Drosophila melanogaster

164 known processes

Trl (Dmel_CG33261)

Trithorax-like

(Aliases: Trl-GAGA,Adf-2-519,trl,Gaf,CG9343,l(3)s2325,Adf-2,E(var)3-trl,gaga,TfGAGA/Adf-2,Adf2,anon-EST:fe2E12,TRL,E(var)62,GAGA,Gaga,Dmel\CG33261,GAF,Nc70F,CG33261,NC70F)

Trl biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regionalizationGO:00030024160.996
Fly
negative regulation of biosynthetic processGO:00098902770.994
negative regulation of cellular biosynthetic processGO:00313272770.989
negative regulation of nucleobase containing compound metabolic processGO:00459342610.964
epithelial cell developmentGO:00020642740.948
Fly
ovarian follicle cell developmentGO:00307072480.948
Fly
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.938
meiotic cell cycle processGO:19030461320.895
Fly
negative regulation of macromolecule biosynthetic processGO:00105582700.851
negative regulation of nitrogen compound metabolic processGO:00511722650.816
positive regulation of biosynthetic processGO:00098913160.796
negative regulation of gene expressionGO:00106293870.756
negative regulation of transcription dna templatedGO:00458922370.682
dorsal ventral pattern formationGO:00099531330.681
anterior posterior pattern specificationGO:00099521360.650
Fly
cognitionGO:00508901410.629
negative regulation of cellular metabolic processGO:00313243820.593
meiosis iGO:0007127590.566
Fly
regulation of cell differentiationGO:00455953020.565
Fly
multi organism behaviorGO:00517051750.537
Fly
morphogenesis of follicular epitheliumGO:0016333360.533
neuron projection guidanceGO:00974852410.518
Fly
negative regulation of cell communicationGO:00106482230.511
vesicle mediated transportGO:00161923810.464
embryonic axis specificationGO:00005781070.454
Fly
positive regulation of macromolecule metabolic processGO:00106044050.431
epithelial cell differentiationGO:00308553220.430
Fly
positive regulation of nitrogen compound metabolic processGO:00511733540.391
positive regulation of rna metabolic processGO:00512542710.382
negative regulation of signal transductionGO:00099682060.373
regulation of cellular component biogenesisGO:00440872010.345
positive regulation of transcription dna templatedGO:00458932660.336
columnar cuboidal epithelial cell developmentGO:00020662490.308
Fly
dendrite morphogenesisGO:00488131990.297
Fly
ovarian follicle cell migrationGO:00072971210.284
Fly
anterior posterior axis specificationGO:00099481090.283
Fly
positive regulation of macromolecule biosynthetic processGO:00105572830.264
dendrite developmentGO:00163582040.264
Fly
tripartite regional subdivisionGO:00073511030.254
Fly
spermatogenesisGO:00072832000.254
negative regulation of response to stimulusGO:00485852580.252
oocyte constructionGO:00073081120.246
germarium derived egg chamber formationGO:00072931010.245
negative regulation of nucleic acid templated transcriptionGO:19035072400.231
chromatin silencingGO:0006342760.228
head developmentGO:00603221350.219
Fly
muscle cell differentiationGO:00426921030.212
Fly
positive regulation of response to stimulusGO:00485843230.208
axis specificationGO:00097981670.208
Fly
appendage developmentGO:00487364010.185
leg disc morphogenesisGO:0007478800.184
columnar cuboidal epithelial cell differentiationGO:00020652560.183
Fly
positive regulation of gene expressionGO:00106282900.178
gene silencingGO:00164581380.175
tissue deathGO:00162711020.159
Fly
chemotaxisGO:00069352490.158
Fly
developmental programmed cell deathGO:00106231380.147
Fly
regulation of multicellular organismal developmentGO:20000264140.133
Fly
brain developmentGO:00074201200.130
Fly
chromatin remodelingGO:0006338720.128
regulation of reproductive processGO:2000241540.124
axonogenesisGO:00074092900.104
Fly
germarium derived female germ line cyst encapsulationGO:003070880.102
regulation of chromatin silencingGO:0031935360.100
negative regulation of gene expression epigeneticGO:0045814770.100
meiotic cell cycleGO:00513211710.100
Fly
positive regulation of nucleobase containing compound metabolic processGO:00459353320.096
negative regulation of rna metabolic processGO:00512532510.087
regulation of transcription from rna polymerase ii promoterGO:00063573780.086
embryonic pattern specificationGO:00098801740.079
Fly
negative regulation of developmental processGO:00510932010.077
organonitrogen compound metabolic processGO:19015643180.072
chitin based cuticle developmentGO:0040003490.070
Fly
learningGO:0007612750.070
small molecule metabolic processGO:00442813050.068
imaginal disc derived appendage morphogenesisGO:00351143950.067
wing disc morphogenesisGO:00074723440.067
tissue morphogenesisGO:00487292970.059
Fly
cell cycle comprising mitosis without cytokinesisGO:0033301250.059
developmental growthGO:00485892800.055
Fly
learning or memoryGO:00076111410.053
cytoplasmic transportGO:00164821300.052
cell maturationGO:00484691440.052
cellular response to chemical stimulusGO:00708871990.052
Fly
segmentationGO:00352822070.052
Fly
cellular response to oxygen containing compoundGO:1901701790.051
Fly
dna metabolic processGO:00062592270.051
dna alkylationGO:000630540.050
salivary gland histolysisGO:0035070880.049
Fly
positive regulation of cellular protein metabolic processGO:00322701180.048
appendage morphogenesisGO:00351073970.048
membrane organizationGO:00610241120.047
spermatid differentiationGO:00485151140.046
positive regulation of cellular component organizationGO:00511301560.045
female germ line cyst encapsulationGO:004813980.045
positive regulation of signal transductionGO:00099672230.045
morphogenesis of an epitheliumGO:00020092760.045
Fly
blastoderm segmentationGO:00073501590.044
Fly
gland developmentGO:00487321910.044
Fly
regulation of protein metabolic processGO:00512462560.043
negative regulation of cellular component organizationGO:00511291080.042
cuticle developmentGO:0042335860.041
Fly
intracellular transportGO:00469072280.041
imaginal disc derived wing vein specificationGO:0007474480.041
protein localizationGO:00081042840.041
Fly
male meiosisGO:0007140520.040
Fly
dna methylationGO:000630640.040
organelle inheritanceGO:004830820.040
eggshell chorion assemblyGO:0007306660.040
Fly
oocyte differentiationGO:00099941450.039
anterior posterior axis specification embryoGO:00085951030.038
Fly
regulation of localizationGO:00328792750.038
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.038
Fly
response to nutrient levelsGO:00316671140.038
regulation of anatomical structure sizeGO:00900661630.038
Fly
oocyte developmentGO:00485991240.037
positive regulation of multicellular organismal processGO:00512401430.036
imaginal disc pattern formationGO:0007447910.036
endomembrane system organizationGO:00102561190.035
endocytosisGO:00068973100.035
developmental maturationGO:00217001720.035
positive regulation of nucleic acid templated transcriptionGO:19035082660.034
histone acetylationGO:0016573380.033
transcription from rna polymerase ii promoterGO:00063663680.033
single organism cellular localizationGO:19025801800.033
purine ribonucleoside triphosphate metabolic processGO:00092051190.032
negative regulation of rna biosynthetic processGO:19026792400.031
negative regulation of signalingGO:00230572190.031
salivary gland morphogenesisGO:00074351450.030
Fly
regulation of multi organism processGO:00439001310.030
catabolic processGO:00090564090.030
Fly
apoptotic processGO:00069151590.030
Fly
eye developmentGO:00016543230.029
Fly
dna methylation or demethylationGO:004472840.029
neurological system processGO:00508773580.028
Fly
positive regulation of protein metabolic processGO:00512471280.028
hematopoietic or lymphoid organ developmentGO:0048534570.028
growthGO:00400073590.027
Fly
single organism intracellular transportGO:19025822070.026
imaginal disc derived appendage developmentGO:00487373990.025
response to organic cyclic compoundGO:0014070890.025
Fly
eggshell formationGO:00307031050.024
Fly
single organism behaviorGO:00447083910.024
Fly
memoryGO:0007613940.024
oocyte axis specificationGO:00073091080.023
sex determinationGO:0007530180.022
peptidyl lysine acetylationGO:0018394390.022
humoral immune responseGO:00069591170.022
Fly
regulation of cellular component sizeGO:0032535980.021
amine metabolic processGO:0009308120.020
oocyte anterior posterior axis specificationGO:0007314720.020
deathGO:00162652840.020
Fly
cellular protein modification processGO:00064644380.019
programmed cell deathGO:00125012570.019
Fly
leg disc developmentGO:0035218920.019
dorsal ventral pattern formation imaginal discGO:0007450510.019
positive regulation of rna biosynthetic processGO:19026802660.019
cell cycle phase transitionGO:00447701400.018
positive regulation of cell differentiationGO:0045597640.018
multi multicellular organism processGO:00447061230.018
border follicle cell migrationGO:00072981130.018
Fly
regulation of developmental growthGO:00486381740.018
homeostatic processGO:00425921990.018
cellular response to organic cyclic compoundGO:0071407320.018
Fly
establishment of localization in cellGO:00516494020.018
forebrain developmentGO:003090020.018
male meiosis iGO:000714190.017
Fly
protein modification processGO:00362114380.017
positive regulation of cellular biosynthetic processGO:00313283160.017
cellular protein localizationGO:00346131600.017
regulation of viral genome replicationGO:004506940.016
positive regulation of phosphorylationGO:0042327870.016
oocyte microtubule cytoskeleton organizationGO:0016325350.016
cell proliferationGO:00082832990.016
positive regulation of organelle organizationGO:0010638650.015
positive regulation of transferase activityGO:0051347260.015
antimicrobial humoral responseGO:0019730990.015
Fly
meiotic chromosome segregationGO:0045132590.015
Fly
response to oxygen containing compoundGO:19017002000.015
Fly
wing disc pattern formationGO:0035222660.015
imaginal disc derived wing morphogenesisGO:00074763370.014
regulation of oocyte developmentGO:0060281270.014
axon guidanceGO:00074112330.014
Fly
central nervous system developmentGO:00074172010.014
Fly
regulation of phosphatase activityGO:001092130.014
nucleoside phosphate metabolic processGO:00067531620.014
regulation of wnt signaling pathwayGO:0030111680.013
ribose phosphate metabolic processGO:00196931450.013
organelle fissionGO:00482853400.013
germ line cyst encapsulationGO:004813880.013
histolysisGO:00075591020.013
Fly
chorion containing eggshell formationGO:00073041050.013
Fly
regulation of pole plasm oskar mrna localizationGO:0007317270.013
oocyte dorsal ventral axis specificationGO:0007310340.013
regulation of intracellular signal transductionGO:19025312360.013
positive regulation of cell communicationGO:00106472500.013
actin filament organizationGO:00070151260.012
regulation of membrane potentialGO:0042391350.012
positive regulation of developmental processGO:00510941430.012
negative regulation of cell differentiationGO:00455961430.012
purine ribonucleoside metabolic processGO:00461281270.012
immune system developmentGO:0002520570.012
dorsal ventral axis specification ovarian follicular epitheliumGO:0008069130.012
ribonucleoside triphosphate metabolic processGO:00091991190.012
synaptic transmissionGO:00072682880.012
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.012
oocyte nucleus localization involved in oocyte dorsal ventral axis specificationGO:0051663120.012
organic substance transportGO:00717022570.011
establishment or maintenance of cell polarityGO:00071631670.011
Fly
embryo development ending in birth or egg hatchingGO:00097921520.011
Fly
negative regulation of protein metabolic processGO:0051248850.011
purine containing compound metabolic processGO:00725211550.011
protein localization to organelleGO:0033365820.011
regulation of hemocyte proliferationGO:0035206370.011
protein transportGO:00150311550.011
compound eye photoreceptor cell differentiationGO:00017511400.011
Fly
response to woundingGO:0009611940.011
negative regulation of transcription factor import into nucleusGO:004299240.010
cellular amino acid metabolic processGO:0006520610.010
regulation of cell developmentGO:00602842150.010
actin filament bundle organizationGO:0061572280.010
hormone metabolic processGO:0042445330.010

Trl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
bone development diseaseDOID:008000600.018
bone diseaseDOID:008000100.018
disease of anatomical entityDOID:700.018
connective tissue diseaseDOID:6500.018
musculoskeletal system diseaseDOID:1700.018
osteochondrodysplasiaDOID:225600.018
osteogenesis imperfectaDOID:1234700.018
meningiomaDOID:356500.016
organ system cancerDOID:005068600.016
disease of cellular proliferationDOID:1456600.016
familial meningiomaDOID:458600.016
cancerDOID:16200.016
nervous system cancerDOID:309300.016
central nervous system cancerDOID:362000.016