IMP: Integrative Multi-species Prediction

Drosophila melanogaster

155 known processes

CG11376 (Dmel_CG11376)

CG11376 gene product from transcript CG11376-RA

(Aliases: anon-EST:Posey54,Dm zir,Dmel\CG11376)

FLYBASE: FBgn0031216
Entrez: 33165
UniProtKB: Q9VPI9

Process Predictions
Disease Predictions

CG11376 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability	Func Analog Org
encapsulation of foreign target	GO:0035010	38	0.974
immune system process	GO:0002376	347	0.882
melanotic encapsulation of foreign target	GO:0035011	30	0.847
immune effector process	GO:0002252	98	0.643
glycosyl compound catabolic process	GO:1901658	112	0.454
heterocycle catabolic process	GO:0046700	166	0.438
pigment metabolic process	GO:0042440	84	0.418
nucleoside triphosphate catabolic process	GO:0009143	108	0.417
ribonucleoside metabolic process	GO:0009119	127	0.395
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.385
nucleotide catabolic process	GO:0009166	109	0.374
cell adhesion	GO:0007155	136	0.361
appendage development	GO:0048736	401	0.359
ribonucleotide catabolic process	GO:0009261	109	0.339
biological adhesion	GO:0022610	138	0.338
organonitrogen compound catabolic process	GO:1901565	128	0.338
phenol containing compound metabolic process	GO:0018958	57	0.328
cellular catabolic process	GO:0044248	372	0.321
purine nucleotide metabolic process	GO:0006163	146	0.316
purine ribonucleoside catabolic process	GO:0046130	112	0.295
ribose phosphate metabolic process	GO:0019693	145	0.281
nucleoside catabolic process	GO:0009164	112	0.272
cellular protein modification process	GO:0006464	438	0.267
immune response	GO:0006955	246	0.259
nucleobase containing compound catabolic process	GO:0034655	165	0.257
nucleotide metabolic process	GO:0009117	161	0.255
regulation of cell development	GO:0060284	215	0.255	Mouse
appendage morphogenesis	GO:0035107	397	0.254
cellular nitrogen compound catabolic process	GO:0044270	165	0.241
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.232
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.214
protein modification process	GO:0036211	438	0.210
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.209
nucleoside metabolic process	GO:0009116	127	0.192
purine nucleotide catabolic process	GO:0006195	109	0.189
neuron projection guidance	GO:0097485	241	0.189
purine ribonucleoside metabolic process	GO:0046128	127	0.188
purine containing compound catabolic process	GO:0072523	112	0.185
ribonucleotide metabolic process	GO:0009259	145	0.183
purine containing compound metabolic process	GO:0072521	155	0.176
purine nucleoside metabolic process	GO:0042278	127	0.175
nucleoside phosphate metabolic process	GO:0006753	162	0.174
head development	GO:0060322	135	0.171	Mouse
brain development	GO:0007420	120	0.170	Mouse
neurological system process	GO:0050877	358	0.170
ribonucleoside catabolic process	GO:0042454	112	0.169
carbohydrate derivative catabolic process	GO:1901136	118	0.158
organic substance catabolic process	GO:1901575	308	0.157
organelle fission	GO:0048285	340	0.150
regionalization	GO:0003002	416	0.144
nucleobase containing small molecule metabolic process	GO:0055086	174	0.143
axonogenesis	GO:0007409	290	0.142
taxis	GO:0042330	304	0.142
nucleoside phosphate catabolic process	GO:1901292	110	0.130
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.128
cell migration	GO:0016477	238	0.128	Mouse
central nervous system development	GO:0007417	201	0.126	Mouse
regulation of nervous system development	GO:0051960	248	0.121	Mouse
purine ribonucleotide catabolic process	GO:0009154	109	0.120
body morphogenesis	GO:0010171	2	0.117
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.117
negative regulation of gene expression	GO:0010629	387	0.117
glycosyl compound metabolic process	GO:1901657	127	0.116
purine ribonucleotide metabolic process	GO:0009150	145	0.113
catabolic process	GO:0009056	409	0.112
organophosphate metabolic process	GO:0019637	195	0.112
defense response	GO:0006952	300	0.112
nuclear division	GO:0000280	332	0.111
embryo development ending in birth or egg hatching	GO:0009792	152	0.110
chemotaxis	GO:0006935	249	0.110
post embryonic appendage morphogenesis	GO:0035120	385	0.107
nucleoside triphosphate metabolic process	GO:0009141	120	0.106
axon guidance	GO:0007411	233	0.106
regulation of rho protein signal transduction	GO:0035023	20	0.103
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.101
regulation of cell differentiation	GO:0045595	302	0.098	Mouse
wing disc morphogenesis	GO:0007472	344	0.097
imaginal disc derived appendage development	GO:0048737	399	0.094
single organism catabolic process	GO:0044712	228	0.091
axon development	GO:0061564	297	0.088
regulation of anatomical structure morphogenesis	GO:0022603	242	0.088
melanin metabolic process	GO:0006582	47	0.088
small molecule metabolic process	GO:0044281	305	0.086
dendrite development	GO:0016358	204	0.086
camera type eye development	GO:0043010	4	0.082
regulation of cell morphogenesis	GO:0022604	163	0.081
response to organic substance	GO:0010033	284	0.080
mushroom body development	GO:0016319	70	0.078
carbohydrate derivative metabolic process	GO:1901135	217	0.077
organic cyclic compound catabolic process	GO:1901361	168	0.074
cellular macromolecule localization	GO:0070727	220	0.073
cell division	GO:0051301	248	0.073
meiotic nuclear division	GO:0007126	151	0.072
rho protein signal transduction	GO:0007266	14	0.069
positive regulation of molecular function	GO:0044093	136	0.068
morphogenesis of embryonic epithelium	GO:0016331	94	0.066
actin filament organization	GO:0007015	126	0.064
imaginal disc derived wing morphogenesis	GO:0007476	337	0.062
segmentation	GO:0035282	207	0.061
meiotic cell cycle	GO:0051321	171	0.059
negative regulation of cellular metabolic process	GO:0031324	382	0.059
tissue morphogenesis	GO:0048729	297	0.059
meiotic cell cycle process	GO:1903046	132	0.055
negative regulation of response to stimulus	GO:0048585	258	0.054
protein localization	GO:0008104	284	0.054
regulation of cell division	GO:0051302	72	0.054
purine nucleoside catabolic process	GO:0006152	112	0.052
regulation of neurogenesis	GO:0050767	158	0.052	Mouse
actin filament based process	GO:0030029	220	0.051
negative regulation of signal transduction	GO:0009968	206	0.051
regulation of nucleotide catabolic process	GO:0030811	48	0.050
gastrulation	GO:0007369	70	0.050
regulation of cytoskeleton organization	GO:0051493	89	0.049
organonitrogen compound metabolic process	GO:1901564	318	0.047
anterior posterior pattern specification	GO:0009952	136	0.046
guanosine containing compound metabolic process	GO:1901068	74	0.043
establishment or maintenance of cell polarity	GO:0007163	167	0.043
positive regulation of cell communication	GO:0010647	250	0.043
positive regulation of catalytic activity	GO:0043085	118	0.043
growth	GO:0040007	359	0.042
organic hydroxy compound metabolic process	GO:1901615	83	0.042
localization of cell	GO:0051674	257	0.042	Mouse
purine nucleoside monophosphate metabolic process	GO:0009126	50	0.042
regulation of microtubule cytoskeleton organization	GO:0070507	41	0.041
innate immune response	GO:0045087	144	0.040
positive regulation of ras gtpase activity	GO:0032320	36	0.040
cellular amino acid metabolic process	GO:0006520	61	0.040
anatomical structure homeostasis	GO:0060249	97	0.040
regulation of nucleotide metabolic process	GO:0006140	62	0.040
actin cytoskeleton organization	GO:0030036	206	0.039
regulation of organelle organization	GO:0033043	196	0.039
single organismal cell cell adhesion	GO:0016337	45	0.039
tube morphogenesis	GO:0035239	191	0.039
response to radiation	GO:0009314	155	0.038
ovarian follicle cell development	GO:0030707	248	0.038
response to abiotic stimulus	GO:0009628	341	0.037
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.037
melanization defense response	GO:0035006	45	0.037
aromatic compound catabolic process	GO:0019439	166	0.037
single organism behavior	GO:0044708	391	0.037
regulation of immune system process	GO:0002682	176	0.036
cellularization	GO:0007349	90	0.035
dna metabolic process	GO:0006259	227	0.034
positive regulation of developmental process	GO:0051094	143	0.034
regulation of microtubule based process	GO:0032886	49	0.034
organophosphate catabolic process	GO:0046434	112	0.034
hematopoietic or lymphoid organ development	GO:0048534	57	0.033	Mouse
gland morphogenesis	GO:0022612	145	0.033
guanosine containing compound catabolic process	GO:1901069	74	0.033
blastoderm segmentation	GO:0007350	159	0.032
regulation of notch signaling pathway	GO:0008593	100	0.032
intracellular transport	GO:0046907	228	0.032
gtp catabolic process	GO:0006184	72	0.032
embryonic development via the syncytial blastoderm	GO:0001700	148	0.031
meiosis i	GO:0007127	59	0.031
somatic muscle development	GO:0007525	66	0.031
single organism membrane organization	GO:0044802	93	0.030
negative regulation of signaling	GO:0023057	219	0.030
embryonic pattern specification	GO:0009880	174	0.030
positive regulation of signaling	GO:0023056	243	0.030
response to wounding	GO:0009611	94	0.029
regulation of ras gtpase activity	GO:0032318	38	0.029
anterior posterior axis specification	GO:0009948	109	0.029
telencephalon development	GO:0021537	2	0.029
positive regulation of cellular component organization	GO:0051130	156	0.028
negative regulation of developmental process	GO:0051093	201	0.028
dendrite morphogenesis	GO:0048813	199	0.028
regulation of gtpase activity	GO:0043087	44	0.028
single organism cellular localization	GO:1902580	180	0.028
cellular protein localization	GO:0034613	160	0.028
single organism carbohydrate metabolic process	GO:0044723	72	0.028
exocrine system development	GO:0035272	162	0.028
secondary metabolic process	GO:0019748	75	0.027
cell recognition	GO:0008037	102	0.027	Mouse
positive regulation of cell motility	GO:2000147	3	0.027
eggshell chorion assembly	GO:0007306	66	0.027
atp metabolic process	GO:0046034	49	0.026
regulation of cell shape	GO:0008360	113	0.026
hindbrain development	GO:0030902	2	0.026
digestive tract morphogenesis	GO:0048546	127	0.026
purine ribonucleoside monophosphate metabolic process	GO:0009167	50	0.025
regulation of cell cycle	GO:0051726	291	0.025
substrate dependent cell migration	GO:0006929	3	0.025
death	GO:0016265	284	0.025	Mouse
embryonic axis specification	GO:0000578	107	0.024
carboxylic acid metabolic process	GO:0019752	92	0.024
leg disc development	GO:0035218	92	0.024
regulation of molecular function	GO:0065009	217	0.024
regulation of cell death	GO:0010941	173	0.024	Mouse
ameboidal type cell migration	GO:0001667	151	0.024
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.023
positive regulation of proteolysis	GO:0045862	52	0.023
peptidyl amino acid modification	GO:0018193	105	0.023
ribonucleoside monophosphate metabolic process	GO:0009161	51	0.023
negative regulation of biosynthetic process	GO:0009890	277	0.023
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.023
epithelial cell development	GO:0002064	274	0.022
positive regulation of cell differentiation	GO:0045597	64	0.022
protein deglycosylation	GO:0006517	1	0.022
single organism intracellular transport	GO:1902582	207	0.022
maintenance of location	GO:0051235	73	0.022
cell maturation	GO:0048469	144	0.021
regulation of multicellular organismal development	GO:2000026	414	0.021	Mouse
tripartite regional subdivision	GO:0007351	103	0.021
inositol lipid mediated signaling	GO:0048017	4	0.021
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.021
chromosome segregation	GO:0007059	157	0.021
cell cycle phase transition	GO:0044770	140	0.021
endomembrane system organization	GO:0010256	119	0.020
oxoacid metabolic process	GO:0043436	103	0.020
regulation of neuron projection development	GO:0010975	69	0.020
regulation of nucleoside metabolic process	GO:0009118	50	0.020
salivary gland development	GO:0007431	162	0.020
maintenance of protein location in cell	GO:0032507	26	0.020
golgi organization	GO:0007030	66	0.020
morphogenesis of a branching structure	GO:0001763	45	0.020
regulation of cell cycle process	GO:0010564	181	0.019
positive regulation of organelle organization	GO:0010638	65	0.019
homeostatic process	GO:0042592	199	0.019
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.019
positive regulation of purine nucleotide metabolic process	GO:1900544	55	0.019
retina development in camera type eye	GO:0060041	4	0.019
oocyte axis specification	GO:0007309	108	0.019
gland development	GO:0048732	191	0.019
regulation of cell morphogenesis involved in differentiation	GO:0010769	61	0.018
ras protein signal transduction	GO:0007265	88	0.018
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.018
oocyte development	GO:0048599	124	0.018
positive regulation of response to stimulus	GO:0048584	323	0.018
positive regulation of hydrolase activity	GO:0051345	78	0.018
immune system development	GO:0002520	57	0.018	Mouse
purine ribonucleoside monophosphate catabolic process	GO:0009169	38	0.018
negative regulation of rna metabolic process	GO:0051253	251	0.018
regulation of cellular catabolic process	GO:0031329	157	0.018
regulation of neuron differentiation	GO:0045664	103	0.018
n glycan processing	GO:0006491	3	0.018
morphogenesis of an epithelium	GO:0002009	276	0.017
positive regulation of cell projection organization	GO:0031346	29	0.017
regulation of nuclear division	GO:0051783	58	0.017
salivary gland morphogenesis	GO:0007435	145	0.017
regulation of cell projection organization	GO:0031344	92	0.017
carbohydrate metabolic process	GO:0005975	82	0.017
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.017
learning or memory	GO:0007611	141	0.017
regulation of cell proliferation	GO:0042127	163	0.017
positive regulation of signal transduction	GO:0009967	223	0.017
protein polymerization	GO:0051258	42	0.017
regulation of mitotic cell cycle	GO:0007346	190	0.017
positive regulation of cell migration	GO:0030335	2	0.017
regulation of anatomical structure size	GO:0090066	163	0.017
negative regulation of cell differentiation	GO:0045596	143	0.016
negative regulation of cell communication	GO:0010648	223	0.016
neural precursor cell proliferation	GO:0061351	75	0.016	Mouse
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.016
regulation of purine nucleotide catabolic process	GO:0033121	48	0.016
spermatogenesis	GO:0007283	200	0.016
negative regulation of nervous system development	GO:0051961	92	0.016
maintenance of location in cell	GO:0051651	28	0.016
regulation of cellular component biogenesis	GO:0044087	201	0.016
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.016
protein complex biogenesis	GO:0070271	201	0.016
chromosome organization	GO:0051276	360	0.015
imaginal disc derived wing margin morphogenesis	GO:0008587	41	0.015
respiratory system development	GO:0060541	213	0.015
regulation of meiosis	GO:0040020	3	0.015
digestive system development	GO:0055123	149	0.015
wnt signaling pathway	GO:0016055	98	0.015
developmental growth	GO:0048589	280	0.015
ribonucleoside monophosphate catabolic process	GO:0009158	39	0.015
cellular ketone metabolic process	GO:0042180	24	0.015
regulation of cellular ketone metabolic process	GO:0010565	3	0.015
regulation of synapse structure and activity	GO:0050803	128	0.015
synaptic transmission	GO:0007268	288	0.015
cell motility	GO:0048870	251	0.015	Mouse
positive regulation of nervous system development	GO:0051962	69	0.015
response to light stimulus	GO:0009416	124	0.015
locomotory behavior	GO:0007626	176	0.015
regulation of transport	GO:0051049	181	0.014
regulation of cellular protein metabolic process	GO:0032268	243	0.014
cell junction organization	GO:0034330	57	0.014
regulation of protein complex assembly	GO:0043254	42	0.014
regulation of localization	GO:0032879	275	0.014
stem cell differentiation	GO:0048863	117	0.014
rna localization	GO:0006403	115	0.014
modification dependent protein catabolic process	GO:0019941	78	0.014
stem cell development	GO:0048864	79	0.014
embryonic morphogenesis	GO:0048598	206	0.014
digestive tract development	GO:0048565	149	0.014
mitochondrial membrane organization	GO:0007006	3	0.014
intracellular protein transport	GO:0006886	104	0.013
protein modification by small protein conjugation	GO:0032446	79	0.013
response to organic cyclic compound	GO:0014070	89	0.013
circadian rhythm	GO:0007623	105	0.013
nucleoside monophosphate metabolic process	GO:0009123	52	0.013
positive regulation of gtp catabolic process	GO:0033126	43	0.013
chemosensory behavior	GO:0007635	106	0.013
mesoderm development	GO:0007498	78	0.013
purine nucleoside monophosphate catabolic process	GO:0009128	38	0.013
cytokinesis	GO:0000910	90	0.013
establishment of protein localization	GO:0045184	163	0.013
cell proliferation	GO:0008283	299	0.013	Mouse
lateral inhibition	GO:0046331	206	0.013
cellular response to dna damage stimulus	GO:0006974	223	0.013
neuron recognition	GO:0008038	101	0.013
regulation of proteolysis	GO:0030162	87	0.013
vesicle mediated transport	GO:0016192	381	0.013
detection of stimulus	GO:0051606	156	0.013
chaeta development	GO:0022416	97	0.013
plasma membrane organization	GO:0007009	26	0.012
camera type eye morphogenesis	GO:0048593	2	0.012
notch signaling pathway	GO:0007219	120	0.012
multi organism reproductive behavior	GO:0044705	121	0.012
macromolecular complex assembly	GO:0065003	256	0.012
actomyosin structure organization	GO:0031032	56	0.012
anterior posterior axis specification embryo	GO:0008595	103	0.012
female meiotic division	GO:0007143	70	0.012
adult locomotory behavior	GO:0008344	76	0.012
positive regulation of cellular biosynthetic process	GO:0031328	316	0.012
negative regulation of cellular biosynthetic process	GO:0031327	277	0.012
cellular macromolecule catabolic process	GO:0044265	136	0.012
protein modification by small protein conjugation or removal	GO:0070647	106	0.012
protein transport	GO:0015031	155	0.012
small gtpase mediated signal transduction	GO:0007264	88	0.012
proteolysis	GO:0006508	192	0.012
protein phosphorylation	GO:0006468	169	0.012
forebrain development	GO:0030900	2	0.012	Mouse
regulation of embryonic cell shape	GO:0016476	30	0.012
regulation of intracellular signal transduction	GO:1902531	236	0.012
regulation of purine nucleotide metabolic process	GO:1900542	62	0.012
single organism cell adhesion	GO:0098602	47	0.012
regulation of catabolic process	GO:0009894	170	0.012
regulation of catalytic activity	GO:0050790	185	0.012
axis specification	GO:0009798	167	0.011
hemopoiesis	GO:0030097	46	0.011	Mouse
regulation of ras protein signal transduction	GO:0046578	93	0.011
regulation of cellular localization	GO:0060341	136	0.011
heart development	GO:0007507	82	0.011
regulation of cell cycle phase transition	GO:1901987	130	0.011
nitric oxide metabolic process	GO:0046209	1	0.011
gtp metabolic process	GO:0046039	72	0.011
synapse organization	GO:0050808	196	0.011
negative regulation of programmed cell death	GO:0043069	72	0.011	Mouse
single organism biosynthetic process	GO:0044711	206	0.011
microtubule cytoskeleton organization involved in mitosis	GO:1902850	52	0.011
endocytosis	GO:0006897	310	0.011
regulation of intracellular transport	GO:0032386	64	0.011
posttranscriptional regulation of gene expression	GO:0010608	145	0.011
multi multicellular organism process	GO:0044706	123	0.011
regulation of dendrite development	GO:0050773	37	0.010
adult behavior	GO:0030534	137	0.010
multi organism behavior	GO:0051705	175	0.010
retina morphogenesis in camera type eye	GO:0060042	2	0.010
positive regulation of cellular component biogenesis	GO:0044089	80	0.010
organelle fusion	GO:0048284	46	0.010
regulation of axonogenesis	GO:0050770	32	0.010
regulation of actin filament based process	GO:0032970	42	0.010
response to reactive oxygen species	GO:0000302	24	0.010
regulation of hydrolase activity	GO:0051336	97	0.010

CG11376 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	nervous system disease	DOID:863	0	0.030
	disease of anatomical entity	DOID:7	0	0.030

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