Drosophila melanogaster

36 known processes

Hcs (Dmel_CG14670)

Holocarboxylase synthetase

(Aliases: HCS,Dmel\CG14670,CG14670,NEST:bs27h05)

Hcs biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein modification processGO:00362114380.055
organonitrogen compound metabolic processGO:19015643180.032
organic substance catabolic processGO:19015753080.032
carbohydrate derivative metabolic processGO:19011352170.032
nucleobase containing compound catabolic processGO:00346551650.032
cellular catabolic processGO:00442483720.032
heterocycle catabolic processGO:00467001660.030
ribonucleoside catabolic processGO:00424541120.030
nucleoside phosphate metabolic processGO:00067531620.029
regulation of cellular amine metabolic processGO:003323830.029
aromatic compound catabolic processGO:00194391660.028
small molecule metabolic processGO:00442813050.028
negative regulation of gene expressionGO:00106293870.028
cellular nitrogen compound catabolic processGO:00442701650.027
imaginal disc derived appendage developmentGO:00487373990.026
purine ribonucleotide catabolic processGO:00091541090.026
purine containing compound metabolic processGO:00725211550.025
post embryonic appendage morphogenesisGO:00351203850.025
nucleoside phosphate catabolic processGO:19012921100.025
regulation of anatomical structure sizeGO:00900661630.025
positive regulation of nucleobase containing compound metabolic processGO:00459353320.025
appendage morphogenesisGO:00351073970.024
ribonucleotide metabolic processGO:00092591450.024
neurological system processGO:00508773580.024
morphogenesis of an epitheliumGO:00020092760.024
organic cyclic compound catabolic processGO:19013611680.023
small gtpase mediated signal transductionGO:0007264880.023
regulation of intracellular signal transductionGO:19025312360.023
regulation of catabolic processGO:00098941700.023
regionalizationGO:00030024160.023
ras protein signal transductionGO:0007265880.023
compound eye developmentGO:00487493070.022
cellular protein modification processGO:00064644380.022
single organism catabolic processGO:00447122280.022
purine nucleotide catabolic processGO:00061951090.022
phagocytosisGO:00069092150.022
imaginal disc derived wing morphogenesisGO:00074763370.022
carboxylic acid metabolic processGO:0019752920.022
phosphorylationGO:00163102940.022
amine metabolic processGO:0009308120.022
intracellular signal transductionGO:00355563000.021
organophosphate metabolic processGO:00196371950.021
appendage developmentGO:00487364010.021
ribonucleoside metabolic processGO:00091191270.021
protein complex biogenesisGO:00702712010.021
catabolic processGO:00090564090.021
positive regulation of nitrogen compound metabolic processGO:00511733540.021
single organism behaviorGO:00447083910.021
vesicle mediated transportGO:00161923810.021
purine nucleotide metabolic processGO:00061631460.021
body morphogenesisGO:001017120.021
purine ribonucleoside catabolic processGO:00461301120.021
organonitrogen compound biosynthetic processGO:19015661170.021
single organism biosynthetic processGO:00447112060.020
cellular amine metabolic processGO:0044106120.020
negative regulation of response to stimulusGO:00485852580.020
regulation of cellular catabolic processGO:00313291570.020
epithelial cell developmentGO:00020642740.020
connective tissue developmentGO:006144830.020
regulation of ras protein signal transductionGO:0046578930.020
negative regulation of cellular metabolic processGO:00313243820.020
regulation of molecular functionGO:00650092170.020
transcription from rna polymerase ii promoterGO:00063663680.020
regulation of cellular component biogenesisGO:00440872010.020
positive regulation of cellular biosynthetic processGO:00313283160.020
purine ribonucleoside metabolic processGO:00461281270.020
regulation of small gtpase mediated signal transductionGO:0051056930.019
nucleoside triphosphate metabolic processGO:00091411200.019
nucleoside triphosphate catabolic processGO:00091431080.019
regulation of catalytic activityGO:00507901850.019
purine nucleoside triphosphate catabolic processGO:00091461080.019
purine nucleoside catabolic processGO:00061521120.019
regulation of phosphorus metabolic processGO:00511742100.019
biological adhesionGO:00226101380.019
cellular amino acid metabolic processGO:0006520610.019
endocytosisGO:00068973100.019
endomembrane system organizationGO:00102561190.019
wing disc morphogenesisGO:00074723440.019
camera type eye developmentGO:004301040.018
columnar cuboidal epithelial cell differentiationGO:00020652560.018
regulation of nucleotide catabolic processGO:0030811480.018
gland developmentGO:00487321910.018
response to organic substanceGO:00100332840.018
developmental growthGO:00485892800.018
regulation of localizationGO:00328792750.018
eye morphogenesisGO:00485922600.018
purine ribonucleoside triphosphate catabolic processGO:00092071080.018
regulation of cellular ketone metabolic processGO:001056530.018
eye developmentGO:00016543230.018
organonitrogen compound catabolic processGO:19015651280.018
purine ribonucleoside triphosphate metabolic processGO:00092051190.018
purine ribonucleotide metabolic processGO:00091501450.018
positive regulation of cell communicationGO:00106472500.018
organic acid metabolic processGO:00060821030.017
open tracheal system developmentGO:00074242040.017
gene silencingGO:00164581380.017
ribonucleotide catabolic processGO:00092611090.017
protein phosphorylationGO:00064681690.017
macromolecule catabolic processGO:00090571610.017
cell deathGO:00082192790.017
nucleobase containing small molecule metabolic processGO:00550861740.017
regulation of transcription from rna polymerase ii promoterGO:00063573780.017
ribonucleoside triphosphate metabolic processGO:00091991190.017
nucleoside catabolic processGO:00091641120.017
negative regulation of nucleobase containing compound metabolic processGO:00459342610.017
salivary gland developmentGO:00074311620.017
positive regulation of catalytic activityGO:00430851180.017
regulation of transportGO:00510491810.017
axonogenesisGO:00074092900.017
deathGO:00162652840.017
regulation of cellular amino acid metabolic processGO:000652100.016
ribose phosphate metabolic processGO:00196931450.016
negative regulation of cellular biosynthetic processGO:00313272770.016
ribonucleoside triphosphate catabolic processGO:00092031080.016
regulation of programmed cell deathGO:00430671520.016
gtp catabolic processGO:0006184720.016
negative regulation of signal transductionGO:00099682060.016
golgi organizationGO:0007030660.016
rna processingGO:00063961470.016
nucleotide catabolic processGO:00091661090.016
positive regulation of phosphorus metabolic processGO:00105621390.016
response to abiotic stimulusGO:00096283410.016
regulation of cellular component sizeGO:0032535980.016
sensory organ morphogenesisGO:00905962600.016
embryonic pattern specificationGO:00098801740.016
neuron projection guidanceGO:00974852410.016
glycosyl compound metabolic processGO:19016571270.016
response to lipopolysaccharideGO:003249640.015
compound eye morphogenesisGO:00017452490.015
oxoacid metabolic processGO:00434361030.015
segmentationGO:00352822070.015
regulation of protein metabolic processGO:00512462560.015
imaginal disc derived appendage morphogenesisGO:00351143950.015
positive regulation of cellular catabolic processGO:0031331950.015
positive regulation of nucleoside metabolic processGO:0045979470.015
positive regulation of hydrolase activityGO:0051345780.015
regulation of response to stressGO:00801342000.015
positive regulation of purine nucleotide metabolic processGO:1900544550.015
respiratory system developmentGO:00605412130.015
gtp metabolic processGO:0046039720.015
nucleoside metabolic processGO:00091161270.015
positive regulation of molecular functionGO:00440931360.015
organophosphate catabolic processGO:00464341120.015
carbohydrate metabolic processGO:0005975820.014
guanosine containing compound catabolic processGO:1901069740.014
cell proliferationGO:00082832990.014
forebrain developmentGO:003090020.014
negative regulation of nitrogen compound metabolic processGO:00511722650.014
columnar cuboidal epithelial cell developmentGO:00020662490.014
response to oxygen containing compoundGO:19017002000.014
regulation of ras gtpase activityGO:0032318380.014
positive regulation of cell migrationGO:003033520.014
cellular ketone metabolic processGO:0042180240.014
response to starvationGO:0042594970.014
positive regulation of catabolic processGO:00098961050.014
negative regulation of developmental processGO:00510932010.014
regulation of multicellular organismal developmentGO:20000264140.014
salivary gland morphogenesisGO:00074351450.014
actin filament based processGO:00300292200.014
positive regulation of gene expressionGO:00106282900.014
gland morphogenesisGO:00226121450.014
programmed cell deathGO:00125012570.014
establishment of localization in cellGO:00516494020.014
photoreceptor cell developmentGO:0042461960.014
positive regulation of cellular amine metabolic processGO:003324000.014
negative regulation of rna metabolic processGO:00512532510.014
positive regulation of macromolecule metabolic processGO:00106044050.014
compound eye photoreceptor cell differentiationGO:00017511400.014
positive regulation of rna metabolic processGO:00512542710.014
regulation of mitotic cell cycleGO:00073461900.014
actin cytoskeleton organizationGO:00300362060.014
posttranscriptional regulation of gene expressionGO:00106081450.014
positive regulation of biosynthetic processGO:00098913160.014
cuticle developmentGO:0042335860.014
positive regulation of response to stimulusGO:00485843230.014
taxisGO:00423303040.013
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.013
response to extracellular stimulusGO:00099911160.013
regulation of anatomical structure morphogenesisGO:00226032420.013
locomotory behaviorGO:00076261760.013
single organism carbohydrate metabolic processGO:0044723720.013
positive regulation of ras gtpase activityGO:0032320360.013
glycosyl compound catabolic processGO:19016581120.013
organic substance transportGO:00717022570.013
protein complex assemblyGO:00064612000.013
tissue morphogenesisGO:00487292970.013
negative regulation of biosynthetic processGO:00098902770.013
blastoderm segmentationGO:00073501590.013
macromolecular complex assemblyGO:00650032560.013
cellular response to chemical stimulusGO:00708871990.013
positive regulation of cell motilityGO:200014730.013
regulation of cell substrate adhesionGO:001081020.012
regulation of gtp catabolic processGO:0033124440.012
ovarian follicle cell developmentGO:00307072480.012
negative regulation of multicellular organismal processGO:00512411420.012
positive regulation of nucleic acid templated transcriptionGO:19035082660.012
regulation of phosphate metabolic processGO:00192202100.012
retina development in camera type eyeGO:006004140.012
purine nucleoside metabolic processGO:00422781270.012
autophagic cell deathGO:0048102830.012
negative regulation of cell communicationGO:00106482230.012
exocrine system developmentGO:00352721620.012
eggshell formationGO:00307031050.012
positive regulation of rna biosynthetic processGO:19026802660.012
negative regulation of nervous system developmentGO:0051961920.012
positive regulation of phosphate metabolic processGO:00459371390.012
cellular component assembly involved in morphogenesisGO:00109271510.012
epithelial cell differentiationGO:00308553220.012
establishment of vesicle localizationGO:0051650510.012
negative regulation of signalingGO:00230572190.012
defense responseGO:00069523000.012
histolysisGO:00075591020.012
cell cycle phase transitionGO:00447701400.012
regulation of gene silencingGO:0060968630.012
nucleotide metabolic processGO:00091171610.012
regulation of purine nucleotide catabolic processGO:0033121480.012
protein modification by small protein conjugation or removalGO:00706471060.012
regulation of mitotic cell cycle phase transitionGO:19019901300.012
pigmentationGO:0043473750.012
neuron recognitionGO:00080381010.012
sensory perceptionGO:00076001960.012
positive regulation of nucleotide metabolic processGO:0045981550.012
homeostatic processGO:00425921990.012
xenobiotic catabolic processGO:004217810.012
developmental programmed cell deathGO:00106231380.012
regulation of organelle organizationGO:00330431960.012
protein localizationGO:00081042840.012
positive regulation of gtpase activityGO:0043547430.012
positive regulation of nucleotide catabolic processGO:0030813460.012
steroid catabolic processGO:000670610.012
chemotaxisGO:00069352490.012
peptidyl amino acid modificationGO:00181931050.012
purine nucleoside triphosphate metabolic processGO:00091441190.012
agingGO:00075681430.012
telencephalon developmentGO:002153720.012
synapse organizationGO:00508081960.012
photoreceptor cell differentiationGO:00465301700.012
purine containing compound catabolic processGO:00725231120.011
regulation of epithelial cell proliferationGO:005067840.011
vesicle organizationGO:0016050440.011
growthGO:00400073590.011
regulation of cell deathGO:00109411730.011
regulation of gtpase activityGO:0043087440.011
positive regulation of signal transductionGO:00099672230.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.011
regulation of hydrolase activityGO:0051336970.011
enzyme linked receptor protein signaling pathwayGO:00071671790.011
cellular response to organic substanceGO:00713101320.011
tissue deathGO:00162711020.011
organelle fissionGO:00482853400.011
regulation of cellular protein metabolic processGO:00322682430.011
defense response to bacteriumGO:00427421780.011
embryonic axis specificationGO:00005781070.011
negative regulation of macromolecule biosynthetic processGO:00105582700.011
anion homeostasisGO:005508130.011
negative regulation of gene expression epigeneticGO:0045814770.011
camera type eye morphogenesisGO:004859320.011
eye photoreceptor cell differentiationGO:00017541450.011
lateral inhibitionGO:00463312060.011
cellular response to dna damage stimulusGO:00069742230.011
negative regulation of cell differentiationGO:00455961430.011
actin filament organizationGO:00070151260.011
hindbrain developmentGO:003090220.011
salivary gland histolysisGO:0035070880.011
axon guidanceGO:00074112330.011
proteolysisGO:00065081920.011
pigment metabolic processGO:0042440840.011
regulation of gene expression epigeneticGO:00400291280.011
limb developmentGO:006017310.011
guanosine containing compound metabolic processGO:1901068740.011
cellular response to starvationGO:0009267610.011
imaginal disc derived leg morphogenesisGO:0007480800.011
hormone catabolic processGO:004244730.011
response to bacteriumGO:00096171980.011
regulation of cell cycleGO:00517262910.011
wnt signaling pathwayGO:0016055980.011
organelle assemblyGO:00709251980.011
central nervous system developmentGO:00074172010.011
axon developmentGO:00615642970.011
regulation of microtubule polymerization or depolymerizationGO:0031110270.011
regulation of nucleoside metabolic processGO:0009118500.011
negative regulation of nucleic acid templated transcriptionGO:19035072400.010
erbb signaling pathwayGO:0038127580.010
axis specificationGO:00097981670.010
response to hexoseGO:000974630.010
negative regulation of transcription dna templatedGO:00458922370.010
peptidyl threonine modificationGO:001821030.010
dorsal ventral pattern formationGO:00099531330.010
cell recognitionGO:00080371020.010
response to external biotic stimulusGO:00432072930.010
embryonic morphogenesisGO:00485982060.010
positive regulation of peptidyl tyrosine phosphorylationGO:005073140.010
response to nitrogen compoundGO:1901698900.010
response to monosaccharideGO:003428440.010
response to other organismGO:00517072930.010
cellular macromolecule catabolic processGO:00442651360.010
positive regulation of cellular amino acid metabolic processGO:004576400.010
positive regulation of signalingGO:00230562430.010
positive regulation of cell deathGO:0010942690.010

Hcs disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.044
nervous system diseaseDOID:86300.025
cardiovascular system diseaseDOID:128700.012
central nervous system diseaseDOID:33100.012
musculoskeletal system diseaseDOID:1700.011
neurodegenerative diseaseDOID:128900.011
disease of metabolismDOID:001466700.011
disease of cellular proliferationDOID:1456600.011