Drosophila melanogaster

77 known processes

tow (Dmel_CG14821)

target of wingless

(Aliases: CG14821,Dmel\CG14821)

tow biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
tissue morphogenesisGO:00487292970.831
appendage developmentGO:00487364010.394
positive regulation of macromolecule metabolic processGO:00106044050.348
regulation of multicellular organismal developmentGO:20000264140.341
eggshell chorion assemblyGO:0007306660.338
establishment of planar polarityGO:0001736870.315
appendage morphogenesisGO:00351073970.284
wing disc morphogenesisGO:00074723440.214
post embryonic appendage morphogenesisGO:00351203850.143
regulation of organ morphogenesisGO:2000027780.142
imaginal disc derived appendage developmentGO:00487373990.137
morphogenesis of a polarized epitheliumGO:0001738930.129
negative regulation of signal transductionGO:00099682060.125
negative regulation of transcription dna templatedGO:00458922370.116
positive regulation of response to stimulusGO:00485843230.114
endocytosisGO:00068973100.108
negative regulation of nucleic acid templated transcriptionGO:19035072400.106
eggshell formationGO:00307031050.101
smoothened signaling pathwayGO:0007224490.100
imaginal disc derived appendage morphogenesisGO:00351143950.094
negative regulation of biosynthetic processGO:00098902770.094
chorion containing eggshell formationGO:00073041050.091
neuron recognitionGO:00080381010.085
negative regulation of cellular metabolic processGO:00313243820.084
establishment of tissue polarityGO:0007164870.083
neurological system processGO:00508773580.083
dendrite morphogenesisGO:00488131990.079
locomotory behaviorGO:00076261760.071
spinal cord developmentGO:002151010.071
negative regulation of rna biosynthetic processGO:19026792400.070
regulation of cell differentiationGO:00455953020.069
regulation of mitotic cell cycleGO:00073461900.068
morphogenesis of an epitheliumGO:00020092760.066
negative regulation of macromolecule biosynthetic processGO:00105582700.066
nucleotide catabolic processGO:00091661090.065
vesicle mediated transportGO:00161923810.062
positive regulation of cell migrationGO:003033520.061
dendrite developmentGO:00163582040.061
epithelial cell differentiationGO:00308553220.060
regulation of cell developmentGO:00602842150.060
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.060
single organism behaviorGO:00447083910.060
small molecule metabolic processGO:00442813050.059
negative regulation of nitrogen compound metabolic processGO:00511722650.058
regulation of anatomical structure morphogenesisGO:00226032420.057
negative regulation of cellular biosynthetic processGO:00313272770.057
negative regulation of signalingGO:00230572190.056
positive regulation of nucleobase containing compound metabolic processGO:00459353320.056
regulation of notch signaling pathwayGO:00085931000.054
regulation of localizationGO:00328792750.053
ovarian follicle cell developmentGO:00307072480.052
sensory organ morphogenesisGO:00905962600.052
negative regulation of rna metabolic processGO:00512532510.052
positive regulation of multicellular organismal processGO:00512401430.050
protein phosphorylationGO:00064681690.049
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.049
organonitrogen compound metabolic processGO:19015643180.047
metal ion transportGO:0030001740.047
chemotaxisGO:00069352490.046
phosphorylationGO:00163102940.046
regulation of anatomical structure sizeGO:00900661630.046
purine containing compound catabolic processGO:00725231120.046
positive regulation of developmental processGO:00510941430.045
circulatory system processGO:0003013370.045
regulation of molecular functionGO:00650092170.044
regulation of cell cycleGO:00517262910.043
positive regulation of gene expressionGO:00106282900.043
cation transportGO:00068121100.043
compound eye photoreceptor cell differentiationGO:00017511400.043
regulation of protein metabolic processGO:00512462560.043
purine nucleoside triphosphate catabolic processGO:00091461080.042
regulation of programmed cell deathGO:00430671520.041
cellular nitrogen compound catabolic processGO:00442701650.041
cellular component assembly involved in morphogenesisGO:00109271510.041
negative regulation of developmental processGO:00510932010.040
blood circulationGO:0008015260.040
skeletal muscle organ developmentGO:0060538480.040
protein complex biogenesisGO:00702712010.039
phagocytosisGO:00069092150.039
peptidyl threonine phosphorylationGO:001810720.039
positive regulation of cell motilityGO:200014730.039
positive regulation of macromolecule biosynthetic processGO:00105572830.039
endomembrane system organizationGO:00102561190.038
regulation of transportGO:00510491810.038
regulation of smoothened signaling pathwayGO:0008589280.038
rho protein signal transductionGO:0007266140.038
detection of light stimulusGO:0009583580.037
cell divisionGO:00513012480.037
imaginal disc derived wing vein specificationGO:0007474480.036
positive regulation of molecular functionGO:00440931360.036
response to abiotic stimulusGO:00096283410.036
imaginal disc derived wing morphogenesisGO:00074763370.035
homeostatic processGO:00425921990.035
epithelial cell migrationGO:00106311480.035
positive regulation of cell communicationGO:00106472500.035
eye morphogenesisGO:00485922600.035
transcription from rna polymerase ii promoterGO:00063663680.034
enzyme linked receptor protein signaling pathwayGO:00071671790.034
purine ribonucleotide catabolic processGO:00091541090.034
wnt signaling pathwayGO:0016055980.033
regulation of apoptotic processGO:00429811300.033
spinal cord patterningGO:002151110.033
cellular response to carbohydrate stimulusGO:007132240.033
amine metabolic processGO:0009308120.032
positive regulation of transcription dna templatedGO:00458932660.032
localization of cellGO:00516742570.032
negative regulation of cell communicationGO:00106482230.031
macromolecular complex assemblyGO:00650032560.031
axis specificationGO:00097981670.031
negative regulation of gene expressionGO:00106293870.031
positive regulation of signal transductionGO:00099672230.031
notch signaling pathwayGO:00072191200.031
cell cell adhesionGO:0098609260.031
positive regulation of cellular component organizationGO:00511301560.031
small gtpase mediated signal transductionGO:0007264880.031
compound eye morphogenesisGO:00017452490.030
positive regulation of nitrogen compound metabolic processGO:00511733540.030
camera type eye developmentGO:004301040.030
regulation of cellular amine metabolic processGO:003323830.029
dorsal appendage formationGO:0046843470.029
detection of external stimulusGO:0009581660.029
developmental maturationGO:00217001720.029
purine nucleoside metabolic processGO:00422781270.028
multi organism behaviorGO:00517051750.028
regulation of cellular amino acid metabolic processGO:000652100.028
immune response activating signal transductionGO:000275720.028
regulation of blood circulationGO:1903522210.028
adult behaviorGO:00305341370.028
catabolic processGO:00090564090.028
regulation of nervous system developmentGO:00519602480.028
organic cyclic compound catabolic processGO:19013611680.028
nucleoside triphosphate catabolic processGO:00091431080.027
developmental growthGO:00485892800.027
cellular catabolic processGO:00442483720.027
neuron projection guidanceGO:00974852410.027
positive regulation of rna biosynthetic processGO:19026802660.027
cellular response to chemical stimulusGO:00708871990.027
positive regulation of nucleic acid templated transcriptionGO:19035082660.027
positive regulation of cellular biosynthetic processGO:00313283160.027
regulation of cellular response to growth factor stimulusGO:0090287130.027
response to organophosphorusGO:004668320.026
tube developmentGO:00352952440.026
eye photoreceptor cell differentiationGO:00017541450.026
heart contractionGO:0060047260.026
regulation of wound healingGO:0061041130.025
negative regulation of phosphorus metabolic processGO:0010563450.025
epithelial cell developmentGO:00020642740.024
ion transportGO:00068111450.024
cellular macromolecule localizationGO:00707272200.024
regulation of phosphorylationGO:00423251470.024
ribonucleotide metabolic processGO:00092591450.024
spinal cord dorsal ventral patterningGO:002151310.024
phototransductionGO:0007602520.024
tissue migrationGO:00901301550.023
regulation of organelle organizationGO:00330431960.023
aromatic compound catabolic processGO:00194391660.023
negative regulation of nucleobase containing compound metabolic processGO:00459342610.023
positive regulation of rna metabolic processGO:00512542710.023
muscle cell differentiationGO:00426921030.023
g protein coupled receptor signaling pathwayGO:00071861360.023
golgi organizationGO:0007030660.023
regulation of epithelial cell proliferationGO:005067840.023
protein modification processGO:00362114380.022
regulation of i kappab kinase nf kappab signalingGO:004312220.022
regulation of growthGO:00400082330.022
nuclear divisionGO:00002803320.022
epidermal growth factor receptor signaling pathwayGO:0007173580.022
photoreceptor cell differentiationGO:00465301700.022
positive regulation of proteolysisGO:0045862520.022
cell cycle phase transitionGO:00447701400.022
cell motilityGO:00488702510.022
striated muscle cell differentiationGO:0051146900.022
establishment or maintenance of cell polarityGO:00071631670.022
nucleoside triphosphate metabolic processGO:00091411200.022
chemical homeostasisGO:0048878920.021
cellular homeostasisGO:0019725800.021
nucleoside phosphate catabolic processGO:19012921100.021
ras protein signal transductionGO:0007265880.021
purine ribonucleoside triphosphate catabolic processGO:00092071080.021
nucleobase containing compound catabolic processGO:00346551650.021
wound healingGO:0042060750.020
cell deathGO:00082192790.020
ribonucleotide catabolic processGO:00092611090.020
chitin based cuticle developmentGO:0040003490.020
posttranscriptional regulation of gene expressionGO:00106081450.020
regionalizationGO:00030024160.020
regulation of cellular component sizeGO:0032535980.020
cell junction assemblyGO:0034329420.020
single organism catabolic processGO:00447122280.020
positive regulation of biosynthetic processGO:00098913160.020
cellular response to oxygen containing compoundGO:1901701790.020
gtp metabolic processGO:0046039720.020
ion homeostasisGO:0050801550.020
organelle assemblyGO:00709251980.020
immune response regulating signaling pathwayGO:000276420.020
negative regulation of response to stimulusGO:00485852580.020
regulation of cell migrationGO:0030334220.020
positive regulation of gtpase activityGO:0043547430.019
molting cycle processGO:0022404290.019
regulation of catalytic activityGO:00507901850.019
organonitrogen compound catabolic processGO:19015651280.019
regulation of phosphate metabolic processGO:00192202100.019
positive regulation of cellular component biogenesisGO:0044089800.019
cell migrationGO:00164772380.019
positive regulation of hydrolase activityGO:0051345780.019
carbohydrate derivative metabolic processGO:19011352170.019
molting cycleGO:0042303560.019
proteolysisGO:00065081920.019
negative regulation of nervous system developmentGO:0051961920.018
positive regulation of phosphorus metabolic processGO:00105621390.018
oocyte developmentGO:00485991240.018
cell cell junction organizationGO:0045216550.018
negative regulation of intracellular signal transductionGO:1902532570.018
peptidyl threonine modificationGO:001821030.018
cellular amine metabolic processGO:0044106120.018
regulation of cellular protein metabolic processGO:00322682430.018
regulation of cell proliferationGO:00421271630.018
nucleobase containing small molecule metabolic processGO:00550861740.018
purine nucleoside catabolic processGO:00061521120.018
organic substance transportGO:00717022570.018
skeletal muscle fiber developmentGO:004874130.018
establishment of ommatidial planar polarityGO:0042067490.018
programmed cell deathGO:00125012570.018
nucleoside catabolic processGO:00091641120.018
regulation of hydrolase activityGO:0051336970.017
regulation of purine nucleotide metabolic processGO:1900542620.017
oocyte differentiationGO:00099941450.017
cellular response to organic substanceGO:00713101320.017
organophosphate catabolic processGO:00464341120.017
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.017
regulation of epidermal growth factor receptor signaling pathwayGO:0042058420.017
neural retina developmentGO:000340740.016
axon guidanceGO:00074112330.016
ribonucleoside metabolic processGO:00091191270.016
head developmentGO:00603221350.016
eye photoreceptor cell fate commitmentGO:0042706370.016
cell cell junction assemblyGO:0007043380.016
myotube cell developmentGO:001490430.016
mitotic cell cycle phase transitionGO:00447721380.016
regulation of cellular component biogenesisGO:00440872010.016
somatic muscle developmentGO:0007525660.016
regulation of neuron projection developmentGO:0010975690.016
purine ribonucleoside catabolic processGO:00461301120.016
positive regulation of catalytic activityGO:00430851180.016
regulation of heart contractionGO:0008016210.016
columnar cuboidal epithelial cell differentiationGO:00020652560.016
negative regulation of cell proliferationGO:0008285690.016
protein complex assemblyGO:00064612000.016
hindbrain developmentGO:003090220.016
cellular protein catabolic processGO:0044257830.016
response to endogenous stimulusGO:00097191190.016
glycosyl compound metabolic processGO:19016571270.015
erbb signaling pathwayGO:0038127580.015
eye developmentGO:00016543230.015
purine nucleotide catabolic processGO:00061951090.015
regulation of cellular component movementGO:0051270420.015
striated muscle cell developmentGO:0055002500.015
positive regulation of cellular catabolic processGO:0031331950.015
glycosyl compound catabolic processGO:19016581120.015
response to organic substanceGO:00100332840.015
regulation of dendrite morphogenesisGO:0048814280.015
positive regulation of nucleotide metabolic processGO:0045981550.015
retina morphogenesis in camera type eyeGO:006004220.015
carboxylic acid metabolic processGO:0019752920.015
tube morphogenesisGO:00352391910.015
cell cell adhesion via plasma membrane adhesion moleculesGO:0098742260.015
mushroom body developmentGO:0016319700.015
cell proliferationGO:00082832990.015
regulation of locomotionGO:0040012420.015
ribonucleoside triphosphate catabolic processGO:00092031080.015
axonal defasciculationGO:0007414120.015
ribonucleoside catabolic processGO:00424541120.015
cellular response to lipopolysaccharideGO:007122230.014
apoptotic processGO:00069151590.014
purine ribonucleoside triphosphate metabolic processGO:00092051190.014
ribonucleoside triphosphate metabolic processGO:00091991190.014
positive regulation of phosphate metabolic processGO:00459371390.014
cellular amino acid metabolic processGO:0006520610.014
molting cycle chitin based cuticleGO:0007591560.014
regulation of cellular catabolic processGO:00313291570.014
regulation of response to woundingGO:1903034190.014
cytoskeleton dependent cytokinesisGO:0061640810.014
negative regulation of epithelial cell proliferationGO:005068040.014
nucleotide metabolic processGO:00091171610.014
single organism biosynthetic processGO:00447112060.014
negative regulation of apoptotic processGO:0043066630.014
positive regulation of phosphorylationGO:0042327870.014
organic substance catabolic processGO:19015753080.014
regulation of mitotic cell cycle phase transitionGO:19019901300.014
embryonic development via the syncytial blastodermGO:00017001480.014
ribose phosphate metabolic processGO:00196931450.014
taxisGO:00423303040.014
signal transduction by phosphorylationGO:00230141070.014
heart processGO:0003015370.014
negative regulation of cellular protein metabolic processGO:0032269850.013
actin cytoskeleton organizationGO:00300362060.013
regulation of cell sizeGO:0008361630.013
memoryGO:0007613940.013
purine containing compound metabolic processGO:00725211550.013
positive regulation of cellular protein metabolic processGO:00322701180.013
regulation of cell divisionGO:0051302720.013
growthGO:00400073590.013
regulation of system processGO:0044057360.013
gastrulationGO:0007369700.013
regulation of intracellular signal transductionGO:19025312360.013
epithelial tube morphogenesisGO:0060562880.013
carbohydrate derivative catabolic processGO:19011361180.013
blastoderm segmentationGO:00073501590.013
positive regulation of cell cycleGO:0045787430.013
regulation of developmental growthGO:00486381740.013
regulation of translationGO:0006417560.013
actin filament based processGO:00300292200.012
cuticle developmentGO:0042335860.012
instar larval developmentGO:0002168550.012
regulation of cell deathGO:00109411730.012
regulation of transcription from rna polymerase ii promoterGO:00063573780.012
intracellular signal transductionGO:00355563000.012
regulation of neurogenesisGO:00507671580.012
regulation of protein phosphorylationGO:0001932640.012
regulation of cell projection organizationGO:0031344920.012
compound eye developmentGO:00487493070.012
nucleoside phosphate metabolic processGO:00067531620.012
regulation of cellular ketone metabolic processGO:001056530.012
regulation of embryonic developmentGO:0045995680.012
photoreceptor cell fate commitmentGO:0046552410.012
regulation of gtp catabolic processGO:0033124440.012
spermatogenesisGO:00072832000.012
response to light stimulusGO:00094161240.012
regulation of phosphorus metabolic processGO:00511742100.012
cellular response to abiotic stimulusGO:0071214580.012
transmembrane transportGO:00550851390.012
positive regulation of rho gtpase activityGO:0032321190.012
axon developmentGO:00615642970.012
regulation of nucleoside metabolic processGO:0009118500.012
heterocycle catabolic processGO:00467001660.011
positive regulation of gtp catabolic processGO:0033126430.011
negative regulation of epidermal growth factor receptor signaling pathwayGO:0042059290.011
larval developmentGO:00021641040.011
regulation of cell morphogenesisGO:00226041630.011
regulation of ras protein signal transductionGO:0046578930.011
regulation of gtpase activityGO:0043087440.011
cell adhesionGO:00071551360.011
positive regulation of catabolic processGO:00098961050.011
regulation of wnt signaling pathwayGO:0030111680.011
inter male aggressive behaviorGO:0002121600.011
cellular response to growth factor stimulusGO:0071363300.011
cellular ketone metabolic processGO:0042180240.011
regulation of erbb signaling pathwayGO:1901184420.011
columnar cuboidal epithelial cell developmentGO:00020662490.011
positive regulation of protein metabolic processGO:00512471280.011
regulation of catabolic processGO:00098941700.011
regulation of cytoskeleton organizationGO:0051493890.011
regulation of establishment of planar polarityGO:0090175220.011
positive regulation of signalingGO:00230562430.011
cellular response to hexose stimulusGO:007133110.011
biological adhesionGO:00226101380.011
potassium ion transportGO:0006813200.011
synaptic growth at neuromuscular junctionGO:00511241190.011
body morphogenesisGO:001017120.011
morphogenesis of embryonic epitheliumGO:0016331940.011
compound eye photoreceptor fate commitmentGO:0001752360.011
muscle fiber developmentGO:0048747120.010
hindgut developmentGO:0061525580.010
chromosome organizationGO:00512763600.010
purine nucleoside triphosphate metabolic processGO:00091441190.010
negative regulation of notch signaling pathwayGO:0045746410.010
digestive system developmentGO:00551231490.010
mitotic cytokinesisGO:0000281500.010
guanosine containing compound metabolic processGO:1901068740.010
exocrine system developmentGO:00352721620.010
single organismal cell cell adhesionGO:0016337450.010
mapk cascadeGO:00001651070.010
kidney developmentGO:000182230.010
deathGO:00162652840.010
guanosine containing compound catabolic processGO:1901069740.010
mrna metabolic processGO:00160711240.010
regulation of mitosisGO:0007088560.010

tow disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.056
inherited metabolic disorderDOID:65500.029
disease of metabolismDOID:001466700.029
nervous system diseaseDOID:86300.024
cardiovascular system diseaseDOID:128700.022
acquired metabolic diseaseDOID:006015800.011