Drosophila melanogaster

58 known processes

Jhe (Dmel_CG8425)

Juvenile hormone esterase

(Aliases: jhe,JHE,CG8425,Dmel\CG8425,JH,DmJhe)

Jhe biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
secondary metabolite biosynthetic processGO:0044550240.683
Fly
matingGO:00076181200.621
secondary metabolic processGO:0019748750.575
Fly
reproductive behaviorGO:00190981220.573
single organism behaviorGO:00447083910.396
response to alcoholGO:0097305950.373
male mating behaviorGO:0060179700.334
behavioral response to ethanolGO:0048149490.315
tissue migrationGO:00901301550.288
axon guidanceGO:00074112330.266
columnar cuboidal epithelial cell differentiationGO:00020652560.234
axon developmentGO:00615642970.232
response to ethanolGO:0045471590.219
taxisGO:00423303040.208
epithelium migrationGO:00901321480.186
response to insecticideGO:0017085140.176
ovarian follicle cell developmentGO:00307072480.168
ovarian follicle cell migrationGO:00072971210.157
hormone biosynthetic processGO:0042446200.152
Fly
epithelial cell migrationGO:00106311480.150
imaginal disc derived appendage developmentGO:00487373990.146
adult behaviorGO:00305341370.142
response to light stimulusGO:00094161240.142
ethanolamine containing compound metabolic processGO:004243940.140
response to oxygen containing compoundGO:19017002000.135
cell migrationGO:00164772380.131
mating behaviorGO:00076171060.131
acetylcholine metabolic processGO:000829120.125
neuron projection guidanceGO:00974852410.120
meiotic nuclear divisionGO:00071261510.115
response to organic substanceGO:00100332840.109
acetate ester metabolic processGO:190061920.108
neurotransmitter metabolic processGO:004213320.107
post embryonic appendage morphogenesisGO:00351203850.103
chemotaxisGO:00069352490.102
single organism biosynthetic processGO:00447112060.102
Fly
regulation of anatomical structure sizeGO:00900661630.099
defense response to other organismGO:00985422250.097
pheromone biosynthetic processGO:004281130.093
Fly
epithelial cell developmentGO:00020642740.090
response to external biotic stimulusGO:00432072930.087
acetylcholine catabolic processGO:000658110.087
response to other organismGO:00517072930.086
multi organism behaviorGO:00517051750.083
female meiotic divisionGO:0007143700.082
neuron recognitionGO:00080381010.082
meiotic cell cycleGO:00513211710.080
axonogenesisGO:00074092900.075
response to abiotic stimulusGO:00096283410.072
lauric acid metabolic processGO:004825210.071
appendage morphogenesisGO:00351073970.068
regulation of tube architecture open tracheal systemGO:0035152680.068
choline metabolic processGO:001969510.067
neurotransmitter catabolic processGO:004213510.067
amine catabolic processGO:000931010.067
insecticide metabolic processGO:001714320.065
cellular amine metabolic processGO:0044106120.062
lipid metabolic processGO:00066291210.061
imaginal disc derived wing morphogenesisGO:00074763370.060
response to biotic stimulusGO:00096072940.060
regionalizationGO:00030024160.060
skin developmentGO:0043588650.060
choline catabolic processGO:004242610.057
border follicle cell migrationGO:00072981130.056
imaginal disc derived appendage morphogenesisGO:00351143950.055
vesicle mediated transportGO:00161923810.052
wing disc morphogenesisGO:00074723440.052
localization of cellGO:00516742570.051
cell motilityGO:00488702510.051
ameboidal type cell migrationGO:00016671510.050
appendage developmentGO:00487364010.050
regulation of tube size open tracheal systemGO:0035151430.049
organonitrogen compound metabolic processGO:19015643180.049
male gamete generationGO:00482322010.047
response to organophosphorusGO:004668320.046
gland developmentGO:00487321910.045
negative regulation of cellular component organizationGO:00511291080.045
amine metabolic processGO:0009308120.045
programmed cell deathGO:00125012570.044
columnar cuboidal epithelial cell developmentGO:00020662490.043
response to radiationGO:00093141550.042
meiotic chromosome segregationGO:0045132590.042
aggressive behaviorGO:0002118630.042
response to mercury ionGO:004668930.041
cellular response to chemical stimulusGO:00708871990.040
defense responseGO:00069523000.039
small molecule metabolic processGO:00442813050.039
epithelial cell differentiationGO:00308553220.038
deathGO:00162652840.038
open tracheal system developmentGO:00074242040.038
steroid catabolic processGO:000670610.038
epidermis developmentGO:0008544650.037
response to starvationGO:0042594970.037
transition metal ion homeostasisGO:0055076170.037
cell deathGO:00082192790.036
positive regulation of signalingGO:00230562430.036
growthGO:00400073590.036
cellular biogenic amine catabolic processGO:004240210.035
protein localizationGO:00081042840.035
agingGO:00075681430.035
positive regulation of cell communicationGO:00106472500.034
transcription from rna polymerase ii promoterGO:00063663680.034
nuclear divisionGO:00002803320.034
insecticide catabolic processGO:004670110.034
respiratory system developmentGO:00605412130.034
regulation of cell developmentGO:00602842150.034
defense response to bacteriumGO:00427421780.034
regulation of multicellular organismal developmentGO:20000264140.033
axis specificationGO:00097981670.033
organelle fissionGO:00482853400.033
secondary metabolite catabolic processGO:009048710.033
circulatory system developmentGO:0072359820.032
regulation of neurogenesisGO:00507671580.032
positive regulation of nitrogen compound metabolic processGO:00511733540.032
vitamin biosynthetic processGO:000911010.032
meiotic cell cycle processGO:19030461320.032
spermatid differentiationGO:00485151140.032
apoptotic processGO:00069151590.032
cell recognitionGO:00080371020.032
regulation of immune system processGO:00026821760.031
dendrite morphogenesisGO:00488131990.031
negative regulation of response to stimulusGO:00485852580.030
biological adhesionGO:00226101380.030
carboxylic acid metabolic processGO:0019752920.030
xenobiotic catabolic processGO:004217810.030
negative regulation of cell communicationGO:00106482230.029
positive regulation of response to stimulusGO:00485843230.029
multicellular organismal agingGO:00102591400.029
positive regulation of macromolecule biosynthetic processGO:00105572830.029
regulation of intracellular signal transductionGO:19025312360.029
establishment of localization in cellGO:00516494020.028
response to bacteriumGO:00096171980.028
negative regulation of gene expressionGO:00106293870.028
endocytosisGO:00068973100.028
homeostatic processGO:00425921990.028
phosphatidic acid metabolic processGO:004647310.028
organic hydroxy compound metabolic processGO:1901615830.028
phagocytosisGO:00069092150.028
establishment of blood nerve barrierGO:000806520.028
positive regulation of nucleobase containing compound metabolic processGO:00459353320.028
cellular amino acid metabolic processGO:0006520610.027
regulation of programmed cell deathGO:00430671520.027
regulation of organelle organizationGO:00330431960.027
single organism catabolic processGO:00447122280.027
organophosphate metabolic processGO:00196371950.026
cell proliferationGO:00082832990.026
polyol biosynthetic processGO:004617330.025
positive regulation of macromolecule metabolic processGO:00106044050.025
regulation of transcription from rna polymerase ii promoterGO:00063573780.025
motor neuron axon guidanceGO:0008045580.025
oxoacid metabolic processGO:00434361030.025
multi multicellular organism processGO:00447061230.025
synaptic transmissionGO:00072682880.024
phototaxisGO:0042331210.024
organic substance catabolic processGO:19015753080.024
organic acid metabolic processGO:00060821030.024
positive regulation of cellular component organizationGO:00511301560.024
regulation of cell cycleGO:00517262910.024
maintenance of locationGO:0051235730.024
organonitrogen compound catabolic processGO:19015651280.023
peripheral nervous system developmentGO:0007422520.023
cellular response to heatGO:0034605240.023
regulation of nervous system developmentGO:00519602480.023
embryonic development via the syncytial blastodermGO:00017001480.023
regulation of response to stressGO:00801342000.023
protein modification processGO:00362114380.023
regulation of phosphorus metabolic processGO:00511742100.023
positive regulation of signal transductionGO:00099672230.023
actin cytoskeleton organizationGO:00300362060.022
cellular response to external stimulusGO:0071496660.022
regulation of cell differentiationGO:00455953020.022
cellular ketone metabolic processGO:0042180240.022
immune responseGO:00069552460.022
blastoderm segmentationGO:00073501590.022
toxin catabolic processGO:000940710.022
regulation of cellular amine metabolic processGO:003323830.022
positive regulation of biosynthetic processGO:00098913160.022
epidermal cell differentiationGO:0009913510.022
ras protein signal transductionGO:0007265880.022
regulation of cellular ketone metabolic processGO:001056530.021
immune system processGO:00023763470.021
septate junction assemblyGO:0019991260.021
stem cell proliferationGO:0072089880.021
intracellular signal transductionGO:00355563000.021
apical junction assemblyGO:0043297320.021
regulation of apoptotic processGO:00429811300.021
eye developmentGO:00016543230.021
male courtship behavior veined wing generated song productionGO:0045433200.021
actin filament based processGO:00300292200.021
regulation of cellular amino acid metabolic processGO:000652100.021
organelle assemblyGO:00709251980.021
phosphorylationGO:00163102940.021
cell junction assemblyGO:0034329420.021
macromolecular complex assemblyGO:00650032560.021
cellular hormone metabolic processGO:0034754230.021
secretion by cellGO:00329401010.021
negative regulation of nucleic acid templated transcriptionGO:19035072400.021
response to copper ionGO:004668840.020
cell cell junction organizationGO:0045216550.020
signal releaseGO:0023061490.020
lipid homeostasisGO:0055088330.020
dendrite developmentGO:00163582040.020
negative regulation of signal transductionGO:00099682060.020
negative regulation of macromolecule biosynthetic processGO:00105582700.020
enzyme linked receptor protein signaling pathwayGO:00071671790.020
cellular catabolic processGO:00442483720.020
regulation of anatomical structure morphogenesisGO:00226032420.020
exocrine system developmentGO:00352721620.020
cellular protein modification processGO:00064644380.020
hair cell differentiationGO:0035315470.020
chaeta developmentGO:0022416970.019
anion homeostasisGO:005508130.019
regulation of behaviorGO:0050795750.019
regulation of tube sizeGO:0035150460.019
rho protein signal transductionGO:0007266140.019
sensory perception of smellGO:0007608800.019
response to nutrient levelsGO:00316671140.019
cell maturationGO:00484691440.019
response to organic cyclic compoundGO:0014070890.019
actin filament organizationGO:00070151260.019
response to paraquatGO:190156240.019
cellular response to dna damage stimulusGO:00069742230.019
negative regulation of nitrogen compound metabolic processGO:00511722650.019
cell junction organizationGO:0034330570.019
response to toxic substanceGO:0009636220.019
regulation of cell deathGO:00109411730.019
locomotory behaviorGO:00076261760.018
chromosome segregationGO:00070591570.018
carbohydrate derivative metabolic processGO:19011352170.018
cell divisionGO:00513012480.018
medium chain fatty acid metabolic processGO:005179110.018
negative regulation of cellular metabolic processGO:00313243820.018
positive regulation of cellular biosynthetic processGO:00313283160.018
regulation of cell morphogenesisGO:00226041630.018
cell adhesion involved in heart morphogenesisGO:0061343120.018
response to woundingGO:0009611940.018
spindle organizationGO:00070512530.018
positive regulation of rna biosynthetic processGO:19026802660.018
salivary gland developmentGO:00074311620.018
regulation of cell projection organizationGO:0031344920.018
catabolic processGO:00090564090.018
tergite morphogenesisGO:000749010.017
negative regulation of cellular biosynthetic processGO:00313272770.017
positive regulation of gene expressionGO:00106282900.017
regulation of neurotransmitter levelsGO:0001505380.017
regulation of cell proliferationGO:00421271630.017
segmentationGO:00352822070.017
negative regulation of biosynthetic processGO:00098902770.017
negative regulation of programmed cell deathGO:0043069720.017
protein complex biogenesisGO:00702712010.017
digestive tract developmentGO:00485651490.017
negative regulation of transcription dna templatedGO:00458922370.017
fat soluble vitamin biosynthetic processGO:004236210.017
nucleoside phosphate metabolic processGO:00067531620.016
regulation of catalytic activityGO:00507901850.016
regulation of neuron projection developmentGO:0010975690.016
gland morphogenesisGO:00226121450.016
salivary gland morphogenesisGO:00074351450.016
camera type eye developmentGO:004301040.016
regulation of ras protein signal transductionGO:0046578930.016
developmental growthGO:00485892800.016
vitamin metabolic processGO:000676620.016
positive regulation of nervous system developmentGO:0051962690.016
cellular macromolecule localizationGO:00707272200.016
regulation of localizationGO:00328792750.016
cellular response to organic substanceGO:00713101320.016
negative regulation of signalingGO:00230572190.016
regulation of growthGO:00400082330.016
positive regulation of rna metabolic processGO:00512542710.016
organic substance transportGO:00717022570.016
embryo development ending in birth or egg hatchingGO:00097921520.016
small gtpase mediated signal transductionGO:0007264880.016
positive regulation of nucleic acid templated transcriptionGO:19035082660.016
cuticle developmentGO:0042335860.016
spermatogenesisGO:00072832000.015
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.015
alcohol metabolic processGO:0006066250.015
organic cyclic compound catabolic processGO:19013611680.015
positive regulation of intracellular signal transductionGO:19025331160.015
negative regulation of rna biosynthetic processGO:19026792400.015
positive regulation of phosphorus metabolic processGO:00105621390.015
toxin metabolic processGO:000940420.015
negative regulation of organelle organizationGO:0010639560.015
maintenance of imaginal disc derived wing hair orientationGO:003532130.015
anterior posterior pattern specificationGO:00099521360.015
protein complex assemblyGO:00064612000.015
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.015
regulation of phosphate metabolic processGO:00192202100.015
compound eye morphogenesisGO:00017452490.015
fat soluble vitamin metabolic processGO:000677510.014
male courtship behavior veined wing vibrationGO:0016545210.014
regulation of molecular functionGO:00650092170.014
developmental programmed cell deathGO:00106231380.014
negative regulation of developmental processGO:00510932010.014
dorsal ventral axis specificationGO:0009950660.014
response to extracellular stimulusGO:00099911160.014
lipid biosynthetic processGO:0008610460.014
digestive tract morphogenesisGO:00485461270.014
response to lipopolysaccharideGO:003249640.014
muscle structure developmentGO:00610612240.014
female meiosis chromosome segregationGO:0016321330.014
synaptic target recognitionGO:0008039450.014
energy taxisGO:0009453210.014
cellular response to ethanolGO:007136140.014
compound eye developmentGO:00487493070.014
head developmentGO:00603221350.014
cell adhesionGO:00071551360.014
regulation of protein metabolic processGO:00512462560.014
estrogen metabolic processGO:000821010.014
organic hydroxy compound catabolic processGO:190161640.014
regulation of developmental growthGO:00486381740.014
positive regulation of cell migrationGO:003033520.014
tube developmentGO:00352952440.014
mapk cascadeGO:00001651070.013
ecdysteroid metabolic processGO:0045455190.013
developmental maturationGO:00217001720.013
body morphogenesisGO:001017120.013
innate immune responseGO:00450871440.013
digestive system developmentGO:00551231490.013
tripartite regional subdivisionGO:00073511030.013
regulation of lipid transportGO:003236830.013
regulation of phosphorylationGO:00423251470.013
locomotor rhythmGO:0045475560.013
response to lipidGO:0033993380.013
positive regulation of transcription dna templatedGO:00458932660.013
regulation of epithelial cell proliferationGO:005067840.013
sensory perception of chemical stimulusGO:00076061160.013
sterol homeostasisGO:005509240.013
aromatic compound catabolic processGO:00194391660.013
response to endogenous stimulusGO:00097191190.013
sensory organ morphogenesisGO:00905962600.013
ecdysteroid biosynthetic processGO:0045456150.013
nucleotide metabolic processGO:00091171610.013
negative regulation of apoptotic processGO:0043066630.013
courtship behaviorGO:0007619680.013
Fly
determination of adult lifespanGO:00083401370.013
eye morphogenesisGO:00485922600.013
mitochondrion organizationGO:0007005650.013
cellular response to mechanical stimulusGO:007126020.013
sensory perceptionGO:00076001960.013
anterior posterior axis specification embryoGO:00085951030.013
secretionGO:00469031090.012
regulation of mapk cascadeGO:0043408920.012
endomembrane system organizationGO:00102561190.012
cellular protein localizationGO:00346131600.012
histolysisGO:00075591020.012
positive regulation of phosphate metabolic processGO:00459371390.012
tissue deathGO:00162711020.012
nucleobase containing small molecule metabolic processGO:00550861740.012
positive regulation of defense responseGO:0031349590.012
response to heatGO:0009408630.012
peptidyl amino acid modificationGO:00181931050.012
response to monosaccharideGO:003428440.012
connective tissue developmentGO:006144830.012
embryonic axis specificationGO:00005781070.012
cellular macromolecule catabolic processGO:00442651360.012
regulation of cellular component sizeGO:0032535980.012
intracellular transportGO:00469072280.012
cellular nitrogen compound catabolic processGO:00442701650.012
positive regulation of cell motilityGO:200014730.012
cellular lipid metabolic processGO:0044255830.012
lipid catabolic processGO:0016042210.012
negative regulation of cellular protein metabolic processGO:0032269850.012
positive regulation of phosphorylationGO:0042327870.012
regulation of axonogenesisGO:0050770320.012
macromolecule catabolic processGO:00090571610.012
cellular response to oxidative stressGO:0034599280.012
regulation of cell sizeGO:0008361630.011
imaginal disc pattern formationGO:0007447910.011
response to inorganic substanceGO:0010035440.011
dorsal ventral pattern formationGO:00099531330.011
cellular response to oxygen containing compoundGO:1901701790.011
response to oxygen levelsGO:0070482590.011
positive regulation of molecular functionGO:00440931360.011
cell growthGO:00160491080.011
cellular response to biotic stimulusGO:007121640.011
salivary gland cell autophagic cell deathGO:0035071830.011
regulation of cellular protein metabolic processGO:00322682430.011
defense response to gram negative bacteriumGO:0050829940.011
negative regulation of nucleobase containing compound metabolic processGO:00459342610.011
negative regulation of rna metabolic processGO:00512532510.011
protein phosphorylationGO:00064681690.011
proximal distal pattern formationGO:0009954150.011
neuromuscular junction developmentGO:00075281490.011
regulation of cellular localizationGO:00603411360.011
transition metal ion transportGO:0000041160.011
positive regulation of catalytic activityGO:00430851180.011
hormone metabolic processGO:0042445330.011
positive regulation of cell developmentGO:0010720610.011
response to nitrogen compoundGO:1901698900.011
heterocycle catabolic processGO:00467001660.011
negative chemotaxisGO:0050919150.011
male courtship behaviorGO:0008049630.011
circadian behaviorGO:0048512760.011
positive regulation of neurogenesisGO:0050769410.011
chromosome organizationGO:00512763600.011
cellular component assembly involved in morphogenesisGO:00109271510.011
response to glucoseGO:000974920.011
regulation of neuron differentiationGO:00456641030.011
positive regulation of cell differentiationGO:0045597640.011
nucleobase containing compound catabolic processGO:00346551650.011
limb developmentGO:006017310.011
organonitrogen compound biosynthetic processGO:19015661170.011
regulation of small gtpase mediated signal transductionGO:0051056930.011
dorsal closureGO:0007391790.011
cellular response to nutrient levelsGO:0031669620.011
purine containing compound metabolic processGO:00725211550.011
cellular response to endogenous stimulusGO:0071495800.010
male courtship behavior veined wing extensionGO:0048065220.010
establishment of protein localizationGO:00451841630.010
chitin based cuticle developmentGO:0040003490.010
cation transmembrane transportGO:0098655880.010
regulation of defense responseGO:00313471020.010
retina development in camera type eyeGO:006004140.010
glycerolipid metabolic processGO:0046486340.010
purine ribonucleoside metabolic processGO:00461281270.010
signal transduction by phosphorylationGO:00230141070.010
muscle organ developmentGO:00075171270.010
monocarboxylic acid transportGO:001571830.010
wing disc pattern formationGO:0035222660.010
antimicrobial humoral responseGO:0019730990.010

Jhe disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.032
artery diseaseDOID:005082800.027
cardiovascular system diseaseDOID:128700.027
hypertensionDOID:1076300.027
vascular diseaseDOID:17800.027
essential hypertensionDOID:1082500.022
disease of metabolismDOID:001466700.019
carbohydrate metabolism diseaseDOID:005001300.017
glucose metabolism diseaseDOID:419400.017
acquired metabolic diseaseDOID:006015800.017
nervous system diseaseDOID:86300.013
inherited metabolic disorderDOID:65500.012