IMP: Integrative Multi-species Prediction

Drosophila melanogaster

400 known processes

EcR (Dmel_CG1765)

Ecdysone receptor

(Aliases: dmEcR,Dhr23,EcR-B1,lie,ms(2)42A,Dmel\CG1765,EcRB1,ECR,EcdR,NR1H1,Ecr,CG8347,EcR-A,EcR-B,ms(2)06410,ecr,DmEcR,anon-WO0229075.1,snt,EcRB-1,DEcR,CG1765,dECR)

Entrez: 35540
FLYBASE: FBgn0000546
UniProtKB: A4UZ51
UniProtKB: P34021
UniProtKB: E1JGY2

Process Predictions
Disease Predictions

EcR biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
epithelial cell migration	GO:0010631	148	1.000
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.999
epithelium migration	GO:0090132	148	0.999
ovarian follicle cell development	GO:0030707	248	0.999
growth	GO:0040007	359	0.999
male gamete generation	GO:0048232	201	0.998
wing disc morphogenesis	GO:0007472	344	0.998
response to organic substance	GO:0010033	284	0.997
cellular response to chemical stimulus	GO:0070887	199	0.997
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.996
regulation of growth	GO:0040008	233	0.996
developmental growth	GO:0048589	280	0.995
tissue migration	GO:0090130	155	0.994
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.993
cellular catabolic process	GO:0044248	372	0.993
aging	GO:0007568	143	0.991
ovarian follicle cell migration	GO:0007297	121	0.990
columnar cuboidal epithelial cell development	GO:0002066	249	0.989
transcription from rna polymerase ii promoter	GO:0006366	368	0.988
response to wounding	GO:0009611	94	0.988
positive regulation of growth	GO:0045927	75	0.987
secretion	GO:0046903	109	0.987
catabolic process	GO:0009056	409	0.986
regulation of cell death	GO:0010941	173	0.986
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.986
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.985
negative regulation of cell communication	GO:0010648	223	0.985
tissue morphogenesis	GO:0048729	297	0.984
axon guidance	GO:0007411	233	0.984
spermatogenesis	GO:0007283	200	0.984
tube development	GO:0035295	244	0.981
regulation of nervous system development	GO:0051960	248	0.980
cuticle development	GO:0042335	86	0.980
learning	GO:0007612	75	0.979
positive regulation of rna metabolic process	GO:0051254	271	0.978
regulation of muscle organ development	GO:0048634	13	0.974
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.973
positive regulation of multicellular organismal process	GO:0051240	143	0.971
response to external biotic stimulus	GO:0043207	293	0.970
regulation of localization	GO:0032879	275	0.969
regulation of developmental growth	GO:0048638	174	0.968
cognition	GO:0050890	141	0.968
establishment of localization in cell	GO:0051649	402	0.960
striated muscle tissue development	GO:0014706	27	0.959
positive regulation of macromolecule metabolic process	GO:0010604	405	0.957
regulation of circadian sleep wake cycle sleep	GO:0045187	21	0.956
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.955
rhythmic process	GO:0048511	106	0.954
positive regulation of biosynthetic process	GO:0009891	316	0.947
positive regulation of rna biosynthetic process	GO:1902680	266	0.946
gland development	GO:0048732	191	0.945
appendage development	GO:0048736	401	0.943
protein catabolic process	GO:0030163	101	0.943
negative regulation of signaling	GO:0023057	219	0.942
respiratory system development	GO:0060541	213	0.942
morphogenesis of an epithelium	GO:0002009	276	0.936
response to hypoxia	GO:0001666	53	0.935
regulation of protein metabolic process	GO:0051246	256	0.931
axonogenesis	GO:0007409	290	0.930
border follicle cell migration	GO:0007298	113	0.927
muscle organ development	GO:0007517	127	0.921
cell migration	GO:0016477	238	0.919
circadian rhythm	GO:0007623	105	0.919
axon development	GO:0061564	297	0.918
mushroom body development	GO:0016319	70	0.914
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.912
learning or memory	GO:0007611	141	0.911
post embryonic appendage morphogenesis	GO:0035120	385	0.910
intracellular transport	GO:0046907	228	0.909
regulation of neurogenesis	GO:0050767	158	0.904
regulation of cell morphogenesis	GO:0022604	163	0.899
gland morphogenesis	GO:0022612	145	0.894
cell motility	GO:0048870	251	0.893
muscle tissue development	GO:0060537	30	0.892
response to reactive oxygen species	GO:0000302	24	0.890
taxis	GO:0042330	304	0.889
epithelial cell development	GO:0002064	274	0.881
ameboidal type cell migration	GO:0001667	151	0.878
regulation of cellular localization	GO:0060341	136	0.878
exocrine system development	GO:0035272	162	0.866
cellular response to organic substance	GO:0071310	132	0.864
body morphogenesis	GO:0010171	2	0.862	Worm
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.859
secretion by cell	GO:0032940	101	0.858
negative regulation of rna biosynthetic process	GO:1902679	240	0.856
regulation of hormone levels	GO:0010817	40	0.855
cellular response to oxygen containing compound	GO:1901701	79	0.844
negative regulation of transcription dna templated	GO:0045892	237	0.842
developmental programmed cell death	GO:0010623	138	0.839
positive regulation of transcription dna templated	GO:0045893	266	0.837
positive regulation of cellular biosynthetic process	GO:0031328	316	0.830
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.827
response to alcohol	GO:0097305	95	0.825
single organism behavior	GO:0044708	391	0.820
negative regulation of developmental process	GO:0051093	201	0.816
death	GO:0016265	284	0.816
positive regulation of developmental growth	GO:0048639	62	0.814
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.813
circadian behavior	GO:0048512	76	0.806
chemotaxis	GO:0006935	249	0.801
determination of adult lifespan	GO:0008340	137	0.798
regeneration	GO:0031099	16	0.794
regulation of cell proliferation	GO:0042127	163	0.790
regulation of anatomical structure morphogenesis	GO:0022603	242	0.781
translation	GO:0006412	69	0.777
stem cell division	GO:0017145	69	0.777
negative regulation of cellular metabolic process	GO:0031324	382	0.770
response to nutrient levels	GO:0031667	114	0.762
developmental maturation	GO:0021700	172	0.756
central nervous system development	GO:0007417	201	0.756
urogenital system development	GO:0001655	72	0.733
positive regulation of response to stimulus	GO:0048584	323	0.733
organic substance catabolic process	GO:1901575	308	0.731
response to bacterium	GO:0009617	198	0.729
imaginal disc derived wing morphogenesis	GO:0007476	337	0.728
salivary gland development	GO:0007431	162	0.724
response to oxygen containing compound	GO:1901700	200	0.722
chorion containing eggshell formation	GO:0007304	105	0.717
positive regulation of developmental process	GO:0051094	143	0.716
reproductive system development	GO:0061458	74	0.702
multicellular organismal reproductive behavior	GO:0033057	110	0.701	Worm
neuron projection guidance	GO:0097485	241	0.697
neurological system process	GO:0050877	358	0.686
immune response	GO:0006955	246	0.685
cell proliferation	GO:0008283	299	0.680
imaginal disc derived appendage development	GO:0048737	399	0.678
embryonic development via the syncytial blastoderm	GO:0001700	148	0.673
epithelial tube morphogenesis	GO:0060562	88	0.670
synapse assembly	GO:0007416	143	0.668
defense response	GO:0006952	300	0.654
memory	GO:0007613	94	0.649
response to endogenous stimulus	GO:0009719	119	0.634
immune system process	GO:0002376	347	0.633
regulation of cell adhesion	GO:0030155	27	0.631
cytoplasmic transport	GO:0016482	130	0.627
regulation of mitotic cell cycle	GO:0007346	190	0.623
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	38	0.611
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.600
extracellular structure organization	GO:0043062	46	0.600
response to decreased oxygen levels	GO:0036293	58	0.592
regulation of transport	GO:0051049	181	0.591
negative regulation of cellular biosynthetic process	GO:0031327	277	0.590
spermatid development	GO:0007286	98	0.586
malpighian tubule morphogenesis	GO:0007443	44	0.580
salivary gland morphogenesis	GO:0007435	145	0.576
protein targeting to nucleus	GO:0044744	51	0.573
organ growth	GO:0035265	56	0.571
regulation of programmed cell death	GO:0043067	152	0.571
regulation of cellular catabolic process	GO:0031329	157	0.569
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	65	0.565
positive regulation of cell differentiation	GO:0045597	64	0.562
organelle fission	GO:0048285	340	0.561
macromolecule catabolic process	GO:0009057	161	0.560
regulation of defense response	GO:0031347	102	0.559
oocyte differentiation	GO:0009994	145	0.556
response to biotic stimulus	GO:0009607	294	0.547
negative regulation of cell proliferation	GO:0008285	69	0.546
response to ecdysone	GO:0035075	34	0.542
synaptic transmission	GO:0007268	288	0.534
negative regulation of signal transduction	GO:0009968	206	0.533
organelle assembly	GO:0070925	198	0.532
regulation of translation	GO:0006417	56	0.525
germarium derived egg chamber formation	GO:0007293	101	0.520
anterior posterior axis specification embryo	GO:0008595	103	0.518
dendrite morphogenesis	GO:0048813	199	0.514
protein import	GO:0017038	55	0.513
negative regulation of biosynthetic process	GO:0009890	277	0.512
cell type specific apoptotic process	GO:0097285	38	0.511
response to sterol	GO:0036314	34	0.511
single organismal cell cell adhesion	GO:0016337	45	0.508
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.508
male mating behavior	GO:0060179	70	0.504	Worm
hormone metabolic process	GO:0042445	33	0.500
neural precursor cell proliferation	GO:0061351	75	0.498
positive regulation of gene expression	GO:0010628	290	0.491
embryo development ending in birth or egg hatching	GO:0009792	152	0.487
response to other organism	GO:0051707	293	0.486
open tracheal system development	GO:0007424	204	0.485
segmentation	GO:0035282	207	0.482
regulation of cellular component biogenesis	GO:0044087	201	0.479
skeletal muscle organ development	GO:0060538	48	0.475
positive regulation of signaling	GO:0023056	243	0.474
negative regulation of catabolic process	GO:0009895	36	0.473
negative regulation of gene expression	GO:0010629	387	0.467
regulation of behavior	GO:0050795	75	0.457
single organism nuclear import	GO:1902593	51	0.451
circadian sleep wake cycle	GO:0042745	28	0.448
regulation of catabolic process	GO:0009894	170	0.447
organic substance transport	GO:0071702	257	0.438
regulation of multicellular organismal development	GO:2000026	414	0.431
skeletal muscle tissue development	GO:0007519	13	0.421
response to oxygen levels	GO:0070482	59	0.420
homeostatic process	GO:0042592	199	0.414	Worm
negative regulation of wnt signaling pathway	GO:0030178	28	0.412
pericardium development	GO:0060039	2	0.411
instar larval development	GO:0002168	55	0.406
biological adhesion	GO:0022610	138	0.404
tissue death	GO:0016271	102	0.397
positive regulation of cell communication	GO:0010647	250	0.395
protein import into nucleus	GO:0006606	51	0.392
cell growth	GO:0016049	108	0.388
negative regulation of growth	GO:0045926	84	0.387
negative regulation of rna metabolic process	GO:0051253	251	0.384
germ line stem cell division	GO:0042078	25	0.376
regulation of striated muscle tissue development	GO:0016202	5	0.371
stem cell differentiation	GO:0048863	117	0.369
posttranscriptional regulation of gene expression	GO:0010608	145	0.366
positive regulation of cell migration	GO:0030335	2	0.366
regulation of intracellular transport	GO:0032386	64	0.361
positive regulation of wnt signaling pathway	GO:0030177	25	0.360
sleep	GO:0030431	49	0.359
regionalization	GO:0003002	416	0.354
cell cycle g1 s phase transition	GO:0044843	31	0.353
regulation of protein transport	GO:0051223	57	0.352
regulation of cell cycle	GO:0051726	291	0.352
blastoderm segmentation	GO:0007350	159	0.347
salivary gland histolysis	GO:0035070	88	0.347
positive regulation of behavior	GO:0048520	19	0.344
response to growth factor	GO:0070848	31	0.342
male sex differentiation	GO:0046661	25	0.341
negative regulation of cell differentiation	GO:0045596	143	0.339
pericardium morphogenesis	GO:0003344	2	0.338
tripartite regional subdivision	GO:0007351	103	0.331
response to ketone	GO:1901654	34	0.328
nucleocytoplasmic transport	GO:0006913	72	0.328
protein localization to nucleus	GO:0034504	55	0.325
regulation of cell motility	GO:2000145	23	0.324
response to ethanol	GO:0045471	59	0.322
single organism intracellular transport	GO:1902582	207	0.318
regulation of glial cell proliferation	GO:0060251	11	0.316
brain development	GO:0007420	120	0.308
cellular response to endogenous stimulus	GO:0071495	80	0.306
dorsal appendage formation	GO:0046843	47	0.302
oocyte development	GO:0048599	124	0.294
defense response to bacterium	GO:0042742	178	0.291
response to oxidative stress	GO:0006979	86	0.283
circadian sleep wake cycle process	GO:0022410	24	0.282
multicellular organismal aging	GO:0010259	140	0.282
cell fate determination	GO:0001709	91	0.277
nuclear import	GO:0051170	51	0.273
muscle structure development	GO:0061061	224	0.269
synapse organization	GO:0050808	196	0.267
negative regulation of response to stimulus	GO:0048585	258	0.266
germ band shortening	GO:0007390	19	0.263
olfactory behavior	GO:0042048	97	0.260
axis specification	GO:0009798	167	0.257
cellular protein catabolic process	GO:0044257	83	0.255
response to extracellular stimulus	GO:0009991	116	0.253
positive regulation of catalytic activity	GO:0043085	118	0.252
cellular macromolecule catabolic process	GO:0044265	136	0.251
reproductive structure development	GO:0048608	74	0.249
regulation of neural precursor cell proliferation	GO:2000177	35	0.247
positive regulation of signal transduction	GO:0009967	223	0.245
regulation of lipid metabolic process	GO:0019216	15	0.244
regulation of secretion	GO:0051046	44	0.236
protein modification process	GO:0036211	438	0.235
dorsal vessel heart proper cell fate commitment	GO:0035053	2	0.234
response to lipid	GO:0033993	38	0.230
lipid metabolic process	GO:0006629	121	0.229
synaptic growth at neuromuscular junction	GO:0051124	119	0.227
monocarboxylic acid metabolic process	GO:0032787	29	0.225
positive regulation of cell development	GO:0010720	61	0.224
response to organic cyclic compound	GO:0014070	89	0.224
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.221
regulation of pathway restricted smad protein phosphorylation	GO:0060393	1	0.218
stem cell proliferation	GO:0072089	88	0.216
spermatid differentiation	GO:0048515	114	0.213
positive regulation of transport	GO:0051050	92	0.211
cellular component assembly involved in morphogenesis	GO:0010927	151	0.211
regulation of catalytic activity	GO:0050790	185	0.210
morphogenesis of follicular epithelium	GO:0016333	36	0.209
cell death	GO:0008219	279	0.209
negative regulation of multicellular organismal process	GO:0051241	142	0.208
negative regulation of cell cycle phase transition	GO:1901988	103	0.207
renal tubule development	GO:0061326	64	0.204
regulation of protein localization	GO:0032880	76	0.200
regulation of intracellular protein transport	GO:0033157	46	0.198
positive regulation of lipid biosynthetic process	GO:0046889	3	0.197
g1 s transition of mitotic cell cycle	GO:0000082	31	0.187
cell division	GO:0051301	248	0.186
response to abiotic stimulus	GO:0009628	341	0.184
regulation of apoptotic process	GO:0042981	130	0.182
eggshell formation	GO:0030703	105	0.182
extrinsic apoptotic signaling pathway	GO:0097191	1	0.181
nuclear transport	GO:0051169	72	0.180
sex differentiation	GO:0007548	81	0.178
response to nitrogen compound	GO:1901698	90	0.177
dormancy process	GO:0022611	2	0.177
cell competition in a multicellular organism	GO:0035212	10	0.176
purine ribonucleotide metabolic process	GO:0009150	145	0.175
lipid localization	GO:0010876	54	0.171	Worm
regulation of cysteine type endopeptidase activity	GO:2000116	27	0.170
cell recognition	GO:0008037	102	0.167
induction of programmed cell death by hormones	GO:0035081	12	0.164
circulatory system process	GO:0003013	37	0.164
mesoderm morphogenesis	GO:0048332	22	0.161
dorsal closure	GO:0007391	79	0.160
positive regulation of nucleotide metabolic process	GO:0045981	55	0.160
regulation of establishment of protein localization	GO:0070201	61	0.160
protein transport	GO:0015031	155	0.157
cellular lipid metabolic process	GO:0044255	83	0.154
blood circulation	GO:0008015	26	0.152
meiotic cell cycle	GO:0051321	171	0.151
positive regulation of pathway restricted smad protein phosphorylation	GO:0010862	1	0.151
protein complex assembly	GO:0006461	200	0.150
positive regulation of nervous system development	GO:0051962	69	0.150
negative regulation of molecular function	GO:0044092	51	0.149
positive regulation of programmed cell death	GO:0043068	62	0.147
regulation of cell development	GO:0060284	215	0.146
tube morphogenesis	GO:0035239	191	0.145
positive regulation of cellular response to insulin stimulus	GO:1900078	4	0.144
molting cycle chitin based cuticle	GO:0007591	56	0.142
endocytosis	GO:0006897	310	0.142
cell activation	GO:0001775	9	0.140
programmed cell death	GO:0012501	257	0.139
positive regulation of cell motility	GO:2000147	3	0.139
cellular response to extracellular stimulus	GO:0031668	64	0.138
negative regulation of programmed cell death	GO:0043069	72	0.137
genital disc development	GO:0035215	44	0.137
positive regulation of phosphorus metabolic process	GO:0010562	139	0.136
germarium derived oocyte fate determination	GO:0007294	26	0.136
positive regulation of molecular function	GO:0044093	136	0.134
r3 r4 cell fate commitment	GO:0007464	10	0.134
regulation of molecular function	GO:0065009	217	0.132
cellular response to dna damage stimulus	GO:0006974	223	0.129
immune effector process	GO:0002252	98	0.128
adherens junction organization	GO:0034332	27	0.128
response to glucose	GO:0009749	2	0.126
cell adhesion	GO:0007155	136	0.125
peptidyl tyrosine modification	GO:0018212	24	0.122
regulation of response to external stimulus	GO:0032101	115	0.122
apoptotic process involved in morphogenesis	GO:0060561	3	0.121
positive regulation of cellular catabolic process	GO:0031331	95	0.120
single organism cellular localization	GO:1902580	180	0.119
regulation of hydrolase activity	GO:0051336	97	0.116
peptidyl threonine phosphorylation	GO:0018107	2	0.116
regulation of imaginal disc growth	GO:0045570	26	0.113
positive regulation of neurogenesis	GO:0050769	41	0.112
positive regulation of response to external stimulus	GO:0032103	44	0.112
eye morphogenesis	GO:0048592	260	0.112
anterior posterior axis specification	GO:0009948	109	0.111
actin filament organization	GO:0007015	126	0.111
localization of cell	GO:0051674	257	0.111
germarium derived female germ line cyst formation	GO:0030727	42	0.110
protein localization	GO:0008104	284	0.108
establishment of protein localization	GO:0045184	163	0.108
digestive system development	GO:0055123	149	0.107
camera type eye development	GO:0043010	4	0.105
organonitrogen compound metabolic process	GO:1901564	318	0.103
positive regulation of catabolic process	GO:0009896	105	0.103
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.103
entry into diapause	GO:0055115	1	0.103
striated muscle cell differentiation	GO:0051146	90	0.102
regulation of cell shape	GO:0008360	113	0.102
response to temperature stimulus	GO:0009266	106	0.101
regulation of cytoplasmic transport	GO:1903649	47	0.101
regulation of locomotion	GO:0040012	42	0.101
regulation of neuron apoptotic process	GO:0043523	16	0.100
response to carbohydrate	GO:0009743	15	0.099
single organism cell adhesion	GO:0098602	47	0.099
regulation of cell migration	GO:0030334	22	0.098
negative regulation of immune system process	GO:0002683	50	0.095
olfactory learning	GO:0008355	56	0.094
positive regulation of cellular component organization	GO:0051130	156	0.094
wound healing	GO:0042060	75	0.092
regulation of immune system process	GO:0002682	176	0.092
proteolysis	GO:0006508	192	0.091
hemocyte differentiation	GO:0042386	38	0.091
positive regulation of cell proliferation	GO:0008284	47	0.090
actin cytoskeleton organization	GO:0030036	206	0.089
spinal cord development	GO:0021510	1	0.089
positive regulation of phosphate metabolic process	GO:0045937	139	0.088
cellular response to hormone stimulus	GO:0032870	44	0.087
epithelial cell differentiation	GO:0030855	322	0.087
heart development	GO:0007507	82	0.086
regulation of cell differentiation	GO:0045595	302	0.086
regulation of neuron projection development	GO:0010975	69	0.085
imaginal disc growth	GO:0007446	37	0.085
negative regulation of catalytic activity	GO:0043086	42	0.084
cellular response to oxidative stress	GO:0034599	28	0.084
single organism biosynthetic process	GO:0044711	206	0.083
regulation of cell cell adhesion	GO:0022407	21	0.082
developmental growth involved in morphogenesis	GO:0060560	65	0.082
organic acid metabolic process	GO:0006082	103	0.081
germ line cyst formation	GO:0048134	44	0.080
cardiovascular system development	GO:0072358	82	0.080
regulation of phosphorus metabolic process	GO:0051174	210	0.079
positive regulation of muscle organ development	GO:0048636	6	0.079
oocyte morphogenesis	GO:0048601	3	0.078
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.077
regulation of protein localization to nucleus	GO:1900180	29	0.077
negative regulation of autophagy	GO:0010507	16	0.077
appendage morphogenesis	GO:0035107	397	0.077
sensory organ morphogenesis	GO:0090596	260	0.075
salivary gland cell autophagic cell death	GO:0035071	83	0.075
small molecule metabolic process	GO:0044281	305	0.075
meiotic nuclear envelope disassembly	GO:0051078	2	0.074
rhythmic behavior	GO:0007622	76	0.073
dendrite regeneration	GO:0031104	2	0.072
dna repair	GO:0006281	54	0.072
renal tubule morphogenesis	GO:0061333	44	0.072
mesenchymal cell differentiation	GO:0048762	1	0.071
regulation of protein import into nucleus	GO:0042306	28	0.070
negative regulation of protein metabolic process	GO:0051248	85	0.070
germ cell migration	GO:0008354	43	0.069
regulation of cell cycle g1 s phase transition	GO:1902806	23	0.068
dendrite development	GO:0016358	204	0.068
ovarian follicle cell stalk formation	GO:0030713	17	0.068
mrna metabolic process	GO:0016071	124	0.067
nitrogen compound transport	GO:0071705	85	0.067
axonal fasciculation	GO:0007413	12	0.066
single organism catabolic process	GO:0044712	228	0.066
proteasomal protein catabolic process	GO:0010498	59	0.066
neuroblast division	GO:0055057	35	0.065
membrane organization	GO:0061024	112	0.065
regulation of cellular ketone metabolic process	GO:0010565	3	0.065
positive regulation of synaptic growth at neuromuscular junction	GO:0045887	26	0.063
response to organonitrogen compound	GO:0010243	75	0.063
embryonic axis specification	GO:0000578	107	0.063
regulation of response to stress	GO:0080134	200	0.062
ribose phosphate metabolic process	GO:0019693	145	0.062
carboxylic acid metabolic process	GO:0019752	92	0.062
regulation of protein catabolic process	GO:0042176	55	0.061
cardiac muscle tissue development	GO:0048738	9	0.059
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090100	9	0.059
positive regulation of locomotion	GO:0040017	8	0.059
endodermal cell differentiation	GO:0035987	3	0.059
regulation of phosphate metabolic process	GO:0019220	210	0.058
proteolysis involved in cellular protein catabolic process	GO:0051603	83	0.057
connective tissue development	GO:0061448	3	0.057
negative regulation of cell adhesion	GO:0007162	9	0.056
intracellular protein transport	GO:0006886	104	0.056
neuronal stem cell division	GO:0036445	35	0.056
modification dependent protein catabolic process	GO:0019941	78	0.056
maternal determination of dorsal ventral axis ovarian follicular epithelium soma encoded	GO:0008071	1	0.055
positive regulation of cell cycle	GO:0045787	43	0.055
regulation of planar cell polarity pathway involved in axis elongation	GO:2000040	2	0.055
regulation of cell proliferation involved in compound eye morphogenesis	GO:2000495	2	0.054
negative regulation of bmp signaling pathway	GO:0030514	12	0.054
female germ line cyst formation	GO:0048135	42	0.054
regulation of dendrite morphogenesis	GO:0048814	28	0.053
negative regulation of cell size	GO:0045792	19	0.053
actin filament based process	GO:0030029	220	0.053
positive regulation of cell growth	GO:0030307	19	0.051
histolysis	GO:0007559	102	0.051
female sex differentiation	GO:0046660	20	0.050
neuron projection regeneration	GO:0031102	8	0.050
regulation of reproductive process	GO:2000241	54	0.050
regulation of hemocyte differentiation	GO:0045610	22	0.050
oocyte microtubule cytoskeleton organization	GO:0016325	35	0.050
eggshell chorion assembly	GO:0007306	66	0.049
negative regulation of signal transduction by p53 class mediator	GO:1901797	1	0.049
cellular response to oxygen levels	GO:0071453	30	0.049
autophagic cell death	GO:0048102	83	0.048
amine metabolic process	GO:0009308	12	0.048
positive regulation of multicellular organism growth	GO:0040018	21	0.048
positive regulation of r7 cell differentiation	GO:0045678	7	0.048
positive regulation of protein transport	GO:0051222	37	0.047
phagocytosis	GO:0006909	215	0.047
positive regulation of purine nucleotide metabolic process	GO:1900544	55	0.047
negative regulation of nucleoside metabolic process	GO:0045978	1	0.047
immune response regulating signaling pathway	GO:0002764	2	0.046
apoptotic process	GO:0006915	159	0.046
regulation of epidermal growth factor receptor signaling pathway	GO:0042058	42	0.045
oocyte fate commitment	GO:0048600	2	0.045
cell substrate adhesion	GO:0031589	10	0.045
glucan biosynthetic process	GO:0009250	2	0.045
stem cell maintenance	GO:0019827	67	0.045
regulation of protein targeting	GO:1903533	29	0.045
developmental cell growth	GO:0048588	52	0.045
positive regulation of protein metabolic process	GO:0051247	128	0.045
regulation of response to nutrient levels	GO:0032107	18	0.045
regulation of synaptic growth at neuromuscular junction	GO:0008582	89	0.045
regulation of nucleocytoplasmic transport	GO:0046822	35	0.044
intracellular signal transduction	GO:0035556	300	0.044
regulation of proteolysis	GO:0030162	87	0.044
neuroblast proliferation	GO:0007405	74	0.044
stem cell development	GO:0048864	79	0.044
regulation of dendrite development	GO:0050773	37	0.044
hormone mediated signaling pathway	GO:0009755	16	0.043
phosphorylation	GO:0016310	294	0.043
maternal determination of dorsal ventral axis ovarian follicular epithelium germ line encoded	GO:0008070	2	0.043
regulation of synapse structure and activity	GO:0050803	128	0.043
apoptotic signaling pathway	GO:0097190	27	0.042
protein targeting	GO:0006605	64	0.041
modification dependent macromolecule catabolic process	GO:0043632	79	0.041

EcR disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.305
vascular disease	DOID:178	0.054
artery disease	DOID:0050828	0.054
cardiovascular system disease	DOID:1287	0.054
aortic disease	DOID:520	0.054
aortic aneurysm	DOID:3627	0.054
female reproductive system disease	DOID:229	0.052
reproductive system disease	DOID:15	0.052
ovarian disease	DOID:1100	0.052
nervous system disease	DOID:863	0.042

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