IMP: Integrative Multi-species Prediction

Drosophila melanogaster

138 known processes

e(y)2 (Dmel_CG15191)

enhancer of yellow 2

(Aliases: d,e(y)[2],E(y)2,ENY2,Dmel\CG15191,CG15191)

FLYBASE: FBgn0000618
Entrez: 45848
UniProtKB: Q9VYX1

Process Predictions
Disease Predictions

e(y)2 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
transcription from rna polymerase ii promoter	GO:0006366	368	0.272
positive regulation of macromolecule metabolic process	GO:0010604	405	0.182
positive regulation of rna biosynthetic process	GO:1902680	266	0.150
peptidyl lysine modification	GO:0018205	57	0.145
positive regulation of rna metabolic process	GO:0051254	271	0.117
chromosome organization	GO:0051276	360	0.093
positive regulation of gene expression	GO:0010628	290	0.070
lateral inhibition	GO:0046331	206	0.065
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.063
histone modification	GO:0016570	106	0.061
cellular protein modification process	GO:0006464	438	0.059
mrna catabolic process	GO:0006402	33	0.056
protein acylation	GO:0043543	42	0.048
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.046
response to organic substance	GO:0010033	284	0.046
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.045
positive regulation of transcription dna templated	GO:0045893	266	0.043
regulation of multicellular organismal development	GO:2000026	414	0.042
response to oxygen containing compound	GO:1901700	200	0.042
internal protein amino acid acetylation	GO:0006475	38	0.042
chromatin modification	GO:0016568	147	0.039
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.038
regulation of cell cycle	GO:0051726	291	0.036
protein modification process	GO:0036211	438	0.036
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.034
response to abiotic stimulus	GO:0009628	341	0.033
regulation of meiosis	GO:0040020	3	0.033
regulation of protein metabolic process	GO:0051246	256	0.033
establishment of localization in cell	GO:0051649	402	0.031
carboxylic acid metabolic process	GO:0019752	92	0.029
embryo development ending in birth or egg hatching	GO:0009792	152	0.029
rna localization	GO:0006403	115	0.027
positive regulation of biosynthetic process	GO:0009891	316	0.027
nuclear transport	GO:0051169	72	0.027
organic substance catabolic process	GO:1901575	308	0.026
positive regulation of response to stimulus	GO:0048584	323	0.025
histone acetylation	GO:0016573	38	0.024
mrna metabolic process	GO:0016071	124	0.023
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.023
cell proliferation	GO:0008283	299	0.022
peptidyl lysine acetylation	GO:0018394	39	0.021
regulation of cellular protein metabolic process	GO:0032268	243	0.021
catabolic process	GO:0009056	409	0.021
organic acid metabolic process	GO:0006082	103	0.020
gene silencing	GO:0016458	138	0.020
negative regulation of response to stimulus	GO:0048585	258	0.020
cytoplasmic transport	GO:0016482	130	0.020
cellular catabolic process	GO:0044248	372	0.019
chromatin organization	GO:0006325	207	0.019
rna splicing via transesterification reactions with bulged adenosine as nucleophile	GO:0000377	73	0.019
internal peptidyl lysine acetylation	GO:0018393	38	0.019
small molecule metabolic process	GO:0044281	305	0.019
regulation of intracellular signal transduction	GO:1902531	236	0.019
rna splicing	GO:0008380	83	0.018
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.018
cellular response to organic substance	GO:0071310	132	0.018
response to biotic stimulus	GO:0009607	294	0.018
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.018
regulation of organelle organization	GO:0033043	196	0.018
oxoacid metabolic process	GO:0043436	103	0.017
macromolecule catabolic process	GO:0009057	161	0.017
dendrite development	GO:0016358	204	0.017
larval development	GO:0002164	104	0.016
negative regulation of cellular biosynthetic process	GO:0031327	277	0.016
positive regulation of cell communication	GO:0010647	250	0.015
positive regulation of signaling	GO:0023056	243	0.015
regulation of protein modification process	GO:0031399	112	0.015
negative regulation of intrinsic apoptotic signaling pathway	GO:2001243	1	0.014
positive regulation of cellular biosynthetic process	GO:0031328	316	0.014
rna catabolic process	GO:0006401	37	0.014
positive regulation of signal transduction	GO:0009967	223	0.014
regulation of chromatin silencing	GO:0031935	36	0.013
protein acetylation	GO:0006473	39	0.013
intracellular transport	GO:0046907	228	0.013
rna splicing via transesterification reactions	GO:0000375	73	0.013
regulation of cellular catabolic process	GO:0031329	157	0.013
cellular amino acid metabolic process	GO:0006520	61	0.013
positive regulation of viral process	GO:0048524	2	0.013
positive regulation of cellular protein metabolic process	GO:0032270	118	0.012
covalent chromatin modification	GO:0016569	106	0.012
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.012
rna processing	GO:0006396	147	0.012
growth	GO:0040007	359	0.012
muscle organ development	GO:0007517	127	0.012
smoothened signaling pathway	GO:0007224	49	0.011
amine metabolic process	GO:0009308	12	0.011
posttranscriptional regulation of gene expression	GO:0010608	145	0.011
nuclear export	GO:0051168	24	0.011
regulation of cell division	GO:0051302	72	0.011
regulation of cell proliferation	GO:0042127	163	0.011
response to other organism	GO:0051707	293	0.010
cellular macromolecule catabolic process	GO:0044265	136	0.010
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.010
positive regulation of binding	GO:0051099	4	0.010
protein localization	GO:0008104	284	0.010
nucleotide metabolic process	GO:0009117	161	0.010

e(y)2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org

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