IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

CG8661 (Dmel_CG8661)

CG8661 gene product from transcript CG8661-RA

(Aliases: Dmel\CG8661,BcDNA:LP01183)

Entrez: 32720
FLYBASE: FBgn0030837
UniProtKB: Q9VX57

Process Predictions
Disease Predictions

CG8661 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability
immune response	GO:0006955	246	0.081
response to abiotic stimulus	GO:0009628	341	0.079
defense response to other organism	GO:0098542	225	0.066
response to biotic stimulus	GO:0009607	294	0.062
immune system process	GO:0002376	347	0.061
defense response	GO:0006952	300	0.061
innate immune response	GO:0045087	144	0.059
positive regulation of signaling	GO:0023056	243	0.058
defense response to bacterium	GO:0042742	178	0.052
homeostatic process	GO:0042592	199	0.048
positive regulation of signal transduction	GO:0009967	223	0.048
positive regulation of response to stimulus	GO:0048584	323	0.045
response to temperature stimulus	GO:0009266	106	0.043
positive regulation of cell communication	GO:0010647	250	0.043
cellular catabolic process	GO:0044248	372	0.039
macromolecular complex assembly	GO:0065003	256	0.039
endocytosis	GO:0006897	310	0.038
vesicle mediated transport	GO:0016192	381	0.037
defense response to gram positive bacterium	GO:0050830	41	0.036
appendage morphogenesis	GO:0035107	397	0.036
organonitrogen compound metabolic process	GO:1901564	318	0.036
imaginal disc derived appendage development	GO:0048737	399	0.034
response to other organism	GO:0051707	293	0.034
negative regulation of response to stimulus	GO:0048585	258	0.030
small molecule metabolic process	GO:0044281	305	0.030
catabolic process	GO:0009056	409	0.028
appendage development	GO:0048736	401	0.028
protein modification process	GO:0036211	438	0.027
positive regulation of sequestering of triglyceride	GO:0010890	1	0.026
response to bacterium	GO:0009617	198	0.026
regulation of multi organism process	GO:0043900	131	0.026
developmental programmed cell death	GO:0010623	138	0.026
chemical homeostasis	GO:0048878	92	0.026
imaginal disc derived wing morphogenesis	GO:0007476	337	0.025
response to external biotic stimulus	GO:0043207	293	0.025
wing disc morphogenesis	GO:0007472	344	0.025
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.024
response to cold	GO:0009409	13	0.024
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.024
gland development	GO:0048732	191	0.023
post embryonic appendage morphogenesis	GO:0035120	385	0.023
cellular protein modification process	GO:0006464	438	0.023
body morphogenesis	GO:0010171	2	0.023
oxoacid metabolic process	GO:0043436	103	0.022
regulation of localization	GO:0032879	275	0.022
phagocytosis	GO:0006909	215	0.022
epithelial cell differentiation	GO:0030855	322	0.022
activation of innate immune response	GO:0002218	4	0.022
proteolysis	GO:0006508	192	0.021
neurological system process	GO:0050877	358	0.021
regulation of response to biotic stimulus	GO:0002831	63	0.021
defense response to gram negative bacterium	GO:0050829	94	0.021
organic substance catabolic process	GO:1901575	308	0.021
ethanolamine containing compound metabolic process	GO:0042439	4	0.020
ovarian follicle cell development	GO:0030707	248	0.020
defense response to fungus	GO:0050832	48	0.020
response to radiation	GO:0009314	155	0.020
positive regulation of biosynthetic process	GO:0009891	316	0.020
negative regulation of gene expression	GO:0010629	387	0.020
epithelial cell development	GO:0002064	274	0.019
carboxylic acid metabolic process	GO:0019752	92	0.019
organic substance transport	GO:0071702	257	0.019
eggshell formation	GO:0030703	105	0.019
regulation of response to external stimulus	GO:0032101	115	0.019
negative regulation of signal transduction	GO:0009968	206	0.019
camera type eye development	GO:0043010	4	0.019
regulation of cell cycle	GO:0051726	291	0.019
gland morphogenesis	GO:0022612	145	0.019
immune response regulating signaling pathway	GO:0002764	2	0.019
cell proliferation	GO:0008283	299	0.019
chorion containing eggshell formation	GO:0007304	105	0.018
compound eye development	GO:0048749	307	0.018
negative regulation of cell communication	GO:0010648	223	0.018
forebrain development	GO:0030900	2	0.018
cholesterol homeostasis	GO:0042632	3	0.018
peptide metabolic process	GO:0006518	80	0.018
regulation of cellular amine metabolic process	GO:0033238	3	0.018
carbohydrate derivative metabolic process	GO:1901135	217	0.018
salivary gland morphogenesis	GO:0007435	145	0.018
exocrine system development	GO:0035272	162	0.018
toll signaling pathway	GO:0008063	25	0.018
protein complex assembly	GO:0006461	200	0.018
negative regulation of cellular metabolic process	GO:0031324	382	0.018
cellular amino acid metabolic process	GO:0006520	61	0.018
phosphorylation	GO:0016310	294	0.018
cellular amine metabolic process	GO:0044106	12	0.017
regulation of protein metabolic process	GO:0051246	256	0.017
sensory perception of mechanical stimulus	GO:0050954	72	0.017
response to oxygen containing compound	GO:1901700	200	0.017
compound eye morphogenesis	GO:0001745	249	0.017
regulation of cellular amino acid metabolic process	GO:0006521	0	0.017
amine metabolic process	GO:0009308	12	0.017
death	GO:0016265	284	0.017
organophosphate metabolic process	GO:0019637	195	0.016
cation transport	GO:0006812	110	0.016
columnar cuboidal epithelial cell development	GO:0002066	249	0.016
regulation of intracellular signal transduction	GO:1902531	236	0.016
regulation of cellular ketone metabolic process	GO:0010565	3	0.016
salivary gland development	GO:0007431	162	0.016
regulation of response to stress	GO:0080134	200	0.016
actin filament based process	GO:0030029	220	0.016
acylglycerol biosynthetic process	GO:0046463	2	0.015
organic acid metabolic process	GO:0006082	103	0.015
regulation of phosphorus metabolic process	GO:0051174	210	0.015
negative regulation of signaling	GO:0023057	219	0.015
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.015
programmed cell death	GO:0012501	257	0.015
single organism biosynthetic process	GO:0044711	206	0.015
protein maturation	GO:0051604	71	0.015
anion homeostasis	GO:0055081	3	0.015
developmental growth	GO:0048589	280	0.015
regulation of multicellular organismal development	GO:2000026	414	0.015
segmentation	GO:0035282	207	0.014
mitotic nuclear division	GO:0007067	213	0.014
response to fungus	GO:0009620	50	0.014
cell death	GO:0008219	279	0.014
regulation of molecular function	GO:0065009	217	0.014
single organism behavior	GO:0044708	391	0.014
autophagic cell death	GO:0048102	83	0.014
response to organic substance	GO:0010033	284	0.014
developmental maturation	GO:0021700	172	0.014
eye morphogenesis	GO:0048592	260	0.014
positive regulation of cell motility	GO:2000147	3	0.014
positive regulation of macromolecule metabolic process	GO:0010604	405	0.014
ion transport	GO:0006811	145	0.014
regulation of toll signaling pathway	GO:0008592	17	0.014
telencephalon development	GO:0021537	2	0.014
regulation of catalytic activity	GO:0050790	185	0.014
tissue death	GO:0016271	102	0.014
negative regulation of biosynthetic process	GO:0009890	277	0.013
transcription from rna polymerase ii promoter	GO:0006366	368	0.013
cell division	GO:0051301	248	0.013
salivary gland histolysis	GO:0035070	88	0.013
positive regulation of cell migration	GO:0030335	2	0.013
morphogenesis of an epithelium	GO:0002009	276	0.013
positive regulation of cellular biosynthetic process	GO:0031328	316	0.013
sensory perception	GO:0007600	196	0.013
regulation of innate immune response	GO:0045088	71	0.013
triglyceride biosynthetic process	GO:0019432	2	0.013
immune response activating signal transduction	GO:0002757	2	0.013
regulation of catabolic process	GO:0009894	170	0.013
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.013
regulation of cell differentiation	GO:0045595	302	0.013
regionalization	GO:0003002	416	0.013
regulation of cellular component biogenesis	GO:0044087	201	0.013
cellular nitrogen compound catabolic process	GO:0044270	165	0.013
regulation of cell death	GO:0010941	173	0.013
response to monosaccharide	GO:0034284	4	0.013
regulation of cellular protein metabolic process	GO:0032268	243	0.013
cellular component assembly involved in morphogenesis	GO:0010927	151	0.013
antimicrobial humoral response	GO:0019730	99	0.013
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.013
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.012
regulation of immune response	GO:0050776	118	0.012
sensory organ morphogenesis	GO:0090596	260	0.012
cellular macromolecule catabolic process	GO:0044265	136	0.012
regulation of transport	GO:0051049	181	0.012
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.012
adult behavior	GO:0030534	137	0.012
intracellular signal transduction	GO:0035556	300	0.012
hindbrain development	GO:0030902	2	0.012
positive regulation of multicellular organismal process	GO:0051240	143	0.012
embryonic pattern specification	GO:0009880	174	0.012
cellular response to chemical stimulus	GO:0070887	199	0.012
cellular ketone metabolic process	GO:0042180	24	0.012
aging	GO:0007568	143	0.012
cation homeostasis	GO:0055080	51	0.012
response to glucose	GO:0009749	2	0.012
positive regulation of cellular amine metabolic process	GO:0033240	0	0.012
response to organic cyclic compound	GO:0014070	89	0.012
eye development	GO:0001654	323	0.012
histolysis	GO:0007559	102	0.012
axon development	GO:0061564	297	0.012
macromolecule catabolic process	GO:0009057	161	0.012
response to hexose	GO:0009746	3	0.012
wnt signaling pathway	GO:0016055	98	0.012
regulation of phosphate metabolic process	GO:0019220	210	0.012
kidney development	GO:0001822	3	0.012
apoptotic process	GO:0006915	159	0.012
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.012
regulation of cellular catabolic process	GO:0031329	157	0.011
protein complex biogenesis	GO:0070271	201	0.011
small gtpase mediated signal transduction	GO:0007264	88	0.011
regulation of defense response	GO:0031347	102	0.011
establishment of localization in cell	GO:0051649	402	0.011
single organism catabolic process	GO:0044712	228	0.011
protein processing	GO:0016485	68	0.011
regulation of i kappab kinase nf kappab signaling	GO:0043122	2	0.011
carbohydrate derivative biosynthetic process	GO:1901137	85	0.011
organic cyclic compound catabolic process	GO:1901361	168	0.011
negative regulation of transcription dna templated	GO:0045892	237	0.011
gene silencing	GO:0016458	138	0.011
growth	GO:0040007	359	0.011
negative regulation of rna metabolic process	GO:0051253	251	0.011
regulation of programmed cell death	GO:0043067	152	0.011
cell cycle phase transition	GO:0044770	140	0.011
phosphatidic acid metabolic process	GO:0046473	1	0.011
aromatic compound catabolic process	GO:0019439	166	0.011
tissue morphogenesis	GO:0048729	297	0.011
organophosphate catabolic process	GO:0046434	112	0.011
camera type eye morphogenesis	GO:0048593	2	0.011
sulfur compound metabolic process	GO:0006790	59	0.011
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.011
organelle fission	GO:0048285	340	0.011
protein localization	GO:0008104	284	0.011
response to lipopolysaccharide	GO:0032496	4	0.011
response to extracellular stimulus	GO:0009991	116	0.011
cellular amide metabolic process	GO:0043603	80	0.011
nucleoside phosphate metabolic process	GO:0006753	162	0.011
positive regulation of phosphorus metabolic process	GO:0010562	139	0.011
negative regulation of developmental process	GO:0051093	201	0.011
negative regulation of cellular biosynthetic process	GO:0031327	277	0.011
multi organism behavior	GO:0051705	175	0.011
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.011
cell motility	GO:0048870	251	0.011
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.011
determination of adult lifespan	GO:0008340	137	0.010
positive regulation of gene expression	GO:0010628	290	0.010
protein phosphorylation	GO:0006468	169	0.010
sterol homeostasis	GO:0055092	4	0.010
response to light stimulus	GO:0009416	124	0.010
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.010
regulation of cell development	GO:0060284	215	0.010
organonitrogen compound catabolic process	GO:1901565	128	0.010
regulation of organelle organization	GO:0033043	196	0.010
cell maturation	GO:0048469	144	0.010
lateral inhibition	GO:0046331	206	0.010
positive regulation of immune response	GO:0050778	63	0.010
intracellular transport	GO:0046907	228	0.010
maintenance of location	GO:0051235	73	0.010
g protein coupled receptor signaling pathway	GO:0007186	136	0.010
rna processing	GO:0006396	147	0.010
positive regulation of intracellular signal transduction	GO:1902533	116	0.010
ras protein signal transduction	GO:0007265	88	0.010
positive regulation of rna metabolic process	GO:0051254	271	0.010
cellular response to organic substance	GO:0071310	132	0.010
multicellular organismal aging	GO:0010259	140	0.010
regulation of lipid transport	GO:0032368	3	0.010
positive regulation of rna biosynthetic process	GO:1902680	266	0.010
positive regulation of catalytic activity	GO:0043085	118	0.010

CG8661 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.045
disease of metabolism	DOID:0014667	0.029
urinary system disease	DOID:18	0.025
musculoskeletal system disease	DOID:17	0.024
kidney disease	DOID:557	0.021
renal tubular transport disease	DOID:447	0.021
type 2 diabetes mellitus	DOID:9352	0.019
carbohydrate metabolism disease	DOID:0050013	0.019
diabetes mellitus	DOID:9351	0.019
acquired metabolic disease	DOID:0060158	0.019
glucose metabolism disease	DOID:4194	0.019
hair disease	DOID:421	0.018
integumentary system disease	DOID:16	0.018
hypotrichosis	DOID:4535	0.018
nervous system disease	DOID:863	0.016
inherited metabolic disorder	DOID:655	0.013
connective tissue disease	DOID:65	0.013
sensory system disease	DOID:0050155	0.012
lipid metabolism disorder	DOID:3146	0.012
familial hyperlipidemia	DOID:1168	0.012
familial combined hyperlipidemia	DOID:13809	0.012
bone disease	DOID:0080001	0.012
cardiovascular system disease	DOID:1287	0.010

Loading network...

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network