IMP: Integrative Multi-species Prediction

Drosophila melanogaster

97 known processes

SmD3 (Dmel_CG8427)

Small ribonucleoprotein particle protein SmD3

(Aliases: l(2)154/1,guf2,guf,Sm D3,dD3,l(2)131/7,l(2)90/37,CG8427,Dmel\CG8427,snRNP Sm D3,SYM10,smD3)

Entrez: 36306
FLYBASE: FBgn0023167
UniProtKB: O44437

Process Predictions
Disease Predictions

SmD3 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
muscle structure development	GO:0061061	224	0.887
muscle organ development	GO:0007517	127	0.882
multi organism reproductive behavior	GO:0044705	121	0.873
nuclear division	GO:0000280	332	0.683
axon development	GO:0061564	297	0.384
central nervous system development	GO:0007417	201	0.360
histone acetylation	GO:0016573	38	0.333
organelle fission	GO:0048285	340	0.320
posttranscriptional gene silencing by rna	GO:0035194	45	0.317
protein modification by small protein conjugation	GO:0032446	79	0.285
gland development	GO:0048732	191	0.284
meiotic cell cycle	GO:0051321	171	0.266
axonogenesis	GO:0007409	290	0.263
multi organism behavior	GO:0051705	175	0.262
locomotory behavior	GO:0007626	176	0.257
larval development	GO:0002164	104	0.248	Worm
cell death	GO:0008219	279	0.243	Worm
embryo development ending in birth or egg hatching	GO:0009792	152	0.243	Worm
multicellular organismal reproductive behavior	GO:0033057	110	0.231
pole cell formation	GO:0007279	19	0.230
reproductive system development	GO:0061458	74	0.226
nucleotide metabolic process	GO:0009117	161	0.225
rna interference	GO:0016246	27	0.213
multi multicellular organism process	GO:0044706	123	0.203
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.203
positive regulation of cellular biosynthetic process	GO:0031328	316	0.196
dna conformation change	GO:0071103	105	0.193
organophosphate metabolic process	GO:0019637	195	0.189
positive regulation of rna metabolic process	GO:0051254	271	0.186
macromolecular complex assembly	GO:0065003	256	0.174	Human
chromosome organization	GO:0051276	360	0.169
cellular macromolecular complex assembly	GO:0034622	153	0.154	Human
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.149
multicellular organismal aging	GO:0010259	140	0.148
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.136
positive regulation of macromolecule metabolic process	GO:0010604	405	0.133
meiotic nuclear division	GO:0007126	151	0.131
protein complex biogenesis	GO:0070271	201	0.128
purine nucleotide metabolic process	GO:0006163	146	0.116
cell motility	GO:0048870	251	0.115
nucleobase containing small molecule metabolic process	GO:0055086	174	0.112
chromatin organization	GO:0006325	207	0.112
sex differentiation	GO:0007548	81	0.111
determination of adult lifespan	GO:0008340	137	0.111
positive regulation of rna biosynthetic process	GO:1902680	266	0.110
response to organic substance	GO:0010033	284	0.110
dna templated transcription initiation	GO:0006352	25	0.110
purine ribonucleoside metabolic process	GO:0046128	127	0.108
muscle cell differentiation	GO:0042692	103	0.106
purine containing compound catabolic process	GO:0072523	112	0.104
reproductive behavior	GO:0019098	122	0.097
regulation of cell proliferation	GO:0042127	163	0.096
body morphogenesis	GO:0010171	2	0.096
neuron projection guidance	GO:0097485	241	0.095
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.094
transcription from rna polymerase ii promoter	GO:0006366	368	0.089
striated muscle cell differentiation	GO:0051146	90	0.089
dna metabolic process	GO:0006259	227	0.087
regulation of cell death	GO:0010941	173	0.087
regulation of dna metabolic process	GO:0051052	34	0.085
actomyosin structure organization	GO:0031032	56	0.082
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.077
cellular component assembly involved in morphogenesis	GO:0010927	151	0.076
rna processing	GO:0006396	147	0.075	Human Yeast
posttranscriptional gene silencing	GO:0016441	46	0.075
catabolic process	GO:0009056	409	0.074
response to biotic stimulus	GO:0009607	294	0.072
chromatin modification	GO:0016568	147	0.072
positive regulation of biosynthetic process	GO:0009891	316	0.070
histone modification	GO:0016570	106	0.068
localization of cell	GO:0051674	257	0.068
regulation of cell division	GO:0051302	72	0.067
regulation of meiosis	GO:0040020	3	0.065
regulation of apoptotic process	GO:0042981	130	0.065
cellular protein modification process	GO:0006464	438	0.064
positive regulation of transcription dna templated	GO:0045893	266	0.064
aging	GO:0007568	143	0.063
carbohydrate derivative metabolic process	GO:1901135	217	0.060
chemotaxis	GO:0006935	249	0.059
small molecule metabolic process	GO:0044281	305	0.058
cell proliferation	GO:0008283	299	0.058
mrna metabolic process	GO:0016071	124	0.058	Human Yeast
positive regulation of catabolic process	GO:0009896	105	0.056
death	GO:0016265	284	0.056	Worm
cell cycle comprising mitosis without cytokinesis	GO:0033301	25	0.055
heart development	GO:0007507	82	0.055
tube development	GO:0035295	244	0.055
cellularization	GO:0007349	90	0.053
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.053
regulation of developmental growth	GO:0048638	174	0.052
negative regulation of developmental process	GO:0051093	201	0.052	Worm
axon guidance	GO:0007411	233	0.050
taxis	GO:0042330	304	0.050
regulation of catabolic process	GO:0009894	170	0.048
chromosome segregation	GO:0007059	157	0.048
cellular response to chemical stimulus	GO:0070887	199	0.047
regulation of multi organism process	GO:0043900	131	0.046
mitotic spindle organization	GO:0007052	220	0.046
cell migration	GO:0016477	238	0.046
tube morphogenesis	GO:0035239	191	0.043
protein modification by small protein conjugation or removal	GO:0070647	106	0.043
purine ribonucleoside catabolic process	GO:0046130	112	0.041
spindle organization	GO:0007051	253	0.041
negative regulation of multicellular organismal process	GO:0051241	142	0.040	Worm
humoral immune response	GO:0006959	117	0.040
maintenance of location	GO:0051235	73	0.040
regulation of multicellular organismal development	GO:2000026	414	0.039	Worm
covalent chromatin modification	GO:0016569	106	0.039
nucleoside triphosphate metabolic process	GO:0009141	120	0.038
pole cell development	GO:0007277	26	0.038
organonitrogen compound metabolic process	GO:1901564	318	0.038
growth	GO:0040007	359	0.038
mitotic nuclear division	GO:0007067	213	0.037
purine nucleotide catabolic process	GO:0006195	109	0.037
regulation of cellular catabolic process	GO:0031329	157	0.036
ubiquitin dependent protein catabolic process	GO:0006511	78	0.036
development of primary sexual characteristics	GO:0045137	50	0.036
ribonucleoside catabolic process	GO:0042454	112	0.035
positive regulation of cellular component biogenesis	GO:0044089	80	0.035
negative regulation of response to stimulus	GO:0048585	258	0.035
ribonucleotide catabolic process	GO:0009261	109	0.034
negative regulation of signaling	GO:0023057	219	0.032
nucleoside phosphate metabolic process	GO:0006753	162	0.031
protein acetylation	GO:0006473	39	0.031
digestive tract development	GO:0048565	149	0.031
salivary gland morphogenesis	GO:0007435	145	0.031
nucleotide catabolic process	GO:0009166	109	0.030
smoothened signaling pathway	GO:0007224	49	0.030
response to oxygen containing compound	GO:1901700	200	0.030
nucleoside metabolic process	GO:0009116	127	0.030
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.030
reproductive structure development	GO:0048608	74	0.030
cell division	GO:0051301	248	0.029
regulation of i kappab kinase nf kappab signaling	GO:0043122	2	0.029
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.029
protein ubiquitination	GO:0016567	70	0.029
dna packaging	GO:0006323	91	0.029
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.029
organelle assembly	GO:0070925	198	0.028
regulation of programmed cell death	GO:0043067	152	0.028
gonad development	GO:0008406	50	0.028
purine nucleoside catabolic process	GO:0006152	112	0.028
mitotic chromosome condensation	GO:0007076	22	0.027
response to external biotic stimulus	GO:0043207	293	0.027
regulation of cell cycle process	GO:0010564	181	0.027
regulation of mitotic cell cycle	GO:0007346	190	0.027
cellular protein catabolic process	GO:0044257	83	0.027
glycosyl compound metabolic process	GO:1901657	127	0.027
mrna processing	GO:0006397	104	0.026	Human Yeast
positive regulation of signal transduction	GO:0009967	223	0.026
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.025
mrna splicing via spliceosome	GO:0000398	73	0.025	Human Yeast
female meiotic division	GO:0007143	70	0.025
programmed cell death	GO:0012501	257	0.025	Worm
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.024
dendrite morphogenesis	GO:0048813	199	0.024
nucleoside catabolic process	GO:0009164	112	0.024
gene silencing by rna	GO:0031047	57	0.023
regulation of nuclear division	GO:0051783	58	0.023
purine ribonucleotide metabolic process	GO:0009150	145	0.023
regulation of catalytic activity	GO:0050790	185	0.022
cellular catabolic process	GO:0044248	372	0.022
ribonucleoprotein complex biogenesis	GO:0022613	31	0.022	Human
establishment of nucleus localization	GO:0040023	26	0.022
mitotic cell cycle phase transition	GO:0044772	138	0.022
organophosphate catabolic process	GO:0046434	112	0.022
negative regulation of rna biosynthetic process	GO:1902679	240	0.021
purine nucleoside metabolic process	GO:0042278	127	0.021
regulation of cellular component biogenesis	GO:0044087	201	0.021
apoptotic process	GO:0006915	159	0.021	Worm
regulation of response to external stimulus	GO:0032101	115	0.021
purine containing compound metabolic process	GO:0072521	155	0.021
peptidyl lysine acetylation	GO:0018394	39	0.021
mesoderm development	GO:0007498	78	0.021
positive regulation of response to stimulus	GO:0048584	323	0.021
cellular response to dna damage stimulus	GO:0006974	223	0.021
organic substance catabolic process	GO:1901575	308	0.021
protein complex assembly	GO:0006461	200	0.020
glycosyl compound catabolic process	GO:1901658	112	0.020
regulation of meiotic cell cycle	GO:0051445	9	0.020
sister chromatid segregation	GO:0000819	92	0.020
ribonucleotide metabolic process	GO:0009259	145	0.020
oviposition	GO:0018991	19	0.020
regulation of intracellular signal transduction	GO:1902531	236	0.019
single organism biosynthetic process	GO:0044711	206	0.019
rhythmic process	GO:0048511	106	0.019
negative regulation of cellular metabolic process	GO:0031324	382	0.019
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.019
negative regulation of gene expression	GO:0010629	387	0.018
chromatin remodeling	GO:0006338	72	0.018
positive regulation of cell communication	GO:0010647	250	0.018
rna splicing	GO:0008380	83	0.018	Human Yeast
genitalia development	GO:0048806	26	0.018
ribonucleoprotein complex assembly	GO:0022618	23	0.018	Human
negative regulation of cellular catabolic process	GO:0031330	34	0.018
neurological system process	GO:0050877	358	0.018
positive regulation of signaling	GO:0023056	243	0.018
purine ribonucleotide catabolic process	GO:0009154	109	0.018
regulation of phosphorus metabolic process	GO:0051174	210	0.017
homeostatic process	GO:0042592	199	0.017
positive regulation of nucleocytoplasmic transport	GO:0046824	24	0.017
nucleoside phosphate catabolic process	GO:1901292	110	0.017
positive regulation of gene expression	GO:0010628	290	0.017
ribose phosphate metabolic process	GO:0019693	145	0.017
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.017
neural retina development	GO:0003407	4	0.017
anatomical structure homeostasis	GO:0060249	97	0.017
striated muscle cell development	GO:0055002	50	0.017
chromosome condensation	GO:0030261	41	0.016
intracellular receptor signaling pathway	GO:0030522	19	0.016
male gamete generation	GO:0048232	201	0.016
organic cyclic compound catabolic process	GO:1901361	168	0.016
exocrine system development	GO:0035272	162	0.016
salivary gland development	GO:0007431	162	0.016
positive regulation of gtp catabolic process	GO:0033126	43	0.015
protein acylation	GO:0043543	42	0.015
peptidyl amino acid modification	GO:0018193	105	0.015
ribonucleoside metabolic process	GO:0009119	127	0.015
internal peptidyl lysine acetylation	GO:0018393	38	0.015
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.015
gene silencing	GO:0016458	138	0.014
gtp metabolic process	GO:0046039	72	0.014
single organism catabolic process	GO:0044712	228	0.014
telencephalon development	GO:0021537	2	0.014
negative regulation of cell communication	GO:0010648	223	0.014
negative regulation of intrinsic apoptotic signaling pathway	GO:2001243	1	0.014
chromatin assembly or disassembly	GO:0006333	52	0.014
instar larval development	GO:0002168	55	0.014
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.014
striated muscle myosin thick filament assembly	GO:0071688	3	0.014
phosphorylation	GO:0016310	294	0.014
glandular epithelial cell differentiation	GO:0002067	1	0.014
regulation of molecular function	GO:0065009	217	0.013
myofibril assembly	GO:0030239	36	0.013
regulation of cell cycle	GO:0051726	291	0.013
positive regulation of programmed cell death	GO:0043068	62	0.013
positive regulation of catalytic activity	GO:0043085	118	0.013
cytokinesis	GO:0000910	90	0.013
modification dependent macromolecule catabolic process	GO:0043632	79	0.012
cellular response to oxygen containing compound	GO:1901701	79	0.012
positive regulation of molecular function	GO:0044093	136	0.012
response to endogenous stimulus	GO:0009719	119	0.012
response to nitrogen compound	GO:1901698	90	0.012
regulation of protein modification process	GO:0031399	112	0.012
mitotic cell cycle embryonic	GO:0045448	38	0.012
regulation of protein metabolic process	GO:0051246	256	0.012
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.012
cellular response to endogenous stimulus	GO:0071495	80	0.012
regulation of cellular response to stress	GO:0080135	89	0.012
positive regulation of phosphorus metabolic process	GO:0010562	139	0.011
regulation of hemocyte proliferation	GO:0035206	37	0.011
positive regulation of hydrolase activity	GO:0051345	78	0.011
guanosine containing compound metabolic process	GO:1901068	74	0.011
carbohydrate derivative catabolic process	GO:1901136	118	0.011
protein localization	GO:0008104	284	0.011
negative regulation of epithelial cell proliferation	GO:0050680	4	0.011
protein catabolic process	GO:0030163	101	0.011
protein polymerization	GO:0051258	42	0.011
muscle cell development	GO:0055001	50	0.011
synapse organization	GO:0050808	196	0.010
centriole assembly	GO:0098534	24	0.010
gland morphogenesis	GO:0022612	145	0.010
regulation of growth	GO:0040008	233	0.010
nuclear envelope organization	GO:0006998	7	0.010
cellular nitrogen compound catabolic process	GO:0044270	165	0.010

SmD3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org

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