Drosophila melanogaster

37 known processes

Trx-2 (Dmel_CG31884)

thioredoxin-2

(Aliases: dmtrx-2,DmelTrx-2,Dmel\CG31884,anon-WO0118547.188,31884,DmTrx-2,CG31884,CG3864)

Trx-2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to oxidative stressGO:0006979860.998
response to oxygen radicalGO:000030530.940
cellular response to oxidative stressGO:0034599280.833
immune responseGO:00069552460.778
response to abiotic stimulusGO:00096283410.756
negative regulation of cellular metabolic processGO:00313243820.694
response to reactive oxygen speciesGO:0000302240.673
cellular response to reactive oxygen speciesGO:0034614140.651
immune system processGO:00023763470.636
defense response to other organismGO:00985422250.620
response to oxygen containing compoundGO:19017002000.611
response to bacteriumGO:00096171980.611
organonitrogen compound metabolic processGO:19015643180.593
intracellular signal transductionGO:00355563000.560
response to external biotic stimulusGO:00432072930.555
regulation of immune system processGO:00026821760.512
peptide metabolic processGO:0006518800.502
single organism behaviorGO:00447083910.459
regulation of immune responseGO:00507761180.457
response to endogenous stimulusGO:00097191190.457
defense responseGO:00069523000.405
regulation of cell deathGO:00109411730.398
catabolic processGO:00090564090.393
response to biotic stimulusGO:00096072940.391
determination of adult lifespanGO:00083401370.370
negative regulation of nitrogen compound metabolic processGO:00511722650.367
regulation of response to stressGO:00801342000.354
negative regulation of rna metabolic processGO:00512532510.342
positive regulation of response to stimulusGO:00485843230.335
regulation of multi organism processGO:00439001310.332
response to superoxideGO:000030330.330
deathGO:00162652840.322
carboxylic acid metabolic processGO:0019752920.315
negative regulation of response to stimulusGO:00485852580.310
response to other organismGO:00517072930.305
regulation of transcription from rna polymerase ii promoterGO:00063573780.302
hydrogen peroxide catabolic processGO:004274460.300
negative regulation of rna biosynthetic processGO:19026792400.289
transcription from rna polymerase ii promoterGO:00063663680.286
cellular response to extracellular stimulusGO:0031668640.285
response to organic substanceGO:00100332840.281
negative regulation of nucleobase containing compound metabolic processGO:00459342610.269
regulation of response to external stimulusGO:00321011150.269
small molecule metabolic processGO:00442813050.268
cell deathGO:00082192790.268
defense response to bacteriumGO:00427421780.249
negative regulation of transcription dna templatedGO:00458922370.246
cellular amide metabolic processGO:0043603800.246
regulation of defense responseGO:00313471020.245
response to temperature stimulusGO:00092661060.240
negative regulation of nucleic acid templated transcriptionGO:19035072400.231
cellular response to oxygen containing compoundGO:1901701790.228
programmed cell deathGO:00125012570.218
pigment metabolic processGO:0042440840.215
cell proliferationGO:00082832990.212
positive regulation of intracellular signal transductionGO:19025331160.210
response to extracellular stimulusGO:00099911160.208
agingGO:00075681430.207
innate immune responseGO:00450871440.191
response to heatGO:0009408630.182
cellular amino acid metabolic processGO:0006520610.174
central nervous system developmentGO:00074172010.165
paracrine signalingGO:003800170.164
cellular protein modification processGO:00064644380.163
reactive oxygen species metabolic processGO:0072593220.162
response to hydrogen peroxideGO:0042542110.161
response to radiationGO:00093141550.158
regulation of multicellular organismal developmentGO:20000264140.155
positive regulation of macromolecule biosynthetic processGO:00105572830.150
establishment of localization in cellGO:00516494020.150
regulation of phosphorylationGO:00423251470.147
positive regulation of nitrogen compound metabolic processGO:00511733540.143
gland developmentGO:00487321910.142
appendage developmentGO:00487364010.138
amine metabolic processGO:0009308120.136
positive regulation of cell communicationGO:00106472500.133
endocytosisGO:00068973100.131
regulation of cell proliferationGO:00421271630.131
aromatic compound catabolic processGO:00194391660.129
regulation of response to biotic stimulusGO:0002831630.122
regulation of molecular functionGO:00650092170.121
cellular response to chemical stimulusGO:00708871990.120
nuclear dna replicationGO:003326010.120
regulation of intracellular signal transductionGO:19025312360.119
regulation of protein metabolic processGO:00512462560.117
response to axon injuryGO:0048678120.116
positive regulation of signal transductionGO:00099672230.115
pigmentationGO:0043473750.113
intrinsic apoptotic signaling pathwayGO:0097193160.113
developmental growthGO:00485892800.109
behavioral response to ethanolGO:0048149490.106
regulation of anatomical structure sizeGO:00900661630.103
negative regulation of cell communicationGO:00106482230.102
response to metal ionGO:0010038230.102
regulation of apoptotic processGO:00429811300.100
regulation of anatomical structure morphogenesisGO:00226032420.098
phosphorylationGO:00163102940.095
intracellular transportGO:00469072280.095
immune response activating signal transductionGO:000275720.094
homeostatic processGO:00425921990.093
positive regulation of biosynthetic processGO:00098913160.093
apoptotic signaling pathwayGO:0097190270.092
positive regulation of cellular biosynthetic processGO:00313283160.091
regulation of cellular protein metabolic processGO:00322682430.091
negative regulation of biosynthetic processGO:00098902770.091
developmental pigmentationGO:0048066680.088
cellular nitrogen compound catabolic processGO:00442701650.088
cellular response to endogenous stimulusGO:0071495800.087
positive regulation of signalingGO:00230562430.086
taxisGO:00423303040.086
negative regulation of macromolecule biosynthetic processGO:00105582700.086
regulation of catabolic processGO:00098941700.085
negative regulation of defense responseGO:0031348350.085
cellular response to dna damage stimulusGO:00069742230.085
cellular response to nutrient levelsGO:0031669620.084
rna processingGO:00063961470.084
negative regulation of gene expressionGO:00106293870.083
response to inorganic substanceGO:0010035440.082
single organism biosynthetic processGO:00447112060.082
brain developmentGO:00074201200.081
negative regulation of signal transductionGO:00099682060.080
regulation of cell differentiationGO:00455953020.077
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.075
muscle structure developmentGO:00610612240.074
response to nutrient levelsGO:00316671140.074
cellular modified amino acid metabolic processGO:0006575450.073
vesicle mediated transportGO:00161923810.070
head developmentGO:00603221350.070
Fly
carbohydrate derivative metabolic processGO:19011352170.069
single organism intracellular transportGO:19025822070.069
cell adhesionGO:00071551360.069
negative regulation of molecular functionGO:0044092510.065
regulation of mapk cascadeGO:0043408920.065
regulation of cellular response to stressGO:0080135890.065
phagocytosisGO:00069092150.063
organonitrogen compound biosynthetic processGO:19015661170.063
negative regulation of signalingGO:00230572190.063
oxoacid metabolic processGO:00434361030.062
regulation of developmental growthGO:00486381740.062
nucleoside catabolic processGO:00091641120.061
cellular response to organic substanceGO:00713101320.060
cellular response to external stimulusGO:0071496660.060
regulation of cellular amine metabolic processGO:003323830.060
organic acid metabolic processGO:00060821030.059
regulation of programmed cell deathGO:00430671520.058
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.057
developmental programmed cell deathGO:00106231380.057
defense response to gram negative bacteriumGO:0050829940.057
humoral immune responseGO:00069591170.057
growthGO:00400073590.056
biological adhesionGO:00226101380.056
cytoplasmic transportGO:00164821300.056
organophosphate metabolic processGO:00196371950.055
tissue deathGO:00162711020.054
signal transduction by phosphorylationGO:00230141070.053
single organism catabolic processGO:00447122280.052
negative regulation of protein metabolic processGO:0051248850.051
enzyme linked receptor protein signaling pathwayGO:00071671790.051
epidermal cell differentiationGO:0009913510.051
response to starvationGO:0042594970.050
neurological system processGO:00508773580.050
positive regulation of gene expressionGO:00106282900.050
glycosyl compound metabolic processGO:19016571270.049
protein phosphorylationGO:00064681690.049
exocrine system developmentGO:00352721620.048
cellular amine metabolic processGO:0044106120.048
regulation of antimicrobial peptide productionGO:0002784440.048
regulation of autophagyGO:0010506620.046
positive regulation of immune system processGO:0002684680.045
positive regulation of rna biosynthetic processGO:19026802660.045
negative regulation of multicellular organismal processGO:00512411420.044
negative regulation of programmed cell deathGO:0043069720.044
negative regulation of cell deathGO:0060548810.044
carbohydrate metabolic processGO:0005975820.044
activation of innate immune responseGO:000221840.043
nucleotide metabolic processGO:00091171610.043
response to woundingGO:0009611940.043
organonitrogen compound catabolic processGO:19015651280.042
positive regulation of protein metabolic processGO:00512471280.042
imaginal disc derived appendage morphogenesisGO:00351143950.042
cellular response to hydrogen peroxideGO:007030170.041
protein localizationGO:00081042840.041
purine containing compound metabolic processGO:00725211550.041
maintenance of locationGO:0051235730.040
negative regulation of cellular biosynthetic processGO:00313272770.040
regulation of phosphate metabolic processGO:00192202100.039
response to cadmium ionGO:004668690.039
cellular catabolic processGO:00442483720.039
nucleotide catabolic processGO:00091661090.039
regulation of catalytic activityGO:00507901850.038
regulation of antimicrobial humoral responseGO:0002759500.038
mapk cascadeGO:00001651070.038
organic substance transportGO:00717022570.037
nucleocytoplasmic transportGO:0006913720.037
regulation of phosphorus metabolic processGO:00511742100.037
multicellular organismal agingGO:00102591400.036
purine containing compound catabolic processGO:00725231120.036
regulation of humoral immune responseGO:0002920510.036
regulation of protein modification processGO:00313991120.036
negative regulation of apoptotic processGO:0043066630.035
positive regulation of immune responseGO:0050778630.034
positive regulation of macromolecule metabolic processGO:00106044050.033
positive regulation of innate immune responseGO:0045089380.033
response to light stimulusGO:00094161240.032
regulation of multicellular organism growthGO:0040014400.032
negative regulation of catalytic activityGO:0043086420.032
multicellular organism growthGO:0035264460.031
protein complex assemblyGO:00064612000.031
embryonic development via the syncytial blastodermGO:00017001480.031
immune response regulating signaling pathwayGO:000276420.031
localization of cellGO:00516742570.031
positive regulation of cell migrationGO:003033520.030
muscle organ developmentGO:00075171270.030
glutathione metabolic processGO:0006749370.030
nucleoside phosphate catabolic processGO:19012921100.030
response to organonitrogen compoundGO:0010243750.030
purine ribonucleotide catabolic processGO:00091541090.029
regulation of protein stabilityGO:0031647430.029
protein modification processGO:00362114380.029
cell agingGO:000756920.029
oocyte developmentGO:00485991240.029
response to ethanolGO:0045471590.029
histolysisGO:00075591020.028
gland morphogenesisGO:00226121450.028
organic substance catabolic processGO:19015753080.028
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.028
establishment of protein localization to organelleGO:0072594620.027
apoptotic processGO:00069151590.027
regulation of hydrolase activityGO:0051336970.027
positive regulation of multicellular organismal processGO:00512401430.026
nucleobase containing small molecule metabolic processGO:00550861740.026
regulation of protein phosphorylationGO:0001932640.026
cellular response to starvationGO:0009267610.026
regulation of cell morphogenesisGO:00226041630.026
anatomical structure homeostasisGO:0060249970.026
regulation of cell developmentGO:00602842150.025
response to alcoholGO:0097305950.025
positive regulation of defense responseGO:0031349590.025
positive regulation of transcription dna templatedGO:00458932660.025
regulation of cellular response to oxidative stressGO:190040740.025
cellular homeostasisGO:0019725800.024
cellular response to metal ionGO:007124860.024
positive regulation of developmental processGO:00510941430.024
purine ribonucleotide metabolic processGO:00091501450.024
positive regulation of mapk cascadeGO:0043410630.024
innate immune response activating signal transductionGO:000275820.024
protein targetingGO:0006605640.024
organic cyclic compound catabolic processGO:19013611680.023
ameboidal type cell migrationGO:00016671510.023
regulation of cellular ketone metabolic processGO:001056530.023
regulation of innate immune responseGO:0045088710.023
covalent chromatin modificationGO:00165691060.022
response to fungusGO:0009620500.022
salivary gland histolysisGO:0035070880.022
regulation of terminal button organizationGO:2000331110.022
positive regulation of response to external stimulusGO:0032103440.022
cellular response to cadmium ionGO:007127660.022
purine nucleotide metabolic processGO:00061631460.022
purine nucleotide catabolic processGO:00061951090.021
single organism cellular localizationGO:19025801800.021
regulation of transferase activityGO:0051338580.021
nuclear transportGO:0051169720.021
nucleoside phosphate metabolic processGO:00067531620.020
response to coldGO:0009409130.020
salivary gland morphogenesisGO:00074351450.020
cognitionGO:00508901410.020
dephosphorylationGO:0016311510.020
chemotaxisGO:00069352490.020
purine ribonucleoside triphosphate metabolic processGO:00092051190.019
positive regulation of nucleobase containing compound metabolic processGO:00459353320.019
regulation of protein kinase activityGO:0045859510.019
negative regulation of developmental processGO:00510932010.019
heterocycle catabolic processGO:00467001660.019
tissue morphogenesisGO:00487292970.019
regulation of cellular catabolic processGO:00313291570.019
lipid metabolic processGO:00066291210.018
regulation of cytoplasmic transportGO:1903649470.018
response to nitrogen compoundGO:1901698900.018
cellular macromolecule localizationGO:00707272200.018
regulation of nervous system developmentGO:00519602480.018
intracellular protein transportGO:00068861040.018
positive regulation of cell sizeGO:0045793210.018
negative regulation of cell differentiationGO:00455961430.018
chromatin organizationGO:00063252070.018
salivary gland cell autophagic cell deathGO:0035071830.017
positive regulation of nucleic acid templated transcriptionGO:19035082660.017
stress activated protein kinase signaling cascadeGO:0031098550.017
cation transportGO:00068121100.017
positive regulation of cellular protein metabolic processGO:00322701180.017
skin developmentGO:0043588650.017
post embryonic appendage morphogenesisGO:00351203850.017
appendage morphogenesisGO:00351073970.017
response to lipopolysaccharideGO:003249640.016
sprouting of injured axonGO:004868230.016
muscle tissue morphogenesisGO:006041520.016
ribonucleotide metabolic processGO:00092591450.016
actin cytoskeleton organizationGO:00300362060.016
positive regulation of cell proliferationGO:0008284470.016
immune system developmentGO:0002520570.016
positive regulation of cell motilityGO:200014730.016
establishment or maintenance of cell polarityGO:00071631670.016
negative regulation of cellular component organizationGO:00511291080.016
peptidyl amino acid modificationGO:00181931050.016
actin filament based processGO:00300292200.015
cellular ketone metabolic processGO:0042180240.015
positive regulation of phosphorus metabolic processGO:00105621390.015
ribonucleotide catabolic processGO:00092611090.015
positive regulation of rna metabolic processGO:00512542710.015
macromolecule catabolic processGO:00090571610.015
protein transportGO:00150311550.015
secondary metabolic processGO:0019748750.015
regulation of behaviorGO:0050795750.015
positive regulation of catalytic activityGO:00430851180.015
cellular response to organonitrogen compoundGO:0071417360.015
salivary gland developmentGO:00074311620.015
negative regulation of immune system processGO:0002683500.015
release of sequestered calcium ion into cytosolGO:005120910.014
cell motilityGO:00488702510.014
divalent metal ion transportGO:0070838260.014
regulation of cellular localizationGO:00603411360.014
organic hydroxy compound metabolic processGO:1901615830.014
single organism carbohydrate metabolic processGO:0044723720.014
striated muscle cell differentiationGO:0051146900.014
negative regulation of sequestering of calcium ionGO:005128320.014
eye developmentGO:00016543230.014
defense response to fungusGO:0050832480.014
establishment of protein localizationGO:00451841630.014
long term memoryGO:0007616620.014
protein targeting to nucleusGO:0044744510.014
autophagic cell deathGO:0048102830.014
carbohydrate derivative catabolic processGO:19011361180.014
positive regulation of apoptotic signaling pathwayGO:200123540.014
cell migrationGO:00164772380.013
positive regulation of defense response to bacteriumGO:1900426230.013
purine ribonucleoside metabolic processGO:00461281270.013
cellular protein localizationGO:00346131600.013
negative regulation of intracellular signal transductionGO:1902532570.013
regulation of cellular amino acid metabolic processGO:000652100.013
developmental maturationGO:00217001720.013
organ or tissue specific immune responseGO:0002251100.013
regulation of sequestering of calcium ionGO:005128230.013
posttranscriptional regulation of gene expressionGO:00106081450.013
protein complex biogenesisGO:00702712010.013
muscle tissue developmentGO:0060537300.013
cytosolic calcium ion transportGO:006040120.013
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.012
regulation of adult chitin containing cuticle pigmentationGO:0048082130.012
regulation of small gtpase mediated signal transductionGO:0051056930.012
nucleobase containing compound catabolic processGO:00346551650.012
single organism cell adhesionGO:0098602470.012
sensory perceptionGO:00076001960.012
antimicrobial humoral responseGO:0019730990.012
hematopoietic or lymphoid organ developmentGO:0048534570.012
regulation of dna templated transcription in response to stressGO:004362040.012
chemical homeostasisGO:0048878920.011
cellular protein complex assemblyGO:0043623710.011
regulation of neurogenesisGO:00507671580.011
heart morphogenesisGO:0003007320.011
embryo development ending in birth or egg hatchingGO:00097921520.011
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.011
positive regulation of reactive oxygen species metabolic processGO:200037900.011
response to water deprivationGO:000941440.011
ribose phosphate metabolic processGO:00196931450.011
left right axis specificationGO:007098610.011
cellular response to hormone stimulusGO:0032870440.011
cell type specific apoptotic processGO:0097285380.011
methylationGO:0032259470.011
negative regulation of protein phosphorylationGO:0001933170.011
stress activated mapk cascadeGO:0051403520.011
positive regulation of nuclear divisionGO:0051785140.011
epithelial cell differentiationGO:00308553220.010
positive regulation of apoptotic processGO:0043065470.010
regulation of jnk cascadeGO:0046328400.010
regulation of proteolysisGO:0030162870.010
intracellular receptor signaling pathwayGO:0030522190.010
cell cycle checkpointGO:0000075950.010
protein localization to organelleGO:0033365820.010
positive regulation of phosphorylationGO:0042327870.010
cell activationGO:000177590.010
response to organic cyclic compoundGO:0014070890.010
response to hormoneGO:0009725450.010
negative regulation of innate immune responseGO:0045824300.010
cellular response to inorganic substanceGO:007124180.010
wing disc morphogenesisGO:00074723440.010

Trx-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.090
disease of cellular proliferationDOID:1456600.011