IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

CG14650 (Dmel_CG14650)

CG14650 gene product from transcript CG14650-RA

(Aliases: Dmel\CG14650)

Entrez: 40566
FLYBASE: FBgn0037252
UniProtKB: Q9VN28

Process Predictions
Disease Predictions

CG14650 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
cellular protein modification process	GO:0006464	438	0.150
regulation of intracellular signal transduction	GO:1902531	236	0.124
intracellular signal transduction	GO:0035556	300	0.087
positive regulation of cell communication	GO:0010647	250	0.087
positive regulation of signaling	GO:0023056	243	0.085
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.079
positive regulation of macromolecule metabolic process	GO:0010604	405	0.073
positive regulation of signal transduction	GO:0009967	223	0.070
regulation of anatomical structure size	GO:0090066	163	0.067
ras protein signal transduction	GO:0007265	88	0.067
organonitrogen compound metabolic process	GO:1901564	318	0.067
protein modification process	GO:0036211	438	0.058
regulation of ras protein signal transduction	GO:0046578	93	0.057
nucleotide metabolic process	GO:0009117	161	0.053
cell proliferation	GO:0008283	299	0.052
defense response	GO:0006952	300	0.051
ribose phosphate metabolic process	GO:0019693	145	0.050
positive regulation of multicellular organismal process	GO:0051240	143	0.048
neurological system process	GO:0050877	358	0.047
regulation of phosphorus metabolic process	GO:0051174	210	0.046
transcription from rna polymerase ii promoter	GO:0006366	368	0.045
cellular protein localization	GO:0034613	160	0.044
positive regulation of response to stimulus	GO:0048584	323	0.043
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.042
small gtpase mediated signal transduction	GO:0007264	88	0.041
learning or memory	GO:0007611	141	0.040
regulation of phosphate metabolic process	GO:0019220	210	0.040
response to organic substance	GO:0010033	284	0.040
aging	GO:0007568	143	0.040
cell migration	GO:0016477	238	0.038
regulation of neuron projection development	GO:0010975	69	0.035
positive regulation of phosphorus metabolic process	GO:0010562	139	0.035
regulation of cellular component biogenesis	GO:0044087	201	0.035
establishment of localization in cell	GO:0051649	402	0.035
positive regulation of phosphate metabolic process	GO:0045937	139	0.034
protein modification by small protein conjugation or removal	GO:0070647	106	0.034
body morphogenesis	GO:0010171	2	0.034
gtp metabolic process	GO:0046039	72	0.033
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	65	0.033
development of primary sexual characteristics	GO:0045137	50	0.032
purine nucleotide metabolic process	GO:0006163	146	0.032
positive regulation of cell motility	GO:2000147	3	0.032
cognition	GO:0050890	141	0.032
forebrain development	GO:0030900	2	0.031
regulation of purine nucleotide catabolic process	GO:0033121	48	0.029
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.029
glycosyl compound catabolic process	GO:1901658	112	0.028
nucleobase containing small molecule metabolic process	GO:0055086	174	0.028
establishment or maintenance of cell polarity	GO:0007163	167	0.028
embryonic hemopoiesis	GO:0035162	26	0.027
regulation of molecular function	GO:0065009	217	0.027
tissue morphogenesis	GO:0048729	297	0.027
purine nucleotide catabolic process	GO:0006195	109	0.027
telencephalon development	GO:0021537	2	0.027
glycosyl compound metabolic process	GO:1901657	127	0.026
multicellular organismal aging	GO:0010259	140	0.026
appendage morphogenesis	GO:0035107	397	0.026
wing disc morphogenesis	GO:0007472	344	0.026
eye morphogenesis	GO:0048592	260	0.025
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.025
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.025
carbohydrate derivative catabolic process	GO:1901136	118	0.025
hindbrain development	GO:0030902	2	0.025
endocytosis	GO:0006897	310	0.025
developmental growth	GO:0048589	280	0.024
regulation of catalytic activity	GO:0050790	185	0.024
purine ribonucleoside catabolic process	GO:0046130	112	0.024
intracellular transport	GO:0046907	228	0.024
chromatin organization	GO:0006325	207	0.024
cellular macromolecule localization	GO:0070727	220	0.023
purine ribonucleotide metabolic process	GO:0009150	145	0.023
nucleoside phosphate catabolic process	GO:1901292	110	0.023
regulation of growth	GO:0040008	233	0.023
cell adhesion	GO:0007155	136	0.023
regulation of developmental growth	GO:0048638	174	0.022
regulation of ras gtpase activity	GO:0032318	38	0.022
regulation of rab protein signal transduction	GO:0032483	7	0.022
cell motility	GO:0048870	251	0.022
cellular response to organic substance	GO:0071310	132	0.022
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.022
ribonucleotide catabolic process	GO:0009261	109	0.021
regulation of insulin like growth factor receptor signaling pathway	GO:0043567	3	0.021
sensory organ morphogenesis	GO:0090596	260	0.021
localization of cell	GO:0051674	257	0.021
central nervous system development	GO:0007417	201	0.021
exocrine system development	GO:0035272	162	0.021
defense response to other organism	GO:0098542	225	0.021
nucleoside triphosphate catabolic process	GO:0009143	108	0.021
carbohydrate derivative metabolic process	GO:1901135	217	0.021
regulation of gtpase activity	GO:0043087	44	0.021
compound eye development	GO:0048749	307	0.021
determination of adult lifespan	GO:0008340	137	0.021
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.020
memory	GO:0007613	94	0.020
guanosine containing compound metabolic process	GO:1901068	74	0.020
positive regulation of cellular catabolic process	GO:0031331	95	0.020
appendage development	GO:0048736	401	0.020
inositol lipid mediated signaling	GO:0048017	4	0.020
cytoplasmic transport	GO:0016482	130	0.020
purine nucleoside catabolic process	GO:0006152	112	0.020
phosphorylation	GO:0016310	294	0.020
regulation of notch signaling pathway	GO:0008593	100	0.020
response to wounding	GO:0009611	94	0.020
eye development	GO:0001654	323	0.020
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.020
positive regulation of protein modification process	GO:0031401	58	0.019
cellular response to chemical stimulus	GO:0070887	199	0.019
purine ribonucleotide catabolic process	GO:0009154	109	0.019
positive regulation of phosphorylation	GO:0042327	87	0.019
regulation of phosphorylation	GO:0042325	147	0.019
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.019
regulation of response to stress	GO:0080134	200	0.019
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.019
response to oxygen containing compound	GO:1901700	200	0.019
membrane budding	GO:0006900	4	0.019
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.019
dna templated transcription elongation	GO:0006354	18	0.019
regulation of hydrolase activity	GO:0051336	97	0.018
positive regulation of gene expression	GO:0010628	290	0.018
response to endogenous stimulus	GO:0009719	119	0.018
positive regulation of developmental process	GO:0051094	143	0.018
cell death	GO:0008219	279	0.018
protein complex biogenesis	GO:0070271	201	0.018
organic substance transport	GO:0071702	257	0.018
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.018
regulation of cell proliferation	GO:0042127	163	0.018
chemosensory behavior	GO:0007635	106	0.018
response to biotic stimulus	GO:0009607	294	0.018
positive regulation of intracellular signal transduction	GO:1902533	116	0.018
organelle inheritance	GO:0048308	2	0.017
dephosphorylation	GO:0016311	51	0.017
growth	GO:0040007	359	0.017
nucleoside phosphate metabolic process	GO:0006753	162	0.017
notch signaling pathway	GO:0007219	120	0.017
rho protein signal transduction	GO:0007266	14	0.017
dendrite development	GO:0016358	204	0.017
gtp catabolic process	GO:0006184	72	0.017
vesicle mediated transport	GO:0016192	381	0.017
regulation of cell morphogenesis	GO:0022604	163	0.016
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.016
protein localization	GO:0008104	284	0.016
purine nucleoside metabolic process	GO:0042278	127	0.016
aromatic compound catabolic process	GO:0019439	166	0.016
ribonucleotide metabolic process	GO:0009259	145	0.016
regionalization	GO:0003002	416	0.016
defense response to bacterium	GO:0042742	178	0.016
endomembrane system organization	GO:0010256	119	0.016
compound eye morphogenesis	GO:0001745	249	0.016
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.016
positive regulation of gtp catabolic process	GO:0033126	43	0.015
response to bacterium	GO:0009617	198	0.015
gland morphogenesis	GO:0022612	145	0.015
organophosphate metabolic process	GO:0019637	195	0.015
single organism behavior	GO:0044708	391	0.015
peptidyl amino acid modification	GO:0018193	105	0.015
dendrite morphogenesis	GO:0048813	199	0.015
positive regulation of growth	GO:0045927	75	0.015
rna splicing	GO:0008380	83	0.015
regulation of nucleotide metabolic process	GO:0006140	62	0.015
regulation of protein modification process	GO:0031399	112	0.015
immune system process	GO:0002376	347	0.015
nucleoside metabolic process	GO:0009116	127	0.014
regulation of protein metabolic process	GO:0051246	256	0.014
carbohydrate derivative biosynthetic process	GO:1901137	85	0.014
dna conformation change	GO:0071103	105	0.014
positive regulation of nucleotide catabolic process	GO:0030813	46	0.014
regulation of purine nucleotide metabolic process	GO:1900542	62	0.014
regulation of cell substrate adhesion	GO:0010810	2	0.014
response to other organism	GO:0051707	293	0.014
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.014
regulation of gtp catabolic process	GO:0033124	44	0.014
nucleoside catabolic process	GO:0009164	112	0.014
regulation of cell motility	GO:2000145	23	0.013
cell maturation	GO:0048469	144	0.013
positive regulation of hydrolase activity	GO:0051345	78	0.013
mitotic nuclear division	GO:0007067	213	0.013
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.013
axonogenesis	GO:0007409	290	0.013
regulation of anatomical structure morphogenesis	GO:0022603	242	0.013
purine containing compound metabolic process	GO:0072521	155	0.013
positive regulation of nucleoside metabolic process	GO:0045979	47	0.013
positive regulation of mapk cascade	GO:0043410	63	0.013
response to organic cyclic compound	GO:0014070	89	0.013
protein phosphorylation	GO:0006468	169	0.013
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.013
small molecule metabolic process	GO:0044281	305	0.012
regulation of cell development	GO:0060284	215	0.012
dna metabolic process	GO:0006259	227	0.012
multicellular organism growth	GO:0035264	46	0.012
regulation of transport	GO:0051049	181	0.012
positive regulation of catabolic process	GO:0009896	105	0.012
gland development	GO:0048732	191	0.012
regulation of histone deacetylation	GO:0031063	2	0.012
nucleoside triphosphate metabolic process	GO:0009141	120	0.012
regulation of localization	GO:0032879	275	0.012
positive regulation of cellular component organization	GO:0051130	156	0.012
brain development	GO:0007420	120	0.012
regulation of cellular ketone metabolic process	GO:0010565	3	0.012
chromatin assembly or disassembly	GO:0006333	52	0.012
negative regulation of cell differentiation	GO:0045596	143	0.012
purine containing compound catabolic process	GO:0072523	112	0.012
single organism cellular localization	GO:1902580	180	0.012
protein localization to organelle	GO:0033365	82	0.012
organophosphate catabolic process	GO:0046434	112	0.012
protein transport	GO:0015031	155	0.012
negative regulation of response to stimulus	GO:0048585	258	0.012
regulation of cell cycle	GO:0051726	291	0.012
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.012
negative regulation of molecular function	GO:0044092	51	0.011
negative regulation of programmed cell death	GO:0043069	72	0.011
positive regulation of purine nucleotide catabolic process	GO:0033123	46	0.011
positive regulation of cellular biosynthetic process	GO:0031328	316	0.011
regulation of programmed cell death	GO:0043067	152	0.011
regulation of nervous system development	GO:0051960	248	0.011
rna splicing via transesterification reactions	GO:0000375	73	0.011
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.011
positive regulation of transcription dna templated	GO:0045893	266	0.011
regulation of cellular protein metabolic process	GO:0032268	243	0.011
negative regulation of multicellular organismal process	GO:0051241	142	0.011
proteolysis	GO:0006508	192	0.011
head development	GO:0060322	135	0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	38	0.011
photoreceptor cell development	GO:0042461	96	0.011
multi multicellular organism process	GO:0044706	123	0.011
cellular homeostasis	GO:0019725	80	0.010
positive regulation of stem cell differentiation	GO:2000738	3	0.010
regulation of cellular catabolic process	GO:0031329	157	0.010
olfactory behavior	GO:0042048	97	0.010
chromatin modification	GO:0016568	147	0.010
organonitrogen compound catabolic process	GO:1901565	128	0.010
periodic partitioning	GO:0007365	29	0.010
open tracheal system development	GO:0007424	204	0.010
positive regulation of cell differentiation	GO:0045597	64	0.010
regulation of nucleotide catabolic process	GO:0030811	48	0.010
mitotic cell cycle phase transition	GO:0044772	138	0.010
positive regulation of developmental growth	GO:0048639	62	0.010
regulation of system process	GO:0044057	36	0.010

CG14650 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.055
disease of cellular proliferation	DOID:14566	0.027
organ system cancer	DOID:0050686	0.024
cancer	DOID:162	0.024
nervous system disease	DOID:863	0.018

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