Drosophila melanogaster

11 known processes

Sema-1b (Dmel_CG6446)

CG6446 gene product from transcript CG6446-RA

(Aliases: Dmel\CG6446,Sema 1b,BcDNA:GH03186,D-semaIII,Sema1b,sema-III,CG6446,Sema III)

Sema-1b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
taxisGO:00423303040.853
Zebrafish Rat Fly
morphogenesis of an epitheliumGO:00020092760.813
axon developmentGO:00615642970.761
Rat Fly
axonogenesisGO:00074092900.667
Rat Fly
immune response activating signal transductionGO:000275720.596
neuron projection guidanceGO:00974852410.550
Rat Fly
cell growthGO:00160491080.518
defense response to virusGO:0051607230.510
cellular protein modification processGO:00064644380.494
regulation of synapse organizationGO:00508071100.492
axon guidanceGO:00074112330.398
Rat Fly
immune response regulating signaling pathwayGO:000276420.380
regulation of cell morphogenesisGO:00226041630.347
Fly
positive regulation of response to stimulusGO:00485843230.344
developmental growthGO:00485892800.338
morphogenesis of embryonic epitheliumGO:0016331940.335
protein modification processGO:00362114380.324
regulation of intracellular signal transductionGO:19025312360.320
regionalizationGO:00030024160.311
positive regulation of signal transductionGO:00099672230.311
negative regulation of response to stimulusGO:00485852580.304
response to organic substanceGO:00100332840.281
response to virusGO:0009615280.278
synapse assemblyGO:00074161430.271
Fly
chemotaxisGO:00069352490.260
Zebrafish Rat Fly
activation of immune responseGO:000225350.251
immune responseGO:00069552460.246
negative regulation of cell communicationGO:00106482230.236
tissue morphogenesisGO:00487292970.232
phosphorylationGO:00163102940.230
photoreceptor cell axon guidanceGO:0072499230.227
positive regulation of cellular component organizationGO:00511301560.224
regulation of response to external stimulusGO:00321011150.211
Fly
embryo development ending in birth or egg hatchingGO:00097921520.208
synapse organizationGO:00508081960.208
Fly
regulation of synapse structure and activityGO:00508031280.202
positive regulation of intracellular signal transductionGO:19025331160.186
positive regulation of cell communicationGO:00106472500.183
neuron projection extensionGO:1990138320.180
intracellular signal transductionGO:00355563000.177
protein phosphorylationGO:00064681690.176
negative regulation of signal transductionGO:00099682060.170
cell motilityGO:00488702510.166
regulation of immune responseGO:00507761180.164
biological adhesionGO:00226101380.160
regulation of neuron projection developmentGO:0010975690.158
Fly
regulation of phosphorylationGO:00423251470.152
regulation of response to stressGO:00801342000.151
Fly
columnar cuboidal epithelial cell developmentGO:00020662490.149
positive regulation of multicellular organismal processGO:00512401430.144
microtubule organizing center organizationGO:00310231680.143
negative regulation of gene expressionGO:00106293870.131
developmental growth involved in morphogenesisGO:0060560650.131
negative regulation of signalingGO:00230572190.131
dendrite developmentGO:00163582040.128
Fly
negative regulation of response to external stimulusGO:0032102220.128
positive regulation of immune responseGO:0050778630.127
appendage developmentGO:00487364010.127
positive regulation of signalingGO:00230562430.126
regulation of immune effector processGO:0002697520.125
positive regulation of macromolecule metabolic processGO:00106044050.117
regulation of neurogenesisGO:00507671580.111
Fly
growthGO:00400073590.110
regulation of nervous system developmentGO:00519602480.108
Fly
cardiovascular system developmentGO:0072358820.107
embryonic pattern specificationGO:00098801740.105
endocytosisGO:00068973100.105
photoreceptor cell differentiationGO:00465301700.098
cell recognitionGO:00080371020.097
Fly
compound eye photoreceptor cell differentiationGO:00017511400.097
cell deathGO:00082192790.095
ovarian follicle cell developmentGO:00307072480.093
regulation of synapse assemblyGO:0051963940.089
gland developmentGO:00487321910.089
Fly
regulation of programmed cell deathGO:00430671520.087
cellular protein localizationGO:00346131600.087
axon extensionGO:0048675320.085
regulation of protein metabolic processGO:00512462560.084
developmental cell growthGO:0048588520.084
semaphorin plexin signaling pathway involved in regulation of photoreceptor cell axon guidanceGO:200030520.082
Fly
actin filament based processGO:00300292200.080
compound eye photoreceptor developmentGO:0042051780.080
immune effector processGO:0002252980.079
innate immune responseGO:00450871440.079
positive regulation of protein metabolic processGO:00512471280.079
regulation of growthGO:00400082330.078
mapk cascadeGO:00001651070.077
response to external biotic stimulusGO:00432072930.075
cellular catabolic processGO:00442483720.072
chromosome organizationGO:00512763600.072
columnar cuboidal epithelial cell differentiationGO:00020652560.071
homeostatic processGO:00425921990.071
cell adhesionGO:00071551360.070
negative regulation of immune system processGO:0002683500.070
cytoplasmic transportGO:00164821300.070
regulation of behaviorGO:0050795750.068
Fly
eye photoreceptor cell differentiationGO:00017541450.068
regulation of response to biotic stimulusGO:0002831630.065
regulation of cell developmentGO:00602842150.063
Fly
segmentationGO:00352822070.063
body morphogenesisGO:001017120.062
posttranscriptional gene silencingGO:0016441460.059
olfactory bulb axon guidanceGO:007167830.059
Fly
single organism cellular localizationGO:19025801800.058
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.058
posttranscriptional gene silencing by rnaGO:0035194450.058
deathGO:00162652840.057
chromosome segregationGO:00070591570.057
single organismal cell cell adhesionGO:0016337450.057
programmed cell deathGO:00125012570.057
regulation of defense responseGO:00313471020.057
cellular response to chemical stimulusGO:00708871990.056
circulatory system developmentGO:0072359820.056
transcription from rna polymerase ii promoterGO:00063663680.056
oxoacid metabolic processGO:00434361030.055
regulation of neuron differentiationGO:00456641030.054
Fly
protein transportGO:00150311550.054
immune system processGO:00023763470.054
positive regulation of macromolecule biosynthetic processGO:00105572830.053
positive regulation of nitrogen compound metabolic processGO:00511733540.053
positive regulation of transcription dna templatedGO:00458932660.052
response to abiotic stimulusGO:00096283410.052
Fly
positive regulation of nucleic acid templated transcriptionGO:19035082660.052
positive regulation of programmed cell deathGO:0043068620.052
positive regulation of nervous system developmentGO:0051962690.051
posttranscriptional regulation of gene expressionGO:00106081450.049
regulation of cell differentiationGO:00455953020.049
Fly
single organism biosynthetic processGO:00447112060.049
organic substance catabolic processGO:19015753080.049
embryonic axis specificationGO:00005781070.049
germ cell migrationGO:0008354430.048
extracellular structure organizationGO:0043062460.047
positive regulation of rna biosynthetic processGO:19026802660.047
regulation of cell morphogenesis involved in differentiationGO:0010769610.047
Fly
respiratory system developmentGO:00605412130.046
positive regulation of nucleobase containing compound metabolic processGO:00459353320.044
regulation of immune system processGO:00026821760.044
localization of cellGO:00516742570.044
protein catabolic processGO:00301631010.043
positive regulation of cellular amino acid metabolic processGO:004576400.043
carboxylic acid metabolic processGO:0019752920.042
response to other organismGO:00517072930.042
negative regulation of cellular metabolic processGO:00313243820.042
digestive system developmentGO:00551231490.042
signal transduction by phosphorylationGO:00230141070.041
appendage morphogenesisGO:00351073970.041
enzyme linked receptor protein signaling pathwayGO:00071671790.041
lipid metabolic processGO:00066291210.040
cellular macromolecule localizationGO:00707272200.040
chromatin organizationGO:00063252070.039
cell migrationGO:00164772380.039
regulation of multi organism processGO:00439001310.039
positive regulation of cellular component biogenesisGO:0044089800.039
regulation of apoptotic processGO:00429811300.039
epithelial cell migrationGO:00106311480.039
small molecule metabolic processGO:00442813050.039
positive regulation of cysteine type endopeptidase activityGO:2001056240.039
epithelium migrationGO:00901321480.038
blastoderm segmentationGO:00073501590.038
compound eye developmentGO:00487493070.038
axonal defasciculationGO:0007414120.038
regulation of cellular protein metabolic processGO:00322682430.037
regulation of anatomical structure sizeGO:00900661630.037
Fly
single organism intracellular transportGO:19025822070.037
positive regulation of apoptotic processGO:0043065470.037
regulation of cysteine type endopeptidase activityGO:2000116270.037
regulation of cell projection organizationGO:0031344920.037
Fly
positive regulation of developmental processGO:00510941430.036
single organism behaviorGO:00447083910.036
Fly
ameboidal type cell migrationGO:00016671510.035
photoreceptor cell developmentGO:0042461960.035
response to endogenous stimulusGO:00097191190.035
eye developmentGO:00016543230.035
response to biotic stimulusGO:00096072940.035
nuclear divisionGO:00002803320.034
regulation of mitotic cell cycleGO:00073461900.034
organic acid metabolic processGO:00060821030.034
positive regulation of immune system processGO:0002684680.034
innate immune response activating signal transductionGO:000275820.033
organonitrogen compound metabolic processGO:19015643180.033
regulation of mapk cascadeGO:0043408920.033
apoptotic processGO:00069151590.033
apoptotic signaling pathwayGO:0097190270.032
protein localizationGO:00081042840.032
ovarian follicle cell migrationGO:00072971210.031
cellular amine metabolic processGO:0044106120.031
proteolysisGO:00065081920.031
activation of innate immune responseGO:000221840.031
positive regulation of cellular biosynthetic processGO:00313283160.030
multi organism behaviorGO:00517051750.030
limb developmentGO:006017310.029
spermatid differentiationGO:00485151140.029
humoral immune responseGO:00069591170.029
regulation of cellular component biogenesisGO:00440872010.029
central nervous system developmentGO:00074172010.029
Fly
positive regulation of rna metabolic processGO:00512542710.029
positive regulation of cellular protein metabolic processGO:00322701180.028
forebrain developmentGO:003090020.028
regulation of organ morphogenesisGO:2000027780.028
regulation of transcription from rna polymerase ii promoterGO:00063573780.028
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.028
regulation of protein modification processGO:00313991120.028
regulation of axon extension involved in axon guidanceGO:004884140.027
defense responseGO:00069523000.027
amine metabolic processGO:0009308120.027
cellular response to peptide hormone stimulusGO:0071375280.026
tube developmentGO:00352952440.026
macromolecular complex assemblyGO:00650032560.026
regulation of cellular response to stressGO:0080135890.026
Fly
nuclear transportGO:0051169720.026
regulation of molecular functionGO:00650092170.026
regulation of phosphorus metabolic processGO:00511742100.026
eye morphogenesisGO:00485922600.025
peptidyl threonine phosphorylationGO:001810720.025
modification dependent macromolecule catabolic processGO:0043632790.024
cell divisionGO:00513012480.024
regulation of protein phosphorylationGO:0001932640.024
epithelial tube morphogenesisGO:0060562880.024
vesicle mediated transportGO:00161923810.024
neurological system processGO:00508773580.024
Fly
ras protein signal transductionGO:0007265880.024
positive regulation of growthGO:0045927750.024
protein targeting to nucleusGO:0044744510.024
neuron recognitionGO:00080381010.023
Fly
somatic muscle developmentGO:0007525660.023
mesenchymal cell differentiationGO:004876210.023
positive regulation of cellular amine metabolic processGO:003324000.023
intracellular transportGO:00469072280.023
catabolic processGO:00090564090.023
cellular macromolecule catabolic processGO:00442651360.023
endomembrane system organizationGO:00102561190.023
negative regulation of cell deathGO:0060548810.023
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.023
mrna catabolic processGO:0006402330.022
single organism nuclear importGO:1902593510.022
regulation of developmental growthGO:00486381740.022
positive regulation of proteolysisGO:0045862520.022
macromolecule catabolic processGO:00090571610.021
regulation of anatomical structure morphogenesisGO:00226032420.021
Fly
nucleocytoplasmic transportGO:0006913720.021
post embryonic appendage morphogenesisGO:00351203850.021
activation of protein kinase activityGO:0032147120.021
cellular response to organic cyclic compoundGO:0071407320.021
response to oxygen containing compoundGO:19017002000.020
gene silencing by rnaGO:0031047570.020
developmental maturationGO:00217001720.020
cellular ketone metabolic processGO:0042180240.020
embryonic morphogenesisGO:00485982060.020
phagocytosisGO:00069092150.020
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.020
heart developmentGO:0007507820.020
tissue migrationGO:00901301550.020
single organism membrane organizationGO:0044802930.020
zymogen activationGO:0031638200.020
regulation of bmp signaling pathwayGO:0030510230.020
cellular response to dna damage stimulusGO:00069742230.020
Fly
regulation of cell cycle processGO:00105641810.020
cellular response to nitrogen compoundGO:1901699510.020
protein acylationGO:0043543420.019
cell junction assemblyGO:0034329420.019
actin cytoskeleton reorganizationGO:0031532220.019
cellular response to organic substanceGO:00713101320.019
negative regulation of intracellular signal transductionGO:1902532570.018
imaginal disc derived appendage developmentGO:00487373990.018
positive regulation of gene expressionGO:00106282900.018
cellular response to endogenous stimulusGO:0071495800.018
mating behaviorGO:00076171060.018
positive regulation of phosphorus metabolic processGO:00105621390.018
regulation of cell deathGO:00109411730.018
negative regulation of programmed cell deathGO:0043069720.018
sensory organ morphogenesisGO:00905962600.018
regulation of axon extensionGO:003051680.017
establishment of protein localizationGO:00451841630.017
positive regulation of cell deathGO:0010942690.017
regulation of phosphate metabolic processGO:00192202100.017
open tracheal system developmentGO:00074242040.017
nephron developmentGO:007200630.017
cellular response to oxygen containing compoundGO:1901701790.017
motor neuron axon guidanceGO:0008045580.017
Fly
negative regulation of protein metabolic processGO:0051248850.017
compound eye morphogenesisGO:00017452490.016
ubiquitin dependent protein catabolic processGO:0006511780.016
salivary gland developmentGO:00074311620.016
Fly
dendrite morphogenesisGO:00488131990.016
Fly
regulation of innate immune responseGO:0045088710.016
dna metabolic processGO:00062592270.016
exocrine system developmentGO:00352721620.016
Fly
response to growth factorGO:0070848310.016
response to protozoanGO:000156230.016
epithelial cell developmentGO:00020642740.016
organic substance transportGO:00717022570.016
pigment metabolic processGO:0042440840.016
negative regulation of multi organism processGO:0043901290.015
regulation of protein targetingGO:1903533290.015
establishment or maintenance of cell polarityGO:00071631670.015
regulation of wnt signaling pathwayGO:0030111680.015
bmp signaling pathwayGO:0030509270.015
embryonic organ developmentGO:0048568500.015
determination of adult lifespanGO:00083401370.015
defense response to other organismGO:00985422250.015
cellular amino acid metabolic processGO:0006520610.015
tube morphogenesisGO:00352391910.015
intracellular protein transportGO:00068861040.015
ribonucleoprotein complex subunit organizationGO:0071826280.015
small gtpase mediated signal transductionGO:0007264880.015
dorsal ventral pattern formationGO:00099531330.015
organelle assemblyGO:00709251980.015
regulation of multicellular organismal developmentGO:20000264140.015
Fly
centrosome organizationGO:00512971630.015
protein localization to organelleGO:0033365820.015
response to woundingGO:0009611940.014
retinal ganglion cell axon guidanceGO:0031290120.014
negative regulation of apoptotic processGO:0043066630.014
chemosensory behaviorGO:00076351060.014
morphogenesis of a branching epitheliumGO:0061138450.014
sperm individualizationGO:0007291480.014
positive regulation of mapk cascadeGO:0043410630.014
positive regulation of phosphate metabolic processGO:00459371390.014
rho protein signal transductionGO:0007266140.014
mesenchymal cell developmentGO:001403110.014
peripheral nervous system developmentGO:0007422520.014
renal tubule developmentGO:0061326640.014
muscle structure developmentGO:00610612240.014
nuclear importGO:0051170510.014
regulation of cellular amine metabolic processGO:003323830.014
morphogenesis of follicular epitheliumGO:0016333360.014
cellular lipid metabolic processGO:0044255830.014
peptidyl amino acid modificationGO:00181931050.013
response to nutrient levelsGO:00316671140.013
positive regulation of apoptotic signaling pathwayGO:200123540.013
antimicrobial humoral responseGO:0019730990.013
multicellular organismal agingGO:00102591400.013
regulation of neuron apoptotic processGO:0043523160.013
peptidyl tyrosine modificationGO:0018212240.013
mrna processingGO:00063971040.013
negative regulation of defense responseGO:0031348350.013
actin cytoskeleton organizationGO:00300362060.013
response to radiationGO:00093141550.013
Fly
telencephalon developmentGO:002153720.013
cellularizationGO:0007349900.013
nuclear transcribed mrna catabolic processGO:0000956240.013
response to nitrogen compoundGO:1901698900.013
dorsal ventral axis specificationGO:0009950660.013
protein import into nucleusGO:0006606510.013
digestive tract developmentGO:00485651490.013
meiotic cell cycle processGO:19030461320.013
positive regulation of developmental growthGO:0048639620.013
salivary gland morphogenesisGO:00074351450.012
eggshell formationGO:00307031050.012
positive regulation of protein complex assemblyGO:0031334220.012
regulation of nucleocytoplasmic transportGO:0046822350.012
regulation of cellular ketone metabolic processGO:001056530.012
centrosome cycleGO:00070981370.012
positive regulation of synapse assemblyGO:0051965290.012
dorsal closureGO:0007391790.012
regulation of catalytic activityGO:00507901850.012
neuromuscular junction developmentGO:00075281490.012
epithelial cell differentiationGO:00308553220.012
synaptic growth at neuromuscular junctionGO:00511241190.012
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101180.012
regulation of cell cycleGO:00517262910.012
regulation of notch signaling pathwayGO:00085931000.012
mrna splicing via spliceosomeGO:0000398730.012
pattern recognition receptor signaling pathwayGO:000222120.012
positive regulation of endopeptidase activityGO:0010950260.012
regulation of kinase activityGO:0043549530.012
single organism cell adhesionGO:0098602470.012
multi multicellular organism processGO:00447061230.012
regulation of transferase activityGO:0051338580.012
matingGO:00076181200.012
spermatid developmentGO:0007286980.012
organic cyclic compound catabolic processGO:19013611680.012
ribonucleoprotein complex assemblyGO:0022618230.011
cellular response to growth factor stimulusGO:0071363300.011
regulation of cell sizeGO:0008361630.011
Fly
axon regenerationGO:003110380.011
cellular macromolecular complex assemblyGO:00346221530.011
establishment of localization in cellGO:00516494020.011
regulation of hemocyte proliferationGO:0035206370.011
positive regulation of i kappab kinase nf kappab signalingGO:004312310.011
regulation of mitosisGO:0007088560.011
nucleobase containing compound catabolic processGO:00346551650.011
ribonucleoprotein complex biogenesisGO:0022613310.011
hormone metabolic processGO:0042445330.011
sodium ion transportGO:0006814220.011
regulation of cellular amino acid metabolic processGO:000652100.011
positive regulation of organelle organizationGO:0010638650.011
negative regulation of phosphorylationGO:0042326350.011
regulation of tube size open tracheal systemGO:0035151430.010
response to fungusGO:0009620500.010
wnt signaling pathwayGO:0016055980.010
positive regulation of biosynthetic processGO:00098913160.010
adult behaviorGO:00305341370.010
Fly
modification dependent protein catabolic processGO:0019941780.010
regulation of erk1 and erk2 cascadeGO:0070372390.010
germline ring canal formationGO:0030725130.010
axon target recognitionGO:0007412160.010
carbohydrate derivative metabolic processGO:19011352170.010
protein localization to nucleusGO:0034504550.010
regulation of protein localization to nucleusGO:1900180290.010

Sema-1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.033
cancerDOID:16200.011
organ system cancerDOID:005068600.011
disease of cellular proliferationDOID:1456600.011