IMP: Integrative Multi-species Prediction

Drosophila melanogaster

21 known processes

Nnp-1 (Dmel_CG12396)

CG12396 gene product from transcript CG12396-RA

(Aliases: Nnp1,l(2)k07826,Dmel\CG12396,CG12396,NNP-1,nnp-1)

Entrez: 44391
FLYBASE: FBgn0022069
UniProtKB: Q9VJZ7

Process Predictions
Disease Predictions

Nnp-1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
mitotic spindle organization	GO:0007052	220	0.160
rrna processing	GO:0006364	3	0.148
cell migration	GO:0016477	238	0.124
embryo development ending in birth or egg hatching	GO:0009792	152	0.105
determination of adult lifespan	GO:0008340	137	0.101
vesicle mediated transport	GO:0016192	381	0.083
body morphogenesis	GO:0010171	2	0.081
rna processing	GO:0006396	147	0.065
single organism intracellular transport	GO:1902582	207	0.062
endocytosis	GO:0006897	310	0.061
ribonucleoprotein complex biogenesis	GO:0022613	31	0.060
apoptotic process	GO:0006915	159	0.059
organelle assembly	GO:0070925	198	0.054
cellular macromolecular complex assembly	GO:0034622	153	0.053
protein transport	GO:0015031	155	0.053
larval development	GO:0002164	104	0.051
mitotic spindle elongation	GO:0000022	81	0.051
multicellular organismal aging	GO:0010259	140	0.047
cytoplasmic transport	GO:0016482	130	0.044
small molecule metabolic process	GO:0044281	305	0.043
regulation of developmental growth	GO:0048638	174	0.043
localization of cell	GO:0051674	257	0.041
developmental growth	GO:0048589	280	0.039
cell growth	GO:0016049	108	0.038
protein modification process	GO:0036211	438	0.037
programmed cell death	GO:0012501	257	0.036
ribosomal large subunit biogenesis	GO:0042273	1	0.036
aging	GO:0007568	143	0.035
cell motility	GO:0048870	251	0.035
ncrna metabolic process	GO:0034660	43	0.035
ribosome biogenesis	GO:0042254	8	0.034
regulation of programmed cell death	GO:0043067	152	0.033
spindle assembly	GO:0051225	80	0.031
organic substance transport	GO:0071702	257	0.031
multi multicellular organism process	GO:0044706	123	0.031
nucleobase containing compound catabolic process	GO:0034655	165	0.031
regulation of cell cycle process	GO:0010564	181	0.030
posttranscriptional gene silencing by rna	GO:0035194	45	0.030
rna catabolic process	GO:0006401	37	0.029
cell proliferation	GO:0008283	299	0.029
positive regulation of signaling	GO:0023056	243	0.029
negative regulation of cell death	GO:0060548	81	0.029
cellular macromolecule localization	GO:0070727	220	0.029
spindle organization	GO:0007051	253	0.028
establishment of protein localization	GO:0045184	163	0.027
negative regulation of cellular metabolic process	GO:0031324	382	0.027
intracellular protein transport	GO:0006886	104	0.025
response to biotic stimulus	GO:0009607	294	0.025
regulation of cell cycle	GO:0051726	291	0.024
rna splicing	GO:0008380	83	0.024
rna interference	GO:0016246	27	0.023
cellular protein localization	GO:0034613	160	0.022
growth	GO:0040007	359	0.021
rna polyadenylation	GO:0043631	12	0.021
organic substance catabolic process	GO:1901575	308	0.021
protein localization to organelle	GO:0033365	82	0.021
regulation of growth	GO:0040008	233	0.021
cell death	GO:0008219	279	0.020
epithelial cell differentiation	GO:0030855	322	0.019
catabolic process	GO:0009056	409	0.019
imaginal disc derived wing morphogenesis	GO:0007476	337	0.019
multicellular organismal reproductive behavior	GO:0033057	110	0.018
negative regulation of mitotic cell cycle	GO:0045930	109	0.018
regulation of neuron differentiation	GO:0045664	103	0.018
nucleocytoplasmic transport	GO:0006913	72	0.018
nuclear export	GO:0051168	24	0.017
immune system process	GO:0002376	347	0.017
intracellular transport	GO:0046907	228	0.017
macromolecular complex assembly	GO:0065003	256	0.017
protein localization to nucleus	GO:0034504	55	0.017
cell division	GO:0051301	248	0.017
reproductive structure development	GO:0048608	74	0.017
nuclear transport	GO:0051169	72	0.016
stem cell maintenance	GO:0019827	67	0.016
nucleoside phosphate metabolic process	GO:0006753	162	0.016
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.016
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.016
regulation of cell proliferation	GO:0042127	163	0.016
death	GO:0016265	284	0.016
regulation of cell death	GO:0010941	173	0.016
regulation of nervous system development	GO:0051960	248	0.016
post embryonic appendage morphogenesis	GO:0035120	385	0.016
microtubule organizing center organization	GO:0031023	168	0.016
ribonucleoprotein complex localization	GO:0071166	2	0.015
negative regulation of gene expression	GO:0010629	387	0.015
imaginal disc derived appendage development	GO:0048737	399	0.015
defense response to other organism	GO:0098542	225	0.015
purine nucleotide metabolic process	GO:0006163	146	0.015
positive regulation of biosynthetic process	GO:0009891	316	0.015
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.015
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.015
ribonucleoprotein complex subunit organization	GO:0071826	28	0.014
mrna metabolic process	GO:0016071	124	0.014
positive regulation of protein transport	GO:0051222	37	0.014
negative regulation of cell cycle	GO:0045786	116	0.014
carbohydrate derivative metabolic process	GO:1901135	217	0.014
regulation of mrna splicing via spliceosome	GO:0048024	64	0.014
sex differentiation	GO:0007548	81	0.014
single organism cellular localization	GO:1902580	180	0.014
reproductive system development	GO:0061458	74	0.014
establishment of organelle localization	GO:0051656	122	0.014
carboxylic acid metabolic process	GO:0019752	92	0.014
heterocycle catabolic process	GO:0046700	166	0.014
regulation of meiosis	GO:0040020	3	0.013
positive regulation of cell migration	GO:0030335	2	0.013
nucleolus organization	GO:0007000	4	0.013
protein targeting	GO:0006605	64	0.013
organonitrogen compound metabolic process	GO:1901564	318	0.013
regulation of cell differentiation	GO:0045595	302	0.013
positive regulation of rna metabolic process	GO:0051254	271	0.013
gene silencing by rna	GO:0031047	57	0.013
regulation of phosphorus metabolic process	GO:0051174	210	0.013
genital disc development	GO:0035215	44	0.013
oxoacid metabolic process	GO:0043436	103	0.012
regulation of mitotic cell cycle	GO:0007346	190	0.012
mrna processing	GO:0006397	104	0.012
protein localization	GO:0008104	284	0.012
positive regulation of developmental process	GO:0051094	143	0.012
organelle localization	GO:0051640	148	0.012
response to bacterium	GO:0009617	198	0.012
cellular nitrogen compound catabolic process	GO:0044270	165	0.012
gene silencing	GO:0016458	138	0.012
receptor mediated endocytosis	GO:0006898	21	0.012
cellular response to chemical stimulus	GO:0070887	199	0.011
positive regulation of signal transduction	GO:0009967	223	0.011
posttranscriptional gene silencing	GO:0016441	46	0.011
positive regulation of transport	GO:0051050	92	0.011
regulation of cell growth	GO:0001558	43	0.011
imaginal disc growth	GO:0007446	37	0.011
protein import into nucleus	GO:0006606	51	0.011
dna damage checkpoint	GO:0000077	78	0.011
chromosome organization	GO:0051276	360	0.011
negative regulation of cell communication	GO:0010648	223	0.011
regulation of apoptotic process	GO:0042981	130	0.011
appendage development	GO:0048736	401	0.011
positive regulation of response to stimulus	GO:0048584	323	0.011
negative regulation of growth	GO:0045926	84	0.011
positive regulation of cell motility	GO:2000147	3	0.011
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.011
response to other organism	GO:0051707	293	0.010
positive regulation of multicellular organismal process	GO:0051240	143	0.010
phosphorylation	GO:0016310	294	0.010
rna splicing via transesterification reactions	GO:0000375	73	0.010
eye morphogenesis	GO:0048592	260	0.010
negative regulation of cell cycle process	GO:0010948	109	0.010
centrosome cycle	GO:0007098	137	0.010
protein targeting to nucleus	GO:0044744	51	0.010
organic cyclic compound catabolic process	GO:1901361	168	0.010

Nnp-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
cancer	DOID:162	0.032
organ system cancer	DOID:0050686	0.032
disease of cellular proliferation	DOID:14566	0.032
disease of anatomical entity	DOID:7	0.026
nervous system disease	DOID:863	0.016

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