IMP: Integrative Multi-species Prediction

Drosophila melanogaster

16 known processes

CHIP (Dmel_CG5203)

CG5203 gene product from transcript CG5203-RA

(Aliases: Dmel\CG5203,CG5203,Chip,dCHIP)

FLYBASE: FBgn0027052
Entrez: 34433
UniProtKB: Q9XYW6

Process Predictions
Disease Predictions

CHIP biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability
regulation of cell differentiation	GO:0045595	302	0.129
regulation of multicellular organismal development	GO:2000026	414	0.117
cellular protein modification process	GO:0006464	438	0.103
regulation of cell development	GO:0060284	215	0.089
neurological system process	GO:0050877	358	0.080
response to biotic stimulus	GO:0009607	294	0.069
defense response to bacterium	GO:0042742	178	0.058
response to external biotic stimulus	GO:0043207	293	0.054
eye development	GO:0001654	323	0.053
intracellular signal transduction	GO:0035556	300	0.049
regulation of response to stress	GO:0080134	200	0.049
organelle assembly	GO:0070925	198	0.049
defense response	GO:0006952	300	0.048
spermatogenesis	GO:0007283	200	0.048
single organism intracellular transport	GO:1902582	207	0.048
ameboidal type cell migration	GO:0001667	151	0.047
endocytosis	GO:0006897	310	0.047
camera type eye development	GO:0043010	4	0.047
negative regulation of cellular biosynthetic process	GO:0031327	277	0.046
biological adhesion	GO:0022610	138	0.046
cellular catabolic process	GO:0044248	372	0.046
negative regulation of rna biosynthetic process	GO:1902679	240	0.046
localization of cell	GO:0051674	257	0.046
regulation of neuron differentiation	GO:0045664	103	0.044
response to other organism	GO:0051707	293	0.043
macromolecular complex assembly	GO:0065003	256	0.042
wing disc morphogenesis	GO:0007472	344	0.042
actin filament based process	GO:0030029	220	0.041
protein catabolic process	GO:0030163	101	0.041
single organism carbohydrate metabolic process	GO:0044723	72	0.038
chromatin organization	GO:0006325	207	0.038
body morphogenesis	GO:0010171	2	0.037
central nervous system development	GO:0007417	201	0.035
growth	GO:0040007	359	0.034
actin cytoskeleton organization	GO:0030036	206	0.034
positive regulation of response to stimulus	GO:0048584	323	0.033
protein modification process	GO:0036211	438	0.032
cell adhesion	GO:0007155	136	0.031
cell motility	GO:0048870	251	0.031
muscle structure development	GO:0061061	224	0.031
positive regulation of i kappab kinase nf kappab signaling	GO:0043123	1	0.031
phagocytosis	GO:0006909	215	0.030
immune response	GO:0006955	246	0.030
forebrain development	GO:0030900	2	0.029
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.029
regulation of nervous system development	GO:0051960	248	0.028
post embryonic appendage morphogenesis	GO:0035120	385	0.026
epithelial cell development	GO:0002064	274	0.026
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.025
lateral inhibition	GO:0046331	206	0.025
organic substance catabolic process	GO:1901575	308	0.025
cell cell junction organization	GO:0045216	55	0.024
establishment of localization in cell	GO:0051649	402	0.024
cellular macromolecule catabolic process	GO:0044265	136	0.024
vesicle mediated transport	GO:0016192	381	0.024
positive regulation of developmental process	GO:0051094	143	0.023
regulation of dendrite development	GO:0050773	37	0.023
eye morphogenesis	GO:0048592	260	0.022
nuclear division	GO:0000280	332	0.022
immune system process	GO:0002376	347	0.022
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.022
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.022
imaginal disc growth	GO:0007446	37	0.021
intracellular transport	GO:0046907	228	0.021
dendrite morphogenesis	GO:0048813	199	0.021
negative regulation of multicellular organismal process	GO:0051241	142	0.021
proteolysis	GO:0006508	192	0.020
sensory organ morphogenesis	GO:0090596	260	0.020
dendrite development	GO:0016358	204	0.020
circulatory system development	GO:0072359	82	0.020
negative regulation of signal transduction	GO:0009968	206	0.019
response to starvation	GO:0042594	97	0.019
proteolysis involved in cellular protein catabolic process	GO:0051603	83	0.019
imaginal disc derived appendage development	GO:0048737	399	0.019
retrograde transport endosome to golgi	GO:0042147	3	0.019
negative regulation of transcription dna templated	GO:0045892	237	0.019
cellular protein catabolic process	GO:0044257	83	0.019
male meiosis cytokinesis	GO:0007112	26	0.019
negative regulation of cell death	GO:0060548	81	0.019
negative regulation of apoptotic process	GO:0043066	63	0.018
compound eye development	GO:0048749	307	0.018
cuticle development	GO:0042335	86	0.018
organonitrogen compound metabolic process	GO:1901564	318	0.018
regulation of proteasomal ubiquitin dependent protein catabolic process	GO:0032434	37	0.017
response to wounding	GO:0009611	94	0.017
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.017
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.017
phosphorylation	GO:0016310	294	0.017
compound eye photoreceptor cell differentiation	GO:0001751	140	0.017
modification dependent protein catabolic process	GO:0019941	78	0.016
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.016
negative regulation of programmed cell death	GO:0043069	72	0.016
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.016
macromolecule catabolic process	GO:0009057	161	0.016
defense response to other organism	GO:0098542	225	0.016
protein modification by small protein conjugation or removal	GO:0070647	106	0.016
epithelial cell differentiation	GO:0030855	322	0.016
cell migration	GO:0016477	238	0.016
regulation of defense response	GO:0031347	102	0.016
stem cell development	GO:0048864	79	0.016
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.016
negative regulation of developmental process	GO:0051093	201	0.016
gastrulation	GO:0007369	70	0.015
negative regulation of cellular metabolic process	GO:0031324	382	0.015
protein phosphorylation	GO:0006468	169	0.015
catabolic process	GO:0009056	409	0.015
regulation of hemocyte proliferation	GO:0035206	37	0.015
regulation of intracellular signal transduction	GO:1902531	236	0.015
regulation of phosphatase activity	GO:0010921	3	0.015
regulation of cellular response to stress	GO:0080135	89	0.015
cellular nitrogen compound catabolic process	GO:0044270	165	0.015
microtubule organizing center organization	GO:0031023	168	0.014
immune system development	GO:0002520	57	0.014
ubiquitin dependent protein catabolic process	GO:0006511	78	0.014
negative regulation of rna metabolic process	GO:0051253	251	0.014
cellular macromolecular complex assembly	GO:0034622	153	0.014
adherens junction organization	GO:0034332	27	0.013
cell aging	GO:0007569	2	0.013
positive regulation of signal transduction	GO:0009967	223	0.013
establishment or maintenance of cell polarity	GO:0007163	167	0.013
regulation of developmental growth	GO:0048638	174	0.013
meiotic cell cycle process	GO:1903046	132	0.013
cognition	GO:0050890	141	0.013
membrane organization	GO:0061024	112	0.013
regulation of anatomical structure morphogenesis	GO:0022603	242	0.012
locomotory behavior	GO:0007626	176	0.012
germ line stem cell maintenance	GO:0030718	50	0.012
negative regulation of cell differentiation	GO:0045596	143	0.012
cellular response to radiation	GO:0071478	52	0.012
regulation of molecular function	GO:0065009	217	0.012
response to abiotic stimulus	GO:0009628	341	0.012
muscle organ development	GO:0007517	127	0.012
photoreceptor cell development	GO:0042461	96	0.012
developmental growth	GO:0048589	280	0.012
taxis	GO:0042330	304	0.011
positive regulation of rna metabolic process	GO:0051254	271	0.011
single organism biosynthetic process	GO:0044711	206	0.011
humoral immune response	GO:0006959	117	0.011
eye photoreceptor cell development	GO:0042462	81	0.011
negative regulation of signaling	GO:0023057	219	0.011
modification dependent macromolecule catabolic process	GO:0043632	79	0.011
positive regulation of cgmp metabolic process	GO:0030825	1	0.011
positive regulation of growth	GO:0045927	75	0.011
centrosome organization	GO:0051297	163	0.011
negative regulation of biosynthetic process	GO:0009890	277	0.011
muscle cell fate commitment	GO:0042693	14	0.010
negative regulation of sequestering of calcium ion	GO:0051283	2	0.010
positive regulation of molecular function	GO:0044093	136	0.010
regulation of neuron projection development	GO:0010975	69	0.010
endosomal transport	GO:0016197	44	0.010
cell death	GO:0008219	279	0.010
regulation of cell projection organization	GO:0031344	92	0.010
muscle cell differentiation	GO:0042692	103	0.010
negative regulation of cellular protein metabolic process	GO:0032269	85	0.010

CHIP disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.012

Loading network...

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network