Drosophila melanogaster

89 known processes

pUf68 (Dmel_CG12085)

poly U binding factor 68kD

(Aliases: Fir,hfp,Dmel\CG12085,anon-WO0118547.408,HFP,CG12085,Puf60,PUF60,dFIR,DPUF68,Hfp,pUbsf)

pUf68 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
rna splicingGO:0008380830.999
cell divisionGO:00513012480.992
meiotic nuclear divisionGO:00071261510.982
Worm
organelle fissionGO:00482853400.981
Worm
regulation of rna splicingGO:0043484690.981
nuclear divisionGO:00002803320.954
Worm
mrna splicing via spliceosomeGO:0000398730.937
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377730.920
regulation of mrna splicing via spliceosomeGO:0048024640.912
germarium derived egg chamber formationGO:00072931010.863
regulation of alternative mrna splicing via spliceosomeGO:0000381600.830
meiotic cell cycleGO:00513211710.797
Worm
rna splicing via transesterification reactionsGO:0000375730.781
growthGO:00400073590.736
reproductive structure developmentGO:0048608740.701
Worm
male meiosisGO:0007140520.662
taxisGO:00423303040.662
Worm
organelle localizationGO:00516401480.658
regulation of nuclear divisionGO:0051783580.615
Worm
cytokinesisGO:0000910900.597
negative regulation of cellular biosynthetic processGO:00313272770.583
regulation of growthGO:00400082330.569
phosphorylationGO:00163102940.548
appendage developmentGO:00487364010.506
rna processingGO:00063961470.453
mrna processingGO:00063971040.450
regulation of mrna metabolic processGO:1903311720.437
axonogenesisGO:00074092900.426
Worm
oocyte differentiationGO:00099941450.416
chromatin mediated maintenance of transcriptionGO:004809670.387
vesicle mediated transportGO:00161923810.374
Worm
imaginal disc derived appendage developmentGO:00487373990.331
negative regulation of nucleobase containing compound metabolic processGO:00459342610.319
chemotaxisGO:00069352490.314
Worm
axon developmentGO:00615642970.302
Worm
regulation of meiosisGO:004002030.278
Worm
mitotic cell cycle phase transitionGO:00447721380.277
negative regulation of neuroblast proliferationGO:0007406270.272
positive regulation of signalingGO:00230562430.265
sister chromatid segregationGO:0000819920.260
imaginal disc derived appendage morphogenesisGO:00351143950.256
post embryonic appendage morphogenesisGO:00351203850.255
mrna metabolic processGO:00160711240.231
alternative mrna splicing via spliceosomeGO:0000380600.225
regulation of cell cycle processGO:00105641810.220
Worm
negative regulation of nitrogen compound metabolic processGO:00511722650.215
wing disc morphogenesisGO:00074723440.212
macromolecular complex disassemblyGO:0032984370.210
regulation of developmental growthGO:00486381740.202
muscle structure developmentGO:00610612240.202
regulation of cellular protein metabolic processGO:00322682430.199
cellular protein modification processGO:00064644380.199
regulation of cell divisionGO:0051302720.191
Worm
female meiotic divisionGO:0007143700.182
meiotic cytokinesisGO:0033206330.179
positive regulation of cell communicationGO:00106472500.177
sex differentiationGO:0007548810.174
Worm
neurological system processGO:00508773580.173
germ line stem cell divisionGO:0042078250.171
negative regulation of developmental processGO:00510932010.168
protein phosphorylationGO:00064681690.164
stem cell developmentGO:0048864790.157
positive regulation of signal transductionGO:00099672230.153
regulation of mrna processingGO:0050684710.150
positive regulation of response to stimulusGO:00485843230.150
oocyte developmentGO:00485991240.146
mitotic sister chromatid segregationGO:0000070870.144
negative regulation of neurogenesisGO:0050768530.140
negative regulation of cell differentiationGO:00455961430.135
chromosome segregationGO:00070591570.134
genitalia developmentGO:0048806260.132
Worm
stem cell differentiationGO:00488631170.130
striated muscle cell developmentGO:0055002500.129
positive regulation of phosphorus metabolic processGO:00105621390.129
cytoskeleton dependent cytokinesisGO:0061640810.124
mitotic nuclear divisionGO:00070672130.122
negative regulation of cell developmentGO:0010721620.121
regulation of neurogenesisGO:00507671580.118
protein complex biogenesisGO:00702712010.117
stem cell maintenanceGO:0019827670.117
appendage morphogenesisGO:00351073970.116
locomotory behaviorGO:00076261760.115
body morphogenesisGO:001017120.115
cellular protein localizationGO:00346131600.114
oocyte microtubule cytoskeleton organizationGO:0016325350.113
protein modification processGO:00362114380.112
g2 m transition of mitotic cell cycleGO:0000086190.111
cell cycle phase transitionGO:00447701400.107
multi organism behaviorGO:00517051750.104
Worm
posttranscriptional regulation of gene expressionGO:00106081450.103
negative regulation of multicellular organismal processGO:00512411420.102
regulation of mapk cascadeGO:0043408920.102
negative regulation of nucleic acid templated transcriptionGO:19035072400.099
establishment of organelle localizationGO:00516561220.097
cell maturationGO:00484691440.097
positive regulation of cellular protein metabolic processGO:00322701180.096
regulation of protein stabilityGO:0031647430.094
ras protein signal transductionGO:0007265880.094
positive regulation of growthGO:0045927750.092
regulation of transportGO:00510491810.088
mitotic spindle organizationGO:00070522200.087
embryo development ending in birth or egg hatchingGO:00097921520.087
Worm
dorsal ventral axis specification ovarian follicular epitheliumGO:0008069130.084
actin filament based processGO:00300292200.084
developmental growthGO:00485892800.084
brain developmentGO:00074201200.083
protein localization to organelleGO:0033365820.078
positive regulation of developmental processGO:00510941430.078
organelle assemblyGO:00709251980.077
cellular macromolecule localizationGO:00707272200.075
single organism biosynthetic processGO:00447112060.075
positive regulation of nitrogen compound metabolic processGO:00511733540.074
regulation of neuron differentiationGO:00456641030.073
purine containing compound metabolic processGO:00725211550.073
positive regulation of intracellular signal transductionGO:19025331160.070
matingGO:00076181200.069
centrosome organizationGO:00512971630.068
catabolic processGO:00090564090.068
nucleus localizationGO:0051647340.067
purine ribonucleoside monophosphate catabolic processGO:0009169380.067
regulation of cellular component biogenesisGO:00440872010.066
head developmentGO:00603221350.066
positive regulation of cell deathGO:0010942690.066
establishment of mitotic spindle orientationGO:0000132130.065
regionalizationGO:00030024160.065
cellular catabolic processGO:00442483720.064
circadian rhythmGO:00076231050.064
myofibril assemblyGO:0030239360.063
negative regulation of biosynthetic processGO:00098902770.062
negative regulation of cellular metabolic processGO:00313243820.061
regulation of erbb signaling pathwayGO:1901184420.060
organic substance catabolic processGO:19015753080.060
germarium derived oocyte differentiationGO:0030706290.060
spindle organizationGO:00070512530.059
protein modification by small protein conjugation or removalGO:00706471060.059
multicellular organismal homeostasisGO:0048871410.059
dna methylationGO:000630640.058
neuron projection guidanceGO:00974852410.057
Worm
negative regulation of meiotic cell cycleGO:005144720.056
negative regulation of cellular component organizationGO:00511291080.054
microtubule based movementGO:0007018510.054
regulation of translationGO:0006417560.054
programmed cell deathGO:00125012570.054
gonad developmentGO:0008406500.054
Worm
regulation of localizationGO:00328792750.053
photoreceptor cell differentiationGO:00465301700.051
ovarian follicle cell developmentGO:00307072480.051
cell motilityGO:00488702510.051
meiosis iGO:0007127590.050
anatomical structure homeostasisGO:0060249970.049
positive regulation of phosphate metabolic processGO:00459371390.046
regulation of mitosisGO:0007088560.046
cystoblast divisionGO:0007282100.045
small gtpase mediated signal transductionGO:0007264880.045
regulation of cell cycle phase transitionGO:19019871300.044
negative regulation of transcription dna templatedGO:00458922370.044
pronuclear migrationGO:003504640.044
positive regulation of cellular catabolic processGO:0031331950.044
regulation of phosphorylationGO:00423251470.044
forebrain developmentGO:003090020.044
purine nucleoside triphosphate catabolic processGO:00091461080.043
lipid metabolic processGO:00066291210.043
regulation of catalytic activityGO:00507901850.042
compound eye photoreceptor fate commitmentGO:0001752360.042
single organism catabolic processGO:00447122280.041
eye photoreceptor cell differentiationGO:00017541450.041
establishment of protein localizationGO:00451841630.041
nuclear migrationGO:0007097200.041
establishment or maintenance of microtubule cytoskeleton polarityGO:0030951410.041
dna damage checkpointGO:0000077780.040
negative regulation of cellular protein metabolic processGO:0032269850.040
positive regulation of fibroblast growth factor receptor signaling pathwayGO:004574350.039
regulation of proteasomal protein catabolic processGO:0061136390.038
regulation of cell deathGO:00109411730.038
positive regulation of nucleotide metabolic processGO:0045981550.038
regulation of membrane potentialGO:0042391350.038
establishment or maintenance of cell polarityGO:00071631670.037
cellular response to sterol depletionGO:007150130.037
establishment of localization in cellGO:00516494020.037
dna biosynthetic processGO:0071897240.037
maintenance of location in cellGO:0051651280.037
intracellular signal transductionGO:00355563000.036
positive regulation of phosphorylationGO:0042327870.036
development of primary sexual characteristicsGO:0045137500.036
Worm
multicellular organismal agingGO:00102591400.036
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.035
mitotic cytokinesisGO:0000281500.035
ribonucleoside triphosphate catabolic processGO:00092031080.034
single organism membrane organizationGO:0044802930.034
dorsal ventral pattern formationGO:00099531330.034
salivary gland cell autophagic cell deathGO:0035071830.034
axon guidanceGO:00074112330.034
Worm
aromatic compound catabolic processGO:00194391660.034
heterocycle catabolic processGO:00467001660.034
negative regulation of cell proliferationGO:0008285690.034
positive regulation of multicellular organismal processGO:00512401430.034
dendrite morphogenesisGO:00488131990.033
larval developmentGO:00021641040.033
Worm
regulation of intracellular signal transductionGO:19025312360.033
actin cytoskeleton organizationGO:00300362060.033
establishment of rna localizationGO:0051236470.033
proteolysisGO:00065081920.033
positive regulation of erk1 and erk2 cascadeGO:0070374360.033
negative regulation of growthGO:0045926840.032
mitotic dna damage checkpointGO:0044773740.032
negative regulation of epidermal growth factor receptor signaling pathwayGO:0042059290.032
regulation of cellular protein catabolic processGO:1903362440.032
eye photoreceptor cell fate commitmentGO:0042706370.032
stem cell divisionGO:0017145690.032
endocytosisGO:00068973100.031
Worm
synapse organizationGO:00508081960.031
germarium derived oocyte fate determinationGO:0007294260.031
reproductive behaviorGO:00190981220.031
Worm
autophagic cell deathGO:0048102830.031
regulation of cellular catabolic processGO:00313291570.031
regulation of kinase activityGO:0043549530.031
regulation of transcription from rna polymerase ii promoterGO:00063573780.031
regulation of mitotic sister chromatid separationGO:0010965280.030
dna methylation or demethylationGO:004472840.030
negative regulation of rna biosynthetic processGO:19026792400.030
telencephalon developmentGO:002153720.030
cellular response to chemical stimulusGO:00708871990.030
morphogenesis of follicular epitheliumGO:0016333360.029
regulation of cell differentiationGO:00455953020.028
adult behaviorGO:00305341370.028
protein localizationGO:00081042840.028
single organism cellular localizationGO:19025801800.028
regulation of intracellular transportGO:0032386640.028
macromolecular complex assemblyGO:00650032560.027
meiotic cell cycle processGO:19030461320.027
regulation of protein localizationGO:0032880760.027
mitotic sister chromatid separationGO:0051306300.027
protein modification by small protein removalGO:0070646280.027
negative regulation of transferase activityGO:0051348180.027
dna metabolic processGO:00062592270.026
regulation of protein metabolic processGO:00512462560.026
regulation of cellular localizationGO:00603411360.026
establishment or maintenance of bipolar cell polarityGO:0061245340.026
oxoacid metabolic processGO:00434361030.025
negative regulation of organelle organizationGO:0010639560.025
regulation of epidermal growth factor receptor signaling pathwayGO:0042058420.025
regulation of mitotic cell cycleGO:00073461900.025
asymmetric cell divisionGO:0008356370.025
single organism behaviorGO:00447083910.024
nucleobase containing compound catabolic processGO:00346551650.024
histolysisGO:00075591020.024
locomotor rhythmGO:0045475560.024
proteolysis involved in cellular protein catabolic processGO:0051603830.024
reproductive system developmentGO:0061458740.024
Worm
regulation of hemocyte proliferationGO:0035206370.024
positive regulation of apoptotic signaling pathwayGO:200123540.024
meiotic spindle organizationGO:0000212360.023
glial cell fate determinationGO:000740330.023
regulation of sister chromatid cohesionGO:000706320.023
organophosphate catabolic processGO:00464341120.023
cellular amino acid metabolic processGO:0006520610.023
regulation of ras protein signal transductionGO:0046578930.023
compound eye morphogenesisGO:00017452490.023
regulation of nervous system developmentGO:00519602480.023
regulation of necrotic cell deathGO:001093910.023
spindle assembly involved in mitosisGO:0090307500.023
regulation of nucleobase containing compound transportGO:003223940.023
phagocytosisGO:00069092150.022
chorion containing eggshell formationGO:00073041050.022
spindle assemblyGO:0051225800.022
striated muscle myosin thick filament assemblyGO:007168830.021
gliogenesisGO:0042063800.021
cell proliferationGO:00082832990.021
Worm
regulation of epithelial cell proliferationGO:005067840.021
peptidyl lysine trimethylationGO:001802360.021
lipid storageGO:0019915380.020
cell growthGO:00160491080.020
striated muscle cell differentiationGO:0051146900.020
modification dependent macromolecule catabolic processGO:0043632790.020
nucleotide catabolic processGO:00091661090.020
imaginal disc derived wing morphogenesisGO:00074763370.020
negative regulation of translationGO:0017148280.019
embryonic development via the syncytial blastodermGO:00017001480.019
oocyte axis specificationGO:00073091080.019
eye photoreceptor cell developmentGO:0042462810.019
signal transduction by phosphorylationGO:00230141070.019
regulation of nucleocytoplasmic transportGO:0046822350.018
regulation of erk1 and erk2 cascadeGO:0070372390.018
purine ribonucleoside monophosphate metabolic processGO:0009167500.018
purine nucleoside monophosphate catabolic processGO:0009128380.018
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.018
purine nucleotide metabolic processGO:00061631460.018
positive regulation of macromolecule metabolic processGO:00106044050.018
disaccharide metabolic processGO:000598440.018
chromosome separationGO:0051304420.018
ribonucleotide metabolic processGO:00092591450.017
regulation of ubiquitin protein transferase activityGO:005143840.017
determination of adult lifespanGO:00083401370.017
positive regulation of proteasomal protein catabolic processGO:1901800200.017
metaphase anaphase transition of mitotic cell cycleGO:0007091280.017
translationGO:0006412690.017
induction of programmed cell deathGO:0012502120.017
attachment of spindle microtubules to kinetochoreGO:000860850.017
salivary gland histolysisGO:0035070880.016
regulation of small gtpase mediated signal transductionGO:0051056930.016
positive regulation of programmed cell deathGO:0043068620.016
lateral inhibitionGO:00463312060.016
compound eye photoreceptor cell differentiationGO:00017511400.016
establishment of spindle localizationGO:0051293220.016
protein complex assemblyGO:00064612000.016
regulation of phosphate metabolic processGO:00192202100.016
eggshell chorion gene amplificationGO:000730790.016
male gamete generationGO:00482322010.016
carbohydrate derivative catabolic processGO:19011361180.016
regulation of neuron projection developmentGO:0010975690.016
rna localizationGO:00064031150.015
neuroblast proliferationGO:0007405740.015
chromosome organizationGO:00512763600.015
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.015
membrane organizationGO:00610241120.015
regulation of molecular functionGO:00650092170.015
regulation of cell shapeGO:00083601130.015
negative regulation of molecular functionGO:0044092510.015
positive regulation of ras protein signal transductionGO:0046579430.015
muscle cell developmentGO:0055001500.015
purine ribonucleoside metabolic processGO:00461281270.015
regulation of cellular component sizeGO:0032535980.015
positive regulation of intracellular transportGO:0032388420.015
peptidyl threonine phosphorylationGO:001810720.015
adherens junction organizationGO:0034332270.015
induction of programmed cell death by ecdysoneGO:0035078120.014
negative regulation of protein modification processGO:0031400290.014
pigmentationGO:0043473750.014
wnt signaling pathwayGO:0016055980.014
ribonucleoprotein complex biogenesisGO:0022613310.014
dna alkylationGO:000630540.014
imaginal disc derived wing margin morphogenesisGO:0008587410.014
regulation of chromosome organizationGO:0033044640.014
photoreceptor cell developmentGO:0042461960.014
regulation of meiotic cell cycleGO:005144590.014
Worm
negative regulation of protein metabolic processGO:0051248850.014
neuron fate commitmentGO:0048663500.014
oocyte dorsal ventral axis specificationGO:0007310340.014
cellular component assembly involved in morphogenesisGO:00109271510.014
regulation of transferase activityGO:0051338580.014
regulation of mitotic sister chromatid segregationGO:0033047280.014
centrosome cycleGO:00070981370.014
nuclear transportGO:0051169720.014
modification dependent protein catabolic processGO:0019941780.014
mating behaviorGO:00076171060.014
regulation of cell junction assemblyGO:190188820.014
positive regulation of gene expressionGO:00106282900.014
dendrite developmentGO:00163582040.014
purine ribonucleotide metabolic processGO:00091501450.014
leg disc morphogenesisGO:0007478800.013
negative regulation of response to stimulusGO:00485852580.013
positive regulation of catabolic processGO:00098961050.013
actomyosin contractile ring assemblyGO:0000915100.013
regulation of cellular ketone metabolic processGO:001056530.013
regulation of phosphatase activityGO:001092130.013
establishment of protein localization to organelleGO:0072594620.013
cytoplasmic transportGO:00164821300.013
organonitrogen compound metabolic processGO:19015643180.013
atp catabolic processGO:0006200380.012
inter male aggressive behaviorGO:0002121600.012
nucleoside phosphate metabolic processGO:00067531620.012
organic cyclic compound catabolic processGO:19013611680.012
positive regulation of mapk cascadeGO:0043410630.012
regulation of cellular response to stressGO:0080135890.012
cellular macromolecule catabolic processGO:00442651360.012
positive regulation of purine nucleotide catabolic processGO:0033123460.012
negative regulation of phosphorus metabolic processGO:0010563450.012
maintenance of locationGO:0051235730.012
regulation of insulin like growth factor receptor signaling pathwayGO:004356730.012
cell cell junction assemblyGO:0007043380.012
negative regulation of signal transduction by p53 class mediatorGO:190179710.012
cellular response to insulin stimulusGO:0032869280.012
imaginal disc derived leg morphogenesisGO:0007480800.012
activation of jun kinase activityGO:000725730.012
cell deathGO:00082192790.012
negative regulation of macromolecule biosynthetic processGO:00105582700.012
germline stem cell asymmetric divisionGO:0098728150.012
mitotic spindle stabilizationGO:004314860.012
spermatid developmentGO:0007286980.012
rhythmic processGO:00485111060.012
cell recognitionGO:00080371020.012
Worm
eye morphogenesisGO:00485922600.012
wing disc pattern formationGO:0035222660.011
developmental programmed cell deathGO:00106231380.011
ecdysone mediated induction of salivary gland cell autophagic cell deathGO:0035072120.011
male meiosis cytokinesisGO:0007112260.011
negative regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032435160.011
regulation of programmed cell deathGO:00430671520.011
erk1 and erk2 cascadeGO:0070371390.011
regulation of protein kinase activityGO:0045859510.011
positive regulation of small gtpase mediated signal transductionGO:0051057430.011
protein modification by small protein conjugationGO:0032446790.011
positive regulation of developmental growthGO:0048639620.011
ribonucleoside triphosphate metabolic processGO:00091991190.011
negative regulation of cyclin dependent protein serine threonine kinase activityGO:004573610.011
glial cell differentiationGO:0010001350.011
receptor mediated endocytosisGO:0006898210.011
Worm
oocyte maturationGO:000155630.011
regulation of neuroblast proliferationGO:1902692340.011
microtubule organizing center organizationGO:00310231680.011
regulation of chromosome segregationGO:0051983320.011
establishment of spindle orientationGO:0051294180.011
female germ line cyst formationGO:0048135420.011
tissue deathGO:00162711020.011
negative regulation of neural precursor cell proliferationGO:2000178270.011
g2 dna damage checkpointGO:0031572690.011
central nervous system developmentGO:00074172010.011
nucleoside phosphate catabolic processGO:19012921100.011
ribonucleoside monophosphate metabolic processGO:0009161510.011
negative regulation of gene expressionGO:00106293870.011
cell cell signaling involved in cell fate commitmentGO:00451682100.011
regulation of nucleotide catabolic processGO:0030811480.010
regulation of sister chromatid segregationGO:0033045280.010
regulation of phosphorus metabolic processGO:00511742100.010
positive regulation of translationGO:0045727120.010
positive regulation of transportGO:0051050920.010
macromolecule catabolic processGO:00090571610.010
regulation of cell cycleGO:00517262910.010
purine nucleoside triphosphate metabolic processGO:00091441190.010
ribose phosphate metabolic processGO:00196931450.010
regulation of anatomical structure morphogenesisGO:00226032420.010

pUf68 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.015
nervous system diseaseDOID:86300.015