Drosophila melanogaster

56 known processes

SMC2 (Dmel_CG10212)

CG10212 gene product from transcript CG10212-RA

(Aliases: DmSMC2,Dmel\CG10212,CG10212,dSMC2)

SMC2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
chromosome organizationGO:00512763600.969
mitotic spindle organizationGO:00070522200.962
dna conformation changeGO:00711031050.918
sister chromatid segregationGO:0000819920.913
mitotic sister chromatid segregationGO:0000070870.876
spindle organizationGO:00070512530.864
chromatin modificationGO:00165681470.852
dna packagingGO:0006323910.836
mitotic sister chromatid separationGO:0051306300.801
meiotic chromosome segregationGO:0045132590.749
Mouse
chromosome segregationGO:00070591570.698
negative regulation of cellular biosynthetic processGO:00313272770.673
assembly of actomyosin apparatus involved in cytokinesisGO:0000912110.608
chromatin silencingGO:0006342760.597
dna metabolic processGO:00062592270.490
organelle fissionGO:00482853400.474
mitotic nuclear divisionGO:00070672130.469
negative regulation of nucleic acid templated transcriptionGO:19035072400.463
mitotic chromosome condensationGO:0007076220.394
metaphase plate congressionGO:0051310190.389
spindle assembly involved in mitosisGO:0090307500.357
negative regulation of rna metabolic processGO:00512532510.357
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.355
cellular component disassemblyGO:0022411460.353
negative regulation of rna biosynthetic processGO:19026792400.352
establishment of organelle localizationGO:00516561220.339
chromosome separationGO:0051304420.338
nuclear divisionGO:00002803320.336
negative regulation of gene expressionGO:00106293870.319
regulation of metaphase anaphase transition of cell cycleGO:1902099260.312
covalent chromatin modificationGO:00165691060.311
meiotic cell cycle processGO:19030461320.302
Yeast Mouse
regulation of mitotic sister chromatid segregationGO:0033047280.280
negative regulation of biosynthetic processGO:00098902770.276
negative regulation of transcription dna templatedGO:00458922370.270
organelle assemblyGO:00709251980.264
metaphase anaphase transition of cell cycleGO:0044784280.264
regulation of mitotic sister chromatid separationGO:0010965280.256
negative regulation of chromosome organizationGO:2001251190.239
chromosome condensationGO:0030261410.222
histone modificationGO:00165701060.222
negative regulation of nitrogen compound metabolic processGO:00511722650.214
Yeast
regulation of mitotic cell cycle phase transitionGO:19019901300.197
organonitrogen compound metabolic processGO:19015643180.193
Yeast
negative regulation of macromolecule biosynthetic processGO:00105582700.193
negative regulation of gene expression epigeneticGO:0045814770.190
body morphogenesisGO:001017120.187
regulation of mitotic metaphase anaphase transitionGO:0030071260.183
cytokinesisGO:0000910900.178
negative regulation of mitotic cell cycle phase transitionGO:19019911030.162
regulation of mitotic cell cycleGO:00073461900.160
eggshell chorion gene amplificationGO:000730790.156
negative regulation of cell cycle phase transitionGO:19019881030.147
negative regulation of nucleobase containing compound metabolic processGO:00459342610.145
Yeast
protein complex assemblyGO:00064612000.145
centrosome cycleGO:00070981370.138
regulation of microtubule cytoskeleton organizationGO:0070507410.137
chromatin organizationGO:00063252070.134
neuroblast proliferationGO:0007405740.127
female meiotic divisionGO:0007143700.124
defense responseGO:00069523000.123
negative regulation of mitotic sister chromatid separationGO:2000816130.122
spindle midzone assemblyGO:005125540.122
regulation of mitotic spindle organizationGO:006023690.118
negative regulation of cell cycleGO:00457861160.114
Yeast
organelle localizationGO:00516401480.113
positive regulation of nitrogen compound metabolic processGO:00511733540.107
mitotic cell cycle phase transitionGO:00447721380.105
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.102
positive regulation of nucleobase containing compound metabolic processGO:00459353320.095
g2 dna damage checkpointGO:0031572690.094
mitotic spindle elongationGO:0000022810.094
neuron recognitionGO:00080381010.090
negative regulation of mitotic cell cycleGO:00459301090.089
embryo development ending in birth or egg hatchingGO:00097921520.086
Worm
gene silencingGO:00164581380.084
cell cycle checkpointGO:0000075950.082
dendrite morphogenesisGO:00488131990.079
regulation of cell cycle phase transitionGO:19019871300.079
meiotic nuclear divisionGO:00071261510.078
Yeast Mouse
macromolecular complex assemblyGO:00650032560.075
chromatin remodelingGO:0006338720.075
dendrite developmentGO:00163582040.075
metaphase anaphase transition of mitotic cell cycleGO:0007091280.074
cellular macromolecular complex assemblyGO:00346221530.072
vesicle mediated transportGO:00161923810.072
cellular protein modification processGO:00064644380.072
lateral inhibitionGO:00463312060.070
peptidyl amino acid modificationGO:00181931050.070
negative regulation of cellular metabolic processGO:00313243820.070
Yeast
protein modification processGO:00362114380.069
regulation of cell cycleGO:00517262910.067
Yeast
negative regulation of cellular component organizationGO:00511291080.066
Yeast
regulation of chromosome organizationGO:0033044640.066
axon developmentGO:00615642970.065
regulation of organelle organizationGO:00330431960.065
Yeast
endocytosisGO:00068973100.063
axonogenesisGO:00074092900.062
meiotic cell cycleGO:00513211710.062
Yeast Mouse
cellular catabolic processGO:00442483720.061
Yeast
negative regulation of organelle organizationGO:0010639560.060
Yeast
female meiosis chromosome segregationGO:0016321330.059
regulation of microtubule polymerization or depolymerizationGO:0031110270.058
positive regulation of mitotic cell cycleGO:0045931340.058
cell proliferationGO:00082832990.057
small molecule metabolic processGO:00442813050.055
Yeast
gland developmentGO:00487321910.055
microtubule cytoskeleton organization involved in mitosisGO:1902850520.054
response to biotic stimulusGO:00096072940.053
mitotic cell cycle checkpointGO:0007093880.052
spindle assemblyGO:0051225800.052
maintenance of locationGO:0051235730.051
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:0031145300.050
regulation of gene expression epigeneticGO:00400291280.050
Worm
telomere cappingGO:0016233110.050
negative regulation of cell cycle processGO:00109481090.049
Yeast
nuclear dna replicationGO:003326010.049
chromosome localizationGO:0050000200.049
dna replicationGO:0006260480.048
regulation of microtubule based processGO:0032886490.047
chromatin assembly or disassemblyGO:0006333520.047
mitotic cytokinesisGO:0000281500.046
regulation of spindle organizationGO:0090224170.046
dna repairGO:0006281540.046
cell divisionGO:00513012480.046
Yeast
regulation of sister chromatid segregationGO:0033045280.046
deathGO:00162652840.045
dna damage checkpointGO:0000077780.044
muscle organ developmentGO:00075171270.043
regulation of neurogenesisGO:00507671580.043
negative regulation of microtubule depolymerizationGO:0007026210.043
multi multicellular organism processGO:00447061230.042
negative regulation of neuroblast proliferationGO:0007406270.041
regulation of cellular protein metabolic processGO:00322682430.041
hematopoietic stem cell differentiationGO:006021810.041
sex differentiationGO:0007548810.040
organic substance catabolic processGO:19015753080.040
Yeast
meiotic spindle organizationGO:0000212360.040
macromolecular complex disassemblyGO:0032984370.039
regulation of protein metabolic processGO:00512462560.039
heterocycle catabolic processGO:00467001660.038
Yeast
protein complex biogenesisGO:00702712010.037
regulation of chromatin silencingGO:0031935360.037
positive regulation of phosphorus metabolic processGO:00105621390.037
establishment of localization in cellGO:00516494020.036
regulation of cytoskeleton organizationGO:0051493890.036
dna biosynthetic processGO:0071897240.036
regulation of molecular functionGO:00650092170.036
dna integrity checkpointGO:0031570810.035
cell cell signaling involved in cell fate commitmentGO:00451682100.034
aromatic compound catabolic processGO:00194391660.034
Yeast
cell cycle phase transitionGO:00447701400.034
regulation of phosphate metabolic processGO:00192202100.034
response to external biotic stimulusGO:00432072930.033
regulation of catalytic activityGO:00507901850.033
rna polyadenylationGO:0043631120.032
dna replication initiationGO:000627060.032
cell deathGO:00082192790.031
lipid storageGO:0019915380.031
mitotic spindle assembly checkpointGO:0007094110.030
single organism biosynthetic processGO:00447112060.030
positive regulation of catalytic activityGO:00430851180.030
organic cyclic compound catabolic processGO:19013611680.029
Yeast
positive regulation of metaphase anaphase transition of cell cycleGO:1902101100.029
double strand break repairGO:0006302260.028
mitotic spindle stabilizationGO:004314860.028
regulation of gene silencingGO:0060968630.028
nucleobase containing compound catabolic processGO:00346551650.027
Yeast
imaginal disc derived appendage morphogenesisGO:00351143950.027
regulation of protein complex disassemblyGO:0043244290.027
regulation of proteasomal protein catabolic processGO:0061136390.027
protein complex disassemblyGO:0043241360.027
cytoskeleton dependent cytokinesisGO:0061640810.026
eggshell formationGO:00307031050.026
positive regulation of cell cycleGO:0045787430.025
cellular protein complex assemblyGO:0043623710.025
chromosome organization involved in meiosisGO:0070192100.025
Mouse
multi organism behaviorGO:00517051750.024
histone exchangeGO:0043486210.024
regulation of phosphorus metabolic processGO:00511742100.024
gonad developmentGO:0008406500.024
single organism catabolic processGO:00447122280.023
Yeast
carboxylic acid metabolic processGO:0019752920.023
nucleoside phosphate metabolic processGO:00067531620.023
Yeast
positive regulation of macromolecule metabolic processGO:00106044050.023
negative regulation of microtubule polymerization or depolymerizationGO:0031111210.022
negative regulation of mitotic metaphase anaphase transitionGO:0045841130.022
oxoacid metabolic processGO:00434361030.022
mitotic spindle checkpointGO:0071174110.021
negative regulation of sister chromatid segregationGO:0033046130.021
response to organic substanceGO:00100332840.021
spermatogenesisGO:00072832000.021
neuron projection guidanceGO:00974852410.021
negative regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032435160.021
reproductive behaviorGO:00190981220.020
regulation of protein modification processGO:00313991120.020
regulation of heterochromatin assemblyGO:003144580.020
regulation of chromatin bindingGO:003556130.020
reproductive system developmentGO:0061458740.020
chorion containing eggshell formationGO:00073041050.019
catabolic processGO:00090564090.019
Yeast
nucleotide metabolic processGO:00091171610.019
Yeast
regulation of chromosome segregationGO:0051983320.019
protein dna complex subunit organizationGO:0071824860.019
phagocytosisGO:00069092150.019
negative regulation of mitotic sister chromatid segregationGO:0033048130.018
immune responseGO:00069552460.018
chitin based larval cuticle pattern formationGO:0035293110.018
negative regulation of developmental processGO:00510932010.018
positive regulation of hydrolase activityGO:0051345780.018
nuclear migrationGO:0007097200.018
purine nucleotide catabolic processGO:00061951090.018
Yeast
imaginal disc derived appendage developmentGO:00487373990.018
gliogenesisGO:0042063800.018
protein localizationGO:00081042840.017
establishment of chromosome localizationGO:0051303200.017
response to other organismGO:00517072930.017
establishment of spindle orientationGO:0051294180.017
regulation of cytokinesisGO:003246530.017
dna replication checkpointGO:000007680.017
peptidyl threonine modificationGO:001821030.016
appendage developmentGO:00487364010.016
apoptotic processGO:00069151590.016
nucleoside metabolic processGO:00091161270.016
Yeast
protein processingGO:0016485680.016
programmed cell deathGO:00125012570.016
multi organism reproductive behaviorGO:00447051210.016
centrosome organizationGO:00512971630.016
regulation of proteolysisGO:0030162870.016
purine nucleoside triphosphate metabolic processGO:00091441190.015
Yeast
negative regulation of metaphase anaphase transition of cell cycleGO:1902100130.015
protein maturationGO:0051604710.015
negative regulation of protein metabolic processGO:0051248850.015
regulation of transcription by chromatin organizationGO:003440130.015
regulation of cellular amine metabolic processGO:003323830.015
positive regulation of mitotic metaphase anaphase transitionGO:0045842100.015
reproductive structure developmentGO:0048608740.015
axon guidanceGO:00074112330.014
spindle checkpointGO:0031577110.014
organic acid metabolic processGO:00060821030.014
negative regulation of chromosome segregationGO:0051985140.014
cellular response to dna damage stimulusGO:00069742230.014
cellular amine metabolic processGO:0044106120.014
digestive tract developmentGO:00485651490.014
protein localization to nucleusGO:0034504550.014
small gtpase mediated signal transductionGO:0007264880.014
response to alcoholGO:0097305950.014
positive regulation of cellular component biogenesisGO:0044089800.014
cellular nitrogen compound catabolic processGO:00442701650.014
Yeast
regulation of cellular amino acid metabolic processGO:000652100.014
negative regulation of nucleotide metabolic processGO:004598040.013
male meiosisGO:0007140520.013
purine nucleoside triphosphate catabolic processGO:00091461080.013
Yeast
renal tubule developmentGO:0061326640.013
actin filament based processGO:00300292200.013
nucleotide catabolic processGO:00091661090.013
Yeast
positive regulation of purine nucleotide metabolic processGO:1900544550.013
neural precursor cell proliferationGO:0061351750.013
protein dna complex assemblyGO:0065004630.013
spindle assembly checkpointGO:0071173110.013
protein depolymerizationGO:0051261310.013
regulation of mitotic spindle elongationGO:003288810.013
negative regulation of protein export from nucleusGO:004682620.013
regulation of cellular component biogenesisGO:00440872010.013
positive regulation of molecular functionGO:00440931360.013
response to heatGO:0009408630.013
carbohydrate derivative metabolic processGO:19011352170.013
Yeast
ribonucleoside metabolic processGO:00091191270.013
Yeast
cellular protein localizationGO:00346131600.013
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.012
intracellular signal transductionGO:00355563000.012
cellular ketone metabolic processGO:0042180240.012
spliceosomal snrnp assemblyGO:000038720.012
hindgut morphogenesisGO:0007442580.012
nucleoside triphosphate catabolic processGO:00091431080.012
Yeast
rna 3 end processingGO:0031123450.012
positive regulation of cellular component organizationGO:00511301560.012
cell cycle dna replicationGO:0044786230.012
nucleobase containing small molecule metabolic processGO:00550861740.012
Yeast
nucleoside triphosphate metabolic processGO:00091411200.012
Yeast
response to bacteriumGO:00096171980.012
regulation of cell deathGO:00109411730.012
positive regulation of phosphate metabolic processGO:00459371390.011
stem cell differentiationGO:00488631170.011
regulation of dna metabolic processGO:0051052340.011
amine metabolic processGO:0009308120.011
organophosphate catabolic processGO:00464341120.011
Yeast
head developmentGO:00603221350.011
positive regulation of organelle organizationGO:0010638650.011
positive regulation of chromosome segregationGO:0051984100.011
purine ribonucleoside metabolic processGO:00461281270.011
Yeast
purine nucleoside metabolic processGO:00422781270.011
Yeast
organic substance transportGO:00717022570.011
actomyosin contractile ring assemblyGO:0000915100.011
nucleoside phosphate catabolic processGO:19012921100.011
Yeast
taxisGO:00423303040.011
ras protein signal transductionGO:0007265880.011
response to sterolGO:0036314340.011
spindle elongationGO:0051231830.010
regulation of chromatin organizationGO:1902275320.010
regulation of mitosisGO:0007088560.010
histone lysine methylationGO:0034968320.010
mitotic g2 dna damage checkpointGO:0007095690.010
glycosyl compound catabolic processGO:19016581120.010
Yeast
organophosphate metabolic processGO:00196371950.010
Yeast
postreplication repairGO:000630120.010
cellular protein complex disassemblyGO:0043624350.010

SMC2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.021