Drosophila melanogaster

0 known processes

alpha-Est4 (Dmel_CG1082)

alpha-Esterase-4

(Aliases: alphaE4,C,aE4,DmalphaE4,Dmel\CG1082,CG1082)

alpha-Est4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
small molecule metabolic processGO:00442813050.095
Fly
response to abiotic stimulusGO:00096283410.053
Fly
vesicle mediated transportGO:00161923810.051
steroid catabolic processGO:000670610.047
response to other organismGO:00517072930.046
Fly
sensory perception of chemical stimulusGO:00076061160.046
endocytosisGO:00068973100.046
organic acid metabolic processGO:00060821030.045
imaginal disc derived appendage developmentGO:00487373990.044
Fly
wing disc morphogenesisGO:00074723440.044
Fly
imaginal disc derived appendage morphogenesisGO:00351143950.043
Fly
neurological system processGO:00508773580.043
cellular response to ethanolGO:007136140.042
chaeta developmentGO:0022416970.042
response to external biotic stimulusGO:00432072930.042
Fly
xenobiotic catabolic processGO:004217810.041
positive regulation of response to stimulusGO:00485843230.040
appendage morphogenesisGO:00351073970.040
Fly
oxoacid metabolic processGO:00434361030.040
phagocytosisGO:00069092150.040
hormone catabolic processGO:004244730.039
intracellular signal transductionGO:00355563000.039
response to nutrient levelsGO:00316671140.038
organonitrogen compound metabolic processGO:19015643180.038
Fly
negative regulation of gene expressionGO:00106293870.037
response to oxygen containing compoundGO:19017002000.037
immune responseGO:00069552460.037
post embryonic appendage morphogenesisGO:00351203850.036
Fly
lateral inhibitionGO:00463312060.036
defense responseGO:00069523000.035
Fly
response to lipopolysaccharideGO:003249640.035
estrogen metabolic processGO:000821010.035
protein modification processGO:00362114380.035
response to organic substanceGO:00100332840.035
Fly
cell cell signaling involved in cell fate commitmentGO:00451682100.034
carboxylic acid metabolic processGO:0019752920.033
cellular amino acid metabolic processGO:0006520610.032
cellular protein modification processGO:00064644380.031
response to biotic stimulusGO:00096072940.031
Fly
cellular catabolic processGO:00442483720.031
Fly
appendage developmentGO:00487364010.031
Fly
sensory perceptionGO:00076001960.029
organic hydroxy compound metabolic processGO:1901615830.029
Fly
response to radiationGO:00093141550.029
Fly
immune system processGO:00023763470.029
regulation of intracellular signal transductionGO:19025312360.029
organic substance transportGO:00717022570.029
homeostatic processGO:00425921990.028
benzene containing compound metabolic processGO:004253730.028
androgen metabolic processGO:000820910.027
organic substance catabolic processGO:19015753080.027
Fly
gland developmentGO:00487321910.027
regionalizationGO:00030024160.026
Fly
catabolic processGO:00090564090.026
Fly
cellular ketone metabolic processGO:0042180240.026
cholesterol homeostasisGO:004263230.026
phosphorylationGO:00163102940.025
positive regulation of cell communicationGO:00106472500.025
forebrain developmentGO:003090020.025
response to extracellular stimulusGO:00099911160.024
positive regulation of signalingGO:00230562430.024
ovarian follicle cell developmentGO:00307072480.023
Fly
imaginal disc derived wing morphogenesisGO:00074763370.023
Fly
defense response to bacteriumGO:00427421780.023
negative regulation of response to stimulusGO:00485852580.023
negative regulation of cellular metabolic processGO:00313243820.023
deathGO:00162652840.023
positive regulation of nitrogen compound metabolic processGO:00511733540.023
positive regulation of signal transductionGO:00099672230.023
single organism biosynthetic processGO:00447112060.022
lipid metabolic processGO:00066291210.022
single organism behaviorGO:00447083910.022
regulation of localizationGO:00328792750.022
single organism catabolic processGO:00447122280.022
Fly
polyol biosynthetic processGO:004617330.021
cell deathGO:00082192790.021
regulation of response to stressGO:00801342000.021
camera type eye developmentGO:004301040.021
body morphogenesisGO:001017120.021
regulation of cellular ketone metabolic processGO:001056530.021
l glutamate importGO:005193810.021
regulation of multicellular organismal developmentGO:20000264140.021
developmental growthGO:00485892800.021
sterol homeostasisGO:005509240.021
cellular response to chemical stimulusGO:00708871990.021
response to light stimulusGO:00094161240.020
Fly
nuclear divisionGO:00002803320.020
Fly
positive regulation of nucleobase containing compound metabolic processGO:00459353320.020
response to temperature stimulusGO:00092661060.020
amine metabolic processGO:0009308120.020
Fly
response to alcoholGO:0097305950.020
response to starvationGO:0042594970.020
organic cyclic compound catabolic processGO:19013611680.020
establishment of localization in cellGO:00516494020.020
taxisGO:00423303040.020
Fly
regulation of cellular amine metabolic processGO:003323830.020
response to ethanolGO:0045471590.020
cellular macromolecule localizationGO:00707272200.019
salivary gland developmentGO:00074311620.019
innate immune responseGO:00450871440.019
defense response to other organismGO:00985422250.019
Fly
regulation of phosphorus metabolic processGO:00511742100.019
organelle fissionGO:00482853400.019
Fly
transcription from rna polymerase ii promoterGO:00063663680.019
cellular response to organic substanceGO:00713101320.019
positive regulation of cellular biosynthetic processGO:00313283160.019
positive regulation of biosynthetic processGO:00098913160.019
salivary gland morphogenesisGO:00074351450.019
response to monosaccharideGO:003428440.019
aggressive behaviorGO:0002118630.018
aromatic compound catabolic processGO:00194391660.018
positive regulation of macromolecule metabolic processGO:00106044050.018
response to copper ionGO:004668840.018
regulation of cellular amino acid metabolic processGO:000652100.018
negative regulation of signalingGO:00230572190.018
protein localizationGO:00081042840.018
epithelial cell developmentGO:00020642740.018
Fly
actin filament based processGO:00300292200.018
regulation of phosphate metabolic processGO:00192202100.018
regulation of protein metabolic processGO:00512462560.018
proteolysisGO:00065081920.018
response to bacteriumGO:00096171980.018
response to organic cyclic compoundGO:0014070890.018
heterocycle catabolic processGO:00467001660.018
rhythmic processGO:00485111060.018
vitamin metabolic processGO:000676620.018
morphogenesis of an epitheliumGO:00020092760.018
kidney developmentGO:000182230.018
negative regulation of cell communicationGO:00106482230.018
regulation of catalytic activityGO:00507901850.018
ethanolamine containing compound metabolic processGO:004243940.018
Fly
adult behaviorGO:00305341370.017
response to endogenous stimulusGO:00097191190.017
regulation of molecular functionGO:00650092170.017
programmed cell deathGO:00125012570.017
regulation of cellular protein metabolic processGO:00322682430.017
localization of cellGO:00516742570.017
Fly
cell migrationGO:00164772380.017
Fly
chemical homeostasisGO:0048878920.017
tissue morphogenesisGO:00487292970.017
organophosphate metabolic processGO:00196371950.017
regulation of cell cycleGO:00517262910.017
negative regulation of signal transductionGO:00099682060.017
carbohydrate derivative metabolic processGO:19011352170.017
anion homeostasisGO:005508130.017
glycerolipid catabolic processGO:004650330.017
sensory perception of smellGO:0007608800.017
epithelial cell differentiationGO:00308553220.017
Fly
positive regulation of gene expressionGO:00106282900.016
negative regulation of nitrogen compound metabolic processGO:00511722650.016
synaptic transmissionGO:00072682880.016
Fly
compound eye developmentGO:00487493070.016
negative regulation of macromolecule biosynthetic processGO:00105582700.016
insecticide metabolic processGO:001714320.016
cellular amine metabolic processGO:0044106120.016
Fly
ion transportGO:00068111450.016
regulation of transcription from rna polymerase ii promoterGO:00063573780.016
secondary metabolite catabolic processGO:009048710.016
response to organophosphorusGO:004668320.016
Fly
fat soluble vitamin metabolic processGO:000677510.016
intracellular transportGO:00469072280.016
telencephalon developmentGO:002153720.016
response to glucoseGO:000974920.016
compound eye morphogenesisGO:00017452490.016
protein transportGO:00150311550.016
columnar cuboidal epithelial cell developmentGO:00020662490.015
Fly
response to woundingGO:0009611940.015
central nervous system developmentGO:00074172010.015
cell motilityGO:00488702510.015
Fly
cellular protein localizationGO:00346131600.015
positive regulation of cell migrationGO:003033520.015
positive regulation of rna biosynthetic processGO:19026802660.015
cell proliferationGO:00082832990.015
triglyceride biosynthetic processGO:001943220.015
negative regulation of cellular biosynthetic processGO:00313272770.015
regulation of cell deathGO:00109411730.015
axon developmentGO:00615642970.015
Fly
growthGO:00400073590.015
response to hexoseGO:000974630.015
negative regulation of biosynthetic processGO:00098902770.015
inter male aggressive behaviorGO:0002121600.015
dorsal ventral pattern formationGO:00099531330.015
macromolecular complex assemblyGO:00650032560.015
connective tissue developmentGO:006144830.015
acylglycerol catabolic processGO:004646430.015
positive regulation of nucleic acid templated transcriptionGO:19035082660.015
exocrine system developmentGO:00352721620.015
gland morphogenesisGO:00226121450.015
eye morphogenesisGO:00485922600.015
toxin catabolic processGO:000940710.015
regulation of cellular component biogenesisGO:00440872010.015
cellular response to dna damage stimulusGO:00069742230.015
positive regulation of cell motilityGO:200014730.014
cellular homeostasisGO:0019725800.014
developmental programmed cell deathGO:00106231380.014
regulation of cell cycle processGO:00105641810.014
medium chain fatty acid metabolic processGO:005179110.014
g protein coupled receptor signaling pathwayGO:00071861360.014
columnar cuboidal epithelial cell differentiationGO:00020652560.014
Fly
nucleoside phosphate metabolic processGO:00067531620.014
wound healingGO:0042060750.014
eye developmentGO:00016543230.014
response to nitrogen compoundGO:1901698900.014
establishment of protein localizationGO:00451841630.014
cellular component assembly involved in morphogenesisGO:00109271510.014
regulation of anatomical structure sizeGO:00900661630.014
Fly
regulation of transportGO:00510491810.014
nucleobase containing small molecule metabolic processGO:00550861740.014
protein phosphorylationGO:00064681690.014
detection of chemical stimulusGO:0009593930.014
humoral immune responseGO:00069591170.014
small gtpase mediated signal transductionGO:0007264880.014
imaginal disc pattern formationGO:0007447910.014
neuron projection guidanceGO:00974852410.014
Fly
single organism intracellular transportGO:19025822070.014
single organism carbohydrate metabolic processGO:0044723720.014
neuropeptide signaling pathwayGO:0007218450.014
cellular response to molecule of bacterial originGO:007121930.014
cellular nitrogen compound catabolic processGO:00442701650.014
chromosome organizationGO:00512763600.014
negative regulation of developmental processGO:00510932010.014
immune response activating signal transductionGO:000275720.013
response to alkaloidGO:0043279260.013
purine ribonucleotide metabolic processGO:00091501450.013
l amino acid importGO:004309220.013
positive regulation of molecular functionGO:00440931360.013
purine nucleotide metabolic processGO:00061631460.013
neutral lipid catabolic processGO:004646130.013
chemotaxisGO:00069352490.013
Fly
detection of stimulusGO:00516061560.013
acylglycerol biosynthetic processGO:004646320.013
positive regulation of macromolecule biosynthetic processGO:00105572830.013
positive regulation of phosphorus metabolic processGO:00105621390.013
detection of stimulus involved in sensory perceptionGO:0050906920.013
epithelial cell migrationGO:00106311480.013
Fly
gene silencingGO:00164581380.013
male gamete generationGO:00482322010.013
Fly
axonogenesisGO:00074092900.013
Fly
immune response regulating signaling pathwayGO:000276420.013
cellular response to oxygen containing compoundGO:1901701790.013
axon guidanceGO:00074112330.013
Fly
positive regulation of rna metabolic processGO:00512542710.013
activation of innate immune responseGO:000221840.013
positive regulation of transcription dna templatedGO:00458932660.013
positive regulation of lipid storageGO:001088440.013
negative regulation of nucleic acid templated transcriptionGO:19035072400.013
single organism cellular localizationGO:19025801800.013
open tracheal system developmentGO:00074242040.013
Fly
agingGO:00075681430.013
Fly
developmental maturationGO:00217001720.013
ameboidal type cell migrationGO:00016671510.013
Fly
hindbrain developmentGO:003090220.013
actin cytoskeleton organizationGO:00300362060.013
ras protein signal transductionGO:0007265880.013
cellular hormone metabolic processGO:0034754230.013
triglyceride catabolic processGO:001943330.013
regulation of catabolic processGO:00098941700.013
carbohydrate metabolic processGO:0005975820.013
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.013
negative regulation of nucleobase containing compound metabolic processGO:00459342610.013
lauric acid metabolic processGO:004825210.013
hormone metabolic processGO:0042445330.013
segmentationGO:00352822070.013
peptidyl amino acid modificationGO:00181931050.013
regulation of hormone levelsGO:0010817400.013
positive regulation of intracellular signal transductionGO:19025331160.013
protein complex biogenesisGO:00702712010.013
sensory organ morphogenesisGO:00905962600.012
phosphate ion transportGO:000681740.012
maintenance of locationGO:0051235730.012
Fly
purine containing compound metabolic processGO:00725211550.012
cuticle developmentGO:0042335860.012
negative regulation of rna metabolic processGO:00512532510.012
regulation of anatomical structure morphogenesisGO:00226032420.012
nucleotide metabolic processGO:00091171610.012
positive regulation of phosphate metabolic processGO:00459371390.012
histolysisGO:00075591020.012
cellular lipid metabolic processGO:0044255830.012
mitotic cell cycle phase transitionGO:00447721380.012
regulation of programmed cell deathGO:00430671520.012
embryonic development via the syncytial blastodermGO:00017001480.012
limb developmentGO:006017310.012
secondary metabolic processGO:0019748750.012
chromatin modificationGO:00165681470.012
regulation of sequestering of triglycerideGO:001088930.012
cellular response to endogenous stimulusGO:0071495800.012
vitamin biosynthetic processGO:000911010.012
regulation of cellular response to stressGO:0080135890.012
cell cycle phase transitionGO:00447701400.012
fat soluble vitamin biosynthetic processGO:004236210.012
camera type eye morphogenesisGO:004859320.012
neutral lipid biosynthetic processGO:004646020.012
locomotory behaviorGO:00076261760.012
regulation of cellular catabolic processGO:00313291570.012
dendrite morphogenesisGO:00488131990.012
cellular response to lipopolysaccharideGO:007122230.012
ribose phosphate metabolic processGO:00196931450.012
cellular response to carbohydrate stimulusGO:007132240.012
negative regulation of multicellular organismal processGO:00512411420.012
regulation of phosphorylationGO:00423251470.012
regulation of synapse structure and activityGO:00508031280.012
actin filament organizationGO:00070151260.012
multi organism behaviorGO:00517051750.012
Fly
regulation of gene expression epigeneticGO:00400291280.012
chemosensory behaviorGO:00076351060.012
cation transportGO:00068121100.012
organonitrogen compound catabolic processGO:19015651280.012
Fly
positive regulation of catalytic activityGO:00430851180.012
cellular response to biotic stimulusGO:007121640.012
protein complex assemblyGO:00064612000.012
regulation of i kappab kinase nf kappab signalingGO:004312220.012
ribonucleotide metabolic processGO:00092591450.011
regulation of cell differentiationGO:00455953020.011
defense response to gram negative bacteriumGO:0050829940.011
posttranscriptional regulation of gene expressionGO:00106081450.011
pattern recognition receptor signaling pathwayGO:000222120.011
regulation of growthGO:00400082330.011
tissue migrationGO:00901301550.011
Fly
rna localizationGO:00064031150.011
chromatin organizationGO:00063252070.011
positive regulation of multicellular organismal processGO:00512401430.011
negative regulation of rna biosynthetic processGO:19026792400.011
detection of chemical stimulus involved in sensory perceptionGO:0050907750.011
signal transduction by phosphorylationGO:00230141070.011
regulation of lipid transportGO:003236830.011
organophosphate catabolic processGO:00464341120.011
protein hydroxylationGO:001812610.011
enzyme linked receptor protein signaling pathwayGO:00071671790.011
respiratory system developmentGO:00605412130.011
Fly
regulation of cellular localizationGO:00603411360.011
salivary gland histolysisGO:0035070880.011
regulation of nervous system developmentGO:00519602480.011
apoptotic processGO:00069151590.011
synapse assemblyGO:00074161430.011
retina development in camera type eyeGO:006004140.011
monocarboxylic acid transportGO:001571830.011
salivary gland cell autophagic cell deathGO:0035071830.011
positive regulation of catabolic processGO:00098961050.011
axis specificationGO:00097981670.011
wnt signaling pathwayGO:0016055980.011
regulation of cell substrate adhesionGO:001081020.011
dna metabolic processGO:00062592270.011
phosphatidylethanolamine metabolic processGO:004633710.011
regulation of organelle organizationGO:00330431960.011
response to mercury ionGO:004668930.011
cell divisionGO:00513012480.011
regulation of multi organism processGO:00439001310.011
intracellular protein transportGO:00068861040.011
cellular macromolecular complex assemblyGO:00346221530.011
sodium dependent phosphate transportGO:004434120.011
peptidyl proline hydroxylationGO:001951110.011
biological adhesionGO:00226101380.011
Fly
regulation of immune system processGO:00026821760.011
molting cycle chitin based cuticleGO:0007591560.011
phospholipid homeostasisGO:005509110.011
macromolecule catabolic processGO:00090571610.011
embryonic pattern specificationGO:00098801740.011
dendrite developmentGO:00163582040.011
innate immune response activating signal transductionGO:000275820.011
regulation of developmental growthGO:00486381740.011
multicellular organismal agingGO:00102591400.011
Fly
negative regulation of transcription dna templatedGO:00458922370.011
secretionGO:00469031090.011
regulation of epithelial cell proliferationGO:005067840.010
leg disc morphogenesisGO:0007478800.010
peptidyl proline modificationGO:001820830.010
behavioral response to painGO:004826630.010
positive regulation of cellular amine metabolic processGO:003324000.010
regulation of immune responseGO:00507761180.010
regulation of mitotic cell cycleGO:00073461900.010
mapk cascadeGO:00001651070.010
acetate ester metabolic processGO:190061920.010
Fly
acetylcholine metabolic processGO:000829120.010
Fly
negative regulation of protein metabolic processGO:0051248850.010
cytoplasmic transportGO:00164821300.010
protein heterooligomerizationGO:005129140.010
mesoderm developmentGO:0007498780.010
blastoderm segmentationGO:00073501590.010
regulation of hydrolase activityGO:0051336970.010
ion homeostasisGO:0050801550.010
positive regulation of cellular component organizationGO:00511301560.010
spermatogenesisGO:00072832000.010
Fly
carbohydrate derivative biosynthetic processGO:1901137850.010
negative regulation of cellular protein metabolic processGO:0032269850.010
response to painGO:004826530.010
regulation of epithelial cell differentiationGO:003085640.010
sensory perception of painGO:001923340.010
hematopoietic progenitor cell differentiationGO:000224410.010
synapse organizationGO:00508081960.010
drinking behaviorGO:004275620.010
positive regulation of cellular amino acid metabolic processGO:004576400.010
determination of adult lifespanGO:00083401370.010
Fly
response to heatGO:0009408630.010

alpha-Est4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.073
disease of metabolismDOID:001466700.023
nervous system diseaseDOID:86300.023
kidney diseaseDOID:55700.022
urinary system diseaseDOID:1800.022
renal tubular transport diseaseDOID:44700.022
musculoskeletal system diseaseDOID:1700.022
cardiovascular system diseaseDOID:128700.021
vascular diseaseDOID:17800.018
artery diseaseDOID:005082800.018
inherited metabolic disorderDOID:65500.017
acquired metabolic diseaseDOID:006015800.015
diabetes mellitusDOID:935100.013
glucose metabolism diseaseDOID:419400.013
carbohydrate metabolism diseaseDOID:005001300.013
type 2 diabetes mellitusDOID:935200.013
sensory system diseaseDOID:005015500.012
essential hypertensionDOID:1082500.012
hypertensionDOID:1076300.012
connective tissue diseaseDOID:6500.012
bone diseaseDOID:008000100.011
eye and adnexa diseaseDOID:149200.011
eye diseaseDOID:561400.011
central nervous system diseaseDOID:33100.011