Drosophila melanogaster

44 known processes

dbo (Dmel_CG6224)

diablo

(Aliases: Dm.DBO,Smac,CG6224,DIABLO,Dmel\CG6224)

dbo biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
wing disc morphogenesisGO:00074723440.251
cellular catabolic processGO:00442483720.231
Human
protein modification processGO:00362114380.217
Human Fly
embryonic morphogenesisGO:00485982060.181
appendage morphogenesisGO:00351073970.177
protein localizationGO:00081042840.170
growthGO:00400073590.154
appendage developmentGO:00487364010.154
actin filament based processGO:00300292200.145
Fly
imaginal disc derived wing morphogenesisGO:00074763370.143
macromolecule catabolic processGO:00090571610.132
Human
mrna metabolic processGO:00160711240.129
actin cytoskeleton organizationGO:00300362060.109
Fly
post embryonic appendage morphogenesisGO:00351203850.097
cilium morphogenesisGO:0060271390.092
negative regulation of response to stimulusGO:00485852580.088
endocytosisGO:00068973100.083
Fly
organic substance catabolic processGO:19015753080.081
Human
positive regulation of catabolic processGO:00098961050.080
cellular macromolecule catabolic processGO:00442651360.077
Human
imaginal disc derived appendage developmentGO:00487373990.077
intracellular signal transductionGO:00355563000.075
positive regulation of rna metabolic processGO:00512542710.074
imaginal disc derived appendage morphogenesisGO:00351143950.069
heterocycle catabolic processGO:00467001660.069
regionalizationGO:00030024160.066
regulation of intracellular signal transductionGO:19025312360.065
regulation of cellular response to stressGO:0080135890.065
establishment or maintenance of cell polarityGO:00071631670.064
catabolic processGO:00090564090.063
Human
ameboidal type cell migrationGO:00016671510.063
Fly
organelle assemblyGO:00709251980.059
respiratory system developmentGO:00605412130.058
nucleobase containing compound catabolic processGO:00346551650.057
tissue morphogenesisGO:00487292970.056
rna processingGO:00063961470.053
morphogenesis of an epitheliumGO:00020092760.053
morphogenesis of a polarized epitheliumGO:0001738930.053
eye photoreceptor cell differentiationGO:00017541450.053
non sensory hair organizationGO:0035316470.052
jnk cascadeGO:0007254500.051
cellular macromolecule localizationGO:00707272200.051
positive regulation of signal transductionGO:00099672230.050
positive regulation of response to stimulusGO:00485843230.050
digestive system developmentGO:00551231490.050
regulation of mrna metabolic processGO:1903311720.048
rubidium ion transportGO:003582610.048
establishment of localization in cellGO:00516494020.048
Human
organelle localizationGO:00516401480.047
phosphorylationGO:00163102940.046
positive regulation of cell communicationGO:00106472500.045
body morphogenesisGO:001017120.044
modification dependent macromolecule catabolic processGO:0043632790.044
Human
posttranscriptional regulation of gene expressionGO:00106081450.043
response to organic substanceGO:00100332840.042
cell divisionGO:00513012480.041
rna catabolic processGO:0006401370.041
positive regulation of signalingGO:00230562430.041
cellular macromolecular complex assemblyGO:00346221530.041
actin filament organizationGO:00070151260.040
embryonic axis specificationGO:00005781070.039
chromosome segregationGO:00070591570.039
regulation of mrna processingGO:0050684710.039
cellular protein localizationGO:00346131600.038
establishment of planar polarityGO:0001736870.038
establishment of cell polarityGO:0030010400.037
establishment or maintenance of apical basal cell polarityGO:0035088340.037
regulation of response to stressGO:00801342000.036
stress activated protein kinase signaling cascadeGO:0031098550.036
compound eye developmentGO:00487493070.036
macromolecular complex assemblyGO:00650032560.035
regulation of protein metabolic processGO:00512462560.034
Fly
mrna processingGO:00063971040.033
open tracheal system developmentGO:00074242040.033
regulation of cellular component biogenesisGO:00440872010.032
cell recognitionGO:00080371020.032
negative regulation of cellular component organizationGO:00511291080.032
establishment of monopolar cell polarityGO:0061162150.032
establishment of organelle localizationGO:00516561220.032
regulation of cytoskeleton organizationGO:0051493890.032
cell migrationGO:00164772380.031
Fly
limb morphogenesisGO:003510810.031
rrna processingGO:000636430.031
embryonic development via the syncytial blastodermGO:00017001480.031
regulation of cell cell adhesionGO:0022407210.031
regulation of anatomical structure sizeGO:00900661630.031
regulation of organelle organizationGO:00330431960.031
synaptic target recognitionGO:0008039450.030
phagocytosisGO:00069092150.030
Fly
rna splicingGO:0008380830.029
protein ubiquitinationGO:0016567700.029
Human Fly
organic cyclic compound catabolic processGO:19013611680.029
regulation of multicellular organismal developmentGO:20000264140.029
positive regulation of macromolecule metabolic processGO:00106044050.029
Fly
cellular nitrogen compound catabolic processGO:00442701650.029
single organism intracellular transportGO:19025822070.028
Human
establishment of tissue polarityGO:0007164870.028
segmentationGO:00352822070.028
extracellular matrix constituent secretionGO:007027840.027
limb developmentGO:006017310.027
regulation of establishment of planar polarityGO:0090175220.027
cell cell adhesion via plasma membrane adhesion moleculesGO:0098742260.027
mrna catabolic processGO:0006402330.026
embryonic pattern specificationGO:00098801740.026
regulation of proteolysisGO:0030162870.026
Fly
positive regulation of gene expressionGO:00106282900.026
negative regulation of gene expressionGO:00106293870.025
regulation of wnt signaling pathwayGO:0030111680.024
spermatid developmentGO:0007286980.024
Fly
regulation of phosphorylationGO:00423251470.024
proteolysisGO:00065081920.024
Human Fly
proteasomal protein catabolic processGO:0010498590.024
Human
male gamete generationGO:00482322010.024
Fly
establishment of protein localizationGO:00451841630.023
stress activated mapk cascadeGO:0051403520.023
cellular response to peptideGO:1901653280.023
positive regulation of proteolysisGO:0045862520.023
Fly
transcription from rna polymerase ii promoterGO:00063663680.023
protein transportGO:00150311550.023
central nervous system developmentGO:00074172010.023
ubiquitin dependent protein catabolic processGO:0006511780.023
Human
multi organism behaviorGO:00517051750.023
imaginal disc derived wing hair organizationGO:0035317450.023
establishment or maintenance of monopolar cell polarityGO:0061339150.023
regulation of cell morphogenesisGO:00226041630.023
modification dependent protein catabolic processGO:0019941780.023
Human
positive regulation of nucleobase containing compound metabolic processGO:00459353320.023
regulation of phosphorus metabolic processGO:00511742100.022
cellular response to dna damage stimulusGO:00069742230.022
imaginal disc derived wing vein morphogenesisGO:0008586440.022
establishment of epithelial cell apical basal polarityGO:0045198100.022
cellular protein modification processGO:00064644380.022
Human Fly
positive regulation of cellular catabolic processGO:0031331950.021
gene silencingGO:00164581380.021
positive regulation of transcription dna templatedGO:00458932660.021
spindle organizationGO:00070512530.021
anterior posterior axis specificationGO:00099481090.021
regulation of transcription from rna polymerase ii promoterGO:00063573780.021
o glycan processingGO:001626630.021
convergent extensionGO:006002620.021
establishment or maintenance of bipolar cell polarityGO:0061245340.021
regulation of cellular protein metabolic processGO:00322682430.021
Fly
aromatic compound catabolic processGO:00194391660.021
regulation of cellular component sizeGO:0032535980.021
mapk cascadeGO:00001651070.021
biological adhesionGO:00226101380.020
oligosaccharide metabolic processGO:0009311180.020
regulation of jnk cascadeGO:0046328400.020
anterior posterior pattern specificationGO:00099521360.020
protein modification by small protein conjugationGO:0032446790.020
Human Fly
regulation of localizationGO:00328792750.020
carbohydrate biosynthetic processGO:0016051170.019
cell cell adhesionGO:0098609260.019
posttranscriptional gene silencing by rnaGO:0035194450.019
signal transduction by phosphorylationGO:00230141070.019
negative regulation of cell communicationGO:00106482230.019
nuclear transcribed mrna catabolic processGO:0000956240.019
sensory perception of chemical stimulusGO:00076061160.019
regulation of notch signaling pathwayGO:00085931000.019
ribonucleoprotein complex subunit organizationGO:0071826280.019
notch signaling pathwayGO:00072191200.018
negative regulation of signal transductionGO:00099682060.018
establishment or maintenance of epithelial cell apical basal polarityGO:0045197240.018
response to abiotic stimulusGO:00096283410.018
dorsal ventral pattern formationGO:00099531330.018
wnt signaling pathwayGO:0016055980.017
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052240.017
neuron recognitionGO:00080381010.017
tube morphogenesisGO:00352391910.017
cilium organizationGO:0044782410.017
blastoderm segmentationGO:00073501590.017
developmental growthGO:00485892800.017
rhythmic processGO:00485111060.017
circadian sleep wake cycle sleepGO:0050802230.017
chemosensory behaviorGO:00076351060.016
compound eye photoreceptor developmentGO:0042051780.016
negative regulation of signalingGO:00230572190.016
response to radiationGO:00093141550.016
hair cell differentiationGO:0035315470.016
cell adhesionGO:00071551360.016
segment polarity determinationGO:0007367250.016
rna localizationGO:00064031150.016
negative regulation of cell proliferationGO:0008285690.016
nuclear divisionGO:00002803320.016
epithelial cell developmentGO:00020642740.016
Fly
establishment of imaginal disc derived wing hair orientationGO:0001737240.016
positive regulation of nucleic acid templated transcriptionGO:19035082660.016
endosomal transportGO:0016197440.016
Human
negative regulation of wnt signaling pathwayGO:0030178280.015
epithelial cell migrationGO:00106311480.015
Fly
regulation of alternative mrna splicing via spliceosomeGO:0000381600.015
positive regulation of intracellular signal transductionGO:19025331160.015
ribonucleoprotein complex biogenesisGO:0022613310.015
cellular protein catabolic processGO:0044257830.015
Human
protein depolymerizationGO:0051261310.015
cellular protein complex disassemblyGO:0043624350.015
cell cell signaling involved in cell fate commitmentGO:00451682100.015
cytoplasmic transportGO:00164821300.015
Human
protein catabolic processGO:00301631010.015
Human
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377730.015
deathGO:00162652840.015
Human Fly
regulation of stress activated mapk cascadeGO:0032872410.015
digestive tract developmentGO:00485651490.015
regulation of rna splicingGO:0043484690.015
eye developmentGO:00016543230.015
ribonucleoprotein complex assemblyGO:0022618230.015
positive regulation of proteasomal protein catabolic processGO:1901800200.014
response to biotic stimulusGO:00096072940.014
mrna splicing via spliceosomeGO:0000398730.014
regulation of tube size open tracheal systemGO:0035151430.014
inter male aggressive behaviorGO:0002121600.014
response to external biotic stimulusGO:00432072930.014
neurological system processGO:00508773580.014
regulation of actin cytoskeleton organizationGO:0032956420.014
vesicle mediated transportGO:00161923810.014
Human Fly
nuclear transportGO:0051169720.014
endomembrane system organizationGO:00102561190.014
intracellular transportGO:00469072280.014
Human
regulation of phosphate metabolic processGO:00192202100.014
olfactory behaviorGO:0042048970.014
intracellular protein transportGO:00068861040.014
epidermal cell differentiationGO:0009913510.013
tripartite regional subdivisionGO:00073511030.013
cellular response to organonitrogen compoundGO:0071417360.013
erbb signaling pathwayGO:0038127580.013
enzyme linked receptor protein signaling pathwayGO:00071671790.013
regulation of epidermal growth factor receptor signaling pathwayGO:0042058420.013
digestive tract morphogenesisGO:00485461270.013
germarium derived egg chamber formationGO:00072931010.013
Fly
positive regulation of catalytic activityGO:00430851180.013
Fly
negative regulation of organelle organizationGO:0010639560.013
eye morphogenesisGO:00485922600.013
protein targetingGO:0006605640.013
regulation of catalytic activityGO:00507901850.013
Fly
reproductive structure developmentGO:0048608740.013
cell migration involved in gastrulationGO:004207490.013
ncrna processingGO:0034470300.013
alternative mrna splicing via spliceosomeGO:0000380600.012
cell deathGO:00082192790.012
Human Fly
photoreceptor cell developmentGO:0042461960.012
asymmetric protein localizationGO:0008105330.012
vesicle organizationGO:0016050440.012
homophilic cell adhesion via plasma membrane adhesion moleculesGO:0007156180.012
proteolysis involved in cellular protein catabolic processGO:0051603830.012
Human
oligosaccharide biosynthetic processGO:0009312100.012
imaginal disc derived wing vein specificationGO:0007474480.012
regulation of tube length open tracheal systemGO:0035159240.012
motor neuron axon guidanceGO:0008045580.012
smoothened signaling pathwayGO:0007224490.012
regulation of epithelial cell proliferationGO:005067840.012
positive regulation of cellular protein metabolic processGO:00322701180.012
Fly
humoral immune responseGO:00069591170.012
positive regulation of phosphorylationGO:0042327870.012
regulation of cell shapeGO:00083601130.012
epithelium migrationGO:00901321480.012
Fly
cellular component assembly involved in morphogenesisGO:00109271510.012
protein complex biogenesisGO:00702712010.012
compound eye photoreceptor cell differentiationGO:00017511400.012
single organism cell adhesionGO:0098602470.012
defense responseGO:00069523000.012
antimicrobial humoral responseGO:0019730990.012
pigmentationGO:0043473750.012
regulation of growthGO:00400082330.012
regulation of stress activated protein kinase signaling cascadeGO:0070302420.012
protein complex assemblyGO:00064612000.012
embryo development ending in birth or egg hatchingGO:00097921520.012
chromosome organizationGO:00512763600.012
Fly
positive regulation of phosphate metabolic processGO:00459371390.012
spermatid differentiationGO:00485151140.011
Fly
regulation of mrna splicing via spliceosomeGO:0048024640.011
positive regulation of mapk cascadeGO:0043410630.011
single organism behaviorGO:00447083910.011
negative regulation of epithelial cell proliferationGO:005068040.011
single organism cellular localizationGO:19025801800.011
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436190.011
anterior posterior axis specification embryoGO:00085951030.011
cellular response to chemical stimulusGO:00708871990.011
carboxylic acid metabolic processGO:0019752920.011
rna splicing via transesterification reactionsGO:0000375730.011
single organism catabolic processGO:00447122280.011
negative regulation of notch signaling pathwayGO:0045746410.011
actin filament bundle organizationGO:0061572280.011
aggressive behaviorGO:0002118630.011
notch receptor processingGO:0007220130.011
imaginal disc derived wing margin morphogenesisGO:0008587410.010
tube developmentGO:00352952440.010
regulation of cellular response to growth factor stimulusGO:0090287130.010
regulation of gene expression epigeneticGO:00400291280.010
response to organonitrogen compoundGO:0010243750.010
oxoacid metabolic processGO:00434361030.010
imaginal disc derived wing hair site selectionGO:003532040.010
small molecule metabolic processGO:00442813050.010
ommatidial rotationGO:0016318200.010
regulation of protein catabolic processGO:0042176550.010
positive regulation of rna biosynthetic processGO:19026802660.010
regulation of protein modification by small protein conjugation or removalGO:1903320250.010
regulation of protein modification processGO:00313991120.010
lateral inhibitionGO:00463312060.010
epidermal growth factor receptor signaling pathwayGO:0007173580.010
imaginal disc derived leg morphogenesisGO:0007480800.010
organelle fissionGO:00482853400.010
carbohydrate derivative metabolic processGO:19011352170.010
retina development in camera type eyeGO:006004140.010
regulation of organ morphogenesisGO:2000027780.010

dbo disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.014
disease of anatomical entityDOID:700.012
nervous system diseaseDOID:86300.012
disease of cellular proliferationDOID:1456600.010
cancerDOID:16200.010
organ system cancerDOID:005068600.010