Drosophila melanogaster

15 known processes

Ubc-E2H (Dmel_CG2257)

CG2257 gene product from transcript CG2257-RA

(Aliases: CG2257,Dmel\CG2257,dUbc-E2H,UbcE2H)

Ubc-E2H biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of cell communicationGO:00106482230.317
protein modification processGO:00362114380.299
Human Yeast Mouse
cellular response to dna damage stimulusGO:00069742230.174
regulation of cell differentiationGO:00455953020.161
regulation of growthGO:00400082330.156
macromolecular complex assemblyGO:00650032560.133
membrane organizationGO:00610241120.127
nucleobase containing compound catabolic processGO:00346551650.122
organophosphate metabolic processGO:00196371950.121
establishment of localization in cellGO:00516494020.118
growthGO:00400073590.117
intracellular transportGO:00469072280.115
cell cell signaling involved in cell fate commitmentGO:00451682100.114
protein complex biogenesisGO:00702712010.114
regulation of cellular localizationGO:00603411360.112
single organism membrane organizationGO:0044802930.109
organic substance transportGO:00717022570.108
establishment or maintenance of cell polarityGO:00071631670.108
carbohydrate derivative catabolic processGO:19011361180.095
catabolic processGO:00090564090.095
Yeast Mouse
regulation of localizationGO:00328792750.094
immune system processGO:00023763470.093
response to organic substanceGO:00100332840.090
spermatid developmentGO:0007286980.085
response to lipopolysaccharideGO:003249640.081
heterocycle catabolic processGO:00467001660.077
organonitrogen compound metabolic processGO:19015643180.076
vesicle mediated transportGO:00161923810.075
muscle structure developmentGO:00610612240.072
purine nucleoside metabolic processGO:00422781270.072
male gamete generationGO:00482322010.069
ribonucleoside metabolic processGO:00091191270.069
purine nucleoside triphosphate metabolic processGO:00091441190.068
organic substance catabolic processGO:19015753080.064
Yeast Mouse
tube developmentGO:00352952440.063
gland developmentGO:00487321910.063
imaginal disc derived appendage developmentGO:00487373990.060
nucleobase containing small molecule metabolic processGO:00550861740.060
negative regulation of cellular metabolic processGO:00313243820.059
Yeast
nucleoside metabolic processGO:00091161270.058
protein complex assemblyGO:00064612000.058
negative regulation of signalingGO:00230572190.058
aromatic compound catabolic processGO:00194391660.058
endocytosisGO:00068973100.057
immune responseGO:00069552460.056
peptidyl amino acid modificationGO:00181931050.054
purine nucleotide metabolic processGO:00061631460.051
regulation of multicellular organismal developmentGO:20000264140.050
regulation of anatomical structure sizeGO:00900661630.049
regulation of cell cycleGO:00517262910.049
single organism cellular localizationGO:19025801800.049
tissue deathGO:00162711020.049
lateral inhibitionGO:00463312060.048
small molecule metabolic processGO:00442813050.048
Yeast
cell divisionGO:00513012480.047
organic cyclic compound catabolic processGO:19013611680.046
cellular catabolic processGO:00442483720.046
Yeast Mouse
tube morphogenesisGO:00352391910.045
response to oxygen containing compoundGO:19017002000.045
purine ribonucleoside metabolic processGO:00461281270.044
cellular nitrogen compound catabolic processGO:00442701650.044
cell motilityGO:00488702510.044
single organism catabolic processGO:00447122280.043
nucleotide metabolic processGO:00091171610.043
ribonucleoside catabolic processGO:00424541120.043
purine containing compound catabolic processGO:00725231120.043
negative regulation of signal transductionGO:00099682060.042
regulation of production of molecular mediator of immune responseGO:0002700440.042
cellular response to organic substanceGO:00713101320.042
organelle fusionGO:0048284460.042
ribonucleotide metabolic processGO:00092591450.042
protein heterooligomerizationGO:005129140.041
organelle assemblyGO:00709251980.040
spermatid differentiationGO:00485151140.040
acetylcholine metabolic processGO:000829120.039
regulation of cellular catabolic processGO:00313291570.038
regulation of organelle organizationGO:00330431960.038
salivary gland developmentGO:00074311620.038
transcription from rna polymerase ii promoterGO:00063663680.038
negative regulation of response to stimulusGO:00485852580.037
response to external biotic stimulusGO:00432072930.037
purine containing compound metabolic processGO:00725211550.035
spermatogenesisGO:00072832000.035
ribose phosphate metabolic processGO:00196931450.034
response to other organismGO:00517072930.034
purine nucleoside catabolic processGO:00061521120.034
cellular macromolecule localizationGO:00707272200.033
cellular protein localizationGO:00346131600.032
regulation of immune effector processGO:0002697520.032
guanosine containing compound catabolic processGO:1901069740.030
appendage morphogenesisGO:00351073970.030
carboxylic acid metabolic processGO:0019752920.030
gland morphogenesisGO:00226121450.030
cytoplasmic transportGO:00164821300.030
regulation of transportGO:00510491810.030
imaginal disc derived appendage morphogenesisGO:00351143950.029
muscle cell differentiationGO:00426921030.029
protein transportGO:00150311550.029
cellular amine metabolic processGO:0044106120.028
cellular protein complex assemblyGO:0043623710.028
purine ribonucleoside triphosphate catabolic processGO:00092071080.028
cell deathGO:00082192790.028
regulation of cellular protein metabolic processGO:00322682430.027
regulation of transcription from rna polymerase ii promoterGO:00063573780.027
histolysisGO:00075591020.027
purine ribonucleoside triphosphate metabolic processGO:00092051190.027
actin cytoskeleton organizationGO:00300362060.027
purine ribonucleotide catabolic processGO:00091541090.027
establishment of protein localizationGO:00451841630.026
regulation of molecular functionGO:00650092170.026
exocrine system developmentGO:00352721620.026
secretionGO:00469031090.026
nucleoside phosphate metabolic processGO:00067531620.026
body morphogenesisGO:001017120.026
response to bacteriumGO:00096171980.025
post embryonic appendage morphogenesisGO:00351203850.025
salivary gland morphogenesisGO:00074351450.025
regulation of embryonic cell shapeGO:0016476300.025
meiotic cell cycleGO:00513211710.025
protein localizationGO:00081042840.025
regulation of cell sizeGO:0008361630.025
purine ribonucleoside catabolic processGO:00461301120.024
cellular response to extracellular stimulusGO:0031668640.024
purine ribonucleotide metabolic processGO:00091501450.023
regulation of response to stressGO:00801342000.023
ribonucleoside triphosphate metabolic processGO:00091991190.023
regulation of protein metabolic processGO:00512462560.023
appendage developmentGO:00487364010.023
glycosyl compound metabolic processGO:19016571270.023
protein catabolic processGO:00301631010.023
Yeast Mouse
negative regulation of cell cycle phase transitionGO:19019881030.023
defense responseGO:00069523000.023
cellular component assembly involved in morphogenesisGO:00109271510.022
phagocytosisGO:00069092150.022
salivary gland histolysisGO:0035070880.022
positive regulation of nucleobase containing compound metabolic processGO:00459353320.021
cellular response to chemical stimulusGO:00708871990.021
regulation of compound eye retinal cell programmed cell deathGO:0046669180.021
organic acid metabolic processGO:00060821030.021
purine nucleotide catabolic processGO:00061951090.021
regulation of defense responseGO:00313471020.021
ribonucleoside triphosphate catabolic processGO:00092031080.020
positive regulation of cellular component organizationGO:00511301560.020
single organism intracellular transportGO:19025822070.020
regulation of hydrolase activityGO:0051336970.020
agingGO:00075681430.020
response to woundingGO:0009611940.020
cell proliferationGO:00082832990.020
developmental programmed cell deathGO:00106231380.020
nucleoside triphosphate metabolic processGO:00091411200.019
mitotic cell cycle checkpointGO:0007093880.019
regulation of secretion by cellGO:1903530390.019
proteolysisGO:00065081920.019
Yeast Mouse
multicellular organism growthGO:0035264460.019
positive regulation of catabolic processGO:00098961050.018
organophosphate catabolic processGO:00464341120.018
negative regulation of mitotic cell cycle phase transitionGO:19019911030.018
multi organism behaviorGO:00517051750.018
glycosyl compound catabolic processGO:19016581120.018
dna damage checkpointGO:0000077780.018
apoptotic processGO:00069151590.018
cell migrationGO:00164772380.018
wing disc morphogenesisGO:00074723440.017
salivary gland cell autophagic cell deathGO:0035071830.017
oxoacid metabolic processGO:00434361030.017
lipid metabolic processGO:00066291210.017
autophagic cell deathGO:0048102830.017
regulation of cellular component biogenesisGO:00440872010.017
regulation of developmental growthGO:00486381740.017
positive regulation of nitrogen compound metabolic processGO:00511733540.017
positive regulation of developmental processGO:00510941430.017
dna integrity checkpointGO:0031570810.017
macromolecule catabolic processGO:00090571610.017
Yeast Mouse
regulation of macroautophagyGO:0016241150.017
lipid localizationGO:0010876540.016
nucleotide catabolic processGO:00091661090.016
ribonucleotide catabolic processGO:00092611090.016
asymmetric stem cell divisionGO:0098722490.016
response to biotic stimulusGO:00096072940.016
imaginal disc derived wing morphogenesisGO:00074763370.015
actin filament based processGO:00300292200.015
striated muscle cell differentiationGO:0051146900.015
positive regulation of immune effector processGO:0002699280.015
wnt signaling pathwayGO:0016055980.015
negative regulation of cellular biosynthetic processGO:00313272770.015
Yeast
organelle fissionGO:00482853400.015
negative regulation of growthGO:0045926840.015
synaptic transmissionGO:00072682880.015
regulation of cell shapeGO:00083601130.015
regulation of tube sizeGO:0035150460.015
male meiosisGO:0007140520.015
regulation of catabolic processGO:00098941700.015
neuron remodelingGO:0016322290.014
regulation of cellular component sizeGO:0032535980.014
positive regulation of transportGO:0051050920.014
regulation of golgi to plasma membrane protein transportGO:004299660.014
positive regulation of production of molecular mediator of immune responseGO:0002702280.014
amine metabolic processGO:0009308120.014
hemopoiesisGO:0030097460.014
negative regulation of nitrogen compound metabolic processGO:00511722650.014
stress activated protein kinase signaling cascadeGO:0031098550.014
programmed cell deathGO:00125012570.014
autophagyGO:00069141080.014
positive regulation of immune system processGO:0002684680.014
antimicrobial peptide biosynthetic processGO:0002777380.013
regulation of protein localizationGO:0032880760.013
regulation of catalytic activityGO:00507901850.013
phosphorylationGO:00163102940.013
regulation of cell morphogenesisGO:00226041630.013
neuroblast proliferationGO:0007405740.013
immune effector processGO:0002252980.013
innate immune response activating signal transductionGO:000275820.013
secretion by cellGO:00329401010.013
larval developmentGO:00021641040.013
cellular amide metabolic processGO:0043603800.013
positive regulation of defense responseGO:0031349590.013
humoral immune responseGO:00069591170.013
lipid modificationGO:0030258240.013
response to organonitrogen compoundGO:0010243750.013
positive regulation of cellular biosynthetic processGO:00313283160.013
regulation of apoptotic processGO:00429811300.013
guanosine containing compound metabolic processGO:1901068740.013
urogenital system developmentGO:0001655720.012
epithelial tube morphogenesisGO:0060562880.012
nucleoside triphosphate catabolic processGO:00091431080.012
organonitrogen compound catabolic processGO:19015651280.012
response to starvationGO:0042594970.012
jnk cascadeGO:0007254500.012
response to nutrient levelsGO:00316671140.012
compound eye developmentGO:00487493070.012
regulation of anatomical structure morphogenesisGO:00226032420.012
stress activated mapk cascadeGO:0051403520.012
regulation of phosphatase activityGO:001092130.012
single organism behaviorGO:00447083910.012
immune system developmentGO:0002520570.012
positive regulation of multi organism processGO:0043902400.012
regulation of hemocyte proliferationGO:0035206370.012
cellularizationGO:0007349900.012
negative regulation of protein metabolic processGO:0051248850.012
maintenance of location in cellGO:0051651280.011
defense response to gram negative bacteriumGO:0050829940.011
gtp metabolic processGO:0046039720.011
endocytic recyclingGO:0032456130.011
positive regulation of cellular component biogenesisGO:0044089800.011
regulation of secretionGO:0051046440.011
regulation of asymmetric cell divisionGO:000978630.011
regulation of proteolysisGO:0030162870.011
dendrite developmentGO:00163582040.011
endomembrane system organizationGO:00102561190.011
localization of cellGO:00516742570.011
purine ribonucleoside monophosphate metabolic processGO:0009167500.011
chromosome organizationGO:00512763600.011
hematopoietic progenitor cell differentiationGO:000224410.011
carbohydrate derivative metabolic processGO:19011352170.011
sensory organ morphogenesisGO:00905962600.011
production of molecular mediator of immune responseGO:0002440460.011
synaptic growth at neuromuscular junctionGO:00511241190.011
regulation of response to external stimulusGO:00321011150.011
developmental growthGO:00485892800.011
antimicrobial peptide productionGO:0002775460.010
cellular response to oxygen containing compoundGO:1901701790.010
defense response to virusGO:0051607230.010
neural precursor cell proliferationGO:0061351750.010
macroautophagyGO:0016236420.010
compound eye photoreceptor cell differentiationGO:00017511400.010
convergent extensionGO:006002620.010
forebrain developmentGO:003090020.010
gtp catabolic processGO:0006184720.010
response to extracellular stimulusGO:00099911160.010
positive regulation of protein localization to plasma membraneGO:190307830.010
muscle cell developmentGO:0055001500.010
positive regulation of molecular functionGO:00440931360.010
establishment of protein localization to organelleGO:0072594620.010

Ubc-E2H disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.045
nervous system diseaseDOID:86300.014
central nervous system diseaseDOID:33100.014
bone diseaseDOID:008000100.011
connective tissue diseaseDOID:6500.011
musculoskeletal system diseaseDOID:1700.011
osteogenesis imperfectaDOID:1234700.011
bone development diseaseDOID:008000600.011
osteochondrodysplasiaDOID:225600.011