IMP: Integrative Multi-species Prediction

Drosophila melanogaster

89 known processes

pUf68 (Dmel_CG12085)

poly U binding factor 68kD

(Aliases: Fir,hfp,Dmel\CG12085,anon-WO0118547.408,HFP,CG12085,Puf60,PUF60,dFIR,DPUF68,Hfp,pUbsf)

Entrez: 38173
FLYBASE: FBgn0028577
UniProtKB: A4V193
UniProtKB: Q8T6B9

Process Predictions
Disease Predictions

pUf68 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
rna splicing	GO:0008380	83	0.999
cell division	GO:0051301	248	0.992
meiotic nuclear division	GO:0007126	151	0.982	Worm
organelle fission	GO:0048285	340	0.981	Worm
regulation of rna splicing	GO:0043484	69	0.981
nuclear division	GO:0000280	332	0.954	Worm
mrna splicing via spliceosome	GO:0000398	73	0.937
rna splicing via transesterification reactions with bulged adenosine as nucleophile	GO:0000377	73	0.920
regulation of mrna splicing via spliceosome	GO:0048024	64	0.912
germarium derived egg chamber formation	GO:0007293	101	0.863
regulation of alternative mrna splicing via spliceosome	GO:0000381	60	0.830
meiotic cell cycle	GO:0051321	171	0.797	Worm
rna splicing via transesterification reactions	GO:0000375	73	0.781
growth	GO:0040007	359	0.736
reproductive structure development	GO:0048608	74	0.701	Worm
male meiosis	GO:0007140	52	0.662
taxis	GO:0042330	304	0.662	Worm
organelle localization	GO:0051640	148	0.658
regulation of nuclear division	GO:0051783	58	0.615	Worm
cytokinesis	GO:0000910	90	0.597
negative regulation of cellular biosynthetic process	GO:0031327	277	0.583
regulation of growth	GO:0040008	233	0.569
phosphorylation	GO:0016310	294	0.548
appendage development	GO:0048736	401	0.506
rna processing	GO:0006396	147	0.453
mrna processing	GO:0006397	104	0.450
regulation of mrna metabolic process	GO:1903311	72	0.437
axonogenesis	GO:0007409	290	0.426	Worm
oocyte differentiation	GO:0009994	145	0.416
chromatin mediated maintenance of transcription	GO:0048096	7	0.387
vesicle mediated transport	GO:0016192	381	0.374	Worm
imaginal disc derived appendage development	GO:0048737	399	0.331
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.319
chemotaxis	GO:0006935	249	0.314	Worm
axon development	GO:0061564	297	0.302	Worm
regulation of meiosis	GO:0040020	3	0.278	Worm
mitotic cell cycle phase transition	GO:0044772	138	0.277
negative regulation of neuroblast proliferation	GO:0007406	27	0.272
positive regulation of signaling	GO:0023056	243	0.265
sister chromatid segregation	GO:0000819	92	0.260
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.256
post embryonic appendage morphogenesis	GO:0035120	385	0.255
mrna metabolic process	GO:0016071	124	0.231
alternative mrna splicing via spliceosome	GO:0000380	60	0.225
regulation of cell cycle process	GO:0010564	181	0.220	Worm
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.215
wing disc morphogenesis	GO:0007472	344	0.212
macromolecular complex disassembly	GO:0032984	37	0.210
regulation of developmental growth	GO:0048638	174	0.202
muscle structure development	GO:0061061	224	0.202
regulation of cellular protein metabolic process	GO:0032268	243	0.199
cellular protein modification process	GO:0006464	438	0.199
regulation of cell division	GO:0051302	72	0.191	Worm
female meiotic division	GO:0007143	70	0.182
meiotic cytokinesis	GO:0033206	33	0.179
positive regulation of cell communication	GO:0010647	250	0.177
sex differentiation	GO:0007548	81	0.174	Worm
neurological system process	GO:0050877	358	0.173
germ line stem cell division	GO:0042078	25	0.171
negative regulation of developmental process	GO:0051093	201	0.168
protein phosphorylation	GO:0006468	169	0.164
stem cell development	GO:0048864	79	0.157
positive regulation of signal transduction	GO:0009967	223	0.153
regulation of mrna processing	GO:0050684	71	0.150
positive regulation of response to stimulus	GO:0048584	323	0.150
oocyte development	GO:0048599	124	0.146
mitotic sister chromatid segregation	GO:0000070	87	0.144
negative regulation of neurogenesis	GO:0050768	53	0.140
negative regulation of cell differentiation	GO:0045596	143	0.135
chromosome segregation	GO:0007059	157	0.134
genitalia development	GO:0048806	26	0.132	Worm
stem cell differentiation	GO:0048863	117	0.130
striated muscle cell development	GO:0055002	50	0.129
positive regulation of phosphorus metabolic process	GO:0010562	139	0.129
cytoskeleton dependent cytokinesis	GO:0061640	81	0.124
mitotic nuclear division	GO:0007067	213	0.122
negative regulation of cell development	GO:0010721	62	0.121
regulation of neurogenesis	GO:0050767	158	0.118
protein complex biogenesis	GO:0070271	201	0.117
stem cell maintenance	GO:0019827	67	0.117
appendage morphogenesis	GO:0035107	397	0.116
locomotory behavior	GO:0007626	176	0.115
body morphogenesis	GO:0010171	2	0.115
cellular protein localization	GO:0034613	160	0.114
oocyte microtubule cytoskeleton organization	GO:0016325	35	0.113
protein modification process	GO:0036211	438	0.112
g2 m transition of mitotic cell cycle	GO:0000086	19	0.111
cell cycle phase transition	GO:0044770	140	0.107
multi organism behavior	GO:0051705	175	0.104	Worm
posttranscriptional regulation of gene expression	GO:0010608	145	0.103
negative regulation of multicellular organismal process	GO:0051241	142	0.102
regulation of mapk cascade	GO:0043408	92	0.102
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.099
establishment of organelle localization	GO:0051656	122	0.097
cell maturation	GO:0048469	144	0.097
positive regulation of cellular protein metabolic process	GO:0032270	118	0.096
regulation of protein stability	GO:0031647	43	0.094
ras protein signal transduction	GO:0007265	88	0.094
positive regulation of growth	GO:0045927	75	0.092
regulation of transport	GO:0051049	181	0.088
mitotic spindle organization	GO:0007052	220	0.087
embryo development ending in birth or egg hatching	GO:0009792	152	0.087	Worm
dorsal ventral axis specification ovarian follicular epithelium	GO:0008069	13	0.084
actin filament based process	GO:0030029	220	0.084
developmental growth	GO:0048589	280	0.084
brain development	GO:0007420	120	0.083
protein localization to organelle	GO:0033365	82	0.078
positive regulation of developmental process	GO:0051094	143	0.078
organelle assembly	GO:0070925	198	0.077
cellular macromolecule localization	GO:0070727	220	0.075
single organism biosynthetic process	GO:0044711	206	0.075
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.074
regulation of neuron differentiation	GO:0045664	103	0.073
purine containing compound metabolic process	GO:0072521	155	0.073
positive regulation of intracellular signal transduction	GO:1902533	116	0.070
mating	GO:0007618	120	0.069
centrosome organization	GO:0051297	163	0.068
catabolic process	GO:0009056	409	0.068
nucleus localization	GO:0051647	34	0.067
purine ribonucleoside monophosphate catabolic process	GO:0009169	38	0.067
regulation of cellular component biogenesis	GO:0044087	201	0.066
head development	GO:0060322	135	0.066
positive regulation of cell death	GO:0010942	69	0.066
establishment of mitotic spindle orientation	GO:0000132	13	0.065
regionalization	GO:0003002	416	0.065
cellular catabolic process	GO:0044248	372	0.064
circadian rhythm	GO:0007623	105	0.064
myofibril assembly	GO:0030239	36	0.063
negative regulation of biosynthetic process	GO:0009890	277	0.062
negative regulation of cellular metabolic process	GO:0031324	382	0.061
regulation of erbb signaling pathway	GO:1901184	42	0.060
organic substance catabolic process	GO:1901575	308	0.060
germarium derived oocyte differentiation	GO:0030706	29	0.060
spindle organization	GO:0007051	253	0.059
protein modification by small protein conjugation or removal	GO:0070647	106	0.059
multicellular organismal homeostasis	GO:0048871	41	0.059
dna methylation	GO:0006306	4	0.058
neuron projection guidance	GO:0097485	241	0.057	Worm
negative regulation of meiotic cell cycle	GO:0051447	2	0.056
negative regulation of cellular component organization	GO:0051129	108	0.054
microtubule based movement	GO:0007018	51	0.054
regulation of translation	GO:0006417	56	0.054
programmed cell death	GO:0012501	257	0.054
gonad development	GO:0008406	50	0.054	Worm
regulation of localization	GO:0032879	275	0.053
photoreceptor cell differentiation	GO:0046530	170	0.051
ovarian follicle cell development	GO:0030707	248	0.051
cell motility	GO:0048870	251	0.051
meiosis i	GO:0007127	59	0.050
anatomical structure homeostasis	GO:0060249	97	0.049
positive regulation of phosphate metabolic process	GO:0045937	139	0.046
regulation of mitosis	GO:0007088	56	0.046
cystoblast division	GO:0007282	10	0.045
small gtpase mediated signal transduction	GO:0007264	88	0.045
regulation of cell cycle phase transition	GO:1901987	130	0.044
negative regulation of transcription dna templated	GO:0045892	237	0.044
pronuclear migration	GO:0035046	4	0.044
positive regulation of cellular catabolic process	GO:0031331	95	0.044
regulation of phosphorylation	GO:0042325	147	0.044
forebrain development	GO:0030900	2	0.044
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.043
lipid metabolic process	GO:0006629	121	0.043
regulation of catalytic activity	GO:0050790	185	0.042
compound eye photoreceptor fate commitment	GO:0001752	36	0.042
single organism catabolic process	GO:0044712	228	0.041
eye photoreceptor cell differentiation	GO:0001754	145	0.041
establishment of protein localization	GO:0045184	163	0.041
nuclear migration	GO:0007097	20	0.041
establishment or maintenance of microtubule cytoskeleton polarity	GO:0030951	41	0.041
dna damage checkpoint	GO:0000077	78	0.040
negative regulation of cellular protein metabolic process	GO:0032269	85	0.040
positive regulation of fibroblast growth factor receptor signaling pathway	GO:0045743	5	0.039
regulation of proteasomal protein catabolic process	GO:0061136	39	0.038
regulation of cell death	GO:0010941	173	0.038
positive regulation of nucleotide metabolic process	GO:0045981	55	0.038
regulation of membrane potential	GO:0042391	35	0.038
establishment or maintenance of cell polarity	GO:0007163	167	0.037
cellular response to sterol depletion	GO:0071501	3	0.037
establishment of localization in cell	GO:0051649	402	0.037
dna biosynthetic process	GO:0071897	24	0.037
maintenance of location in cell	GO:0051651	28	0.037
intracellular signal transduction	GO:0035556	300	0.036
positive regulation of phosphorylation	GO:0042327	87	0.036
development of primary sexual characteristics	GO:0045137	50	0.036	Worm
multicellular organismal aging	GO:0010259	140	0.036
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.035
mitotic cytokinesis	GO:0000281	50	0.035
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.034
single organism membrane organization	GO:0044802	93	0.034
dorsal ventral pattern formation	GO:0009953	133	0.034
salivary gland cell autophagic cell death	GO:0035071	83	0.034
axon guidance	GO:0007411	233	0.034	Worm
aromatic compound catabolic process	GO:0019439	166	0.034
heterocycle catabolic process	GO:0046700	166	0.034
negative regulation of cell proliferation	GO:0008285	69	0.034
positive regulation of multicellular organismal process	GO:0051240	143	0.034
dendrite morphogenesis	GO:0048813	199	0.033
larval development	GO:0002164	104	0.033	Worm
regulation of intracellular signal transduction	GO:1902531	236	0.033
actin cytoskeleton organization	GO:0030036	206	0.033
establishment of rna localization	GO:0051236	47	0.033
proteolysis	GO:0006508	192	0.033
positive regulation of erk1 and erk2 cascade	GO:0070374	36	0.033
negative regulation of growth	GO:0045926	84	0.032
mitotic dna damage checkpoint	GO:0044773	74	0.032
negative regulation of epidermal growth factor receptor signaling pathway	GO:0042059	29	0.032
regulation of cellular protein catabolic process	GO:1903362	44	0.032
eye photoreceptor cell fate commitment	GO:0042706	37	0.032
stem cell division	GO:0017145	69	0.032
endocytosis	GO:0006897	310	0.031	Worm
synapse organization	GO:0050808	196	0.031
germarium derived oocyte fate determination	GO:0007294	26	0.031
reproductive behavior	GO:0019098	122	0.031	Worm
autophagic cell death	GO:0048102	83	0.031
regulation of cellular catabolic process	GO:0031329	157	0.031
regulation of kinase activity	GO:0043549	53	0.031
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.031
regulation of mitotic sister chromatid separation	GO:0010965	28	0.030
dna methylation or demethylation	GO:0044728	4	0.030
negative regulation of rna biosynthetic process	GO:1902679	240	0.030
telencephalon development	GO:0021537	2	0.030
cellular response to chemical stimulus	GO:0070887	199	0.030
morphogenesis of follicular epithelium	GO:0016333	36	0.029
regulation of cell differentiation	GO:0045595	302	0.028
adult behavior	GO:0030534	137	0.028
protein localization	GO:0008104	284	0.028
single organism cellular localization	GO:1902580	180	0.028
regulation of intracellular transport	GO:0032386	64	0.028
macromolecular complex assembly	GO:0065003	256	0.027
meiotic cell cycle process	GO:1903046	132	0.027
regulation of protein localization	GO:0032880	76	0.027
mitotic sister chromatid separation	GO:0051306	30	0.027
protein modification by small protein removal	GO:0070646	28	0.027
negative regulation of transferase activity	GO:0051348	18	0.027
dna metabolic process	GO:0006259	227	0.026
regulation of protein metabolic process	GO:0051246	256	0.026
regulation of cellular localization	GO:0060341	136	0.026
establishment or maintenance of bipolar cell polarity	GO:0061245	34	0.026
oxoacid metabolic process	GO:0043436	103	0.025
negative regulation of organelle organization	GO:0010639	56	0.025
regulation of epidermal growth factor receptor signaling pathway	GO:0042058	42	0.025
regulation of mitotic cell cycle	GO:0007346	190	0.025
asymmetric cell division	GO:0008356	37	0.025
single organism behavior	GO:0044708	391	0.024
nucleobase containing compound catabolic process	GO:0034655	165	0.024
histolysis	GO:0007559	102	0.024
locomotor rhythm	GO:0045475	56	0.024
proteolysis involved in cellular protein catabolic process	GO:0051603	83	0.024
reproductive system development	GO:0061458	74	0.024	Worm
regulation of hemocyte proliferation	GO:0035206	37	0.024
positive regulation of apoptotic signaling pathway	GO:2001235	4	0.024
meiotic spindle organization	GO:0000212	36	0.023
glial cell fate determination	GO:0007403	3	0.023
regulation of sister chromatid cohesion	GO:0007063	2	0.023
organophosphate catabolic process	GO:0046434	112	0.023
cellular amino acid metabolic process	GO:0006520	61	0.023
regulation of ras protein signal transduction	GO:0046578	93	0.023
compound eye morphogenesis	GO:0001745	249	0.023
regulation of nervous system development	GO:0051960	248	0.023
regulation of necrotic cell death	GO:0010939	1	0.023
spindle assembly involved in mitosis	GO:0090307	50	0.023
regulation of nucleobase containing compound transport	GO:0032239	4	0.023
phagocytosis	GO:0006909	215	0.022
chorion containing eggshell formation	GO:0007304	105	0.022
spindle assembly	GO:0051225	80	0.022
striated muscle myosin thick filament assembly	GO:0071688	3	0.021
gliogenesis	GO:0042063	80	0.021
cell proliferation	GO:0008283	299	0.021	Worm
regulation of epithelial cell proliferation	GO:0050678	4	0.021
peptidyl lysine trimethylation	GO:0018023	6	0.021
lipid storage	GO:0019915	38	0.020
cell growth	GO:0016049	108	0.020
striated muscle cell differentiation	GO:0051146	90	0.020
modification dependent macromolecule catabolic process	GO:0043632	79	0.020
nucleotide catabolic process	GO:0009166	109	0.020
imaginal disc derived wing morphogenesis	GO:0007476	337	0.020
negative regulation of translation	GO:0017148	28	0.019
embryonic development via the syncytial blastoderm	GO:0001700	148	0.019
oocyte axis specification	GO:0007309	108	0.019
eye photoreceptor cell development	GO:0042462	81	0.019
signal transduction by phosphorylation	GO:0023014	107	0.019
regulation of nucleocytoplasmic transport	GO:0046822	35	0.018
regulation of erk1 and erk2 cascade	GO:0070372	39	0.018
purine ribonucleoside monophosphate metabolic process	GO:0009167	50	0.018
purine nucleoside monophosphate catabolic process	GO:0009128	38	0.018
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.018
purine nucleotide metabolic process	GO:0006163	146	0.018
positive regulation of macromolecule metabolic process	GO:0010604	405	0.018
disaccharide metabolic process	GO:0005984	4	0.018
chromosome separation	GO:0051304	42	0.018
ribonucleotide metabolic process	GO:0009259	145	0.017
regulation of ubiquitin protein transferase activity	GO:0051438	4	0.017
determination of adult lifespan	GO:0008340	137	0.017
positive regulation of proteasomal protein catabolic process	GO:1901800	20	0.017
metaphase anaphase transition of mitotic cell cycle	GO:0007091	28	0.017
translation	GO:0006412	69	0.017
induction of programmed cell death	GO:0012502	12	0.017
attachment of spindle microtubules to kinetochore	GO:0008608	5	0.017
salivary gland histolysis	GO:0035070	88	0.016
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.016
positive regulation of programmed cell death	GO:0043068	62	0.016
lateral inhibition	GO:0046331	206	0.016
compound eye photoreceptor cell differentiation	GO:0001751	140	0.016
establishment of spindle localization	GO:0051293	22	0.016
protein complex assembly	GO:0006461	200	0.016
regulation of phosphate metabolic process	GO:0019220	210	0.016
eggshell chorion gene amplification	GO:0007307	9	0.016
male gamete generation	GO:0048232	201	0.016
carbohydrate derivative catabolic process	GO:1901136	118	0.016
regulation of neuron projection development	GO:0010975	69	0.016
rna localization	GO:0006403	115	0.015
neuroblast proliferation	GO:0007405	74	0.015
chromosome organization	GO:0051276	360	0.015
regulation of proteolysis involved in cellular protein catabolic process	GO:1903050	44	0.015
membrane organization	GO:0061024	112	0.015
regulation of molecular function	GO:0065009	217	0.015
regulation of cell shape	GO:0008360	113	0.015
negative regulation of molecular function	GO:0044092	51	0.015
positive regulation of ras protein signal transduction	GO:0046579	43	0.015
muscle cell development	GO:0055001	50	0.015
purine ribonucleoside metabolic process	GO:0046128	127	0.015
regulation of cellular component size	GO:0032535	98	0.015
positive regulation of intracellular transport	GO:0032388	42	0.015
peptidyl threonine phosphorylation	GO:0018107	2	0.015
adherens junction organization	GO:0034332	27	0.015
induction of programmed cell death by ecdysone	GO:0035078	12	0.014
negative regulation of protein modification process	GO:0031400	29	0.014
pigmentation	GO:0043473	75	0.014
wnt signaling pathway	GO:0016055	98	0.014
ribonucleoprotein complex biogenesis	GO:0022613	31	0.014
dna alkylation	GO:0006305	4	0.014
imaginal disc derived wing margin morphogenesis	GO:0008587	41	0.014
regulation of chromosome organization	GO:0033044	64	0.014
photoreceptor cell development	GO:0042461	96	0.014
regulation of meiotic cell cycle	GO:0051445	9	0.014	Worm
negative regulation of protein metabolic process	GO:0051248	85	0.014
neuron fate commitment	GO:0048663	50	0.014
oocyte dorsal ventral axis specification	GO:0007310	34	0.014
cellular component assembly involved in morphogenesis	GO:0010927	151	0.014
regulation of transferase activity	GO:0051338	58	0.014
regulation of mitotic sister chromatid segregation	GO:0033047	28	0.014
centrosome cycle	GO:0007098	137	0.014
nuclear transport	GO:0051169	72	0.014
modification dependent protein catabolic process	GO:0019941	78	0.014
mating behavior	GO:0007617	106	0.014
regulation of cell junction assembly	GO:1901888	2	0.014
positive regulation of gene expression	GO:0010628	290	0.014
dendrite development	GO:0016358	204	0.014
purine ribonucleotide metabolic process	GO:0009150	145	0.014
leg disc morphogenesis	GO:0007478	80	0.013
negative regulation of response to stimulus	GO:0048585	258	0.013
positive regulation of catabolic process	GO:0009896	105	0.013
actomyosin contractile ring assembly	GO:0000915	10	0.013
regulation of cellular ketone metabolic process	GO:0010565	3	0.013
regulation of phosphatase activity	GO:0010921	3	0.013
establishment of protein localization to organelle	GO:0072594	62	0.013
cytoplasmic transport	GO:0016482	130	0.013
organonitrogen compound metabolic process	GO:1901564	318	0.013
atp catabolic process	GO:0006200	38	0.012
inter male aggressive behavior	GO:0002121	60	0.012
nucleoside phosphate metabolic process	GO:0006753	162	0.012
organic cyclic compound catabolic process	GO:1901361	168	0.012
positive regulation of mapk cascade	GO:0043410	63	0.012
regulation of cellular response to stress	GO:0080135	89	0.012
cellular macromolecule catabolic process	GO:0044265	136	0.012
positive regulation of purine nucleotide catabolic process	GO:0033123	46	0.012
negative regulation of phosphorus metabolic process	GO:0010563	45	0.012
maintenance of location	GO:0051235	73	0.012
regulation of insulin like growth factor receptor signaling pathway	GO:0043567	3	0.012
cell cell junction assembly	GO:0007043	38	0.012
negative regulation of signal transduction by p53 class mediator	GO:1901797	1	0.012
cellular response to insulin stimulus	GO:0032869	28	0.012
imaginal disc derived leg morphogenesis	GO:0007480	80	0.012
activation of jun kinase activity	GO:0007257	3	0.012
cell death	GO:0008219	279	0.012
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.012
germline stem cell asymmetric division	GO:0098728	15	0.012
mitotic spindle stabilization	GO:0043148	6	0.012
spermatid development	GO:0007286	98	0.012
rhythmic process	GO:0048511	106	0.012
cell recognition	GO:0008037	102	0.012	Worm
eye morphogenesis	GO:0048592	260	0.012
wing disc pattern formation	GO:0035222	66	0.011
developmental programmed cell death	GO:0010623	138	0.011
ecdysone mediated induction of salivary gland cell autophagic cell death	GO:0035072	12	0.011
male meiosis cytokinesis	GO:0007112	26	0.011
negative regulation of proteasomal ubiquitin dependent protein catabolic process	GO:0032435	16	0.011
regulation of programmed cell death	GO:0043067	152	0.011
erk1 and erk2 cascade	GO:0070371	39	0.011
regulation of protein kinase activity	GO:0045859	51	0.011
positive regulation of small gtpase mediated signal transduction	GO:0051057	43	0.011
protein modification by small protein conjugation	GO:0032446	79	0.011
positive regulation of developmental growth	GO:0048639	62	0.011
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.011
negative regulation of cyclin dependent protein serine threonine kinase activity	GO:0045736	1	0.011
glial cell differentiation	GO:0010001	35	0.011
receptor mediated endocytosis	GO:0006898	21	0.011	Worm
oocyte maturation	GO:0001556	3	0.011
regulation of neuroblast proliferation	GO:1902692	34	0.011
microtubule organizing center organization	GO:0031023	168	0.011
regulation of chromosome segregation	GO:0051983	32	0.011
establishment of spindle orientation	GO:0051294	18	0.011
female germ line cyst formation	GO:0048135	42	0.011
tissue death	GO:0016271	102	0.011
negative regulation of neural precursor cell proliferation	GO:2000178	27	0.011
g2 dna damage checkpoint	GO:0031572	69	0.011
central nervous system development	GO:0007417	201	0.011
nucleoside phosphate catabolic process	GO:1901292	110	0.011
ribonucleoside monophosphate metabolic process	GO:0009161	51	0.011
negative regulation of gene expression	GO:0010629	387	0.011
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.011
regulation of nucleotide catabolic process	GO:0030811	48	0.010
regulation of sister chromatid segregation	GO:0033045	28	0.010
regulation of phosphorus metabolic process	GO:0051174	210	0.010
positive regulation of translation	GO:0045727	12	0.010
positive regulation of transport	GO:0051050	92	0.010
macromolecule catabolic process	GO:0009057	161	0.010
regulation of cell cycle	GO:0051726	291	0.010
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.010
ribose phosphate metabolic process	GO:0019693	145	0.010
regulation of anatomical structure morphogenesis	GO:0022603	242	0.010

pUf68 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.015
	nervous system disease	DOID:863	0	0.015

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