Drosophila melanogaster

69 known processes

sif (Dmel_CG34418)

still life

(Aliases: CG34418,RhoGEF,Dmel_CG32414,Dmel_CG5406,Dmel\CG34418,CG5406,SIF,CG32414,CG5256,slf,Sif)

sif biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
adult locomotory behaviorGO:0008344760.689
synapse organizationGO:00508081960.391
dendrite developmentGO:00163582040.357
regulation of cellular component biogenesisGO:00440872010.266
cell projection assemblyGO:0030031940.205
cell cell signaling involved in cell fate commitmentGO:00451682100.197
synaptic growth at neuromuscular junctionGO:00511241190.184
axonogenesisGO:00074092900.149
establishment of localization in cellGO:00516494020.149
neuromuscular junction developmentGO:00075281490.139
growthGO:00400073590.137
regulation of localizationGO:00328792750.126
vesicle mediated transportGO:00161923810.126
locomotory behaviorGO:00076261760.125
regulation of multicellular organismal developmentGO:20000264140.124
dendrite morphogenesisGO:00488131990.123
neuron neuron synaptic transmissionGO:0007270140.121
synapse assemblyGO:00074161430.119
establishment of synaptic vesicle localizationGO:0097480500.117
neurological system processGO:00508773580.117
regulation of synapse assemblyGO:0051963940.107
adult behaviorGO:00305341370.107
eye developmentGO:00016543230.106
protein modification processGO:00362114380.104
lateral inhibitionGO:00463312060.102
cell cell adhesion via plasma membrane adhesion moleculesGO:0098742260.101
sensory perceptionGO:00076001960.092
synaptic vesicle localizationGO:0097479530.084
small molecule metabolic processGO:00442813050.076
Human Mouse
cell recognitionGO:00080371020.074
photoreceptor cell differentiationGO:00465301700.073
establishment of vesicle localizationGO:0051650510.072
positive regulation of nitrogen compound metabolic processGO:00511733540.071
Human Mouse
cellular protein modification processGO:00064644380.069
neuron projection guidanceGO:00974852410.069
compound eye developmentGO:00487493070.069
synaptic transmissionGO:00072682880.069
positive regulation of rna metabolic processGO:00512542710.069
aromatic compound catabolic processGO:00194391660.068
Human Mouse
positive regulation of rna biosynthetic processGO:19026802660.067
regulation of synapse organizationGO:00508071100.067
regulation of molecular functionGO:00650092170.066
Human Mouse
single organism intracellular transportGO:19025822070.066
regulation of anatomical structure morphogenesisGO:00226032420.064
epithelial cell developmentGO:00020642740.061
receptor clusteringGO:004311330.061
regulation of cell differentiationGO:00455953020.059
regulation of cell projection assemblyGO:0060491300.059
establishment of organelle localizationGO:00516561220.058
regulation of cell developmentGO:00602842150.056
regulation of epithelial cell proliferationGO:005067840.056
enzyme linked receptor protein signaling pathwayGO:00071671790.056
Mouse
regulation of protein metabolic processGO:00512462560.055
cell growthGO:00160491080.055
negative regulation of gene expressionGO:00106293870.055
regulation of nervous system developmentGO:00519602480.054
positive regulation of macromolecule metabolic processGO:00106044050.054
appendage morphogenesisGO:00351073970.054
protein complex biogenesisGO:00702712010.053
regulation of cell deathGO:00109411730.053
guanosine containing compound catabolic processGO:1901069740.052
Human Mouse
developmental growthGO:00485892800.052
deathGO:00162652840.052
transcription from rna polymerase ii promoterGO:00063663680.052
microtubule based transportGO:0010970420.050
protein complex assemblyGO:00064612000.050
intracellular transportGO:00469072280.049
regulation of developmental growthGO:00486381740.049
macromolecular complex assemblyGO:00650032560.049
single organism membrane organizationGO:0044802930.049
neuron recognitionGO:00080381010.048
regionalizationGO:00030024160.048
positive regulation of macromolecule biosynthetic processGO:00105572830.048
regulation of transcription from rna polymerase ii promoterGO:00063573780.047
regulation of neuron projection developmentGO:0010975690.047
single organism cellular localizationGO:19025801800.047
secretion by cellGO:00329401010.045
developmental growth involved in morphogenesisGO:0060560650.045
positive regulation of signalingGO:00230562430.044
cell adhesionGO:00071551360.044
Human
regulation of growthGO:00400082330.043
organonitrogen compound metabolic processGO:19015643180.041
Human Mouse
protein maturationGO:0051604710.041
synaptic vesicle recyclingGO:0036465280.041
sensory organ morphogenesisGO:00905962600.041
response to organic substanceGO:00100332840.040
single organism cell adhesionGO:0098602470.040
positive regulation of cellular component biogenesisGO:0044089800.040
regulation of organelle organizationGO:00330431960.039
multi organism behaviorGO:00517051750.039
membrane depolarizationGO:005189940.039
organic substance transportGO:00717022570.038
cell deathGO:00082192790.038
purine nucleoside triphosphate catabolic processGO:00091461080.038
Human Mouse
regulation of excitatory postsynaptic membrane potentialGO:006007930.038
gtp metabolic processGO:0046039720.038
Human Mouse
establishment of protein localizationGO:00451841630.037
positive regulation of cell projection organizationGO:0031346290.037
actin filament organizationGO:00070151260.036
ribonucleoside metabolic processGO:00091191270.036
Human Mouse
cellular macromolecule localizationGO:00707272200.035
proteolysisGO:00065081920.035
regulation of synapse structure and activityGO:00508031280.035
positive regulation of cellular component organizationGO:00511301560.034
neurotransmitter secretionGO:0007269350.034
regulation of vesicle mediated transportGO:0060627590.034
endocytosisGO:00068973100.034
catabolic processGO:00090564090.034
Human Mouse
synaptic vesicle transportGO:0048489500.034
positive regulation of cellular protein metabolic processGO:00322701180.034
cell maturationGO:00484691440.034
regulation of cytoskeleton organizationGO:0051493890.034
organelle localizationGO:00516401480.034
neuromuscular synaptic transmissionGO:0007274670.033
actin cytoskeleton organizationGO:00300362060.033
membrane organizationGO:00610241120.033
protein heterooligomerizationGO:005129140.033
terminal button organizationGO:0072553190.033
organic substance catabolic processGO:19015753080.033
Human Mouse
phosphorylationGO:00163102940.033
tissue morphogenesisGO:00487292970.033
single organism behaviorGO:00447083910.032
regulation of anatomical structure sizeGO:00900661630.032
compound eye morphogenesisGO:00017452490.031
columnar cuboidal epithelial cell developmentGO:00020662490.031
purine nucleotide catabolic processGO:00061951090.031
Human Mouse
regulation of neurogenesisGO:00507671580.031
epithelial cell differentiationGO:00308553220.031
oxoacid metabolic processGO:00434361030.030
organic cyclic compound catabolic processGO:19013611680.030
Human Mouse
positive regulation of cell communicationGO:00106472500.030
developmental cell growthGO:0048588520.030
positive regulation of protein metabolic processGO:00512471280.030
muscle structure developmentGO:00610612240.030
columnar cuboidal epithelial cell differentiationGO:00020652560.030
regulation of cellular localizationGO:00603411360.029
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.029
Mouse
oocyte developmentGO:00485991240.029
cellular macromolecular complex assemblyGO:00346221530.029
response to biotic stimulusGO:00096072940.029
nucleobase containing compound catabolic processGO:00346551650.029
Human Mouse
blastoderm segmentationGO:00073501590.029
purine ribonucleoside metabolic processGO:00461281270.029
Human Mouse
gtp catabolic processGO:0006184720.029
Human Mouse
regulation of glutamate receptor signaling pathwayGO:190044910.028
cellular amino acid metabolic processGO:0006520610.028
cellular component assembly involved in morphogenesisGO:00109271510.028
regulation of cellular protein metabolic processGO:00322682430.028
purine containing compound catabolic processGO:00725231120.028
Human Mouse
developmental maturationGO:00217001720.028
response to light stimulusGO:00094161240.028
learning or memoryGO:00076111410.028
positive regulation of signal transductionGO:00099672230.028
tripartite regional subdivisionGO:00073511030.028
nucleoside phosphate catabolic processGO:19012921100.028
Human Mouse
positive regulation of exocytosisGO:004592140.028
eye morphogenesisGO:00485922600.027
cytokinesisGO:0000910900.027
ribonucleoside catabolic processGO:00424541120.027
Human Mouse
intraspecies interaction between organismsGO:005170340.027
anterior posterior axis specification embryoGO:00085951030.027
cellular catabolic processGO:00442483720.027
Human Mouse
cell divisionGO:00513012480.027
positive regulation of nucleic acid templated transcriptionGO:19035082660.027
protein localizationGO:00081042840.026
positive regulation of gene expressionGO:00106282900.026
immune responseGO:00069552460.026
positive regulation of developmental processGO:00510941430.026
Mouse
male gamete generationGO:00482322010.026
imaginal disc derived appendage morphogenesisGO:00351143950.026
nucleoside triphosphate metabolic processGO:00091411200.025
Human Mouse
protein transportGO:00150311550.025
positive regulation of nucleobase containing compound metabolic processGO:00459353320.025
Human Mouse
positive regulation of transportGO:0051050920.025
epithelium migrationGO:00901321480.025
ion transportGO:00068111450.025
multi multicellular organism processGO:00447061230.025
programmed cell deathGO:00125012570.024
positive regulation of transcription dna templatedGO:00458932660.024
positive regulation of secretion by cellGO:1903532200.024
protein processingGO:0016485680.024
single organism catabolic processGO:00447122280.024
Human Mouse
regulation of endocytosisGO:0030100370.024
positive regulation of response to stimulusGO:00485843230.024
positive regulation of multicellular organismal processGO:00512401430.023
Mouse
vesicle localizationGO:0051648550.023
synaptic vesicle endocytosisGO:0048488280.023
regulation of catabolic processGO:00098941700.023
Human Mouse
embryonic pattern specificationGO:00098801740.023
negative regulation of multicellular organismal processGO:00512411420.023
intracellular protein transportGO:00068861040.023
axis specificationGO:00097981670.023
positive regulation of phosphorus metabolic processGO:00105621390.023
Human Mouse
imaginal disc derived appendage developmentGO:00487373990.023
glycosyl compound catabolic processGO:19016581120.022
Human Mouse
regulation of response to stressGO:00801342000.022
regulation of cellular catabolic processGO:00313291570.022
Human Mouse
cognitionGO:00508901410.022
organonitrogen compound catabolic processGO:19015651280.022
Human Mouse
ribonucleotide catabolic processGO:00092611090.022
Human Mouse
sensory perception of mechanical stimulusGO:0050954720.022
amine metabolic processGO:0009308120.022
social behaviorGO:003517640.022
embryo development ending in birth or egg hatchingGO:00097921520.022
cellular ketone metabolic processGO:0042180240.022
protein modification by small protein conjugationGO:0032446790.022
regulation of immune system processGO:00026821760.022
negative regulation of growthGO:0045926840.022
positive regulation of neurotransmitter secretionGO:000195620.022
appendage developmentGO:00487364010.021
regulation of cellular component sizeGO:0032535980.021
spermatogenesisGO:00072832000.021
carboxylic acid metabolic processGO:0019752920.021
regulation of intracellular signal transductionGO:19025312360.021
Human Mouse
purine nucleoside triphosphate metabolic processGO:00091441190.021
Human Mouse
dna metabolic processGO:00062592270.021
regulation of ion transmembrane transportGO:0034765270.021
rho protein signal transductionGO:0007266140.021
imaginal disc derived wing morphogenesisGO:00074763370.021
organophosphate catabolic processGO:00464341120.021
Human Mouse
regulation of catalytic activityGO:00507901850.021
Human Mouse
cilium morphogenesisGO:0060271390.021
ribonucleoside triphosphate catabolic processGO:00092031080.021
Human Mouse
forebrain developmentGO:003090020.020
ameboidal type cell migrationGO:00016671510.020
purine ribonucleoside triphosphate catabolic processGO:00092071080.020
Human Mouse
phagocytosisGO:00069092150.020
response to bacteriumGO:00096171980.020
regulation of cell morphogenesis involved in differentiationGO:0010769610.020
regulation of synaptic growth at neuromuscular junctionGO:0008582890.020
central nervous system developmentGO:00074172010.020
embryonic development via the syncytial blastodermGO:00017001480.020
secretionGO:00469031090.020
signal releaseGO:0023061490.020
tissue homeostasisGO:0001894360.020
nucleoside catabolic processGO:00091641120.020
Human Mouse
negative regulation of cellular component organizationGO:00511291080.020
endomembrane system organizationGO:00102561190.020
regulation of neurotransmitter levelsGO:0001505380.020
photoreceptor cell developmentGO:0042461960.020
negative regulation of response to stimulusGO:00485852580.019
positive regulation of cell developmentGO:0010720610.019
Mouse
positive regulation of biosynthetic processGO:00098913160.019
ovarian follicle cell developmentGO:00307072480.019
carbohydrate derivative catabolic processGO:19011361180.019
Human Mouse
nucleobase containing small molecule metabolic processGO:00550861740.019
Human Mouse
wing disc morphogenesisGO:00074723440.019
meiotic cell cycleGO:00513211710.018
retina development in camera type eyeGO:006004140.018
eye photoreceptor cell developmentGO:0042462810.018
purine ribonucleoside triphosphate metabolic processGO:00092051190.018
Human Mouse
innate immune responseGO:00450871440.018
intracellular signal transductionGO:00355563000.018
Human Mouse
immune system processGO:00023763470.018
embryonic axis specificationGO:00005781070.018
biological adhesionGO:00226101380.018
Human
filopodium assemblyGO:0046847330.018
sensory perception of soundGO:0007605560.018
heterocycle catabolic processGO:00467001660.018
Human Mouse
border follicle cell migrationGO:00072981130.018
stress activated protein kinase signaling cascadeGO:0031098550.018
regulation of ras protein signal transductionGO:0046578930.018
Human Mouse
regulation of cell cycle processGO:00105641810.018
nucleoside triphosphate catabolic processGO:00091431080.018
Human Mouse
mrna processingGO:00063971040.017
organic acid metabolic processGO:00060821030.017
cellularizationGO:0007349900.017
regulation of peptidase activityGO:0052547390.017
chemotaxisGO:00069352490.017
epithelial cell migrationGO:00106311480.017
embryonic morphogenesisGO:00485982060.017
positive regulation of intracellular signal transductionGO:19025331160.017
localization of cellGO:00516742570.017
Human
cellular nitrogen compound catabolic processGO:00442701650.017
Human Mouse
cell proliferationGO:00082832990.017
synaptic vesicle exocytosisGO:0016079160.017
sensory perception of painGO:001923340.017
regulation of embryonic developmentGO:0045995680.017
carbohydrate derivative metabolic processGO:19011352170.017
Human Mouse
cilium organizationGO:0044782410.017
tissue migrationGO:00901301550.017
regulation of cellular amine metabolic processGO:003323830.017
negative regulation of signalingGO:00230572190.017
protein phosphorylationGO:00064681690.017
axon developmentGO:00615642970.016
purine nucleotide metabolic processGO:00061631460.016
Human Mouse
mrna metabolic processGO:00160711240.016
regulation of receptor activityGO:0010469100.016
neurotransmitter transportGO:0006836370.016
organelle assemblyGO:00709251980.016
negative regulation of cell deathGO:0060548810.016
exocrine system developmentGO:00352721620.016
positive regulation of molecular functionGO:00440931360.016
Human Mouse
positive regulation of phosphorylationGO:0042327870.016
peptidyl amino acid modificationGO:00181931050.016
axon extensionGO:0048675320.016
protein ubiquitinationGO:0016567700.016
compound eye photoreceptor cell differentiationGO:00017511400.016
regulation of hydrolase activityGO:0051336970.016
Human Mouse
negative regulation of signal transductionGO:00099682060.016
positive regulation of cellular biosynthetic processGO:00313283160.016
single organismal cell cell adhesionGO:0016337450.016
regulation of cell projection organizationGO:0031344920.016
anion homeostasisGO:005508130.016
regulation of cell shapeGO:00083601130.016
cytoskeleton dependent cytokinesisGO:0061640810.016
regulation of cell morphogenesisGO:00226041630.016
mushroom body developmentGO:0016319700.015
defense responseGO:00069523000.015
small gtpase mediated signal transductionGO:0007264880.015
Human Mouse
regulation of mitotic cell cycle phase transitionGO:19019901300.015
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.015
synaptic transmission glutamatergicGO:003524970.015
nucleoside metabolic processGO:00091161270.015
Human Mouse
response to alcoholGO:0097305950.015
positive regulation of proteolysisGO:0045862520.015
cell migrationGO:00164772380.015
Human
posttranscriptional regulation of gene expressionGO:00106081450.015
chromatin assemblyGO:0031497480.015
regulation of transportGO:00510491810.015
eye photoreceptor cell differentiationGO:00017541450.015
exocytosisGO:0006887280.015
organophosphate metabolic processGO:00196371950.015
Human Mouse
defense response to other organismGO:00985422250.015
nucleotide catabolic processGO:00091661090.015
Human Mouse
positive regulation of synaptic vesicle endocytosisGO:190024440.015
regulation of transmembrane transportGO:0034762270.015
cellular protein complex assemblyGO:0043623710.015
anterior posterior axis specificationGO:00099481090.015
epithelial tube morphogenesisGO:0060562880.015
regulation of dendrite developmentGO:0050773370.015
positive regulation of lipid storageGO:001088440.015
regulation of lipid storageGO:0010883220.015
regulation of neuron differentiationGO:00456641030.015
regulation of mitotic cell cycleGO:00073461900.015
rhythmic synaptic transmissionGO:006002420.015
post embryonic appendage morphogenesisGO:00351203850.015
purine nucleoside catabolic processGO:00061521120.014
Human Mouse
morphogenesis of an epitheliumGO:00020092760.014
developmental programmed cell deathGO:00106231380.014
regulation of membrane potentialGO:0042391350.014
telencephalon developmentGO:002153720.014
positive regulation of synaptic transmissionGO:0050806150.014
regulation of secretionGO:0051046440.014
microtubule based movementGO:0007018510.014
glycosyl compound metabolic processGO:19016571270.014
Human Mouse
taxisGO:00423303040.014
positive regulation of synapse assemblyGO:0051965290.014
striated muscle tissue developmentGO:0014706270.014
positive regulation of endocytosisGO:0045807220.014
negative regulation of developmental processGO:00510932010.014
convergent extensionGO:006002620.014
regulation of protein modification processGO:00313991120.014
negative regulation of cellular metabolic processGO:00313243820.014
morphogenesis of embryonic epitheliumGO:0016331940.014
regulation of ras gtpase activityGO:0032318380.014
Human Mouse
response to external biotic stimulusGO:00432072930.014
regulation of apoptotic processGO:00429811300.014
purine ribonucleoside catabolic processGO:00461301120.014
Human Mouse
jnk cascadeGO:0007254500.014
vesicle organizationGO:0016050440.014
response to oxygen containing compoundGO:19017002000.013
purine nucleoside metabolic processGO:00422781270.013
Human Mouse
negative regulation of developmental growthGO:0048640640.013
nucleoside phosphate metabolic processGO:00067531620.013
Human Mouse
dna packagingGO:0006323910.013
chromosome organizationGO:00512763600.013
regulation of nucleoside metabolic processGO:0009118500.013
Human Mouse
maintenance of locationGO:0051235730.013
regulation of cell cycle phase transitionGO:19019871300.013
regulation of cellular ketone metabolic processGO:001056530.013
positive regulation of catalytic activityGO:00430851180.013
Human Mouse
regulation of cellular amino acid metabolic processGO:000652100.013
regulation of neuron deathGO:1901214260.013
positive regulation of protein modification processGO:0031401580.013
jak stat cascadeGO:0007259490.013
dorsal closureGO:0007391790.013
positive regulation of hydrolase activityGO:0051345780.013
Human Mouse
apoptotic processGO:00069151590.013
eye antennal disc developmentGO:0035214600.013
regulation of actin cytoskeleton organizationGO:0032956420.013
protein polymerizationGO:0051258420.012
cellular amine metabolic processGO:0044106120.012
cortical cytoskeleton organizationGO:0030865290.012
regulation of small gtpase mediated signal transductionGO:0051056930.012
Human Mouse
positive regulation of secretionGO:0051047220.012
regulation of programmed cell deathGO:00430671520.012
tube morphogenesisGO:00352391910.012
protein localization to membraneGO:0072657190.012
chromatin remodelingGO:0006338720.012
regulation of cell sizeGO:0008361630.012
negative regulation of gene expression epigeneticGO:0045814770.012
muscle organ developmentGO:00075171270.012
stress activated mapk cascadeGO:0051403520.012
spermatid developmentGO:0007286980.012
protein modification by small protein conjugation or removalGO:00706471060.012
regulation of actin filament based processGO:0032970420.012
positive regulation of gtp catabolic processGO:0033126430.012
Human Mouse
cilium assemblyGO:0042384380.012
negative regulation of nervous system developmentGO:0051961920.012
negative regulation of cell communicationGO:00106482230.012
positive regulation of ras gtpase activityGO:0032320360.012
Human
spermatid differentiationGO:00485151140.012
salivary gland developmentGO:00074311620.012
neuron maturationGO:0042551310.012
regulation of nucleotide catabolic processGO:0030811480.012
Human Mouse
dna conformation changeGO:00711031050.012
response to ethanolGO:0045471590.012
tissue deathGO:00162711020.012
negative regulation of programmed cell deathGO:0043069720.012
dorsal ventral pattern formationGO:00099531330.012
regulation of secretion by cellGO:1903530390.012
nitrogen compound transportGO:0071705850.011
calcium dependent cell cell adhesion via plasma membrane cell adhesion moleculesGO:001633990.011
nucleus organizationGO:0006997450.011
positive regulation of developmental growthGO:0048639620.011
compound eye photoreceptor developmentGO:0042051780.011
lipid localizationGO:0010876540.011
cell fate determinationGO:0001709910.011
cytoskeleton dependent intracellular transportGO:0030705440.011
ovarian follicle cell migrationGO:00072971210.011
cardiovascular system developmentGO:0072358820.011
hindgut morphogenesisGO:0007442580.011
segmentationGO:00352822070.011
rna localizationGO:00064031150.011
intracellular mrna localization involved in pattern specification processGO:0060810560.011
negative regulation of nitrogen compound metabolic processGO:00511722650.011
defense response to bacteriumGO:00427421780.011
negative regulation of biosynthetic processGO:00098902770.011
transmembrane transportGO:00550851390.011
positive regulation of cell deathGO:0010942690.011
ras protein signal transductionGO:0007265880.011
Human
regulation of cell cycleGO:00517262910.011
negative regulation of cell differentiationGO:00455961430.011
transition metal ion homeostasisGO:0055076170.011
actin filament based processGO:00300292200.011
positive regulation of nucleoside metabolic processGO:0045979470.011
Human Mouse
digestive tract developmentGO:00485651490.011
regulation of gene expression epigeneticGO:00400291280.011
centrosome organizationGO:00512971630.010
organelle fissionGO:00482853400.010
regulation of ion transportGO:0043269390.010
anterior posterior pattern specificationGO:00099521360.010
histolysisGO:00075591020.010
ribonucleoside triphosphate metabolic processGO:00091991190.010
Human Mouse
regulation of gtp catabolic processGO:0033124440.010
Human Mouse
regulation of immune responseGO:00507761180.010
associative learningGO:0008306650.010
positive regulation of protein phosphorylationGO:0001934340.010
protein targetingGO:0006605640.010
positive regulation of synaptic growth at neuromuscular junctionGO:0045887260.010
regulation of transmembrane transporter activityGO:002289860.010

sif disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.026
disease of cellular proliferationDOID:1456600.019
cancerDOID:16200.019
organ system cancerDOID:005068600.019
nervous system diseaseDOID:86300.019
sensory system diseaseDOID:005015500.012