Drosophila melanogaster

151 known processes

Xpd (Dmel_CG9433)

Xeroderma pigmentosum D

(Aliases: DmXPD,XPD/ERCC2,DhXPD,CG9433,ERCC2,DhR3,XPD,l(2)SH2 2137,xpd,Dmel\CG9433,l(2)SH2137)

Xpd biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cell cycle phase transitionGO:00447701400.171
regulation of cell differentiationGO:00455953020.139
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.132
compound eye developmentGO:00487493070.128
cell cycle comprising mitosis without cytokinesisGO:0033301250.127
mitotic cell cycle phase transitionGO:00447721380.114
eye developmentGO:00016543230.114
cell maturationGO:00484691440.111
sensory organ morphogenesisGO:00905962600.097
negative regulation of cell cycle phase transitionGO:19019881030.097
cellular response to dna damage stimulusGO:00069742230.092
mitotic nuclear divisionGO:00070672130.092
compound eye morphogenesisGO:00017452490.092
establishment of localization in cellGO:00516494020.091
negative regulation of gene expressionGO:00106293870.089
oocyte developmentGO:00485991240.085
pronuclear migrationGO:003504640.082
oocyte maturationGO:000155630.077
response to abiotic stimulusGO:00096283410.075
body morphogenesisGO:001017120.073
negative regulation of mitotic cell cycle phase transitionGO:19019911030.072
positive regulation of nucleobase containing compound metabolic processGO:00459353320.066
mitotic dna integrity checkpointGO:0044774750.065
gene silencingGO:00164581380.065
immune system processGO:00023763470.064
negative regulation of cellular metabolic processGO:00313243820.063
sister chromatid segregationGO:0000819920.062
mitotic sister chromatid segregationGO:0000070870.061
organelle localizationGO:00516401480.060
nucleus localizationGO:0051647340.058
positive regulation of cellular biosynthetic processGO:00313283160.058
phosphorylationGO:00163102940.057
establishment or maintenance of apical basal cell polarityGO:0035088340.057
mitotic g2 m transition checkpointGO:0044818700.054
anterior posterior axis specificationGO:00099481090.054
appendage morphogenesisGO:00351073970.054
nuclear migrationGO:0007097200.054
mitotic cell cycle embryonicGO:0045448380.053
negative regulation of mitotic cell cycleGO:00459301090.053
developmental maturationGO:00217001720.052
establishment of organelle localizationGO:00516561220.052
positive regulation of rna biosynthetic processGO:19026802660.051
imaginal disc derived appendage developmentGO:00487373990.049
anterior posterior pattern specificationGO:00099521360.049
epithelial cell developmentGO:00020642740.049
regionalizationGO:00030024160.048
cellular catabolic processGO:00442483720.046
cell cycle checkpointGO:0000075950.046
positive regulation of rna metabolic processGO:00512542710.045
establishment of nucleus localizationGO:0040023260.045
single organism cellular localizationGO:19025801800.045
organelle fusionGO:0048284460.045
mitotic cell cycle checkpointGO:0007093880.044
regulation of localizationGO:00328792750.044
chromosome segregationGO:00070591570.043
cellular protein modification processGO:00064644380.043
rna localizationGO:00064031150.043
regulation of intracellular signal transductionGO:19025312360.042
positive regulation of nucleic acid templated transcriptionGO:19035082660.042
organelle fissionGO:00482853400.042
nucleus organizationGO:0006997450.041
protein modification processGO:00362114380.041
regulation of mitotic cell cycleGO:00073461900.041
organelle assemblyGO:00709251980.041
mrna processingGO:00063971040.041
positive regulation of biosynthetic processGO:00098913160.040
oocyte axis specificationGO:00073091080.040
centrosome organizationGO:00512971630.039
vesicle mediated transportGO:00161923810.039
cell proliferationGO:00082832990.039
humoral immune responseGO:00069591170.039
single fertilizationGO:0007338240.038
deathGO:00162652840.038
cell divisionGO:00513012480.038
embryo development ending in birth or egg hatchingGO:00097921520.037
chromosome organizationGO:00512763600.037
regulation of cyclin dependent protein serine threonine kinase activityGO:000007930.037
positive regulation of macromolecule biosynthetic processGO:00105572830.037
transcription from rna polymerase ii promoterGO:00063663680.037
regulation of organelle organizationGO:00330431960.037
regulation of small gtpase mediated signal transductionGO:0051056930.037
establishment or maintenance of bipolar cell polarityGO:0061245340.036
digestive system developmentGO:00551231490.036
regulation of phosphate metabolic processGO:00192202100.036
gene silencing by rnaGO:0031047570.036
establishment or maintenance of cytoskeleton polarityGO:0030952440.035
oocyte constructionGO:00073081120.035
regulation of multicellular organismal developmentGO:20000264140.035
protein localizationGO:00081042840.035
negative regulation of nucleic acid templated transcriptionGO:19035072400.035
negative regulation of cellular biosynthetic processGO:00313272770.034
dendrite morphogenesisGO:00488131990.034
imaginal disc derived wing morphogenesisGO:00074763370.034
taxisGO:00423303040.034
cell deathGO:00082192790.034
single organism intracellular transportGO:19025822070.033
embryonic pattern specificationGO:00098801740.033
regulation of mitotic cell cycle phase transitionGO:19019901300.033
microtubule organizing center organizationGO:00310231680.033
male meiosis chromosome segregationGO:0007060100.032
proteasomal protein catabolic processGO:0010498590.032
eye morphogenesisGO:00485922600.032
negative regulation of macromolecule biosynthetic processGO:00105582700.032
regulation of cellular amine metabolic processGO:003323830.032
female meiotic divisionGO:0007143700.031
negative regulation of biosynthetic processGO:00098902770.031
regulation of transcription from rna polymerase ii promoterGO:00063573780.031
regulation of cell proliferationGO:00421271630.031
axis specificationGO:00097981670.031
chemotaxisGO:00069352490.031
axonogenesisGO:00074092900.031
cellular macromolecule catabolic processGO:00442651360.030
embryonic development via the syncytial blastodermGO:00017001480.030
dna integrity checkpointGO:0031570810.030
glycosyl compound metabolic processGO:19016571270.030
dorsal ventral pattern formationGO:00099531330.030
photoreceptor cell differentiationGO:00465301700.030
mitotic cytokinesisGO:0000281500.029
positive regulation of gene expressionGO:00106282900.029
eye photoreceptor cell developmentGO:0042462810.029
small gtpase mediated signal transductionGO:0007264880.028
regulation of cell cycle phase transitionGO:19019871300.028
apoptotic processGO:00069151590.028
wing disc morphogenesisGO:00074723440.028
positive regulation of response to stimulusGO:00485843230.028
organic substance catabolic processGO:19015753080.027
response to radiationGO:00093141550.027
nucleoside metabolic processGO:00091161270.026
embryonic axis specificationGO:00005781070.026
catabolic processGO:00090564090.026
carbohydrate derivative catabolic processGO:19011361180.026
purine nucleoside metabolic processGO:00422781270.026
positive regulation of nucleotide catabolic processGO:0030813460.026
meiotic cell cycle processGO:19030461320.026
phagocytosisGO:00069092150.026
dna metabolic processGO:00062592270.026
regulation of cell sizeGO:0008361630.026
posttranscriptional gene silencing by rnaGO:0035194450.026
cellularizationGO:0007349900.025
immune responseGO:00069552460.025
single organism catabolic processGO:00447122280.025
nucleoside phosphate metabolic processGO:00067531620.025
cell recognitionGO:00080371020.025
digestive tract morphogenesisGO:00485461270.025
ribonucleotide metabolic processGO:00092591450.025
single organism behaviorGO:00447083910.025
mitotic sister chromatid separationGO:0051306300.024
chitin based cuticle developmentGO:0040003490.024
regulation of phosphorus metabolic processGO:00511742100.024
endocytosisGO:00068973100.024
regulation of cell cycle processGO:00105641810.024
regulation of catalytic activityGO:00507901850.024
g2 m transition of mitotic cell cycleGO:0000086190.024
regulation of molecular functionGO:00650092170.024
regulation of response to stressGO:00801342000.024
retina development in camera type eyeGO:006004140.023
positive regulation of phosphate metabolic processGO:00459371390.023
segmentationGO:00352822070.023
ras protein signal transductionGO:0007265880.023
dna repairGO:0006281540.023
intracellular transportGO:00469072280.023
protein modification by small protein conjugation or removalGO:00706471060.023
compound eye photoreceptor cell differentiationGO:00017511400.023
anatomical structure homeostasisGO:0060249970.023
g2 dna damage checkpointGO:0031572690.022
tripartite regional subdivisionGO:00073511030.022
regulation of transportGO:00510491810.022
small molecule metabolic processGO:00442813050.022
ribonucleoside catabolic processGO:00424541120.022
neuron projection guidanceGO:00974852410.022
macromolecule catabolic processGO:00090571610.022
blastoderm segmentationGO:00073501590.021
oocyte differentiationGO:00099941450.021
antimicrobial humoral responseGO:0019730990.021
histone mrna metabolic processGO:000833480.021
axon developmentGO:00615642970.021
intracellular signal transductionGO:00355563000.021
regulation of synapse organizationGO:00508071100.021
nucleotide metabolic processGO:00091171610.021
positive regulation of cellular component organizationGO:00511301560.021
establishment or maintenance of cell polarityGO:00071631670.021
positive regulation of catabolic processGO:00098961050.021
positive regulation of nitrogen compound metabolic processGO:00511733540.021
response to woundingGO:0009611940.021
proteolysisGO:00065081920.021
regulation of cell maturationGO:1903429270.021
meiotic cell cycleGO:00513211710.021
regulation of ras protein signal transductionGO:0046578930.020
meiotic chromosome segregationGO:0045132590.020
organophosphate metabolic processGO:00196371950.020
cellular nitrogen compound catabolic processGO:00442701650.020
defense responseGO:00069523000.020
open tracheal system developmentGO:00074242040.020
morphogenesis of an epitheliumGO:00020092760.020
nucleobase containing compound catabolic processGO:00346551650.020
regulation of oocyte developmentGO:0060281270.020
regulation of cell developmentGO:00602842150.020
regulation of immune system processGO:00026821760.020
meiotic nuclear divisionGO:00071261510.019
kidney developmentGO:000182230.019
oocyte anterior posterior axis specificationGO:0007314720.019
response to ionizing radiationGO:0010212320.019
regulation of catabolic processGO:00098941700.019
metaphase anaphase transition of cell cycleGO:0044784280.019
regulation of cellular ketone metabolic processGO:001056530.019
imaginal disc derived appendage morphogenesisGO:00351143950.019
photoreceptor cell developmentGO:0042461960.019
positive regulation of signal transductionGO:00099672230.019
axon guidanceGO:00074112330.019
organic acid metabolic processGO:00060821030.019
imaginal disc pattern formationGO:0007447910.018
cellular protein catabolic processGO:0044257830.018
anterior posterior axis specification embryoGO:00085951030.018
tissue morphogenesisGO:00487292970.018
maternal determination of anterior posterior axis embryoGO:0008358740.018
protein catabolic processGO:00301631010.018
chromosome condensationGO:0030261410.018
regulation of sister chromatid segregationGO:0033045280.018
nucleoside triphosphate catabolic processGO:00091431080.018
fertilizationGO:0009566260.018
negative regulation of signalingGO:00230572190.018
syncytial blastoderm mitotic cell cycleGO:0035186210.018
response to fungusGO:0009620500.018
intracellular protein transportGO:00068861040.018
pole cell formationGO:0007279190.017
microtubule anchoringGO:0034453110.017
regulation of cellular catabolic processGO:00313291570.017
cuticle developmentGO:0042335860.017
intracellular mrna localization involved in anterior posterior axis specificationGO:0060811530.017
modification dependent macromolecule catabolic processGO:0043632790.017
nephron morphogenesisGO:007202830.017
ribonucleoside triphosphate catabolic processGO:00092031080.017
respiratory system developmentGO:00605412130.017
nucleobase containing small molecule metabolic processGO:00550861740.017
larval developmentGO:00021641040.017
developmental programmed cell deathGO:00106231380.017
negative regulation of nucleobase containing compound metabolic processGO:00459342610.017
endodermal cell differentiationGO:003598730.017
neurological system processGO:00508773580.017
negative regulation of protein metabolic processGO:0051248850.017
organonitrogen compound catabolic processGO:19015651280.016
aromatic compound catabolic processGO:00194391660.016
negative regulation of cell cycle processGO:00109481090.016
homeostatic processGO:00425921990.016
epithelial cell differentiationGO:00308553220.016
cellular ketone metabolic processGO:0042180240.016
mrna metabolic processGO:00160711240.016
purine nucleotide metabolic processGO:00061631460.016
protein phosphorylationGO:00064681690.016
regulation of cell deathGO:00109411730.016
carbohydrate derivative metabolic processGO:19011352170.016
eye photoreceptor cell differentiationGO:00017541450.016
negative regulation of gene expression epigeneticGO:0045814770.016
pole plasm assemblyGO:0007315610.016
regulation of chromosome segregationGO:0051983320.016
camera type eye developmentGO:004301040.016
regulation of synapse structure and activityGO:00508031280.016
purine nucleotide catabolic processGO:00061951090.016
innate immune responseGO:00450871440.016
organic cyclic compound catabolic processGO:19013611680.016
nucleoside triphosphate metabolic processGO:00091411200.016
nuclear dna replicationGO:003326010.016
developmental growthGO:00485892800.016
establishment or maintenance of microtubule cytoskeleton polarityGO:0030951410.016
female meiosis iGO:000714480.016
regulation of phosphorylationGO:00423251470.015
appendage developmentGO:00487364010.015
regulation of endocytosisGO:0030100370.015
positive regulation of catalytic activityGO:00430851180.015
digestive tract developmentGO:00485651490.015
response to lipopolysaccharideGO:003249640.015
response to biotic stimulusGO:00096072940.015
nephron developmentGO:007200630.015
regulation of protein localizationGO:0032880760.015
tube developmentGO:00352952440.015
growthGO:00400073590.015
stem cell maintenanceGO:0019827670.015
cell motilityGO:00488702510.015
dendrite developmentGO:00163582040.015
negative regulation of cellular protein metabolic processGO:0032269850.015
guanosine containing compound metabolic processGO:1901068740.015
synaptic transmissionGO:00072682880.015
positive regulation of multicellular organismal processGO:00512401430.015
compound eye photoreceptor developmentGO:0042051780.015
response to hypoxiaGO:0001666530.015
positive regulation of phosphorus metabolic processGO:00105621390.015
carboxylic acid metabolic processGO:0019752920.015
organic substance transportGO:00717022570.015
negative regulation of cell differentiationGO:00455961430.015
protein complex biogenesisGO:00702712010.015
regulation of cellular response to stressGO:0080135890.014
peptidyl amino acid modificationGO:00181931050.014
purine ribonucleoside triphosphate metabolic processGO:00092051190.014
positive regulation of proteolysisGO:0045862520.014
secretionGO:00469031090.014
response to other organismGO:00517072930.014
hematopoietic progenitor cell differentiationGO:000224410.014
negative regulation of transcription dna templatedGO:00458922370.014
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.014
hemopoiesisGO:0030097460.014
regulation of mitotic metaphase anaphase transitionGO:0030071260.014
synapse organizationGO:00508081960.014
positive regulation of transcription dna templatedGO:00458932660.014
forebrain developmentGO:003090020.014
g1 s transition of mitotic cell cycleGO:0000082310.014
tube morphogenesisGO:00352391910.014
cell cycle g1 s phase transitionGO:0044843310.014
negative regulation of cell deathGO:0060548810.014
oocyte microtubule cytoskeleton organizationGO:0016325350.014
regulation of gene silencingGO:0060968630.014
regulation of cellular amino acid metabolic processGO:000652100.014
cytoplasm organizationGO:0007028640.014
oocyte dorsal ventral axis specificationGO:0007310340.014
terminal region determinationGO:0007362250.014
regulation of embryonic developmentGO:0045995680.014
mitotic recombinationGO:000631220.014
wing disc pattern formationGO:0035222660.014
pronuclear fusionGO:000734440.014
regulation of gene expression epigeneticGO:00400291280.014
mrna polyadenylationGO:0006378110.014
modification dependent protein catabolic processGO:0019941780.014
response to oxygen containing compoundGO:19017002000.014
reproductive system developmentGO:0061458740.013
pole plasm oskar mrna localizationGO:0045451460.013
ubiquitin dependent protein catabolic processGO:0006511780.013
negative regulation of cell cycleGO:00457861160.013
pole plasm rna localizationGO:0007316520.013
cellular amine metabolic processGO:0044106120.013
cytoplasmic transportGO:00164821300.013
reproductive structure developmentGO:0048608740.013
heterocycle catabolic processGO:00467001660.013
regulation of protein metabolic processGO:00512462560.013
epidermal growth factor receptor signaling pathwayGO:0007173580.013
regulation of gtpase activityGO:0043087440.013
mitotic g2 dna damage checkpointGO:0007095690.013
cellular response to external stimulusGO:0071496660.013
single organism biosynthetic processGO:00447112060.013
positive regulation of signalingGO:00230562430.013
establishment of rna localizationGO:0051236470.013
positive regulation of cellular catabolic processGO:0031331950.013
organonitrogen compound metabolic processGO:19015643180.013
dorsal ventral axis specificationGO:0009950660.013
chromatin organizationGO:00063252070.013
chromatin silencingGO:0006342760.013
positive regulation of ras protein signal transductionGO:0046579430.013
molting cycleGO:0042303560.013
regulation of response to biotic stimulusGO:0002831630.013
regulation of response to external stimulusGO:00321011150.013
rna 3 end processingGO:0031123450.013
rna processingGO:00063961470.013
cellular component assembly involved in morphogenesisGO:00109271510.013
germarium derived egg chamber formationGO:00072931010.013
regulation of protein catabolic processGO:0042176550.013
synaptic growth at neuromuscular junctionGO:00511241190.013
purine ribonucleotide metabolic processGO:00091501450.013
nuclear divisionGO:00002803320.013
regulation of cellular protein metabolic processGO:00322682430.012
regulation of immune responseGO:00507761180.012
purine containing compound metabolic processGO:00725211550.012
protein modification by small protein conjugationGO:0032446790.012
nucleoside phosphate catabolic processGO:19012921100.012
protein deubiquitinationGO:0016579170.012
proteolysis involved in cellular protein catabolic processGO:0051603830.012
positive regulation of phosphorylationGO:0042327870.012
negative regulation of response to stimulusGO:00485852580.012
ribonucleoside triphosphate metabolic processGO:00091991190.012
purine ribonucleoside triphosphate catabolic processGO:00092071080.012
regulation of mitotic sister chromatid separationGO:0010965280.012
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.012
guanosine containing compound catabolic processGO:1901069740.012
lateral inhibitionGO:00463312060.012
dna conformation changeGO:00711031050.012
mitotic chromosome condensationGO:0007076220.012
neuroblast proliferationGO:0007405740.012
positive regulation of purine nucleotide metabolic processGO:1900544550.012
regulation of retinal cell programmed cell deathGO:0046668180.012
positive regulation of cell communicationGO:00106472500.012
purine nucleoside triphosphate metabolic processGO:00091441190.012
regulation of multi organism processGO:00439001310.012
intracellular mrna localization involved in pattern specification processGO:0060810560.012
regulation of chromosome organizationGO:0033044640.012
chromatin modificationGO:00165681470.012
central nervous system developmentGO:00074172010.012
positive regulation of cell motilityGO:200014730.012
cellular response to biotic stimulusGO:007121640.012
regulation of developmental growthGO:00486381740.012
positive regulation of nucleotide metabolic processGO:0045981550.012
negative regulation of chromosome segregationGO:0051985140.012
protein targeting to nucleusGO:0044744510.012
rna polyadenylationGO:0043631120.012
positive regulation of cellular amino acid metabolic processGO:004576400.012
cellular response to chemical stimulusGO:00708871990.012
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.011
muscle cell differentiationGO:00426921030.011
protein transportGO:00150311550.011
positive regulation of transportGO:0051050920.011
regulation of cell divisionGO:0051302720.011
cellular macromolecule localizationGO:00707272200.011
chromosome separationGO:0051304420.011
protein targetingGO:0006605640.011
pole cell developmentGO:0007277260.011
dna geometric changeGO:0032392160.011
response to decreased oxygen levelsGO:0036293580.011
karyogamyGO:000074140.011
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.011
ribose phosphate metabolic processGO:00196931450.011
amine metabolic processGO:0009308120.011
rna interferenceGO:0016246270.011
histolysisGO:00075591020.011
purine ribonucleotide catabolic processGO:00091541090.011
wound healingGO:0042060750.011
cellular response to lipopolysaccharideGO:007122230.011
regulation of chromatin silencingGO:0031935360.011
neuromuscular junction developmentGO:00075281490.011
segment specificationGO:0007379330.011
pole plasm mrna localizationGO:0019094490.011
lipopolysaccharide mediated signaling pathwayGO:003166310.011
spermatogenesisGO:00072832000.011
eggshell chorion assemblyGO:0007306660.011
regulation of purine nucleotide metabolic processGO:1900542620.011
purine nucleoside catabolic processGO:00061521120.011
negative regulation of cell cycle g2 m phase transitionGO:190275080.011
metaphase anaphase transition of mitotic cell cycleGO:0007091280.011
response to oxygen levelsGO:0070482590.011
mesenchymal cell developmentGO:001403110.011
endomembrane system organizationGO:00102561190.011
positive regulation of cellular amine metabolic processGO:003324000.010
extracellular matrix constituent secretionGO:007027840.010
nephron epithelium developmentGO:007200930.010
tissue deathGO:00162711020.010
regulation of mitotic sister chromatid segregationGO:0033047280.010
negative regulation of growthGO:0045926840.010
ribonucleotide catabolic processGO:00092611090.010
rna transportGO:0050658460.010
renal tubule developmentGO:0061326640.010
nucleobase containing compound transportGO:0015931560.010
positive regulation of macromolecule metabolic processGO:00106044050.010
germarium derived female germ line cyst formationGO:0030727420.010
regulation of alternative mrna splicing via spliceosomeGO:0000381600.010
regulation of apoptotic processGO:00429811300.010
response to organic substanceGO:00100332840.010
gtp metabolic processGO:0046039720.010
positive regulation of ras gtpase activityGO:0032320360.010
organophosphate catabolic processGO:00464341120.010
regulation of proteasomal protein catabolic processGO:0061136390.010
single organism nuclear importGO:1902593510.010
membrane organizationGO:00610241120.010

Xpd disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.036
disease of cellular proliferationDOID:1456600.036
organ system cancerDOID:005068600.012
connective tissue diseaseDOID:6500.010
disease of anatomical entityDOID:700.010
musculoskeletal system diseaseDOID:1700.010
disease of metabolismDOID:001466700.010