Drosophila melanogaster

15 known processes

l(2)37Cb (Dmel_CG10689)

lethal (2) 37Cb

(Aliases: Cb,CG10689,cg10689,Dmel\CG10689,l(2)E104)

l(2)37Cb biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of nucleobase containing compound metabolic processGO:00459353320.787
dna metabolic processGO:00062592270.593
embryo development ending in birth or egg hatchingGO:00097921520.354
Worm
pigmentationGO:0043473750.224
positive regulation of transcription dna templatedGO:00458932660.223
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377730.190
Yeast
positive regulation of macromolecule metabolic processGO:00106044050.187
positive regulation of nitrogen compound metabolic processGO:00511733540.176
cellular macromolecular complex assemblyGO:00346221530.172
Yeast
regionalizationGO:00030024160.161
chromosome organizationGO:00512763600.153
protein acetylationGO:0006473390.136
mrna processingGO:00063971040.133
Yeast
rna processingGO:00063961470.131
Yeast
ncrna 3 end processingGO:0043628170.131
regulation of dna metabolic processGO:0051052340.124
mrna metabolic processGO:00160711240.123
Yeast
larval developmentGO:00021641040.120
Worm
positive regulation of biosynthetic processGO:00098913160.119
internal protein amino acid acetylationGO:0006475380.117
peptidyl lysine modificationGO:0018205570.116
positive regulation of cellular biosynthetic processGO:00313283160.115
regulation of programmed cell deathGO:00430671520.114
cell proliferationGO:00082832990.111
Worm
endocytosisGO:00068973100.107
positive regulation of nucleic acid templated transcriptionGO:19035082660.104
snrna 3 end processingGO:0034472140.103
positive regulation of gene expressionGO:00106282900.102
cellular protein modification processGO:00064644380.099
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.095
protein dna complex subunit organizationGO:0071824860.093
developmental pigmentationGO:0048066680.092
nucleobase containing compound catabolic processGO:00346551650.090
Yeast
small molecule metabolic processGO:00442813050.089
Yeast
deathGO:00162652840.085
organonitrogen compound metabolic processGO:19015643180.085
Yeast
snrna metabolic processGO:0016073140.083
protein acylationGO:0043543420.082
positive regulation of rna metabolic processGO:00512542710.080
regulation of dna templated transcription elongationGO:0032784170.078
rna splicing via transesterification reactionsGO:0000375730.078
Yeast
apoptotic processGO:00069151590.076
regulation of organelle organizationGO:00330431960.072
Worm
immune system processGO:00023763470.071
macromolecular complex assemblyGO:00650032560.070
Yeast
cellular catabolic processGO:00442483720.067
Yeast
meiotic cell cycleGO:00513211710.067
Worm
negative regulation of gene expressionGO:00106293870.065
regulation of cell cycleGO:00517262910.065
Worm
positive regulation of molecular functionGO:00440931360.064
protein dna complex assemblyGO:0065004630.063
embryonic morphogenesisGO:00485982060.062
Zebrafish Worm
cellular nitrogen compound catabolic processGO:00442701650.059
Yeast
meiotic nuclear divisionGO:00071261510.058
Worm
heterocycle catabolic processGO:00467001660.058
Yeast
histone modificationGO:00165701060.053
chromatin modificationGO:00165681470.053
exocrine system developmentGO:00352721620.052
programmed cell deathGO:00125012570.052
positive regulation of rna biosynthetic processGO:19026802660.052
chromatin organizationGO:00063252070.051
dendrite morphogenesisGO:00488131990.051
ncrna metabolic processGO:0034660430.051
Yeast
organophosphate metabolic processGO:00196371950.051
Yeast
carbohydrate derivative metabolic processGO:19011352170.049
Yeast
response to other organismGO:00517072930.049
cell maturationGO:00484691440.048
aromatic compound catabolic processGO:00194391660.048
Yeast
negative regulation of cellular metabolic processGO:00313243820.047
dna replicationGO:0006260480.047
regulation of protein metabolic processGO:00512462560.046
positive regulation of macromolecule biosynthetic processGO:00105572830.044
stem cell maintenanceGO:0019827670.044
gene silencingGO:00164581380.044
snrna processingGO:0016180140.044
nucleotide metabolic processGO:00091171610.043
Yeast
internal peptidyl lysine acetylationGO:0018393380.043
response to abiotic stimulusGO:00096283410.042
imaginal disc derived wing morphogenesisGO:00074763370.041
intracellular signal transductionGO:00355563000.040
negative regulation of rna metabolic processGO:00512532510.039
single organism biosynthetic processGO:00447112060.039
rna 3 end processingGO:0031123450.039
organic acid metabolic processGO:00060821030.038
positive regulation of cellular component organizationGO:00511301560.037
transcription from rna polymerase ii promoterGO:00063663680.037
protein modification processGO:00362114380.036
response to external biotic stimulusGO:00432072930.035
regulation of mrna splicing via spliceosomeGO:0048024640.034
catabolic processGO:00090564090.034
Yeast
regulation of mitotic cell cycle phase transitionGO:19019901300.034
cell deathGO:00082192790.034
cellular response to dna damage stimulusGO:00069742230.033
regulation of molecular functionGO:00650092170.033
positive regulation of cell communicationGO:00106472500.033
axon developmentGO:00615642970.033
organelle assemblyGO:00709251980.033
histone acetylationGO:0016573380.032
positive regulation of catalytic activityGO:00430851180.032
negative regulation of nitrogen compound metabolic processGO:00511722650.032
rna splicingGO:0008380830.032
Yeast
peptidyl lysine acetylationGO:0018394390.031
response to bacteriumGO:00096171980.031
brain developmentGO:00074201200.031
cellular amino acid metabolic processGO:0006520610.031
response to lipopolysaccharideGO:003249640.031
vesicle mediated transportGO:00161923810.030
regulation of mrna processingGO:0050684710.030
homeostatic processGO:00425921990.030
carboxylic acid metabolic processGO:0019752920.029
positive regulation of cellular protein metabolic processGO:00322701180.029
central nervous system developmentGO:00074172010.029
taxisGO:00423303040.029
response to biotic stimulusGO:00096072940.028
nucleoside phosphate metabolic processGO:00067531620.028
Yeast
imaginal disc derived appendage morphogenesisGO:00351143950.028
oxoacid metabolic processGO:00434361030.028
regulation of apoptotic processGO:00429811300.028
peptidyl amino acid modificationGO:00181931050.027
organic substance catabolic processGO:19015753080.027
Yeast
rna transportGO:0050658460.027
dna packagingGO:0006323910.027
rna localizationGO:00064031150.026
dna repairGO:0006281540.026
regulation of chromosome organizationGO:0033044640.026
antimicrobial humoral responseGO:0019730990.025
intracellular transportGO:00469072280.025
innate immune responseGO:00450871440.025
purine ribonucleotide metabolic processGO:00091501450.025
Yeast
negative regulation of macromolecule biosynthetic processGO:00105582700.025
phagocytosisGO:00069092150.025
glycosyl compound metabolic processGO:19016571270.025
Yeast
dna templated transcription elongationGO:0006354180.025
neuron projection guidanceGO:00974852410.024
imaginal disc derived appendage developmentGO:00487373990.024
tube morphogenesisGO:00352391910.024
Zebrafish
immune responseGO:00069552460.024
positive regulation of hydrolase activityGO:0051345780.024
regulation of anatomical structure morphogenesisGO:00226032420.024
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.023
post embryonic appendage morphogenesisGO:00351203850.023
regulation of intracellular signal transductionGO:19025312360.023
regulation of developmental pigmentationGO:0048070240.023
axon guidanceGO:00074112330.023
hindbrain developmentGO:003090220.022
response to temperature stimulusGO:00092661060.022
rna polyadenylationGO:0043631120.022
regulation of small gtpase mediated signal transductionGO:0051056930.022
histone h2a acetylationGO:004396810.022
regulation of transcription elongation from rna polymerase ii promoterGO:0034243150.022
organic cyclic compound catabolic processGO:19013611680.022
Yeast
chromatin assembly or disassemblyGO:0006333520.022
axonogenesisGO:00074092900.022
regulation of hydrolase activityGO:0051336970.021
positive regulation of protein modification processGO:0031401580.021
small gtpase mediated signal transductionGO:0007264880.021
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.021
dendrite developmentGO:00163582040.021
gene silencing by rnaGO:0031047570.020
ribonucleoside monophosphate metabolic processGO:0009161510.020
Yeast
response to oxygen containing compoundGO:19017002000.020
proteolysisGO:00065081920.020
defense responseGO:00069523000.020
regulation of rna splicingGO:0043484690.020
purine nucleoside metabolic processGO:00422781270.019
Yeast
cellular macromolecule catabolic processGO:00442651360.019
humoral immune responseGO:00069591170.019
negative regulation of gene expression epigeneticGO:0045814770.018
response to lipidGO:0033993380.018
regulation of gene silencingGO:0060968630.018
regulation of cell divisionGO:0051302720.018
Worm
chromatin silencingGO:0006342760.018
establishment of localization in cellGO:00516494020.018
single organism catabolic processGO:00447122280.017
Yeast
purine nucleoside monophosphate metabolic processGO:0009126500.017
Yeast
dna conformation changeGO:00711031050.017
regulation of immune responseGO:00507761180.017
nucleotide catabolic processGO:00091661090.017
Yeast
purine nucleoside triphosphate metabolic processGO:00091441190.017
Yeast
ribose phosphate metabolic processGO:00196931450.016
Yeast
regulation of cell morphogenesisGO:00226041630.016
ribonucleotide metabolic processGO:00092591450.016
Yeast
ribonucleoside monophosphate catabolic processGO:0009158390.016
Yeast
regulation of transcription from rna polymerase ii promoterGO:00063573780.016
positive regulation of signalingGO:00230562430.016
muscle organ developmentGO:00075171270.016
transcription initiation from rna polymerase ii promoterGO:0006367250.016
appendage morphogenesisGO:00351073970.015
response to organic substanceGO:00100332840.015
positive regulation of cellular amino acid metabolic processGO:004576400.015
dna dependent dna replicationGO:0006261170.015
purine ribonucleoside metabolic processGO:00461281270.015
Yeast
purine containing compound metabolic processGO:00725211550.015
Yeast
molting cycle processGO:0022404290.015
cellular response to organic substanceGO:00713101320.015
cytoskeleton dependent intracellular transportGO:0030705440.015
rna interferenceGO:0016246270.014
regulation of cell deathGO:00109411730.014
reproductive system developmentGO:0061458740.014
Worm
cell cycle dna replicationGO:0044786230.014
localization of cellGO:00516742570.014
sensory organ morphogenesisGO:00905962600.014
morphogenesis of an epitheliumGO:00020092760.014
dna biosynthetic processGO:0071897240.014
eye developmentGO:00016543230.013
posttranscriptional gene silencingGO:0016441460.013
covalent chromatin modificationGO:00165691060.013
regulation of catalytic activityGO:00507901850.013
cell cell signaling involved in cell fate commitmentGO:00451682100.012
positive regulation of response to stimulusGO:00485843230.012
atp metabolic processGO:0046034490.012
Yeast
purine nucleotide catabolic processGO:00061951090.012
Yeast
nucleobase containing small molecule metabolic processGO:00550861740.012
Yeast
negative regulation of nucleobase containing compound metabolic processGO:00459342610.012
phosphorylationGO:00163102940.012
negative regulation of developmental processGO:00510932010.012
regulation of mrna metabolic processGO:1903311720.012
heart developmentGO:0007507820.012
chemotaxisGO:00069352490.012
negative regulation of cell communicationGO:00106482230.012
regulation of cellular amino acid metabolic processGO:000652100.012
single organism intracellular transportGO:19025822070.012
camera type eye developmentGO:004301040.012
defense response to bacteriumGO:00427421780.011
muscle structure developmentGO:00610612240.011
regulation of mitotic cell cycleGO:00073461900.011
gland developmentGO:00487321910.011
body morphogenesisGO:001017120.011
Worm
regulation of neurogenesisGO:00507671580.011
mrna polyadenylationGO:0006378110.011
salivary gland morphogenesisGO:00074351450.011
cellular response to chemical stimulusGO:00708871990.011
cytoplasmic transportGO:00164821300.011
negative regulation of cell cycle processGO:00109481090.011
amine metabolic processGO:0009308120.011
cellular protein complex assemblyGO:0043623710.011
stem cell differentiationGO:00488631170.011
mitotic sister chromatid segregationGO:0000070870.011
nucleoside monophosphate catabolic processGO:0009125390.011
Yeast
negative regulation of rna biosynthetic processGO:19026792400.011
response to heatGO:0009408630.011
sex differentiationGO:0007548810.010
Worm
alternative mrna splicing via spliceosomeGO:0000380600.010
regulation of gene expression epigeneticGO:00400291280.010
negative regulation of cellular biosynthetic processGO:00313272770.010
oocyte differentiationGO:00099941450.010
positive regulation of intracellular signal transductionGO:19025331160.010
tube developmentGO:00352952440.010
Zebrafish
positive regulation of protein metabolic processGO:00512471280.010
oocyte developmentGO:00485991240.010
telomere organizationGO:0032200210.010
carbohydrate derivative biosynthetic processGO:1901137850.010

l(2)37Cb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.020
nervous system diseaseDOID:86300.011