Drosophila melanogaster

14 known processes

Hex-A (Dmel_CG3001)

Hexokinase A

(Aliases: HEX-A,HK,Hex,HEX,Hex-A:B,Dmel\CG3001,DM1,CG3001)

Hex-A biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
lateral inhibitionGO:00463312060.198
Fly
neurological system processGO:00508773580.153
regulation of cell cycle processGO:00105641810.137
regulation of cell cycleGO:00517262910.092
meiotic cell cycle processGO:19030461320.090
cell cell signaling involved in cell fate commitmentGO:00451682100.086
Fly
macromolecular complex assemblyGO:00650032560.078
positive regulation of macromolecule biosynthetic processGO:00105572830.078
Human
appendage developmentGO:00487364010.075
epithelial cell differentiationGO:00308553220.075
oxidoreduction coenzyme metabolic processGO:000673320.073
Mouse
organonitrogen compound metabolic processGO:19015643180.073
Mouse
nad metabolic processGO:001967410.065
posttranscriptional gene silencingGO:0016441460.064
endocytosisGO:00068973100.063
ovarian follicle cell developmentGO:00307072480.062
eye developmentGO:00016543230.061
regulation of growthGO:00400082330.061
regulation of multicellular organismal developmentGO:20000264140.060
localization of cellGO:00516742570.060
regulation of cell deathGO:00109411730.057
gene silencingGO:00164581380.057
negative regulation of rna biosynthetic processGO:19026792400.057
single organism catabolic processGO:00447122280.057
Yeast
positive regulation of rna metabolic processGO:00512542710.056
organic cyclic compound catabolic processGO:19013611680.056
positive regulation of cellular biosynthetic processGO:00313283160.055
Human
nicotinamide nucleotide metabolic processGO:004649620.055
Mouse
organic substance catabolic processGO:19015753080.054
Yeast
developmental growthGO:00485892800.054
pigmentationGO:0043473750.053
response to lipopolysaccharideGO:003249640.051
organelle fissionGO:00482853400.051
cell cell junction organizationGO:0045216550.051
columnar cuboidal epithelial cell developmentGO:00020662490.051
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.050
regulation of transportGO:00510491810.050
Human Mouse
small molecule metabolic processGO:00442813050.050
Human Yeast Mouse
nuclear divisionGO:00002803320.050
aromatic compound catabolic processGO:00194391660.049
actin cytoskeleton organizationGO:00300362060.049
nucleoside phosphate metabolic processGO:00067531620.049
Mouse
intracellular signal transductionGO:00355563000.047
cellular ketone metabolic processGO:0042180240.047
Human
negative regulation of gene expressionGO:00106293870.047
programmed cell deathGO:00125012570.047
Mouse
epithelial cell developmentGO:00020642740.047
positive regulation of nucleobase containing compound metabolic processGO:00459353320.046
cell motilityGO:00488702510.046
chemotaxisGO:00069352490.046
positive regulation of macromolecule metabolic processGO:00106044050.046
Human
positive regulation of cell communicationGO:00106472500.045
Human Mouse
response to oxygen containing compoundGO:19017002000.044
Human
organonitrogen compound catabolic processGO:19015651280.044
phagocytosisGO:00069092150.044
cellular amino acid metabolic processGO:0006520610.044
cell proliferationGO:00082832990.043
notch signaling pathwayGO:00072191200.043
hindbrain developmentGO:003090220.042
mitotic nuclear divisionGO:00070672130.041
camera type eye developmentGO:004301040.041
growthGO:00400073590.040
imaginal disc derived appendage morphogenesisGO:00351143950.040
regulation of programmed cell deathGO:00430671520.040
nadh metabolic processGO:000673410.039
transcription from rna polymerase ii promoterGO:00063663680.038
negative regulation of nucleic acid templated transcriptionGO:19035072400.038
epidermis developmentGO:0008544650.037
negative regulation of cell proliferationGO:0008285690.036
embryo development ending in birth or egg hatchingGO:00097921520.036
axon developmentGO:00615642970.036
appendage morphogenesisGO:00351073970.036
vesicle mediated transportGO:00161923810.036
imaginal disc derived appendage developmentGO:00487373990.035
negative regulation of cell cycleGO:00457861160.035
regionalizationGO:00030024160.035
regulation of transcription from rna polymerase ii promoterGO:00063573780.034
single organism biosynthetic processGO:00447112060.034
Human
retina development in camera type eyeGO:006004140.034
cell junction organizationGO:0034330570.034
negative regulation of multicellular organismal processGO:00512411420.034
negative regulation of mitotic cell cycle phase transitionGO:19019911030.033
glutamate metabolic processGO:000653650.033
positive regulation of transcription dna templatedGO:00458932660.033
nephron developmentGO:007200630.033
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.032
cellular nitrogen compound catabolic processGO:00442701650.032
epithelial cell migrationGO:00106311480.032
cell migrationGO:00164772380.032
response to bacteriumGO:00096171980.032
regulation of intracellular signal transductionGO:19025312360.031
response to alcoholGO:0097305950.031
kidney developmentGO:000182230.031
wing disc morphogenesisGO:00074723440.031
detection of light stimulusGO:0009583580.030
response to light stimulusGO:00094161240.030
organic acid metabolic processGO:00060821030.030
Yeast
regulation of cellular ketone metabolic processGO:001056530.029
Human
positive regulation of nitrogen compound metabolic processGO:00511733540.029
catabolic processGO:00090564090.029
Yeast
carboxylic acid metabolic processGO:0019752920.029
Yeast
sensory perceptionGO:00076001960.028
regulation of apoptotic processGO:00429811300.028
energy derivation by oxidation of organic compoundsGO:0015980320.028
Human
regulation of phosphate metabolic processGO:00192202100.028
meiotic nuclear divisionGO:00071261510.028
negative regulation of cell cycle processGO:00109481090.028
imaginal disc derived wing morphogenesisGO:00074763370.027
axonogenesisGO:00074092900.027
cell adhesionGO:00071551360.027
actin filament based processGO:00300292200.027
positive regulation of signalingGO:00230562430.027
Human Mouse
positive regulation of nucleic acid templated transcriptionGO:19035082660.027
nucleobase containing small molecule metabolic processGO:00550861740.027
Mouse
oxoacid metabolic processGO:00434361030.026
Yeast
morphogenesis of an epitheliumGO:00020092760.026
regulation of cell developmentGO:00602842150.026
amine metabolic processGO:0009308120.026
negative regulation of transcription dna templatedGO:00458922370.026
positive regulation of cell deathGO:0010942690.025
heterocycle catabolic processGO:00467001660.025
regulation of cellular localizationGO:00603411360.024
Human Mouse
axon guidanceGO:00074112330.024
carbohydrate biosynthetic processGO:0016051170.024
Human
stem cell proliferationGO:0072089880.024
oxidation reduction processGO:00551141230.024
Human
cellular protein modification processGO:00064644380.024
purine nucleotide catabolic processGO:00061951090.023
columnar cuboidal epithelial cell differentiationGO:00020652560.023
regulation of cell cycle phase transitionGO:19019871300.023
negative regulation of cellular biosynthetic processGO:00313272770.023
Human
hair cell differentiationGO:0035315470.023
response to radiationGO:00093141550.023
cellular response to dna damage stimulusGO:00069742230.023
cell junction assemblyGO:0034329420.023
dorsal ventral pattern formationGO:00099531330.023
regulation of notch signaling pathwayGO:00085931000.023
meiotic cell cycleGO:00513211710.023
ras protein signal transductionGO:0007265880.023
forebrain developmentGO:003090020.023
cellular catabolic processGO:00442483720.023
negative regulation of nucleobase containing compound metabolic processGO:00459342610.022
positive regulation of gene expressionGO:00106282900.022
rna localizationGO:00064031150.022
detection of stimulusGO:00516061560.022
Human
brain developmentGO:00074201200.022
negative regulation of macromolecule biosynthetic processGO:00105582700.022
tissue morphogenesisGO:00487292970.022
telencephalon developmentGO:002153720.022
negative regulation of mitotic cell cycleGO:00459301090.022
nucleobase containing compound catabolic processGO:00346551650.022
regulation of protein metabolic processGO:00512462560.022
regulation of oocyte developmentGO:0060281270.022
body morphogenesisGO:001017120.021
post embryonic appendage morphogenesisGO:00351203850.021
deathGO:00162652840.021
Mouse
protein modification processGO:00362114380.021
negative regulation of biosynthetic processGO:00098902770.021
Human
ameboidal type cell migrationGO:00016671510.021
epidermal cell differentiationGO:0009913510.020
positive regulation of multicellular organismal processGO:00512401430.020
central nervous system developmentGO:00074172010.020
regulation of mitotic cell cycleGO:00073461900.020
single organism behaviorGO:00447083910.020
response to other organismGO:00517072930.020
sensory organ morphogenesisGO:00905962600.020
negative regulation of nitrogen compound metabolic processGO:00511722650.020
response to monosaccharideGO:003428440.020
Human
homeostatic processGO:00425921990.020
Human Mouse
apoptotic processGO:00069151590.020
Mouse
negative regulation of cell differentiationGO:00455961430.020
regulation of cell differentiationGO:00455953020.020
dna metabolic processGO:00062592270.020
phosphorylationGO:00163102940.020
positive regulation of developmental processGO:00510941430.020
positive regulation of cell migrationGO:003033520.019
positive regulation of cellular protein metabolic processGO:00322701180.019
synaptic target recognitionGO:0008039450.019
cellular component assembly involved in morphogenesisGO:00109271510.019
skin developmentGO:0043588650.019
taxisGO:00423303040.019
positive regulation of phosphorus metabolic processGO:00105621390.019
regulation of phosphorus metabolic processGO:00511742100.019
metal ion transportGO:0030001740.019
Mouse
posttranscriptional gene silencing by rnaGO:0035194450.019
epithelial tube morphogenesisGO:0060562880.019
regulation of epithelial cell differentiationGO:003085640.018
mitotic spindle organizationGO:00070522200.018
heart morphogenesisGO:0003007320.018
positive regulation of phosphate metabolic processGO:00459371390.018
gliogenesisGO:0042063800.018
nephron epithelium developmentGO:007200930.018
neuronal action potentialGO:0019228100.018
regulation of cell proliferationGO:00421271630.018
open tracheal system developmentGO:00074242040.018
purine ribonucleotide metabolic processGO:00091501450.018
positive regulation of cellular component biogenesisGO:0044089800.018
smoothened signaling pathwayGO:0007224490.018
small gtpase mediated signal transductionGO:0007264880.018
neuroblast proliferationGO:0007405740.017
acetylcholine metabolic processGO:000829120.017
nitrogen compound transportGO:0071705850.017
Human Mouse
regulation of localizationGO:00328792750.017
Human Mouse
alpha amino acid metabolic processGO:1901605200.017
choline catabolic processGO:004242610.017
positive regulation of catabolic processGO:00098961050.017
cellular macromolecule catabolic processGO:00442651360.017
ribonucleotide catabolic processGO:00092611090.017
single organism cell adhesionGO:0098602470.017
detection of stimulus involved in sensory perceptionGO:0050906920.017
response to organic cyclic compoundGO:0014070890.017
carbohydrate derivative metabolic processGO:19011352170.017
Human Yeast Mouse
regulation of gene expression epigeneticGO:00400291280.017
positive regulation of cell motilityGO:200014730.016
purine containing compound catabolic processGO:00725231120.016
regulation of cellular amine metabolic processGO:003323830.016
posttranscriptional regulation of gene expressionGO:00106081450.016
cell cell junction assemblyGO:0007043380.016
detection of external stimulusGO:0009581660.016
memoryGO:0007613940.016
ribose phosphate metabolic processGO:00196931450.016
gene silencing by rnaGO:0031047570.016
cell divisionGO:00513012480.016
neuron projection guidanceGO:00974852410.016
heart developmentGO:0007507820.016
response to endogenous stimulusGO:00097191190.016
carbohydrate metabolic processGO:0005975820.016
regulation of mapk cascadeGO:0043408920.015
cellular response to organic substanceGO:00713101320.015
chromosome organizationGO:00512763600.015
positive regulation of biosynthetic processGO:00098913160.015
Human
establishment of blood nerve barrierGO:000806520.015
ribonucleotide metabolic processGO:00092591450.015
epithelium migrationGO:00901321480.015
imaginal disc derived wing hair organizationGO:0035317450.015
wound healingGO:0042060750.015
negative regulation of cell cycle phase transitionGO:19019881030.015
pyridine containing compound metabolic processGO:007252430.015
Mouse
non sensory hair organizationGO:0035316470.015
imaginal disc pattern formationGO:0007447910.015
regulation of organelle organizationGO:00330431960.015
cellular response to chemical stimulusGO:00708871990.014
organophosphate metabolic processGO:00196371950.014
Human Yeast Mouse
nucleobase containing compound transportGO:0015931560.014
positive regulation of programmed cell deathGO:0043068620.014
regulation of steroid metabolic processGO:001921820.014
chaeta developmentGO:0022416970.014
positive regulation of response to stimulusGO:00485843230.014
positive regulation of transportGO:0051050920.014
Human Mouse
anatomical structure homeostasisGO:0060249970.014
positive regulation of lipid metabolic processGO:004583440.014
deactivation of rhodopsin mediated signalingGO:0016059170.014
acyl coa metabolic processGO:000663730.014
positive regulation of organelle organizationGO:0010638650.014
nucleoside phosphate catabolic processGO:19012921100.014
response to organic substanceGO:00100332840.014
Human
regulation of mitotic cell cycle phase transitionGO:19019901300.014
response to hexoseGO:000974630.014
Human
larval developmentGO:00021641040.014
regulation of cellular protein metabolic processGO:00322682430.014
spindle organizationGO:00070512530.014
regulation of hydrolase activityGO:0051336970.014
eye morphogenesisGO:00485922600.014
cuticle developmentGO:0042335860.014
regulation of ras protein signal transductionGO:0046578930.014
positive regulation of signal transductionGO:00099672230.013
negative regulation of developmental processGO:00510932010.013
hematopoietic or lymphoid organ developmentGO:0048534570.013
regulation of microtubule cytoskeleton organizationGO:0070507410.013
tissue migrationGO:00901301550.013
detection of abiotic stimulusGO:0009582660.013
embryonic development via the syncytial blastodermGO:00017001480.013
purine nucleotide metabolic processGO:00061631460.013
heart contractionGO:0060047260.013
g protein coupled receptor signaling pathwayGO:00071861360.013
stem cell divisionGO:0017145690.013
cell fate determinationGO:0001709910.013
regulation of small gtpase mediated signal transductionGO:0051056930.013
regulation of catalytic activityGO:00507901850.013
cellular amine metabolic processGO:0044106120.013
positive regulation of cellular catabolic processGO:0031331950.013
cellular response to ethanolGO:007136140.013
choline metabolic processGO:001969510.013
regulation of epidermal cell differentiationGO:004560430.013
intracellular transportGO:00469072280.012
regulation of cellular amino acid metabolic processGO:000652100.012
negative regulation of cell deathGO:0060548810.012
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.012
chromosome segregationGO:00070591570.012
neural precursor cell proliferationGO:0061351750.012
organic hydroxy compound biosynthetic processGO:1901617210.012
negative regulation of rna metabolic processGO:00512532510.012
positive regulation of rna biosynthetic processGO:19026802660.012
positive regulation of molecular functionGO:00440931360.012
regulation of embryonic developmentGO:0045995680.012
purine containing compound metabolic processGO:00725211550.012
cell maturationGO:00484691440.012
connective tissue developmentGO:006144830.012
positive regulation of purine nucleotide catabolic processGO:0033123460.012
positive regulation of protein metabolic processGO:00512471280.012
regulation of phosphorylationGO:00423251470.012
kidney morphogenesisGO:006099330.012
stem cell maintenanceGO:0019827670.012
regulation of membrane potentialGO:0042391350.012
photoreceptor cell differentiationGO:00465301700.012
negative regulation of growthGO:0045926840.012
female meiosis chromosome segregationGO:0016321330.012
hormone catabolic processGO:004244730.012
endomembrane system organizationGO:00102561190.012
kidney epithelium developmentGO:007207330.012
regulation of purine nucleotide metabolic processGO:1900542620.012
ethanolamine containing compound metabolic processGO:004243940.012
cell cycle phase transitionGO:00447701400.012
secretionGO:00469031090.012
Human Mouse Rat
acetylcholine catabolic processGO:000658110.011
dna replicationGO:0006260480.011
cell deathGO:00082192790.011
Mouse
regulation of cytoskeleton organizationGO:0051493890.011
adult behaviorGO:00305341370.011
mapk cascadeGO:00001651070.011
pyruvate metabolic processGO:000609070.011
Yeast
regulation of neuron differentiationGO:00456641030.011
anterior posterior pattern specificationGO:00099521360.011
nephron tubule developmentGO:007208030.011
regulation of glial cell differentiationGO:004568510.011
purine ribonucleotide catabolic processGO:00091541090.011
response to glucoseGO:000974920.011
Human
developmental maturationGO:00217001720.011
regulation of meiosisGO:004002030.011
nucleotide metabolic processGO:00091171610.011
Mouse
response to biotic stimulusGO:00096072940.011
regulation of cell junction assemblyGO:190188820.011
nucleotide catabolic processGO:00091661090.011
protein phosphorylationGO:00064681690.011
cell agingGO:000756920.011
regulation of protein complex disassemblyGO:0043244290.011
long term memoryGO:0007616620.011
synapse organizationGO:00508081960.011
proteolysisGO:00065081920.011
cell fate commitment involved in pattern specificationGO:0060581310.011
cell growthGO:00160491080.011
respiratory system developmentGO:00605412130.011
tricarboxylic acid metabolic processGO:007235010.011
stem cell differentiationGO:00488631170.010
regulation of response to dna damage stimulusGO:2001020230.010
cellular homeostasisGO:0019725800.010
Mouse
glial cell proliferationGO:0014009130.010
positive regulation of intracellular signal transductionGO:19025331160.010
regulation of microtubule polymerization or depolymerizationGO:0031110270.010
regulation of gene silencingGO:0060968630.010
response to nutrient levelsGO:00316671140.010
compound eye developmentGO:00487493070.010
oocyte axis specificationGO:00073091080.010
immune system developmentGO:0002520570.010
neuronal stem cell maintenanceGO:009715040.010
maintenance of imaginal disc derived wing hair orientationGO:003532130.010
regulation of catabolic processGO:00098941700.010
positive regulation of cell differentiationGO:0045597640.010
organelle assemblyGO:00709251980.010

Hex-A disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.035
glucose metabolism diseaseDOID:419400.018
Human
acquired metabolic diseaseDOID:006015800.018
Human
disease of metabolismDOID:001466700.018
Human
carbohydrate metabolism diseaseDOID:005001300.018
Human
nervous system diseaseDOID:86300.016
musculoskeletal system diseaseDOID:1700.016