| protein modification by small protein conjugation or removal | GO:0070647 | 106 | 0.156 | Human |
| cellular catabolic process | GO:0044248 | 372 | 0.118 | |
| ribose phosphate metabolic process | GO:0019693 | 145 | 0.100 | |
| regulation of cellular component biogenesis | GO:0044087 | 201 | 0.090 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 79 | 0.087 | |
| positive regulation of nitrogen compound metabolic process | GO:0051173 | 354 | 0.083 | |
| cellular protein modification process | GO:0006464 | 438 | 0.078 | Human |
| positive regulation of gene expression | GO:0010628 | 290 | 0.076 | |
| catabolic process | GO:0009056 | 409 | 0.073 | |
| vesicle mediated transport | GO:0016192 | 381 | 0.072 | Human |
| nucleobase containing small molecule metabolic process | GO:0055086 | 174 | 0.071 | |
| regulation of molecular function | GO:0065009 | 217 | 0.069 | |
| intracellular signal transduction | GO:0035556 | 300 | 0.059 | |
| ribonucleotide metabolic process | GO:0009259 | 145 | 0.057 | |
| homeostatic process | GO:0042592 | 199 | 0.055 | |
| organonitrogen compound metabolic process | GO:1901564 | 318 | 0.054 | |
| protein localization | GO:0008104 | 284 | 0.054 | |
| protein modification by small protein conjugation | GO:0032446 | 79 | 0.053 | Human |
| macromolecule catabolic process | GO:0009057 | 161 | 0.052 | |
| nucleoside phosphate metabolic process | GO:0006753 | 162 | 0.049 | |
| protein modification process | GO:0036211 | 438 | 0.049 | Human |
| carbohydrate derivative metabolic process | GO:1901135 | 217 | 0.048 | |
| purine nucleoside metabolic process | GO:0042278 | 127 | 0.048 | |
| localization of cell | GO:0051674 | 257 | 0.047 | |
| cellular macromolecule catabolic process | GO:0044265 | 136 | 0.047 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 119 | 0.046 | |
| nucleotide metabolic process | GO:0009117 | 161 | 0.045 | |
| protein ubiquitination | GO:0016567 | 70 | 0.045 | Human |
| nucleoside triphosphate metabolic process | GO:0009141 | 120 | 0.045 | |
| positive regulation of biosynthetic process | GO:0009891 | 316 | 0.045 | |
| positive regulation of nucleic acid templated transcription | GO:1903508 | 266 | 0.043 | |
| organic substance catabolic process | GO:1901575 | 308 | 0.042 | |
| glycosyl compound catabolic process | GO:1901658 | 112 | 0.042 | |
| positive regulation of response to stimulus | GO:0048584 | 323 | 0.042 | Human |
| purine nucleotide metabolic process | GO:0006163 | 146 | 0.041 | |
| transcription from rna polymerase ii promoter | GO:0006366 | 368 | 0.041 | |
| organophosphate metabolic process | GO:0019637 | 195 | 0.039 | |
| blastoderm segmentation | GO:0007350 | 159 | 0.038 | |
| heterocycle catabolic process | GO:0046700 | 166 | 0.038 | |
| endocytosis | GO:0006897 | 310 | 0.037 | |
| regulation of intracellular signal transduction | GO:1902531 | 236 | 0.037 | |
| positive regulation of macromolecule biosynthetic process | GO:0010557 | 283 | 0.037 | |
| neurological system process | GO:0050877 | 358 | 0.036 | |
| regulation of phosphate metabolic process | GO:0019220 | 210 | 0.036 | |
| positive regulation of cellular biosynthetic process | GO:0031328 | 316 | 0.036 | |
| positive regulation of rna biosynthetic process | GO:1902680 | 266 | 0.036 | |
| small gtpase mediated signal transduction | GO:0007264 | 88 | 0.033 | |
| positive regulation of signaling | GO:0023056 | 243 | 0.033 | Human |
| regulation of catalytic activity | GO:0050790 | 185 | 0.032 | |
| cell death | GO:0008219 | 279 | 0.032 | |
| purine ribonucleotide metabolic process | GO:0009150 | 145 | 0.032 | |
| regulation of cellular catabolic process | GO:0031329 | 157 | 0.031 | |
| regulation of phosphorus metabolic process | GO:0051174 | 210 | 0.031 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 108 | 0.030 | |
| regulation of catabolic process | GO:0009894 | 170 | 0.030 | |
| programmed cell death | GO:0012501 | 257 | 0.030 | |
| regulation of transcription from rna polymerase ii promoter | GO:0006357 | 378 | 0.029 | Human |
| ribonucleoside metabolic process | GO:0009119 | 127 | 0.029 | |
| positive regulation of macromolecule metabolic process | GO:0010604 | 405 | 0.029 | |
| protein complex assembly | GO:0006461 | 200 | 0.029 | |
| nucleoside phosphate catabolic process | GO:1901292 | 110 | 0.029 | |
| proteolysis | GO:0006508 | 192 | 0.028 | |
| segmentation | GO:0035282 | 207 | 0.028 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 165 | 0.028 | |
| response to bacterium | GO:0009617 | 198 | 0.028 | |
| positive regulation of nucleobase containing compound metabolic process | GO:0045935 | 332 | 0.028 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 78 | 0.028 | |
| positive regulation of signal transduction | GO:0009967 | 223 | 0.027 | Human |
| epithelial cell development | GO:0002064 | 274 | 0.027 | |
| defense response | GO:0006952 | 300 | 0.027 | |
| regulation of response to stress | GO:0080134 | 200 | 0.027 | |
| enzyme linked receptor protein signaling pathway | GO:0007167 | 179 | 0.027 | Human |
| cellular component disassembly | GO:0022411 | 46 | 0.026 | |
| positive regulation of cell communication | GO:0010647 | 250 | 0.026 | Human |
| negative regulation of response to stimulus | GO:0048585 | 258 | 0.026 | |
| modification dependent protein catabolic process | GO:0019941 | 78 | 0.026 | |
| death | GO:0016265 | 284 | 0.026 | |
| positive regulation of transcription dna templated | GO:0045893 | 266 | 0.026 | |
| transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 116 | 0.025 | |
| positive regulation of phosphorus metabolic process | GO:0010562 | 139 | 0.025 | |
| nucleoside catabolic process | GO:0009164 | 112 | 0.025 | |
| regulation of nucleotide metabolic process | GO:0006140 | 62 | 0.025 | |
| ribonucleotide catabolic process | GO:0009261 | 109 | 0.025 | |
| wing disc morphogenesis | GO:0007472 | 344 | 0.024 | |
| response to nitrogen compound | GO:1901698 | 90 | 0.024 | |
| aromatic compound catabolic process | GO:0019439 | 166 | 0.024 | |
| glycosyl compound metabolic process | GO:1901657 | 127 | 0.023 | |
| nucleobase containing compound catabolic process | GO:0034655 | 165 | 0.023 | |
| intracellular transport | GO:0046907 | 228 | 0.023 | Human |
| purine containing compound metabolic process | GO:0072521 | 155 | 0.023 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 83 | 0.023 | |
| purine ribonucleotide catabolic process | GO:0009154 | 109 | 0.023 | |
| microtubule organizing center organization | GO:0031023 | 168 | 0.023 | |
| centrosome organization | GO:0051297 | 163 | 0.023 | |
| positive regulation of rna metabolic process | GO:0051254 | 271 | 0.022 | |
| cell migration | GO:0016477 | 238 | 0.022 | |
| positive regulation of cellular component organization | GO:0051130 | 156 | 0.022 | |
| cell motility | GO:0048870 | 251 | 0.022 | |
| organic cyclic compound catabolic process | GO:1901361 | 168 | 0.022 | |
| positive regulation of phosphate metabolic process | GO:0045937 | 139 | 0.022 | |
| protein complex biogenesis | GO:0070271 | 201 | 0.022 | |
| macromolecular complex assembly | GO:0065003 | 256 | 0.022 | |
| actin cytoskeleton organization | GO:0030036 | 206 | 0.022 | |
| regulation of multicellular organismal development | GO:2000026 | 414 | 0.022 | |
| single organism catabolic process | GO:0044712 | 228 | 0.021 | |
| establishment of planar polarity | GO:0001736 | 87 | 0.021 | |
| appendage morphogenesis | GO:0035107 | 397 | 0.020 | |
| positive regulation of ras gtpase activity | GO:0032320 | 36 | 0.020 | |
| defense response to other organism | GO:0098542 | 225 | 0.020 | |
| cellular macromolecular complex assembly | GO:0034622 | 153 | 0.020 | |
| imaginal disc derived wing morphogenesis | GO:0007476 | 337 | 0.020 | |
| axon development | GO:0061564 | 297 | 0.020 | |
| regulation of cell differentiation | GO:0045595 | 302 | 0.020 | |
| camera type eye development | GO:0043010 | 4 | 0.020 | |
| cellular homeostasis | GO:0019725 | 80 | 0.020 | |
| carbohydrate derivative catabolic process | GO:1901136 | 118 | 0.020 | |
| ribonucleoside catabolic process | GO:0042454 | 112 | 0.020 | |
| organophosphate catabolic process | GO:0046434 | 112 | 0.019 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 54 | 0.019 | |
| protein maturation | GO:0051604 | 71 | 0.019 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 108 | 0.019 | |
| positive regulation of cellular catabolic process | GO:0031331 | 95 | 0.019 | |
| small molecule metabolic process | GO:0044281 | 305 | 0.019 | |
| protein catabolic process | GO:0030163 | 101 | 0.019 | |
| ras protein signal transduction | GO:0007265 | 88 | 0.019 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 108 | 0.018 | |
| establishment of localization in cell | GO:0051649 | 402 | 0.018 | Human |
| purine ribonucleoside metabolic process | GO:0046128 | 127 | 0.018 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 119 | 0.018 | |
| phosphorylation | GO:0016310 | 294 | 0.018 | |
| purine ribonucleoside catabolic process | GO:0046130 | 112 | 0.018 | |
| connective tissue development | GO:0061448 | 3 | 0.018 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 119 | 0.018 | |
| digestive tract morphogenesis | GO:0048546 | 127 | 0.017 | |
| positive regulation of rab gtpase activity | GO:0032851 | 7 | 0.017 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 62 | 0.017 | |
| regulation of hydrolase activity | GO:0051336 | 97 | 0.017 | |
| columnar cuboidal epithelial cell differentiation | GO:0002065 | 256 | 0.017 | |
| positive regulation of catabolic process | GO:0009896 | 105 | 0.017 | |
| protein transport | GO:0015031 | 155 | 0.017 | |
| secretion by cell | GO:0032940 | 101 | 0.017 | |
| rna localization | GO:0006403 | 115 | 0.017 | |
| organonitrogen compound catabolic process | GO:1901565 | 128 | 0.017 | |
| ubiquitin homeostasis | GO:0010992 | 1 | 0.017 | |
| organic substance transport | GO:0071702 | 257 | 0.017 | |
| purine nucleoside catabolic process | GO:0006152 | 112 | 0.017 | |
| secretion | GO:0046903 | 109 | 0.017 | |
| protein processing | GO:0016485 | 68 | 0.017 | |
| central nervous system development | GO:0007417 | 201 | 0.017 | |
| phagocytosis | GO:0006909 | 215 | 0.016 | |
| appendage development | GO:0048736 | 401 | 0.016 | |
| cellular protein catabolic process | GO:0044257 | 83 | 0.016 | |
| g protein coupled receptor signaling pathway | GO:0007186 | 136 | 0.016 | |
| positive regulation of catalytic activity | GO:0043085 | 118 | 0.016 | |
| salivary gland development | GO:0007431 | 162 | 0.016 | |
| negative regulation of protein metabolic process | GO:0051248 | 85 | 0.016 | |
| nucleotide catabolic process | GO:0009166 | 109 | 0.015 | |
| cytoskeleton dependent cytokinesis | GO:0061640 | 81 | 0.015 | |
| peptidyl threonine phosphorylation | GO:0018107 | 2 | 0.015 | |
| regionalization | GO:0003002 | 416 | 0.015 | |
| regulation of small gtpase mediated signal transduction | GO:0051056 | 93 | 0.015 | |
| sensory organ morphogenesis | GO:0090596 | 260 | 0.015 | |
| cytoplasmic transport | GO:0016482 | 130 | 0.015 | |
| cellular macromolecule localization | GO:0070727 | 220 | 0.015 | |
| axon guidance | GO:0007411 | 233 | 0.015 | |
| single organism intracellular transport | GO:1902582 | 207 | 0.015 | Human |
| response to biotic stimulus | GO:0009607 | 294 | 0.015 | |
| autophagic cell death | GO:0048102 | 83 | 0.015 | |
| regulation of cellular amine metabolic process | GO:0033238 | 3 | 0.015 | |
| male gamete generation | GO:0048232 | 201 | 0.015 | |
| negative regulation of signal transduction | GO:0009968 | 206 | 0.014 | |
| negative regulation of signaling | GO:0023057 | 219 | 0.014 | |
| aging | GO:0007568 | 143 | 0.014 | |
| ovarian follicle cell development | GO:0030707 | 248 | 0.014 | |
| immune response | GO:0006955 | 246 | 0.014 | |
| regulation of protein modification process | GO:0031399 | 112 | 0.014 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 108 | 0.014 | |
| negative regulation of cellular metabolic process | GO:0031324 | 382 | 0.014 | |
| regulation of cellular response to stress | GO:0080135 | 89 | 0.014 | |
| regulation of protein metabolic process | GO:0051246 | 256 | 0.014 | |
| developmental programmed cell death | GO:0010623 | 138 | 0.014 | |
| regulation of localization | GO:0032879 | 275 | 0.014 | |
| purine containing compound catabolic process | GO:0072523 | 112 | 0.014 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 0 | 0.014 | |
| single organism carbohydrate metabolic process | GO:0044723 | 72 | 0.014 | |
| regulation of cellular protein metabolic process | GO:0032268 | 243 | 0.014 | |
| nucleoside metabolic process | GO:0009116 | 127 | 0.014 | |
| response to external biotic stimulus | GO:0043207 | 293 | 0.014 | |
| developmental maturation | GO:0021700 | 172 | 0.013 | |
| intracellular mrna localization involved in anterior posterior axis specification | GO:0060811 | 53 | 0.013 | |
| negative regulation of biosynthetic process | GO:0009890 | 277 | 0.013 | |
| regulation of ras protein signal transduction | GO:0046578 | 93 | 0.013 | |
| intracellular protein transport | GO:0006886 | 104 | 0.013 | |
| positive regulation of nucleotide metabolic process | GO:0045981 | 55 | 0.013 | |
| determination of adult lifespan | GO:0008340 | 137 | 0.013 | |
| organelle fission | GO:0048285 | 340 | 0.013 | |
| axis specification | GO:0009798 | 167 | 0.013 | |
| chromosome segregation | GO:0007059 | 157 | 0.013 | |
| imaginal disc derived appendage development | GO:0048737 | 399 | 0.013 | |
| macromolecular complex disassembly | GO:0032984 | 37 | 0.013 | |
| positive regulation of developmental process | GO:0051094 | 143 | 0.013 | |
| intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | GO:0070059 | 4 | 0.013 | |
| epithelial cell differentiation | GO:0030855 | 322 | 0.013 | |
| regulation of purine nucleotide catabolic process | GO:0033121 | 48 | 0.013 | |
| chemotaxis | GO:0006935 | 249 | 0.013 | |
| tissue morphogenesis | GO:0048729 | 297 | 0.013 | |
| cellular protein localization | GO:0034613 | 160 | 0.013 | |
| response to organic substance | GO:0010033 | 284 | 0.012 | |
| proteasomal protein catabolic process | GO:0010498 | 59 | 0.012 | |
| negative regulation of cell communication | GO:0010648 | 223 | 0.012 | |
| protein polyubiquitination | GO:0000209 | 11 | 0.012 | Human |
| tube morphogenesis | GO:0035239 | 191 | 0.012 | |
| protein phosphorylation | GO:0006468 | 169 | 0.012 | |
| taxis | GO:0042330 | 304 | 0.012 | |
| regulation of ras gtpase activity | GO:0032318 | 38 | 0.012 | |
| gland development | GO:0048732 | 191 | 0.012 | |
| establishment of protein localization | GO:0045184 | 163 | 0.012 | |
| negative regulation of macromolecule biosynthetic process | GO:0010558 | 270 | 0.012 | |
| cellular protein complex assembly | GO:0043623 | 71 | 0.011 | |
| guanosine containing compound metabolic process | GO:1901068 | 74 | 0.011 | |
| guanosine containing compound catabolic process | GO:1901069 | 74 | 0.011 | |
| regulation of anatomical structure morphogenesis | GO:0022603 | 242 | 0.011 | |
| amine metabolic process | GO:0009308 | 12 | 0.011 | |
| positive regulation of purine nucleotide catabolic process | GO:0033123 | 46 | 0.011 | |
| regulation of nucleotide catabolic process | GO:0030811 | 48 | 0.011 | |
| purine nucleotide catabolic process | GO:0006195 | 109 | 0.011 | |
| positive regulation of protein metabolic process | GO:0051247 | 128 | 0.011 | |
| cellular protein complex disassembly | GO:0043624 | 35 | 0.011 | |
| intrinsic apoptotic signaling pathway | GO:0097193 | 16 | 0.011 | |
| regulation of cell death | GO:0010941 | 173 | 0.011 | |
| nuclear division | GO:0000280 | 332 | 0.011 | |
| defense response to bacterium | GO:0042742 | 178 | 0.011 | |
| body morphogenesis | GO:0010171 | 2 | 0.011 | |
| embryonic pattern specification | GO:0009880 | 174 | 0.011 | |
| exocrine system development | GO:0035272 | 162 | 0.011 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 3 | 0.011 | |
| single organism membrane budding | GO:1902591 | 2 | 0.011 | |
| stem cell differentiation | GO:0048863 | 117 | 0.011 | |
| regulation of transport | GO:0051049 | 181 | 0.011 | |
| negative regulation of developmental process | GO:0051093 | 201 | 0.011 | |
| negative regulation of cell death | GO:0060548 | 81 | 0.010 | |
| regulation of immune system process | GO:0002682 | 176 | 0.010 | |
| tripartite regional subdivision | GO:0007351 | 103 | 0.010 | |
| positive regulation of hydrolase activity | GO:0051345 | 78 | 0.010 | |
| regulation of intracellular transport | GO:0032386 | 64 | 0.010 | |
| dna metabolic process | GO:0006259 | 227 | 0.010 | |
| post embryonic appendage morphogenesis | GO:0035120 | 385 | 0.010 | |
| regulation of cell morphogenesis | GO:0022604 | 163 | 0.010 | |
| regulation of translation | GO:0006417 | 56 | 0.010 | |
| forebrain development | GO:0030900 | 2 | 0.010 | |
| single organism biosynthetic process | GO:0044711 | 206 | 0.010 | |