Drosophila melanogaster

137 known processes

Cdk8 (Dmel_CG10572)

Cyclin-dependent kinase 8

(Aliases: Dmel\CG10572,CG10572,DmCdk8,cdk8,p58,dTRAP56,CDK8)

Cdk8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
transcription from rna polymerase ii promoterGO:00063663680.487
Yeast
axonogenesisGO:00074092900.244
regulation of transcription from rna polymerase ii promoterGO:00063573780.209
Yeast
sex comb developmentGO:004549880.182
regulation of cell differentiationGO:00455953020.175
regulation of nervous system developmentGO:00519602480.164
multi organism reproductive behaviorGO:00447051210.155
regulation of neural precursor cell proliferationGO:2000177350.130
peptidyl lysine modificationGO:0018205570.127
positive regulation of transcription dna templatedGO:00458932660.122
Yeast
negative regulation of developmental processGO:00510932010.110
Worm
cell cycle phase transitionGO:00447701400.108
negative regulation of stem cell proliferationGO:2000647300.107
muscle structure developmentGO:00610612240.099
positive regulation of cellular biosynthetic processGO:00313283160.097
Yeast
regulation of neuroblast proliferationGO:1902692340.093
multi organism behaviorGO:00517051750.093
mitotic cell cycle phase transitionGO:00447721380.091
dendrite developmentGO:00163582040.087
positive regulation of macromolecule metabolic processGO:00106044050.085
Yeast
multicellular organismal reproductive behaviorGO:00330571100.082
post embryonic appendage morphogenesisGO:00351203850.082
negative regulation of neural precursor cell proliferationGO:2000178270.078
multi multicellular organism processGO:00447061230.076
compound eye developmentGO:00487493070.074
negative regulation of multicellular organismal processGO:00512411420.070
Worm
cellular response to dna damage stimulusGO:00069742230.070
negative regulation of nervous system developmentGO:0051961920.069
regulation of cell developmentGO:00602842150.068
protein modification processGO:00362114380.068
regulation of neurogenesisGO:00507671580.067
stem cell maintenanceGO:0019827670.067
negative regulation of neuroblast proliferationGO:0007406270.065
positive regulation of nucleic acid templated transcriptionGO:19035082660.065
Yeast
regionalizationGO:00030024160.063
neuron projection guidanceGO:00974852410.060
positive regulation of nucleobase containing compound metabolic processGO:00459353320.058
Yeast
regulation of immune system processGO:00026821760.058
peptidyl lysine acetylationGO:0018394390.057
tissue morphogenesisGO:00487292970.055
body morphogenesisGO:001017120.055
Worm
regulation of cellular component biogenesisGO:00440872010.053
regulation of cell cycleGO:00517262910.053
cell cycle checkpointGO:0000075950.052
negative regulation of mitotic cell cycle phase transitionGO:19019911030.052
salivary gland cell autophagic cell deathGO:0035071830.051
segmentationGO:00352822070.051
taxisGO:00423303040.051
mitotic g2 dna damage checkpointGO:0007095690.050
regulation of tor signalingGO:0032006210.049
negative regulation of macromolecule biosynthetic processGO:00105582700.049
Yeast
positive regulation of cell communicationGO:00106472500.048
mitotic dna integrity checkpointGO:0044774750.043
mitotic nuclear divisionGO:00070672130.043
muscle organ developmentGO:00075171270.042
negative regulation of cellular metabolic processGO:00313243820.042
Yeast
negative regulation of cell cycleGO:00457861160.041
regulation of stem cell proliferationGO:0072091400.041
leg disc morphogenesisGO:0007478800.040
negative regulation of biosynthetic processGO:00098902770.040
Yeast
chromatin organizationGO:00063252070.040
growthGO:00400073590.039
Yeast
regulation of protein modification by small protein conjugation or removalGO:1903320250.039
organ growthGO:0035265560.038
negative regulation of nucleobase containing compound metabolic processGO:00459342610.038
Yeast
negative regulation of cellular biosynthetic processGO:00313272770.037
Yeast
positive regulation of response to stimulusGO:00485843230.037
negative regulation of gene expressionGO:00106293870.036
Yeast
cellular protein modification processGO:00064644380.035
negative regulation of rna biosynthetic processGO:19026792400.035
Yeast
eye developmentGO:00016543230.035
regulation of wnt signaling pathwayGO:0030111680.035
response to oxygen containing compoundGO:19017002000.034
macromolecule catabolic processGO:00090571610.032
Yeast
dna repairGO:0006281540.032
negative regulation of transcription dna templatedGO:00458922370.032
Yeast
negative regulation of cell cycle phase transitionGO:19019881030.031
negative regulation of response to stimulusGO:00485852580.031
nuclear divisionGO:00002803320.031
regulation of immune responseGO:00507761180.031
positive regulation of gene expressionGO:00106282900.030
Yeast
imaginal disc derived appendage morphogenesisGO:00351143950.030
appendage segmentationGO:0035285260.030
regulation of protein metabolic processGO:00512462560.030
appendage developmentGO:00487364010.029
positive regulation of macromolecule biosynthetic processGO:00105572830.029
Yeast
negative regulation of cell cycle processGO:00109481090.028
appendage morphogenesisGO:00351073970.028
dna integrity checkpointGO:0031570810.028
protein acetylationGO:0006473390.028
chromatin modificationGO:00165681470.027
response to ecdysoneGO:0035075340.027
mitotic g2 m transition checkpointGO:0044818700.027
imaginal disc derived leg segmentationGO:0036011260.027
response to heatGO:0009408630.026
neuroblast proliferationGO:0007405740.026
axon guidanceGO:00074112330.026
positive regulation of nitrogen compound metabolic processGO:00511733540.026
Yeast
regulation of intracellular signal transductionGO:19025312360.026
cellular component assembly involved in morphogenesisGO:00109271510.026
negative regulation of cell developmentGO:0010721620.025
negative regulation of cell differentiationGO:00455961430.025
camera type eye developmentGO:004301040.025
response to light stimulusGO:00094161240.025
positive regulation of signalingGO:00230562430.025
negative regulation of mitotic cell cycleGO:00459301090.025
protein localizationGO:00081042840.025
regulation of synapse assemblyGO:0051963940.024
compound eye morphogenesisGO:00017452490.024
exocrine system developmentGO:00352721620.024
stem cell proliferationGO:0072089880.024
gland developmentGO:00487321910.024
regulation of response to stressGO:00801342000.024
leg disc developmentGO:0035218920.023
morphogenesis of an epitheliumGO:00020092760.022
imaginal disc pattern formationGO:0007447910.022
internal protein amino acid acetylationGO:0006475380.022
establishment or maintenance of cell polarityGO:00071631670.022
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.021
Yeast
response to abiotic stimulusGO:00096283410.021
wing disc morphogenesisGO:00074723440.021
sensory organ morphogenesisGO:00905962600.021
male gamete generationGO:00482322010.020
kidney developmentGO:000182230.020
cellular protein complex assemblyGO:0043623710.020
reproductive behaviorGO:00190981220.020
cellular ketone metabolic processGO:0042180240.020
negative regulation of nucleic acid templated transcriptionGO:19035072400.020
Yeast
regulation of multicellular organismal developmentGO:20000264140.020
Worm
protein ubiquitinationGO:0016567700.020
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.019
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.019
Yeast
snrna 3 end processingGO:0034472140.019
positive regulation of signal transductionGO:00099672230.019
developmental programmed cell deathGO:00106231380.019
imaginal disc derived wing morphogenesisGO:00074763370.019
proteolysisGO:00065081920.018
histolysisGO:00075591020.018
regulation of organ morphogenesisGO:2000027780.018
negative regulation of nitrogen compound metabolic processGO:00511722650.018
Yeast
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.018
Yeast
gland morphogenesisGO:00226121450.018
cell cell signaling involved in cell fate commitmentGO:00451682100.018
peptidyl amino acid modificationGO:00181931050.017
cellular macromolecular complex assemblyGO:00346221530.017
regulation of catalytic activityGO:00507901850.017
autophagic cell deathGO:0048102830.017
positive regulation of protein deacetylationGO:009031220.017
central nervous system developmentGO:00074172010.017
tor signalingGO:0031929320.017
negative regulation of rna metabolic processGO:00512532510.017
Yeast
protein phosphorylationGO:00064681690.017
chromosome organizationGO:00512763600.017
regulation of humoral immune responseGO:0002920510.017
negative regulation of signal transductionGO:00099682060.017
developmental growthGO:00485892800.017
protein complex biogenesisGO:00702712010.017
organelle assemblyGO:00709251980.017
regulation of antimicrobial humoral responseGO:0002759500.016
histone modificationGO:00165701060.016
salivary gland developmentGO:00074311620.016
protein alkylationGO:0008213430.016
salivary gland histolysisGO:0035070880.016
regulation of molecular functionGO:00650092170.015
photoreceptor cell differentiationGO:00465301700.015
mitotic cell cycle checkpointGO:0007093880.015
regulation of notch signaling pathwayGO:00085931000.015
striated muscle myosin thick filament assemblyGO:007168830.015
imaginal disc derived appendage developmentGO:00487373990.015
macromolecular complex assemblyGO:00650032560.015
dna endoreduplicationGO:0042023220.015
intracellular signal transductionGO:00355563000.015
embryonic axis specificationGO:00005781070.015
positive regulation of biosynthetic processGO:00098913160.015
Yeast
mitotic cell cycle embryonicGO:0045448380.015
positive regulation of protein metabolic processGO:00512471280.014
regulation of cellular protein metabolic processGO:00322682430.014
cell cycle dna replicationGO:0044786230.014
striated muscle cell differentiationGO:0051146900.014
negative regulation of cell communicationGO:00106482230.014
regulation of protein deacetylationGO:009031120.014
sex differentiationGO:0007548810.014
positive regulation of cellular component biogenesisGO:0044089800.014
protein modification by small protein conjugationGO:0032446790.014
response to organic substanceGO:00100332840.014
regulation of protein modification processGO:00313991120.014
positive regulation of rna biosynthetic processGO:19026802660.014
Yeast
embryonic pattern specificationGO:00098801740.014
dna dependent dna replicationGO:0006261170.014
dna damage checkpointGO:0000077780.014
regulation of cell projection organizationGO:0031344920.014
retina development in camera type eyeGO:006004140.013
blastoderm segmentationGO:00073501590.013
response to biotic stimulusGO:00096072940.013
cell proliferationGO:00082832990.013
response to external biotic stimulusGO:00432072930.013
mitotic dna damage checkpointGO:0044773740.013
negative regulation of neurogenesisGO:0050768530.013
methylationGO:0032259470.013
embryo development ending in birth or egg hatchingGO:00097921520.013
Worm
oxoacid metabolic processGO:00434361030.013
covalent chromatin modificationGO:00165691060.013
regulation of epithelial cell differentiationGO:003085640.013
response to other organismGO:00517072930.012
chaeta developmentGO:0022416970.012
vesicle mediated transportGO:00161923810.012
dna metabolic processGO:00062592270.012
catabolic processGO:00090564090.012
Yeast
cell maturationGO:00484691440.012
axon developmentGO:00615642970.012
eye morphogenesisGO:00485922600.012
carboxylic acid metabolic processGO:0019752920.012
regulation of innate immune responseGO:0045088710.012
intracellular transportGO:00469072280.012
regulation of multi organism processGO:00439001310.012
neural retina developmentGO:000340740.012
enzyme linked receptor protein signaling pathwayGO:00071671790.012
response to temperature stimulusGO:00092661060.012
response to organic cyclic compoundGO:0014070890.012
modification dependent protein catabolic processGO:0019941780.012
locomotory behaviorGO:00076261760.012
lateral inhibitionGO:00463312060.012
salivary gland morphogenesisGO:00074351450.012
mrna metabolic processGO:00160711240.012
Yeast
ncrna metabolic processGO:0034660430.012
dorsal ventral pattern formationGO:00099531330.012
dendrite morphogenesisGO:00488131990.012
organonitrogen compound metabolic processGO:19015643180.012
histone acetylationGO:0016573380.011
negative regulation of signalingGO:00230572190.011
ovipositionGO:0018991190.011
dorsal ventral pattern formation imaginal discGO:0007450510.011
regulation of cell cycle phase transitionGO:19019871300.011
immune system processGO:00023763470.011
neurological system processGO:00508773580.011
antimicrobial peptide productionGO:0002775460.011
positive regulation of catalytic activityGO:00430851180.011
internal peptidyl lysine acetylationGO:0018393380.011
regulation of mitotic cell cycle phase transitionGO:19019901300.011
jak stat cascadeGO:0007259490.011
heterochromatin organizationGO:0070828250.011
protein processingGO:0016485680.011
wing disc pattern formationGO:0035222660.011
cellular response to organic cyclic compoundGO:0071407320.011
notch signaling pathwayGO:00072191200.011
reproductive structure developmentGO:0048608740.011
morphogenesis of a polarized epitheliumGO:0001738930.011
cellular response to organic substanceGO:00713101320.011
sensory perception of painGO:001923340.011
intracellular receptor signaling pathwayGO:0030522190.011
regulation of erbb signaling pathwayGO:1901184420.011
purine ribonucleoside catabolic processGO:00461301120.010
wnt signaling pathwayGO:0016055980.010
regulation of anatomical structure sizeGO:00900661630.010
cell deathGO:00082192790.010
developmental growth involved in morphogenesisGO:0060560650.010
stem cell developmentGO:0048864790.010
anterior posterior pattern specificationGO:00099521360.010
defense response to other organismGO:00985422250.010
organelle fissionGO:00482853400.010
muscle cell differentiationGO:00426921030.010

Cdk8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.010
central nervous system diseaseDOID:33100.010
nervous system diseaseDOID:86300.010