Drosophila melanogaster

0 known processes

H2.0 (Dmel_CG11607)

Homeodomain protein 2.0

(Aliases: CG11607,Dmel\CG11607)

H2.0 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
tube morphogenesisGO:00352391910.187
Mouse
tube developmentGO:00352952440.146
Mouse
positive regulation of nucleic acid templated transcriptionGO:19035082660.145
tissue morphogenesisGO:00487292970.125
regulation of transcription from rna polymerase ii promoterGO:00063573780.115
negative regulation of rna biosynthetic processGO:19026792400.110
positive regulation of gene expressionGO:00106282900.107
post embryonic appendage morphogenesisGO:00351203850.095
growthGO:00400073590.095
Mouse
imaginal disc derived wing morphogenesisGO:00074763370.090
morphogenesis of an epitheliumGO:00020092760.090
embryonic morphogenesisGO:00485982060.090
Mouse
appendage developmentGO:00487364010.088
imaginal disc derived appendage morphogenesisGO:00351143950.085
positive regulation of transcription dna templatedGO:00458932660.084
positive regulation of rna metabolic processGO:00512542710.083
positive regulation of cellular biosynthetic processGO:00313283160.082
appendage morphogenesisGO:00351073970.080
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.079
wing disc morphogenesisGO:00074723440.079
brain developmentGO:00074201200.079
Fly
positive regulation of macromolecule biosynthetic processGO:00105572830.078
anterior posterior pattern specificationGO:00099521360.077
imaginal disc derived appendage developmentGO:00487373990.074
digestive system developmentGO:00551231490.071
Mouse
negative regulation of gene expressionGO:00106293870.071
compound eye developmentGO:00487493070.068
locomotory behaviorGO:00076261760.066
positive regulation of rna biosynthetic processGO:19026802660.065
photoreceptor cell differentiationGO:00465301700.065
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.065
sensory organ morphogenesisGO:00905962600.063
digestive tract morphogenesisGO:00485461270.063
Mouse
neurological system processGO:00508773580.062
positive regulation of nucleobase containing compound metabolic processGO:00459353320.060
hindgut morphogenesisGO:0007442580.058
negative regulation of macromolecule biosynthetic processGO:00105582700.058
eye developmentGO:00016543230.057
positive regulation of nitrogen compound metabolic processGO:00511733540.056
hindbrain developmentGO:003090220.055
regulation of cell differentiationGO:00455953020.053
Mouse
negative regulation of cellular biosynthetic processGO:00313272770.053
head developmentGO:00603221350.052
Fly
detection of stimulusGO:00516061560.051
negative regulation of rna metabolic processGO:00512532510.051
negative regulation of cellular metabolic processGO:00313243820.050
cell deathGO:00082192790.049
open tracheal system developmentGO:00074242040.049
negative regulation of transcription dna templatedGO:00458922370.049
response to abiotic stimulusGO:00096283410.049
response to organic substanceGO:00100332840.048
compound eye morphogenesisGO:00017452490.048
negative regulation of nucleic acid templated transcriptionGO:19035072400.047
eye morphogenesisGO:00485922600.047
epithelial tube morphogenesisGO:0060562880.045
positive regulation of biosynthetic processGO:00098913160.045
negative regulation of signalingGO:00230572190.044
taxisGO:00423303040.043
regulation of multicellular organismal developmentGO:20000264140.042
Mouse
response to light stimulusGO:00094161240.042
negative regulation of developmental processGO:00510932010.042
Mouse
small molecule metabolic processGO:00442813050.041
single organism behaviorGO:00447083910.041
regionalizationGO:00030024160.041
establishment or maintenance of cell polarityGO:00071631670.041
negative regulation of biosynthetic processGO:00098902770.040
negative regulation of response to stimulusGO:00485852580.039
Mouse
kidney developmentGO:000182230.039
dendrite morphogenesisGO:00488131990.039
regulation of localizationGO:00328792750.038
negative regulation of signal transductionGO:00099682060.038
catabolic processGO:00090564090.038
respiratory system developmentGO:00605412130.038
negative regulation of nucleobase containing compound metabolic processGO:00459342610.038
embryonic development via the syncytial blastodermGO:00017001480.037
positive regulation of macromolecule metabolic processGO:00106044050.037
actin cytoskeleton organizationGO:00300362060.036
regulation of anatomical structure morphogenesisGO:00226032420.035
digestive tract developmentGO:00485651490.035
Mouse
compound eye photoreceptor cell differentiationGO:00017511400.034
negative regulation of cell differentiationGO:00455961430.033
Mouse
embryonic organ developmentGO:0048568500.033
Mouse
eye photoreceptor cell differentiationGO:00017541450.033
negative regulation of nitrogen compound metabolic processGO:00511722650.033
branching morphogenesis of an epithelial tubeGO:0048754450.032
male gamete generationGO:00482322010.031
malpighian tubule developmentGO:0072002640.030
positive regulation of cellular amino acid metabolic processGO:004576400.030
camera type eye developmentGO:004301040.030
body morphogenesisGO:001017120.029
protein modification processGO:00362114380.028
negative regulation of multicellular organismal processGO:00512411420.028
Mouse
embryonic pattern specificationGO:00098801740.028
renal tubule developmentGO:0061326640.028
regulation of response to external stimulusGO:00321011150.028
connective tissue developmentGO:006144830.028
cellular protein modification processGO:00064644380.028
morphogenesis of embryonic epitheliumGO:0016331940.028
positive regulation of signalingGO:00230562430.028
regulation of cellular ketone metabolic processGO:001056530.028
regulation of phosphorus metabolic processGO:00511742100.028
pigmentationGO:0043473750.028
stem cell differentiationGO:00488631170.027
intracellular signal transductionGO:00355563000.027
wnt signaling pathwayGO:0016055980.027
establishment of localization in cellGO:00516494020.027
gland morphogenesisGO:00226121450.027
regulation of embryonic developmentGO:0045995680.027
forebrain developmentGO:003090020.026
regulation of cell morphogenesisGO:00226041630.026
regulation of cell cycle processGO:00105641810.026
regulation of intracellular signal transductionGO:19025312360.026
morphogenesis of a branching epitheliumGO:0061138450.025
central nervous system developmentGO:00074172010.025
Fly
cell cell junction organizationGO:0045216550.025
carbohydrate derivative metabolic processGO:19011352170.025
negative regulation of cell communicationGO:00106482230.025
imaginal disc pattern formationGO:0007447910.024
response to radiationGO:00093141550.024
regulation of cellular amino acid metabolic processGO:000652100.024
nephron developmentGO:007200630.024
salivary gland developmentGO:00074311620.023
transcription from rna polymerase ii promoterGO:00063663680.023
anterior posterior axis specificationGO:00099481090.023
embryo development ending in birth or egg hatchingGO:00097921520.023
positive regulation of cell communicationGO:00106472500.023
nuclear divisionGO:00002803320.023
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.023
ameboidal type cell migrationGO:00016671510.023
salivary gland morphogenesisGO:00074351450.023
positive regulation of response to stimulusGO:00485843230.022
Mouse
chromatin organizationGO:00063252070.022
developmental programmed cell deathGO:00106231380.022
regulation of phosphorylationGO:00423251470.022
regulation of organ morphogenesisGO:2000027780.022
regulation of phosphate metabolic processGO:00192202100.022
regulation of nervous system developmentGO:00519602480.022
lateral inhibitionGO:00463312060.022
carbohydrate derivative biosynthetic processGO:1901137850.022
adult behaviorGO:00305341370.022
regulation of immune system processGO:00026821760.022
Mouse
dendrite developmentGO:00163582040.022
dorsal closureGO:0007391790.022
vesicle mediated transportGO:00161923810.021
spermatogenesisGO:00072832000.021
organonitrogen compound metabolic processGO:19015643180.021
renal tubule morphogenesisGO:0061333440.021
segmentationGO:00352822070.021
embryonic hindgut morphogenesisGO:0048619480.021
epithelial cell differentiationGO:00308553220.021
mesenchymal cell differentiationGO:004876210.021
imaginal disc derived wing vein specificationGO:0007474480.021
gastrulationGO:0007369700.021
nucleobase containing small molecule metabolic processGO:00550861740.020
cellular catabolic processGO:00442483720.020
deathGO:00162652840.020
regulation of molecular functionGO:00650092170.020
cell fate specificationGO:0001708710.020
positive regulation of cellular amine metabolic processGO:003324000.020
leg disc developmentGO:0035218920.020
eye photoreceptor cell developmentGO:0042462810.020
organonitrogen compound biosynthetic processGO:19015661170.020
single organism biosynthetic processGO:00447112060.020
negative regulation of cellular component organizationGO:00511291080.019
axis specificationGO:00097981670.019
regulation of gene expression epigeneticGO:00400291280.018
renal system developmentGO:0072001720.018
columnar cuboidal epithelial cell differentiationGO:00020652560.018
morphogenesis of a branching structureGO:0001763450.018
positive regulation of catalytic activityGO:00430851180.018
enzyme linked receptor protein signaling pathwayGO:00071671790.018
photoreceptor cell developmentGO:0042461960.018
cellular ketone metabolic processGO:0042180240.018
regulation of immune responseGO:00507761180.018
Mouse
anterior posterior axis specification embryoGO:00085951030.018
heterocycle catabolic processGO:00467001660.018
positive regulation of cellular component organizationGO:00511301560.018
blastoderm segmentationGO:00073501590.018
malpighian tubule morphogenesisGO:0007443440.018
regulation of cell cycleGO:00517262910.018
regulation of notch signaling pathwayGO:00085931000.017
regulation of cellular amine metabolic processGO:003323830.017
muscle structure developmentGO:00610612240.017
Mouse
adult locomotory behaviorGO:0008344760.017
single organism cellular localizationGO:19025801800.017
kidney epithelium developmentGO:007207330.017
purine ribonucleoside triphosphate metabolic processGO:00092051190.017
dna metabolic processGO:00062592270.017
actin filament organizationGO:00070151260.017
protein localization to nucleusGO:0034504550.016
cellular amino acid metabolic processGO:0006520610.016
columnar cuboidal epithelial cell developmentGO:00020662490.016
cardiovascular system developmentGO:0072358820.016
Zebrafish
establishment of planar polarityGO:0001736870.016
oxoacid metabolic processGO:00434361030.016
regulation of establishment of protein localizationGO:0070201610.016
cell adhesionGO:00071551360.016
carbohydrate derivative catabolic processGO:19011361180.016
tripartite regional subdivisionGO:00073511030.016
positive regulation of cell deathGO:0010942690.016
regulation of catabolic processGO:00098941700.016
regulation of cell fate specificationGO:0042659270.016
regulation of response to biotic stimulusGO:0002831630.016
urogenital system developmentGO:0001655720.016
positive regulation of molecular functionGO:00440931360.016
actin filament based processGO:00300292200.016
regulation of gene silencingGO:0060968630.016
response to biotic stimulusGO:00096072940.015
cellular nitrogen compound catabolic processGO:00442701650.015
establishment of tissue polarityGO:0007164870.015
programmed cell deathGO:00125012570.015
apoptotic processGO:00069151590.015
guanosine containing compound catabolic processGO:1901069740.015
cell cell signaling involved in cell fate commitmentGO:00451682100.015
retina development in camera type eyeGO:006004140.015
nephron tubule morphogenesisGO:007207830.015
mesenchymal cell developmentGO:001403110.015
endocytosisGO:00068973100.015
homeostatic processGO:00425921990.015
protein secretionGO:0009306450.015
regulation of protein modification processGO:00313991120.014
dorsal ventral pattern formationGO:00099531330.014
neuron projection guidanceGO:00974852410.014
response to external biotic stimulusGO:00432072930.014
neuron fate commitmentGO:0048663500.014
Fly
positive regulation of phosphate metabolic processGO:00459371390.014
regulation of transportGO:00510491810.014
nucleoside metabolic processGO:00091161270.014
positive regulation of multicellular organismal processGO:00512401430.014
Mouse
response to organophosphorusGO:004668320.014
aromatic compound catabolic processGO:00194391660.014
head involutionGO:0008258350.014
oocyte developmentGO:00485991240.014
stem cell developmentGO:0048864790.014
proteolysisGO:00065081920.014
response to lipopolysaccharideGO:003249640.014
nephron tubule developmentGO:007208030.014
cell junction organizationGO:0034330570.014
cellular protein catabolic processGO:0044257830.014
amine metabolic processGO:0009308120.014
nephron epithelium developmentGO:007200930.014
axon guidanceGO:00074112330.014
purine ribonucleotide metabolic processGO:00091501450.014
branching involved in open tracheal system developmentGO:0060446450.014
regulation of response to stressGO:00801342000.014
kidney morphogenesisGO:006099330.014
cell fate determinationGO:0001709910.013
sensory perceptionGO:00076001960.013
regulation of protein localizationGO:0032880760.013
rna processingGO:00063961470.013
hematopoietic or lymphoid organ developmentGO:0048534570.013
Mouse
regulation of cell morphogenesis involved in differentiationGO:0010769610.013
mapk cascadeGO:00001651070.013
autophagyGO:00069141080.013
cellular macromolecule catabolic processGO:00442651360.013
posttranscriptional regulation of gene expressionGO:00106081450.013
sensory perception of mechanical stimulusGO:0050954720.013
protein localizationGO:00081042840.013
cellular component assembly involved in morphogenesisGO:00109271510.013
regulation of growthGO:00400082330.013
Mouse
axonogenesisGO:00074092900.013
peptidyl amino acid modificationGO:00181931050.013
single organism membrane organizationGO:0044802930.013
eye antennal disc developmentGO:0035214600.013
phototaxisGO:0042331210.013
synaptic growth at neuromuscular junctionGO:00511241190.013
regulation of cell developmentGO:00602842150.013
regulation of mapk cascadeGO:0043408920.013
detection of external stimulusGO:0009581660.013
regulation of translationGO:0006417560.013
positive regulation of intracellular signal transductionGO:19025331160.013
hindgut developmentGO:0061525580.013
purine nucleotide catabolic processGO:00061951090.013
axon developmentGO:00615642970.012
regulation of protein metabolic processGO:00512462560.012
erbb signaling pathwayGO:0038127580.012
ribonucleoside triphosphate catabolic processGO:00092031080.012
cellular response to chemical stimulusGO:00708871990.012
developmental pigmentationGO:0048066680.012
regulation of catalytic activityGO:00507901850.012
guanosine containing compound metabolic processGO:1901068740.012
intraspecies interaction between organismsGO:005170340.012
negative regulation of cell cycle processGO:00109481090.012
neuromuscular junction developmentGO:00075281490.012
immune response activating signal transductionGO:000275720.012
organic substance catabolic processGO:19015753080.012
nephron morphogenesisGO:007202830.012
regulation of epithelial cell differentiationGO:003085640.012
regulation of mrna processingGO:0050684710.012
regulation of i kappab kinase nf kappab signalingGO:004312220.012
negative regulation of wnt signaling pathwayGO:0030178280.012
mrna metabolic processGO:00160711240.012
organic cyclic compound catabolic processGO:19013611680.012
ribose phosphate metabolic processGO:00196931450.012
nephron epithelium morphogenesisGO:007208830.012
purine nucleoside triphosphate catabolic processGO:00091461080.012
anatomical structure homeostasisGO:0060249970.012
positive regulation of developmental processGO:00510941430.012
Mouse
regulation of intracellular protein transportGO:0033157460.012
eye pigmentationGO:0048069430.012
localization of cellGO:00516742570.012
cell growthGO:00160491080.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.012
developmental growthGO:00485892800.012
Mouse
cellular response to biotic stimulusGO:007121640.012
positive regulation of cell migrationGO:003033520.012
hippo signalingGO:0035329200.012
regulation of programmed cell deathGO:00430671520.012
detection of abiotic stimulusGO:0009582660.012
notch signaling pathwayGO:00072191200.012
single organism cell adhesionGO:0098602470.012
positive regulation of protein modification processGO:0031401580.011
regulation of mitotic cell cycleGO:00073461900.011
telencephalon developmentGO:002153720.011
regulation of organelle organizationGO:00330431960.011
regulation of cytoskeleton organizationGO:0051493890.011
peptidyl lysine modificationGO:0018205570.011
nucleotide metabolic processGO:00091171610.011
mrna processingGO:00063971040.011
wing disc pattern formationGO:0035222660.011
camera type eye morphogenesisGO:004859320.011
dna endoreduplicationGO:0042023220.011
cell migrationGO:00164772380.011
developmental growth involved in morphogenesisGO:0060560650.011
regulation of mrna splicing via spliceosomeGO:0048024640.011
single organism catabolic processGO:00447122280.011
developmental maturationGO:00217001720.011
signal transduction by phosphorylationGO:00230141070.011
response to hexoseGO:000974630.011
activation of innate immune responseGO:000221840.011
cuticle developmentGO:0042335860.011
photoreceptor cell fate commitmentGO:0046552410.011
positive regulation of peptidyl tyrosine phosphorylationGO:005073140.011
organic substance transportGO:00717022570.011
regulation of cellular catabolic processGO:00313291570.011
compound eye photoreceptor developmentGO:0042051780.011
organelle fissionGO:00482853400.011
regulation of cellular protein metabolic processGO:00322682430.011
positive regulation of nucleotide metabolic processGO:0045981550.011
response to oxygen containing compoundGO:19017002000.011
response to endogenous stimulusGO:00097191190.011
developmental inductionGO:003112830.011
regulation of heart morphogenesisGO:200082630.011
protein transportGO:00150311550.011
ribonucleoside catabolic processGO:00424541120.011
organophosphate metabolic processGO:00196371950.011
negative regulation of mitotic cell cycle phase transitionGO:19019911030.011
substrate adhesion dependent cell spreadingGO:003444620.011
multicellular organismal homeostasisGO:0048871410.011
protein kinase b signalingGO:004349110.011
organic acid metabolic processGO:00060821030.010
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377730.010
response to organic cyclic compoundGO:0014070890.010
adherens junction organizationGO:0034332270.010
leg disc morphogenesisGO:0007478800.010
regulation of gtpase activityGO:0043087440.010
regulation of cellular localizationGO:00603411360.010
cellular macromolecule localizationGO:00707272200.010
purine nucleotide metabolic processGO:00061631460.010
regulation of ras protein signal transductionGO:0046578930.010
hematopoietic progenitor cell differentiationGO:000224410.010
instar larval developmentGO:0002168550.010
positive regulation of signal transductionGO:00099672230.010
imaginal disc derived leg morphogenesisGO:0007480800.010
phagocytosisGO:00069092150.010
single organismal cell cell adhesionGO:0016337450.010
regulation of epithelial cell proliferationGO:005067840.010
muscle organ developmentGO:00075171270.010
Mouse
response to nutrient levelsGO:00316671140.010
g protein coupled receptor signaling pathwayGO:00071861360.010
regulation of cell shapeGO:00083601130.010
organ growthGO:0035265560.010
Mouse
convergent extensionGO:006002620.010

H2.0 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.024
musculoskeletal system diseaseDOID:1700.018
bone diseaseDOID:008000100.014
connective tissue diseaseDOID:6500.014
nervous system diseaseDOID:86300.011
sensory system diseaseDOID:005015500.010