Drosophila melanogaster

148 known processes

step (Dmel_CG11628)

steppke

(Aliases: cytohesin/GRP1,GPH,l(2)k08110,l(2)SH0323,CG11633,stepk,CG11628,GRP1/cytohesin 1,l(2)SH2 0323,Grp1,GRP1,CYH1,Dmel\CG11628)

step biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
phosphorylationGO:00163102940.784
regulation of synaptic growth at neuromuscular junctionGO:0008582890.752
neuromuscular junction developmentGO:00075281490.751
tissue morphogenesisGO:00487292970.718
negative regulation of cell communicationGO:00106482230.707
synapse organizationGO:00508081960.628
regulation of growthGO:00400082330.610
regulation of developmental growthGO:00486381740.534
protein phosphorylationGO:00064681690.430
growthGO:00400073590.425
synaptic growth at neuromuscular junctionGO:00511241190.390
intracellular signal transductionGO:00355563000.350
negative regulation of signal transductionGO:00099682060.322
imaginal disc derived appendage developmentGO:00487373990.310
morphogenesis of an epitheliumGO:00020092760.306
intracellular transportGO:00469072280.274
Human
organic substance catabolic processGO:19015753080.271
Human Mouse
chemical homeostasisGO:0048878920.250
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.243
post embryonic appendage morphogenesisGO:00351203850.238
autophagyGO:00069141080.233
regionalizationGO:00030024160.232
regulation of synapse structure and activityGO:00508031280.225
imaginal disc derived appendage morphogenesisGO:00351143950.224
actin cytoskeleton organizationGO:00300362060.218
cellular protein catabolic processGO:0044257830.214
macromolecule catabolic processGO:00090571610.212
negative regulation of response to stimulusGO:00485852580.212
regulation of cellular component biogenesisGO:00440872010.210
proteolysis involved in cellular protein catabolic processGO:0051603830.209
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.186
regulation of cellular amino acid metabolic processGO:000652100.183
cation transportGO:00068121100.179
regulation of catabolic processGO:00098941700.175
Human Mouse
regulation of notch signaling pathwayGO:00085931000.175
gland developmentGO:00487321910.170
multicellular organism growthGO:0035264460.167
negative regulation of signalingGO:00230572190.164
salivary gland morphogenesisGO:00074351450.163
appendage developmentGO:00487364010.162
regulation of lipid metabolic processGO:0019216150.161
gland morphogenesisGO:00226121450.160
modification dependent protein catabolic processGO:0019941780.157
positive regulation of signalingGO:00230562430.155
programmed cell deathGO:00125012570.154
modification dependent macromolecule catabolic processGO:0043632790.153
embryonic development via the syncytial blastodermGO:00017001480.149
ubiquitin dependent protein catabolic processGO:0006511780.146
inositol lipid mediated signalingGO:004801740.142
positive regulation of developmental growthGO:0048639620.141
positive regulation of synaptic growth at neuromuscular junctionGO:0045887260.138
imaginal disc derived wing morphogenesisGO:00074763370.133
deathGO:00162652840.133
regulation of nervous system developmentGO:00519602480.133
carbohydrate derivative metabolic processGO:19011352170.129
Human Mouse
cellular catabolic processGO:00442483720.129
Human Mouse
regulation of intracellular signal transductionGO:19025312360.125
nucleobase containing compound catabolic processGO:00346551650.124
Human Mouse
regulation of cellular ketone metabolic processGO:001056530.123
protein modification processGO:00362114380.122
regulation of multicellular organism growthGO:0040014400.121
tor signalingGO:0031929320.118
regulation of multicellular organismal developmentGO:20000264140.116
synapse assemblyGO:00074161430.115
purine nucleoside triphosphate metabolic processGO:00091441190.114
Human Mouse
localization of cellGO:00516742570.111
aromatic compound catabolic processGO:00194391660.110
Human Mouse
nucleoside triphosphate metabolic processGO:00091411200.109
Human Mouse
regulation of cell deathGO:00109411730.107
phosphatidylinositol mediated signalingGO:004801540.106
regulation of cellular localizationGO:00603411360.106
proteolysisGO:00065081920.106
response to radiationGO:00093141550.104
establishment of localization in cellGO:00516494020.104
Human
positive regulation of cell communicationGO:00106472500.102
positive regulation of cellular component biogenesisGO:0044089800.101
single organism biosynthetic processGO:00447112060.100
erbb signaling pathwayGO:0038127580.098
embryonic morphogenesisGO:00485982060.096
macroautophagyGO:0016236420.096
actin filament based processGO:00300292200.093
wing disc morphogenesisGO:00074723440.093
regulation of programmed cell deathGO:00430671520.091
catabolic processGO:00090564090.089
Human Mouse
organelle fusionGO:0048284460.089
single organism intracellular transportGO:19025822070.088
Human
cell deathGO:00082192790.086
nitrogen compound transportGO:0071705850.086
appendage morphogenesisGO:00351073970.084
regulation of proteolysisGO:0030162870.083
lipid biosynthetic processGO:0008610460.083
regulation of epidermal growth factor receptor signaling pathwayGO:0042058420.083
negative regulation of autophagyGO:0010507160.082
determination of adult lifespanGO:00083401370.081
peptidyl threonine phosphorylationGO:001810720.080
protein catabolic processGO:00301631010.080
regulation of cell cycle processGO:00105641810.079
actin filament organizationGO:00070151260.079
cell motilityGO:00488702510.077
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.076
developmental growthGO:00485892800.075
negative regulation of synaptic growth at neuromuscular junctionGO:0045886390.075
autophagic cell deathGO:0048102830.075
nucleotide metabolic processGO:00091171610.074
Human Mouse
nucleoside metabolic processGO:00091161270.074
Human Mouse
response to organic substanceGO:00100332840.072
exocrine system developmentGO:00352721620.067
negative regulation of fibroblast growth factor receptor signaling pathwayGO:004003720.067
leg disc developmentGO:0035218920.065
regulation of apoptotic processGO:00429811300.065
negative regulation of multicellular organismal processGO:00512411420.062
positive regulation of phosphate metabolic processGO:00459371390.062
notch signaling pathwayGO:00072191200.061
single organism catabolic processGO:00447122280.061
Human Mouse
lipid metabolic processGO:00066291210.060
multicellular organismal agingGO:00102591400.059
body morphogenesisGO:001017120.059
regulation of localizationGO:00328792750.056
cellular ketone metabolic processGO:0042180240.056
response to abiotic stimulusGO:00096283410.055
forebrain developmentGO:003090020.055
positive regulation of cellular protein metabolic processGO:00322701180.055
organonitrogen compound metabolic processGO:19015643180.054
Human Mouse
phosphatidylinositol 3 kinase signalingGO:001406540.054
negative regulation of cellular metabolic processGO:00313243820.054
negative regulation of cell deathGO:0060548810.053
negative regulation of synapse assemblyGO:0051964390.052
male gamete generationGO:00482322010.052
regulation of phosphorus metabolic processGO:00511742100.052
cell migrationGO:00164772380.052
cell cycle checkpointGO:0000075950.051
intracellular protein transportGO:00068861040.051
organic substance transportGO:00717022570.051
secretion by cellGO:00329401010.050
cellular response to nutrient levelsGO:0031669620.050
positive regulation of phosphorylationGO:0042327870.048
regulation of transportGO:00510491810.048
regulation of phosphate metabolic processGO:00192202100.047
cellular protein modification processGO:00064644380.047
regulation of protein metabolic processGO:00512462560.046
cellular macromolecule catabolic processGO:00442651360.046
mapk cascadeGO:00001651070.046
central nervous system developmentGO:00074172010.046
organelle assemblyGO:00709251980.046
cellular response to insulin stimulusGO:0032869280.046
instar larval developmentGO:0002168550.045
ion transmembrane transportGO:00342201220.044
positive regulation of nitrogen compound metabolic processGO:00511733540.044
Human Mouse
regulation of locomotionGO:0040012420.043
synaptic transmissionGO:00072682880.043
regulation of cell cycleGO:00517262910.043
epidermal growth factor receptor signaling pathwayGO:0007173580.042
apoptotic processGO:00069151590.041
regulation of synapse organizationGO:00508071100.041
salivary gland developmentGO:00074311620.041
regulation of vesicle mediated transportGO:0060627590.041
negative regulation of phosphorylationGO:0042326350.040
cellular amino acid metabolic processGO:0006520610.040
regulation of cell developmentGO:00602842150.040
regulation of synaptic transmissionGO:0050804690.039
regulation of phosphorylationGO:00423251470.038
cation transmembrane transportGO:0098655880.038
immune effector processGO:0002252980.038
chorion containing eggshell formationGO:00073041050.038
establishment of tissue polarityGO:0007164870.038
calcium ion transportGO:0006816240.037
regulation of cellular amine metabolic processGO:003323830.037
enzyme linked receptor protein signaling pathwayGO:00071671790.037
larval developmentGO:00021641040.036
mitotic spindle organizationGO:00070522200.035
cognitionGO:00508901410.035
organic cyclic compound catabolic processGO:19013611680.035
Human Mouse
extrinsic apoptotic signaling pathwayGO:009719110.034
purine containing compound catabolic processGO:00725231120.034
Human Mouse
protein modification by small protein conjugationGO:0032446790.034
purine ribonucleoside catabolic processGO:00461301120.034
Human Mouse
ribonucleoside metabolic processGO:00091191270.034
Human Mouse
heterocycle catabolic processGO:00467001660.033
Human Mouse
protein localizationGO:00081042840.033
nucleoside phosphate catabolic processGO:19012921100.033
Human Mouse
cell cycle phase transitionGO:00447701400.033
proteasomal protein catabolic processGO:0010498590.033
actin filament polymerizationGO:0030041270.033
positive regulation of cellular component organizationGO:00511301560.033
oxoacid metabolic processGO:00434361030.032
cellular lipid metabolic processGO:0044255830.032
spinal cord patterningGO:002151110.031
anterior posterior axis specificationGO:00099481090.031
ribonucleoside triphosphate metabolic processGO:00091991190.031
Human Mouse
nuclear divisionGO:00002803320.031
regulation of response to external stimulusGO:00321011150.031
spermatogenesisGO:00072832000.030
regulation of cell migrationGO:0030334220.030
positive regulation of secretionGO:0051047220.030
epithelial cell differentiationGO:00308553220.030
regulation of actin filament lengthGO:0030832270.030
positive regulation of tor signalingGO:0032008130.030
cellular amine metabolic processGO:0044106120.030
secretionGO:00469031090.029
salivary gland cell autophagic cell deathGO:0035071830.029
neurological system processGO:00508773580.029
positive regulation of signal transductionGO:00099672230.029
segmentationGO:00352822070.029
regulation of purine nucleotide metabolic processGO:1900542620.029
Human Mouse
neuron recognitionGO:00080381010.029
heart contractionGO:0060047260.029
ribose phosphate metabolic processGO:00196931450.029
Human Mouse
phagocytosisGO:00069092150.028
regulation of protein catabolic processGO:0042176550.028
regulation of cellular catabolic processGO:00313291570.028
Human Mouse
nucleoside triphosphate catabolic processGO:00091431080.028
Human Mouse
positive regulation of phosphorus metabolic processGO:00105621390.027
embryo development ending in birth or egg hatchingGO:00097921520.027
glycosyl compound metabolic processGO:19016571270.027
Human Mouse
amine metabolic processGO:0009308120.027
purine ribonucleotide catabolic processGO:00091541090.026
Human Mouse
regulation of cell growthGO:0001558430.026
regulation of protein modification processGO:00313991120.026
salivary gland histolysisGO:0035070880.026
regulation of tor signalingGO:0032006210.026
blastoderm segmentationGO:00073501590.025
negative regulation of erbb signaling pathwayGO:1901185290.025
regulation of synapse assemblyGO:0051963940.025
regulation of actin polymerization or depolymerizationGO:0008064270.025
cell adhesionGO:00071551360.024
Human Mouse
regulation of embryonic developmentGO:0045995680.024
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.024
positive regulation of macromolecule metabolic processGO:00106044050.024
positive regulation of catabolic processGO:00098961050.024
Human Mouse
homeostatic processGO:00425921990.024
epithelial cell developmentGO:00020642740.023
regulation of protein localizationGO:0032880760.023
regulation of anatomical structure morphogenesisGO:00226032420.023
dna catabolic processGO:0006308160.023
imaginal disc derived leg morphogenesisGO:0007480800.023
positive regulation of protein metabolic processGO:00512471280.023
peptidyl threonine modificationGO:001821030.022
cytoplasmic transportGO:00164821300.022
regulation of wound healingGO:0061041130.022
regulation of neurogenesisGO:00507671580.022
digestive tract developmentGO:00485651490.022
establishment of protein localizationGO:00451841630.022
germarium derived egg chamber formationGO:00072931010.022
eye developmentGO:00016543230.022
regulation of autophagyGO:0010506620.022
biological adhesionGO:00226101380.021
Human Mouse
carboxylic acid metabolic processGO:0019752920.021
inorganic cation transmembrane transportGO:0098662610.021
regulation of cellular protein metabolic processGO:00322682430.021
regulation of cell cycle phase transitionGO:19019871300.021
negative regulation of cellular component organizationGO:00511291080.021
regulation of protein phosphorylationGO:0001932640.021
cellular chemical homeostasisGO:0055082400.021
positive regulation of developmental processGO:00510941430.021
neuron apoptotic processGO:0051402170.021
establishment or maintenance of cytoskeleton polarityGO:0030952440.021
regulation of cellular component sizeGO:0032535980.021
positive regulation of nucleotide metabolic processGO:0045981550.021
Human Mouse
hemopoiesisGO:0030097460.021
spermatid developmentGO:0007286980.020
regulation of response to nutrient levelsGO:0032107180.020
regulation of proteasomal protein catabolic processGO:0061136390.020
locomotory behaviorGO:00076261760.020
positive regulation of cell migrationGO:003033520.020
positive regulation of cell deathGO:0010942690.020
positive regulation of intracellular signal transductionGO:19025331160.020
organophosphate biosynthetic processGO:0090407460.020
metal ion homeostasisGO:0055065440.020
regulation of response to stressGO:00801342000.020
nucleoside catabolic processGO:00091641120.020
Human Mouse
negative regulation of phosphorus metabolic processGO:0010563450.020
positive regulation of molecular functionGO:00440931360.020
regulation of cellular component movementGO:0051270420.020
ribonucleoside triphosphate catabolic processGO:00092031080.019
Human Mouse
signal transduction by phosphorylationGO:00230141070.019
response to insulinGO:0032868290.019
protein ubiquitinationGO:0016567700.019
regulation of mitotic cell cycle phase transitionGO:19019901300.019
response to woundingGO:0009611940.019
stress activated protein kinase signaling cascadeGO:0031098550.019
regulation of anatomical structure sizeGO:00900661630.018
response to oxygen containing compoundGO:19017002000.018
epidermis developmentGO:0008544650.018
positive regulation of protein catabolic processGO:0045732340.018
purine nucleoside metabolic processGO:00422781270.018
Human Mouse
positive regulation of multicellular organism growthGO:0040018210.018
regulation of peptidyl tyrosine phosphorylationGO:0050730100.018
mitotic sister chromatid segregationGO:0000070870.018
protein complex assemblyGO:00064612000.018
purine ribonucleoside triphosphate catabolic processGO:00092071080.018
Human Mouse
border follicle cell migrationGO:00072981130.018
tissue migrationGO:00901301550.017
larval behaviorGO:0030537420.017
cell growthGO:00160491080.017
regulation of catalytic activityGO:00507901850.017
metal ion transportGO:0030001740.017
negative regulation of programmed cell deathGO:0043069720.017
ras protein signal transductionGO:0007265880.017
regulation of actin filament polymerizationGO:0030833250.017
regulation of small gtpase mediated signal transductionGO:0051056930.016
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052240.016
monovalent inorganic cation transportGO:0015672400.016
peripheral nervous system developmentGO:0007422520.016
cellular response to organic substanceGO:00713101320.016
cation homeostasisGO:0055080510.016
negative regulation of protein metabolic processGO:0051248850.015
negative regulation of catabolic processGO:0009895360.015
convergent extension involved in gastrulationGO:006002720.015
regulation of gtpase activityGO:0043087440.015
Human Mouse
purine nucleotide metabolic processGO:00061631460.015
Human Mouse
nuclear exportGO:0051168240.015
nuclear transportGO:0051169720.015
agingGO:00075681430.015
digestive tract morphogenesisGO:00485461270.015
negative regulation of cellular protein metabolic processGO:0032269850.015
regulation of cellular protein catabolic processGO:1903362440.015
protein transportGO:00150311550.015
negative regulation of protein phosphorylationGO:0001933170.015
induction of programmed cell deathGO:0012502120.015
cellular response to peptide hormone stimulusGO:0071375280.015
negative regulation of epidermal growth factor receptor signaling pathwayGO:0042059290.015
gliogenesisGO:0042063800.015
positive regulation of growthGO:0045927750.015
protein kinase b signalingGO:004349110.014
sister chromatid segregationGO:0000819920.014
endocytosisGO:00068973100.014
cellular metal ion homeostasisGO:0006875310.014
associative learningGO:0008306650.014
regulation of erbb signaling pathwayGO:1901184420.014
imaginal disc fusionGO:0046528190.014
establishment or maintenance of cell polarityGO:00071631670.014
Mouse
inorganic ion transmembrane transportGO:0098660730.013
autophagic vacuole assemblyGO:000004520.013
ion homeostasisGO:0050801550.013
positive regulation of transportGO:0051050920.013
regulation of cell proliferationGO:00421271630.013
response to organonitrogen compoundGO:0010243750.013
cellular nitrogen compound catabolic processGO:00442701650.013
Human Mouse
response to ecdysoneGO:0035075340.013
photoreceptor cell developmentGO:0042461960.013
negative regulation of phosphate metabolic processGO:0045936450.013
regulation of phosphatidylinositol 3 kinase activityGO:004355120.013
learning or memoryGO:00076111410.013
learningGO:0007612750.012
response to osmotic stressGO:0006970140.012
histolysisGO:00075591020.012
negative regulation of notch signaling pathwayGO:0045746410.012
morphogenesis of a polarized epitheliumGO:0001738930.012
hematopoietic progenitor cell differentiationGO:000224410.012
cell recognitionGO:00080371020.012
negative regulation of intracellular signal transductionGO:1902532570.012
skeletal muscle fiber developmentGO:004874130.012
positive regulation of response to stimulusGO:00485843230.012
cell maturationGO:00484691440.012
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436190.012
organophosphate metabolic processGO:00196371950.012
Human Mouse
purine nucleotide catabolic processGO:00061951090.012
Human Mouse
positive regulation of lipid metabolic processGO:004583440.012
mitotic cell cycle phase transitionGO:00447721380.012
regulation of establishment of protein localizationGO:0070201610.012
regulation of erk1 and erk2 cascadeGO:0070372390.012
regulation of macroautophagyGO:0016241150.012
regulation of endocytosisGO:0030100370.012
actin polymerization or depolymerizationGO:0008154310.012
response to extracellular stimulusGO:00099911160.012
negative regulation of developmental processGO:00510932010.011
cellular cation homeostasisGO:0030003380.011
purine ribonucleoside triphosphate metabolic processGO:00092051190.011
Human Mouse
ovarian follicle cell developmentGO:00307072480.011
positive regulation of cell developmentGO:0010720610.011
protein complex localizationGO:003150340.011
positive regulation of hydrolase activityGO:0051345780.011
Human Mouse
regulation of stress activated protein kinase signaling cascadeGO:0070302420.011
regulation of stress activated mapk cascadeGO:0032872410.011
positive regulation of cellular protein catabolic processGO:1903364240.011
mrna metabolic processGO:00160711240.011
multicellular organismal reproductive behaviorGO:00330571100.011
regulation of purine nucleotide catabolic processGO:0033121480.011
Human Mouse
brain developmentGO:00074201200.011
gtp metabolic processGO:0046039720.010
Human Mouse
establishment of organelle localizationGO:00516561220.010
regulation of phosphatase activityGO:001092130.010
tissue deathGO:00162711020.010
protein modification by small protein conjugation or removalGO:00706471060.010
ribonucleoside catabolic processGO:00424541120.010
Human Mouse
purine containing compound metabolic processGO:00725211550.010
Human Mouse
wound healingGO:0042060750.010
response to nutrient levelsGO:00316671140.010
cell fate determinationGO:0001709910.010

step disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org