IMP: Integrative Multi-species Prediction

Drosophila melanogaster

15 known processes

CG5325 (Dmel_CG5325)

CG5325 gene product from transcript CG5325-RB

(Aliases: Dmel\CG5325,BEST:GH03076)

Entrez: 34630
FLYBASE: FBgn0032407
UniProtKB: Q8IP97

Process Predictions
Disease Predictions

CG5325 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
embryo development ending in birth or egg hatching	GO:0009792	152	0.075
negative regulation of cellular metabolic process	GO:0031324	382	0.075
vesicle mediated transport	GO:0016192	381	0.067
endocytosis	GO:0006897	310	0.065
homeostatic process	GO:0042592	199	0.047
negative regulation of response to stimulus	GO:0048585	258	0.046
organic substance transport	GO:0071702	257	0.046
death	GO:0016265	284	0.045
cellular ketone metabolic process	GO:0042180	24	0.043
programmed cell death	GO:0012501	257	0.042
establishment of localization in cell	GO:0051649	402	0.041
histolysis	GO:0007559	102	0.040
intracellular transport	GO:0046907	228	0.038
body morphogenesis	GO:0010171	2	0.038
anatomical structure homeostasis	GO:0060249	97	0.038
regulation of localization	GO:0032879	275	0.037
single organism intracellular transport	GO:1902582	207	0.036
cell death	GO:0008219	279	0.034
eye development	GO:0001654	323	0.033
regulation of cell death	GO:0010941	173	0.033
protein complex biogenesis	GO:0070271	201	0.033
positive regulation of biosynthetic process	GO:0009891	316	0.031
intracellular signal transduction	GO:0035556	300	0.030
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.029
developmental programmed cell death	GO:0010623	138	0.029
single organism biosynthetic process	GO:0044711	206	0.029
salivary gland development	GO:0007431	162	0.029
epithelial cell differentiation	GO:0030855	322	0.029
gland development	GO:0048732	191	0.028
chromatin organization	GO:0006325	207	0.027
adult behavior	GO:0030534	137	0.027
negative regulation of defense response	GO:0031348	35	0.027
regulation of immune system process	GO:0002682	176	0.026
proteolysis	GO:0006508	192	0.026
phosphorylation	GO:0016310	294	0.026
response to hexose	GO:0009746	3	0.025
regulation of phosphate metabolic process	GO:0019220	210	0.025
phagocytosis	GO:0006909	215	0.025
positive regulation of macromolecule metabolic process	GO:0010604	405	0.024
innate immune response	GO:0045087	144	0.024
regulation of transport	GO:0051049	181	0.024
negative regulation of immune response	GO:0050777	39	0.024
tissue death	GO:0016271	102	0.023
positive regulation of cellular biosynthetic process	GO:0031328	316	0.023
chromosome organization	GO:0051276	360	0.023
salivary gland morphogenesis	GO:0007435	145	0.023
cellular homeostasis	GO:0019725	80	0.022
tissue homeostasis	GO:0001894	36	0.022
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.021
regulation of protein localization	GO:0032880	76	0.021
positive regulation of response to stimulus	GO:0048584	323	0.021
regulation of phosphorus metabolic process	GO:0051174	210	0.021
positive regulation of cell communication	GO:0010647	250	0.021
cellular protein modification process	GO:0006464	438	0.020
regulation of programmed cell death	GO:0043067	152	0.020
positive regulation of signal transduction	GO:0009967	223	0.020
salivary gland cell autophagic cell death	GO:0035071	83	0.020
transcription from rna polymerase ii promoter	GO:0006366	368	0.020
single organism cellular localization	GO:1902580	180	0.020
oxoacid metabolic process	GO:0043436	103	0.020
positive regulation of signaling	GO:0023056	243	0.019
small molecule metabolic process	GO:0044281	305	0.019
response to oxidative stress	GO:0006979	86	0.018
regulation of anatomical structure morphogenesis	GO:0022603	242	0.018
larval development	GO:0002164	104	0.018
negative regulation of gene expression	GO:0010629	387	0.018
macromolecular complex assembly	GO:0065003	256	0.018
autophagic cell death	GO:0048102	83	0.018
negative regulation of cellular biosynthetic process	GO:0031327	277	0.018
regulation of cellular protein metabolic process	GO:0032268	243	0.017
cell proliferation	GO:0008283	299	0.017
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.017
regulation of steroid metabolic process	GO:0019218	2	0.017
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.017
cellular amino acid metabolic process	GO:0006520	61	0.017
negative regulation of cell communication	GO:0010648	223	0.017
organonitrogen compound metabolic process	GO:1901564	318	0.017
response to endogenous stimulus	GO:0009719	119	0.016
regulation of immune response	GO:0050776	118	0.016
chromatin modification	GO:0016568	147	0.016
gland morphogenesis	GO:0022612	145	0.016
regulation of response to stress	GO:0080134	200	0.016
regulation of protein transport	GO:0051223	57	0.016
protein transport	GO:0015031	155	0.015
carbohydrate derivative metabolic process	GO:1901135	217	0.015
cellular catabolic process	GO:0044248	372	0.015
regulation of intracellular transport	GO:0032386	64	0.015
cellular macromolecular complex assembly	GO:0034622	153	0.015
response to organophosphorus	GO:0046683	2	0.015
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.015
cellular amide metabolic process	GO:0043603	80	0.015
regulation of molecular function	GO:0065009	217	0.015
negative regulation of signal transduction	GO:0009968	206	0.015
chemical homeostasis	GO:0048878	92	0.014
regulation of apoptotic process	GO:0042981	130	0.014
single organism behavior	GO:0044708	391	0.014
response to abiotic stimulus	GO:0009628	341	0.014
head development	GO:0060322	135	0.014
response to organic substance	GO:0010033	284	0.014
aging	GO:0007568	143	0.014
regulation of growth	GO:0040008	233	0.014
regulation of cellular amine metabolic process	GO:0033238	3	0.014
regulation of intracellular signal transduction	GO:1902531	236	0.014
cellular response to dna damage stimulus	GO:0006974	223	0.014
regulation of protein metabolic process	GO:0051246	256	0.014
multicellular organismal aging	GO:0010259	140	0.013
organophosphate metabolic process	GO:0019637	195	0.013
membrane organization	GO:0061024	112	0.013
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.013
negative regulation of cell death	GO:0060548	81	0.013
apoptotic process	GO:0006915	159	0.013
cellular response to external stimulus	GO:0071496	66	0.013
nucleoside triphosphate metabolic process	GO:0009141	120	0.013
organic substance catabolic process	GO:1901575	308	0.013
regulation of cell morphogenesis	GO:0022604	163	0.013
secretion	GO:0046903	109	0.013
biological adhesion	GO:0022610	138	0.013
protein complex assembly	GO:0006461	200	0.013
wound healing	GO:0042060	75	0.013
immune effector process	GO:0002252	98	0.012
regulation of catalytic activity	GO:0050790	185	0.012
intracellular protein transport	GO:0006886	104	0.012
positive regulation of intracellular signal transduction	GO:1902533	116	0.012
determination of adult lifespan	GO:0008340	137	0.012
response to oxygen containing compound	GO:1901700	200	0.012
endomembrane system organization	GO:0010256	119	0.012
cellular response to chemical stimulus	GO:0070887	199	0.012
protein modification process	GO:0036211	438	0.012
protein localization	GO:0008104	284	0.012
organonitrogen compound biosynthetic process	GO:1901566	117	0.012
regulation of cellular localization	GO:0060341	136	0.012
regulation of cell shape	GO:0008360	113	0.011
sensory organ morphogenesis	GO:0090596	260	0.011
negative regulation of protein metabolic process	GO:0051248	85	0.011
establishment of protein localization	GO:0045184	163	0.011
negative regulation of programmed cell death	GO:0043069	72	0.011
organic acid metabolic process	GO:0006082	103	0.011
locomotory behavior	GO:0007626	176	0.011
immune system process	GO:0002376	347	0.011
regulation of phosphorylation	GO:0042325	147	0.011
salivary gland histolysis	GO:0035070	88	0.011
response to nitrogen compound	GO:1901698	90	0.011
response to glucose	GO:0009749	2	0.011
carboxylic acid metabolic process	GO:0019752	92	0.011
negative regulation of biosynthetic process	GO:0009890	277	0.011
multicellular organismal homeostasis	GO:0048871	41	0.011
protein phosphorylation	GO:0006468	169	0.011
regulation of innate immune response	GO:0045088	71	0.011
growth	GO:0040007	359	0.011
negative regulation of organelle organization	GO:0010639	56	0.011
regulation of hydrolase activity	GO:0051336	97	0.011
morphogenesis of an epithelium	GO:0002009	276	0.010
respiratory system development	GO:0060541	213	0.010
regionalization	GO:0003002	416	0.010
cellular macromolecule localization	GO:0070727	220	0.010
protein processing	GO:0016485	68	0.010
negative regulation of cellular protein metabolic process	GO:0032269	85	0.010
camera type eye development	GO:0043010	4	0.010

CG5325 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of metabolism	DOID:0014667	0.138
familial visceral amyloidosis	DOID:0050636	0.059
amyloidosis	DOID:9120	0.059
acquired metabolic disease	DOID:0060158	0.059
disease of anatomical entity	DOID:7	0.039
inherited metabolic disorder	DOID:655	0.022
nervous system disease	DOID:863	0.012
disease of cellular proliferation	DOID:14566	0.010

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