Drosophila melanogaster

178 known processes

SCAR (Dmel_CG4636)

CG4636 gene product from transcript CG4636-RA

(Aliases: scar,BEST:SD02991,Dscar,l(2)k03107,D-SCAR,wave,dWAVE,WAVE,Wave,DWave,CG4636,Dmel\CG4636,Scar,DmSCAR,l(2)k13811)

SCAR biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
imaginal disc derived appendage morphogenesisGO:00351143950.234
cellular catabolic processGO:00442483720.224
establishment of localization in cellGO:00516494020.223
negative regulation of gene expressionGO:00106293870.215
organic acid metabolic processGO:00060821030.207
actin filament based processGO:00300292200.188
catabolic processGO:00090564090.162
imaginal disc derived appendage developmentGO:00487373990.155
appendage developmentGO:00487364010.148
ras protein signal transductionGO:0007265880.147
Human
growthGO:00400073590.145
negative regulation of rna metabolic processGO:00512532510.142
regulation of catabolic processGO:00098941700.140
negative regulation of nucleic acid templated transcriptionGO:19035072400.140
negative regulation of cellular biosynthetic processGO:00313272770.138
developmental growthGO:00485892800.127
cellular protein modification processGO:00064644380.126
actin cytoskeleton organizationGO:00300362060.123
negative regulation of nucleobase containing compound metabolic processGO:00459342610.122
epithelial cell differentiationGO:00308553220.113
post embryonic appendage morphogenesisGO:00351203850.113
positive regulation of biosynthetic processGO:00098913160.113
wing disc morphogenesisGO:00074723440.111
organic substance catabolic processGO:19015753080.106
protein localizationGO:00081042840.095
transcription from rna polymerase ii promoterGO:00063663680.094
oxoacid metabolic processGO:00434361030.093
positive regulation of nucleobase containing compound metabolic processGO:00459353320.092
regulation of cellular catabolic processGO:00313291570.089
regulation of intracellular signal transductionGO:19025312360.087
organic substance transportGO:00717022570.086
appendage morphogenesisGO:00351073970.085
negative regulation of signal transductionGO:00099682060.083
regulation of phosphorus metabolic processGO:00511742100.083
photoreceptor cell differentiationGO:00465301700.082
phosphorylationGO:00163102940.079
positive regulation of macromolecule biosynthetic processGO:00105572830.079
regulation of phosphate metabolic processGO:00192202100.078
negative regulation of nitrogen compound metabolic processGO:00511722650.077
stem cell divisionGO:0017145690.075
regulation of protein metabolic processGO:00512462560.075
regulation of cell morphogenesisGO:00226041630.074
negative regulation of transcription dna templatedGO:00458922370.074
regulation of multicellular organismal developmentGO:20000264140.073
negative regulation of macromolecule biosynthetic processGO:00105582700.072
eye morphogenesisGO:00485922600.072
protein modification processGO:00362114380.072
negative regulation of cellular metabolic processGO:00313243820.070
compound eye morphogenesisGO:00017452490.070
cellular macromolecule localizationGO:00707272200.069
endocytosisGO:00068973100.069
positive regulation of response to stimulusGO:00485843230.067
ribonucleoside metabolic processGO:00091191270.066
intracellular signal transductionGO:00355563000.065
Human
positive regulation of rab gtpase activityGO:003285170.064
nucleocytoplasmic transportGO:0006913720.064
cellular macromolecule catabolic processGO:00442651360.062
protein phosphorylationGO:00064681690.062
guanosine containing compound catabolic processGO:1901069740.062
axon developmentGO:00615642970.061
intracellular transportGO:00469072280.061
regulation of phosphorylationGO:00423251470.060
positive regulation of ras gtpase activityGO:0032320360.058
epithelial cell developmentGO:00020642740.058
positive regulation of catabolic processGO:00098961050.058
macromolecule catabolic processGO:00090571610.058
small molecule metabolic processGO:00442813050.057
sensory organ morphogenesisGO:00905962600.057
single organism intracellular transportGO:19025822070.056
positive regulation of cellular catabolic processGO:0031331950.056
regulation of growthGO:00400082330.055
cellular amine metabolic processGO:0044106120.055
columnar cuboidal epithelial cell differentiationGO:00020652560.054
embryonic morphogenesisGO:00485982060.054
regulation of cellular amino acid metabolic processGO:000652100.054
regulation of cellular ketone metabolic processGO:001056530.052
negative regulation of rna biosynthetic processGO:19026792400.052
regulation of transcription from rna polymerase ii promoterGO:00063573780.051
carboxylic acid metabolic processGO:0019752920.051
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.051
eye developmentGO:00016543230.051
localization of cellGO:00516742570.050
regulation of cellular amine metabolic processGO:003323830.050
protein transportGO:00150311550.050
small gtpase mediated signal transductionGO:0007264880.049
Human
aromatic compound catabolic processGO:00194391660.049
establishment of organelle localizationGO:00516561220.049
neuroblast divisionGO:0055057350.048
notch signaling pathwayGO:00072191200.048
anterior posterior pattern specificationGO:00099521360.047
gene silencingGO:00164581380.047
regulation of anatomical structure morphogenesisGO:00226032420.047
embryonic development via the syncytial blastodermGO:00017001480.046
regulation of notch signaling pathwayGO:00085931000.046
organonitrogen compound metabolic processGO:19015643180.046
regulation of ras gtpase activityGO:0032318380.046
protein modification by small protein conjugation or removalGO:00706471060.045
columnar cuboidal epithelial cell developmentGO:00020662490.045
response to abiotic stimulusGO:00096283410.045
g protein coupled receptor signaling pathwayGO:00071861360.045
positive regulation of gtpase activityGO:0043547430.045
eye photoreceptor cell differentiationGO:00017541450.044
cellular amino acid metabolic processGO:0006520610.044
stem cell differentiationGO:00488631170.044
digestive tract developmentGO:00485651490.044
regulation of rho protein signal transductionGO:0035023200.044
neuron projection guidanceGO:00974852410.043
positive regulation of nitrogen compound metabolic processGO:00511733540.043
negative regulation of signalingGO:00230572190.043
purine containing compound catabolic processGO:00725231120.043
nucleobase containing compound catabolic processGO:00346551650.042
regulation of cell shapeGO:00083601130.042
regulation of cellular component biogenesisGO:00440872010.042
regulation of programmed cell deathGO:00430671520.042
morphogenesis of an epitheliumGO:00020092760.041
response to radiationGO:00093141550.041
organic cyclic compound catabolic processGO:19013611680.041
compound eye developmentGO:00487493070.040
establishment of planar polarityGO:0001736870.040
positive regulation of macromolecule metabolic processGO:00106044050.039
imaginal disc derived wing morphogenesisGO:00074763370.039
cellular nitrogen compound catabolic processGO:00442701650.039
protein complex assemblyGO:00064612000.039
macromolecular complex assemblyGO:00650032560.038
carbohydrate derivative metabolic processGO:19011352170.038
modification dependent macromolecule catabolic processGO:0043632790.038
modification dependent protein catabolic processGO:0019941780.038
positive regulation of nucleotide metabolic processGO:0045981550.038
regulation of cell cycleGO:00517262910.037
cellular ketone metabolic processGO:0042180240.037
regulation of apoptotic processGO:00429811300.037
intracellular protein transportGO:00068861040.037
establishment or maintenance of cell polarityGO:00071631670.037
negative regulation of cell communicationGO:00106482230.037
nucleoside triphosphate metabolic processGO:00091411200.036
glycosyl compound metabolic processGO:19016571270.036
immune system processGO:00023763470.036
negative regulation of response to stimulusGO:00485852580.036
heterocycle catabolic processGO:00467001660.035
establishment of cell polarityGO:0030010400.035
glycosyl compound catabolic processGO:19016581120.035
dna metabolic processGO:00062592270.035
axis specificationGO:00097981670.035
gtp metabolic processGO:0046039720.035
positive regulation of rho gtpase activityGO:0032321190.035
ovarian follicle cell migrationGO:00072971210.034
negative regulation of biosynthetic processGO:00098902770.034
regulation of gene silencingGO:0060968630.034
hematopoietic progenitor cell differentiationGO:000224410.034
response to external biotic stimulusGO:00432072930.034
purine nucleoside catabolic processGO:00061521120.033
proteolysis involved in cellular protein catabolic processGO:0051603830.033
positive regulation of protein metabolic processGO:00512471280.033
regionalizationGO:00030024160.033
tube developmentGO:00352952440.033
regulation of molecular functionGO:00650092170.033
wnt signaling pathwayGO:0016055980.032
single organism behaviorGO:00447083910.032
positive regulation of phosphate metabolic processGO:00459371390.032
regulation of cellular protein metabolic processGO:00322682430.032
muscle structure developmentGO:00610612240.032
purine ribonucleotide catabolic processGO:00091541090.031
regulation of anatomical structure sizeGO:00900661630.031
purine containing compound metabolic processGO:00725211550.031
positive regulation of cell communicationGO:00106472500.031
positive regulation of nucleic acid templated transcriptionGO:19035082660.031
proteolysisGO:00065081920.031
organelle localizationGO:00516401480.031
positive regulation of cellular biosynthetic processGO:00313283160.030
positive regulation of nucleotide catabolic processGO:0030813460.030
ubiquitin dependent protein catabolic processGO:0006511780.030
negative regulation of developmental processGO:00510932010.030
cytoplasmic transportGO:00164821300.030
regulation of rho gtpase activityGO:0032319200.029
nucleoside triphosphate catabolic processGO:00091431080.029
nuclear divisionGO:00002803320.029
regulation of nucleoside metabolic processGO:0009118500.029
purine ribonucleoside triphosphate catabolic processGO:00092071080.029
carbohydrate derivative catabolic processGO:19011361180.029
regulation of organ morphogenesisGO:2000027780.029
amine metabolic processGO:0009308120.029
single organism cellular localizationGO:19025801800.029
positive regulation of nucleoside metabolic processGO:0045979470.029
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.029
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.029
regulation of wnt signaling pathwayGO:0030111680.028
cellular response to dna damage stimulusGO:00069742230.028
purine ribonucleoside catabolic processGO:00461301120.028
purine nucleotide catabolic processGO:00061951090.028
guanosine containing compound metabolic processGO:1901068740.028
organophosphate catabolic processGO:00464341120.028
purine nucleoside triphosphate metabolic processGO:00091441190.028
neural precursor cell proliferationGO:0061351750.028
renal tubule developmentGO:0061326640.028
imaginal disc derived wing vein morphogenesisGO:0008586440.027
establishment of tissue polarityGO:0007164870.027
mrna metabolic processGO:00160711240.027
programmed cell deathGO:00125012570.027
tissue morphogenesisGO:00487292970.027
compound eye photoreceptor cell differentiationGO:00017511400.027
cellular protein localizationGO:00346131600.027
regulation of epithelial cell differentiationGO:003085640.026
rna processingGO:00063961470.026
positive regulation of phosphorus metabolic processGO:00105621390.026
embryo development ending in birth or egg hatchingGO:00097921520.026
negative regulation of multicellular organismal processGO:00512411420.026
salivary gland morphogenesisGO:00074351450.025
purine ribonucleoside metabolic processGO:00461281270.025
regulation of actin cytoskeleton organizationGO:0032956420.025
germarium derived egg chamber formationGO:00072931010.025
positive regulation of cellular component organizationGO:00511301560.025
single organism catabolic processGO:00447122280.025
regulation of neurogenesisGO:00507671580.025
ribonucleoside triphosphate metabolic processGO:00091991190.025
regulation of catalytic activityGO:00507901850.025
nucleobase containing small molecule metabolic processGO:00550861740.025
regulation of mitotic cell cycleGO:00073461900.025
nuclear transportGO:0051169720.024
biological adhesionGO:00226101380.024
nucleotide metabolic processGO:00091171610.024
gtp catabolic processGO:0006184720.024
male gamete generationGO:00482322010.024
chromosome organizationGO:00512763600.024
immune response regulating signaling pathwayGO:000276420.024
hindbrain developmentGO:003090220.024
regulation of organelle organizationGO:00330431960.024
positive regulation of signal transductionGO:00099672230.024
positive regulation of wnt signaling pathwayGO:0030177250.024
axon guidanceGO:00074112330.024
immune responseGO:00069552460.023
organonitrogen compound catabolic processGO:19015651280.023
ribonucleoside triphosphate catabolic processGO:00092031080.023
response to lipopolysaccharideGO:003249640.023
camera type eye developmentGO:004301040.023
regulation of protein transportGO:0051223570.023
ribonucleotide catabolic processGO:00092611090.023
regulation of cell developmentGO:00602842150.022
posttranscriptional regulation of gene expressionGO:00106081450.022
regulation of nucleotide metabolic processGO:0006140620.022
body morphogenesisGO:001017120.022
enzyme linked receptor protein signaling pathwayGO:00071671790.022
protein catabolic processGO:00301631010.022
positive regulation of transcription dna templatedGO:00458932660.022
regulation of nucleotide catabolic processGO:0030811480.022
regulation of gtp catabolic processGO:0033124440.022
regulation of purine nucleotide metabolic processGO:1900542620.022
defense responseGO:00069523000.022
cell cell signaling involved in cell fate commitmentGO:00451682100.021
nitrogen compound transportGO:0071705850.021
negative regulation of cell differentiationGO:00455961430.021
axonogenesisGO:00074092900.021
positive regulation of gtp catabolic processGO:0033126430.021
protein complex biogenesisGO:00702712010.021
neuroblast proliferationGO:0007405740.021
salivary gland histolysisGO:0035070880.021
regulation of transportGO:00510491810.021
gland morphogenesisGO:00226121450.021
protein localization to organelleGO:0033365820.021
regulation of purine nucleotide catabolic processGO:0033121480.021
cell adhesionGO:00071551360.021
cell proliferationGO:00082832990.021
positive regulation of purine nucleotide metabolic processGO:1900544550.020
cell fate determinationGO:0001709910.020
positive regulation of cell motilityGO:200014730.020
actin filament organizationGO:00070151260.020
maintenance of locationGO:0051235730.020
purine nucleoside metabolic processGO:00422781270.020
rho protein signal transductionGO:0007266140.020
secretion by cellGO:00329401010.020
maintenance of location in cellGO:0051651280.020
salivary gland developmentGO:00074311620.020
ameboidal type cell migrationGO:00016671510.019
nuclear importGO:0051170510.019
organelle fissionGO:00482853400.019
blastoderm segmentationGO:00073501590.019
negative regulation of molecular functionGO:0044092510.019
photoreceptor cell fate commitmentGO:0046552410.019
positive regulation of cellular amino acid metabolic processGO:004576400.019
epithelium migrationGO:00901321480.019
homeostatic processGO:00425921990.019
response to biotic stimulusGO:00096072940.019
antimicrobial humoral responseGO:0019730990.019
mitotic nuclear divisionGO:00070672130.019
ribose phosphate metabolic processGO:00196931450.019
regulation of protein localizationGO:0032880760.019
chemotaxisGO:00069352490.018
purine nucleoside triphosphate catabolic processGO:00091461080.018
protein localization to nucleusGO:0034504550.018
regulation of cell projection organizationGO:0031344920.018
regulation of humoral immune responseGO:0002920510.018
regulation of gene expression epigeneticGO:00400291280.018
cellular protein catabolic processGO:0044257830.018
gene silencing by rnaGO:0031047570.018
deathGO:00162652840.018
cell motilityGO:00488702510.018
regulation of response to external stimulusGO:00321011150.018
anatomical structure homeostasisGO:0060249970.018
establishment or maintenance of bipolar cell polarityGO:0061245340.018
positive regulation of developmental processGO:00510941430.018
purine ribonucleoside triphosphate metabolic processGO:00092051190.018
positive regulation of signalingGO:00230562430.018
establishment of spindle localizationGO:0051293220.018
nucleotide catabolic processGO:00091661090.017
segmentationGO:00352822070.017
lateral inhibitionGO:00463312060.017
morphogenesis of follicular epitheliumGO:0016333360.017
positive regulation of rna metabolic processGO:00512542710.017
positive regulation of developmental growthGO:0048639620.017
morphogenesis of a polarized epitheliumGO:0001738930.017
jak stat cascadeGO:0007259490.017
erbb signaling pathwayGO:0038127580.017
cortical cytoskeleton organizationGO:0030865290.017
regulation of protein phosphorylationGO:0001932640.017
mapk cascadeGO:00001651070.017
response to other organismGO:00517072930.017
single organismal cell cell adhesionGO:0016337450.017
establishment of protein localizationGO:00451841630.017
regulation of hydrolase activityGO:0051336970.017
regulation of small gtpase mediated signal transductionGO:0051056930.016
multicellular organism growthGO:0035264460.016
protein targeting to nucleusGO:0044744510.016
spermatogenesisGO:00072832000.016
nucleoside catabolic processGO:00091641120.016
stem cell proliferationGO:0072089880.016
regulation of gtpase activityGO:0043087440.016
regulation of antimicrobial humoral responseGO:0002759500.016
exocrine system developmentGO:00352721620.016
response to heatGO:0009408630.016
positive regulation of hydrolase activityGO:0051345780.016
regulation of immune system processGO:00026821760.016
asymmetric neuroblast divisionGO:0055059330.016
regulation of response to stressGO:00801342000.016
chromatin silencingGO:0006342760.015
regulation of developmental growthGO:00486381740.015
regulation of localizationGO:00328792750.015
digestive system developmentGO:00551231490.015
humoral immune responseGO:00069591170.015
regulation of protein modification processGO:00313991120.015
central nervous system developmentGO:00074172010.015
positive regulation of purine nucleotide catabolic processGO:0033123460.015
cell divisionGO:00513012480.015
negative regulation of gene expression epigeneticGO:0045814770.015
cellular response to chemical stimulusGO:00708871990.015
posttranscriptional gene silencing by rnaGO:0035194450.015
chaeta developmentGO:0022416970.015
positive regulation of cell migrationGO:003033520.015
negative regulation of nervous system developmentGO:0051961920.015
alpha amino acid metabolic processGO:1901605200.015
ribonucleotide metabolic processGO:00092591450.015
positive regulation of cellular amine metabolic processGO:003324000.015
single organism carbohydrate metabolic processGO:0044723720.015
positive regulation of catalytic activityGO:00430851180.014
skin developmentGO:0043588650.014
immune response activating signal transductionGO:000275720.014
neurological system processGO:00508773580.014
cellular amide metabolic processGO:0043603800.014
nucleoside phosphate catabolic processGO:19012921100.014
cell deathGO:00082192790.014
regulation of cell differentiationGO:00455953020.014
cell projection assemblyGO:0030031940.014
regulation of kinase activityGO:0043549530.014
developmental growth involved in morphogenesisGO:0060560650.014
positive regulation of programmed cell deathGO:0043068620.014
purine ribonucleotide metabolic processGO:00091501450.014
camera type eye morphogenesisGO:004859320.014
locomotory behaviorGO:00076261760.014
positive regulation of organelle organizationGO:0010638650.014
nucleoside phosphate metabolic processGO:00067531620.014
regulation of cell deathGO:00109411730.014
ribonucleoside catabolic processGO:00424541120.014
photoreceptor cell developmentGO:0042461960.014
negative regulation of cell developmentGO:0010721620.014
positive regulation of gene expressionGO:00106282900.013
gland developmentGO:00487321910.013
regulation of nervous system developmentGO:00519602480.013
positive regulation of phosphorylationGO:0042327870.013
dendrite developmentGO:00163582040.013
chitin based cuticle developmentGO:0040003490.013
positive regulation of peptidyl tyrosine phosphorylationGO:005073140.013
response to organic substanceGO:00100332840.013
negative regulation of protein metabolic processGO:0051248850.013
brain developmentGO:00074201200.013
response to oxygen containing compoundGO:19017002000.013
stem cell maintenanceGO:0019827670.013
peptide metabolic processGO:0006518800.013
tripartite regional subdivisionGO:00073511030.013
hematopoietic or lymphoid organ developmentGO:0048534570.013
establishment of rna localizationGO:0051236470.013
endomembrane system organizationGO:00102561190.013
regulation of mapk cascadeGO:0043408920.013
organophosphate metabolic processGO:00196371950.013
gastrulationGO:0007369700.012
meiotic cell cycle processGO:19030461320.012
embryonic pattern specificationGO:00098801740.012
cellular component disassemblyGO:0022411460.012
positive regulation of cell deathGO:0010942690.012
oocyte localization involved in germarium derived egg chamber formationGO:0030720120.012
muscle cell differentiationGO:00426921030.012
multi organism behaviorGO:00517051750.012
spindle organizationGO:00070512530.012
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.012
negative regulation of notch signaling pathwayGO:0045746410.012
regulation of multicellular organism growthGO:0040014400.012
response to organonitrogen compoundGO:0010243750.012
regulation of transferase activityGO:0051338580.012
regulation of cell projection assemblyGO:0060491300.012
response to extracellular stimulusGO:00099911160.012
positive regulation of rac gtpase activityGO:003285580.012
protein targetingGO:0006605640.012
somatic stem cell divisionGO:0048103370.012
negative regulation of phosphate metabolic processGO:0045936450.012
ion transportGO:00068111450.012
developmental maturationGO:00217001720.012
single organism nuclear importGO:1902593510.012
carbohydrate metabolic processGO:0005975820.012
regulation of protein complex assemblyGO:0043254420.012
positive regulation of cellular component biogenesisGO:0044089800.012
apoptotic processGO:00069151590.012
positive regulation of transportGO:0051050920.012
peptide biosynthetic processGO:0043043420.011
immune system developmentGO:0002520570.011
regulation of protein polymerizationGO:0032271280.011
negative regulation of cell cycleGO:00457861160.011
mitotic spindle organizationGO:00070522200.011
transmembrane transportGO:00550851390.011
somatic muscle developmentGO:0007525660.011
rab protein signal transductionGO:003248260.011
protein importGO:0017038550.011
cellular homeostasisGO:0019725800.011
digestive tract morphogenesisGO:00485461270.011
cell migrationGO:00164772380.011
regulation of immune effector processGO:0002697520.011
chromatin organizationGO:00063252070.011
regulation of neuron differentiationGO:00456641030.011
peptidyl threonine phosphorylationGO:001810720.011
connective tissue developmentGO:006144830.011
dna packagingGO:0006323910.011
epithelial cell migrationGO:00106311480.011
eye photoreceptor cell developmentGO:0042462810.011
regulation of rab protein signal transductionGO:003248370.011
golgi organizationGO:0007030660.011
kidney developmentGO:000182230.011
neuronal stem cell divisionGO:0036445350.011
peptidyl tyrosine phosphorylationGO:0018108240.011
positive regulation of cellular protein metabolic processGO:00322701180.011
mesenchymal cell differentiationGO:004876210.011
microtubule based transportGO:0010970420.011
vesicle mediated transportGO:00161923810.011
multi multicellular organism processGO:00447061230.011
positive regulation of protein modification processGO:0031401580.010
taxisGO:00423303040.010
negative regulation of mitotic cell cycleGO:00459301090.010
ovarian follicle cell developmentGO:00307072480.010
positive regulation of rna biosynthetic processGO:19026802660.010
proteasomal protein catabolic processGO:0010498590.010
negative regulation of apoptotic processGO:0043066630.010
regulation of mrna metabolic processGO:1903311720.010
positive regulation of apoptotic processGO:0043065470.010
purine nucleotide metabolic processGO:00061631460.010
negative regulation of cell cycle processGO:00109481090.010
cellular response to organic substanceGO:00713101320.010

SCAR disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.067
nervous system diseaseDOID:86300.023
disease of cellular proliferationDOID:1456600.011
organ system cancerDOID:005068600.011
cancerDOID:16200.011