Drosophila melanogaster

185 known processes

Su(var)205 (Dmel_CG8409)

Suppressor of variegation 205

(Aliases: Suvar2-5,DmHP1,Su(var)2-05,HP1-VS,Su(Var)2-5,dHP-1a,hp1a,HP1,CG8409,E(var)29,Su(var)2-501,Su(var)[205],Su(var)29A,Suvar(2)5,dHP1,Su[Var]205,su(var)205,Hp1,Su(var),HP1alpha,Su-var(2)5,Dmel\CG8409,HP1a,Su[var]205,H3,HP-1,DmHP-1,Su(var)2-5,HP1A,SU(VAR)205,E(var)29A,hp1,Hp1a)

Su(var)205 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
chromatin assemblyGO:0031497480.998
negative regulation of rna metabolic processGO:00512532510.998
negative regulation of transcription dna templatedGO:00458922370.997
negative regulation of cellular metabolic processGO:00313243820.995
chromatin silencingGO:0006342760.995
negative regulation of gene expressionGO:00106293870.992
dna conformation changeGO:00711031050.990
chromatin remodelingGO:0006338720.985
chromosome organizationGO:00512763600.980
regulation of gene expression epigeneticGO:00400291280.976
negative regulation of gene expression epigeneticGO:0045814770.966
negative regulation of rna biosynthetic processGO:19026792400.964
negative regulation of cellular biosynthetic processGO:00313272770.936
dna packagingGO:0006323910.932
chromosome segregationGO:00070591570.926
cell proliferationGO:00082832990.919
negative regulation of macromolecule biosynthetic processGO:00105582700.912
dna modificationGO:000630450.908
dna metabolic processGO:00062592270.902
negative regulation of nucleobase containing compound metabolic processGO:00459342610.894
negative regulation of biosynthetic processGO:00098902770.893
negative regulation of nitrogen compound metabolic processGO:00511722650.881
gene silencingGO:00164581380.854
covalent chromatin modificationGO:00165691060.828
dna methylation or demethylationGO:004472840.789
positive regulation of nitrogen compound metabolic processGO:00511733540.774
meiotic cell cycleGO:00513211710.757
Fly
female meiotic divisionGO:0007143700.679
Fly
negative regulation of nucleic acid templated transcriptionGO:19035072400.663
histone lysine methylationGO:0034968320.650
chromatin organizationGO:00063252070.628
transcription from rna polymerase ii promoterGO:00063663680.602
Fly
negative regulation of chromosome organizationGO:2001251190.597
Fly
eye developmentGO:00016543230.592
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.584
histone h4 k20 methylationGO:003477040.578
chromatin modificationGO:00165681470.570
mitotic spindle organizationGO:00070522200.569
mitotic cell cycle phase transitionGO:00447721380.545
regulation of neurogenesisGO:00507671580.541
protein complex assemblyGO:00064612000.523
programmed cell deathGO:00125012570.502
spindle organizationGO:00070512530.495
organonitrogen compound metabolic processGO:19015643180.477
mitotic nuclear divisionGO:00070672130.466
meiotic cell cycle processGO:19030461320.459
macromolecular complex assemblyGO:00650032560.449
mitotic sister chromatid segregationGO:0000070870.447
organic substance catabolic processGO:19015753080.438
negative regulation of cellular protein metabolic processGO:0032269850.413
cell deathGO:00082192790.412
chromatin silencing at centromereGO:003070230.401
regulation of cell cycle phase transitionGO:19019871300.400
embryo development ending in birth or egg hatchingGO:00097921520.370
positive regulation of macromolecule metabolic processGO:00106044050.355
regulation of protein metabolic processGO:00512462560.346
regulation of cellular amine metabolic processGO:003323830.346
cellular protein modification processGO:00064644380.341
regulation of cell differentiationGO:00455953020.336
Worm
protein modification processGO:00362114380.332
regulation of cellular component biogenesisGO:00440872010.331
regulation of transcription from rna polymerase ii promoterGO:00063573780.329
Fly
eye photoreceptor cell differentiationGO:00017541450.328
proteolysisGO:00065081920.321
methylationGO:0032259470.309
positive regulation of protein metabolic processGO:00512471280.306
photoreceptor cell differentiationGO:00465301700.301
small molecule metabolic processGO:00442813050.284
gonad developmentGO:0008406500.269
Worm
positive regulation of histone h3 k9 methylationGO:005157430.266
negative regulation of cell cycleGO:00457861160.249
mitotic chromosome condensationGO:0007076220.241
mitotic sister chromatid separationGO:0051306300.240
chromosome condensationGO:0030261410.236
regulation of developmental growthGO:00486381740.235
Worm
regulation of proteolysisGO:0030162870.233
regulation of mitotic cell cycle phase transitionGO:19019901300.230
apoptotic processGO:00069151590.226
regulation of cellular protein metabolic processGO:00322682430.223
regulation of protein catabolic processGO:0042176550.220
regulation of heterochromatin assemblyGO:003144580.218
histone modificationGO:00165701060.215
cell cycle phase transitionGO:00447701400.214
regulation of mitotic cell cycleGO:00073461900.209
dna methylationGO:000630640.209
regulation of apoptotic processGO:00429811300.203
nuclear divisionGO:00002803320.195
Fly
body morphogenesisGO:001017120.191
eye morphogenesisGO:00485922600.181
sister chromatid segregationGO:0000819920.178
heterochromatin assemblyGO:0031507130.172
peptidyl amino acid modificationGO:00181931050.172
negative regulation of mitotic cell cycle phase transitionGO:19019911030.163
negative regulation of cell cycle phase transitionGO:19019881030.160
positive regulation of nucleobase containing compound metabolic processGO:00459353320.157
dna replicationGO:0006260480.156
regulation of cell developmentGO:00602842150.147
histone methylationGO:0016571400.140
positive regulation of cellular protein metabolic processGO:00322701180.135
nucleosome organizationGO:0034728590.133
stem cell divisionGO:0017145690.132
organophosphate metabolic processGO:00196371950.128
sensory organ morphogenesisGO:00905962600.122
organelle fissionGO:00482853400.121
Fly
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.121
negative regulation of cellular component organizationGO:00511291080.120
Fly
cellular catabolic processGO:00442483720.120
synaptonemal complex organizationGO:007019350.117
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.116
Fly
cell divisionGO:00513012480.113
regulation of cellular amino acid metabolic processGO:000652100.111
negative regulation of protein processingGO:0010955310.110
regulation of catalytic activityGO:00507901850.109
regulation of multi organism processGO:00439001310.108
negative regulation of proteolysisGO:0045861310.107
positive regulation of rna biosynthetic processGO:19026802660.106
Fly
dna hypermethylationGO:004402630.105
negative regulation of organelle organizationGO:0010639560.101
Fly
cellular macromolecule catabolic processGO:00442651360.101
positive regulation of phosphate metabolic processGO:00459371390.095
histone acetylationGO:0016573380.093
dendrite morphogenesisGO:00488131990.093
negative regulation of neuroblast proliferationGO:0007406270.092
regulation of cell divisionGO:0051302720.091
deathGO:00162652840.090
regulation of neuron differentiationGO:00456641030.090
peptidyl lysine dimethylationGO:001802730.089
chromosome separationGO:0051304420.088
negative regulation of neurogenesisGO:0050768530.087
positive regulation of response to stimulusGO:00485843230.087
regulation of protein modification processGO:00313991120.081
meiotic nuclear divisionGO:00071261510.080
Fly
regulation of meiosisGO:004002030.080
protein maturationGO:0051604710.079
macromolecule methylationGO:0043414450.078
histone exchangeGO:0043486210.075
protein complex biogenesisGO:00702712010.075
negative regulation of chromosome segregationGO:0051985140.073
dendrite developmentGO:00163582040.072
compound eye developmentGO:00487493070.072
regulation of molecular functionGO:00650092170.072
regulation of proteasomal protein catabolic processGO:0061136390.072
positive regulation of cell cycleGO:0045787430.071
positive regulation of cellular component organizationGO:00511301560.070
multi multicellular organism processGO:00447061230.067
epithelial cell differentiationGO:00308553220.067
macromolecule catabolic processGO:00090571610.065
protein dna complex subunit organizationGO:0071824860.064
regulation of cell cycleGO:00517262910.063
ovipositionGO:0018991190.063
negative regulation of cell divisionGO:0051782170.061
regulation of catabolic processGO:00098941700.060
compound eye morphogenesisGO:00017452490.060
reproductive behaviorGO:00190981220.059
neuron projection guidanceGO:00974852410.059
gland developmentGO:00487321910.057
larval developmentGO:00021641040.057
Worm
regulation of cell deathGO:00109411730.056
regulation of cell proliferationGO:00421271630.056
catabolic processGO:00090564090.056
negative regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032435160.055
regulation of nervous system developmentGO:00519602480.054
development of primary sexual characteristicsGO:0045137500.054
Worm
positive regulation of organelle organizationGO:0010638650.053
positive regulation of rna metabolic processGO:00512542710.053
Fly
multicellular organismal reproductive behaviorGO:00330571100.053
positive regulation of cellular component biogenesisGO:0044089800.053
regulation of cellular protein catabolic processGO:1903362440.052
positive regulation of signal transductionGO:00099672230.052
protein alkylationGO:0008213430.052
response to extracellular stimulusGO:00099911160.052
regulation of sister chromatid segregationGO:0033045280.052
negative regulation of meiotic cell cycleGO:005144720.051
vesicle mediated transportGO:00161923810.051
regulation of mitotic sister chromatid segregationGO:0033047280.050
peptidyl lysine modificationGO:0018205570.050
reproductive system developmentGO:0061458740.050
Worm
negative regulation of protein maturationGO:1903318310.050
negative regulation of mitotic cell cycleGO:00459301090.049
dna integrity checkpointGO:0031570810.047
positive regulation of catabolic processGO:00098961050.047
histone h3 k9 methylationGO:005156790.046
positive regulation of molecular functionGO:00440931360.046
regulation of cell cycle processGO:00105641810.046
negative regulation of nervous system developmentGO:0051961920.045
response to radiationGO:00093141550.045
dorsal vessel heart proper cell fate commitmentGO:003505320.044
negative regulation of multicellular organismal processGO:00512411420.043
Worm
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.042
regulation of chromosome organizationGO:0033044640.041
regulation of chromatin silencingGO:0031935360.041
Fly
regulation of phosphate metabolic processGO:00192202100.040
heterochromatin organizationGO:0070828250.040
regulation of nuclear divisionGO:0051783580.039
positive regulation of phosphorus metabolic processGO:00105621390.039
metaphase anaphase transition of cell cycleGO:0044784280.039
purine ribonucleotide metabolic processGO:00091501450.039
developmental growthGO:00485892800.038
Worm
multi organism reproductive behaviorGO:00447051210.038
regulation of cellular catabolic processGO:00313291570.037
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.037
modification dependent macromolecule catabolic processGO:0043632790.036
enzyme linked receptor protein signaling pathwayGO:00071671790.036
negative regulation of protein metabolic processGO:0051248850.036
aromatic compound catabolic processGO:00194391660.036
positive regulation of multicellular organismal processGO:00512401430.036
Worm
negative regulation of protein catabolic processGO:0042177170.036
multi organism behaviorGO:00517051750.034
glial cell migrationGO:0008347310.034
proteolysis involved in cellular protein catabolic processGO:0051603830.034
positive regulation of protein modification processGO:0031401580.034
oxoacid metabolic processGO:00434361030.033
regulation of transcription by chromatin organizationGO:003440130.033
phosphorylationGO:00163102940.033
protein catabolic processGO:00301631010.033
nucleus organizationGO:0006997450.032
single organism catabolic processGO:00447122280.032
posttranscriptional gene silencingGO:0016441460.032
growthGO:00400073590.031
Worm
negative regulation of cell cycle processGO:00109481090.031
negative regulation of cell proliferationGO:0008285690.030
camera type eye developmentGO:004301040.030
nucleoside monophosphate metabolic processGO:0009123520.029
rna processingGO:00063961470.029
rrna processingGO:000636430.029
gland morphogenesisGO:00226121450.029
positive regulation of catalytic activityGO:00430851180.028
peptidyl lysine acetylationGO:0018394390.028
nucleoside triphosphate metabolic processGO:00091411200.028
protein processingGO:0016485680.028
gliogenesisGO:0042063800.027
axon developmentGO:00615642970.027
cellular protein catabolic processGO:0044257830.027
compound eye photoreceptor cell differentiationGO:00017511400.026
nucleotide metabolic processGO:00091171610.026
positive regulation of dna metabolic processGO:0051054120.025
negative regulation of cellular catabolic processGO:0031330340.025
regulation of protein processingGO:0070613320.025
establishment or maintenance of polarity of larval imaginal disc epitheliumGO:001633630.025
negative regulation of cell differentiationGO:00455961430.024
positive regulation of cellular biosynthetic processGO:00313283160.024
Fly
positive regulation of cell communicationGO:00106472500.024
regulation of protein ubiquitinationGO:0031396220.024
positive regulation of protein import into nucleus translocationGO:003316020.024
ribose phosphate metabolic processGO:00196931450.023
carbohydrate derivative metabolic processGO:19011352170.023
nitric oxide metabolic processGO:004620910.023
ubiquitin dependent protein catabolic processGO:0006511780.023
establishment or maintenance of cell polarityGO:00071631670.023
regulation of homotypic cell cell adhesionGO:003411020.023
spindle assembly involved in mitosisGO:0090307500.022
regulation of gene silencingGO:0060968630.021
Fly
modification dependent protein catabolic processGO:0019941780.021
negative regulation of developmental processGO:00510932010.021
Worm
cellular response to nutrientGO:003167010.021
negative regulation of phosphate metabolic processGO:0045936450.021
regulation of meiotic cell cycleGO:005144590.021
regulation of hemocyte proliferationGO:0035206370.021
dendrite regenerationGO:003110420.021
regulation of intracellular signal transductionGO:19025312360.021
Worm
mitotic cell cycle checkpointGO:0007093880.020
positive regulation of cell cycle processGO:0090068280.020
genitalia developmentGO:0048806260.020
protein modification by small protein conjugation or removalGO:00706471060.020
regulation of hydrolase activityGO:0051336970.019
chromatin assembly or disassemblyGO:0006333520.019
signal transduction by phosphorylationGO:00230141070.019
regulation of cdc42 protein signal transductionGO:003248930.019
axonogenesisGO:00074092900.019
proteasomal protein catabolic processGO:0010498590.019
regulation of membrane potential in photoreceptor cellGO:001605740.019
oocyte morphogenesisGO:004860130.019
protein acetylationGO:0006473390.019
cellular response to chemical stimulusGO:00708871990.018
atp dependent chromatin remodelingGO:0043044220.018
heterocycle catabolic processGO:00467001660.018
regulation of striated muscle contractionGO:000694220.018
positive regulation of chromatin silencingGO:0031937160.018
Fly
positive regulation of cellular amine metabolic processGO:003324000.018
dna damage checkpointGO:0000077780.017
negative regulation of chromatin modificationGO:190330950.017
Fly
regulation of planar cell polarity pathway involved in axis elongationGO:200004020.017
neuroblast proliferationGO:0007405740.017
maternal determination of dorsal ventral axis ovarian follicular epithelium soma encodedGO:000807110.017
nucleoside metabolic processGO:00091161270.017
negative regulation of cell communicationGO:00106482230.017
Worm
reactive oxygen species biosynthetic processGO:190340900.016
negative regulation of intrinsic apoptotic signaling pathwayGO:200124310.016
intermediate filament cytoskeleton organizationGO:004510410.016
intermediate filament based processGO:004510310.016
telomere cappingGO:0016233110.016
Fly
regulation of phosphorylationGO:00423251470.016
cellular response to organic substanceGO:00713101320.016
response to organic substanceGO:00100332840.016
posttranscriptional regulation of gene expressionGO:00106081450.016
heterochromatin organization involved in chromatin silencingGO:007086890.016
regulation of organelle organizationGO:00330431960.016
cellular nitrogen compound catabolic processGO:00442701650.016
negative regulation of cell developmentGO:0010721620.016
regulation of multicellular organismal developmentGO:20000264140.016
Worm
posttranscriptional gene silencing by rnaGO:0035194450.015
positive regulation of mitotic cell cycleGO:0045931340.015
response to red or far red lightGO:000963920.015
immune system developmentGO:0002520570.015
positive regulation of chromatin silencing at telomereGO:003194020.015
Fly
cell cycle checkpointGO:0000075950.015
positive regulation of heterochromatin assemblyGO:003145350.015
regulation of protein modification by small protein conjugation or removalGO:1903320250.015
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clusteringGO:009711320.014
purine ribonucleoside catabolic processGO:00461301120.014
columnar cuboidal epithelial cell differentiationGO:00020652560.014
homeostatic processGO:00425921990.014
purine nucleoside metabolic processGO:00422781270.014
regulation of photoreceptor cell differentiationGO:0046532340.013
negative regulation of terminal cell fate specification open tracheal systemGO:003515520.013
regulation of protein maturationGO:1903317320.013
nucleobase containing small molecule metabolic processGO:00550861740.013
regulation of reactive oxygen species biosynthetic processGO:190342600.013
purine nucleoside catabolic processGO:00061521120.013
intracellular signal transductionGO:00355563000.013
Worm
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.013
convergent extensionGO:006002620.013
imaginal disc derived wing expansionGO:004852670.013
regulation of phosphorus metabolic processGO:00511742100.013
rna interferenceGO:0016246270.012
regulation of dna replicationGO:0006275130.012
retina development in camera type eyeGO:006004140.012
border follicle cell delaminationGO:003070930.012
pole cell formationGO:0007279190.012
regulation of cellular response to stressGO:0080135890.012
positive regulation of cell maturationGO:190343120.012
left right axis specificationGO:007098610.012
protein homooligomerizationGO:005126070.012
ribonucleoside triphosphate metabolic processGO:00091991190.012
phospholipid transportGO:001591420.012
negative regulation of catabolic processGO:0009895360.012
receptor mediated endocytosisGO:0006898210.012
endocytosisGO:00068973100.011
embryonic organ developmentGO:0048568500.011
negative regulation of purine nucleotide catabolic processGO:003312210.011
regulation of mapk cascadeGO:0043408920.011
regulation of response to stressGO:00801342000.011
positive regulation of neuron projection regenerationGO:007057230.011
regulation of rap gtpase activityGO:003231730.011
imaginal disc derived male genitalia morphogenesisGO:0048803140.011
regulation of programmed cell deathGO:00430671520.011
reproductive structure developmentGO:0048608740.011
Worm
regulation of cell proliferation involved in compound eye morphogenesisGO:200049520.011
purine nucleotide metabolic processGO:00061631460.011
amine metabolic processGO:0009308120.011
negative regulation of mitotic sister chromatid separationGO:2000816130.011
regulation of rna stabilityGO:004348740.011
oocyte fate commitmentGO:004860020.011
muscle organ developmentGO:00075171270.011
regulation of dna methylationGO:004403030.010
anatomical structure homeostasisGO:0060249970.010
embryonic digestive tract developmentGO:004856650.010
mitotic g2 dna damage checkpointGO:0007095690.010
meiotic nuclear envelope disassemblyGO:005107820.010
appendage morphogenesisGO:00351073970.010
specification of segmental identity antennal segmentGO:000738320.010
purine ribonucleoside monophosphate catabolic processGO:0009169380.010
positive regulation of proteolysisGO:0045862520.010
negative regulation of stem cell proliferationGO:2000647300.010
telomere maintenanceGO:0000723210.010
positive regulation of pole plasm oskar mrna localizationGO:004585620.010
purine containing compound metabolic processGO:00725211550.010

Su(var)205 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
connective tissue diseaseDOID:6500.038
bone diseaseDOID:008000100.038
disease of anatomical entityDOID:700.038
brachydactylyDOID:005058100.038
dysostosisDOID:193400.038
musculoskeletal system diseaseDOID:1700.038
bone development diseaseDOID:008000600.038
disease of cellular proliferationDOID:1456600.016
nervous system benign neoplasmDOID:006011500.016
organ system benign neoplasmDOID:006008500.016
benign neoplasmDOID:006007200.016
neuromaDOID:200100.016
cancerDOID:16200.015
organ system cancerDOID:005068600.015
endocrine gland cancerDOID:17000.015
thyroid cancerDOID:178100.015
syndromeDOID:22500.013