Drosophila melanogaster

110 known processes

GABA-B-R1 (Dmel_CG15274)

metabotropic GABA-B receptor subtype 1

(Aliases: D-GABA[[B]]R1,BG:DS00929.6,Dmel\CG15274,anon-WO0170980.176,anon-WO0170980.175,CG15274,GB1,GABA[[B]],GABA[[B]]R1,D-Gaba1)

GABA-B-R1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
single organism behaviorGO:00447083910.098
eye morphogenesisGO:00485922600.080
regulation of multicellular organismal developmentGO:20000264140.073
eye developmentGO:00016543230.070
neurological system processGO:00508773580.069
cell cell signaling involved in cell fate commitmentGO:00451682100.057
lateral inhibitionGO:00463312060.055
sensory organ morphogenesisGO:00905962600.053
g protein coupled receptor signaling pathwayGO:00071861360.050
compound eye developmentGO:00487493070.048
protein modification processGO:00362114380.047
cellular protein modification processGO:00064644380.047
positive regulation of macromolecule metabolic processGO:00106044050.044
deathGO:00162652840.043
positive regulation of nucleobase containing compound metabolic processGO:00459353320.042
organelle assemblyGO:00709251980.042
intracellular signal transductionGO:00355563000.042
phosphorylationGO:00163102940.040
sensory perceptionGO:00076001960.038
positive regulation of biosynthetic processGO:00098913160.037
regulation of molecular functionGO:00650092170.037
adult behaviorGO:00305341370.037
organonitrogen compound metabolic processGO:19015643180.036
positive regulation of cellular biosynthetic processGO:00313283160.036
positive regulation of response to stimulusGO:00485843230.035
compound eye morphogenesisGO:00017452490.035
regulation of cell deathGO:00109411730.034
regulation of intracellular signal transductionGO:19025312360.034
positive regulation of nitrogen compound metabolic processGO:00511733540.033
transcription from rna polymerase ii promoterGO:00063663680.033
response to organic substanceGO:00100332840.033
enzyme linked receptor protein signaling pathwayGO:00071671790.033
regulation of nervous system developmentGO:00519602480.033
programmed cell deathGO:00125012570.032
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.032
appendage morphogenesisGO:00351073970.032
locomotory behaviorGO:00076261760.032
regulation of transcription from rna polymerase ii promoterGO:00063573780.032
growthGO:00400073590.032
cell deathGO:00082192790.032
positive regulation of rna metabolic processGO:00512542710.031
regulation of phosphorus metabolic processGO:00511742100.031
positive regulation of phosphate metabolic processGO:00459371390.031
regulation of cellular protein metabolic processGO:00322682430.031
positive regulation of nucleic acid templated transcriptionGO:19035082660.031
negative regulation of cell communicationGO:00106482230.030
negative regulation of signal transductionGO:00099682060.030
neuron projection guidanceGO:00974852410.030
appendage developmentGO:00487364010.030
positive regulation of signalingGO:00230562430.030
vesicle mediated transportGO:00161923810.029
negative regulation of cellular metabolic processGO:00313243820.029
forebrain developmentGO:003090020.029
negative regulation of signalingGO:00230572190.029
protein phosphorylationGO:00064681690.029
taxisGO:00423303040.028
regionalizationGO:00030024160.028
small molecule metabolic processGO:00442813050.028
compound eye photoreceptor cell differentiationGO:00017511400.028
positive regulation of cell communicationGO:00106472500.028
regulation of phosphate metabolic processGO:00192202100.028
negative regulation of response to stimulusGO:00485852580.027
regulation of cellular component biogenesisGO:00440872010.027
eye photoreceptor cell differentiationGO:00017541450.027
wing disc morphogenesisGO:00074723440.027
catabolic processGO:00090564090.027
photoreceptor cell differentiationGO:00465301700.027
cellular amino acid metabolic processGO:0006520610.027
imaginal disc derived wing morphogenesisGO:00074763370.027
cellular catabolic processGO:00442483720.026
regulation of cell cycleGO:00517262910.026
apoptotic processGO:00069151590.026
ras protein signal transductionGO:0007265880.026
positive regulation of rna biosynthetic processGO:19026802660.026
endocytosisGO:00068973100.026
organic acid metabolic processGO:00060821030.026
positive regulation of multicellular organismal processGO:00512401430.026
negative regulation of nitrogen compound metabolic processGO:00511722650.025
regulation of phosphorylationGO:00423251470.025
positive regulation of gene expressionGO:00106282900.025
photoreceptor cell developmentGO:0042461960.025
eye photoreceptor cell developmentGO:0042462810.025
positive regulation of signal transductionGO:00099672230.025
regulation of catalytic activityGO:00507901850.025
organic substance catabolic processGO:19015753080.025
positive regulation of macromolecule biosynthetic processGO:00105572830.024
chromosome organizationGO:00512763600.024
positive regulation of transcription dna templatedGO:00458932660.024
regulation of cell proliferationGO:00421271630.024
protein localizationGO:00081042840.024
cognitionGO:00508901410.024
phagocytosisGO:00069092150.024
positive regulation of phosphorus metabolic processGO:00105621390.023
regulation of cell differentiationGO:00455953020.023
cell proliferationGO:00082832990.023
regulation of protein metabolic processGO:00512462560.023
proteolysisGO:00065081920.023
spindle organizationGO:00070512530.023
cellular component assembly involved in morphogenesisGO:00109271510.023
kidney developmentGO:000182230.023
carboxylic acid metabolic processGO:0019752920.023
axon developmentGO:00615642970.022
post embryonic appendage morphogenesisGO:00351203850.022
imaginal disc derived appendage developmentGO:00487373990.022
imaginal disc derived appendage morphogenesisGO:00351143950.022
regulation of localizationGO:00328792750.022
chemotaxisGO:00069352490.022
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.022
cellular amine metabolic processGO:0044106120.022
negative regulation of gene expressionGO:00106293870.021
sensory perception of smellGO:0007608800.021
response to oxygen containing compoundGO:19017002000.021
oxoacid metabolic processGO:00434361030.021
mrna metabolic processGO:00160711240.021
nuclear divisionGO:00002803320.021
cellular response to chemical stimulusGO:00708871990.020
multi multicellular organism processGO:00447061230.020
response to light stimulusGO:00094161240.020
segmentationGO:00352822070.020
regulation of mapk cascadeGO:0043408920.020
developmental maturationGO:00217001720.020
compound eye photoreceptor developmentGO:0042051780.020
small gtpase mediated signal transductionGO:0007264880.020
cell divisionGO:00513012480.020
rna splicingGO:0008380830.020
rna processingGO:00063961470.020
neuromuscular junction developmentGO:00075281490.020
carbohydrate derivative metabolic processGO:19011352170.020
nucleobase containing compound catabolic processGO:00346551650.019
nucleobase containing small molecule metabolic processGO:00550861740.019
macromolecular complex assemblyGO:00650032560.019
purine ribonucleotide metabolic processGO:00091501450.019
negative regulation of cellular biosynthetic processGO:00313272770.019
negative regulation of rna biosynthetic processGO:19026792400.019
endomembrane system organizationGO:00102561190.019
developmental growthGO:00485892800.019
sleepGO:0030431490.019
positive regulation of molecular functionGO:00440931360.019
positive regulation of catalytic activityGO:00430851180.019
store operated calcium entryGO:000211530.019
negative regulation of rna metabolic processGO:00512532510.019
cellular modified amino acid metabolic processGO:0006575450.019
anterior posterior pattern specificationGO:00099521360.018
regulation of synapse assemblyGO:0051963940.018
organophosphate metabolic processGO:00196371950.018
response to radiationGO:00093141550.018
neuropeptide signaling pathwayGO:0007218450.018
regulation of apoptotic processGO:00429811300.018
cell projection assemblyGO:0030031940.018
regulation of cellular ketone metabolic processGO:001056530.018
neuron recognitionGO:00080381010.018
negative regulation of biosynthetic processGO:00098902770.018
body morphogenesisGO:001017120.018
aromatic compound catabolic processGO:00194391660.018
muscle structure developmentGO:00610612240.018
anatomical structure homeostasisGO:0060249970.018
response to abiotic stimulusGO:00096283410.018
actin cytoskeleton organizationGO:00300362060.018
regulation of synaptic growth at neuromuscular junctionGO:0008582890.018
regulation of anatomical structure morphogenesisGO:00226032420.018
connective tissue developmentGO:006144830.018
synaptic growth at neuromuscular junctionGO:00511241190.018
cellular homeostasisGO:0019725800.018
cellular macromolecule localizationGO:00707272200.018
single organism catabolic processGO:00447122280.018
adult locomotory behaviorGO:0008344760.018
organic cyclic compound catabolic processGO:19013611680.018
regulation of programmed cell deathGO:00430671520.017
learning or memoryGO:00076111410.017
organelle fissionGO:00482853400.017
multi organism behaviorGO:00517051750.017
regulation of cellular catabolic processGO:00313291570.017
negative regulation of nucleobase containing compound metabolic processGO:00459342610.017
regulation of developmental growthGO:00486381740.017
response to monosaccharideGO:003428440.017
rhythmic processGO:00485111060.017
mitotic spindle organizationGO:00070522200.017
regulation of small gtpase mediated signal transductionGO:0051056930.017
regulation of cellular amino acid metabolic processGO:000652100.017
purine ribonucleoside metabolic processGO:00461281270.017
mapk cascadeGO:00001651070.017
localization of cellGO:00516742570.017
response to endogenous stimulusGO:00097191190.016
nucleoside catabolic processGO:00091641120.016
cell recognitionGO:00080371020.016
axis specificationGO:00097981670.016
cilium assemblyGO:0042384380.016
rhabdomere developmentGO:0042052380.016
positive regulation of developmental processGO:00510941430.016
protein complex biogenesisGO:00702712010.016
head developmentGO:00603221350.016
positive regulation of protein metabolic processGO:00512471280.016
regulation of growthGO:00400082330.016
response to lipopolysaccharideGO:003249640.016
positive regulation of phosphorylationGO:0042327870.016
positive regulation of intracellular signal transductionGO:19025331160.016
establishment of localization in cellGO:00516494020.016
sulfur compound metabolic processGO:0006790590.016
muscle organ developmentGO:00075171270.016
salivary gland developmentGO:00074311620.016
actin filament based processGO:00300292200.016
axonogenesisGO:00074092900.016
organic substance transportGO:00717022570.016
amine metabolic processGO:0009308120.016
regulation of response to stressGO:00801342000.016
embryonic pattern specificationGO:00098801740.016
regulation of mitotic cell cycleGO:00073461900.016
single organism intracellular transportGO:19025822070.016
axon guidanceGO:00074112330.016
negative regulation of multicellular organismal processGO:00512411420.016
detection of chemical stimulusGO:0009593930.015
blastoderm segmentationGO:00073501590.015
signal transduction by phosphorylationGO:00230141070.015
response to organic cyclic compoundGO:0014070890.015
regulation of ras protein signal transductionGO:0046578930.015
purine containing compound metabolic processGO:00725211550.015
nucleoside phosphate metabolic processGO:00067531620.015
regulation of cellular amine metabolic processGO:003323830.015
cell motilityGO:00488702510.015
regulation of cell developmentGO:00602842150.015
synapse assemblyGO:00074161430.015
camera type eye developmentGO:004301040.015
regulation of catabolic processGO:00098941700.015
regulation of anatomical structure sizeGO:00900661630.015
detection of chemical stimulus involved in sensory perceptionGO:0050907750.015
morphogenesis of an epitheliumGO:00020092760.015
reproductive behaviorGO:00190981220.015
single organism biosynthetic processGO:00447112060.015
circadian behaviorGO:0048512760.015
regulation of alternative mrna splicing via spliceosomeGO:0000381600.015
negative regulation of transcription dna templatedGO:00458922370.015
telencephalon developmentGO:002153720.015
cell cell adhesion via plasma membrane adhesion moleculesGO:0098742260.015
alternative mrna splicing via spliceosomeGO:0000380600.014
cell migrationGO:00164772380.014
regulation of transportGO:00510491810.014
cellular response to molecule of bacterial originGO:007121930.014
regulation of mrna metabolic processGO:1903311720.014
nucleoside metabolic processGO:00091161270.014
sensory perception of chemical stimulusGO:00076061160.014
regulation of cell shapeGO:00083601130.014
regulation of rna splicingGO:0043484690.014
intracellular transportGO:00469072280.014
anterior posterior axis specification embryoGO:00085951030.014
regulation of cell morphogenesisGO:00226041630.014
hindbrain developmentGO:003090220.014
immune response activating signal transductionGO:000275720.014
response to biotic stimulusGO:00096072940.014
regulation of membrane potentialGO:0042391350.014
positive regulation of cell motilityGO:200014730.014
cell maturationGO:00484691440.014
response to other organismGO:00517072930.014
negative regulation of macromolecule biosynthetic processGO:00105582700.014
response to alcoholGO:0097305950.014
protein complex assemblyGO:00064612000.014
ribonucleotide metabolic processGO:00092591450.014
response to organonitrogen compoundGO:0010243750.014
mrna splicing via spliceosomeGO:0000398730.014
dendrite morphogenesisGO:00488131990.014
purine nucleoside triphosphate metabolic processGO:00091441190.014
regulation of organelle organizationGO:00330431960.014
epidermal growth factor receptor signaling pathwayGO:0007173580.014
estrogen metabolic processGO:000821010.014
protein maturationGO:0051604710.014
response to glucoseGO:000974920.014
cellular response to dna damage stimulusGO:00069742230.014
regulation of i kappab kinase nf kappab signalingGO:004312220.013
regulation of synapse structure and activityGO:00508031280.013
establishment of protein localizationGO:00451841630.013
erbb signaling pathwayGO:0038127580.013
positive regulation of cellular protein metabolic processGO:00322701180.013
chromatin organizationGO:00063252070.013
purine ribonucleoside triphosphate metabolic processGO:00092051190.013
nephron developmentGO:007200630.013
response to organophosphorusGO:004668320.013
cellular nitrogen compound catabolic processGO:00442701650.013
positive regulation of catabolic processGO:00098961050.013
single organism cellular localizationGO:19025801800.013
positive regulation of cellular catabolic processGO:0031331950.013
cellular ketone metabolic processGO:0042180240.013
carbohydrate derivative biosynthetic processGO:1901137850.013
glycosyl compound metabolic processGO:19016571270.013
rna splicing via transesterification reactionsGO:0000375730.013
regulation of cell cycle processGO:00105641810.013
salivary gland morphogenesisGO:00074351450.013
rhythmic behaviorGO:0007622760.013
regulation of immune system processGO:00026821760.013
response to alkaloidGO:0043279260.013
secretionGO:00469031090.013
negative regulation of cellular protein metabolic processGO:0032269850.013
regulation of immune responseGO:00507761180.013
regulation of epidermal growth factor receptor signaling pathwayGO:0042058420.013
organonitrogen compound biosynthetic processGO:19015661170.013
regulation of mrna splicing via spliceosomeGO:0048024640.013
matingGO:00076181200.013
negative regulation of protein metabolic processGO:0051248850.013
nucleotide metabolic processGO:00091171610.013
response to nitrogen compoundGO:1901698900.013
purine nucleotide metabolic processGO:00061631460.013
bolwig s organ developmentGO:005503480.013
glycosyl compound catabolic processGO:19016581120.013
posttranscriptional regulation of gene expressionGO:00106081450.013
anterior posterior axis specificationGO:00099481090.012
negative regulation of developmental processGO:00510932010.012
mitotic nuclear divisionGO:00070672130.012
mitotic cell cycle phase transitionGO:00447721380.012
organonitrogen compound catabolic processGO:19015651280.012
mrna processingGO:00063971040.012
negative regulation of cell deathGO:0060548810.012
chromatin modificationGO:00165681470.012
steroid catabolic processGO:000670610.012
cilium organizationGO:0044782410.012
cell adhesionGO:00071551360.012
regulation of response to biotic stimulusGO:0002831630.012
developmental programmed cell deathGO:00106231380.012
cilium morphogenesisGO:0060271390.012
purine nucleoside metabolic processGO:00422781270.012
embryonic axis specificationGO:00005781070.012
nucleoside phosphate catabolic processGO:19012921100.012
dorsal ventral pattern formationGO:00099531330.012
detection of stimulus involved in sensory perceptionGO:0050906920.012
detection of stimulusGO:00516061560.012
positive regulation of cell migrationGO:003033520.012
agingGO:00075681430.012
meiotic cell cycleGO:00513211710.012
ribonucleoside triphosphate metabolic processGO:00091991190.012
cell cycle phase transitionGO:00447701400.012
ion transportGO:00068111450.012
camera type eye morphogenesisGO:004859320.012
positive regulation of lipid storageGO:001088440.012
open tracheal system developmentGO:00074242040.012
purine containing compound catabolic processGO:00725231120.012
regulation of cellular response to stressGO:0080135890.012
cellular response to organic substanceGO:00713101320.012
immune response regulating signaling pathwayGO:000276420.012
cellular protein localizationGO:00346131600.012
transmembrane transportGO:00550851390.012
synapse organizationGO:00508081960.012
cellular response to carbohydrate stimulusGO:007132240.012
regulation of circadian rhythmGO:0042752490.012
positive regulation of cellular amine metabolic processGO:003324000.012
rho protein signal transductionGO:0007266140.012
protein processingGO:0016485680.012
carbohydrate derivative catabolic processGO:19011361180.012
purine nucleotide catabolic processGO:00061951090.012
autophagyGO:00069141080.012
negative regulation of nucleic acid templated transcriptionGO:19035072400.012
immune system processGO:00023763470.012
mesenchymal cell differentiationGO:004876210.011
establishment or maintenance of cell polarityGO:00071631670.011
regulation of multi organism processGO:00439001310.011
purine nucleoside triphosphate catabolic processGO:00091461080.011
embryonic development via the syncytial blastodermGO:00017001480.011
protein transportGO:00150311550.011
embryo development ending in birth or egg hatchingGO:00097921520.011
regulation of proteolysisGO:0030162870.011
mushroom body developmentGO:0016319700.011
regulation of cell projection organizationGO:0031344920.011
regulation of mitotic cell cycle phase transitionGO:19019901300.011
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.011
sex differentiationGO:0007548810.011
negative regulation of programmed cell deathGO:0043069720.011
response to hexoseGO:000974630.011
hematopoietic progenitor cell differentiationGO:000224410.011
positive regulation of mapk cascadeGO:0043410630.011
organophosphate catabolic processGO:00464341120.011
tripartite regional subdivisionGO:00073511030.011
gland morphogenesisGO:00226121450.011
retina development in camera type eyeGO:006004140.011
nephron epithelium developmentGO:007200930.011
purine nucleoside catabolic processGO:00061521120.011
ribose phosphate metabolic processGO:00196931450.011
molting cycle chitin based cuticleGO:0007591560.011
purine ribonucleoside catabolic processGO:00461301120.011
kidney morphogenesisGO:006099330.011
salt aversionGO:003519930.011
negative regulation of cell differentiationGO:00455961430.011
ribonucleotide catabolic processGO:00092611090.011
ribonucleoside catabolic processGO:00424541120.011
notch signaling pathwayGO:00072191200.011
regulation of response to external stimulusGO:00321011150.011
dendrite developmentGO:00163582040.011
regulation of hydrolase activityGO:0051336970.011
golgi organizationGO:0007030660.011
humoral immune responseGO:00069591170.011
sensory perception of painGO:001923340.011
heterocycle catabolic processGO:00467001660.011
cellular macromolecular complex assemblyGO:00346221530.011
regulation of cell cycle phase transitionGO:19019871300.011
multicellular organismal reproductive behaviorGO:00330571100.011
cytoplasmic transportGO:00164821300.011
nucleotide catabolic processGO:00091661090.011
ribonucleoside metabolic processGO:00091191270.011
central nervous system developmentGO:00074172010.011
homeostatic processGO:00425921990.010
nucleoside triphosphate catabolic processGO:00091431080.010
rna localizationGO:00064031150.010
synaptic transmissionGO:00072682880.010
limb developmentGO:006017310.010
response to external biotic stimulusGO:00432072930.010
hindgut developmentGO:0061525580.010
kidney epithelium developmentGO:007207330.010
respiratory system developmentGO:00605412130.010
purine ribonucleoside triphosphate catabolic processGO:00092071080.010
spermatid developmentGO:0007286980.010
gland developmentGO:00487321910.010
cation transmembrane transportGO:0098655880.010
positive regulation of hydrolase activityGO:0051345780.010
cytoskeleton dependent cytokinesisGO:0061640810.010
tissue morphogenesisGO:00487292970.010
positive regulation of developmental growthGO:0048639620.010
mesenchymal cell developmentGO:001403110.010
cell growthGO:00160491080.010
regulation of notch signaling pathwayGO:00085931000.010
eye antennal disc developmentGO:0035214600.010
synaptic target recognitionGO:0008039450.010
antimicrobial humoral responseGO:0019730990.010
positive regulation of nucleotide metabolic processGO:0045981550.010
regulation of protein modification processGO:00313991120.010
single organism membrane organizationGO:0044802930.010

GABA-B-R1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.030
nervous system diseaseDOID:86300.017
musculoskeletal system diseaseDOID:1700.013
disease of metabolismDOID:001466700.011
central nervous system diseaseDOID:33100.010