IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

CG14634 (Dmel_CG14634)

CG14634 gene product from transcript CG14634-RB

(Aliases: Dmel\CG14634)

Entrez: 50366
FLYBASE: FBgn0040892
UniProtKB: Q9W5C8

Process Predictions
Disease Predictions

CG14634 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability
alditol phosphate metabolic process	GO:0052646	2	0.351
response to temperature stimulus	GO:0009266	106	0.256
response to organic substance	GO:0010033	284	0.215
response to cold	GO:0009409	13	0.206
response to abiotic stimulus	GO:0009628	341	0.189
cell proliferation	GO:0008283	299	0.139
central nervous system development	GO:0007417	201	0.138
response to alcohol	GO:0097305	95	0.137
response to ethanol	GO:0045471	59	0.136
response to oxygen containing compound	GO:1901700	200	0.112
olfactory behavior	GO:0042048	97	0.109
regulation of neurogenesis	GO:0050767	158	0.108
r7 cell differentiation	GO:0045466	43	0.089
neutral lipid metabolic process	GO:0006638	12	0.088
cellular carbohydrate metabolic process	GO:0044262	22	0.087
dendrite morphogenesis	GO:0048813	199	0.087
appendage morphogenesis	GO:0035107	397	0.075
wing disc morphogenesis	GO:0007472	344	0.073
triglyceride metabolic process	GO:0006641	12	0.072
regulation of cell differentiation	GO:0045595	302	0.072
small molecule metabolic process	GO:0044281	305	0.069
appendage development	GO:0048736	401	0.067
brain development	GO:0007420	120	0.064
male gamete generation	GO:0048232	201	0.059
tube morphogenesis	GO:0035239	191	0.059
regulation of nervous system development	GO:0051960	248	0.058
post embryonic appendage morphogenesis	GO:0035120	385	0.057
tube development	GO:0035295	244	0.056
carbohydrate derivative biosynthetic process	GO:1901137	85	0.056
imaginal disc derived appendage development	GO:0048737	399	0.055
forebrain development	GO:0030900	2	0.055
axis specification	GO:0009798	167	0.053
regulation of cell proliferation	GO:0042127	163	0.053
embryonic morphogenesis	GO:0048598	206	0.052
organophosphate biosynthetic process	GO:0090407	46	0.052
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.051
telencephalon development	GO:0021537	2	0.051
regulation of cell development	GO:0060284	215	0.051
rhythmic process	GO:0048511	106	0.050
embryonic pattern specification	GO:0009880	174	0.050
muscle structure development	GO:0061061	224	0.049
endocytosis	GO:0006897	310	0.048
imaginal disc derived wing morphogenesis	GO:0007476	337	0.048
single organism carbohydrate metabolic process	GO:0044723	72	0.046
acylglycerol metabolic process	GO:0006639	12	0.044
taxis	GO:0042330	304	0.043
glycerolipid metabolic process	GO:0046486	34	0.043
gland development	GO:0048732	191	0.043
gliogenesis	GO:0042063	80	0.041
regionalization	GO:0003002	416	0.040
respiratory system development	GO:0060541	213	0.039
dendrite development	GO:0016358	204	0.039
catabolic process	GO:0009056	409	0.039
neuron fate commitment	GO:0048663	50	0.038
vesicle mediated transport	GO:0016192	381	0.038
carbohydrate metabolic process	GO:0005975	82	0.037
phosphatidic acid metabolic process	GO:0046473	1	0.036
positive regulation of cellular biosynthetic process	GO:0031328	316	0.035
cellular amino acid metabolic process	GO:0006520	61	0.035
regulation of sequestering of triglyceride	GO:0010889	3	0.035
regulation of multicellular organismal development	GO:2000026	414	0.035
compound eye photoreceptor cell differentiation	GO:0001751	140	0.035
circadian rhythm	GO:0007623	105	0.034
dorsal ventral pattern formation	GO:0009953	133	0.034
wing disc pattern formation	GO:0035222	66	0.033
cellular amine metabolic process	GO:0044106	12	0.032
chemosensory behavior	GO:0007635	106	0.032
cellular response to organic substance	GO:0071310	132	0.032
phagocytosis	GO:0006909	215	0.032
regulation of cell fate commitment	GO:0010453	29	0.032
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.031
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.030
cell death	GO:0008219	279	0.030
rna localization	GO:0006403	115	0.030
response to other organism	GO:0051707	293	0.029
olfactory learning	GO:0008355	56	0.029
regulation of neuron differentiation	GO:0045664	103	0.029
growth	GO:0040007	359	0.029
regulation of cellular component biogenesis	GO:0044087	201	0.028
compound eye morphogenesis	GO:0001745	249	0.028
organic substance transport	GO:0071702	257	0.028
kidney development	GO:0001822	3	0.028
eye photoreceptor cell differentiation	GO:0001754	145	0.027
axonogenesis	GO:0007409	290	0.027
compound eye development	GO:0048749	307	0.027
triglyceride catabolic process	GO:0019433	3	0.026
response to organonitrogen compound	GO:0010243	75	0.026
renal system development	GO:0072001	72	0.026
head development	GO:0060322	135	0.026
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.025
response to drug	GO:0042493	17	0.025
chromatin silencing	GO:0006342	76	0.025
organonitrogen compound metabolic process	GO:1901564	318	0.025
death	GO:0016265	284	0.025
organic hydroxy compound metabolic process	GO:1901615	83	0.025
anion homeostasis	GO:0055081	3	0.025
negative regulation of response to stimulus	GO:0048585	258	0.025
acylglycerol catabolic process	GO:0046464	3	0.025
response to nitrogen compound	GO:1901698	90	0.025
developmental growth	GO:0048589	280	0.025
sterol homeostasis	GO:0055092	4	0.024
lipid metabolic process	GO:0006629	121	0.024
eye development	GO:0001654	323	0.024
protein localization	GO:0008104	284	0.024
positive regulation of sequestering of triglyceride	GO:0010890	1	0.023
programmed cell death	GO:0012501	257	0.023
regulation of cellular amine metabolic process	GO:0033238	3	0.023
tripartite regional subdivision	GO:0007351	103	0.023
defense response to bacterium	GO:0042742	178	0.022
phospholipid homeostasis	GO:0055091	1	0.022
localization of cell	GO:0051674	257	0.022
negative regulation of signal transduction	GO:0009968	206	0.022
triglyceride biosynthetic process	GO:0019432	2	0.022
regulation of cell death	GO:0010941	173	0.022
organic substance catabolic process	GO:1901575	308	0.022
negative regulation of nervous system development	GO:0051961	92	0.022
cellular response to endogenous stimulus	GO:0071495	80	0.022
apoptotic process	GO:0006915	159	0.022
cognition	GO:0050890	141	0.021
neutral lipid biosynthetic process	GO:0046460	2	0.021
morphogenesis of an epithelium	GO:0002009	276	0.021
photoreceptor cell fate commitment	GO:0046552	41	0.021
amine metabolic process	GO:0009308	12	0.021
glycerolipid catabolic process	GO:0046503	3	0.021
positive regulation of signaling	GO:0023056	243	0.021
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.021
phosphatidylethanolamine metabolic process	GO:0046337	1	0.021
regulation of organelle organization	GO:0033043	196	0.021
nucleus organization	GO:0006997	45	0.021
immune system process	GO:0002376	347	0.021
positive regulation of rna biosynthetic process	GO:1902680	266	0.021
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.020
positive regulation of cell communication	GO:0010647	250	0.020
photoreceptor cell differentiation	GO:0046530	170	0.020
urogenital system development	GO:0001655	72	0.020
negative regulation of cell communication	GO:0010648	223	0.020
embryonic development via the syncytial blastoderm	GO:0001700	148	0.020
carboxylic acid metabolic process	GO:0019752	92	0.020
establishment of localization in cell	GO:0051649	402	0.020
protein complex biogenesis	GO:0070271	201	0.020
response to lipopolysaccharide	GO:0032496	4	0.020
positive regulation of gene expression	GO:0010628	290	0.020
establishment of tissue polarity	GO:0007164	87	0.019
negative regulation of developmental process	GO:0051093	201	0.019
axon development	GO:0061564	297	0.019
response to biotic stimulus	GO:0009607	294	0.019
sensory organ morphogenesis	GO:0090596	260	0.019
segmentation	GO:0035282	207	0.019
regulation of transport	GO:0051049	181	0.019
carbohydrate derivative metabolic process	GO:1901135	217	0.019
camera type eye development	GO:0043010	4	0.019
positive regulation of response to stimulus	GO:0048584	323	0.019
positive regulation of biosynthetic process	GO:0009891	316	0.019
organic acid metabolic process	GO:0006082	103	0.019
neutral lipid catabolic process	GO:0046461	3	0.019
positive regulation of developmental process	GO:0051094	143	0.018
limb morphogenesis	GO:0035108	1	0.018
negative regulation of signaling	GO:0023057	219	0.018
negative regulation of rna biosynthetic process	GO:1902679	240	0.018
regulation of chromatin silencing	GO:0031935	36	0.018
neurological system process	GO:0050877	358	0.018
striated muscle cell differentiation	GO:0051146	90	0.018
organophosphate metabolic process	GO:0019637	195	0.018
positive regulation of lipid storage	GO:0010884	4	0.018
regulation of immune system process	GO:0002682	176	0.018
cell fate determination	GO:0001709	91	0.018
retina development in camera type eye	GO:0060041	4	0.018
negative regulation of cellular component organization	GO:0051129	108	0.018
single organism catabolic process	GO:0044712	228	0.018
regulation of multi organism process	GO:0043900	131	0.018
positive regulation of transcription dna templated	GO:0045893	266	0.018
anterior posterior pattern specification	GO:0009952	136	0.018
regulation of molecular function	GO:0065009	217	0.018
regulation of cell cycle	GO:0051726	291	0.017
regulation of response to stress	GO:0080134	200	0.017
regulation of protein metabolic process	GO:0051246	256	0.017
digestive tract morphogenesis	GO:0048546	127	0.017
stem cell proliferation	GO:0072089	88	0.017
positive regulation of rna metabolic process	GO:0051254	271	0.017
response to organic cyclic compound	GO:0014070	89	0.017
eye photoreceptor cell fate commitment	GO:0042706	37	0.017
branching morphogenesis of an epithelial tube	GO:0048754	45	0.017
response to nutrient levels	GO:0031667	114	0.017
spinal cord development	GO:0021510	1	0.017
exocrine system development	GO:0035272	162	0.017
response to hypoxia	GO:0001666	53	0.017
histolysis	GO:0007559	102	0.017
cell maturation	GO:0048469	144	0.017
regulation of cell fate specification	GO:0042659	27	0.016
oxoacid metabolic process	GO:0043436	103	0.016
cardiocyte differentiation	GO:0035051	29	0.016
transcription from rna polymerase ii promoter	GO:0006366	368	0.016
negative regulation of biosynthetic process	GO:0009890	277	0.016
gene silencing	GO:0016458	138	0.016
acylglycerol biosynthetic process	GO:0046463	2	0.016
blastoderm segmentation	GO:0007350	159	0.016
cellular catabolic process	GO:0044248	372	0.016
regulation of gene silencing	GO:0060968	63	0.016
cellular response to lipopolysaccharide	GO:0071222	3	0.016
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.016
camera type eye morphogenesis	GO:0048593	2	0.016
epithelial cell differentiation	GO:0030855	322	0.016
endodermal cell differentiation	GO:0035987	3	0.016
cellular response to biotic stimulus	GO:0071216	4	0.016
response to starvation	GO:0042594	97	0.016
positive regulation of catalytic activity	GO:0043085	118	0.016
axon guidance	GO:0007411	233	0.016
cytoskeleton dependent intracellular transport	GO:0030705	44	0.016
neuron projection guidance	GO:0097485	241	0.015
organic cyclic compound catabolic process	GO:1901361	168	0.015
mitochondrion organization	GO:0007005	65	0.015
cellular response to chemical stimulus	GO:0070887	199	0.015
anterior posterior axis specification	GO:0009948	109	0.015
negative regulation of cell death	GO:0060548	81	0.015
phosphorylation	GO:0016310	294	0.015
leg disc development	GO:0035218	92	0.015
open tracheal system development	GO:0007424	204	0.015
eye morphogenesis	GO:0048592	260	0.015
oocyte anterior posterior axis specification	GO:0007314	72	0.015
microtubule based transport	GO:0010970	42	0.015
limb development	GO:0060173	1	0.015
cell motility	GO:0048870	251	0.015
microtubule based movement	GO:0007018	51	0.015
chemotaxis	GO:0006935	249	0.015
protein heterooligomerization	GO:0051291	4	0.015
epithelial cell development	GO:0002064	274	0.015
body morphogenesis	GO:0010171	2	0.015
regulation of programmed cell death	GO:0043067	152	0.015
regulation of cellular ketone metabolic process	GO:0010565	3	0.015
cell fate specification	GO:0001708	71	0.015
response to external biotic stimulus	GO:0043207	293	0.015
regulation of lipid transport	GO:0032368	3	0.014
tissue migration	GO:0090130	155	0.014
single organism behavior	GO:0044708	391	0.014
memory	GO:0007613	94	0.014
response to extracellular stimulus	GO:0009991	116	0.014
cellular lipid metabolic process	GO:0044255	83	0.014
cholesterol transport	GO:0030301	2	0.014
regulation of notch signaling pathway	GO:0008593	100	0.014
cardiovascular system development	GO:0072358	82	0.014
cellular macromolecule localization	GO:0070727	220	0.014
larval development	GO:0002164	104	0.014
regulation of anatomical structure morphogenesis	GO:0022603	242	0.014
oocyte axis specification	GO:0007309	108	0.014
positive regulation of multi organism process	GO:0043902	40	0.014
response to oxygen levels	GO:0070482	59	0.014
negative regulation of cell differentiation	GO:0045596	143	0.014
instar larval development	GO:0002168	55	0.014
cellular response to molecule of bacterial origin	GO:0071219	3	0.014
response to organophosphorus	GO:0046683	2	0.014
response to endogenous stimulus	GO:0009719	119	0.013
response to gravity	GO:0009629	26	0.013
negative regulation of multicellular organismal process	GO:0051241	142	0.013
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.013
digestive system development	GO:0055123	149	0.013
positive regulation of cellular component biogenesis	GO:0044089	80	0.013
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.013
l amino acid import	GO:0043092	2	0.013
signal transduction by phosphorylation	GO:0023014	107	0.013
connective tissue development	GO:0061448	3	0.013
cellular response to hormone stimulus	GO:0032870	44	0.013
cytoplasm organization	GO:0007028	64	0.013
anterior posterior axis specification embryo	GO:0008595	103	0.013
endodermal cell fate commitment	GO:0001711	3	0.013
mushroom body development	GO:0016319	70	0.013
learning or memory	GO:0007611	141	0.013
ethanolamine containing compound metabolic process	GO:0042439	4	0.013
regulation of sterol transport	GO:0032371	1	0.013
oocyte differentiation	GO:0009994	145	0.013
morphogenesis of a branching structure	GO:0001763	45	0.013
regulation of catalytic activity	GO:0050790	185	0.013
regulation of neuron projection development	GO:0010975	69	0.013
salivary gland development	GO:0007431	162	0.013
transmembrane transport	GO:0055085	139	0.013
positive regulation of signal transduction	GO:0009967	223	0.012
immune response activating signal transduction	GO:0002757	2	0.012
regulation of epithelial cell proliferation	GO:0050678	4	0.012
response to hormone	GO:0009725	45	0.012
intracellular mrna localization involved in pattern specification process	GO:0060810	56	0.012
negative regulation of gene expression epigenetic	GO:0045814	77	0.012
cholesterol homeostasis	GO:0042632	3	0.012
homeostatic process	GO:0042592	199	0.012
tissue death	GO:0016271	102	0.012
cellular response to oxygen containing compound	GO:1901701	79	0.012
autophagy	GO:0006914	108	0.012
negative regulation of growth	GO:0045926	84	0.012
positive regulation of developmental growth	GO:0048639	62	0.012
intracellular mrna localization	GO:0008298	66	0.012
aging	GO:0007568	143	0.012
negative regulation of gene expression	GO:0010629	387	0.012
positive regulation of molecular function	GO:0044093	136	0.012
imaginal disc derived leg morphogenesis	GO:0007480	80	0.012
positive regulation of multicellular organismal process	GO:0051240	143	0.012
response to decreased oxygen levels	GO:0036293	58	0.012
hindbrain development	GO:0030902	2	0.012
negative regulation of rna metabolic process	GO:0051253	251	0.012
epithelial cell migration	GO:0010631	148	0.012
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.011
salivary gland morphogenesis	GO:0007435	145	0.011
regulation of cellular amino acid metabolic process	GO:0006521	0	0.011
cellular response to nitrogen compound	GO:1901699	51	0.011
gravitaxis	GO:0042332	26	0.011
associative learning	GO:0008306	65	0.011
macromolecular complex assembly	GO:0065003	256	0.011
response to peptide hormone	GO:0043434	29	0.011
regulation of cell projection organization	GO:0031344	92	0.011
response to copper ion	GO:0046688	4	0.011
nitrogen compound transport	GO:0071705	85	0.011
morphogenesis of embryonic epithelium	GO:0016331	94	0.011
nucleoside phosphate metabolic process	GO:0006753	162	0.011
learning	GO:0007612	75	0.011
pole plasm mrna localization	GO:0019094	49	0.011
regulation of cholesterol transport	GO:0032374	1	0.011
regulation of i kappab kinase nf kappab signaling	GO:0043122	2	0.011
organophosphate catabolic process	GO:0046434	112	0.011
muscle organ development	GO:0007517	127	0.011
negative regulation of transcription dna templated	GO:0045892	237	0.011
establishment or maintenance of cell polarity	GO:0007163	167	0.011
regulation of developmental growth	GO:0048638	174	0.011
developmental maturation	GO:0021700	172	0.011
regulation of protein complex assembly	GO:0043254	42	0.011
pole plasm assembly	GO:0007315	61	0.011
cation transport	GO:0006812	110	0.011
immune response regulating signaling pathway	GO:0002764	2	0.011
hindgut morphogenesis	GO:0007442	58	0.011
notch signaling pathway	GO:0007219	120	0.011
positive regulation of macromolecule metabolic process	GO:0010604	405	0.011
cuticle development	GO:0042335	86	0.011
regulation of synapse assembly	GO:0051963	94	0.011
mapk cascade	GO:0000165	107	0.011
ameboidal type cell migration	GO:0001667	151	0.011
positive regulation of transport	GO:0051050	92	0.011
macromolecule catabolic process	GO:0009057	161	0.011
muscle cell differentiation	GO:0042692	103	0.011
response to bacterium	GO:0009617	198	0.010
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.010
organonitrogen compound biosynthetic process	GO:1901566	117	0.010
dorsal ventral axis specification	GO:0009950	66	0.010
heart development	GO:0007507	82	0.010
convergent extension	GO:0060026	2	0.010
positive regulation of cell differentiation	GO:0045597	64	0.010
negative regulation of apoptotic process	GO:0043066	63	0.010
regulation of gene expression epigenetic	GO:0040029	128	0.010
intracellular transport	GO:0046907	228	0.010
cell cycle phase transition	GO:0044770	140	0.010
autophagic cell death	GO:0048102	83	0.010
jnk cascade	GO:0007254	50	0.010
long term memory	GO:0007616	62	0.010
cellular modified amino acid metabolic process	GO:0006575	45	0.010

CG14634 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.062
lipid metabolism disorder	DOID:3146	0.025
inherited metabolic disorder	DOID:655	0.025
disease of metabolism	DOID:0014667	0.025
familial hypertriglyceridemia	DOID:0050527	0.025
acquired metabolic disease	DOID:0060158	0.021
diabetes mellitus	DOID:9351	0.021
carbohydrate metabolism disease	DOID:0050013	0.021
glucose metabolism disease	DOID:4194	0.021
type 2 diabetes mellitus	DOID:9352	0.020
nervous system disease	DOID:863	0.018
integumentary system disease	DOID:16	0.017
hair disease	DOID:421	0.017
hypotrichosis	DOID:4535	0.017
familial hyperlipidemia	DOID:1168	0.016
familial combined hyperlipidemia	DOID:13809	0.016
familial lipoprotein lipase deficiency	DOID:14118	0.014
sensory system disease	DOID:0050155	0.013
cardiovascular system disease	DOID:1287	0.012

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