Drosophila melanogaster

43 known processes

ko (Dmel_CG10573)

knockout

(Aliases: Dmel\CG10573,CG10573)

ko biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
wing disc morphogenesisGO:00074723440.224
neurological system processGO:00508773580.215
motor neuron axon guidanceGO:0008045580.201
locomotory behaviorGO:00076261760.198
chemotaxisGO:00069352490.158
appendage developmentGO:00487364010.149
post embryonic appendage morphogenesisGO:00351203850.147
axonogenesisGO:00074092900.139
appendage morphogenesisGO:00351073970.136
axon guidanceGO:00074112330.118
taxisGO:00423303040.116
response to oxidative stressGO:0006979860.114
axon developmentGO:00615642970.101
cell adhesion involved in heart morphogenesisGO:0061343120.093
cellular amino acid metabolic processGO:0006520610.090
neuron recognitionGO:00080381010.088
detection of stimulusGO:00516061560.084
sensory organ morphogenesisGO:00905962600.083
regulation of neurogenesisGO:00507671580.081
imaginal disc derived appendage morphogenesisGO:00351143950.079
hindbrain developmentGO:003090220.068
imaginal disc derived appendage developmentGO:00487373990.067
single organism behaviorGO:00447083910.063
adult behaviorGO:00305341370.061
sensory perceptionGO:00076001960.061
learningGO:0007612750.059
oxoacid metabolic processGO:00434361030.058
skeletal muscle fiber developmentGO:004874130.057
eye morphogenesisGO:00485922600.056
organelle fissionGO:00482853400.055
regulation of multicellular organismal developmentGO:20000264140.054
learning or memoryGO:00076111410.054
cell recognitionGO:00080371020.051
synaptic target recognitionGO:0008039450.048
cell adhesionGO:00071551360.047
small molecule metabolic processGO:00442813050.047
catabolic processGO:00090564090.046
cognitionGO:00508901410.046
eye developmentGO:00016543230.044
neuron projection guidanceGO:00974852410.044
organic acid metabolic processGO:00060821030.043
enzyme linked receptor protein signaling pathwayGO:00071671790.043
camera type eye developmentGO:004301040.042
synapse organizationGO:00508081960.042
response to oxygen containing compoundGO:19017002000.041
imaginal disc derived wing morphogenesisGO:00074763370.040
kidney developmentGO:000182230.040
adult locomotory behaviorGO:0008344760.039
molting cycle chitin based cuticleGO:0007591560.039
amine metabolic processGO:0009308120.039
carboxylic acid metabolic processGO:0019752920.039
regionalizationGO:00030024160.038
mesoderm developmentGO:0007498780.038
actin cytoskeleton organizationGO:00300362060.037
negative regulation of cell differentiationGO:00455961430.037
cell maturationGO:00484691440.037
regulation of gene expression epigeneticGO:00400291280.036
acetylcholine metabolic processGO:000829120.036
positive regulation of cell communicationGO:00106472500.035
forebrain developmentGO:003090020.035
response to lipopolysaccharideGO:003249640.034
tube morphogenesisGO:00352391910.033
positive regulation of response to stimulusGO:00485843230.033
embryonic morphogenesisGO:00485982060.032
nephron epithelium developmentGO:007200930.032
cellular amine metabolic processGO:0044106120.032
body morphogenesisGO:001017120.031
tube developmentGO:00352952440.030
nuclear divisionGO:00002803320.029
organonitrogen compound metabolic processGO:19015643180.029
positive regulation of macromolecule metabolic processGO:00106044050.029
positive regulation of cellular component organizationGO:00511301560.029
positive regulation of signalingGO:00230562430.029
regulation of tube size open tracheal systemGO:0035151430.028
response to radiationGO:00093141550.028
compound eye developmentGO:00487493070.028
regulation of cellular ketone metabolic processGO:001056530.028
photoreceptor cell axon guidanceGO:0072499230.028
photoreceptor cell differentiationGO:00465301700.027
regulation of developmental growthGO:00486381740.027
regulation of neuron differentiationGO:00456641030.027
cellular response to dna damage stimulusGO:00069742230.027
connective tissue developmentGO:006144830.027
response to nitrogen compoundGO:1901698900.027
apical junction assemblyGO:0043297320.026
eye photoreceptor cell differentiationGO:00017541450.026
skeletal muscle organ developmentGO:0060538480.026
retina development in camera type eyeGO:006004140.026
cellular protein modification processGO:00064644380.026
biological adhesionGO:00226101380.026
notch signaling pathwayGO:00072191200.025
cell proliferationGO:00082832990.025
regulation of nervous system developmentGO:00519602480.025
protein modification processGO:00362114380.025
negative regulation of multicellular organismal processGO:00512411420.024
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.024
gene silencingGO:00164581380.024
establishment of blood brain barrierGO:0060856160.024
eye photoreceptor cell developmentGO:0042462810.024
organic substance catabolic processGO:19015753080.023
cell migrationGO:00164772380.023
positive regulation of signal transductionGO:00099672230.023
acetylcholine catabolic processGO:000658110.023
positive regulation of cellular amine metabolic processGO:003324000.022
dorsal ventral pattern formationGO:00099531330.022
response to organic substanceGO:00100332840.022
chromatin silencingGO:0006342760.022
aromatic compound catabolic processGO:00194391660.022
regulation of intracellular signal transductionGO:19025312360.022
positive regulation of phosphate metabolic processGO:00459371390.022
response to organonitrogen compoundGO:0010243750.021
developmental maturationGO:00217001720.021
positive regulation of intracellular signal transductionGO:19025331160.021
imaginal disc derived wing hair organizationGO:0035317450.021
ras protein signal transductionGO:0007265880.021
nephron developmentGO:007200630.021
sensory perception of soundGO:0007605560.021
regulation of cytoskeleton organizationGO:0051493890.021
cellular catabolic processGO:00442483720.021
regulation of microtubule based processGO:0032886490.021
regulation of cellular component sizeGO:0032535980.021
negative regulation of nervous system developmentGO:0051961920.021
establishment of glial blood brain barrierGO:0060857140.020
cell projection assemblyGO:0030031940.020
compound eye photoreceptor cell differentiationGO:00017511400.020
actin filament organizationGO:00070151260.020
cell divisionGO:00513012480.020
negative regulation of signalingGO:00230572190.020
positive regulation of nitrogen compound metabolic processGO:00511733540.019
response to ethanolGO:0045471590.019
regulation of cell cycleGO:00517262910.019
synapse assemblyGO:00074161430.019
intracellular signal transductionGO:00355563000.019
regulation of response to stressGO:00801342000.019
regulation of cellular amine metabolic processGO:003323830.019
regulation of protein metabolic processGO:00512462560.019
negative regulation of nitrogen compound metabolic processGO:00511722650.019
hair cell differentiationGO:0035315470.019
phagocytosisGO:00069092150.019
positive regulation of transcription dna templatedGO:00458932660.018
negative regulation of macromolecule biosynthetic processGO:00105582700.018
positive regulation of cell motilityGO:200014730.018
nucleobase containing compound catabolic processGO:00346551650.018
sensory perception of mechanical stimulusGO:0050954720.018
muscle structure developmentGO:00610612240.018
telencephalon developmentGO:002153720.018
cell cell junction assemblyGO:0007043380.018
cellular ketone metabolic processGO:0042180240.018
establishment of localization in cellGO:00516494020.018
response to alcoholGO:0097305950.017
regulation of actin cytoskeleton organizationGO:0032956420.017
acetate ester metabolic processGO:190061920.017
negative regulation of gene expression epigeneticGO:0045814770.017
positive regulation of cellular component biogenesisGO:0044089800.017
salivary gland developmentGO:00074311620.017
spermatogenesisGO:00072832000.017
cell cell adhesion via plasma membrane adhesion moleculesGO:0098742260.017
eggshell formationGO:00307031050.017
gland developmentGO:00487321910.017
single organism biosynthetic processGO:00447112060.017
cellular response to ethanolGO:007136140.016
muscle organ developmentGO:00075171270.016
positive regulation of cellular biosynthetic processGO:00313283160.016
regulation of tube sizeGO:0035150460.016
g protein coupled receptor signaling pathwayGO:00071861360.016
negative regulation of nucleic acid templated transcriptionGO:19035072400.016
cellular macromolecule localizationGO:00707272200.016
detection of stimulus involved in sensory perceptionGO:0050906920.016
establishment or maintenance of cell polarityGO:00071631670.016
photoreceptor cell developmentGO:0042461960.016
morphogenesis of an epitheliumGO:00020092760.016
actin filament based processGO:00300292200.016
jak stat cascadeGO:0007259490.016
spinal cord developmentGO:002151010.016
chromatin modificationGO:00165681470.015
septate junction assemblyGO:0019991260.015
heart developmentGO:0007507820.015
negative regulation of response to stimulusGO:00485852580.015
regulation of molecular functionGO:00650092170.015
positive regulation of phosphorylationGO:0042327870.015
memoryGO:0007613940.015
organic substance transportGO:00717022570.015
anterior posterior pattern specificationGO:00099521360.015
glial cell differentiationGO:0010001350.015
regulation of cell differentiationGO:00455953020.015
immune response regulating signaling pathwayGO:000276420.015
multi multicellular organism processGO:00447061230.014
single organism carbohydrate metabolic processGO:0044723720.014
microtubule organizing center organizationGO:00310231680.014
negative regulation of gene expressionGO:00106293870.014
rhythmic processGO:00485111060.014
positive regulation of neuron differentiationGO:0045666260.014
gliogenesisGO:0042063800.014
outflow tract morphogenesisGO:000315140.014
negative regulation of cell communicationGO:00106482230.014
peptidyl amino acid modificationGO:00181931050.014
protein complex biogenesisGO:00702712010.014
response to abiotic stimulusGO:00096283410.014
regulation of cellular component biogenesisGO:00440872010.014
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.014
developmental growth involved in morphogenesisGO:0060560650.014
olfactory learningGO:0008355560.014
negative regulation of cellular biosynthetic processGO:00313272770.013
protein phosphorylationGO:00064681690.013
regulation of localizationGO:00328792750.013
carbohydrate derivative metabolic processGO:19011352170.013
localization of cellGO:00516742570.013
regulation of anatomical structure sizeGO:00900661630.013
inorganic ion transmembrane transportGO:0098660730.013
neurotransmitter metabolic processGO:004213320.013
single organismal cell cell adhesionGO:0016337450.013
limb morphogenesisGO:003510810.013
regulation of behaviorGO:0050795750.013
lateral inhibitionGO:00463312060.013
regulation of microtubule polymerization or depolymerizationGO:0031110270.013
cell deathGO:00082192790.013
lipopolysaccharide mediated signaling pathwayGO:003166310.013
columnar cuboidal epithelial cell differentiationGO:00020652560.013
cell cell signaling involved in cell fate commitmentGO:00451682100.013
limb developmentGO:006017310.013
cellular component assembly involved in morphogenesisGO:00109271510.013
negative regulation of nucleobase containing compound metabolic processGO:00459342610.013
homeostatic processGO:00425921990.013
response to monosaccharideGO:003428440.013
molting cycleGO:0042303560.013
small gtpase mediated signal transductionGO:0007264880.013
regulation of neuron projection developmentGO:0010975690.013
axis specificationGO:00097981670.013
endocytosisGO:00068973100.012
regulation of protein modification processGO:00313991120.012
negative regulation of rna biosynthetic processGO:19026792400.012
regulation of organelle organizationGO:00330431960.012
imaginal disc pattern formationGO:0007447910.012
vesicle mediated transportGO:00161923810.012
microtubule polymerization or depolymerizationGO:0031109390.012
positive regulation of peptidyl tyrosine phosphorylationGO:005073140.012
small molecule catabolic processGO:0044282210.012
single organism catabolic processGO:00447122280.012
organic cyclic compound catabolic processGO:19013611680.012
kidney epithelium developmentGO:007207330.012
organelle assemblyGO:00709251980.012
purine containing compound metabolic processGO:00725211550.012
negative regulation of rna metabolic processGO:00512532510.012
regulation of epithelial cell differentiationGO:003085640.012
cellular response to molecule of bacterial originGO:007121930.012
kidney morphogenesisGO:006099330.012
striated muscle cell differentiationGO:0051146900.012
chromatin organizationGO:00063252070.012
regulation of cellular protein metabolic processGO:00322682430.012
heterophilic cell cell adhesion via plasma membrane cell adhesion moleculesGO:000715780.012
cell cell junction organizationGO:0045216550.012
regulation of membrane potentialGO:0042391350.012
positive regulation of molecular functionGO:00440931360.012
nucleoside phosphate metabolic processGO:00067531620.012
negative regulation of mitotic cell cycle phase transitionGO:19019911030.012
substrate adhesion dependent cell spreadingGO:003444620.012
cellular response to lipopolysaccharideGO:007122230.012
positive regulation of nervous system developmentGO:0051962690.011
negative regulation of cell developmentGO:0010721620.011
neuromuscular junction developmentGO:00075281490.011
gland morphogenesisGO:00226121450.011
cellular response to organonitrogen compoundGO:0071417360.011
organophosphate metabolic processGO:00196371950.011
cellular response to nitrogen compoundGO:1901699510.011
cellular nitrogen compound catabolic processGO:00442701650.011
regulation of catabolic processGO:00098941700.011
reproductive system developmentGO:0061458740.011
macromolecular complex assemblyGO:00650032560.011
peptidyl threonine phosphorylationGO:001810720.011
maintenance of locationGO:0051235730.011
regulation of gene silencingGO:0060968630.011
tripartite regional subdivisionGO:00073511030.011
carbohydrate metabolic processGO:0005975820.011
regulation of cell shapeGO:00083601130.011
regulation of synapse organizationGO:00508071100.011
chromosome organizationGO:00512763600.011
nephron morphogenesisGO:007202830.011
negative regulation of biosynthetic processGO:00098902770.011
positive regulation of nucleobase containing compound metabolic processGO:00459353320.011
regulation of microtubule cytoskeleton organizationGO:0070507410.011
regulation of cell cycle processGO:00105641810.011
positive regulation of developmental processGO:00510941430.011
axonal defasciculationGO:0007414120.011
regulation of cell proliferationGO:00421271630.011
glial cell developmentGO:0021782270.011
salivary gland morphogenesisGO:00074351450.011
extrinsic apoptotic signaling pathwayGO:009719110.011
cytoskeleton dependent cytokinesisGO:0061640810.011
positive regulation of cellular amino acid metabolic processGO:004576400.011
sex differentiationGO:0007548810.011
response to other organismGO:00517072930.011
cell junction organizationGO:0034330570.010
response to glucoseGO:000974920.010
formation of anatomical boundaryGO:0048859370.010
regulation of transcription from rna polymerase ii promoterGO:00063573780.010
embryo development ending in birth or egg hatchingGO:00097921520.010
anatomical structure homeostasisGO:0060249970.010
positive regulation of multicellular organismal processGO:00512401430.010
developmental programmed cell deathGO:00106231380.010
positive regulation of nucleic acid templated transcriptionGO:19035082660.010
cranial nerve developmentGO:002154510.010
intracellular transportGO:00469072280.010
regulation of glial cell differentiationGO:004568510.010
compound eye photoreceptor developmentGO:0042051780.010

ko disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.040
nervous system diseaseDOID:86300.013
bone development diseaseDOID:008000600.012
connective tissue diseaseDOID:6500.012
musculoskeletal system diseaseDOID:1700.012
bone diseaseDOID:008000100.012
sensory system diseaseDOID:005015500.011
disease of metabolismDOID:001466700.010