Drosophila melanogaster

61 known processes

wupA (Dmel_CG7178)

wings up A

(Aliases: wup-A,WupA,Dmel\CG7178,HDP,TnI,hdp,DROTROPONI,Tn I,CG7178,TpnI,HLI,DmTpnI,HL08042,HL-I)

wupA biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
myofibril assemblyGO:0030239360.994
muscle cell developmentGO:0055001500.984
skeletal muscle adaptationGO:004350110.980
Mouse
sarcomere organizationGO:0045214260.969
cellular component assembly involved in morphogenesisGO:00109271510.955
muscle structure developmentGO:00610612240.942
striated muscle cell differentiationGO:0051146900.939
actin filament based processGO:00300292200.938
actin cytoskeleton organizationGO:00300362060.929
heart processGO:0003015370.923
organelle assemblyGO:00709251980.919
muscle cell differentiationGO:00426921030.902
striated muscle cell developmentGO:0055002500.855
striated muscle myosin thick filament assemblyGO:007168830.845
heart morphogenesisGO:0003007320.845
Mouse
actomyosin structure organizationGO:0031032560.816
mesoderm developmentGO:0007498780.794
protein complex biogenesisGO:00702712010.776
head developmentGO:00603221350.685
lipid storageGO:0019915380.674
actin filament based movementGO:0030048260.673
somatic muscle developmentGO:0007525660.656
heart contractionGO:0060047260.646
muscle organ morphogenesisGO:004864470.615
Mouse
circulatory system developmentGO:0072359820.613
circulatory system processGO:0003013370.596
actin filament cappingGO:005169320.588
heart developmentGO:0007507820.576
catabolic processGO:00090564090.563
muscle thin filament assemblyGO:007168950.551
cell motilityGO:00488702510.546
muscle organ developmentGO:00075171270.543
macromolecular complex assemblyGO:00650032560.534
muscle system processGO:0003012210.524
Mouse
striated muscle adaptationGO:001488810.520
Mouse
negative regulation of nucleobase containing compound metabolic processGO:00459342610.512
regulation of blood circulationGO:1903522210.509
regulation of organelle organizationGO:00330431960.491
skeletal myofibril assemblyGO:001486660.487
actin filament organizationGO:00070151260.463
protein catabolic processGO:00301631010.445
myotube cell developmentGO:001490430.435
regulation of protein complex disassemblyGO:0043244290.435
muscle contractionGO:0006936130.424
Mouse
central nervous system developmentGO:00074172010.410
purine ribonucleoside triphosphate catabolic processGO:00092071080.408
larval developmentGO:00021641040.407
reproductive behaviorGO:00190981220.399
muscle tissue morphogenesisGO:006041520.399
Mouse
purine ribonucleoside monophosphate metabolic processGO:0009167500.397
glycosyl compound metabolic processGO:19016571270.377
small molecule metabolic processGO:00442813050.376
purine containing compound metabolic processGO:00725211550.376
organic substance catabolic processGO:19015753080.351
regulation of actin filament depolymerizationGO:003083430.349
cellular macromolecular complex assemblyGO:00346221530.342
tube developmentGO:00352952440.335
protein complex assemblyGO:00064612000.334
nucleoside monophosphate metabolic processGO:0009123520.322
atp metabolic processGO:0046034490.309
transmembrane transportGO:00550851390.306
immune system processGO:00023763470.293
response to abiotic stimulusGO:00096283410.289
regulation of cell motilityGO:2000145230.278
regulation of heart contractionGO:0008016210.275
cardiovascular system developmentGO:0072358820.269
negative regulation of nitrogen compound metabolic processGO:00511722650.268
locomotory behaviorGO:00076261760.266
cellular response to reactive oxygen speciesGO:0034614140.258
multicellular organismal reproductive behaviorGO:00330571100.256
cell divisionGO:00513012480.252
nucleoside monophosphate catabolic processGO:0009125390.252
regulation of phosphate metabolic processGO:00192202100.251
phosphorylationGO:00163102940.249
anatomical structure homeostasisGO:0060249970.248
purine nucleoside metabolic processGO:00422781270.243
regulation of localizationGO:00328792750.234
vesicle mediated transportGO:00161923810.230
ribonucleoside triphosphate catabolic processGO:00092031080.230
actin mediated cell contractionGO:0070252210.230
maintenance of locationGO:0051235730.229
purine ribonucleotide catabolic processGO:00091541090.229
nucleotide catabolic processGO:00091661090.228
multi organism reproductive behaviorGO:00447051210.218
purine nucleotide catabolic processGO:00061951090.218
adult somatic muscle developmentGO:0007527140.218
regulation of cellular component biogenesisGO:00440872010.217
nucleobase containing compound catabolic processGO:00346551650.215
ribonucleoside metabolic processGO:00091191270.215
ribonucleoside monophosphate catabolic processGO:0009158390.213
ribonucleoside triphosphate metabolic processGO:00091991190.213
purine ribonucleotide metabolic processGO:00091501450.212
ribonucleoside monophosphate metabolic processGO:0009161510.210
cellular protein complex assemblyGO:0043623710.208
purine nucleoside catabolic processGO:00061521120.208
ribose phosphate metabolic processGO:00196931450.208
positive regulation of cellular component organizationGO:00511301560.205
striated muscle contractionGO:000694150.204
Mouse
intracellular signal transductionGO:00355563000.200
cell recognitionGO:00080371020.199
multi multicellular organism processGO:00447061230.196
organelle fissionGO:00482853400.196
purine nucleoside triphosphate catabolic processGO:00091461080.193
skeletal muscle myosin thick filament assemblyGO:003024130.191
regulation of purine nucleotide catabolic processGO:0033121480.189
negative regulation of actin filament depolymerizationGO:003083520.188
positive regulation of atp catabolic processGO:190329130.188
purine nucleoside monophosphate catabolic processGO:0009128380.186
cellular protein modification processGO:00064644380.184
purine ribonucleoside triphosphate metabolic processGO:00092051190.182
organophosphate metabolic processGO:00196371950.180
purine containing compound catabolic processGO:00725231120.179
purine ribonucleoside metabolic processGO:00461281270.179
response to inorganic substanceGO:0010035440.177
localization of cellGO:00516742570.171
macromolecule catabolic processGO:00090571610.166
regulation of phosphorus metabolic processGO:00511742100.165
nucleoside triphosphate catabolic processGO:00091431080.164
regulation of catalytic activityGO:00507901850.164
cytokinesisGO:0000910900.156
single organism behaviorGO:00447083910.154
positive regulation of catalytic activityGO:00430851180.154
nucleoside phosphate metabolic processGO:00067531620.154
nucleoside metabolic processGO:00091161270.153
cellular catabolic processGO:00442483720.151
body morphogenesisGO:001017120.149
protein modification processGO:00362114380.149
negative regulation of actin filament polymerizationGO:003083770.147
positive regulation of molecular functionGO:00440931360.146
purine ribonucleoside catabolic processGO:00461301120.145
embryo development ending in birth or egg hatchingGO:00097921520.143
Worm
regulation of locomotionGO:0040012420.143
positive regulation of nucleotide metabolic processGO:0045981550.141
ovipositionGO:0018991190.140
metal ion homeostasisGO:0055065440.139
Mouse
axonal fasciculationGO:0007413120.139
regulation of cellular catabolic processGO:00313291570.136
organic cyclic compound catabolic processGO:19013611680.136
carbohydrate derivative metabolic processGO:19011352170.134
carbohydrate derivative catabolic processGO:19011361180.132
regulation of transportGO:00510491810.131
regulation of catabolic processGO:00098941700.130
embryonic morphogenesisGO:00485982060.129
cardiac muscle tissue developmentGO:004873890.129
morphogenesis of an epitheliumGO:00020092760.128
striated muscle tissue developmentGO:0014706270.127
macromolecular complex disassemblyGO:0032984370.127
regulation of cellular component movementGO:0051270420.125
purine nucleoside triphosphate metabolic processGO:00091441190.122
adult behaviorGO:00305341370.122
myosin filament organizationGO:003103350.118
negative regulation of protein complex disassemblyGO:0043242230.116
stem cell differentiationGO:00488631170.115
kidney developmentGO:000182230.113
organonitrogen compound catabolic processGO:19015651280.109
positive regulation of nitrogen compound metabolic processGO:00511733540.105
regulation of nucleoside metabolic processGO:0009118500.105
regulation of system processGO:0044057360.104
Mouse
cell adhesionGO:00071551360.103
myosin filament assemblyGO:003103450.103
ribonucleoside catabolic processGO:00424541120.102
tissue migrationGO:00901301550.102
regulation of hydrolase activityGO:0051336970.100
stem cell proliferationGO:0072089880.099
actin filament bundle assemblyGO:0051017260.099
heterocycle catabolic processGO:00467001660.097
ribonucleotide catabolic processGO:00092611090.097
brain developmentGO:00074201200.095
nucleobase containing small molecule metabolic processGO:00550861740.095
regulation of heart rateGO:0002027110.093
purine ribonucleoside monophosphate catabolic processGO:0009169380.093
lipid localizationGO:0010876540.090
nucleotide metabolic processGO:00091171610.090
negative regulation of cytoskeleton organizationGO:0051494300.088
aromatic compound catabolic processGO:00194391660.087
negative regulation of cellular component organizationGO:00511291080.087
nucleoside catabolic processGO:00091641120.087
endocytosisGO:00068973100.084
cardiocyte differentiationGO:0035051290.081
regulation of cytoskeleton organizationGO:0051493890.081
columnar cuboidal epithelial cell developmentGO:00020662490.081
atp catabolic processGO:0006200380.079
establishment of localization in cellGO:00516494020.079
regulation of muscle contractionGO:000693750.078
Mouse
regulation of nucleotide metabolic processGO:0006140620.078
larval somatic muscle developmentGO:0007526190.077
positive regulation of nucleoside metabolic processGO:0045979470.076
nucleoside triphosphate metabolic processGO:00091411200.075
single organism catabolic processGO:00447122280.074
columnar cuboidal epithelial cell differentiationGO:00020652560.074
response to oxygen containing compoundGO:19017002000.073
organophosphate catabolic processGO:00464341120.073
positive regulation of phosphorus metabolic processGO:00105621390.072
axon developmentGO:00615642970.069
positive regulation of phosphate metabolic processGO:00459371390.068
purine nucleoside monophosphate metabolic processGO:0009126500.067
protein depolymerizationGO:0051261310.067
cellular protein complex disassemblyGO:0043624350.064
neuron recognitionGO:00080381010.063
ameboidal type cell migrationGO:00016671510.062
mating behaviorGO:00076171060.061
organonitrogen compound metabolic processGO:19015643180.061
regulation of cell migrationGO:0030334220.061
epithelium migrationGO:00901321480.061
regulation of molecular functionGO:00650092170.060
ribonucleotide metabolic processGO:00092591450.059
negative regulation of cellular metabolic processGO:00313243820.058
regulation of actin filament bundle assemblyGO:003223180.058
regulation of growthGO:00400082330.057
mitochondrion organizationGO:0007005650.056
cell proliferationGO:00082832990.056
apoptotic processGO:00069151590.055
biological adhesionGO:00226101380.054
ovulationGO:003072840.054
cellular response to chemical stimulusGO:00708871990.053
regulation of intracellular signal transductionGO:19025312360.053
regulation of nucleotide catabolic processGO:0030811480.052
growthGO:00400073590.052
protein localizationGO:00081042840.050
muscle fiber developmentGO:0048747120.050
regulation of purine nucleotide metabolic processGO:1900542620.049
regulation of actin filament lengthGO:0030832270.046
mitotic nuclear divisionGO:00070672130.045
regulation of cellular component sizeGO:0032535980.044
regulation of apoptotic processGO:00429811300.044
chromosome organizationGO:00512763600.042
positive regulation of hydrolase activityGO:0051345780.042
regulation of multicellular organismal developmentGO:20000264140.042
positive regulation of purine nucleotide metabolic processGO:1900544550.041
regulation of actin filament based processGO:0032970420.041
determination of adult lifespanGO:00083401370.041
centrosome organizationGO:00512971630.041
muscle tissue developmentGO:0060537300.041
negative regulation of gene expressionGO:00106293870.041
epithelial cell migration open tracheal systemGO:0007427320.040
microtubule organizing center organizationGO:00310231680.040
regulation of cellular localizationGO:00603411360.040
epithelial cell migrationGO:00106311480.040
regulation of reproductive processGO:2000241540.040
multi organism behaviorGO:00517051750.039
cellular nitrogen compound catabolic processGO:00442701650.039
negative regulation of response to stimulusGO:00485852580.038
positive regulation of nucleotide catabolic processGO:0030813460.037
positive regulation of nucleobase containing compound metabolic processGO:00459353320.037
negative regulation of organelle organizationGO:0010639560.036
deathGO:00162652840.035
regulation of cell deathGO:00109411730.035
immune system developmentGO:0002520570.035
response to hypoxiaGO:0001666530.035
hematopoietic or lymphoid organ developmentGO:0048534570.035
programmed cell deathGO:00125012570.034
neurotransmitter transportGO:0006836370.034
stem cell developmentGO:0048864790.034
male mating behaviorGO:0060179700.032
calcium ion homeostasisGO:0055074230.032
Mouse
negative regulation of signal transductionGO:00099682060.031
mitotic cytokinesisGO:0000281500.031
appendage developmentGO:00487364010.031
purine nucleotide metabolic processGO:00061631460.031
regulation of response to stressGO:00801342000.030
positive regulation of organelle organizationGO:0010638650.029
cellular chemical homeostasisGO:0055082400.029
Mouse
organic substance transportGO:00717022570.029
imaginal disc derived appendage developmentGO:00487373990.029
camera type eye developmentGO:004301040.028
matingGO:00076181200.028
tyrosine metabolic processGO:000657010.027
positive regulation of cell proliferationGO:0008284470.027
negative regulation of macromolecule biosynthetic processGO:00105582700.027
establishment of organelle localizationGO:00516561220.027
tissue morphogenesisGO:00487292970.027
Mouse
regulation of sarcomere organizationGO:006029720.027
adult locomotory behaviorGO:0008344760.026
synaptic vesicle localizationGO:0097479530.026
transcription from rna polymerase ii promoterGO:00063663680.025
negative regulation of phosphate metabolic processGO:0045936450.025
cell deathGO:00082192790.025
epithelial cell developmentGO:00020642740.025
regulation of vesicle mediated transportGO:0060627590.025
response to oxygen levelsGO:0070482590.024
muscle adaptationGO:004350010.024
Mouse
skeletal muscle fiber developmentGO:004874130.024
negative regulation of protein depolymerizationGO:1901880230.024
response to decreased oxygen levelsGO:0036293580.024
negative regulation of cell migrationGO:003033650.024
hemopoiesisGO:0030097460.024
regulation of protein depolymerizationGO:1901879270.023
renal system developmentGO:0072001720.023
positive regulation of catabolic processGO:00098961050.023
phagocytosisGO:00069092150.023
response to metal ionGO:0010038230.023
signal transduction by phosphorylationGO:00230141070.022
actin filament depolymerizationGO:003004250.022
imaginal disc derived appendage morphogenesisGO:00351143950.022
blood circulationGO:0008015260.022
actin filament bundle organizationGO:0061572280.021
negative regulation of catabolic processGO:0009895360.021
regulation of cell adhesionGO:0030155270.021
protein phosphorylationGO:00064681690.021
negative regulation of phosphorus metabolic processGO:0010563450.021
positive regulation of cellular component biogenesisGO:0044089800.020
regulation of actin cytoskeleton organizationGO:0032956420.020
protein targeting to nucleusGO:0044744510.020
respiratory system developmentGO:00605412130.020
negative regulation of molecular functionGO:0044092510.019
positive regulation of cellular catabolic processGO:0031331950.019
regulation of cell cycleGO:00517262910.019
cytoskeleton dependent cytokinesisGO:0061640810.019
receptor mediated endocytosisGO:0006898210.019
epidermis developmentGO:0008544650.019
glycosyl compound catabolic processGO:19016581120.019
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.018
response to oxidative stressGO:0006979860.018
reproductive structure developmentGO:0048608740.018
epithelial cell differentiationGO:00308553220.018
multicellular organismal agingGO:00102591400.018
mapk cascadeGO:00001651070.018
cellular response to organic substanceGO:00713101320.018
sex differentiationGO:0007548810.017
cellular response to oxygen containing compoundGO:1901701790.017
ovarian follicle cell developmentGO:00307072480.017
positive regulation of cytoskeleton organizationGO:0051495210.017
negative regulation of apoptotic processGO:0043066630.017
positive regulation of purine nucleotide catabolic processGO:0033123460.016
response to heatGO:0009408630.016
cardiac muscle cell differentiationGO:005500740.016
negative regulation of cellular catabolic processGO:0031330340.016
regulation of establishment of protein localizationGO:0070201610.016
regulation of dna templated transcription elongationGO:0032784170.016
skeletal muscle tissue developmentGO:0007519130.015
oocyte differentiationGO:00099941450.015
dopamine biosynthetic processGO:004241630.015
regulation of multi organism processGO:00439001310.015
hematopoietic progenitor cell differentiationGO:000224410.015
regulation of protein complex assemblyGO:0043254420.015
cellular amino acid metabolic processGO:0006520610.015
regulation of bindingGO:0051098160.015
cation homeostasisGO:0055080510.015
Mouse
posttranscriptional regulation of gene expressionGO:00106081450.015
agingGO:00075681430.015
myotube differentiationGO:0014902460.015
positive regulation of transportGO:0051050920.015
cation transportGO:00068121100.015
molting cycleGO:0042303560.015
regulation of protein modification processGO:00313991120.014
flightGO:0060361100.014
negative regulation of protein polymerizationGO:003227270.014
positive regulation of cellular protein metabolic processGO:00322701180.014
cellular component disassemblyGO:0022411460.014
regulation of cellular protein metabolic processGO:00322682430.014
response to light stimulusGO:00094161240.014
cellular macromolecule localizationGO:00707272200.013
regulation of i kappab kinase nf kappab signalingGO:004312220.013
actin polymerization or depolymerizationGO:0008154310.013
positive regulation of i kappab kinase nf kappab signalingGO:004312310.013
cellular metal ion homeostasisGO:0006875310.013
Mouse
positive regulation of biosynthetic processGO:00098913160.013
cellular divalent inorganic cation homeostasisGO:0072503230.013
Mouse
homeostatic processGO:00425921990.012
morphogenesis of a branching epitheliumGO:0061138450.012
regulation of immune system processGO:00026821760.012
tube morphogenesisGO:00352391910.012
synaptic transmissionGO:00072682880.012
organelle localizationGO:00516401480.012
response to reactive oxygen speciesGO:0000302240.012
germarium derived egg chamber formationGO:00072931010.012
nuclear divisionGO:00002803320.012
ion homeostasisGO:0050801550.011
Mouse
cell cycle arrestGO:000705040.011
forebrain developmentGO:003090020.011
mesenchymal cell developmentGO:001403110.011
regulation of endocytosisGO:0030100370.011
regulation of protein localizationGO:0032880760.011
response to calcium ionGO:005159210.011
developmental maturationGO:00217001720.011
protein polymerizationGO:0051258420.011
actin filament polymerizationGO:0030041270.011
positive regulation of stem cell differentiationGO:200073830.011
cellular response to abiotic stimulusGO:0071214580.010
cardiac cell developmentGO:005500630.010
regulation of secretion by cellGO:1903530390.010
positive regulation of cell adhesionGO:0045785100.010
secretion by cellGO:00329401010.010
nucleoside phosphate catabolic processGO:19012921100.010
regulation of actin polymerization or depolymerizationGO:0008064270.010
regulation of protein polymerizationGO:0032271280.010
organic acid metabolic processGO:00060821030.010
positive regulation of nucleic acid templated transcriptionGO:19035082660.010
regulation of cellular ketone metabolic processGO:001056530.010
wing disc morphogenesisGO:00074723440.010

wupA disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:1700.760
heart diseaseDOID:11400.760
cardiomyopathyDOID:005070000.760
myopathyDOID:42300.760
disease of anatomical entityDOID:700.760
intrinsic cardiomyopathyDOID:006003600.760
cardiovascular system diseaseDOID:128700.760
muscular diseaseDOID:008000000.760
muscle tissue diseaseDOID:6600.760
dilated cardiomyopathyDOID:1293000.760
nervous system diseaseDOID:86300.033
connective tissue diseaseDOID:6500.023
bone diseaseDOID:008000100.023
disease of cellular proliferationDOID:1456600.017
cancerDOID:16200.017