IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

CG5044 (Dmel_CG5044)

CG5044 gene product from transcript CG5044-RB

(Aliases: Dmel\CG5044,CT16187)

Entrez: 41869
FLYBASE: FBgn0038326
UniProtKB: Q960K8
UniProtKB: Q86BP1

Process Predictions
Disease Predictions

CG5044 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
small molecule metabolic process	GO:0044281	305	0.132
oxoacid metabolic process	GO:0043436	103	0.125
cellular amino acid metabolic process	GO:0006520	61	0.114
cellular catabolic process	GO:0044248	372	0.110
organic acid metabolic process	GO:0006082	103	0.110
carboxylic acid metabolic process	GO:0019752	92	0.084
organonitrogen compound metabolic process	GO:1901564	318	0.080
homeostatic process	GO:0042592	199	0.075
single organism catabolic process	GO:0044712	228	0.068
organic substance catabolic process	GO:1901575	308	0.057
catabolic process	GO:0009056	409	0.057
monocarboxylic acid metabolic process	GO:0032787	29	0.053
carboxylic acid catabolic process	GO:0046395	16	0.048
organic acid catabolic process	GO:0016054	16	0.047
response to other organism	GO:0051707	293	0.045
thioester metabolic process	GO:0035383	3	0.045
oxidation reduction process	GO:0055114	123	0.042
vesicle mediated transport	GO:0016192	381	0.038
body morphogenesis	GO:0010171	2	0.037
response to biotic stimulus	GO:0009607	294	0.036
alpha amino acid metabolic process	GO:1901605	20	0.036
organonitrogen compound catabolic process	GO:1901565	128	0.035
fatty acid metabolic process	GO:0006631	20	0.035
response to oxygen containing compound	GO:1901700	200	0.035
macromolecular complex assembly	GO:0065003	256	0.035
sulfur compound metabolic process	GO:0006790	59	0.032
positive regulation of response to stimulus	GO:0048584	323	0.031
small molecule catabolic process	GO:0044282	21	0.031
imaginal disc derived wing morphogenesis	GO:0007476	337	0.031
endocytosis	GO:0006897	310	0.031
response to organic substance	GO:0010033	284	0.030
protein complex assembly	GO:0006461	200	0.029
growth	GO:0040007	359	0.028
cellular lipid metabolic process	GO:0044255	83	0.027
response to external biotic stimulus	GO:0043207	293	0.027
chemical homeostasis	GO:0048878	92	0.027
organic cyclic compound catabolic process	GO:1901361	168	0.027
response to lipopolysaccharide	GO:0032496	4	0.026
acylglycerol biosynthetic process	GO:0046463	2	0.026
phagocytosis	GO:0006909	215	0.026
cellular ketone metabolic process	GO:0042180	24	0.026
regulation of localization	GO:0032879	275	0.026
ion homeostasis	GO:0050801	55	0.026
appendage morphogenesis	GO:0035107	397	0.026
post embryonic appendage morphogenesis	GO:0035120	385	0.025
multicellular organismal aging	GO:0010259	140	0.025
aging	GO:0007568	143	0.025
kidney development	GO:0001822	3	0.024
regionalization	GO:0003002	416	0.024
phosphorylation	GO:0016310	294	0.024
negative regulation of cellular metabolic process	GO:0031324	382	0.024
small molecule biosynthetic process	GO:0044283	37	0.024
wing disc morphogenesis	GO:0007472	344	0.024
response to abiotic stimulus	GO:0009628	341	0.023
sterol homeostasis	GO:0055092	4	0.023
regulation of cellular ketone metabolic process	GO:0010565	3	0.023
cellular macromolecule localization	GO:0070727	220	0.023
imaginal disc derived appendage development	GO:0048737	399	0.023
appendage development	GO:0048736	401	0.023
very long chain fatty acid metabolic process	GO:0000038	4	0.022
positive regulation of macromolecule metabolic process	GO:0010604	405	0.022
ethanolamine containing compound metabolic process	GO:0042439	4	0.022
positive regulation of cell communication	GO:0010647	250	0.022
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.022
purine ribonucleoside metabolic process	GO:0046128	127	0.022
purine containing compound metabolic process	GO:0072521	155	0.022
nucleotide metabolic process	GO:0009117	161	0.021
organic substance transport	GO:0071702	257	0.021
amine metabolic process	GO:0009308	12	0.021
cellular nitrogen compound catabolic process	GO:0044270	165	0.020
negative regulation of rna biosynthetic process	GO:1902679	240	0.020
organophosphate metabolic process	GO:0019637	195	0.020
immune response activating signal transduction	GO:0002757	2	0.020
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.019
cellular homeostasis	GO:0019725	80	0.019
response to nutrient levels	GO:0031667	114	0.019
immune system process	GO:0002376	347	0.019
connective tissue development	GO:0061448	3	0.019
cellular amine metabolic process	GO:0044106	12	0.019
organelle fission	GO:0048285	340	0.018
kidney epithelium development	GO:0072073	3	0.018
cellular ion homeostasis	GO:0006873	39	0.018
positive regulation of signaling	GO:0023056	243	0.018
positive regulation of signal transduction	GO:0009967	223	0.018
immune response	GO:0006955	246	0.018
lipid modification	GO:0030258	24	0.018
oxidoreduction coenzyme metabolic process	GO:0006733	2	0.018
defense response to other organism	GO:0098542	225	0.018
defense response to bacterium	GO:0042742	178	0.018
regulation of cellular amine metabolic process	GO:0033238	3	0.018
establishment of protein localization	GO:0045184	163	0.018
nucleobase containing small molecule metabolic process	GO:0055086	174	0.018
negative regulation of cellular biosynthetic process	GO:0031327	277	0.018
lipid metabolic process	GO:0006629	121	0.017
ribose phosphate metabolic process	GO:0019693	145	0.017
pyridine containing compound metabolic process	GO:0072524	3	0.017
proteolysis	GO:0006508	192	0.017
establishment of localization in cell	GO:0051649	402	0.017
single organism behavior	GO:0044708	391	0.017
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.017
developmental growth	GO:0048589	280	0.017
tube morphogenesis	GO:0035239	191	0.017
epithelial cell differentiation	GO:0030855	322	0.017
protein modification process	GO:0036211	438	0.017
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.016
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.016
regulation of protein metabolic process	GO:0051246	256	0.016
single organism biosynthetic process	GO:0044711	206	0.016
positive regulation of cellular biosynthetic process	GO:0031328	316	0.016
nucleoside phosphate metabolic process	GO:0006753	162	0.016
nuclear division	GO:0000280	332	0.016
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.016
aromatic compound catabolic process	GO:0019439	166	0.016
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.015
nucleoside metabolic process	GO:0009116	127	0.015
nucleobase containing compound catabolic process	GO:0034655	165	0.015
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.015
single organism cellular localization	GO:1902580	180	0.015
glycosyl compound metabolic process	GO:1901657	127	0.015
purine nucleoside metabolic process	GO:0042278	127	0.015
negative regulation of signal transduction	GO:0009968	206	0.015
regulation of multicellular organismal development	GO:2000026	414	0.015
generation of precursor metabolites and energy	GO:0006091	42	0.015
lipid biosynthetic process	GO:0008610	46	0.015
adult behavior	GO:0030534	137	0.015
intracellular transport	GO:0046907	228	0.015
cellular response to chemical stimulus	GO:0070887	199	0.015
cation homeostasis	GO:0055080	51	0.015
l glutamate import	GO:0051938	1	0.015
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.015
organonitrogen compound biosynthetic process	GO:1901566	117	0.014
response to bacterium	GO:0009617	198	0.014
gland development	GO:0048732	191	0.014
defense response	GO:0006952	300	0.014
positive regulation of gene expression	GO:0010628	290	0.014
camera type eye development	GO:0043010	4	0.014
maintenance of location	GO:0051235	73	0.014
innate immune response	GO:0045087	144	0.014
heterocycle catabolic process	GO:0046700	166	0.014
myotube cell development	GO:0014904	3	0.014
forebrain development	GO:0030900	2	0.014
regulation of molecular function	GO:0065009	217	0.014
positive regulation of multicellular organismal process	GO:0051240	143	0.014
transcription from rna polymerase ii promoter	GO:0006366	368	0.014
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.014
regulation of response to stress	GO:0080134	200	0.013
regulation of catalytic activity	GO:0050790	185	0.013
protein localization	GO:0008104	284	0.013
immune response regulating signaling pathway	GO:0002764	2	0.013
tube development	GO:0035295	244	0.013
regulation of transport	GO:0051049	181	0.013
response to endogenous stimulus	GO:0009719	119	0.013
death	GO:0016265	284	0.013
columnar cuboidal epithelial cell development	GO:0002066	249	0.013
ion transmembrane transport	GO:0034220	122	0.013
nucleoside triphosphate metabolic process	GO:0009141	120	0.013
regulation of immune system process	GO:0002682	176	0.013
protein transport	GO:0015031	155	0.013
cellular protein modification process	GO:0006464	438	0.013
organelle assembly	GO:0070925	198	0.013
cellular protein localization	GO:0034613	160	0.012
response to organonitrogen compound	GO:0010243	75	0.012
digestive tract development	GO:0048565	149	0.012
eye development	GO:0001654	323	0.012
purine ribonucleotide metabolic process	GO:0009150	145	0.012
cell proliferation	GO:0008283	299	0.012
positive regulation of protein metabolic process	GO:0051247	128	0.012
response to organophosphorus	GO:0046683	2	0.012
regulation of intracellular signal transduction	GO:1902531	236	0.012
ion transport	GO:0006811	145	0.012
eye morphogenesis	GO:0048592	260	0.012
positive regulation of developmental process	GO:0051094	143	0.012
programmed cell death	GO:0012501	257	0.012
purine ribonucleoside catabolic process	GO:0046130	112	0.012
ribonucleotide metabolic process	GO:0009259	145	0.012
negative regulation of biosynthetic process	GO:0009890	277	0.012
negative regulation of gene expression	GO:0010629	387	0.012
response to hexose	GO:0009746	3	0.012
cytoplasmic transport	GO:0016482	130	0.012
embryo development ending in birth or egg hatching	GO:0009792	152	0.012
telencephalon development	GO:0021537	2	0.012
negative regulation of rna metabolic process	GO:0051253	251	0.012
regulation of immune response	GO:0050776	118	0.012
pattern recognition receptor signaling pathway	GO:0002221	2	0.012
posttranscriptional regulation of gene expression	GO:0010608	145	0.011
positive regulation of cell motility	GO:2000147	3	0.011
positive regulation of cell migration	GO:0030335	2	0.011
purine nucleoside catabolic process	GO:0006152	112	0.011
regulation of establishment of protein localization	GO:0070201	61	0.011
cellular response to molecule of bacterial origin	GO:0071219	3	0.011
negative regulation of signaling	GO:0023057	219	0.011
notch signaling pathway	GO:0007219	120	0.011
cellular lipid catabolic process	GO:0044242	16	0.011
response to monosaccharide	GO:0034284	4	0.011
nephron epithelium development	GO:0072009	3	0.011
regulation of developmental growth	GO:0048638	174	0.011
taxis	GO:0042330	304	0.011
carbohydrate derivative metabolic process	GO:1901135	217	0.011
positive regulation of molecular function	GO:0044093	136	0.011
anion homeostasis	GO:0055081	3	0.011
positive regulation of lipid metabolic process	GO:0045834	4	0.011
positive regulation of immune system process	GO:0002684	68	0.011
response to nitrogen compound	GO:1901698	90	0.011
mitotic nuclear division	GO:0007067	213	0.011
atp metabolic process	GO:0046034	49	0.011
localization of cell	GO:0051674	257	0.011
compound eye morphogenesis	GO:0001745	249	0.011
response to copper ion	GO:0046688	4	0.011
regulation of phosphorus metabolic process	GO:0051174	210	0.011
spindle organization	GO:0007051	253	0.011
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.011
regulation of notch signaling pathway	GO:0008593	100	0.011
mitotic spindle organization	GO:0007052	220	0.011
acyl coa metabolic process	GO:0006637	3	0.011
protein complex biogenesis	GO:0070271	201	0.011
transition metal ion homeostasis	GO:0055076	17	0.011
ribonucleoside metabolic process	GO:0009119	127	0.010
compound eye development	GO:0048749	307	0.010
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.010
positive regulation of catalytic activity	GO:0043085	118	0.010
ribonucleoside catabolic process	GO:0042454	112	0.010
purine nucleotide metabolic process	GO:0006163	146	0.010
embryonic morphogenesis	GO:0048598	206	0.010
positive regulation of biosynthetic process	GO:0009891	316	0.010
triglyceride biosynthetic process	GO:0019432	2	0.010
response to alcohol	GO:0097305	95	0.010
membrane organization	GO:0061024	112	0.010
positive regulation of intracellular signal transduction	GO:1902533	116	0.010
neurological system process	GO:0050877	358	0.010
negative regulation of response to stimulus	GO:0048585	258	0.010
digestive tract morphogenesis	GO:0048546	127	0.010
determination of adult lifespan	GO:0008340	137	0.010
intracellular signal transduction	GO:0035556	300	0.010
regulation of multi organism process	GO:0043900	131	0.010
nicotinamide nucleotide metabolic process	GO:0046496	2	0.010
nucleoside triphosphate catabolic process	GO:0009143	108	0.010
regulation of cellular protein metabolic process	GO:0032268	243	0.010
transmembrane transport	GO:0055085	139	0.010
lateral inhibition	GO:0046331	206	0.010

CG5044 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of metabolism	DOID:0014667	0.048
inherited metabolic disorder	DOID:655	0.048
disease of anatomical entity	DOID:7	0.028
integumentary system disease	DOID:16	0.013
eye disease	DOID:5614	0.012
eye and adnexa disease	DOID:1492	0.012
sensory system disease	DOID:0050155	0.012
nervous system disease	DOID:863	0.012
cardiovascular system disease	DOID:1287	0.010
diabetes mellitus	DOID:9351	0.010
acquired metabolic disease	DOID:0060158	0.010
carbohydrate metabolism disease	DOID:0050013	0.010
glucose metabolism disease	DOID:4194	0.010

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