Drosophila melanogaster

0 known processes

Jhedup (Dmel_CG8424)

Juvenile hormone esterase duplication

(Aliases: Dmel\CG8424,JHEdup,CG8424)

Jhedup biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
sensory perception of chemical stimulusGO:00076061160.125
sensory perception of smellGO:0007608800.054
imaginal disc derived appendage developmentGO:00487373990.044
appendage morphogenesisGO:00351073970.043
neurological system processGO:00508773580.042
response to organic substanceGO:00100332840.040
Fly
sensory perceptionGO:00076001960.040
wing disc morphogenesisGO:00074723440.038
imaginal disc derived appendage morphogenesisGO:00351143950.038
appendage developmentGO:00487364010.037
single organism behaviorGO:00447083910.036
Fly
imaginal disc derived wing morphogenesisGO:00074763370.036
anion homeostasisGO:005508130.035
post embryonic appendage morphogenesisGO:00351203850.035
organonitrogen compound metabolic processGO:19015643180.035
response to abiotic stimulusGO:00096283410.034
small molecule metabolic processGO:00442813050.032
response to other organismGO:00517072930.032
response to biotic stimulusGO:00096072940.032
protein modification processGO:00362114380.032
lateral inhibitionGO:00463312060.032
multi organism behaviorGO:00517051750.031
Fly
cell cell signaling involved in cell fate commitmentGO:00451682100.031
detection of stimulusGO:00516061560.031
defense response to other organismGO:00985422250.030
regulation of localizationGO:00328792750.030
carboxylic acid metabolic processGO:0019752920.029
endocytosisGO:00068973100.029
xenobiotic catabolic processGO:004217810.029
cellular protein modification processGO:00064644380.029
catabolic processGO:00090564090.029
Fly
cellular catabolic processGO:00442483720.029
Fly
organic acid metabolic processGO:00060821030.028
sterol homeostasisGO:005509240.028
negative regulation of gene expressionGO:00106293870.028
detection of chemical stimulusGO:0009593930.028
vesicle mediated transportGO:00161923810.027
immune system processGO:00023763470.027
single organism biosynthetic processGO:00447112060.027
Fly
regulation of multicellular organismal developmentGO:20000264140.027
organic substance catabolic processGO:19015753080.027
Fly
phagocytosisGO:00069092150.026
eye developmentGO:00016543230.026
positive regulation of response to stimulusGO:00485843230.026
defense response to bacteriumGO:00427421780.026
hormone catabolic processGO:004244730.026
Fly
salt aversionGO:003519930.026
oxoacid metabolic processGO:00434361030.026
response to lipopolysaccharideGO:003249640.026
negative regulation of cellular metabolic processGO:00313243820.025
cholesterol homeostasisGO:004263230.025
response to bacteriumGO:00096171980.025
immune responseGO:00069552460.025
response to extracellular stimulusGO:00099911160.025
camera type eye developmentGO:004301040.025
matingGO:00076181200.025
Fly
regulation of multi organism processGO:00439001310.025
positive regulation of macromolecule metabolic processGO:00106044050.024
developmental growthGO:00485892800.024
compound eye developmentGO:00487493070.024
sensory perception of salty tasteGO:005091430.024
detection of stimulus involved in sensory perceptionGO:0050906920.024
response to external biotic stimulusGO:00432072930.024
organic substance transportGO:00717022570.024
negative regulation of response to stimulusGO:00485852580.024
body morphogenesisGO:001017120.023
homeostatic processGO:00425921990.023
positive regulation of cell communicationGO:00106472500.023
negative regulation of nitrogen compound metabolic processGO:00511722650.023
cellular amino acid metabolic processGO:0006520610.023
steroid catabolic processGO:000670610.023
kidney developmentGO:000182230.023
nuclear divisionGO:00002803320.023
positive regulation of biosynthetic processGO:00098913160.023
positive regulation of nucleobase containing compound metabolic processGO:00459353320.023
multi organism reproductive behaviorGO:00447051210.023
Fly
positive regulation of cellular biosynthetic processGO:00313283160.023
intracellular signal transductionGO:00355563000.023
growthGO:00400073590.022
regionalizationGO:00030024160.022
gland developmentGO:00487321910.022
regulation of transportGO:00510491810.022
regulation of immune system processGO:00026821760.022
positive regulation of nitrogen compound metabolic processGO:00511733540.022
taxisGO:00423303040.022
macromolecular complex assemblyGO:00650032560.022
cell proliferationGO:00082832990.022
forebrain developmentGO:003090020.022
transcription from rna polymerase ii promoterGO:00063663680.022
regulation of cell cycleGO:00517262910.022
regulation of immune responseGO:00507761180.022
connective tissue developmentGO:006144830.022
organelle fissionGO:00482853400.022
defense responseGO:00069523000.022
cell deathGO:00082192790.021
positive regulation of signal transductionGO:00099672230.021
rhythmic processGO:00485111060.021
response to organophosphorusGO:004668320.021
compound eye morphogenesisGO:00017452490.021
ethanolamine containing compound metabolic processGO:004243940.021
adult behaviorGO:00305341370.021
Fly
positive regulation of rna biosynthetic processGO:19026802660.020
positive regulation of macromolecule biosynthetic processGO:00105572830.020
acylglycerol catabolic processGO:004646430.020
exocrine system developmentGO:00352721620.020
detection of chemical stimulus involved in sensory perceptionGO:0050907750.020
cellular ketone metabolic processGO:0042180240.020
positive regulation of signalingGO:00230562430.020
salivary gland developmentGO:00074311620.020
negative regulation of signal transductionGO:00099682060.020
negative regulation of rna metabolic processGO:00512532510.020
triglyceride catabolic processGO:001943330.020
positive regulation of lipid storageGO:001088440.020
amine metabolic processGO:0009308120.020
protein hydroxylationGO:001812610.019
regulation of cellular amine metabolic processGO:003323830.019
cellular amine metabolic processGO:0044106120.019
carbohydrate derivative metabolic processGO:19011352170.019
regulation of protein metabolic processGO:00512462560.019
neutral lipid biosynthetic processGO:004646020.019
sensory organ morphogenesisGO:00905962600.019
eye morphogenesisGO:00485922600.019
negative regulation of biosynthetic processGO:00098902770.019
cell divisionGO:00513012480.019
cellular response to chemical stimulusGO:00708871990.019
detection of chemical stimulus involved in sensory perception of smellGO:0050911500.019
positive regulation of nucleic acid templated transcriptionGO:19035082660.019
tissue morphogenesisGO:00487292970.019
negative regulation of nucleic acid templated transcriptionGO:19035072400.019
triglyceride biosynthetic processGO:001943220.019
lipid metabolic processGO:00066291210.019
Fly
response to nutrient levelsGO:00316671140.019
positive regulation of transcription dna templatedGO:00458932660.019
regulation of response to external stimulusGO:00321011150.019
regulation of cellular ketone metabolic processGO:001056530.019
male courtship behaviorGO:0008049630.018
single organism catabolic processGO:00447122280.018
Fly
ion transportGO:00068111450.018
antimicrobial humoral responseGO:0019730990.018
negative regulation of cellular biosynthetic processGO:00313272770.018
developmental maturationGO:00217001720.018
response to oxygen containing compoundGO:19017002000.018
Fly
negative regulation of macromolecule biosynthetic processGO:00105582700.018
cellular response to ethanolGO:007136140.018
defense response to gram negative bacteriumGO:0050829940.018
regulation of transcription from rna polymerase ii promoterGO:00063573780.018
positive regulation of gene expressionGO:00106282900.018
regulation of antimicrobial humoral responseGO:0002759500.018
establishment of localization in cellGO:00516494020.018
programmed cell deathGO:00125012570.018
organophosphate metabolic processGO:00196371950.018
segmentationGO:00352822070.018
negative regulation of rna biosynthetic processGO:19026792400.018
reproductive behaviorGO:00190981220.018
Fly
chromosome organizationGO:00512763600.018
humoral immune responseGO:00069591170.018
response to radiationGO:00093141550.018
salivary gland morphogenesisGO:00074351450.018
regulation of response to stressGO:00801342000.018
fat soluble vitamin metabolic processGO:000677510.018
negative regulation of signalingGO:00230572190.018
positive regulation of multicellular organismal processGO:00512401430.017
gland morphogenesisGO:00226121450.017
phosphatidylethanolamine metabolic processGO:004633710.017
regulation of sequestering of triglycerideGO:001088930.017
morphogenesis of an epitheliumGO:00020092760.017
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.017
fat soluble vitamin biosynthetic processGO:004236210.017
epithelial cell differentiationGO:00308553220.017
phosphorylationGO:00163102940.017
regulation of molecular functionGO:00650092170.017
positive regulation of rna metabolic processGO:00512542710.017
negative regulation of transcription dna templatedGO:00458922370.017
regulation of cell differentiationGO:00455953020.017
response to pheromoneGO:0019236190.017
negative regulation of cell communicationGO:00106482230.017
protein localizationGO:00081042840.017
embryonic pattern specificationGO:00098801740.017
polyol biosynthetic processGO:004617330.017
regulation of catalytic activityGO:00507901850.016
androgen metabolic processGO:000820910.016
spindle organizationGO:00070512530.016
benzene containing compound metabolic processGO:004253730.016
proteolysisGO:00065081920.016
regulation of cellular protein metabolic processGO:00322682430.016
organic cyclic compound catabolic processGO:19013611680.016
pigmentationGO:0043473750.016
regulation of cellular amino acid metabolic processGO:000652100.016
regulation of i kappab kinase nf kappab signalingGO:004312220.016
limb developmentGO:006017310.016
negative regulation of nucleobase containing compound metabolic processGO:00459342610.016
retina development in camera type eyeGO:006004140.016
telencephalon developmentGO:002153720.016
regulation of mitotic cell cycleGO:00073461900.016
multicellular organismal reproductive behaviorGO:00330571100.016
Fly
vitamin biosynthetic processGO:000911010.016
phospholipid homeostasisGO:005509110.016
regulation of synapse structure and activityGO:00508031280.016
chemosensory behaviorGO:00076351060.016
regulation of intracellular signal transductionGO:19025312360.016
peptidyl proline hydroxylationGO:001951110.016
acylglycerol biosynthetic processGO:004646320.016
cellular nitrogen compound catabolic processGO:00442701650.016
glycerolipid catabolic processGO:004650330.016
medium chain fatty acid metabolic processGO:005179110.015
developmental programmed cell deathGO:00106231380.015
open tracheal system developmentGO:00074242040.015
regulation of cellular component biogenesisGO:00440872010.015
g protein coupled receptor signaling pathwayGO:00071861360.015
multi multicellular organism processGO:00447061230.015
Fly
negative regulation of developmental processGO:00510932010.015
male mating behaviorGO:0060179700.015
Fly
response to endogenous stimulusGO:00097191190.015
nucleobase containing small molecule metabolic processGO:00550861740.015
nucleoside phosphate metabolic processGO:00067531620.015
protein complex biogenesisGO:00702712010.015
positive regulation of sequestering of triglycerideGO:001089010.015
chaeta developmentGO:0022416970.015
histolysisGO:00075591020.015
cellular response to dna damage stimulusGO:00069742230.015
small gtpase mediated signal transductionGO:0007264880.015
positive regulation of cell motilityGO:200014730.015
ras protein signal transductionGO:0007265880.015
organelle assemblyGO:00709251980.015
immune response regulating signaling pathwayGO:000276420.015
response to copper ionGO:004668840.015
developmental pigmentationGO:0048066680.015
regulation of humoral immune responseGO:0002920510.015
photoreceptor cell differentiationGO:00465301700.015
enzyme linked receptor protein signaling pathwayGO:00071671790.015
regulation of response to biotic stimulusGO:0002831630.015
cellular response to organic substanceGO:00713101320.015
response to hexoseGO:000974630.015
epithelial cell developmentGO:00020642740.015
localization of cellGO:00516742570.015
deathGO:00162652840.015
drinking behaviorGO:004275620.015
courtship behaviorGO:0007619680.015
Fly
regulation of developmental growthGO:00486381740.015
regulation of organelle organizationGO:00330431960.015
aromatic compound catabolic processGO:00194391660.015
regulation of epithelial cell proliferationGO:005067840.015
locomotory behaviorGO:00076261760.015
cell motilityGO:00488702510.015
regulation of phosphorus metabolic processGO:00511742100.015
insecticide metabolic processGO:001714320.014
behavioral response to painGO:004826630.014
compound eye photoreceptor cell differentiationGO:00017511400.014
positive regulation of cell migrationGO:003033520.014
negative regulation of multicellular organismal processGO:00512411420.014
heterocycle catabolic processGO:00467001660.014
chemotaxisGO:00069352490.014
purine ribonucleotide metabolic processGO:00091501450.014
mesenchymal cell differentiationGO:004876210.014
maintenance of locationGO:0051235730.014
gene silencingGO:00164581380.014
peptide metabolic processGO:0006518800.014
vitamin metabolic processGO:000676620.014
neutral lipid catabolic processGO:004646130.014
detection of mechanical stimulus involved in sensory perception of painGO:005096620.014
respiratory system developmentGO:00605412130.014
circadian rhythmGO:00076231050.014
eye photoreceptor cell differentiationGO:00017541450.014
response to glucoseGO:000974920.014
blastoderm segmentationGO:00073501590.014
actin cytoskeleton organizationGO:00300362060.014
nucleotide metabolic processGO:00091171610.014
regulation of anatomical structure sizeGO:00900661630.014
chemical homeostasisGO:0048878920.014
hindbrain developmentGO:003090220.014
immune response activating signal transductionGO:000275720.014
regulation of cell developmentGO:00602842150.014
purine containing compound metabolic processGO:00725211550.014
aggressive behaviorGO:0002118630.014
purine nucleotide metabolic processGO:00061631460.014
transmembrane transportGO:00550851390.014
regulation of cell deathGO:00109411730.014
estrogen metabolic processGO:000821010.014
regulation of anatomical structure morphogenesisGO:00226032420.014
neuron projection guidanceGO:00974852410.014
feeding behaviorGO:0007631500.014
regulation of growthGO:00400082330.014
peptidyl proline modificationGO:001820830.014
cellular response to molecule of bacterial originGO:007121930.013
response to nitrogen compoundGO:1901698900.013
camera type eye morphogenesisGO:004859320.013
macromolecule catabolic processGO:00090571610.013
tissue deathGO:00162711020.013
endomembrane system organizationGO:00102561190.013
establishment of protein localizationGO:00451841630.013
response to organic cyclic compoundGO:0014070890.013
autophagic cell deathGO:0048102830.013
single organism intracellular transportGO:19025822070.013
regulation of lipid transportGO:003236830.013
regulation of catabolic processGO:00098941700.013
cellular macromolecule localizationGO:00707272200.013
chromosome segregationGO:00070591570.013
response to temperature stimulusGO:00092661060.013
monocarboxylic acid transportGO:001571830.013
cell cycle phase transitionGO:00447701400.013
chromatin modificationGO:00165681470.013
water homeostasisGO:003010430.013
cellular lipid metabolic processGO:0044255830.013
Fly
mating behaviorGO:00076171060.013
Fly
response to painGO:004826530.013
response to monosaccharideGO:003428440.013
axonogenesisGO:00074092900.013
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.013
regulation of phosphate metabolic processGO:00192202100.013
mitotic cell cycle phase transitionGO:00447721380.013
phosphatidic acid metabolic processGO:004647310.013
photoreceptor cell developmentGO:0042461960.013
intracellular transportGO:00469072280.013
cellular modified amino acid metabolic processGO:0006575450.013
protein complex assemblyGO:00064612000.013
columnar cuboidal epithelial cell developmentGO:00020662490.013
nephron developmentGO:007200630.013
regulation of nervous system developmentGO:00519602480.013
salivary gland cell autophagic cell deathGO:0035071830.013
agingGO:00075681430.013
response to starvationGO:0042594970.013
limb morphogenesisGO:003510810.013
mesenchymal cell developmentGO:001403110.013
cholesterol transportGO:003030120.013
lipopolysaccharide mediated signaling pathwayGO:003166310.013
cellular macromolecule catabolic processGO:00442651360.013
ribose phosphate metabolic processGO:00196931450.013
axis specificationGO:00097981670.013
carbohydrate derivative biosynthetic processGO:1901137850.013
meiotic cell cycle processGO:19030461320.013
actin filament based processGO:00300292200.012
cellular response to lipopolysaccharideGO:007122230.012
ribonucleotide metabolic processGO:00092591450.012
chromatin organizationGO:00063252070.012
cellular component assembly involved in morphogenesisGO:00109271510.012
regulation of gene expression epigeneticGO:00400291280.012
kidney epithelium developmentGO:007207330.012
ion homeostasisGO:0050801550.012
chromatin remodelingGO:0006338720.012
regulation of cell cycle processGO:00105641810.012
meiotic cell cycleGO:00513211710.012
rna processingGO:00063961470.012
wnt signaling pathwayGO:0016055980.012
nucleobase containing compound catabolic processGO:00346551650.012
cellular response to biotic stimulusGO:007121640.012
ovarian follicle cell developmentGO:00307072480.012
columnar cuboidal epithelial cell differentiationGO:00020652560.012
salivary gland histolysisGO:0035070880.012
regulation of cell proliferationGO:00421271630.012
stem cell divisionGO:0017145690.012
organonitrogen compound biosynthetic processGO:19015661170.012
posttranscriptional regulation of gene expressionGO:00106081450.012
regulation of programmed cell deathGO:00430671520.012
mitotic nuclear divisionGO:00070672130.012
embryonic morphogenesisGO:00485982060.012
embryonic development via the syncytial blastodermGO:00017001480.012
positive regulation of intracellular signal transductionGO:19025331160.012
toxin catabolic processGO:000940710.012
sulfur compound metabolic processGO:0006790590.012
protein heterooligomerizationGO:005129140.012
pigment metabolic processGO:0042440840.012
response to organonitrogen compoundGO:0010243750.012
anatomical structure homeostasisGO:0060249970.012
negative regulation of cell differentiationGO:00455961430.012
detection of external stimulusGO:0009581660.012
cellular response to oxygen containing compoundGO:1901701790.012
wound healing spreading of epidermal cellsGO:003531310.012
regulation of defense responseGO:00313471020.012
regulation of mitotic cell cycle phase transitionGO:19019901300.012
dendrite developmentGO:00163582040.012
positive regulation of transportGO:0051050920.012
olfactory behaviorGO:0042048970.012
membrane organizationGO:00610241120.012
positive regulation of cellular amine metabolic processGO:003324000.012
activation of innate immune responseGO:000221840.012
rna localizationGO:00064031150.012
synaptic transmissionGO:00072682880.012
l amino acid importGO:004309220.012
biological adhesionGO:00226101380.012
organophosphate catabolic processGO:00464341120.012
regulation of cellular localizationGO:00603411360.012
sensory perception of painGO:001923340.012
positive regulation of phosphorus metabolic processGO:00105621390.012
anterior posterior pattern specificationGO:00099521360.012
cellular protein localizationGO:00346131600.011
cellular amide metabolic processGO:0043603800.011
insecticide catabolic processGO:004670110.011
positive regulation of cellular amino acid metabolic processGO:004576400.011
cellular response to hexose stimulusGO:007133110.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.011
pattern recognition receptor signaling pathwayGO:000222120.011
response to alcoholGO:0097305950.011
Fly
cell adhesionGO:00071551360.011
pigment metabolic process involved in pigmentationGO:0043474330.011
somatic muscle developmentGO:0007525660.011
regulation of cellular catabolic processGO:00313291570.011
lauric acid metabolic processGO:004825210.011
innate immune response activating signal transductionGO:000275820.011
organonitrogen compound catabolic processGO:19015651280.011
hematopoietic progenitor cell differentiationGO:000224410.011
regulation of sterol transportGO:003237110.011
epiboly involved in wound healingGO:009050520.011
positive regulation of phosphate metabolic processGO:00459371390.011
dendrite morphogenesisGO:00488131990.011
protein transportGO:00150311550.011
protein processingGO:0016485680.011
dorsal ventral pattern formationGO:00099531330.011
glutathione metabolic processGO:0006749370.011
cellular homeostasisGO:0019725800.011
toxin metabolic processGO:000940420.011
kidney morphogenesisGO:006099330.011
protein phosphorylationGO:00064681690.011
single organism cellular localizationGO:19025801800.011
apoptotic processGO:00069151590.011
positive regulation of molecular functionGO:00440931360.011
organic hydroxy compound metabolic processGO:1901615830.011
synapse organizationGO:00508081960.011
regulation of notch signaling pathwayGO:00085931000.011
regulation of cell cycle phase transitionGO:19019871300.011
response to light stimulusGO:00094161240.011
spermatogenesisGO:00072832000.011
positive regulation of catalytic activityGO:00430851180.011
purine ribonucleoside metabolic processGO:00461281270.011
cell migrationGO:00164772380.011
tube morphogenesisGO:00352391910.011
regulation of ras protein signal transductionGO:0046578930.011
mitotic spindle organizationGO:00070522200.011
cell maturationGO:00484691440.011
spinal cord developmentGO:002151010.011
nephron tubule developmentGO:007208030.011
epibolyGO:009050420.011
cell recognitionGO:00080371020.011
neuropeptide signaling pathwayGO:0007218450.011
signal transduction by phosphorylationGO:00230141070.011
ribonucleoside metabolic processGO:00091191270.011
meiotic nuclear divisionGO:00071261510.011
central nervous system developmentGO:00074172010.011
nucleoside metabolic processGO:00091161270.011
regulation of cell substrate adhesionGO:001081020.010
positive regulation of developmental processGO:00510941430.010
pigment metabolic process involved in developmental pigmentationGO:0043324330.010
axon developmentGO:00615642970.010
detection of abiotic stimulusGO:0009582660.010
protein maturationGO:0051604710.010
cellular response to carbohydrate stimulusGO:007132240.010
response to mercury ionGO:004668930.010
secondary metabolite catabolic processGO:009048710.010
anterior posterior axis specification embryoGO:00085951030.010
response to woundingGO:0009611940.010
notch signaling pathwayGO:00072191200.010
digestive tract morphogenesisGO:00485461270.010
alditol phosphate metabolic processGO:005264620.010
male gamete generationGO:00482322010.010
regulation of proteolysisGO:0030162870.010
cellular response to water stimulusGO:007146220.010
dna metabolic processGO:00062592270.010
regulation of epithelial cell differentiationGO:003085640.010
ion transmembrane transportGO:00342201220.010
eye pigmentationGO:0048069430.010
regulation of mapk cascadeGO:0043408920.010
actin filament organizationGO:00070151260.010
chorion containing eggshell formationGO:00073041050.010
peptidyl amino acid modificationGO:00181931050.010
cellular macromolecular complex assemblyGO:00346221530.010
microtubule based movementGO:0007018510.010

Jhedup disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.071
nervous system diseaseDOID:86300.021
disease of metabolismDOID:001466700.021
urinary system diseaseDOID:1800.020
cardiovascular system diseaseDOID:128700.019
inherited metabolic disorderDOID:65500.017
acquired metabolic diseaseDOID:006015800.017
glucose metabolism diseaseDOID:419400.017
carbohydrate metabolism diseaseDOID:005001300.017
artery diseaseDOID:005082800.017
vascular diseaseDOID:17800.017
hypertensionDOID:1076300.017
diabetes mellitusDOID:935100.016
essential hypertensionDOID:1082500.016
type 2 diabetes mellitusDOID:935200.016
renal tubular transport diseaseDOID:44700.015
kidney diseaseDOID:55700.015
familial hypertriglyceridemiaDOID:005052700.014
lipid metabolism disorderDOID:314600.014
musculoskeletal system diseaseDOID:1700.014
integumentary system diseaseDOID:1600.012
hair diseaseDOID:42100.012
hypotrichosisDOID:453500.012
sensory system diseaseDOID:005015500.012
eye and adnexa diseaseDOID:149200.011
eye diseaseDOID:561400.010
disease of cellular proliferationDOID:1456600.010
cancerDOID:16200.010