003085640.021
muscle cell developmentGO:0055001500.021
golgi organizationGO:0007030660.021
lateral inhibitionGO:00463312060.021
dna metabolic processGO:00062592270.021
purine containing compound catabolic processGO:00725231120.021
regulation of nucleocytoplasmic transportGO:0046822350.021
positive regulation of intracellular transportGO:0032388420.021
positive regulation of nitrogen compound metabolic processGO:00511733540.021
positive regulation of nucleobase containing compound metabolic processGO:00459353320.021
response to light stimulusGO:00094161240.021
secretion by cellGO:00329401010.021
metal ion transportGO:0030001740.020
Mouse
organonitrogen compound biosynthetic processGO:19015661170.020
regulation of mitotic cell cycle phase transitionGO:19019901300.020
purine ribonucleotide metabolic processGO:00091501450.020
regulation of cell developmentGO:00602842150.020
Fly
telencephalon developmentGO:002153720.020
sex differentiationGO:0007548810.019
regulation of cell deathGO:00109411730.019
mitotic cell cycle phase transitionGO:00447721380.019
modification dependent macromolecule catabolic processGO:0043632790.019
gene silencing by rnaGO:0031047570.019
protein modification by small protein conjugation or removalGO:00706471060.019
single organism catabolic processGO:00447122280.019
regulation of dna templated transcription elongationGO:0032784170.019
regulation of multicellular organism growthGO:0040014400.019
Fly
positive regulation of programmed cell deathGO:0043068620.019
regulation of phosphorus metabolic processGO:00511742100.019
erbb signaling pathwayGO:0038127580.019
Fly
response to nutrient levelsGO:00316671140.018
Fly
response to woundingGO:0009611940.018
synapse assemblyGO:00074161430.018
Fly
purine nucleoside catabolic processGO:00061521120.018
nuclear importGO:0051170510.018
response to endogenous stimulusGO:00097191190.018
cell cycle phase transitionGO:00447701400.018
regulation of cell proliferationGO:00421271630.018
Fly
axon developmentGO:00615642970.018
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.018
Fly
regulation of cell cycle processGO:00105641810.018
cellular component assembly involved in morphogenesisGO:00109271510.018
compound eye morphogenesisGO:00017452490.018
carboxylic acid metabolic processGO:0019752920.017
proteolysisGO:00065081920.017
covalent chromatin modificationGO:00165691060.017
imaginal disc derived wing vein specificationGO:0007474480.017
sevenless signaling pathwayGO:004550040.017
protein localizationGO:00081042840.017
peptidyl threonine phosphorylationGO:001810720.017
regulation of secretionGO:0051046440.017
gonad developmentGO:0008406500.017
purine nucleotide catabolic processGO:00061951090.017
proteolysis involved in cellular protein catabolic processGO:0051603830.017
regulation of synapse assemblyGO:0051963940.017
positive regulation of secretionGO:0051047220.016
negative regulation of nitrogen compound metabolic processGO:00511722650.016
modification dependent protein catabolic processGO:0019941780.016
negative regulation of molecular functionGO:0044092510.016
cellular amine metabolic processGO:0044106120.016
regulation of reproductive processGO:2000241540.016
negative regulation of cell cycle phase transitionGO:19019881030.016
regulation of response to stressGO:00801342000.016
reproductive structure developmentGO:0048608740.016
positive regulation of cellular component organizationGO:00511301560.016
Worm
skeletal muscle organ developmentGO:0060538480.016
cytokinesisGO:0000910900.016
protein import into nucleusGO:0006606510.016
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.016
synapse organizationGO:00508081960.016
Fly
single organism biosynthetic processGO:00447112060.016
response to lipidGO:0033993380.016
regulation of microtubule cytoskeleton organizationGO:0070507410.015
response to peptide hormoneGO:0043434290.015
regulation of hemocyte proliferationGO:0035206370.015
response to organonitrogen compoundGO:0010243750.015
nucleoside phosphate metabolic processGO:00067531620.015
negative regulation of macromolecule biosynthetic processGO:00105582700.015
positive regulation of response to external stimulusGO:0032103440.015
single organismal cell cell adhesionGO:0016337450.015
endosomal transportGO:0016197440.015
negative regulation of growthGO:0045926840.015
regulation of nf kappab import into nucleusGO:004234510.015
positive regulation of cell communicationGO:00106472500.015
regulation of phosphate metabolic processGO:00192202100.014
carbohydrate derivative metabolic processGO:19011352170.014
negative regulation of sequence specific dna binding transcription factor activityGO:004343340.014
divalent metal ion transportGO:0070838260.014
limb morphogenesisGO:003510810.014
regulation of cell motilityGO:2000145230.014
regulation of neuron projection developmentGO:0010975690.014
Fly
oxoacid metabolic processGO:00434361030.014
camp metabolic processGO:0046058190.014
nucleoside catabolic processGO:00091641120.014
cellular macromolecule localizationGO:00707272200.014
eye morphogenesisGO:00485922600.014
positive regulation of neurogenesisGO:0050769410.014
signal transduction by phosphorylationGO:00230141070.014
cellular protein modification processGO:00064644380.014
ameboidal type cell migrationGO:00016671510.014
ribose phosphate metabolic processGO:00196931450.014
glycosyl compound metabolic processGO:19016571270.013
intracellular signal transductionGO:00355563000.013
Mouse
positive regulation of cellular amino acid metabolic processGO:004576400.013
synaptic vesicle transportGO:0048489500.013
amine metabolic processGO:0009308120.013
early endosome to late endosome transportGO:004502230.013
instar larval developmentGO:0002168550.013
Fly
anterior posterior pattern specificationGO:00099521360.013
cell growthGO:00160491080.013
aromatic compound catabolic processGO:00194391660.013
regulation of response to woundingGO:1903034190.013
protein autophosphorylationGO:0046777150.013
positive regulation of cell cycle processGO:0090068280.013
inositol lipid mediated signalingGO:004801740.013
positive regulation of multi organism processGO:0043902400.012
endoplasmic reticulum organizationGO:0007029130.012
response to growth factorGO:0070848310.012
negative regulation of multicellular organismal processGO:00512411420.012
regulation of autophagyGO:0010506620.012
Fly
purine ribonucleoside metabolic processGO:00461281270.012
imaginal disc derived appendage morphogenesisGO:00351143950.012
regulation of catalytic activityGO:00507901850.012
purine nucleoside metabolic processGO:00422781270.012
growthGO:00400073590.012
Fly
nucleotide metabolic processGO:00091171610.012
regulation of protein modification processGO:00313991120.012
anatomical structure homeostasisGO:0060249970.012
positive regulation of neuron apoptotic processGO:004352510.012
ribonucleotide metabolic processGO:00092591450.012
negative regulation of cellular component organizationGO:00511291080.012
single organism cell adhesionGO:0098602470.012
lipid biosynthetic processGO:0008610460.012
positive regulation of endocytosisGO:0045807220.012
Worm
cellular response to growth factor stimulusGO:0071363300.012
receptor mediated endocytosisGO:0006898210.012
cellular macromolecular complex assemblyGO:00346221530.012
negative regulation of developmental growthGO:0048640640.011
positive regulation of mitotic cell cycleGO:0045931340.011
cellular lipid metabolic processGO:0044255830.011
cellular response to starvationGO:0009267610.011
Fly
regulation of cell differentiationGO:00455953020.011
Fly
reproductive system developmentGO:0061458740.011
chromosome segregationGO:00070591570.011
heterocycle catabolic processGO:00467001660.011
negative regulation of secretion by cellGO:190353140.011
regulation of immune system processGO:00026821760.011
detection of stimulusGO:00516061560.011
cellular cation homeostasisGO:0030003380.011
positive regulation of immune responseGO:0050778630.011
mesenchymal cell developmentGO:001403110.011
ion transportGO:00068111450.011
Mouse
regulation of cell substrate adhesionGO:001081020.011
actin filament organizationGO:00070151260.011
rna processingGO:00063961470.011
nf kappab import into nucleusGO:004234810.011
epithelium migrationGO:00901321480.011
cation transmembrane transportGO:0098655880.011
Mouse
cellular response to endogenous stimulusGO:0071495800.011
positive regulation of protein transportGO:0051222370.011
negative regulation of developmental processGO:00510932010.011
nucleoside triphosphate metabolic processGO:00091411200.010
negative regulation of catalytic activityGO:0043086420.010
enzyme linked receptor protein signaling pathwayGO:00071671790.010
Fly
spermatid developmentGO:0007286980.010
positive regulation of phosphate metabolic processGO:00459371390.010
regulation of cellular protein catabolic processGO:1903362440.010
negative regulation of growth of symbiont involved in interaction with hostGO:004414690.010
morphogenesis of a polarized epitheliumGO:0001738930.010
regulation of cellular response to growth factor stimulusGO:0090287130.010
regulation of embryonic developmentGO:0045995680.010
myotube differentiationGO:0014902460.010
cellular protein localizationGO:00346131600.010
regulation of smoothened signaling pathwayGO:0008589280.010
ovarian follicle cell migrationGO:00072971210.010
nucleoside phosphate biosynthetic processGO:1901293340.010

Pi3K68D disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.066
disease of cellular proliferationDOID:1456600.018
organ system cancerDOID:005068600.013
cancerDOID:16200.013