Drosophila melanogaster

78 known processes

ph-d (Dmel_CG3895)

polyhomeotic distal

(Aliases: PhD,ph,phm,EG:BACN25G24.3,ph[d],Dmel\CG3895,DROZFP,PH-d,CG3895,ph-D,phd,PH,PHD,Ph,ph[D])

ph-d biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
neuron projection guidanceGO:00974852410.786
chromatin modificationGO:00165681470.692
Human
positive regulation of rna biosynthetic processGO:19026802660.675
positive regulation of gene expressionGO:00106282900.655
imaginal disc derived wing morphogenesisGO:00074763370.651
gene silencingGO:00164581380.533
Fly
cell cycle comprising mitosis without cytokinesisGO:0033301250.524
developmental pigmentationGO:0048066680.505
negative regulation of macromolecule biosynthetic processGO:00105582700.459
positive regulation of transcription dna templatedGO:00458932660.444
chromosome condensationGO:0030261410.437
negative regulation of rna metabolic processGO:00512532510.434
histone modificationGO:00165701060.426
Human
regionalizationGO:00030024160.359
peptidyl lysine modificationGO:0018205570.325
positive regulation of macromolecule biosynthetic processGO:00105572830.299
dna packagingGO:0006323910.296
chromatin remodelingGO:0006338720.293
pigmentationGO:0043473750.288
positive regulation of nucleic acid templated transcriptionGO:19035082660.284
locomotory behaviorGO:00076261760.275
positive regulation of nitrogen compound metabolic processGO:00511733540.262
chromatin mediated maintenance of transcriptionGO:004809670.249
histone h3 k4 methylationGO:0051568160.234
histone acetylationGO:0016573380.222
dna metabolic processGO:00062592270.222
positive regulation of cellular biosynthetic processGO:00313283160.215
chromatin organizationGO:00063252070.213
Human
regulation of gene silencingGO:0060968630.198
spermatogenesisGO:00072832000.197
Mouse
regulation of gene expression epigeneticGO:00400291280.191
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.189
covalent chromatin modificationGO:00165691060.175
Human
positive regulation of macromolecule metabolic processGO:00106044050.173
positive regulation of rna metabolic processGO:00512542710.167
chromosome organizationGO:00512763600.166
Human
dorsal ventral pattern formationGO:00099531330.165
negative regulation of nucleobase containing compound metabolic processGO:00459342610.160
response to oxygen containing compoundGO:19017002000.153
Mouse Fly
negative regulation of biosynthetic processGO:00098902770.152
appendage morphogenesisGO:00351073970.151
blastoderm segmentationGO:00073501590.149
positive regulation of biosynthetic processGO:00098913160.149
germarium derived female germ line cyst encapsulationGO:003070880.144
Fly
nucleosome positioningGO:001658430.138
negative regulation of rna biosynthetic processGO:19026792400.133
columnar cuboidal epithelial cell differentiationGO:00020652560.133
Fly
histone lysine methylationGO:0034968320.129
cell motilityGO:00488702510.126
transcription from rna polymerase ii promoterGO:00063663680.124
negative regulation of gene expression epigeneticGO:0045814770.118
negative regulation of transcription dna templatedGO:00458922370.115
mitotic cell cycle embryonicGO:0045448380.115
methylationGO:0032259470.112
protein alkylationGO:0008213430.105
sensory organ morphogenesisGO:00905962600.104
segment specificationGO:0007379330.102
regulation of chromatin silencingGO:0031935360.101
wing disc morphogenesisGO:00074723440.100
taxisGO:00423303040.098
pigment metabolic process involved in developmental pigmentationGO:0043324330.097
anterior posterior pattern specificationGO:00099521360.096
negative regulation of cellular biosynthetic processGO:00313272770.094
chitin based cuticle sclerotizationGO:0007593190.093
segmentationGO:00352822070.092
segment polarity determinationGO:0007367250.092
positive regulation of peptidase activityGO:0010952290.086
compound eye pigmentationGO:0048072170.086
dna endoreduplicationGO:0042023220.085
cellular protein modification processGO:00064644380.081
Human
internal protein amino acid acetylationGO:0006475380.079
ovarian follicle cell stalk formationGO:0030713170.076
Fly
telencephalon developmentGO:002153720.075
positive regulation of nucleobase containing compound metabolic processGO:00459353320.075
negative regulation of signal transductionGO:00099682060.075
female genitalia developmentGO:003054060.074
response to other organismGO:00517072930.073
protein modification processGO:00362114380.072
Human
imaginal disc derived appendage morphogenesisGO:00351143950.070
single organism biosynthetic processGO:00447112060.069
determination of genital disc primordiumGO:0035225100.068
positive regulation of gene expression epigeneticGO:0045815160.068
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.067
neurological system processGO:00508773580.065
chromatin silencingGO:0006342760.064
eye pigmentationGO:0048069430.063
hindbrain developmentGO:003090220.062
regulation of cell cycleGO:00517262910.062
histone methylationGO:0016571400.061
negative regulation of gene expressionGO:00106293870.060
response to ecdysoneGO:0035075340.060
Fly
negative regulation of cell communicationGO:00106482230.059
negative regulation of nitrogen compound metabolic processGO:00511722650.058
post embryonic appendage morphogenesisGO:00351203850.056
cell cycle dna replicationGO:0044786230.056
pigment biosynthetic processGO:0046148360.056
compound eye photoreceptor cell differentiationGO:00017511400.056
histone h4 k12 acetylationGO:004398320.054
regulation of protein metabolic processGO:00512462560.054
regulation of response to external stimulusGO:00321011150.053
adult chitin containing cuticle pigmentationGO:0048085160.053
forebrain developmentGO:003090020.053
negative regulation of cell cycleGO:00457861160.053
imaginal disc derived female genitalia developmentGO:000748660.052
nucleoside triphosphate metabolic processGO:00091411200.052
purine ribonucleoside metabolic processGO:00461281270.052
humoral immune responseGO:00069591170.049
protein modification by small protein conjugation or removalGO:00706471060.049
Human
photoreceptor cell developmentGO:0042461960.049
developmental programmed cell deathGO:00106231380.048
single organism behaviorGO:00447083910.048
male gamete generationGO:00482322010.047
Mouse
adult behaviorGO:00305341370.046
nucleoside triphosphate catabolic processGO:00091431080.045
r7 cell differentiationGO:0045466430.044
internal peptidyl lysine acetylationGO:0018393380.044
chromosome segregationGO:00070591570.043
appendage developmentGO:00487364010.043
imaginal disc derived wing vein morphogenesisGO:0008586440.043
nucleoside catabolic processGO:00091641120.043
response to reactive oxygen speciesGO:0000302240.042
regulation of organelle organizationGO:00330431960.042
tissue migrationGO:00901301550.042
response to organic cyclic compoundGO:0014070890.042
Fly
cellular response to dna damage stimulusGO:00069742230.041
double strand break repairGO:0006302260.041
cellular amine metabolic processGO:0044106120.041
regulation of catalytic activityGO:00507901850.040
germ line stem cell maintenanceGO:0030718500.039
positive regulation of molecular functionGO:00440931360.039
gene silencing by rnaGO:0031047570.039
regulation of stem cell proliferationGO:0072091400.039
vesicle mediated transportGO:00161923810.039
male courtship behavior veined wing generated song productionGO:0045433200.038
periodic partitioningGO:0007365290.038
axis specificationGO:00097981670.038
photoreceptor cell differentiationGO:00465301700.038
cellular response to hexose stimulusGO:007133110.038
r3 r4 cell differentiationGO:0048056120.038
response to sterolGO:0036314340.037
Fly
regulation of chromosome organizationGO:0033044640.037
tripartite regional subdivisionGO:00073511030.037
purine ribonucleoside triphosphate metabolic processGO:00092051190.036
nuclear divisionGO:00002803320.036
response to abiotic stimulusGO:00096283410.036
regulation of rna splicingGO:0043484690.036
cellular response to organic substanceGO:00713101320.036
Mouse
syncytial blastoderm mitotic cell cycleGO:0035186210.035
negative regulation of cell cycle processGO:00109481090.035
positive regulation of protein metabolic processGO:00512471280.034
response to hexoseGO:000974630.034
establishment of protein localizationGO:00451841630.034
sister chromatid segregationGO:0000819920.034
ribonucleoside metabolic processGO:00091191270.034
cell recognitionGO:00080371020.033
glycosyl compound metabolic processGO:19016571270.033
ribonucleoside triphosphate catabolic processGO:00092031080.033
amine metabolic processGO:0009308120.032
localization of cellGO:00516742570.032
torso signaling pathwayGO:0008293210.032
heart developmentGO:0007507820.032
organophosphate metabolic processGO:00196371950.032
regulation of chromatin organizationGO:1902275320.032
cuticle pigmentationGO:0048067220.032
meiotic cell cycleGO:00513211710.032
response to biotic stimulusGO:00096072940.032
small molecule metabolic processGO:00442813050.031
positive regulation of catalytic activityGO:00430851180.031
ribose phosphate metabolic processGO:00196931450.031
secondary metabolic processGO:0019748750.031
purine ribonucleoside triphosphate catabolic processGO:00092071080.031
response to external biotic stimulusGO:00432072930.031
rna splicingGO:0008380830.031
nucleoside phosphate catabolic processGO:19012921100.031
glycosyl compound catabolic processGO:19016581120.030
purine nucleoside catabolic processGO:00061521120.030
regulation of cell cycle processGO:00105641810.030
ommochrome metabolic processGO:0046152190.030
chemotaxisGO:00069352490.030
dna replicationGO:0006260480.030
regulation of intracellular signal transductionGO:19025312360.030
limb morphogenesisGO:003510810.030
peptidyl lysine acetylationGO:0018394390.030
dna conformation changeGO:00711031050.029
mesenchymal cell developmentGO:001403110.029
cellular catabolic processGO:00442483720.029
dendrite morphogenesisGO:00488131990.029
organonitrogen compound metabolic processGO:19015643180.029
protein acetylationGO:0006473390.029
response to alcoholGO:0097305950.029
Fly
regulation of chromatin modificationGO:1903308280.029
camera type eye morphogenesisGO:004859320.029
organonitrogen compound biosynthetic processGO:19015661170.029
ribonucleoside triphosphate metabolic processGO:00091991190.029
negative regulation of response to stimulusGO:00485852580.029
male courtship behavior veined wing extensionGO:0048065220.028
protein acylationGO:0043543420.028
histone h4 acetylationGO:0043967130.028
limb developmentGO:006017310.028
camera type eye developmentGO:004301040.028
defense response to other organismGO:00985422250.028
embryonic pattern specificationGO:00098801740.028
phagocytosisGO:00069092150.028
macromolecule methylationGO:0043414450.027
regulation of protein modification processGO:00313991120.027
respiratory system developmentGO:00605412130.027
spinal cord developmentGO:002151010.027
modification dependent protein catabolic processGO:0019941780.027
imaginal disc derived wing vein specificationGO:0007474480.027
negative regulation of heart induction by canonical wnt signaling pathwayGO:000313630.027
embryonic axis specificationGO:00005781070.026
organic substance catabolic processGO:19015753080.026
developmental inductionGO:003112830.026
dendrite developmentGO:00163582040.026
endocytosisGO:00068973100.026
histone h4 k16 acetylationGO:004398440.026
cellular amino acid metabolic processGO:0006520610.026
mitotic sister chromatid segregationGO:0000070870.026
regulation of developmental pigmentationGO:0048070240.026
purine nucleotide catabolic processGO:00061951090.026
nucleus localizationGO:0051647340.026
proteolysisGO:00065081920.025
carbohydrate derivative metabolic processGO:19011352170.025
negative regulation of organelle organizationGO:0010639560.025
gravitaxisGO:0042332260.025
embryonic development via the syncytial blastodermGO:00017001480.025
renal system developmentGO:0072001720.025
epithelial cell migrationGO:00106311480.025
nitrogen compound transportGO:0071705850.025
cuticle pattern formationGO:0035017270.024
meiotic g2 mi transitionGO:000831530.024
purine nucleoside triphosphate catabolic processGO:00091461080.024
response to monosaccharideGO:003428440.024
regulation of localizationGO:00328792750.024
ocellus pigmentationGO:0033060190.024
regulation of microtubule cytoskeleton organizationGO:0070507410.024
germ line cyst encapsulationGO:004813880.024
Fly
response to inorganic substanceGO:0010035440.024
molting cycle chitin based cuticleGO:0007591560.023
negative regulation of epithelial cell proliferationGO:005068040.023
eye photoreceptor cell differentiationGO:00017541450.023
meiotic chromosome condensationGO:001003230.023
dna dependent dna replicationGO:0006261170.023
organic substance transportGO:00717022570.023
organonitrogen compound catabolic processGO:19015651280.023
wnt signaling pathwayGO:0016055980.023
rna processingGO:00063961470.023
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377730.023
regulation of cellular ketone metabolic processGO:001056530.022
nucleoside monophosphate catabolic processGO:0009125390.022
purine nucleoside triphosphate metabolic processGO:00091441190.022
regulation of phosphate metabolic processGO:00192202100.022
protein transportGO:00150311550.022
cardiovascular system developmentGO:0072358820.022
phosphorylationGO:00163102940.022
ribonucleoside catabolic processGO:00424541120.022
regulation of dna metabolic processGO:0051052340.022
pigment metabolic process involved in pigmentationGO:0043474330.022
purine ribonucleoside monophosphate catabolic processGO:0009169380.021
spiracle morphogenesis open tracheal systemGO:0035277220.021
nucleoside phosphate metabolic processGO:00067531620.021
negative regulation of cell differentiationGO:00455961430.021
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.021
posttranscriptional gene silencing by rnaGO:0035194450.021
regulation of phosphorus metabolic processGO:00511742100.021
deathGO:00162652840.021
brain developmentGO:00074201200.021
regulation of molecular functionGO:00650092170.021
ribonucleotide catabolic processGO:00092611090.020
cell fate specificationGO:0001708710.020
molting cycleGO:0042303560.020
regulation of cell morphogenesisGO:00226041630.020
antimicrobial humoral responseGO:0019730990.020
purine nucleoside metabolic processGO:00422781270.020
peptide transportGO:0015833100.020
axon guidanceGO:00074112330.020
dna templated transcription elongationGO:0006354180.020
intracellular signal transductionGO:00355563000.020
adult locomotory behaviorGO:0008344760.020
organophosphate catabolic processGO:00464341120.020
multicellular organismal reproductive behaviorGO:00330571100.020
negative regulation of immune system processGO:0002683500.020
protein ubiquitinationGO:0016567700.020
Human
specification of segmental identity trunkGO:003529270.019
tissue deathGO:00162711020.019
secondary metabolite biosynthetic processGO:0044550240.019
immune system developmentGO:0002520570.019
eye developmentGO:00016543230.019
purine ribonucleotide metabolic processGO:00091501450.019
meiotic nuclear divisionGO:00071261510.019
cell divisionGO:00513012480.019
regulation of cell deathGO:00109411730.018
endodermal cell differentiationGO:003598730.018
proximal distal pattern formationGO:0009954150.018
histolysisGO:00075591020.018
purine containing compound catabolic processGO:00725231120.018
regulation of mrna processingGO:0050684710.018
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.018
morphogenesis of a branching epitheliumGO:0061138450.018
response to glucoseGO:000974920.018
neuron fate commitmentGO:0048663500.018
response to endogenous stimulusGO:00097191190.018
renal tubule morphogenesisGO:0061333440.018
dna methylationGO:000630640.018
positive regulation of phosphate metabolic processGO:00459371390.018
neuroblast fate specificationGO:001401820.018
cell cycle checkpointGO:0000075950.018
apoptotic process involved in morphogenesisGO:006056130.018
regulation of cell shapeGO:00083601130.018
ocellus pigment metabolic processGO:0046158190.017
regulation of multi organism processGO:00439001310.017
body morphogenesisGO:001017120.017
morphogenesis of an epitheliumGO:00020092760.017
Fly
organelle fissionGO:00482853400.017
regulation of protein acetylationGO:190198370.017
purine nucleotide metabolic processGO:00061631460.017
macromolecular complex assemblyGO:00650032560.017
proteolysis involved in cellular protein catabolic processGO:0051603830.017
positive regulation of cysteine type endopeptidase activityGO:2001056240.017
nucleoside metabolic processGO:00091161270.017
axon developmentGO:00615642970.017
branching morphogenesis of an epithelial tubeGO:0048754450.017
molting cycle processGO:0022404290.017
positive regulation of wnt signaling pathwayGO:0030177250.016
regulation of dna templated transcription elongationGO:0032784170.016
negative regulation of heart inductionGO:190132030.016
regulation of r7 cell differentiationGO:0045676150.016
protein modification by small protein removalGO:0070646280.016
regulation of transferase activityGO:0051338580.016
embryonic morphogenesisGO:00485982060.016
protein methylationGO:0006479430.016
eye pigment biosynthetic processGO:0006726320.016
negative regulation of cell deathGO:0060548810.016
male courtship behavior veined wing vibrationGO:0016545210.016
embryonic hemopoiesisGO:0035162260.015
eye pigment metabolic processGO:0042441330.015
regulation of imaginal disc derived wing sizeGO:0044719200.015
tissue morphogenesisGO:00487292970.015
Fly
positive regulation of transferase activityGO:0051347260.015
ubiquitin dependent protein catabolic processGO:0006511780.015
stem cell fate specificationGO:004886620.015
signal releaseGO:0023061490.015
negative regulation of catalytic activityGO:0043086420.015
retina development in camera type eyeGO:006004140.015
rhythmic processGO:00485111060.015
imaginal disc derived appendage developmentGO:00487373990.015
response to ketoneGO:1901654340.015
Fly
heterocycle catabolic processGO:00467001660.015
anterior posterior axis specificationGO:00099481090.014
genital disc pattern formationGO:003522180.014
dna methylation or demethylationGO:004472840.014
defense responseGO:00069523000.014
negative regulation of nucleic acid templated transcriptionGO:19035072400.014
guanosine containing compound metabolic processGO:1901068740.014
positive regulation of stem cell differentiationGO:200073830.014
negative regulation of sequence specific dna binding transcription factor activityGO:004343340.014
protein modification by small protein conjugationGO:0032446790.014
Human
regulation of endopeptidase activityGO:0052548360.014
carboxylic acid metabolic processGO:0019752920.014
spindle organizationGO:00070512530.014
positive regulation of compound eye retinal cell programmed cell deathGO:004667290.014
positive regulation of signalingGO:00230562430.014
compound eye photoreceptor developmentGO:0042051780.014
protein processingGO:0016485680.013
long term memoryGO:0007616620.013
regulation of cellular amide metabolic processGO:0034248390.013
locomotor rhythmGO:0045475560.013
secretionGO:00469031090.013
regulation of embryonic cell shapeGO:0016476300.013
regulation of phosphorylationGO:00423251470.013
erbb signaling pathwayGO:0038127580.013
compound eye developmentGO:00487493070.013
cuticle developmentGO:0042335860.013
regulation of dendrite morphogenesisGO:0048814280.013
morphogenesis of follicular epitheliumGO:0016333360.013
Fly
cellular ketone metabolic processGO:0042180240.013
neural precursor cell proliferationGO:0061351750.013
trachea developmentGO:0060438290.013
memoryGO:0007613940.013
histone h3 k27 methylationGO:007073460.013
single organism carbohydrate metabolic processGO:0044723720.013
establishment of localization in cellGO:00516494020.013
aromatic compound catabolic processGO:00194391660.013
regulation of transcription by chromatin organizationGO:003440130.013
ecdysone mediated induction of salivary gland cell autophagic cell deathGO:0035072120.012
trunk segmentationGO:003529080.012
regulation of histone h3 k4 methylationGO:005156910.012
ribonucleotide metabolic processGO:00092591450.012
spinal cord dorsal ventral patterningGO:002151310.012
anion transportGO:0006820410.012
hemopoiesisGO:0030097460.012
clypeo labral disc developmentGO:003521370.012
axonogenesisGO:00074092900.012
cell agingGO:000756920.012
regulation of nuclear divisionGO:0051783580.012
organic cyclic compound catabolic processGO:19013611680.012
endodermal cell fate commitmentGO:000171130.012
regulation of tube architecture open tracheal systemGO:0035152680.012
activation of innate immune responseGO:000221840.012
apoptotic processGO:00069151590.012
regulation of cellular amino acid metabolic processGO:000652100.012
regulation of cardioblast differentiationGO:005189090.012
regulation of protein transportGO:0051223570.012
regulation of heart morphogenesisGO:200082630.012
epithelium migrationGO:00901321480.012
regulation of catabolic processGO:00098941700.012
positive regulation of phosphorus metabolic processGO:00105621390.012
eye photoreceptor cell fate commitmentGO:0042706370.012
positive regulation of proteolysisGO:0045862520.012
neuroblast fate commitmentGO:0014017190.011
cellular protein catabolic processGO:0044257830.011
negative regulation of cellular component organizationGO:00511291080.011
leg disc morphogenesisGO:0007478800.011
regulation of purine nucleotide metabolic processGO:1900542620.011
negative regulation of apoptotic processGO:0043066630.011
small gtpase mediated signal transductionGO:0007264880.011
signal transduction by phosphorylationGO:00230141070.011
purine ribonucleoside catabolic processGO:00461301120.011
multi multicellular organism processGO:00447061230.011
chemosensory behaviorGO:00076351060.011
male meiosis chromosome segregationGO:0007060100.011
positive regulation of hydrolase activityGO:0051345780.011
courtship behaviorGO:0007619680.011
eye photoreceptor cell developmentGO:0042462810.011
carbohydrate derivative catabolic processGO:19011361180.011
dna alkylationGO:000630540.011
organic anion transportGO:0015711280.011
regulation of eye pigmentationGO:004807370.011
positive regulation of cellular catabolic processGO:0031331950.011
response to organophosphorusGO:004668320.011
cellular response to ketoneGO:1901655170.011
hematopoietic progenitor cell differentiationGO:000224410.011
regulation of proteasomal protein catabolic processGO:0061136390.011
purine ribonucleotide catabolic processGO:00091541090.011
response to gravityGO:0009629260.011
developmental maturationGO:00217001720.011
male courtship behaviorGO:0008049630.011
jak stat cascadeGO:0007259490.011
regulation of immune system processGO:00026821760.011
mitotic nuclear divisionGO:00070672130.011
protein maturationGO:0051604710.011
nucleobase containing small molecule metabolic processGO:00550861740.011
regulation of transcription elongation from rna polymerase ii promoterGO:0034243150.011
dosage compensationGO:0007549160.010
cell deathGO:00082192790.010
immune system processGO:00023763470.010
circulatory system developmentGO:0072359820.010
ras protein signal transductionGO:0007265880.010
signal transduction downstream of smoothenedGO:000722750.010
single organism intracellular transportGO:19025822070.010
smoothened signaling pathwayGO:0007224490.010
regulation of mrna splicing via spliceosomeGO:0048024640.010
regulation of cyclin dependent protein serine threonine kinase activityGO:000007930.010
ommochrome biosynthetic processGO:0006727190.010
stem cell maintenanceGO:0019827670.010
neuron fate determinationGO:004866410.010

ph-d disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
organ system cancerDOID:005068600.019
disease of cellular proliferationDOID:1456600.019
cancerDOID:16200.019