Drosophila melanogaster

123 known processes

Hrb98DE (Dmel_CG9983)

Heterogeneous nuclear ribonucleoprotein at 98DE

(Aliases: E7Delta6,Hrb1,hrp38,HRB98DE/hrp38,HDP(P9),p9,Pen9,anon-E7Delta6,Dmel\CG9983,hrb98DE,CG9983)

Hrb98DE biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of transcription dna templatedGO:00458922370.687
Mouse
negative regulation of biosynthetic processGO:00098902770.636
Mouse
negative regulation of gene expressionGO:00106293870.591
negative regulation of rna biosynthetic processGO:19026792400.571
Mouse
apoptotic processGO:00069151590.498
chromosome organizationGO:00512763600.491
regulation of programmed cell deathGO:00430671520.485
response to external biotic stimulusGO:00432072930.467
meiotic cell cycle processGO:19030461320.450
regulation of transcription from rna polymerase ii promoterGO:00063573780.445
Mouse
mrna metabolic processGO:00160711240.440
translationGO:0006412690.434
multicellular organismal agingGO:00102591400.434
Worm
negative regulation of cellular biosynthetic processGO:00313272770.415
Mouse
immune system processGO:00023763470.410
muscle structure developmentGO:00610612240.378
deathGO:00162652840.357
negative regulation of nitrogen compound metabolic processGO:00511722650.338
regulation of cell deathGO:00109411730.334
response to other organismGO:00517072930.332
cellular macromolecule localizationGO:00707272200.330
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.285
Mouse
transcription from rna polymerase ii promoterGO:00063663680.277
Mouse
regulation of apoptotic processGO:00429811300.269
negative regulation of nucleic acid templated transcriptionGO:19035072400.253
Mouse
regulation of rna splicingGO:0043484690.243
rna processingGO:00063961470.238
lateral inhibitionGO:00463312060.229
protein localizationGO:00081042840.227
nuclear divisionGO:00002803320.223
Fly
negative regulation of nucleobase containing compound metabolic processGO:00459342610.222
stem cell maintenanceGO:0019827670.222
stem cell developmentGO:0048864790.221
negative regulation of cellular metabolic processGO:00313243820.219
mrna processingGO:00063971040.218
positive regulation of cellular component organizationGO:00511301560.214
determination of adult lifespanGO:00083401370.213
Worm
positive regulation of cell deathGO:0010942690.197
asymmetric stem cell divisionGO:0098722490.196
nucleosome organizationGO:0034728590.196
cell deathGO:00082192790.194
mrna catabolic processGO:0006402330.187
posttranscriptional regulation of gene expressionGO:00106081450.181
positive regulation of macromolecule metabolic processGO:00106044050.175
macromolecular complex assemblyGO:00650032560.165
negative regulation of rna metabolic processGO:00512532510.159
imaginal disc derived appendage developmentGO:00487373990.158
mitotic spindle organizationGO:00070522200.150
posttranscriptional gene silencingGO:0016441460.150
cellular nitrogen compound catabolic processGO:00442701650.148
spindle organizationGO:00070512530.148
regulation of mitotic cell cycleGO:00073461900.148
regulation of mrna metabolic processGO:1903311720.147
positive regulation of programmed cell deathGO:0043068620.146
muscle organ developmentGO:00075171270.145
dendrite developmentGO:00163582040.143
growthGO:00400073590.142
Worm
negative regulation of macromolecule biosynthetic processGO:00105582700.141
Mouse
response to biotic stimulusGO:00096072940.140
regulation of meiosisGO:004002030.140
intercellular bridge organizationGO:0043063140.132
nucleobase containing compound catabolic processGO:00346551650.130
regionalizationGO:00030024160.118
response to abiotic stimulusGO:00096283410.109
Fly
regulation of developmental growthGO:00486381740.109
response to bacteriumGO:00096171980.107
organelle fissionGO:00482853400.107
Fly
modification dependent macromolecule catabolic processGO:0043632790.107
rna catabolic processGO:0006401370.104
cellular macromolecular complex assemblyGO:00346221530.102
regulation of mrna splicing via spliceosomeGO:0048024640.101
oocyte differentiationGO:00099941450.101
agingGO:00075681430.101
Worm
negative regulation of translationGO:0017148280.101
spindle elongationGO:0051231830.100
stem cell differentiationGO:00488631170.099
negative regulation of cell cycle processGO:00109481090.098
programmed cell deathGO:00125012570.098
cell fate determinationGO:0001709910.098
organonitrogen compound metabolic processGO:19015643180.097
regulation of growthGO:00400082330.097
morphogenesis of a polarized epitheliumGO:0001738930.094
regulation of organelle organizationGO:00330431960.093
negative regulation of developmental processGO:00510932010.090
regulation of translationGO:0006417560.090
cell cell signaling involved in cell fate commitmentGO:00451682100.088
imaginal disc derived appendage morphogenesisGO:00351143950.087
positive regulation of transcription dna templatedGO:00458932660.085
aromatic compound catabolic processGO:00194391660.084
mitotic spindle elongationGO:0000022810.081
negative regulation of gene expression epigeneticGO:0045814770.081
cellular protein modification processGO:00064644380.080
regulation of gene expression epigeneticGO:00400291280.080
negative regulation of cell deathGO:0060548810.078
response to dsrnaGO:0043331150.078
meiotic nuclear divisionGO:00071261510.076
defense response to other organismGO:00985422250.076
body morphogenesisGO:001017120.076
regulation of cellular protein metabolic processGO:00322682430.076
single organism cellular localizationGO:19025801800.074
positive regulation of apoptotic processGO:0043065470.073
histone exchangeGO:0043486210.073
developmental growthGO:00485892800.073
antimicrobial peptide productionGO:0002775460.072
meiotic cell cycleGO:00513211710.072
negative regulation of cell cycle phase transitionGO:19019881030.071
dna metabolic processGO:00062592270.070
protein dna complex subunit organizationGO:0071824860.069
regulation of localizationGO:00328792750.068
gene silencing by rnaGO:0031047570.067
microtubule organizing center organizationGO:00310231680.065
gene silencingGO:00164581380.064
chromatin organizationGO:00063252070.063
morphogenesis of embryonic epitheliumGO:0016331940.061
embryo development ending in birth or egg hatchingGO:00097921520.061
Worm
alternative mrna splicing via spliceosomeGO:0000380600.060
embryonic morphogenesisGO:00485982060.060
cellular protein localizationGO:00346131600.059
endocytosisGO:00068973100.059
negative regulation of cell communicationGO:00106482230.058
central nervous system developmentGO:00074172010.058
positive regulation of multi organism processGO:0043902400.057
positive regulation of signal transductionGO:00099672230.057
cell divisionGO:00513012480.056
dendrite morphogenesisGO:00488131990.056
axon guidanceGO:00074112330.054
synapse organizationGO:00508081960.053
organic substance transportGO:00717022570.053
Human
positive regulation of signalingGO:00230562430.052
dorsal ventral pattern formationGO:00099531330.052
regulation of multi organism processGO:00439001310.052
regulation of response to stressGO:00801342000.052
male gamete generationGO:00482322010.052
Fly
positive regulation of transportGO:0051050920.052
regulation of cell cycleGO:00517262910.051
rna splicingGO:0008380830.051
small molecule metabolic processGO:00442813050.051
positive regulation of rna biosynthetic processGO:19026802660.050
protein transportGO:00150311550.049
sensory organ morphogenesisGO:00905962600.049
chromosome localizationGO:0050000200.049
regulation of immune responseGO:00507761180.048
regulation of immune system processGO:00026821760.048
regulation of canonical wnt signaling pathwayGO:0060828150.047
negative regulation of cellular component organizationGO:00511291080.047
peptide metabolic processGO:0006518800.047
positive regulation of nucleic acid templated transcriptionGO:19035082660.046
organic substance catabolic processGO:19015753080.046
regulation of mrna processingGO:0050684710.046
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377730.046
nucleus organizationGO:0006997450.046
establishment of planar polarityGO:0001736870.045
chromatin remodelingGO:0006338720.045
nuclear body organizationGO:003057560.045
apoptotic signaling pathwayGO:0097190270.045
homeostatic processGO:00425921990.045
cellular macromolecule catabolic processGO:00442651360.045
regulation of cell differentiationGO:00455953020.044
purine nucleotide catabolic processGO:00061951090.044
vesicle mediated transportGO:00161923810.043
eye developmentGO:00016543230.043
positive regulation of response to stimulusGO:00485843230.042
response to starvationGO:0042594970.042
Fly
positive regulation of nitrogen compound metabolic processGO:00511733540.041
regulation of anatomical structure morphogenesisGO:00226032420.041
dna damage checkpointGO:0000077780.040
immune responseGO:00069552460.039
single organism behaviorGO:00447083910.039
amide biosynthetic processGO:0043604420.039
mitotic nuclear divisionGO:00070672130.039
Fly
imaginal disc derived leg morphogenesisGO:0007480800.038
nuclear transcribed mrna catabolic processGO:0000956240.038
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.037
Mouse
gene silencing by mirnaGO:0035195220.037
oocyte developmentGO:00485991240.037
maintenance of protein location in cellGO:0032507260.037
chromosome segregationGO:00070591570.036
synapse assemblyGO:00074161430.035
secretionGO:00469031090.035
organic cyclic compound catabolic processGO:19013611680.035
meiotic spindle organizationGO:0000212360.035
signal transduction by phosphorylationGO:00230141070.035
intracellular receptor signaling pathwayGO:0030522190.035
microtubule cytoskeleton organization involved in mitosisGO:1902850520.035
proteolysisGO:00065081920.035
post embryonic appendage morphogenesisGO:00351203850.034
establishment or maintenance of cell polarityGO:00071631670.034
germline stem cell asymmetric divisionGO:0098728150.034
endomembrane system organizationGO:00102561190.033
regulation of cell proliferationGO:00421271630.032
cellular response to organic cyclic compoundGO:0071407320.032
response to alcoholGO:0097305950.032
cytoplasm organizationGO:0007028640.032
regulation of reproductive processGO:2000241540.032
negative regulation of cell differentiationGO:00455961430.032
regulation of alternative mrna splicing via spliceosomeGO:0000381600.032
response to organic substanceGO:00100332840.032
dorsal ventral axis specificationGO:0009950660.031
mrna splicing via spliceosomeGO:0000398730.031
cell proliferationGO:00082832990.030
regulation of secretionGO:0051046440.030
rrna processingGO:000636430.030
regulation of transportGO:00510491810.030
regulation of nuclear divisionGO:0051783580.030
negative regulation of apoptotic processGO:0043066630.030
establishment of ommatidial planar polarityGO:0042067490.030
rna phosphodiester bond hydrolysis exonucleolyticGO:009050340.029
ribonucleoside triphosphate metabolic processGO:00091991190.029
negative regulation of programmed cell deathGO:0043069720.029
protein complex biogenesisGO:00702712010.029
response to nutrient levelsGO:00316671140.028
Fly
regulation of synapse structure and activityGO:00508031280.028
dna conformation changeGO:00711031050.028
circulatory system developmentGO:0072359820.028
detection of stimulus involved in sensory perceptionGO:0050906920.028
positive regulation of macromolecule biosynthetic processGO:00105572830.028
protein modification by small protein conjugation or removalGO:00706471060.028
spermatid developmentGO:0007286980.027
Fly
positive regulation of nucleobase containing compound metabolic processGO:00459353320.027
establishment of protein localization to organelleGO:0072594620.027
purine nucleoside metabolic processGO:00422781270.027
developmental maturationGO:00217001720.027
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.027
salivary gland developmentGO:00074311620.026
germ line stem cell divisionGO:0042078250.026
positive regulation of intracellular signal transductionGO:19025331160.026
multi organism reproductive behaviorGO:00447051210.026
tube morphogenesisGO:00352391910.026
protein dna complex assemblyGO:0065004630.025
intracellular steroid hormone receptor signaling pathwayGO:0030518120.025
embryonic development via the syncytial blastodermGO:00017001480.025
heterocycle catabolic processGO:00467001660.025
defense response to bacteriumGO:00427421780.025
purine nucleotide metabolic processGO:00061631460.025
nuclear pore organizationGO:000699910.025
catabolic processGO:00090564090.024
neural retina developmentGO:000340740.024
pole plasm mrna localizationGO:0019094490.024
neuroblast proliferationGO:0007405740.024
purine containing compound metabolic processGO:00725211550.024
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.024
camera type eye developmentGO:004301040.024
protein modification processGO:00362114380.024
phosphorylationGO:00163102940.024
organelle assemblyGO:00709251980.024
appendage developmentGO:00487364010.024
locomotory behaviorGO:00076261760.023
regulation of mitotic cell cycle phase transitionGO:19019901300.023
cell growthGO:00160491080.023
maintenance of locationGO:0051235730.022
positive regulation of cellular biosynthetic processGO:00313283160.022
neuron projection guidanceGO:00974852410.022
macromolecule catabolic processGO:00090571610.022
mitotic cell cycle checkpointGO:0007093880.022
positive regulation of cellular protein metabolic processGO:00322701180.022
segmentationGO:00352822070.022
head developmentGO:00603221350.021
axis specificationGO:00097981670.021
microtubule polymerization or depolymerizationGO:0031109390.021
regulation of cell cycle processGO:00105641810.021
alcohol biosynthetic processGO:0046165140.021
rna splicing via transesterification reactionsGO:0000375730.021
response to oxygen containing compoundGO:19017002000.020
purine nucleoside triphosphate catabolic processGO:00091461080.020
purine ribonucleotide metabolic processGO:00091501450.020
covalent chromatin modificationGO:00165691060.020
production of molecular mediator of immune responseGO:0002440460.020
antimicrobial humoral responseGO:0019730990.020
mitotic g2 m transition checkpointGO:0044818700.020
protein complex assemblyGO:00064612000.020
regulation of cell shapeGO:00083601130.020
mrna splice site selectionGO:000637610.020
neurological system processGO:00508773580.019
regulation of mitosisGO:0007088560.019
intracellular signal transductionGO:00355563000.019
positive regulation of apoptotic signaling pathwayGO:200123540.019
regulation of dendrite morphogenesisGO:0048814280.019
intracellular mrna localization involved in anterior posterior axis specificationGO:0060811530.019
regulation of anatomical structure sizeGO:00900661630.019
wing disc morphogenesisGO:00074723440.019
ribonucleoprotein complex assemblyGO:0022618230.018
organophosphate catabolic processGO:00464341120.018
positive regulation of multicellular organism growthGO:0040018210.018
proteolysis involved in cellular protein catabolic processGO:0051603830.018
rna 3 end processingGO:0031123450.018
cellular response to dna damage stimulusGO:00069742230.018
regulation of cell divisionGO:0051302720.018
regulation of oskar mrna translationGO:004601180.018
negative regulation of multicellular organismal processGO:00512411420.018
ribonucleoside metabolic processGO:00091191270.018
stem cell divisionGO:0017145690.018
regulation of molecular functionGO:00650092170.017
regulation of protein localizationGO:0032880760.017
neuronal stem cell maintenanceGO:009715040.017
regulation of synapse assemblyGO:0051963940.017
rna localizationGO:00064031150.017
Human
germline ring canal formationGO:0030725130.017
defense responseGO:00069523000.017
regulation of cellular localizationGO:00603411360.017
female germ line cyst formationGO:0048135420.017
retina development in camera type eyeGO:006004140.016
aggressive behaviorGO:0002118630.016
chromatin modificationGO:00165681470.016
imaginal disc derived wing morphogenesisGO:00074763370.016
retina morphogenesis in camera type eyeGO:006004220.016
regulation of cellular component biogenesisGO:00440872010.016
maintenance of location in cellGO:0051651280.016
positive regulation of cell communicationGO:00106472500.016
posttranscriptional gene silencing by rnaGO:0035194450.016
chemotaxisGO:00069352490.015
single organism catabolic processGO:00447122280.015
brain developmentGO:00074201200.015
convergent extensionGO:006002620.015
nucleosome mobilizationGO:004276690.015
dorsal ventral pattern formation imaginal discGO:0007450510.015
nucleoside triphosphate metabolic processGO:00091411200.015
nuclear envelope organizationGO:000699870.015
negative regulation of organelle organizationGO:0010639560.015
multi organism behaviorGO:00517051750.015
nucleotide catabolic processGO:00091661090.015
kidney developmentGO:000182230.015
gland morphogenesisGO:00226121450.015
innate immune responseGO:00450871440.015
ncrna metabolic processGO:0034660430.015
cytokinesisGO:0000910900.015
regulation of chromosome organizationGO:0033044640.014
purine ribonucleoside catabolic processGO:00461301120.014
oocyte axis specificationGO:00073091080.014
regulation of behaviorGO:0050795750.014
rna phosphodiester bond hydrolysisGO:0090501170.014
stem cell proliferationGO:0072089880.014
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.014
establishment of tissue polarityGO:0007164870.014
appendage morphogenesisGO:00351073970.014
cellular homeostasisGO:0019725800.014
establishment of localization in cellGO:00516494020.013
Human
regulation of circadian rhythmGO:0042752490.013
tissue morphogenesisGO:00487292970.013
establishment of chromosome localizationGO:0051303200.013
positive regulation of growthGO:0045927750.013
hemopoiesisGO:0030097460.013
spermatogenesisGO:00072832000.013
Fly
negative regulation of cellular protein metabolic processGO:0032269850.013
positive regulation of phosphorylationGO:0042327870.013
regulation of wnt signaling pathwayGO:0030111680.013
regulation of cytoskeleton organizationGO:0051493890.013
dna recombinationGO:0006310320.013
metaphase plate congressionGO:0051310190.013
meiosis iGO:0007127590.013
dna integrity checkpointGO:0031570810.013
ribose phosphate metabolic processGO:00196931450.012
cell maturationGO:00484691440.012
cell cycle phase transitionGO:00447701400.012
renal system processGO:0003014120.012
regulation of epithelial cell differentiationGO:003085640.012
negative regulation of developmental growthGO:0048640640.012
transmembrane transportGO:00550851390.012
mapk cascadeGO:00001651070.012
regulation of intracellular signal transductionGO:19025312360.012
small gtpase mediated signal transductionGO:0007264880.012
nephron developmentGO:007200630.012
leg disc morphogenesisGO:0007478800.012
regulation of multicellular organismal developmentGO:20000264140.012
dorsal ventral axis specification ovarian follicular epitheliumGO:0008069130.012
cellular protein catabolic processGO:0044257830.012
regulation of cell cycle phase transitionGO:19019871300.012
glycosyl compound catabolic processGO:19016581120.012
intracellular transportGO:00469072280.012
Human
negative regulation of protein modification processGO:0031400290.012
synaptic transmissionGO:00072682880.012
regulation of stress activated protein kinase signaling cascadeGO:0070302420.011
regulation of oocyte developmentGO:0060281270.011
maintenance of protein locationGO:0045185280.011
protein ubiquitinationGO:0016567700.011
cytoplasmic mrna processing body assemblyGO:0033962100.011
negative regulation of cell divisionGO:0051782170.011
meiotic chromosome segregationGO:0045132590.011
forebrain developmentGO:003090020.011
wing disc pattern formationGO:0035222660.011
nucleobase containing small molecule metabolic processGO:00550861740.011
establishment of protein localizationGO:00451841630.011
regulation of multicellular organism growthGO:0040014400.011
dsrna fragmentationGO:0031050150.011
mrna 3 end processingGO:0031124280.011
g2 dna damage checkpointGO:0031572690.011
compound eye developmentGO:00487493070.011
maternal determination of anterior posterior axis embryoGO:0008358740.011
regulation of production of molecular mediator of immune responseGO:0002700440.011
oocyte microtubule cytoskeleton organizationGO:0016325350.011
proteasomal protein catabolic processGO:0010498590.011
ribonucleoside triphosphate catabolic processGO:00092031080.011
positive regulation of secretion by cellGO:1903532200.011
extracellular structure organizationGO:0043062460.011
renal system developmentGO:0072001720.011
cellular component assembly involved in morphogenesisGO:00109271510.011
negative regulation of mitotic cell cycleGO:00459301090.011
chromatin silencingGO:0006342760.011
digestive tract developmentGO:00485651490.011
sister chromatid segregationGO:0000819920.011
response to ecdysoneGO:0035075340.010
regulation of neuron deathGO:1901214260.010
positive regulation of lipid metabolic processGO:004583440.010
ecdysone receptor mediated signaling pathwayGO:0035076110.010
regulation of gene silencingGO:0060968630.010
regulation of antimicrobial humoral responseGO:0002759500.010
single organism intracellular transportGO:19025822070.010
regulation of cell growthGO:0001558430.010
ribonucleotide catabolic processGO:00092611090.010
synaptic growth at neuromuscular junctionGO:00511241190.010
regulation of mrna 3 end processingGO:003144070.010
ribonucleoside catabolic processGO:00424541120.010
embryonic hemopoiesisGO:0035162260.010
response to nitrogen compoundGO:1901698900.010
positive regulation of rna metabolic processGO:00512542710.010
blastoderm segmentationGO:00073501590.010
heart developmentGO:0007507820.010
mitotic sister chromatid segregationGO:0000070870.010
purine containing compound catabolic processGO:00725231120.010

Hrb98DE disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.117
Human
nervous system diseaseDOID:86300.110
Human
neurodegenerative diseaseDOID:128900.015
Human
central nervous system diseaseDOID:33100.015
Human
sensory system diseaseDOID:005015500.012