IMP: Integrative Multi-species Prediction

Drosophila melanogaster

107 known processes

disco (Dmel_CG9908)

disconnected

(Aliases: disc,Dmel\CG9908,CG9908,Disco)

Entrez: 32579
FLYBASE: FBgn0000459
UniProtKB: P23792

Process Predictions
Disease Predictions

disco biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
eye development	GO:0001654	323	0.955
compound eye morphogenesis	GO:0001745	249	0.947
chemotaxis	GO:0006935	249	0.894
eye morphogenesis	GO:0048592	260	0.852
negative regulation of gene expression	GO:0010629	387	0.815
regionalization	GO:0003002	416	0.788
regulation of neuron differentiation	GO:0045664	103	0.766
axon development	GO:0061564	297	0.757
positive regulation of macromolecule metabolic process	GO:0010604	405	0.738
axon guidance	GO:0007411	233	0.723
regulation of cell differentiation	GO:0045595	302	0.721
negative regulation of transcription dna templated	GO:0045892	237	0.714
central nervous system development	GO:0007417	201	0.689
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.670
photoreceptor cell differentiation	GO:0046530	170	0.667
regulation of multicellular organismal development	GO:2000026	414	0.667
signal release	GO:0023061	49	0.665
tissue morphogenesis	GO:0048729	297	0.641
regulation of nervous system development	GO:0051960	248	0.634
regulation of cell development	GO:0060284	215	0.633
cell motility	GO:0048870	251	0.626
taxis	GO:0042330	304	0.616
locomotory behavior	GO:0007626	176	0.616
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.606
axonogenesis	GO:0007409	290	0.598
photoreceptor cell development	GO:0042461	96	0.590
response to organic substance	GO:0010033	284	0.587
epithelial cell differentiation	GO:0030855	322	0.585
embryo development ending in birth or egg hatching	GO:0009792	152	0.583
neurological system process	GO:0050877	358	0.569
positive regulation of transcription dna templated	GO:0045893	266	0.569
compound eye development	GO:0048749	307	0.560
negative regulation of cellular metabolic process	GO:0031324	382	0.547
tube development	GO:0035295	244	0.545
regulation of neurogenesis	GO:0050767	158	0.529
eye photoreceptor cell development	GO:0042462	81	0.522
single organism behavior	GO:0044708	391	0.515
eye photoreceptor cell differentiation	GO:0001754	145	0.513
localization of cell	GO:0051674	257	0.512
malpighian tubule morphogenesis	GO:0007443	44	0.508
cell fate specification	GO:0001708	71	0.507
sensory perception	GO:0007600	196	0.497
programmed cell death	GO:0012501	257	0.487
regulation of anatomical structure morphogenesis	GO:0022603	242	0.477
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.476
sensory organ morphogenesis	GO:0090596	260	0.472
death	GO:0016265	284	0.464
malpighian tubule development	GO:0072002	64	0.450
morphogenesis of embryonic epithelium	GO:0016331	94	0.440
negative regulation of rna metabolic process	GO:0051253	251	0.417
negative regulation of rna biosynthetic process	GO:1902679	240	0.417
cell proliferation	GO:0008283	299	0.413	Mouse
dendrite development	GO:0016358	204	0.408
growth	GO:0040007	359	0.406	Mouse
regulation of cell morphogenesis	GO:0022604	163	0.396
learning or memory	GO:0007611	141	0.396
tissue migration	GO:0090130	155	0.392
dendrite morphogenesis	GO:0048813	199	0.390
renal tubule development	GO:0061326	64	0.387
secretion	GO:0046903	109	0.371
negative regulation of biosynthetic process	GO:0009890	277	0.367
circadian rhythm	GO:0007623	105	0.365
digestive tract morphogenesis	GO:0048546	127	0.358
nephron morphogenesis	GO:0072028	3	0.356
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.341
neuron projection guidance	GO:0097485	241	0.330
positive regulation of rna metabolic process	GO:0051254	271	0.326
immune response	GO:0006955	246	0.325
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.324
tube morphogenesis	GO:0035239	191	0.320
cellular protein modification process	GO:0006464	438	0.315
negative regulation of cellular biosynthetic process	GO:0031327	277	0.312
ovarian follicle cell development	GO:0030707	248	0.312
positive regulation of biosynthetic process	GO:0009891	316	0.312
embryonic development via the syncytial blastoderm	GO:0001700	148	0.306
adult behavior	GO:0030534	137	0.303
cell migration	GO:0016477	238	0.298
neuron recognition	GO:0008038	101	0.296
regulation of molecular function	GO:0065009	217	0.293
regulation of organ morphogenesis	GO:2000027	78	0.291
muscle organ development	GO:0007517	127	0.279
regulation of cell morphogenesis involved in differentiation	GO:0010769	61	0.278
chromatin organization	GO:0006325	207	0.277
compound eye photoreceptor development	GO:0042051	78	0.275
columnar cuboidal epithelial cell development	GO:0002066	249	0.274
positive regulation of gene expression	GO:0010628	290	0.268
negative regulation of cell communication	GO:0010648	223	0.268
neuron fate commitment	GO:0048663	50	0.266
dorsal ventral pattern formation	GO:0009953	133	0.258
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.258
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.254
regulation of behavior	GO:0050795	75	0.252
border follicle cell migration	GO:0007298	113	0.252
negative regulation of signaling	GO:0023057	219	0.250
positive regulation of cellular biosynthetic process	GO:0031328	316	0.247
response to gravity	GO:0009629	26	0.240
response to alcohol	GO:0097305	95	0.240
embryonic morphogenesis	GO:0048598	206	0.239
developmental growth	GO:0048589	280	0.233	Mouse
compound eye photoreceptor cell differentiation	GO:0001751	140	0.222
epithelial cell development	GO:0002064	274	0.220
positive regulation of rna biosynthetic process	GO:1902680	266	0.220
ameboidal type cell migration	GO:0001667	151	0.215
positive regulation of cell differentiation	GO:0045597	64	0.215
regulation of epithelial cell proliferation	GO:0050678	4	0.212	Mouse
catabolic process	GO:0009056	409	0.212
cell fate determination	GO:0001709	91	0.211
regulation of protein metabolic process	GO:0051246	256	0.208
chromosome organization	GO:0051276	360	0.207	Mouse
photoreceptor cell fate commitment	GO:0046552	41	0.207
renal tubule morphogenesis	GO:0061333	44	0.203
cardiac cell fate commitment	GO:0060911	17	0.202
dna metabolic process	GO:0006259	227	0.201
chromatin modification	GO:0016568	147	0.199
protein modification process	GO:0036211	438	0.197
axon choice point recognition	GO:0016198	26	0.195
regulation of r7 cell differentiation	GO:0045676	15	0.193
negative regulation of cell differentiation	GO:0045596	143	0.190
regulation of cellular protein metabolic process	GO:0032268	243	0.190
regulation of embryonic development	GO:0045995	68	0.189
kidney development	GO:0001822	3	0.188
negative regulation of response to stimulus	GO:0048585	258	0.184
hindgut morphogenesis	GO:0007442	58	0.183
regulation of localization	GO:0032879	275	0.183
aggressive behavior	GO:0002118	63	0.182
organelle fission	GO:0048285	340	0.180
epithelial tube morphogenesis	GO:0060562	88	0.180
digestive system development	GO:0055123	149	0.177
regulation of catalytic activity	GO:0050790	185	0.177
cellular ketone metabolic process	GO:0042180	24	0.175
positive regulation of molecular function	GO:0044093	136	0.174
small molecule metabolic process	GO:0044281	305	0.173
nephron epithelium development	GO:0072009	3	0.172
response to oxygen containing compound	GO:1901700	200	0.171
regulation of phosphorus metabolic process	GO:0051174	210	0.171
homeostatic process	GO:0042592	199	0.171
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.170
r7 cell differentiation	GO:0045466	43	0.167
muscle structure development	GO:0061061	224	0.166
female genitalia development	GO:0030540	6	0.165
epithelial cell proliferation	GO:0050673	15	0.164	Mouse
compound eye cone cell fate commitment	GO:0042676	5	0.163
regulation of cell cycle	GO:0051726	291	0.162
nephron tubule morphogenesis	GO:0072078	3	0.162
connective tissue development	GO:0061448	3	0.159
positive regulation of phosphate metabolic process	GO:0045937	139	0.159
rhythmic process	GO:0048511	106	0.158
regulation of cellular component biogenesis	GO:0044087	201	0.157
response to organic cyclic compound	GO:0014070	89	0.157
immune system process	GO:0002376	347	0.156
regulation of cell death	GO:0010941	173	0.155
digestive tract development	GO:0048565	149	0.154
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.153
regulation of organelle organization	GO:0033043	196	0.151
morphogenesis of a branching epithelium	GO:0061138	45	0.149
epithelium migration	GO:0090132	148	0.149
circadian behavior	GO:0048512	76	0.148
gastrulation	GO:0007369	70	0.148
regulation of cell fate commitment	GO:0010453	29	0.148
secretion by cell	GO:0032940	101	0.146
epithelial cell migration	GO:0010631	148	0.144
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.143
regulation of photoreceptor cell differentiation	GO:0046532	34	0.142
neuron fate specification	GO:0048665	12	0.139
regulation of cell fate specification	GO:0042659	27	0.139
positive regulation of endopeptidase activity	GO:0010950	26	0.137
behavioral response to ethanol	GO:0048149	49	0.137
rhythmic behavior	GO:0007622	76	0.133
positive regulation of cell proliferation	GO:0008284	47	0.133	Mouse
cell junction organization	GO:0034330	57	0.131
negative regulation of multicellular organismal process	GO:0051241	142	0.131
cellular catabolic process	GO:0044248	372	0.128
response to lipid	GO:0033993	38	0.127
sex differentiation	GO:0007548	81	0.126
cell division	GO:0051301	248	0.126
organic acid metabolic process	GO:0006082	103	0.126
regulation of heart morphogenesis	GO:2000826	3	0.124
cognition	GO:0050890	141	0.124
cell adhesion	GO:0007155	136	0.123
branching morphogenesis of an epithelial tube	GO:0048754	45	0.122
head development	GO:0060322	135	0.120
imaginal disc derived female genitalia development	GO:0007486	6	0.120
regulation of mitotic cell cycle	GO:0007346	190	0.119
regulation of phosphate metabolic process	GO:0019220	210	0.119
immune response regulating signaling pathway	GO:0002764	2	0.118
regulation of hydrolase activity	GO:0051336	97	0.116
developmental programmed cell death	GO:0010623	138	0.116
response to sterol	GO:0036314	34	0.113
terminal region determination	GO:0007362	25	0.112
cellular homeostasis	GO:0019725	80	0.112
regulation of hormone levels	GO:0010817	40	0.112
kidney morphogenesis	GO:0060993	3	0.110
regulation of response to external stimulus	GO:0032101	115	0.110
striated muscle tissue development	GO:0014706	27	0.109
positive regulation of multicellular organismal process	GO:0051240	143	0.108
dendrite guidance	GO:0070983	21	0.108
circulatory system development	GO:0072359	82	0.108
regulation of cellular localization	GO:0060341	136	0.107
mushroom body development	GO:0016319	70	0.107
positive regulation of axonogenesis	GO:0050772	2	0.107
compound eye cone cell differentiation	GO:0042675	13	0.106
regulation of cellular ketone metabolic process	GO:0010565	3	0.104
salivary gland development	GO:0007431	162	0.102
response to bacterium	GO:0009617	198	0.102
organic cyclic compound catabolic process	GO:1901361	168	0.102
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.102
camera type eye morphogenesis	GO:0048593	2	0.100
cell cell junction organization	GO:0045216	55	0.098
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.096
regulation of apoptotic process	GO:0042981	130	0.096
negative regulation of neurogenesis	GO:0050768	53	0.095
kidney epithelium development	GO:0072073	3	0.094
eye photoreceptor cell fate commitment	GO:0042706	37	0.094
amine metabolic process	GO:0009308	12	0.093
positive regulation of cellular protein metabolic process	GO:0032270	118	0.092
protein complex assembly	GO:0006461	200	0.092
regulation of peptide secretion	GO:0002791	6	0.092
olfactory behavior	GO:0042048	97	0.091
negative regulation of molecular function	GO:0044092	51	0.090
ribose phosphate metabolic process	GO:0019693	145	0.090
actin filament based process	GO:0030029	220	0.089
mitotic nuclear division	GO:0007067	213	0.088
organic substance catabolic process	GO:1901575	308	0.088
positive regulation of protein metabolic process	GO:0051247	128	0.085
negative regulation of signal transduction	GO:0009968	206	0.085
compound eye photoreceptor fate commitment	GO:0001752	36	0.083
immune response activating signal transduction	GO:0002757	2	0.083
positive regulation of cell development	GO:0010720	61	0.083
gene silencing	GO:0016458	138	0.082
regulation of neuron projection development	GO:0010975	69	0.082
apoptotic process	GO:0006915	159	0.081
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.080
positive regulation of cellular component biogenesis	GO:0044089	80	0.080
cardiovascular system development	GO:0072358	82	0.080
organ formation	GO:0048645	39	0.079
covalent chromatin modification	GO:0016569	106	0.079
ribonucleoside catabolic process	GO:0042454	112	0.079
actin cytoskeleton organization	GO:0030036	206	0.078
regulation of response to stress	GO:0080134	200	0.075
regulation of secretion	GO:0051046	44	0.075
cellular response to oxygen containing compound	GO:1901701	79	0.075
gland development	GO:0048732	191	0.075
male gamete generation	GO:0048232	201	0.074
cell death	GO:0008219	279	0.074
biological adhesion	GO:0022610	138	0.074
urogenital system development	GO:0001655	72	0.073
gonad development	GO:0008406	50	0.073
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.073
protein phosphorylation	GO:0006468	169	0.072
regulation of epithelial cell differentiation	GO:0030856	4	0.070
peptidyl amino acid modification	GO:0018193	105	0.070
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.070
response to abiotic stimulus	GO:0009628	341	0.069
synapse assembly	GO:0007416	143	0.069
cell junction assembly	GO:0034329	42	0.069
regulation of catabolic process	GO:0009894	170	0.068
camera type eye development	GO:0043010	4	0.068
imaginal disc pattern formation	GO:0007447	91	0.068
rho protein signal transduction	GO:0007266	14	0.067
skeletal muscle organ development	GO:0060538	48	0.067
female sex differentiation	GO:0046660	20	0.066
purine ribonucleotide catabolic process	GO:0009154	109	0.066
eye antennal disc morphogenesis	GO:0007455	34	0.066
retina development in camera type eye	GO:0060041	4	0.065
positive regulation of phosphorus metabolic process	GO:0010562	139	0.065
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.065
lateral inhibition	GO:0046331	206	0.065
nucleoside metabolic process	GO:0009116	127	0.064
establishment of ommatidial planar polarity	GO:0042067	49	0.064
regulation of immune system process	GO:0002682	176	0.064
transcription from rna polymerase ii promoter	GO:0006366	368	0.063
renal system development	GO:0072001	72	0.063
reproductive system development	GO:0061458	74	0.062
outflow tract morphogenesis	GO:0003151	4	0.062
mesenchymal cell differentiation	GO:0048762	1	0.062
peptidyl lysine acetylation	GO:0018394	39	0.061
regulation of cell cycle process	GO:0010564	181	0.061
exocrine system development	GO:0035272	162	0.061
response to extracellular stimulus	GO:0009991	116	0.060
cellular amino acid metabolic process	GO:0006520	61	0.060
negative regulation of cell proliferation	GO:0008285	69	0.059
regulation of cell proliferation	GO:0042127	163	0.058	Mouse
endocytosis	GO:0006897	310	0.058
negative regulation of cell death	GO:0060548	81	0.057
organonitrogen compound metabolic process	GO:1901564	318	0.057
negative regulation of nervous system development	GO:0051961	92	0.056
limb development	GO:0060173	1	0.056
ras protein signal transduction	GO:0007265	88	0.055
torso signaling pathway	GO:0008293	21	0.055
anterior posterior pattern specification	GO:0009952	136	0.055
neuroblast differentiation	GO:0014016	29	0.055
spermatogenesis	GO:0007283	200	0.054
dorsal closure	GO:0007391	79	0.054
purine ribonucleotide metabolic process	GO:0009150	145	0.054
positive regulation of compound eye retinal cell programmed cell death	GO:0046672	9	0.053
nucleoside triphosphate metabolic process	GO:0009141	120	0.053
positive regulation of developmental process	GO:0051094	143	0.053
cellular response to organic substance	GO:0071310	132	0.052
carboxylic acid metabolic process	GO:0019752	92	0.052
salivary gland morphogenesis	GO:0007435	145	0.051
forebrain development	GO:0030900	2	0.051
response to biotic stimulus	GO:0009607	294	0.051
regulation of protein modification process	GO:0031399	112	0.051
carbohydrate derivative metabolic process	GO:1901135	217	0.051
regulation of circadian rhythm	GO:0042752	49	0.051
nucleobase containing small molecule metabolic process	GO:0055086	174	0.051
mating behavior sex discrimination	GO:0048047	7	0.051
response to lipopolysaccharide	GO:0032496	4	0.051
axon midline choice point recognition	GO:0016199	26	0.051
positive regulation of catalytic activity	GO:0043085	118	0.050
positive regulation of programmed cell death	GO:0043068	62	0.050
cell recognition	GO:0008037	102	0.050
ovarian follicle cell migration	GO:0007297	121	0.050
regulation of cellular response to stress	GO:0080135	89	0.049
regulation of cellular amino acid metabolic process	GO:0006521	0	0.049
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.049
muscle cell fate commitment	GO:0042693	14	0.048
single organismal cell cell adhesion	GO:0016337	45	0.048
axis specification	GO:0009798	167	0.048
positive regulation of response to external stimulus	GO:0032103	44	0.048
morphogenesis of an epithelium	GO:0002009	276	0.048
negative regulation of cellular component organization	GO:0051129	108	0.047
positive regulation of rho gtpase activity	GO:0032321	19	0.047
stem cell differentiation	GO:0048863	117	0.046
positive regulation of signaling	GO:0023056	243	0.046
anterior posterior pattern specification imaginal disc	GO:0007448	16	0.046
embryonic pattern specification	GO:0009880	174	0.046
positive regulation of hydrolase activity	GO:0051345	78	0.045
organic hydroxy compound biosynthetic process	GO:1901617	21	0.045
regulation of cell projection organization	GO:0031344	92	0.045
histone modification	GO:0016570	106	0.045
male courtship behavior	GO:0008049	63	0.045
regulation of peptide hormone secretion	GO:0090276	5	0.044
organonitrogen compound biosynthetic process	GO:1901566	117	0.044
regulation of peptidase activity	GO:0052547	39	0.044
protein complex biogenesis	GO:0070271	201	0.043
cell type specific apoptotic process	GO:0097285	38	0.043
positive regulation of nucleotide metabolic process	GO:0045981	55	0.043
phosphorylation	GO:0016310	294	0.043
regulation of intracellular signal transduction	GO:1902531	236	0.042
morphogenesis of a branching structure	GO:0001763	45	0.042
entrainment of circadian clock	GO:0009649	16	0.042
purine containing compound metabolic process	GO:0072521	155	0.042
regulation of dendrite morphogenesis	GO:0048814	28	0.042
regulation of muscle organ development	GO:0048634	13	0.041
nephron development	GO:0072006	3	0.041
response to endogenous stimulus	GO:0009719	119	0.041
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.040
regulation of cellular amine metabolic process	GO:0033238	3	0.040
regulation of purine nucleotide metabolic process	GO:1900542	62	0.040
regulation of programmed cell death	GO:0043067	152	0.040
g protein coupled receptor signaling pathway	GO:0007186	136	0.040
cellular response to biotic stimulus	GO:0071216	4	0.040
regulation of axonogenesis	GO:0050770	32	0.040
skeletal muscle fiber development	GO:0048741	3	0.039
cellular response to carbohydrate stimulus	GO:0071322	4	0.039
purine nucleotide metabolic process	GO:0006163	146	0.039
positive regulation of response to stimulus	GO:0048584	323	0.039
histone acetylation	GO:0016573	38	0.038
positive regulation of purine nucleotide metabolic process	GO:1900544	55	0.038
proteolysis	GO:0006508	192	0.038
heart development	GO:0007507	82	0.037
macromolecular complex assembly	GO:0065003	256	0.037
establishment or maintenance of cell polarity	GO:0007163	167	0.037
regulation of secretion by cell	GO:1903530	39	0.037
nephron tubule development	GO:0072080	3	0.037
nuclear division	GO:0000280	332	0.036
purine ribonucleoside metabolic process	GO:0046128	127	0.036
regulation of immune response	GO:0050776	118	0.036
peptidyl lysine modification	GO:0018205	57	0.036
reproductive structure development	GO:0048608	74	0.036
establishment of localization in cell	GO:0051649	402	0.036
protein acetylation	GO:0006473	39	0.036
regulation of dendrite development	GO:0050773	37	0.035
regulation of gene expression epigenetic	GO:0040029	128	0.035
morphogenesis of a polarized epithelium	GO:0001738	93	0.035
negative regulation of apoptotic process	GO:0043066	63	0.035
negative regulation of developmental process	GO:0051093	201	0.035
ecdysone mediated induction of salivary gland cell autophagic cell death	GO:0035072	12	0.035
positive regulation of nucleoside metabolic process	GO:0045979	47	0.034
anterior posterior axis specification embryo	GO:0008595	103	0.034
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.033
retinal cone cell differentiation	GO:0042670	2	0.033
brain development	GO:0007420	120	0.033
regulation of cellular catabolic process	GO:0031329	157	0.033
protein modification by small protein conjugation or removal	GO:0070647	106	0.033
vesicle mediated transport	GO:0016192	381	0.033
gastrulation involving germ band extension	GO:0010004	36	0.033
intracellular signal transduction	GO:0035556	300	0.032
smoothened signaling pathway	GO:0007224	49	0.032
regulation of phosphorylation	GO:0042325	147	0.032
regulation of endopeptidase activity	GO:0052548	36	0.032
positive regulation of cellular component organization	GO:0051130	156	0.032
cellular response to chemical stimulus	GO:0070887	199	0.032
response to external biotic stimulus	GO:0043207	293	0.032
muscle tissue development	GO:0060537	30	0.032
notch signaling pathway	GO:0007219	120	0.032
nephrocyte diaphragm assembly	GO:0036059	3	0.031
nucleoside phosphate metabolic process	GO:0006753	162	0.031
lipid metabolic process	GO:0006629	121	0.031
spinal cord development	GO:0021510	1	0.031
specification of organ identity	GO:0010092	3	0.030
mesodermal cell fate specification	GO:0007501	2	0.030
organophosphate metabolic process	GO:0019637	195	0.030
carbohydrate derivative biosynthetic process	GO:1901137	85	0.030
positive regulation of cellular amine metabolic process	GO:0033240	0	0.030
single organism catabolic process	GO:0044712	228	0.030
stem cell proliferation	GO:0072089	88	0.029
zygotic determination of anterior posterior axis embryo	GO:0007354	27	0.029
eye antennal disc development	GO:0035214	60	0.029
single organism biosynthetic process	GO:0044711	206	0.029
determination of dorsal ventral asymmetry	GO:0048262	3	0.029
regulation of transport	GO:0051049	181	0.029
cellular protein complex assembly	GO:0043623	71	0.029
courtship behavior	GO:0007619	68	0.029
regulation of cell division	GO:0051302	72	0.028
regulation of nuclear division	GO:0051783	58	0.028
cell growth	GO:0016049	108	0.028
chemical homeostasis	GO:0048878	92	0.028
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.028
establishment of planar polarity	GO:0001736	87	0.028
female gonad development	GO:0008585	12	0.028
dna replication	GO:0006260	48	0.028
nephron epithelium morphogenesis	GO:0072088	3	0.027
nucleoside phosphate catabolic process	GO:1901292	110	0.027
compound eye retinal cell programmed cell death	GO:0046667	23	0.027
positive regulation of signal transduction	GO:0009967	223	0.027
regulation of actin filament based process	GO:0032970	42	0.027
positive regulation of axon guidance	GO:1902669	1	0.027
cuticle development	GO:0042335	86	0.027
gland morphogenesis	GO:0022612	145	0.027
ribonucleotide metabolic process	GO:0009259	145	0.027
developmental maturation	GO:0021700	172	0.026
nucleoside triphosphate catabolic process	GO:0009143	108	0.026
internal protein amino acid acetylation	GO:0006475	38	0.026
pigmentation	GO:0043473	75	0.026	Zebrafish
cellular response to mechanical stimulus	GO:0071260	2	0.026
male courtship behavior veined wing extension	GO:0048065	22	0.026
regulation of compound eye cone cell fate specification	GO:0042682	4	0.025
multicellular organismal reproductive behavior	GO:0033057	110	0.025
response to monosaccharide	GO:0034284	4	0.025
adult chitin based cuticle pattern formation	GO:0035018	1	0.025
positive regulation of neuron differentiation	GO:0045666	26	0.025
skeletal muscle tissue development	GO:0007519	13	0.025
body morphogenesis	GO:0010171	2	0.025
carbohydrate homeostasis	GO:0033500	12	0.025
carbohydrate derivative catabolic process	GO:1901136	118	0.025
induction of programmed cell death by hormones	GO:0035081	12	0.024
ventral cord development	GO:0007419	16	0.024
embryonic hindgut morphogenesis	GO:0048619	48	0.024
appendage morphogenesis	GO:0035107	397	0.024
regulation of ras protein signal transduction	GO:0046578	93	0.024
gonad morphogenesis	GO:0035262	7	0.024
neuron remodeling	GO:0016322	29	0.024
negative regulation of insulin secretion	GO:0046676	1	0.024
synaptic transmission	GO:0007268	288	0.024
regulation of dna metabolic process	GO:0051052	34	0.024
positive regulation of epithelial cell differentiation	GO:0030858	1	0.024
positive regulation of retinal cell programmed cell death	GO:0046670	9	0.024
mesoderm development	GO:0007498	78	0.024
positive regulation of locomotion	GO:0040017	8	0.023
anatomical structure homeostasis	GO:0060249	97	0.023
glycosyl compound catabolic process	GO:1901658	112	0.023
negative regulation of cellular protein metabolic process	GO:0032269	85	0.023
regulation of defense response	GO:0031347	102	0.023
inter male aggressive behavior	GO:0002121	60	0.023
peptide hormone secretion	GO:0030072	5	0.023
protein acylation	GO:0043543	42	0.023
protein localization	GO:0008104	284	0.023
dorsal appendage formation	GO:0046843	47	0.023
negative regulation of catalytic activity	GO:0043086	42	0.023
immune effector process	GO:0002252	98	0.022
ribonucleotide catabolic process	GO:0009261	109	0.022
negative regulation of hormone biosynthetic process	GO:0032353	1	0.022
positive regulation of cell cycle	GO:0045787	43	0.022
cellular response to lipid	GO:0071396	20	0.022
neuroblast fate commitment	GO:0014017	19	0.022
negative regulation of cell fate specification	GO:0009996	15	0.022
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.022
negative regulation of programmed cell death	GO:0043069	72	0.022
negative regulation of growth	GO:0045926	84	0.022
larval development	GO:0002164	104	0.022
nucleotide catabolic process	GO:0009166	109	0.021
regulation of embryonic cell shape	GO:0016476	30	0.021
gastrulation with mouth forming first	GO:0001703	36	0.021
endocrine system development	GO:0035270	5	0.021
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	65	0.021
regulation of growth	GO:0040008	233	0.021
intracellular receptor signaling pathway	GO:0030522	19	0.021
neuroblast fate specification	GO:0014018	2	0.021
camera type eye photoreceptor cell differentiation	GO:0060219	2	0.021
protein modification by small protein conjugation	GO:0032446	79	0.021
protein maturation	GO:0051604	71	0.021

disco disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.170
cardiovascular system disease	DOID:1287	0.126
urinary system disease	DOID:18	0.040
disease of cellular proliferation	DOID:14566	0.039
cancer	DOID:162	0.039
organ system cancer	DOID:0050686	0.039

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