IMP: Integrative Multi-species Prediction

Drosophila melanogaster

17 known processes

CG6878 (Dmel_CG6878)

CG6878 gene product from transcript CG6878-RA

(Aliases: Dmel\CG6878)

Entrez: 39656
FLYBASE: FBgn0036488
UniProtKB: Q9VUM2

Process Predictions
Disease Predictions

CG6878 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
mitochondrion organization	GO:0007005	65	0.210
intracellular protein transmembrane import	GO:0044743	4	0.115
transmembrane transport	GO:0055085	139	0.091
organonitrogen compound metabolic process	GO:1901564	318	0.076
single organism intracellular transport	GO:1902582	207	0.074
intracellular protein transmembrane transport	GO:0065002	4	0.067
regulation of immune response	GO:0050776	118	0.065
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.063
response to oxidative stress	GO:0006979	86	0.060
protein targeting	GO:0006605	64	0.060
regulation of cell death	GO:0010941	173	0.050
organic substance transport	GO:0071702	257	0.050
cellular macromolecule localization	GO:0070727	220	0.050
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.049
establishment of protein localization	GO:0045184	163	0.047
cytoplasmic transport	GO:0016482	130	0.044
cellular amide metabolic process	GO:0043603	80	0.044
response to abiotic stimulus	GO:0009628	341	0.039
protein maturation	GO:0051604	71	0.037
immune response	GO:0006955	246	0.037
single organism membrane organization	GO:0044802	93	0.036
cellular lipid metabolic process	GO:0044255	83	0.035
defense response	GO:0006952	300	0.034
regulation of programmed cell death	GO:0043067	152	0.034
establishment of localization in cell	GO:0051649	402	0.033
protein transport	GO:0015031	155	0.033
regulation of phosphate metabolic process	GO:0019220	210	0.033
protein transmembrane transport	GO:0071806	4	0.032
developmental growth	GO:0048589	280	0.032
regulation of phosphorus metabolic process	GO:0051174	210	0.032
intracellular protein transport	GO:0006886	104	0.030
protein import	GO:0017038	55	0.030
cell proliferation	GO:0008283	299	0.030
protein complex assembly	GO:0006461	200	0.029
cation transmembrane transport	GO:0098655	88	0.029
intracellular transport	GO:0046907	228	0.029
single organism cellular localization	GO:1902580	180	0.029
response to organic substance	GO:0010033	284	0.029
regulation of apoptotic process	GO:0042981	130	0.029
negative regulation of rna metabolic process	GO:0051253	251	0.028
death	GO:0016265	284	0.028
positive regulation of programmed cell death	GO:0043068	62	0.027
cellular amine metabolic process	GO:0044106	12	0.027
negative regulation of cellular metabolic process	GO:0031324	382	0.027
vesicle mediated transport	GO:0016192	381	0.026
positive regulation of cell death	GO:0010942	69	0.024
endocytosis	GO:0006897	310	0.024
body morphogenesis	GO:0010171	2	0.024
oocyte differentiation	GO:0009994	145	0.024
peptide metabolic process	GO:0006518	80	0.024
cellular protein localization	GO:0034613	160	0.023
protein localization to organelle	GO:0033365	82	0.023
defense response to bacterium	GO:0042742	178	0.023
phagocytosis	GO:0006909	215	0.022
regulation of response to stress	GO:0080134	200	0.022
proteolysis	GO:0006508	192	0.022
protein processing	GO:0016485	68	0.021
phosphatidylethanolamine metabolic process	GO:0046337	1	0.021
regulation of localization	GO:0032879	275	0.021
organophosphate metabolic process	GO:0019637	195	0.021
immune system process	GO:0002376	347	0.021
positive regulation of cysteine type endopeptidase activity	GO:2001056	24	0.021
programmed cell death	GO:0012501	257	0.021
negative regulation of cell communication	GO:0010648	223	0.021
neurological system process	GO:0050877	358	0.021
cellular response to extracellular stimulus	GO:0031668	64	0.020
response to nutrient levels	GO:0031667	114	0.020
macromolecular complex assembly	GO:0065003	256	0.019
protein complex biogenesis	GO:0070271	201	0.019
regulation of innate immune response	GO:0045088	71	0.019
catabolic process	GO:0009056	409	0.019
intracellular signal transduction	GO:0035556	300	0.018
positive regulation of cysteine type endopeptidase activity involved in apoptotic process	GO:0043280	23	0.018
regulation of cellular protein metabolic process	GO:0032268	243	0.018
apoptotic process	GO:0006915	159	0.018
defense response to other organism	GO:0098542	225	0.018
carbohydrate derivative metabolic process	GO:1901135	217	0.018
response to biotic stimulus	GO:0009607	294	0.018
monovalent inorganic cation transport	GO:0015672	40	0.017
response to temperature stimulus	GO:0009266	106	0.017
response to external biotic stimulus	GO:0043207	293	0.017
regulation of molecular function	GO:0065009	217	0.017
cellular response to external stimulus	GO:0071496	66	0.017
immune response activating signal transduction	GO:0002757	2	0.017
negative regulation of cell death	GO:0060548	81	0.016
carboxylic acid metabolic process	GO:0019752	92	0.016
regulation of catalytic activity	GO:0050790	185	0.016
posttranscriptional regulation of gene expression	GO:0010608	145	0.016
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.016
positive regulation of response to stimulus	GO:0048584	323	0.016
positive regulation of endopeptidase activity	GO:0010950	26	0.016
cation transport	GO:0006812	110	0.016
amine metabolic process	GO:0009308	12	0.016
single organism biosynthetic process	GO:0044711	206	0.016
membrane organization	GO:0061024	112	0.016
cellular amino acid metabolic process	GO:0006520	61	0.015
biological adhesion	GO:0022610	138	0.015
homeostatic process	GO:0042592	199	0.015
positive regulation of peptidase activity	GO:0010952	29	0.015
organic substance catabolic process	GO:1901575	308	0.015
ribonucleoside metabolic process	GO:0009119	127	0.015
phosphorylation	GO:0016310	294	0.015
protein targeting to mitochondrion	GO:0006626	1	0.015
glycerolipid metabolic process	GO:0046486	34	0.014
negative regulation of biosynthetic process	GO:0009890	277	0.014
immune response regulating signaling pathway	GO:0002764	2	0.014
organic hydroxy compound metabolic process	GO:1901615	83	0.014
detection of chemical stimulus	GO:0009593	93	0.014
developmental programmed cell death	GO:0010623	138	0.014
negative regulation of rna biosynthetic process	GO:1902679	240	0.014
establishment of protein localization to organelle	GO:0072594	62	0.014
positive regulation of molecular function	GO:0044093	136	0.014
protein localization to mitochondrion	GO:0070585	1	0.014
cell adhesion	GO:0007155	136	0.013
developmental maturation	GO:0021700	172	0.013
ion transport	GO:0006811	145	0.013
growth	GO:0040007	359	0.013
cellular response to dna damage stimulus	GO:0006974	223	0.013
negative regulation of programmed cell death	GO:0043069	72	0.013
dna metabolic process	GO:0006259	227	0.013
negative regulation of cellular biosynthetic process	GO:0031327	277	0.013
small molecule metabolic process	GO:0044281	305	0.013
activation of cysteine type endopeptidase activity	GO:0097202	17	0.013
regulation of protein metabolic process	GO:0051246	256	0.012
regulation of cellular amine metabolic process	GO:0033238	3	0.012
transcription from rna polymerase ii promoter	GO:0006366	368	0.012
mitochondrial transport	GO:0006839	8	0.012
negative regulation of signaling	GO:0023057	219	0.012
neuromuscular junction development	GO:0007528	149	0.012
response to bacterium	GO:0009617	198	0.012
negative regulation of phosphate metabolic process	GO:0045936	45	0.012
regulation of hydrolase activity	GO:0051336	97	0.012
negative regulation of response to stimulus	GO:0048585	258	0.012
salivary gland histolysis	GO:0035070	88	0.012
cellular response to chemical stimulus	GO:0070887	199	0.012
response to extracellular stimulus	GO:0009991	116	0.012
aging	GO:0007568	143	0.012
cell aging	GO:0007569	2	0.012
cellular catabolic process	GO:0044248	372	0.012
cellular nitrogen compound catabolic process	GO:0044270	165	0.012
purine nucleotide metabolic process	GO:0006163	146	0.012
negative regulation of transcription dna templated	GO:0045892	237	0.012
innate immune response	GO:0045087	144	0.012
ethanolamine containing compound metabolic process	GO:0042439	4	0.011
single organism behavior	GO:0044708	391	0.011
protein modification process	GO:0036211	438	0.011
cellular macromolecular complex assembly	GO:0034622	153	0.011
regulation of cysteine type endopeptidase activity involved in apoptotic process	GO:0043281	25	0.011
oxoacid metabolic process	GO:0043436	103	0.011
positive regulation of apoptotic process	GO:0043065	47	0.011
negative regulation of apoptotic process	GO:0043066	63	0.011
response to oxygen containing compound	GO:1901700	200	0.011
response to heat	GO:0009408	63	0.010
rna processing	GO:0006396	147	0.010
lipid biosynthetic process	GO:0008610	46	0.010
single organism catabolic process	GO:0044712	228	0.010
defense response to gram negative bacterium	GO:0050829	94	0.010
negative regulation of signal transduction	GO:0009968	206	0.010
lipid metabolic process	GO:0006629	121	0.010
regulation of transport	GO:0051049	181	0.010
detection of stimulus	GO:0051606	156	0.010
positive regulation of apoptotic signaling pathway	GO:2001235	4	0.010

CG6878 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.046
nervous system disease	DOID:863	0.023
central nervous system disease	DOID:331	0.014
disease of metabolism	DOID:0014667	0.014
inherited metabolic disorder	DOID:655	0.014
disease of cellular proliferation	DOID:14566	0.012
cancer	DOID:162	0.012
organ system cancer	DOID:0050686	0.012

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