IMP: Integrative Multi-species Prediction

Drosophila melanogaster

9 known processes

Gr21a (Dmel_CG13948)

Gustatory receptor 21a

(Aliases: 21D.1,CG13948,Dmel\CG13948,GR21a,GR21D1,(GR) 21a,GR21D.1,Gr21D1,DmGr21a)

Entrez: 33251
FLYBASE: FBgn0041250
UniProtKB: Q9VPT1
UniProtKB: M9PAZ2

Process Predictions
Disease Predictions

Gr21a biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
detection of stimulus	GO:0051606	156	0.198
detection of stimulus involved in sensory perception	GO:0050906	92	0.196
detection of chemical stimulus involved in sensory perception	GO:0050907	75	0.177
detection of chemical stimulus involved in sensory perception of smell	GO:0050911	50	0.147
sensory perception	GO:0007600	196	0.109
detection of chemical stimulus	GO:0009593	93	0.100
neurological system process	GO:0050877	358	0.074
exocrine system development	GO:0035272	162	0.074
defense response	GO:0006952	300	0.055
open tracheal system development	GO:0007424	204	0.052
ovarian follicle cell development	GO:0030707	248	0.052
regionalization	GO:0003002	416	0.050
response to biotic stimulus	GO:0009607	294	0.048
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.046
salivary gland morphogenesis	GO:0007435	145	0.046
response to bacterium	GO:0009617	198	0.046
tissue morphogenesis	GO:0048729	297	0.045
gland morphogenesis	GO:0022612	145	0.044
wing disc morphogenesis	GO:0007472	344	0.043
sensory perception of chemical stimulus	GO:0007606	116	0.043
developmental maturation	GO:0021700	172	0.041
response to external biotic stimulus	GO:0043207	293	0.040
cellular component assembly involved in morphogenesis	GO:0010927	151	0.039
immune system process	GO:0002376	347	0.038
columnar cuboidal epithelial cell development	GO:0002066	249	0.038
appendage morphogenesis	GO:0035107	397	0.037
taxis	GO:0042330	304	0.037
appendage development	GO:0048736	401	0.036
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.036
developmental programmed cell death	GO:0010623	138	0.036
epithelial cell development	GO:0002064	274	0.036
imaginal disc derived appendage development	GO:0048737	399	0.036
response to other organism	GO:0051707	293	0.035
chorion containing eggshell formation	GO:0007304	105	0.035
response to abiotic stimulus	GO:0009628	341	0.035
salivary gland development	GO:0007431	162	0.033
morphogenesis of an epithelium	GO:0002009	276	0.033
defense response to other organism	GO:0098542	225	0.032
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.032
lateral inhibition	GO:0046331	206	0.031
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.031
positive regulation of cellular biosynthetic process	GO:0031328	316	0.031
negative regulation of response to stimulus	GO:0048585	258	0.031
defense response to bacterium	GO:0042742	178	0.031
localization of cell	GO:0051674	257	0.031
digestive tract morphogenesis	GO:0048546	127	0.031
tissue death	GO:0016271	102	0.030
segmentation	GO:0035282	207	0.029
salivary gland cell autophagic cell death	GO:0035071	83	0.029
sensory perception of smell	GO:0007608	80	0.029
vesicle mediated transport	GO:0016192	381	0.029
positive regulation of biosynthetic process	GO:0009891	316	0.029
regulation of cell differentiation	GO:0045595	302	0.028
post embryonic appendage morphogenesis	GO:0035120	385	0.028
cell migration	GO:0016477	238	0.027
positive regulation of rna biosynthetic process	GO:1902680	266	0.027
histolysis	GO:0007559	102	0.027
imaginal disc derived wing morphogenesis	GO:0007476	337	0.027
kidney development	GO:0001822	3	0.027
single organism behavior	GO:0044708	391	0.027
dendrite development	GO:0016358	204	0.027
cell death	GO:0008219	279	0.027
stem cell differentiation	GO:0048863	117	0.026
multi organism behavior	GO:0051705	175	0.026
detection of abiotic stimulus	GO:0009582	66	0.026
regulation of localization	GO:0032879	275	0.026
cell motility	GO:0048870	251	0.026
immune response	GO:0006955	246	0.025
digestive tract development	GO:0048565	149	0.025
blastoderm segmentation	GO:0007350	159	0.025
organelle assembly	GO:0070925	198	0.025
organonitrogen compound metabolic process	GO:1901564	318	0.025
response to organic substance	GO:0010033	284	0.025
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.025
endocytosis	GO:0006897	310	0.024
mating behavior	GO:0007617	106	0.024
embryonic pattern specification	GO:0009880	174	0.024
regulation of multicellular organismal development	GO:2000026	414	0.024
respiratory system development	GO:0060541	213	0.024
regulation of cell cycle	GO:0051726	291	0.024
positive regulation of cell communication	GO:0010647	250	0.023
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.023
positive regulation of response to stimulus	GO:0048584	323	0.023
digestive system development	GO:0055123	149	0.023
intracellular signal transduction	GO:0035556	300	0.023
positive regulation of signal transduction	GO:0009967	223	0.023
phagocytosis	GO:0006909	215	0.023
detection of external stimulus	GO:0009581	66	0.023
positive regulation of signaling	GO:0023056	243	0.023
regulation of mitotic cell cycle	GO:0007346	190	0.022
epithelial cell differentiation	GO:0030855	322	0.022
anterior posterior pattern specification	GO:0009952	136	0.022
gland development	GO:0048732	191	0.022
regulation of organelle organization	GO:0033043	196	0.022
mesoderm development	GO:0007498	78	0.022
programmed cell death	GO:0012501	257	0.022
cell maturation	GO:0048469	144	0.022
axis specification	GO:0009798	167	0.022
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.021
death	GO:0016265	284	0.021
macromolecular complex assembly	GO:0065003	256	0.021
hindgut morphogenesis	GO:0007442	58	0.021
hindgut development	GO:0061525	58	0.021
regulation of anatomical structure morphogenesis	GO:0022603	242	0.021
mating	GO:0007618	120	0.021
photoreceptor cell differentiation	GO:0046530	170	0.021
melanization defense response	GO:0035006	45	0.021
body morphogenesis	GO:0010171	2	0.021
peptide metabolic process	GO:0006518	80	0.020
compound eye development	GO:0048749	307	0.020
establishment of localization in cell	GO:0051649	402	0.020
salivary gland histolysis	GO:0035070	88	0.020
multi multicellular organism process	GO:0044706	123	0.020
regulation of transport	GO:0051049	181	0.020
synaptic transmission	GO:0007268	288	0.019
positive regulation of gene expression	GO:0010628	290	0.019
reproductive behavior	GO:0019098	122	0.019
eggshell formation	GO:0030703	105	0.019
regulation of nervous system development	GO:0051960	248	0.019
small molecule metabolic process	GO:0044281	305	0.019
dorsal ventral pattern formation	GO:0009953	133	0.019
positive regulation of rna metabolic process	GO:0051254	271	0.018
innate immune response	GO:0045087	144	0.018
pigment metabolic process	GO:0042440	84	0.018
autophagic cell death	GO:0048102	83	0.018
tube morphogenesis	GO:0035239	191	0.018
embryonic morphogenesis	GO:0048598	206	0.018
inter male aggressive behavior	GO:0002121	60	0.018
regulation of cell cycle process	GO:0010564	181	0.018
hindbrain development	GO:0030902	2	0.018
organic substance catabolic process	GO:1901575	308	0.018
catabolic process	GO:0009056	409	0.018
compound eye morphogenesis	GO:0001745	249	0.018
negative regulation of mitotic cell cycle	GO:0045930	109	0.017
response to lipopolysaccharide	GO:0032496	4	0.017
behavioral response to pain	GO:0048266	3	0.017
oocyte differentiation	GO:0009994	145	0.017
establishment or maintenance of cell polarity	GO:0007163	167	0.017
embryonic axis specification	GO:0000578	107	0.017
nephron development	GO:0072006	3	0.017
nuclear division	GO:0000280	332	0.017
negative regulation of cell cycle process	GO:0010948	109	0.017
proteolysis	GO:0006508	192	0.017
ameboidal type cell migration	GO:0001667	151	0.017
eye morphogenesis	GO:0048592	260	0.017
compound eye photoreceptor cell differentiation	GO:0001751	140	0.017
protein complex assembly	GO:0006461	200	0.017
transcription from rna polymerase ii promoter	GO:0006366	368	0.016
multicellular organismal reproductive behavior	GO:0033057	110	0.016
cellular protein modification process	GO:0006464	438	0.016
eye photoreceptor cell fate commitment	GO:0042706	37	0.016
negative regulation of cell communication	GO:0010648	223	0.016
melanin metabolic process	GO:0006582	47	0.016
multi organism reproductive behavior	GO:0044705	121	0.016
rhythmic behavior	GO:0007622	76	0.016
locomotory behavior	GO:0007626	176	0.016
cell division	GO:0051301	248	0.016
connective tissue development	GO:0061448	3	0.016
tube development	GO:0035295	244	0.016
wound healing spreading of epidermal cells	GO:0035313	1	0.016
anterior posterior axis specification embryo	GO:0008595	103	0.016
cellular catabolic process	GO:0044248	372	0.016
sensory perception of mechanical stimulus	GO:0050954	72	0.016
negative regulation of cell cycle	GO:0045786	116	0.016
purine ribonucleotide metabolic process	GO:0009150	145	0.015
positive regulation of transcription dna templated	GO:0045893	266	0.015
male courtship behavior	GO:0008049	63	0.015
tripartite regional subdivision	GO:0007351	103	0.015
response to wounding	GO:0009611	94	0.015
chemosensory behavior	GO:0007635	106	0.015
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.015
renal tubule morphogenesis	GO:0061333	44	0.015
purine nucleotide metabolic process	GO:0006163	146	0.015
detection of light stimulus	GO:0009583	58	0.015
negative regulation of cell cycle phase transition	GO:1901988	103	0.015
tissue migration	GO:0090130	155	0.015
single organism catabolic process	GO:0044712	228	0.015
cellular response to oxygen containing compound	GO:1901701	79	0.015
amine metabolic process	GO:0009308	12	0.014
photoreceptor cell fate commitment	GO:0046552	41	0.014
negative regulation of cell differentiation	GO:0045596	143	0.014
olfactory behavior	GO:0042048	97	0.014
positive regulation of macromolecule metabolic process	GO:0010604	405	0.014
imaginal disc pattern formation	GO:0007447	91	0.014
multicellular organismal aging	GO:0010259	140	0.014	Fly
sensory organ morphogenesis	GO:0090596	260	0.014
mitotic cell cycle phase transition	GO:0044772	138	0.014
negative regulation of developmental process	GO:0051093	201	0.014
nucleobase containing small molecule metabolic process	GO:0055086	174	0.014
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.014
embryonic hindgut morphogenesis	GO:0048619	48	0.014
epithelium migration	GO:0090132	148	0.014
single organism cellular localization	GO:1902580	180	0.014
homeostatic process	GO:0042592	199	0.014
negative regulation of cellular biosynthetic process	GO:0031327	277	0.014
determination of adult lifespan	GO:0008340	137	0.014	Fly
actin cytoskeleton organization	GO:0030036	206	0.014
apoptotic process	GO:0006915	159	0.013
anterior posterior axis specification	GO:0009948	109	0.013
g2 dna damage checkpoint	GO:0031572	69	0.013
chaeta development	GO:0022416	97	0.013
protein modification process	GO:0036211	438	0.013
cell proliferation	GO:0008283	299	0.013
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.013
regulation of immune system process	GO:0002682	176	0.013
regulation of neurogenesis	GO:0050767	158	0.013
forebrain development	GO:0030900	2	0.013
phosphorylation	GO:0016310	294	0.013
malpighian tubule development	GO:0072002	64	0.013
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.013
regulation of cell morphogenesis	GO:0022604	163	0.013
cellular response to abiotic stimulus	GO:0071214	58	0.013
negative regulation of signaling	GO:0023057	219	0.013
cell cycle phase transition	GO:0044770	140	0.013
carboxylic acid metabolic process	GO:0019752	92	0.013
cilium morphogenesis	GO:0060271	39	0.013
morphogenesis of a polarized epithelium	GO:0001738	93	0.013
anatomical structure homeostasis	GO:0060249	97	0.013
renal system development	GO:0072001	72	0.013
cellular response to chemical stimulus	GO:0070887	199	0.013
oocyte development	GO:0048599	124	0.013
oocyte construction	GO:0007308	112	0.013
defense response to gram negative bacterium	GO:0050829	94	0.012
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.012
drinking behavior	GO:0042756	2	0.012
actin filament based process	GO:0030029	220	0.012
response to light stimulus	GO:0009416	124	0.012
maternal determination of anterior posterior axis embryo	GO:0008358	74	0.012
regulation of cellular component biogenesis	GO:0044087	201	0.012
protein complex biogenesis	GO:0070271	201	0.012
establishment of tissue polarity	GO:0007164	87	0.012
regulation of cell morphogenesis involved in differentiation	GO:0010769	61	0.012
regulation of cellular ketone metabolic process	GO:0010565	3	0.012
regulation of anatomical structure size	GO:0090066	163	0.012
male gamete generation	GO:0048232	201	0.012
oocyte axis specification	GO:0007309	108	0.012
cell projection assembly	GO:0030031	94	0.012
endomembrane system organization	GO:0010256	119	0.012
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.012
dendrite morphogenesis	GO:0048813	199	0.012
chemotaxis	GO:0006935	249	0.012
cellular response to molecule of bacterial origin	GO:0071219	3	0.012
ethanolamine containing compound metabolic process	GO:0042439	4	0.012
epithelial cell migration	GO:0010631	148	0.012
cellular amine metabolic process	GO:0044106	12	0.012
negative regulation of gene expression	GO:0010629	387	0.012
protein maturation	GO:0051604	71	0.012
adult locomotory behavior	GO:0008344	76	0.012
sensory perception of pain	GO:0019233	4	0.012
water homeostasis	GO:0030104	3	0.012
regulation of response to stress	GO:0080134	200	0.012
intracellular transport	GO:0046907	228	0.012
dorsal ventral axis specification	GO:0009950	66	0.012
purine ribonucleoside metabolic process	GO:0046128	127	0.012
regulation of cellular amine metabolic process	GO:0033238	3	0.012
phenol containing compound metabolic process	GO:0018958	57	0.012
organic acid metabolic process	GO:0006082	103	0.012
camera type eye development	GO:0043010	4	0.012
cellular amino acid metabolic process	GO:0006520	61	0.011
response to hypoxia	GO:0001666	53	0.011
male mating behavior	GO:0060179	70	0.011
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.011
nucleoside phosphate metabolic process	GO:0006753	162	0.011
microtubule based movement	GO:0007018	51	0.011
organonitrogen compound catabolic process	GO:1901565	128	0.011
kidney morphogenesis	GO:0060993	3	0.011
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.011
immune response activating signal transduction	GO:0002757	2	0.011
cytoplasm organization	GO:0007028	64	0.011
mitotic nuclear division	GO:0007067	213	0.011
organic substance transport	GO:0071702	257	0.011
hematopoietic progenitor cell differentiation	GO:0002244	1	0.011
regulation of phosphorus metabolic process	GO:0051174	210	0.011
regulation of notch signaling pathway	GO:0008593	100	0.011
eye antennal disc morphogenesis	GO:0007455	34	0.011
epithelial tube morphogenesis	GO:0060562	88	0.011
ribose phosphate metabolic process	GO:0019693	145	0.011
regulation of intracellular signal transduction	GO:1902531	236	0.011
regulation of epithelial cell differentiation	GO:0030856	4	0.011
response to organophosphorus	GO:0046683	2	0.011
pigmentation	GO:0043473	75	0.011
cellular ketone metabolic process	GO:0042180	24	0.011
negative regulation of multicellular organismal process	GO:0051241	142	0.011
protein localization	GO:0008104	284	0.011
cellular response to dna damage stimulus	GO:0006974	223	0.011
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.011
mesenchymal cell differentiation	GO:0048762	1	0.011
eye development	GO:0001654	323	0.011
carbohydrate derivative metabolic process	GO:1901135	217	0.011
single organism intracellular transport	GO:1902582	207	0.011
immune response regulating signaling pathway	GO:0002764	2	0.011
single organism biosynthetic process	GO:0044711	206	0.011
oxoacid metabolic process	GO:0043436	103	0.011
positive regulation of intracellular signal transduction	GO:1902533	116	0.011
positive regulation of developmental process	GO:0051094	143	0.010
eye antennal disc development	GO:0035214	60	0.010
inorganic ion transmembrane transport	GO:0098660	73	0.010
nephron tubule development	GO:0072080	3	0.010
response to oxygen containing compound	GO:1901700	200	0.010
secondary metabolic process	GO:0019748	75	0.010
negative regulation of nervous system development	GO:0051961	92	0.010
positive regulation of cellular component organization	GO:0051130	156	0.010
organelle localization	GO:0051640	148	0.010
mesenchymal cell development	GO:0014031	1	0.010
regulation of molecular function	GO:0065009	217	0.010
purine containing compound metabolic process	GO:0072521	155	0.010
regulation of cell development	GO:0060284	215	0.010
nephron epithelium development	GO:0072009	3	0.010
cellular response to lipopolysaccharide	GO:0071222	3	0.010
negative regulation of rna biosynthetic process	GO:1902679	240	0.010
aromatic compound catabolic process	GO:0019439	166	0.010
golgi organization	GO:0007030	66	0.010
cilium assembly	GO:0042384	38	0.010
ribonucleotide metabolic process	GO:0009259	145	0.010
epiboly involved in wound healing	GO:0090505	2	0.010
organelle fission	GO:0048285	340	0.010
stem cell development	GO:0048864	79	0.010
maintenance of location	GO:0051235	73	0.010
notch signaling pathway	GO:0007219	120	0.010
cellular response to biotic stimulus	GO:0071216	4	0.010
nephron tubule morphogenesis	GO:0072078	3	0.010
endodermal cell differentiation	GO:0035987	3	0.010
intracellular mrna localization	GO:0008298	66	0.010
branching involved in open tracheal system development	GO:0060446	45	0.010
cytoskeleton dependent intracellular transport	GO:0030705	44	0.010
nucleoside metabolic process	GO:0009116	127	0.010

Gr21a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.028
urinary system disease	DOID:18	0.016
renal tubular transport disease	DOID:447	0.016
kidney disease	DOID:557	0.016
disease of metabolism	DOID:0014667	0.015
respiratory system disease	DOID:1579	0.013
lower respiratory tract disease	DOID:0050161	0.011
bronchial disease	DOID:1176	0.011
nervous system disease	DOID:863	0.011
disease of cellular proliferation	DOID:14566	0.011
acquired metabolic disease	DOID:0060158	0.010

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