IMP: Integrative Multi-species Prediction

Drosophila melanogaster

119 known processes

Taf1 (Dmel_CG17603)

TBP-associated factor 1

(Aliases: CG17603,TAF[[II]]250/230,Taf[[II]]250,Taf230,l(3)84Ab,TAF200,dmTAF[[II]]230,Taf1p,dTAF250,TAF[[II]],TAF[II]250,dTAF[[II]]250,TFIID TAF250,cell,EfW1,TAF,dTAF[[II]]230,TAF250,TAF[[II]]230,SR3-5,dTAF230,TAF[[II]]250,TAF230,TAFII-250,BG:DS00004.13,cel,Taf200,TAF250/230,Dmel\CG17603,d230,dTAFII250,TAF1,dmTAF1,Taf250,TFIID,p230,TAFII250)

Entrez: 40813
FLYBASE: FBgn0010355
UniProtKB: E1JJ72
UniProtKB: P51123

Process Predictions
Disease Predictions

Taf1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
neuron projection guidance	GO:0097485	241	0.940
regulation of mitotic cell cycle	GO:0007346	190	0.939
negative regulation of gene expression	GO:0010629	387	0.924
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.877
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.867
negative regulation of biosynthetic process	GO:0009890	277	0.792
intracellular signal transduction	GO:0035556	300	0.741
regulation of intracellular signal transduction	GO:1902531	236	0.719
negative regulation of cellular metabolic process	GO:0031324	382	0.716
compound eye development	GO:0048749	307	0.696
head development	GO:0060322	135	0.624
axonogenesis	GO:0007409	290	0.621
locomotory behavior	GO:0007626	176	0.570
negative regulation of rna metabolic process	GO:0051253	251	0.530
protein dna complex subunit organization	GO:0071824	86	0.524
axon guidance	GO:0007411	233	0.515
axon development	GO:0061564	297	0.473
macromolecular complex assembly	GO:0065003	256	0.473
positive regulation of rna biosynthetic process	GO:1902680	266	0.469
post embryonic appendage morphogenesis	GO:0035120	385	0.469
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.467
localization of cell	GO:0051674	257	0.448
body morphogenesis	GO:0010171	2	0.440	Worm
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.433
taxis	GO:0042330	304	0.430
central nervous system development	GO:0007417	201	0.418
cell motility	GO:0048870	251	0.415
growth	GO:0040007	359	0.414
anterior posterior pattern specification	GO:0009952	136	0.409
cellular protein localization	GO:0034613	160	0.403
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.397
lateral inhibition	GO:0046331	206	0.394
negative regulation of rna biosynthetic process	GO:1902679	240	0.392
rhythmic process	GO:0048511	106	0.389
regulation of cell cycle	GO:0051726	291	0.387
protein modification process	GO:0036211	438	0.384	Human Mouse
cell migration	GO:0016477	238	0.364
forebrain development	GO:0030900	2	0.360
transcription from rna polymerase ii promoter	GO:0006366	368	0.357
positive regulation of transcription dna templated	GO:0045893	266	0.349
appendage development	GO:0048736	401	0.343
dendrite morphogenesis	GO:0048813	199	0.331
dendrite development	GO:0016358	204	0.327
negative regulation of cellular biosynthetic process	GO:0031327	277	0.325
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.322
cell proliferation	GO:0008283	299	0.317
regulation of growth	GO:0040008	233	0.311
positive regulation of biosynthetic process	GO:0009891	316	0.308
endocytosis	GO:0006897	310	0.302	Worm
organonitrogen compound metabolic process	GO:1901564	318	0.302
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.297
compound eye photoreceptor cell differentiation	GO:0001751	140	0.295
muscle structure development	GO:0061061	224	0.293
positive regulation of macromolecule metabolic process	GO:0010604	405	0.290
nucleoside metabolic process	GO:0009116	127	0.281
cell cycle phase transition	GO:0044770	140	0.280
meiotic cell cycle process	GO:1903046	132	0.279
eye morphogenesis	GO:0048592	260	0.276
multi organism behavior	GO:0051705	175	0.268
regulation of localization	GO:0032879	275	0.264
regulation of cell death	GO:0010941	173	0.264
vesicle mediated transport	GO:0016192	381	0.263	Worm
cellular catabolic process	GO:0044248	372	0.262	Human
phototransduction	GO:0007602	52	0.262
single organism behavior	GO:0044708	391	0.260
imaginal disc derived appendage development	GO:0048737	399	0.258
chromatin organization	GO:0006325	207	0.257	Human Mouse
stem cell maintenance	GO:0019827	67	0.254
cell division	GO:0051301	248	0.254
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.244
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.239
positive regulation of response to stimulus	GO:0048584	323	0.236
purine ribonucleotide metabolic process	GO:0009150	145	0.229
protein complex biogenesis	GO:0070271	201	0.227
developmental growth	GO:0048589	280	0.225
positive regulation of rna metabolic process	GO:0051254	271	0.225
small gtpase mediated signal transduction	GO:0007264	88	0.225
tissue morphogenesis	GO:0048729	297	0.222
eye photoreceptor cell differentiation	GO:0001754	145	0.222
nucleotide metabolic process	GO:0009117	161	0.218
positive regulation of cellular biosynthetic process	GO:0031328	316	0.218
photoreceptor cell differentiation	GO:0046530	170	0.216
male gamete generation	GO:0048232	201	0.214
dna metabolic process	GO:0006259	227	0.213
death	GO:0016265	284	0.205
nuclear division	GO:0000280	332	0.205
eye development	GO:0001654	323	0.203
neuron fate commitment	GO:0048663	50	0.202
neuroblast proliferation	GO:0007405	74	0.195
programmed cell death	GO:0012501	257	0.186
positive regulation of gene expression	GO:0010628	290	0.185
positive regulation of signal transduction	GO:0009967	223	0.185
circulatory system development	GO:0072359	82	0.181
chromosome organization	GO:0051276	360	0.172	Human Mouse
regulation of phosphorylation	GO:0042325	147	0.170
appendage morphogenesis	GO:0035107	397	0.167
histone modification	GO:0016570	106	0.164	Human Mouse
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.161
stem cell development	GO:0048864	79	0.160
cytoskeleton dependent cytokinesis	GO:0061640	81	0.158
regionalization	GO:0003002	416	0.157
compound eye photoreceptor fate commitment	GO:0001752	36	0.155
protein complex assembly	GO:0006461	200	0.154
axis specification	GO:0009798	167	0.153
photoreceptor cell fate commitment	GO:0046552	41	0.152
positive regulation of signaling	GO:0023056	243	0.152
homeostatic process	GO:0042592	199	0.151
epithelial cell differentiation	GO:0030855	322	0.150
meiotic cytokinesis	GO:0033206	33	0.150
positive regulation of cell communication	GO:0010647	250	0.149
ovarian follicle cell development	GO:0030707	248	0.145
purine containing compound catabolic process	GO:0072523	112	0.143
adult behavior	GO:0030534	137	0.143
epithelial cell development	GO:0002064	274	0.143
morphogenesis of an epithelium	GO:0002009	276	0.141
ribonucleoside metabolic process	GO:0009119	127	0.141
regulation of protein metabolic process	GO:0051246	256	0.140	Human
compound eye morphogenesis	GO:0001745	249	0.140
ribose phosphate metabolic process	GO:0019693	145	0.138
gene silencing	GO:0016458	138	0.137
immune system process	GO:0002376	347	0.136
germ line stem cell maintenance	GO:0030718	50	0.133
oocyte differentiation	GO:0009994	145	0.132
regulation of cell proliferation	GO:0042127	163	0.131
wing disc morphogenesis	GO:0007472	344	0.131
apoptotic process	GO:0006915	159	0.129
negative regulation of mitotic cell cycle	GO:0045930	109	0.127
spindle organization	GO:0007051	253	0.126
regulation of developmental growth	GO:0048638	174	0.123
chemotaxis	GO:0006935	249	0.123
protein localization	GO:0008104	284	0.122
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.122
detection of external stimulus	GO:0009581	66	0.119
cellular response to endogenous stimulus	GO:0071495	80	0.117
brain development	GO:0007420	120	0.114
positive regulation of cellular component organization	GO:0051130	156	0.114
digestive system development	GO:0055123	149	0.113
negative regulation of cell differentiation	GO:0045596	143	0.113
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.112
chromatin silencing	GO:0006342	76	0.111
meiotic cell cycle	GO:0051321	171	0.110
cellular macromolecule localization	GO:0070727	220	0.109
cardiovascular system development	GO:0072358	82	0.107
embryonic hemopoiesis	GO:0035162	26	0.106
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.104
organelle assembly	GO:0070925	198	0.101
larval development	GO:0002164	104	0.099	Worm
negative regulation of transcription dna templated	GO:0045892	237	0.099
establishment of localization in cell	GO:0051649	402	0.096
cell death	GO:0008219	279	0.096
regulation of neurogenesis	GO:0050767	158	0.095
negative regulation of signaling	GO:0023057	219	0.094
negative regulation of response to stimulus	GO:0048585	258	0.094
histone deubiquitination	GO:0016578	8	0.093
gland development	GO:0048732	191	0.091
hindbrain development	GO:0030902	2	0.088
positive regulation of growth	GO:0045927	75	0.087
single organism intracellular transport	GO:1902582	207	0.086
regulation of gene silencing	GO:0060968	63	0.083
nucleosome organization	GO:0034728	59	0.083
tube development	GO:0035295	244	0.082
purine ribonucleoside catabolic process	GO:0046130	112	0.082
response to endogenous stimulus	GO:0009719	119	0.080
eye photoreceptor cell fate commitment	GO:0042706	37	0.080
nucleobase containing compound catabolic process	GO:0034655	165	0.080
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.079
positive regulation of cell proliferation	GO:0008284	47	0.079
positive regulation of intracellular signal transduction	GO:1902533	116	0.078
modification dependent macromolecule catabolic process	GO:0043632	79	0.078	Human
organophosphate metabolic process	GO:0019637	195	0.078
single organism catabolic process	GO:0044712	228	0.078
sensory organ morphogenesis	GO:0090596	260	0.078
gonad development	GO:0008406	50	0.075	Worm
regulation of organelle organization	GO:0033043	196	0.075
positive regulation of transport	GO:0051050	92	0.075
stem cell proliferation	GO:0072089	88	0.075
negative regulation of cell cycle	GO:0045786	116	0.073
organic substance transport	GO:0071702	257	0.073
regulation of cell cycle process	GO:0010564	181	0.072
positive regulation of developmental process	GO:0051094	143	0.072
carbohydrate derivative metabolic process	GO:1901135	217	0.071
positive regulation of protein import into nucleus	GO:0042307	21	0.071
regulation of cellular protein metabolic process	GO:0032268	243	0.071	Human
nucleotide catabolic process	GO:0009166	109	0.071
eye antennal disc development	GO:0035214	60	0.071
single organism biosynthetic process	GO:0044711	206	0.070
rna splicing	GO:0008380	83	0.070
regulation of multicellular organismal development	GO:2000026	414	0.070
regulation of cell differentiation	GO:0045595	302	0.070
nucleobase containing small molecule metabolic process	GO:0055086	174	0.069
humoral immune response	GO:0006959	117	0.069
development of primary sexual characteristics	GO:0045137	50	0.068	Worm
protein targeting to nucleus	GO:0044744	51	0.068
imaginal disc derived wing hair organization	GO:0035317	45	0.067
rna transport	GO:0050658	46	0.066
mrna splice site selection	GO:0006376	1	0.066
histone acetylation	GO:0016573	38	0.066	Human Mouse
purine ribonucleoside metabolic process	GO:0046128	127	0.065
dna templated transcriptional preinitiation complex assembly	GO:0070897	20	0.065
eye photoreceptor cell development	GO:0042462	81	0.064
protein localization to organelle	GO:0033365	82	0.063
ras protein signal transduction	GO:0007265	88	0.062
regulation of molecular function	GO:0065009	217	0.062
embryonic hindgut morphogenesis	GO:0048619	48	0.062
histone h2a acetylation	GO:0043968	1	0.061
regulation of neuron differentiation	GO:0045664	103	0.061
nucleoside triphosphate catabolic process	GO:0009143	108	0.060
tube morphogenesis	GO:0035239	191	0.060
positive regulation of multicellular organismal process	GO:0051240	143	0.060
morphogenesis of a polarized epithelium	GO:0001738	93	0.060
digestive tract morphogenesis	GO:0048546	127	0.060
male meiosis cytokinesis	GO:0007112	26	0.060
cellular response to organic substance	GO:0071310	132	0.059
multi organism reproductive behavior	GO:0044705	121	0.059
detection of light stimulus	GO:0009583	58	0.058
ribosomal large subunit biogenesis	GO:0042273	1	0.058
neurological system process	GO:0050877	358	0.056
positive regulation of phosphorus metabolic process	GO:0010562	139	0.056
muscle cell development	GO:0055001	50	0.056
regulation of multicellular organism growth	GO:0040014	40	0.055
cellular protein modification process	GO:0006464	438	0.054	Human Mouse
regulation of protein modification process	GO:0031399	112	0.054
oocyte axis specification	GO:0007309	108	0.053
phagocytosis	GO:0006909	215	0.053
response to abiotic stimulus	GO:0009628	341	0.053
telencephalon development	GO:0021537	2	0.053
regulation of neuron projection development	GO:0010975	69	0.052
single organism cellular localization	GO:1902580	180	0.052
dna templated transcription initiation	GO:0006352	25	0.051
stem cell differentiation	GO:0048863	117	0.051
purine nucleotide metabolic process	GO:0006163	146	0.051
biological adhesion	GO:0022610	138	0.050
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.050
oocyte maturation	GO:0001556	3	0.050
sex differentiation	GO:0007548	81	0.050	Worm
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.050
chromatin assembly or disassembly	GO:0006333	52	0.050
mitotic cell cycle embryonic	GO:0045448	38	0.050
regulation of phosphate metabolic process	GO:0019220	210	0.050
regulation of response to stress	GO:0080134	200	0.049
rna processing	GO:0006396	147	0.049
ion transport	GO:0006811	145	0.049
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.048
positive regulation of protein transport	GO:0051222	37	0.048
anterior posterior axis specification	GO:0009948	109	0.048
muscle cell differentiation	GO:0042692	103	0.047
glycosyl compound metabolic process	GO:1901657	127	0.047
stem cell division	GO:0017145	69	0.046
regulation of mapk cascade	GO:0043408	92	0.045
phosphorylation	GO:0016310	294	0.045	Human
positive regulation of phosphate metabolic process	GO:0045937	139	0.045
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.045
negative regulation of catabolic process	GO:0009895	36	0.044
regulation of phosphorus metabolic process	GO:0051174	210	0.044
spermatogenesis	GO:0007283	200	0.044
imaginal disc derived leg morphogenesis	GO:0007480	80	0.043
mitotic cytokinesis	GO:0000281	50	0.043
actin cytoskeleton organization	GO:0030036	206	0.043
ribonucleotide metabolic process	GO:0009259	145	0.042
mitotic cell cycle phase transition	GO:0044772	138	0.042
protein dna complex assembly	GO:0065004	63	0.042
regulation of epithelial cell proliferation	GO:0050678	4	0.041
catabolic process	GO:0009056	409	0.041	Human
histone h3 acetylation	GO:0043966	11	0.041
cellular amino acid metabolic process	GO:0006520	61	0.040
regulation of programmed cell death	GO:0043067	152	0.040
response to oxygen containing compound	GO:1901700	200	0.040
cuticle development	GO:0042335	86	0.040	Worm
eggshell formation	GO:0030703	105	0.040
peptidyl lysine modification	GO:0018205	57	0.040	Human Mouse
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.039
purine nucleoside catabolic process	GO:0006152	112	0.039
positive regulation of phosphorylation	GO:0042327	87	0.039
digestive tract development	GO:0048565	149	0.038
small molecule metabolic process	GO:0044281	305	0.038
regulation of cell growth	GO:0001558	43	0.038
establishment of ommatidial planar polarity	GO:0042067	49	0.038
circadian rhythm	GO:0007623	105	0.038
meiotic nuclear division	GO:0007126	151	0.038
reproductive structure development	GO:0048608	74	0.038	Worm
cellular macromolecular complex assembly	GO:0034622	153	0.037
chitin based cuticle development	GO:0040003	49	0.037
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.037
protein modification by small protein conjugation or removal	GO:0070647	106	0.037
reproductive behavior	GO:0019098	122	0.036
regulation of apoptotic process	GO:0042981	130	0.036
morphogenesis of embryonic epithelium	GO:0016331	94	0.036
negative regulation of cell communication	GO:0010648	223	0.036
actin filament based process	GO:0030029	220	0.036
embryonic morphogenesis	GO:0048598	206	0.036
protein phosphorylation	GO:0006468	169	0.035	Human
regulation of chromatin organization	GO:1902275	32	0.035
regulation of cellular catabolic process	GO:0031329	157	0.035	Human
purine nucleotide catabolic process	GO:0006195	109	0.035
proteolysis involved in cellular protein catabolic process	GO:0051603	83	0.035	Human
striated muscle cell differentiation	GO:0051146	90	0.035
regulation of cell cycle phase transition	GO:1901987	130	0.034
glycosyl compound catabolic process	GO:1901658	112	0.034
organelle fission	GO:0048285	340	0.034
positive regulation of molecular function	GO:0044093	136	0.034
positive regulation of organelle organization	GO:0010638	65	0.034
regulation of dna templated transcription elongation	GO:0032784	17	0.034
protein import	GO:0017038	55	0.034
glial cell migration	GO:0008347	31	0.033
regulation of ras protein signal transduction	GO:0046578	93	0.033
positive regulation of transcription factor import into nucleus	GO:0042993	19	0.033
mitotic g2 m transition checkpoint	GO:0044818	70	0.033
regulation of alternative mrna splicing via spliceosome	GO:0000381	60	0.032
response to organic substance	GO:0010033	284	0.031
regulation of anatomical structure morphogenesis	GO:0022603	242	0.031
peptidyl amino acid modification	GO:0018193	105	0.031	Human Mouse
nephron development	GO:0072006	3	0.031
inositol lipid mediated signaling	GO:0048017	4	0.031
rna polymerase ii transcriptional preinitiation complex assembly	GO:0051123	20	0.031
regulation of transport	GO:0051049	181	0.031
regulation of embryonic development	GO:0045995	68	0.031
transcription initiation from rna polymerase ii promoter	GO:0006367	25	0.031
asymmetric cell division	GO:0008356	37	0.031
nucleus organization	GO:0006997	45	0.031
germarium derived female germ line cyst formation	GO:0030727	42	0.030
negative regulation of meiotic cell cycle	GO:0051447	2	0.030
oocyte construction	GO:0007308	112	0.030
negative regulation of developmental process	GO:0051093	201	0.030
negative regulation of organelle organization	GO:0010639	56	0.030
neuron recognition	GO:0008038	101	0.029
regulation of erk1 and erk2 cascade	GO:0070372	39	0.029
transcription elongation from rna polymerase ii promoter	GO:0006368	18	0.029
dna templated transcription elongation	GO:0006354	18	0.029
imaginal disc derived wing morphogenesis	GO:0007476	337	0.029
regulation of bmp signaling pathway	GO:0030510	23	0.029
mrna splicing via spliceosome	GO:0000398	73	0.029
regulation of vesicle mediated transport	GO:0060627	59	0.029
female germ line stem cell maintenance	GO:0036099	8	0.029
regulation of locomotion	GO:0040012	42	0.029
cellular component disassembly	GO:0022411	46	0.029
regulation of epithelial cell differentiation	GO:0030856	4	0.029
regulation of chromosome organization	GO:0033044	64	0.029
establishment of protein localization to organelle	GO:0072594	62	0.029
pigmentation	GO:0043473	75	0.028
muscle organ development	GO:0007517	127	0.028
ribonucleoside monophosphate metabolic process	GO:0009161	51	0.028
erk1 and erk2 cascade	GO:0070371	39	0.028
chromatin modification	GO:0016568	147	0.028	Human Mouse
defense response	GO:0006952	300	0.028
purine nucleoside metabolic process	GO:0042278	127	0.028
limb morphogenesis	GO:0035108	1	0.027
positive regulation of cellular amine metabolic process	GO:0033240	0	0.027
nephron tubule morphogenesis	GO:0072078	3	0.027
jak stat cascade	GO:0007259	49	0.027
cystoblast division	GO:0007282	10	0.027
purine ribonucleotide catabolic process	GO:0009154	109	0.027
carbohydrate derivative catabolic process	GO:1901136	118	0.027
protein ubiquitination	GO:0016567	70	0.027
nucleoside phosphate metabolic process	GO:0006753	162	0.027
multicellular organism growth	GO:0035264	46	0.026
positive regulation of neurogenesis	GO:0050769	41	0.026
positive regulation of apoptotic signaling pathway	GO:2001235	4	0.026
mapk cascade	GO:0000165	107	0.026
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.026
embryonic pattern specification	GO:0009880	174	0.026
embryonic development via the syncytial blastoderm	GO:0001700	148	0.026
negative regulation of neuron death	GO:1901215	18	0.026
reproductive system development	GO:0061458	74	0.026	Worm
macromolecule catabolic process	GO:0009057	161	0.026	Human
purine containing compound metabolic process	GO:0072521	155	0.026
central nervous system projection neuron axonogenesis	GO:0021952	6	0.026
regulation of response to external stimulus	GO:0032101	115	0.026
cell growth	GO:0016049	108	0.025
oocyte dorsal ventral axis specification	GO:0007310	34	0.025
macromolecule deacylation	GO:0098732	11	0.025
regulation of cell migration	GO:0030334	22	0.025
axon target recognition	GO:0007412	16	0.025
bmp signaling pathway	GO:0030509	27	0.025
cell maturation	GO:0048469	144	0.025
regulation of neuroblast proliferation	GO:1902692	34	0.025
macromolecular complex disassembly	GO:0032984	37	0.025
mating behavior	GO:0007617	106	0.025
maintenance of protein location	GO:0045185	28	0.025
cellular component assembly involved in morphogenesis	GO:0010927	151	0.025
protein modification by small protein conjugation	GO:0032446	79	0.025
respiratory system development	GO:0060541	213	0.024
regulation of endocytosis	GO:0030100	37	0.024
response to peptide hormone	GO:0043434	29	0.024
ameboidal type cell migration	GO:0001667	151	0.024
limb development	GO:0060173	1	0.024
non sensory hair organization	GO:0035316	47	0.024
rrna processing	GO:0006364	3	0.024
ncrna metabolic process	GO:0034660	43	0.023
positive regulation of protein metabolic process	GO:0051247	128	0.023	Human
open tracheal system development	GO:0007424	204	0.023
connective tissue development	GO:0061448	3	0.023
establishment of protein localization	GO:0045184	163	0.023
positive regulation of erk1 and erk2 cascade	GO:0070374	36	0.023
regulation of meiosis	GO:0040020	3	0.023
protein import into nucleus	GO:0006606	51	0.023
ribonucleoprotein complex biogenesis	GO:0022613	31	0.023
regulation of cellular response to stress	GO:0080135	89	0.022
regulation of behavior	GO:0050795	75	0.022
detection of stimulus	GO:0051606	156	0.022
regulation of protein localization	GO:0032880	76	0.022
regulation of microtubule based process	GO:0032886	49	0.022
negative regulation of cell death	GO:0060548	81	0.022
regulation of anatomical structure size	GO:0090066	163	0.022
detection of abiotic stimulus	GO:0009582	66	0.022
mrna metabolic process	GO:0016071	124	0.022
single organism membrane organization	GO:0044802	93	0.022
negative regulation of neurogenesis	GO:0050768	53	0.022
endoderm formation	GO:0001706	3	0.022
multi multicellular organism process	GO:0044706	123	0.022
kidney epithelium development	GO:0072073	3	0.022
macromolecule methylation	GO:0043414	45	0.022
renal tubule morphogenesis	GO:0061333	44	0.021
mating	GO:0007618	120	0.021
negative regulation of cell proliferation	GO:0008285	69	0.021
dorsal ventral axis specification	GO:0009950	66	0.021
central nervous system neuron differentiation	GO:0021953	8	0.021
positive regulation of mapk cascade	GO:0043410	63	0.021
negative regulation of neuroblast proliferation	GO:0007406	27	0.021
nucleoside monophosphate catabolic process	GO:0009125	39	0.021
positive regulation of nfat protein import into nucleus	GO:0051533	16	0.021
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	65	0.021
positive regulation of catabolic process	GO:0009896	105	0.021	Human
exocrine system development	GO:0035272	162	0.021
response to radiation	GO:0009314	155	0.021
negative regulation of multicellular organismal process	GO:0051241	142	0.021
purine ribonucleoside monophosphate metabolic process	GO:0009167	50	0.020
r7 cell differentiation	GO:0045466	43	0.020
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.020
maintenance of location	GO:0051235	73	0.020
genitalia development	GO:0048806	26	0.020	Worm
positive regulation of cell differentiation	GO:0045597	64	0.020
striated muscle cell development	GO:0055002	50	0.020
cilium morphogenesis	GO:0060271	39	0.020
columnar cuboidal epithelial cell development	GO:0002066	249	0.020
centrosome organization	GO:0051297	163	0.020
single organism nuclear import	GO:1902593	51	0.020
regulation of protein modification by small protein conjugation or removal	GO:1903320	25	0.020
segmentation	GO:0035282	207	0.019
female germ line cyst formation	GO:0048135	42	0.019
germarium derived egg chamber formation	GO:0007293	101	0.019
cellular response to oxygen containing compound	GO:1901701	79	0.019
ubiquitin dependent protein catabolic process	GO:0006511	78	0.019	Human
regulation of cellular localization	GO:0060341	136	0.019
positive regulation of cell death	GO:0010942	69	0.019
mitotic cell cycle checkpoint	GO:0007093	88	0.019
regulation of sequestering of calcium ion	GO:0051282	3	0.019
atp metabolic process	GO:0046034	49	0.019
nuclear import	GO:0051170	51	0.019
endodermal cell differentiation	GO:0035987	3	0.019
protein catabolic process	GO:0030163	101	0.019	Human
cellular response to organonitrogen compound	GO:0071417	36	0.019
response to other organism	GO:0051707	293	0.019
mesoderm development	GO:0007498	78	0.019
organophosphate catabolic process	GO:0046434	112	0.019
regulation of nucleotide metabolic process	GO:0006140	62	0.019
microtubule organizing center organization	GO:0031023	168	0.018
chromosome segregation	GO:0007059	157	0.018
developmental programmed cell death	GO:0010623	138	0.018
positive regulation of nucleocytoplasmic transport	GO:0046824	24	0.018
protein complex disassembly	GO:0043241	36	0.018
establishment or maintenance of cell polarity	GO:0007163	167	0.018
carboxylic acid metabolic process	GO:0019752	92	0.018
developmental pigmentation	GO:0048066	68	0.018
neuron projection extension	GO:1990138	32	0.018
organonitrogen compound catabolic process	GO:1901565	128	0.018
meiosis i	GO:0007127	59	0.018
chromatin assembly	GO:0031497	48	0.018
camera type eye development	GO:0043010	4	0.018
regulation of wnt signaling pathway	GO:0030111	68	0.018
response to oxidative stress	GO:0006979	86	0.017
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	38	0.017
chaeta morphogenesis	GO:0008407	42	0.017
cation transport	GO:0006812	110	0.017
regulation of gene expression epigenetic	GO:0040029	128	0.017
regulation of dendrite development	GO:0050773	37	0.017
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.017
nephron tubule development	GO:0072080	3	0.017
notch signaling pathway	GO:0007219	120	0.017
regulation of mrna processing	GO:0050684	71	0.017
cellular response to hormone stimulus	GO:0032870	44	0.017
cell aging	GO:0007569	2	0.017
cellular protein catabolic process	GO:0044257	83	0.017	Human
oocyte development	GO:0048599	124	0.017
establishment of rna localization	GO:0051236	47	0.017
nucleobase containing compound transport	GO:0015931	56	0.017

Taf1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.086
muscular disease	DOID:0080000	0.061
musculoskeletal system disease	DOID:17	0.061
muscle tissue disease	DOID:66	0.061
myopathy	DOID:423	0.061
nonsyndromic deafness	DOID:0050563	0.030
nervous system disease	DOID:863	0.030
auditory system disease	DOID:2742	0.030
autosomal dominant nonsyndromic deafness	DOID:0050564	0.030
sensory system disease	DOID:0050155	0.030
disease of cellular proliferation	DOID:14566	0.026
cancer	DOID:162	0.020
organ system cancer	DOID:0050686	0.019

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