IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

CG15199 (Dmel_CG15199)

CG15199 gene product from transcript CG15199-RA

(Aliases: DIGF-3,Dmel\CG15199)

FLYBASE: FBgn0030270
Entrez: 32051
UniProtKB: Q9VZ26

Process Predictions
Disease Predictions

CG15199 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
defense response to fungus	GO:0050832	48	0.146
response to ionizing radiation	GO:0010212	32	0.142
death	GO:0016265	284	0.133
defense response to other organism	GO:0098542	225	0.128
imaginal disc derived appendage development	GO:0048737	399	0.127
post embryonic appendage morphogenesis	GO:0035120	385	0.117
appendage morphogenesis	GO:0035107	397	0.116
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.114
response to temperature stimulus	GO:0009266	106	0.113
response to cold	GO:0009409	13	0.105
response to fungus	GO:0009620	50	0.104
imaginal disc derived wing morphogenesis	GO:0007476	337	0.103
appendage development	GO:0048736	401	0.098
response to reactive oxygen species	GO:0000302	24	0.097
intracellular transport	GO:0046907	228	0.097
intracellular signal transduction	GO:0035556	300	0.097
response to abiotic stimulus	GO:0009628	341	0.093
response to biotic stimulus	GO:0009607	294	0.089
cellular response to radiation	GO:0071478	52	0.089
programmed cell death	GO:0012501	257	0.080
regulation of growth	GO:0040008	233	0.077
negative regulation of cellular metabolic process	GO:0031324	382	0.074
cell death	GO:0008219	279	0.074
response to starvation	GO:0042594	97	0.073
response to heat	GO:0009408	63	0.070
defense response to bacterium	GO:0042742	178	0.068
macromolecular complex assembly	GO:0065003	256	0.066
establishment of localization in cell	GO:0051649	402	0.065
cellular response to abiotic stimulus	GO:0071214	58	0.065
defense response	GO:0006952	300	0.062
stress activated mapk cascade	GO:0051403	52	0.060
protein complex assembly	GO:0006461	200	0.059
microtubule polymerization or depolymerization	GO:0031109	39	0.058
response to organic substance	GO:0010033	284	0.056
stress activated protein kinase signaling cascade	GO:0031098	55	0.055
signal transduction by phosphorylation	GO:0023014	107	0.054
reactive oxygen species metabolic process	GO:0072593	22	0.053
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.053
response to nutrient levels	GO:0031667	114	0.051
organonitrogen compound metabolic process	GO:1901564	318	0.051
multicellular organismal aging	GO:0010259	140	0.050
regulation of localization	GO:0032879	275	0.049
response to other organism	GO:0051707	293	0.049
response to radiation	GO:0009314	155	0.047
triglyceride catabolic process	GO:0019433	3	0.047
sensory perception	GO:0007600	196	0.046
response to hydrogen peroxide	GO:0042542	11	0.046
response to bacterium	GO:0009617	198	0.046
regulation of cell death	GO:0010941	173	0.046
small molecule metabolic process	GO:0044281	305	0.045
negative regulation of growth	GO:0045926	84	0.045
neurological system process	GO:0050877	358	0.044
catabolic process	GO:0009056	409	0.044
response to external biotic stimulus	GO:0043207	293	0.043
cellular catabolic process	GO:0044248	372	0.042
visual perception	GO:0007601	9	0.041
endocytosis	GO:0006897	310	0.041
response to extracellular stimulus	GO:0009991	116	0.039
cell growth	GO:0016049	108	0.039
determination of adult lifespan	GO:0008340	137	0.039
regulation of intracellular transport	GO:0032386	64	0.039
regulation of programmed cell death	GO:0043067	152	0.038
vesicle mediated transport	GO:0016192	381	0.037
regulation of cell growth	GO:0001558	43	0.036
response to oxygen containing compound	GO:1901700	200	0.036
lateral inhibition	GO:0046331	206	0.035
response to alcohol	GO:0097305	95	0.034
negative regulation of cell death	GO:0060548	81	0.033
phagocytosis	GO:0006909	215	0.033
regulation of apoptotic process	GO:0042981	130	0.033
response to organic cyclic compound	GO:0014070	89	0.033
mapk cascade	GO:0000165	107	0.032
homeostatic process	GO:0042592	199	0.031
negative regulation of reactive oxygen species metabolic process	GO:2000378	1	0.031
apoptotic process	GO:0006915	159	0.030
regulation of reactive oxygen species metabolic process	GO:2000377	8	0.030
carbohydrate derivative metabolic process	GO:1901135	217	0.030
cellular amino acid metabolic process	GO:0006520	61	0.029
amine metabolic process	GO:0009308	12	0.029
body morphogenesis	GO:0010171	2	0.029
response to decreased oxygen levels	GO:0036293	58	0.029
anion homeostasis	GO:0055081	3	0.028
organic substance catabolic process	GO:1901575	308	0.028
single organism catabolic process	GO:0044712	228	0.028
purine containing compound metabolic process	GO:0072521	155	0.027
sensory perception of light stimulus	GO:0050953	12	0.027
oxoacid metabolic process	GO:0043436	103	0.026
organic acid metabolic process	GO:0006082	103	0.026
carboxylic acid metabolic process	GO:0019752	92	0.026
negative regulation of programmed cell death	GO:0043069	72	0.025
ribonucleoside metabolic process	GO:0009119	127	0.025
aging	GO:0007568	143	0.025
ethanolamine containing compound metabolic process	GO:0042439	4	0.025
response to oxygen levels	GO:0070482	59	0.024
organelle fission	GO:0048285	340	0.024
muscle system process	GO:0003012	21	0.024
tissue death	GO:0016271	102	0.024
behavioral response to starvation	GO:0042595	6	0.024
gland development	GO:0048732	191	0.024
cellular amine metabolic process	GO:0044106	12	0.023
cholesterol homeostasis	GO:0042632	3	0.023
response to hypoxia	GO:0001666	53	0.023
regulation of sequestering of triglyceride	GO:0010889	3	0.023
developmental programmed cell death	GO:0010623	138	0.022
wing disc morphogenesis	GO:0007472	344	0.022
response to hormone	GO:0009725	45	0.022
nuclear division	GO:0000280	332	0.022
regulation of system process	GO:0044057	36	0.021
positive regulation of signal transduction	GO:0009967	223	0.021
regulation of transport	GO:0051049	181	0.020
single organism biosynthetic process	GO:0044711	206	0.020
positive regulation of response to stimulus	GO:0048584	323	0.020
neutral lipid biosynthetic process	GO:0046460	2	0.020
organic substance transport	GO:0071702	257	0.020
aromatic compound catabolic process	GO:0019439	166	0.020
positive regulation of cell communication	GO:0010647	250	0.020
cholesterol transport	GO:0030301	2	0.020
salivary gland histolysis	GO:0035070	88	0.020
salivary gland development	GO:0007431	162	0.020
protein modification process	GO:0036211	438	0.019
cold acclimation	GO:0009631	8	0.019
salivary gland cell autophagic cell death	GO:0035071	83	0.019
regulation of response to stress	GO:0080134	200	0.019
histolysis	GO:0007559	102	0.019
regulation of cellular ketone metabolic process	GO:0010565	3	0.018
monocarboxylic acid transport	GO:0015718	3	0.018
exocrine system development	GO:0035272	162	0.018
cellular protein modification process	GO:0006464	438	0.018
organic cyclic compound catabolic process	GO:1901361	168	0.018
positive regulation of signaling	GO:0023056	243	0.018
purine ribonucleoside metabolic process	GO:0046128	127	0.018
purine nucleoside metabolic process	GO:0042278	127	0.018
organophosphate metabolic process	GO:0019637	195	0.018
lipid metabolic process	GO:0006629	121	0.018
sulfur compound metabolic process	GO:0006790	59	0.018
response to inorganic substance	GO:0010035	44	0.017
regulation of lipid storage	GO:0010883	22	0.017
salivary gland morphogenesis	GO:0007435	145	0.017
neutral lipid catabolic process	GO:0046461	3	0.017
nucleoside metabolic process	GO:0009116	127	0.017
ribonucleoside catabolic process	GO:0042454	112	0.017
heterocycle catabolic process	GO:0046700	166	0.017
autophagic cell death	GO:0048102	83	0.017
nucleobase containing small molecule metabolic process	GO:0055086	174	0.017
response to copper ion	GO:0046688	4	0.017
developmental growth	GO:0048589	280	0.016
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.016
purine containing compound catabolic process	GO:0072523	112	0.016
negative regulation of response to stimulus	GO:0048585	258	0.016
regulation of intracellular signal transduction	GO:1902531	236	0.016
response to endogenous stimulus	GO:0009719	119	0.016
protein complex biogenesis	GO:0070271	201	0.016
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.016
glycosyl compound metabolic process	GO:1901657	127	0.016
acylglycerol catabolic process	GO:0046464	3	0.016
oligosaccharide transport	GO:0015772	2	0.016
meiosis i	GO:0007127	59	0.015
positive regulation of cellular biosynthetic process	GO:0031328	316	0.015
phosphorylation	GO:0016310	294	0.015
cellular nitrogen compound catabolic process	GO:0044270	165	0.015
muscle contraction	GO:0006936	13	0.015
kidney development	GO:0001822	3	0.015
forebrain development	GO:0030900	2	0.015
chromosome organization	GO:0051276	360	0.015
anatomical structure homeostasis	GO:0060249	97	0.015
regulation of cellular amine metabolic process	GO:0033238	3	0.015
jak stat cascade	GO:0007259	49	0.015
regulation of muscle contraction	GO:0006937	5	0.015
nucleoside catabolic process	GO:0009164	112	0.015
regulation of immune response	GO:0050776	118	0.015
camera type eye development	GO:0043010	4	0.015
regulation of protein metabolic process	GO:0051246	256	0.014
mitotic nuclear division	GO:0007067	213	0.014
androgen metabolic process	GO:0008209	1	0.014
regulation of lipid transport	GO:0032368	3	0.014
chromatin modification	GO:0016568	147	0.014
single organism intracellular transport	GO:1902582	207	0.014
glycerolipid catabolic process	GO:0046503	3	0.014
chaeta development	GO:0022416	97	0.014
immune response	GO:0006955	246	0.014
response to lipid	GO:0033993	38	0.014
regulation of molecular function	GO:0065009	217	0.014
organelle assembly	GO:0070925	198	0.014
protein localization	GO:0008104	284	0.014
regulation of cell cycle	GO:0051726	291	0.014
triglyceride biosynthetic process	GO:0019432	2	0.014
organonitrogen compound biosynthetic process	GO:1901566	117	0.014
sterol homeostasis	GO:0055092	4	0.014
positive regulation of biosynthetic process	GO:0009891	316	0.014
actin filament based process	GO:0030029	220	0.014
negative regulation of gene expression	GO:0010629	387	0.014
alditol phosphate metabolic process	GO:0052646	2	0.014
cellular ketone metabolic process	GO:0042180	24	0.013
cell proliferation	GO:0008283	299	0.013
regulation of catabolic process	GO:0009894	170	0.013
pigmentation	GO:0043473	75	0.013
meiotic nuclear division	GO:0007126	151	0.013
negative regulation of biosynthetic process	GO:0009890	277	0.013
autophagy	GO:0006914	108	0.013
regulation of cellular amino acid metabolic process	GO:0006521	0	0.013
defense response to gram negative bacterium	GO:0050829	94	0.013
positive regulation of cell migration	GO:0030335	2	0.013
purine ribonucleoside catabolic process	GO:0046130	112	0.013
positive regulation of cell motility	GO:2000147	3	0.013
connective tissue development	GO:0061448	3	0.013
carbohydrate derivative biosynthetic process	GO:1901137	85	0.013
single organism behavior	GO:0044708	391	0.013
small gtpase mediated signal transduction	GO:0007264	88	0.013
meiotic cell cycle	GO:0051321	171	0.012
response to lipopolysaccharide	GO:0032496	4	0.012
phenol containing compound metabolic process	GO:0018958	57	0.012
carbohydrate derivative catabolic process	GO:1901136	118	0.012
regulation of cellular protein metabolic process	GO:0032268	243	0.012
regulation of catalytic activity	GO:0050790	185	0.012
cell motility	GO:0048870	251	0.012
cellular lipid metabolic process	GO:0044255	83	0.012
glycosyl compound catabolic process	GO:1901658	112	0.012
neuropeptide signaling pathway	GO:0007218	45	0.012
maintenance of location	GO:0051235	73	0.012
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.012
regulation of multicellular organismal development	GO:2000026	414	0.012
dorsal ventral pattern formation	GO:0009953	133	0.012
compound eye development	GO:0048749	307	0.012
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.012
ras protein signal transduction	GO:0007265	88	0.012
positive regulation of lipid storage	GO:0010884	4	0.012
acylglycerol biosynthetic process	GO:0046463	2	0.012
posttranscriptional regulation of gene expression	GO:0010608	145	0.012
phosphatidylethanolamine metabolic process	GO:0046337	1	0.012
response to gamma radiation	GO:0010332	17	0.012
embryonic development via the syncytial blastoderm	GO:0001700	148	0.012
regulation of phosphorus metabolic process	GO:0051174	210	0.012
negative regulation of cellular biosynthetic process	GO:0031327	277	0.012
telencephalon development	GO:0021537	2	0.011
positive regulation of intracellular signal transduction	GO:1902533	116	0.011
positive regulation of molecular function	GO:0044093	136	0.011
nucleobase containing compound catabolic process	GO:0034655	165	0.011
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.011
spindle organization	GO:0007051	253	0.011
response to monosaccharide	GO:0034284	4	0.011
organophosphate catabolic process	GO:0046434	112	0.011
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.011
mesenchymal cell development	GO:0014031	1	0.011
chromatin organization	GO:0006325	207	0.011
phosphatidylcholine metabolic process	GO:0046470	3	0.011
epithelial cell development	GO:0002064	274	0.011
male meiosis	GO:0007140	52	0.011
adult behavior	GO:0030534	137	0.011
response to glucose	GO:0009749	2	0.011
cell migration	GO:0016477	238	0.011
negative regulation of rna metabolic process	GO:0051253	251	0.011
epithelial cell differentiation	GO:0030855	322	0.011
pigment metabolic process involved in developmental pigmentation	GO:0043324	33	0.011
axis specification	GO:0009798	167	0.011
growth	GO:0040007	359	0.011
transcription from rna polymerase ii promoter	GO:0006366	368	0.011
response to hexose	GO:0009746	3	0.011
rhythmic process	GO:0048511	106	0.011
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.011
meiotic cell cycle process	GO:1903046	132	0.011
cellular macromolecule catabolic process	GO:0044265	136	0.011
regulation of anatomical structure morphogenesis	GO:0022603	242	0.011
negative regulation of cell communication	GO:0010648	223	0.011
positive regulation of cellular amine metabolic process	GO:0033240	0	0.011
immune system process	GO:0002376	347	0.011
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.010
regulation of immune system process	GO:0002682	176	0.010
cellular response to biotic stimulus	GO:0071216	4	0.010
nucleoside phosphate metabolic process	GO:0006753	162	0.010
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.010
fertilization	GO:0009566	26	0.010
organic hydroxy compound metabolic process	GO:1901615	83	0.010
developmental maturation	GO:0021700	172	0.010
glycoprotein biosynthetic process	GO:0009101	41	0.010
regulation of organelle organization	GO:0033043	196	0.010
hindbrain development	GO:0030902	2	0.010
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.010
cellular amide metabolic process	GO:0043603	80	0.010
regionalization	GO:0003002	416	0.010
ribose phosphate metabolic process	GO:0019693	145	0.010
detection of stimulus	GO:0051606	156	0.010
cellular macromolecule localization	GO:0070727	220	0.010
taxis	GO:0042330	304	0.010
purine nucleotide metabolic process	GO:0006163	146	0.010
eye development	GO:0001654	323	0.010
endomembrane system organization	GO:0010256	119	0.010

CG15199 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.180
cardiovascular system disease	DOID:1287	0.180
nervous system disease	DOID:863	0.064
musculoskeletal system disease	DOID:17	0.063
sensory system disease	DOID:0050155	0.054
eye and adnexa disease	DOID:1492	0.054
eye disease	DOID:5614	0.047
disease of metabolism	DOID:0014667	0.043
acquired metabolic disease	DOID:0060158	0.035
central nervous system disease	DOID:331	0.029
integumentary system disease	DOID:16	0.020
hair disease	DOID:421	0.020
glucose metabolism disease	DOID:4194	0.019
carbohydrate metabolism disease	DOID:0050013	0.019
inherited metabolic disorder	DOID:655	0.019
diabetes mellitus	DOID:9351	0.018
type 2 diabetes mellitus	DOID:9352	0.017
familial hyperlipidemia	DOID:1168	0.013
lipid metabolism disorder	DOID:3146	0.013
familial combined hyperlipidemia	DOID:13809	0.013
familial lipoprotein lipase deficiency	DOID:14118	0.011
neurodegenerative disease	DOID:1289	0.010
motor neuron disease	DOID:231	0.010

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