Drosophila melanogaster

69 known processes

tlk (Dmel_CG34412)

Tousled-like kinase

(Aliases: BcDNA:GH07910,EP1413,anon-WO03040301.114,anon-WO03040301.116,CG34412,Tlk,Dmel_CG32782,Dmel_CG32781,CG32782,CG32781,CG33219,l(1)G0054,CG12462,TLK,CG2829,Dmel\CG34412,dtlk,EP(X)1413)

tlk biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
deathGO:00162652840.654
imaginal disc derived wing morphogenesisGO:00074763370.570
positive regulation of gene expressionGO:00106282900.435
negative regulation of cellular metabolic processGO:00313243820.381
Human
imaginal disc derived appendage morphogenesisGO:00351143950.373
glial cell differentiationGO:0010001350.346
cell deathGO:00082192790.313
centrosome cycleGO:00070981370.301
imaginal disc derived appendage developmentGO:00487373990.300
immune system processGO:00023763470.259
gliogenesisGO:0042063800.254
developmental maturationGO:00217001720.239
tissue deathGO:00162711020.225
centrosome duplicationGO:00512981210.216
regulation of cell developmentGO:00602842150.213
wing disc morphogenesisGO:00074723440.180
programmed cell deathGO:00125012570.169
positive regulation of macromolecule metabolic processGO:00106044050.169
Worm
head developmentGO:00603221350.155
intracellular transportGO:00469072280.154
Human
salivary gland developmentGO:00074311620.153
cell cycle comprising mitosis without cytokinesisGO:0033301250.150
appendage developmentGO:00487364010.141
regionalizationGO:00030024160.128
regulation of programmed cell deathGO:00430671520.126
dendrite developmentGO:00163582040.117
regulation of cell cycleGO:00517262910.117
post embryonic appendage morphogenesisGO:00351203850.114
regulation of multi organism processGO:00439001310.114
cell fate determinationGO:0001709910.114
meiotic cell cycle processGO:19030461320.112
eye developmentGO:00016543230.111
anterior posterior axis specificationGO:00099481090.109
cellular protein modification processGO:00064644380.105
chemosensory behaviorGO:00076351060.101
cellular response to dna damage stimulusGO:00069742230.100
Human
positive regulation of macromolecule biosynthetic processGO:00105572830.098
developmental programmed cell deathGO:00106231380.098
establishment of localization in cellGO:00516494020.097
Human
positive regulation of cell developmentGO:0010720610.095
negative regulation of transcription dna templatedGO:00458922370.094
organelle fissionGO:00482853400.093
protein localizationGO:00081042840.093
Human
gland developmentGO:00487321910.093
regulation of cell deathGO:00109411730.092
secretionGO:00469031090.092
negative regulation of gene expression epigeneticGO:0045814770.092
gland morphogenesisGO:00226121450.091
stem cell differentiationGO:00488631170.090
positive regulation of rna metabolic processGO:00512542710.088
macromolecule catabolic processGO:00090571610.088
Human
salivary gland cell autophagic cell deathGO:0035071830.086
positive regulation of nucleic acid templated transcriptionGO:19035082660.083
single organism intracellular transportGO:19025822070.082
dendrite morphogenesisGO:00488131990.081
dna metabolic processGO:00062592270.081
negative regulation of nervous system developmentGO:0051961920.081
microtubule organizing center organizationGO:00310231680.080
cell proliferationGO:00082832990.077
defense responseGO:00069523000.077
cell cycle checkpointGO:0000075950.077
cell motilityGO:00488702510.074
organic substance transportGO:00717022570.071
Human
glial cell developmentGO:0021782270.070
negative regulation of neurogenesisGO:0050768530.070
negative regulation of developmental processGO:00510932010.067
regulation of proteolysisGO:0030162870.067
Human
chromatin organizationGO:00063252070.066
mitotic spindle organizationGO:00070522200.066
central nervous system developmentGO:00074172010.066
phosphorylationGO:00163102940.065
digestive tract morphogenesisGO:00485461270.065
apoptotic processGO:00069151590.064
regulation of developmental growthGO:00486381740.063
Worm
segmentationGO:00352822070.063
protein modification processGO:00362114380.060
centrosome organizationGO:00512971630.059
positive regulation of nucleobase containing compound metabolic processGO:00459353320.058
negative regulation of nucleobase containing compound metabolic processGO:00459342610.058
positive regulation of proteolysisGO:0045862520.057
transcription from rna polymerase ii promoterGO:00063663680.057
Worm
tube developmentGO:00352952440.056
regulation of cell differentiationGO:00455953020.055
regulation of chromosome organizationGO:0033044640.055
Human
negative regulation of gene expressionGO:00106293870.054
Human
regulation of cell cycle phase transitionGO:19019871300.054
regulation of protein metabolic processGO:00512462560.053
Human Worm
regulation of multicellular organismal developmentGO:20000264140.053
negative regulation of multicellular organismal processGO:00512411420.052
spindle elongationGO:0051231830.052
ecdysone mediated induction of salivary gland cell autophagic cell deathGO:0035072120.051
developmental growthGO:00485892800.050
Worm
embryonic morphogenesisGO:00485982060.050
protein transportGO:00150311550.050
Human
salivary gland morphogenesisGO:00074351450.050
regulation of molecular functionGO:00650092170.049
Worm
regulation of anatomical structure morphogenesisGO:00226032420.049
cell divisionGO:00513012480.049
negative regulation of nucleic acid templated transcriptionGO:19035072400.049
regulation of mitotic cell cycleGO:00073461900.048
vesicle mediated transportGO:00161923810.048
negative regulation of biosynthetic processGO:00098902770.047
positive regulation of rna biosynthetic processGO:19026802660.047
positive regulation of biosynthetic processGO:00098913160.047
blastoderm segmentationGO:00073501590.047
regulation of neuron differentiationGO:00456641030.047
nuclear divisionGO:00002803320.047
meiotic cell cycleGO:00513211710.047
gene silencingGO:00164581380.047
spindle organizationGO:00070512530.047
histolysisGO:00075591020.046
salivary gland histolysisGO:0035070880.046
cellular component disassemblyGO:0022411460.046
compound eye photoreceptor fate commitmentGO:0001752360.044
mitotic nuclear divisionGO:00070672130.043
posttranscriptional gene silencing by rnaGO:0035194450.043
brain developmentGO:00074201200.043
exocrine system developmentGO:00352721620.042
negative regulation of nitrogen compound metabolic processGO:00511722650.042
regulation of gene expression epigeneticGO:00400291280.041
cellular macromolecular complex assemblyGO:00346221530.041
embryonic development via the syncytial blastodermGO:00017001480.041
camera type eye developmentGO:004301040.040
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.040
cellular response to chemical stimulusGO:00708871990.039
dna conformation changeGO:00711031050.039
negative regulation of cell proliferationGO:0008285690.038
stem cell fate commitmentGO:0048865250.038
morphogenesis of an epitheliumGO:00020092760.038
negative regulation of rna metabolic processGO:00512532510.038
digestive tract developmentGO:00485651490.038
establishment of protein localization to organelleGO:0072594620.038
regulation of cell proliferationGO:00421271630.037
embryonic pattern specificationGO:00098801740.037
regulation of immune system processGO:00026821760.036
translationGO:0006412690.036
dna replicationGO:0006260480.036
negative regulation of protein metabolic processGO:0051248850.036
Human
organelle localizationGO:00516401480.036
phagocytosisGO:00069092150.036
eye morphogenesisGO:00485922600.036
homeostatic processGO:00425921990.035
forebrain developmentGO:003090020.035
biological adhesionGO:00226101380.035
negative regulation of cellular biosynthetic processGO:00313272770.035
response to oxygen containing compoundGO:19017002000.034
proteolysisGO:00065081920.034
Human
secretion by cellGO:00329401010.034
chromosome organizationGO:00512763600.033
localization of cellGO:00516742570.033
regulation of mrna processingGO:0050684710.033
tube morphogenesisGO:00352391910.033
dna packagingGO:0006323910.032
anterior posterior pattern specificationGO:00099521360.032
autophagic cell deathGO:0048102830.032
regulation of cellular protein metabolic processGO:00322682430.032
Human Worm
locomotory behaviorGO:00076261760.032
peptidyl amino acid modificationGO:00181931050.032
Human
regulation of cellular localizationGO:00603411360.031
sensory organ morphogenesisGO:00905962600.031
negative regulation of cell differentiationGO:00455961430.031
single organism behaviorGO:00447083910.030
compound eye morphogenesisGO:00017452490.030
regulation of cell cycle processGO:00105641810.029
positive regulation of transcription dna templatedGO:00458932660.029
cellular macromolecule localizationGO:00707272200.029
Human
smoothened signaling pathwayGO:0007224490.029
taxisGO:00423303040.029
regulation of cellular amine metabolic processGO:003323830.029
catabolic processGO:00090564090.029
Human
chromatin modificationGO:00165681470.028
respiratory system developmentGO:00605412130.028
muscle structure developmentGO:00610612240.028
posttranscriptional regulation of gene expressionGO:00106081450.027
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.027
positive regulation of mitotic cell cycle phase transitionGO:1901992200.027
protein acylationGO:0043543420.026
circulatory system developmentGO:0072359820.026
protein complex biogenesisGO:00702712010.026
neuroblast fate commitmentGO:0014017190.026
response to biotic stimulusGO:00096072940.026
tissue morphogenesisGO:00487292970.025
negative regulation of cell cycle phase transitionGO:19019881030.025
positive regulation of cell proliferationGO:0008284470.025
positive regulation of cellular amine metabolic processGO:003324000.025
cell maturationGO:00484691440.025
positive regulation of mitotic cell cycleGO:0045931340.025
protein importGO:0017038550.025
positive regulation of developmental processGO:00510941430.024
Worm
regulation of transcription from rna polymerase ii promoterGO:00063573780.024
Worm
induction of programmed cell deathGO:0012502120.024
positive regulation of cell differentiationGO:0045597640.024
regulation of localizationGO:00328792750.023
sister chromatid segregationGO:0000819920.023
olfactory behaviorGO:0042048970.023
regulation of anatomical structure sizeGO:00900661630.023
cell adhesionGO:00071551360.023
regulation of response to external stimulusGO:00321011150.023
compound eye developmentGO:00487493070.023
protein targetingGO:0006605640.023
nuclear transportGO:0051169720.023
negative regulation of cellular protein metabolic processGO:0032269850.023
Human
photoreceptor cell developmentGO:0042461960.023
mitotic cell cycle phase transitionGO:00447721380.023
growthGO:00400073590.023
Worm
endocytosisGO:00068973100.022
response to ecdysoneGO:0035075340.022
telencephalon developmentGO:002153720.022
response to ketoneGO:1901654340.022
imaginal disc derived wing vein morphogenesisGO:0008586440.022
stem cell maintenanceGO:0019827670.021
regulation of nervous system developmentGO:00519602480.021
cognitionGO:00508901410.021
mrna metabolic processGO:00160711240.021
regulation of mitotic cell cycle phase transitionGO:19019901300.021
axonogenesisGO:00074092900.021
modification dependent protein catabolic processGO:0019941780.021
Human
regulation of growthGO:00400082330.021
Worm
regulation of endopeptidase activityGO:0052548360.021
eye photoreceptor cell developmentGO:0042462810.021
induction of programmed cell death by ecdysoneGO:0035078120.021
negative regulation of cell deathGO:0060548810.020
regulation of apoptotic processGO:00429811300.020
protein import into nucleusGO:0006606510.020
protein localization to nucleusGO:0034504550.020
embryo development ending in birth or egg hatchingGO:00097921520.020
Worm
meiotic nuclear divisionGO:00071261510.020
neuroblast proliferationGO:0007405740.020
regulation of gliogenesisGO:0014013110.020
negative regulation of developmental growthGO:0048640640.020
tripartite regional subdivisionGO:00073511030.020
regulation of translationGO:0006417560.020
microtubule based movementGO:0007018510.020
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.020
Human
response to abiotic stimulusGO:00096283410.019
Human
positive regulation of cellular biosynthetic processGO:00313283160.019
chemotaxisGO:00069352490.019
cellular catabolic processGO:00442483720.019
Human
cellular protein localizationGO:00346131600.019
Human
retina development in camera type eyeGO:006004140.019
negative regulation of phosphate metabolic processGO:0045936450.019
positive regulation of protein metabolic processGO:00512471280.019
Worm
response to other organismGO:00517072930.019
photoreceptor cell fate commitmentGO:0046552410.019
positive regulation of cell deathGO:0010942690.018
circadian behaviorGO:0048512760.018
dorsal ventral pattern formationGO:00099531330.018
compound eye photoreceptor cell differentiationGO:00017511400.018
positive regulation of cell cycleGO:0045787430.017
regulation of response to stressGO:00801342000.017
defense response to other organismGO:00985422250.017
establishment of organelle localizationGO:00516561220.017
positive regulation of molecular functionGO:00440931360.017
Worm
negative regulation of cell communicationGO:00106482230.017
intracellular protein transportGO:00068861040.017
Human
negative regulation of mitotic cell cycleGO:00459301090.017
chromatin silencingGO:0006342760.017
response to radiationGO:00093141550.017
Human
cellular amine metabolic processGO:0044106120.017
hindgut morphogenesisGO:0007442580.017
chromatin assemblyGO:0031497480.017
negative regulation of programmed cell deathGO:0043069720.016
reproductive behaviorGO:00190981220.016
nucleocytoplasmic transportGO:0006913720.016
protein targeting to nucleusGO:0044744510.016
nuclear importGO:0051170510.016
histone ubiquitinationGO:001657440.016
regulation of mrna metabolic processGO:1903311720.016
mitotic sister chromatid segregationGO:0000070870.016
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281250.015
wnt signaling pathwayGO:0016055980.015
enzyme linked receptor protein signaling pathwayGO:00071671790.015
amine metabolic processGO:0009308120.015
mesenchymal cell differentiationGO:004876210.015
epithelial cell differentiationGO:00308553220.015
spinal cord developmentGO:002151010.015
adult behaviorGO:00305341370.015
protein phosphorylationGO:00064681690.015
regulation of cellular ketone metabolic processGO:001056530.015
dna endoreduplicationGO:0042023220.015
response to bacteriumGO:00096171980.014
cell cycle phase transitionGO:00447701400.014
negative regulation of response to stimulusGO:00485852580.014
compound eye photoreceptor developmentGO:0042051780.014
positive regulation of cellular amino acid metabolic processGO:004576400.014
axis specificationGO:00097981670.014
negative regulation of transcription regulatory region dna bindingGO:200067830.014
chromosome segregationGO:00070591570.014
appendage morphogenesisGO:00351073970.014
regulation of neuroblast proliferationGO:1902692340.014
cell cycle g1 s phase transitionGO:0044843310.014
establishment or maintenance of cell polarityGO:00071631670.014
protein localization to organelleGO:0033365820.014
actin filament based processGO:00300292200.014
metaphase plate congressionGO:0051310190.014
neuron projection guidanceGO:00974852410.014
cell migrationGO:00164772380.013
cranial nerve developmentGO:002154510.013
positive regulation of apoptotic processGO:0043065470.013
regulation of cell divisionGO:0051302720.013
regulation of neurogenesisGO:00507671580.013
gastrulation with mouth forming firstGO:0001703360.013
regulation of embryonic developmentGO:0045995680.013
asymmetric cell divisionGO:0008356370.013
response to nutrient levelsGO:00316671140.013
regulation of glial cell differentiationGO:004568510.013
muscle organ developmentGO:00075171270.013
positive regulation of catabolic processGO:00098961050.013
organic substance catabolic processGO:19015753080.013
Human
macromolecular complex assemblyGO:00650032560.013
negative regulation of cell developmentGO:0010721620.013
establishment of chromosome localizationGO:0051303200.013
spermatogenesisGO:00072832000.012
regulation of phosphate metabolic processGO:00192202100.012
Worm
positive regulation of response to stimulusGO:00485843230.012
peripheral nervous system developmentGO:0007422520.012
negative regulation of mitotic cell cycle phase transitionGO:19019911030.012
agingGO:00075681430.012
neuroblast divisionGO:0055057350.012
organonitrogen compound metabolic processGO:19015643180.012
positive regulation of cell migrationGO:003033520.012
negative regulation of macromolecule biosynthetic processGO:00105582700.012
regulation of gene silencingGO:0060968630.012
rna processingGO:00063961470.012
ras protein signal transductionGO:0007265880.012
single organism nuclear importGO:1902593510.012
response to organic substanceGO:00100332840.012
response to sterolGO:0036314340.012
neuron maturationGO:0042551310.012
regulation of transportGO:00510491810.012
meiosis iGO:0007127590.011
actomyosin structure organizationGO:0031032560.011
positive regulation of bindingGO:005109940.011
digestive system developmentGO:00551231490.011
signal releaseGO:0023061490.011
cytoplasmic transportGO:00164821300.011
ubiquitin dependent protein catabolic processGO:0006511780.011
Human
eye photoreceptor cell differentiationGO:00017541450.011
regulation of synapse assemblyGO:0051963940.011
cardiovascular system developmentGO:0072358820.011
negative regulation of signal transductionGO:00099682060.011
regulation of protein localizationGO:0032880760.010
neural retina developmentGO:000340740.010
regulation of glial cell proliferationGO:0060251110.010
positive regulation of transportGO:0051050920.010
intracellular steroid hormone receptor signaling pathwayGO:0030518120.010
chromatin assembly or disassemblyGO:0006333520.010
Human
stem cell developmentGO:0048864790.010
mesenchymal cell developmentGO:001403110.010
positive regulation of nitrogen compound metabolic processGO:00511733540.010
establishment of nucleus localizationGO:0040023260.010
larval developmentGO:00021641040.010
ovarian follicle cell developmentGO:00307072480.010
dna integrity checkpointGO:0031570810.010
proteasomal protein catabolic processGO:0010498590.010
Human
regulation of hydrolase activityGO:0051336970.010

tlk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.013