Drosophila melanogaster

11 known processes

whd (Dmel_CG12891)

withered

(Aliases: BEST:GH27794,CG12891,gh27794,CPTI,Dmel\CG12891)

whd biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
ameboidal type cell migrationGO:00016671510.404
response to other organismGO:00517072930.379
triglyceride catabolic processGO:001943330.351
response to external biotic stimulusGO:00432072930.297
defense response to virusGO:0051607230.273
defense responseGO:00069523000.257
response to virusGO:0009615280.233
immune system processGO:00023763470.232
tissue migrationGO:00901301550.221
single organism catabolic processGO:00447122280.204
response to biotic stimulusGO:00096072940.192
epithelial cell migrationGO:00106311480.178
columnar cuboidal epithelial cell developmentGO:00020662490.175
response to lipopolysaccharideGO:003249640.167
columnar cuboidal epithelial cell differentiationGO:00020652560.151
lipopolysaccharide mediated signaling pathwayGO:003166310.151
ovarian follicle cell migrationGO:00072971210.150
response to bacteriumGO:00096171980.149
regulation of response to biotic stimulusGO:0002831630.148
catabolic processGO:00090564090.135
regulation of biosynthetic process of antibacterial peptides active against gram positive bacteriaGO:000281630.135
response to monosaccharideGO:003428440.123
regulation of catabolic processGO:00098941700.116
defense response to bacteriumGO:00427421780.115
homeostatic processGO:00425921990.113
organic substance catabolic processGO:19015753080.111
defense response to other organismGO:00985422250.107
immune responseGO:00069552460.106
response to glucoseGO:000974920.101
vesicle mediated transportGO:00161923810.100
cell migrationGO:00164772380.099
defense response to fungusGO:0050832480.097
cellular response to arsenic containing substanceGO:007124360.096
g protein coupled receptor signaling pathwayGO:00071861360.096
localization of cellGO:00516742570.094
phospholipid homeostasisGO:005509110.093
negative regulation of response to stimulusGO:00485852580.089
negative regulation of cell communicationGO:00106482230.085
cell motilityGO:00488702510.084
regulation of response to stressGO:00801342000.079
epithelium migrationGO:00901321480.077
positive regulation of defense responseGO:0031349590.076
positive regulation of lipid metabolic processGO:004583440.076
connective tissue developmentGO:006144830.075
response to hexoseGO:000974630.075
cellular response to lipopolysaccharideGO:007122230.071
acyl coa metabolic processGO:000663730.071
wing disc morphogenesisGO:00074723440.070
cellular response to dna damage stimulusGO:00069742230.069
mucosal immune responseGO:0002385100.068
organonitrogen compound metabolic processGO:19015643180.068
lipid metabolic processGO:00066291210.067
endocytosisGO:00068973100.066
cellular catabolic processGO:00442483720.065
small molecule metabolic processGO:00442813050.064
response to molecule of bacterial originGO:000223770.064
response to radiationGO:00093141550.064
acylglycerol catabolic processGO:004646430.063
response to organic substanceGO:00100332840.062
epithelial cell developmentGO:00020642740.062
agingGO:00075681430.061
regulation of defense responseGO:00313471020.061
single organism behaviorGO:00447083910.060
innate immune responseGO:00450871440.060
positive regulation of response to stimulusGO:00485843230.057
border follicle cell migrationGO:00072981130.056
response to ionizing radiationGO:0010212320.056
response to peptidoglycanGO:003249420.056
secretionGO:00469031090.056
negative regulation of signal transductionGO:00099682060.054
response to abiotic stimulusGO:00096283410.053
phagocytosisGO:00069092150.053
post embryonic appendage morphogenesisGO:00351203850.052
epithelial cell differentiationGO:00308553220.052
branched chain amino acid transportGO:001580330.051
regulation of defense response to virusGO:0050688140.051
imaginal disc derived wing morphogenesisGO:00074763370.051
telencephalon developmentGO:002153720.051
cellular response to chemical stimulusGO:00708871990.051
positive regulation of cell migrationGO:003033520.050
negative regulation of cellular metabolic processGO:00313243820.049
deathGO:00162652840.049
positive regulation of nitrogen compound metabolic processGO:00511733540.049
neutral lipid biosynthetic processGO:004646020.048
jak stat cascadeGO:0007259490.047
positive regulation of nucleic acid templated transcriptionGO:19035082660.047
imaginal disc derived appendage morphogenesisGO:00351143950.046
neurological system processGO:00508773580.045
macromolecule catabolic processGO:00090571610.044
immune effector processGO:0002252980.044
carbohydrate derivative catabolic processGO:19011361180.043
nucleobase containing small molecule metabolic processGO:00550861740.043
response to oxidative stressGO:0006979860.042
response to endogenous stimulusGO:00097191190.042
organic substance transportGO:00717022570.042
glucosamine containing compound catabolic processGO:190107230.041
chemotaxisGO:00069352490.041
cellular response to peptide hormone stimulusGO:0071375280.041
establishment of localization in cellGO:00516494020.041
cellular lipid metabolic processGO:0044255830.040
positive regulation of signalingGO:00230562430.040
cell deathGO:00082192790.040
purine nucleotide metabolic processGO:00061631460.040
locomotory behaviorGO:00076261760.040
regulation of localizationGO:00328792750.040
positive regulation of macromolecule biosynthetic processGO:00105572830.039
carbohydrate derivative metabolic processGO:19011352170.039
appendage morphogenesisGO:00351073970.039
positive regulation of signal transductionGO:00099672230.038
tissue morphogenesisGO:00487292970.038
cellular response to mechanical stimulusGO:007126020.037
regulation of response to external stimulusGO:00321011150.037
positive regulation of gene expressionGO:00106282900.037
acylglycerol biosynthetic processGO:004646320.037
regulation of immune system processGO:00026821760.037
lateral inhibitionGO:00463312060.036
neutral lipid catabolic processGO:004646130.036
positive regulation of cellular biosynthetic processGO:00313283160.036
regulation of immune responseGO:00507761180.036
cellular response to abiotic stimulusGO:0071214580.036
pattern recognition receptor signaling pathwayGO:000222120.036
chemosensory behaviorGO:00076351060.035
cellular response to endogenous stimulusGO:0071495800.035
response to nitrogen compoundGO:1901698900.035
cuticle developmentGO:0042335860.035
appendage developmentGO:00487364010.035
digestive system developmentGO:00551231490.034
innate immune response activating signal transductionGO:000275820.034
purine nucleotide catabolic processGO:00061951090.034
chromosome segregationGO:00070591570.034
positive regulation of rna biosynthetic processGO:19026802660.034
negative regulation of signalingGO:00230572190.033
maintenance of locationGO:0051235730.033
enzyme linked receptor protein signaling pathwayGO:00071671790.032
cellular response to radiationGO:0071478520.032
growthGO:00400073590.032
anatomical structure homeostasisGO:0060249970.032
cell growthGO:00160491080.032
defense response to gram negative bacteriumGO:0050829940.032
long term memoryGO:0007616620.031
tissue homeostasisGO:0001894360.031
response to paraquatGO:190156240.031
positive regulation of transcription dna templatedGO:00458932660.031
positive regulation of defense response to bacteriumGO:1900426230.030
cellular response to organic substanceGO:00713101320.030
multicellular organismal agingGO:00102591400.030
positive regulation of innate immune responseGO:0045089380.030
positive regulation of biosynthetic processGO:00098913160.030
anion homeostasisGO:005508130.030
cellular response to biotic stimulusGO:007121640.030
imaginal disc derived appendage developmentGO:00487373990.030
forebrain developmentGO:003090020.030
transcription from rna polymerase ii promoterGO:00063663680.030
digestive tract morphogenesisGO:00485461270.029
organ or tissue specific immune responseGO:0002251100.029
cardiocyte differentiationGO:0035051290.029
triglyceride biosynthetic processGO:001943220.029
lipid localizationGO:0010876540.029
ovarian follicle cell developmentGO:00307072480.029
multicellular organismal homeostasisGO:0048871410.029
digestive tract developmentGO:00485651490.029
cellular response to oxygen containing compoundGO:1901701790.029
developmental maturationGO:00217001720.029
thioester metabolic processGO:003538330.028
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.028
regionalizationGO:00030024160.028
regulation of developmental growthGO:00486381740.028
chemical homeostasisGO:0048878920.028
organic acid metabolic processGO:00060821030.028
phosphorylationGO:00163102940.027
intracellular signal transductionGO:00355563000.027
cellular response to ionizing radiationGO:0071479150.027
activation of innate immune responseGO:000221840.027
regulation of innate immune responseGO:0045088710.027
antimicrobial humoral responseGO:0019730990.027
multi multicellular organism processGO:00447061230.026
negative regulation of cellular biosynthetic processGO:00313272770.026
regulation of cell cycleGO:00517262910.026
regulation of stress activated mapk cascadeGO:0032872410.026
ribose phosphate metabolic processGO:00196931450.026
cell maturationGO:00484691440.026
positive regulation of cell communicationGO:00106472500.026
response to starvationGO:0042594970.026
lipid homeostasisGO:0055088330.026
secretion by cellGO:00329401010.026
regulation of response to oxidative stressGO:190288240.025
protein modification processGO:00362114380.025
response to organonitrogen compoundGO:0010243750.025
glycerolipid catabolic processGO:004650330.025
taxisGO:00423303040.025
regulation of circadian rhythmGO:0042752490.025
heart developmentGO:0007507820.025
positive regulation of nervous system developmentGO:0051962690.025
regulation of cellular catabolic processGO:00313291570.025
negative regulation of macromolecule biosynthetic processGO:00105582700.025
mitochondrion organizationGO:0007005650.024
axon guidanceGO:00074112330.024
regulation of cellular response to stressGO:0080135890.024
regulation of intracellular signal transductionGO:19025312360.024
regulation of anatomical structure sizeGO:00900661630.024
dorsal ventral pattern formationGO:00099531330.024
positive regulation of cell differentiationGO:0045597640.023
defense response to gram positive bacteriumGO:0050830410.023
positive regulation of cell motilityGO:200014730.023
cellular response to molecule of bacterial originGO:007121930.023
peptidyl lysine acetylationGO:0018394390.023
response to oxygen containing compoundGO:19017002000.022
axonogenesisGO:00074092900.022
adult locomotory behaviorGO:0008344760.022
antimicrobial peptide productionGO:0002775460.022
determination of adult lifespanGO:00083401370.022
regulation of multi organism processGO:00439001310.022
morphogenesis of an epitheliumGO:00020092760.022
regulation of autophagyGO:0010506620.022
positive regulation of intracellular signal transductionGO:19025331160.022
positive regulation of production of molecular mediator of immune responseGO:0002702280.021
hindgut developmentGO:0061525580.021
purine nucleoside metabolic processGO:00422781270.021
gtp catabolic processGO:0006184720.021
response to organophosphorusGO:004668320.021
regulation of cell deathGO:00109411730.021
carboxylic acid metabolic processGO:0019752920.021
developmental growthGO:00485892800.021
positive regulation of immune responseGO:0050778630.021
spindle organizationGO:00070512530.020
protein localizationGO:00081042840.020
aromatic compound catabolic processGO:00194391660.020
nitrogen compound transportGO:0071705850.020
antibacterial humoral responseGO:0019731440.020
glycerolipid metabolic processGO:0046486340.020
negative regulation of mitotic cell cycleGO:00459301090.020
response to growth factorGO:0070848310.020
actin filament based processGO:00300292200.020
lipid storageGO:0019915380.020
stress activated mapk cascadeGO:0051403520.020
purine containing compound metabolic processGO:00725211550.020
cellular ketone metabolic processGO:0042180240.020
immune response regulating signaling pathwayGO:000276420.020
synaptic target recognitionGO:0008039450.019
response to light stimulusGO:00094161240.019
alpha amino acid metabolic processGO:1901605200.019
spinal cord developmentGO:002151010.019
nuclear importGO:0051170510.019
lipid catabolic processGO:0016042210.019
ribonucleoside metabolic processGO:00091191270.019
regulation of phosphorus metabolic processGO:00511742100.019
oxoacid metabolic processGO:00434361030.019
peptide metabolic processGO:0006518800.019
negative regulation of nucleic acid templated transcriptionGO:19035072400.019
positive regulation of catabolic processGO:00098961050.019
ribonucleotide catabolic processGO:00092611090.019
cellular response to nutrient levelsGO:0031669620.019
learningGO:0007612750.018
neurotransmitter metabolic processGO:004213320.018
spermatogenesisGO:00072832000.018
single organism carbohydrate metabolic processGO:0044723720.018
cell proliferationGO:00082832990.018
wound healingGO:0042060750.018
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.018
negative regulation of protein metabolic processGO:0051248850.018
glial cell differentiationGO:0010001350.018
peptidyl amino acid modificationGO:00181931050.018
regulation of cellular ketone metabolic processGO:001056530.018
cognitionGO:00508901410.018
regulation of jnk cascadeGO:0046328400.018
cell recognitionGO:00080371020.018
negative regulation of immune system processGO:0002683500.018
regulation of cellular component sizeGO:0032535980.018
carbohydrate biosynthetic processGO:0016051170.017
positive regulation of immune system processGO:0002684680.017
negative regulation of cell cycle phase transitionGO:19019881030.017
positive regulation of macromolecule metabolic processGO:00106044050.017
cellular amino acid metabolic processGO:0006520610.017
cellular response to metal ionGO:007124860.017
cellular protein modification processGO:00064644380.017
associative learningGO:0008306650.017
negative regulation of apoptotic processGO:0043066630.017
cellular response to lipidGO:0071396200.017
hindbrain developmentGO:003090220.017
cellular response to starvationGO:0009267610.017
negative regulation of defense responseGO:0031348350.017
amine metabolic processGO:0009308120.017
glial cell developmentGO:0021782270.017
salivary gland developmentGO:00074311620.017
cellular response to external stimulusGO:0071496660.017
positive regulation of immune effector processGO:0002699280.017
positive regulation of response to biotic stimulusGO:0002833310.017
protein transportGO:00150311550.017
response to peptide hormoneGO:0043434290.016
apoptotic processGO:00069151590.016
response to nutrient levelsGO:00316671140.016
negative regulation of nitrogen compound metabolic processGO:00511722650.016
regulation of sequestering of triglycerideGO:001088930.016
gliogenesisGO:0042063800.016
regulation of antimicrobial peptide productionGO:0002784440.016
carbohydrate homeostasisGO:0033500120.016
response to lipidGO:0033993380.016
tube developmentGO:00352952440.016
regulation of immune effector processGO:0002697520.016
regulation of humoral immune responseGO:0002920510.016
peptide biosynthetic processGO:0043043420.016
jnk cascadeGO:0007254500.016
establishment of protein localizationGO:00451841630.016
positive regulation of cell sizeGO:0045793210.016
organic cyclic compound catabolic processGO:19013611680.016
ion homeostasisGO:0050801550.016
positive regulation of multicellular organismal processGO:00512401430.015
regulation of mitotic cell cycleGO:00073461900.015
regulation of cellular response to oxidative stressGO:190040740.015
organophosphate metabolic processGO:00196371950.015
regulation of growthGO:00400082330.015
learning or memoryGO:00076111410.015
negative regulation of gene expressionGO:00106293870.015
mapk cascadeGO:00001651070.015
central nervous system developmentGO:00074172010.015
response to organic cyclic compoundGO:0014070890.015
regulation of multicellular organismal developmentGO:20000264140.015
positive regulation of protein metabolic processGO:00512471280.015
respiratory system developmentGO:00605412130.015
regulation of phosphate metabolic processGO:00192202100.015
nucleoside triphosphate catabolic processGO:00091431080.015
metal ion homeostasisGO:0055065440.015
nucleotide catabolic processGO:00091661090.015
stress activated protein kinase signaling cascadeGO:0031098550.015
negative regulation of intracellular signal transductionGO:1902532570.015
gtp metabolic processGO:0046039720.015
glycosyl compound metabolic processGO:19016571270.014
developmental programmed cell deathGO:00106231380.014
purine ribonucleotide metabolic processGO:00091501450.014
signal transduction in response to dna damageGO:004277030.014
positive regulation of antimicrobial humoral responseGO:0002760280.014
negative regulation of developmental processGO:00510932010.014
nucleobase containing compound catabolic processGO:00346551650.014
regulation of cell morphogenesisGO:00226041630.014
positive regulation of antimicrobial peptide biosynthetic processGO:0002807260.014
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.014
regulation of locomotionGO:0040012420.014
peptidoglycan recognition protein signaling pathwayGO:0061057160.014
regulation of stress activated protein kinase signaling cascadeGO:0070302420.014
regulation of apoptotic processGO:00429811300.014
phototaxisGO:0042331210.014
dendrite morphogenesisGO:00488131990.014
negative regulation of rna metabolic processGO:00512532510.014
positive regulation of growthGO:0045927750.014
cellular component assembly involved in morphogenesisGO:00109271510.014
ribonucleotide metabolic processGO:00092591450.014
acylglycerol metabolic processGO:0006639120.014
g2 dna damage checkpointGO:0031572690.014
negative regulation of rna biosynthetic processGO:19026792400.014
negative regulation of cell deathGO:0060548810.014
regulation of lipid metabolic processGO:0019216150.013
aminoglycan metabolic processGO:0006022180.013
somatic muscle developmentGO:0007525660.013
regulation of mapk cascadeGO:0043408920.013
leucine transportGO:001582030.013
response to woundingGO:0009611940.013
cellular response to cadmium ionGO:007127660.013
protein acylationGO:0043543420.013
terminal button organizationGO:0072553190.013
response to temperature stimulusGO:00092661060.013
salivary gland cell autophagic cell deathGO:0035071830.013
regulation of cellular amine metabolic processGO:003323830.013
cellular nitrogen compound catabolic processGO:00442701650.013
positive regulation of rna metabolic processGO:00512542710.013
phagolysosome assemblyGO:000184520.013
lipid modificationGO:0030258240.013
positive regulation of developmental processGO:00510941430.013
regulation of protein metabolic processGO:00512462560.013
l amino acid importGO:004309220.013
purine containing compound catabolic processGO:00725231120.013
positive regulation of reactive oxygen species metabolic processGO:200037900.013
carbohydrate metabolic processGO:0005975820.013
cation homeostasisGO:0055080510.013
nuclear divisionGO:00002803320.013
tissue deathGO:00162711020.013
negative regulation of biosynthetic processGO:00098902770.013
embryonic morphogenesisGO:00485982060.013
cellular response to extracellular stimulusGO:0031668640.013
adult chitin containing cuticle pigmentationGO:0048085160.013
oxidation reduction processGO:00551141230.012
organelle assemblyGO:00709251980.012
cellular response to organonitrogen compoundGO:0071417360.012
acetylcholine catabolic processGO:000658110.012
regulation of cell growthGO:0001558430.012
response to heatGO:0009408630.012
cell adhesionGO:00071551360.012
regulation of transcription from rna polymerase ii promoterGO:00063573780.012
regulation of cell proliferationGO:00421271630.012
amine catabolic processGO:000931010.012
regulation of lipid storageGO:0010883220.012
triglyceride metabolic processGO:0006641120.012
epiboly involved in wound healingGO:009050520.012
ribonucleoside triphosphate metabolic processGO:00091991190.012
negative regulation of sequence specific dna binding transcription factor activityGO:004343340.012
molting cycle processGO:0022404290.012
sex differentiationGO:0007548810.012
nucleoside triphosphate metabolic processGO:00091411200.012
regulation of nervous system developmentGO:00519602480.012
cholesterol homeostasisGO:004263230.012
endomembrane system organizationGO:00102561190.012
programmed cell deathGO:00125012570.012
cell adhesion involved in heart morphogenesisGO:0061343120.012
positive regulation of cellular catabolic processGO:0031331950.012
positive regulation of lipid storageGO:001088440.012
olfactory behaviorGO:0042048970.012
regulation of gene expression epigeneticGO:00400291280.012
protein targeting to nucleusGO:0044744510.012
negative regulation of nervous system developmentGO:0051961920.011
regulation of anatomical structure morphogenesisGO:00226032420.011
triglyceride homeostasisGO:0070328180.011
production of molecular mediator of immune responseGO:0002440460.011
internal protein amino acid acetylationGO:0006475380.011
cuticle pigmentationGO:0048067220.011
histolysisGO:00075591020.011
response to extracellular stimulusGO:00099911160.011
regulation of dna templated transcription in response to stressGO:004362040.011
negative regulation of transcription dna templatedGO:00458922370.011
response to hypoxiaGO:0001666530.011
response to fungusGO:0009620500.011
purine ribonucleoside triphosphate metabolic processGO:00092051190.011
positive regulation of phosphorus metabolic processGO:00105621390.011
intracellular transportGO:00469072280.011
cellular response to ethanolGO:007136140.011
regulation of adult chitin containing cuticle pigmentationGO:0048082130.011
regulation of programmed cell deathGO:00430671520.011
positive regulation of biosynthetic process of antibacterial peptides active against gram positive bacteriaGO:000696530.011
septate junction assemblyGO:0019991260.011
signal transduction by phosphorylationGO:00230141070.011
biosynthetic process of antibacterial peptides active against gram negative bacteriaGO:0002812140.011
embryonic development via the syncytial blastodermGO:00017001480.011
positive regulation of cellular component biogenesisGO:0044089800.011
response to salt stressGO:0009651110.011
regulation of transportGO:00510491810.011
response to copper ionGO:004668840.011
dna integrity checkpointGO:0031570810.011
regulation of secretionGO:0051046440.010
muscle structure developmentGO:00610612240.010
negative regulation of cellular protein metabolic processGO:0032269850.010
sensory perceptionGO:00076001960.010
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.010
cellular amine metabolic processGO:0044106120.010
purine ribonucleoside catabolic processGO:00461301120.010
amino sugar catabolic processGO:004634830.010
positive regulation of catalytic activityGO:00430851180.010
neutral lipid metabolic processGO:0006638120.010
regulation of steroid metabolic processGO:001921820.010
acetylcholine metabolic processGO:000829120.010
response to oxygen radicalGO:000030530.010

whd disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.047
acquired metabolic diseaseDOID:006015800.047
disease of anatomical entityDOID:700.023
glucose metabolism diseaseDOID:419400.020
carbohydrate metabolism diseaseDOID:005001300.020
familial visceral amyloidosisDOID:005063600.015
amyloidosisDOID:912000.015
diabetes mellitusDOID:935100.014
type 2 diabetes mellitusDOID:935200.014
nervous system diseaseDOID:86300.013
disease of cellular proliferationDOID:1456600.011
cancerDOID:16200.011