Drosophila melanogaster

0 known processes

mthl8 (Dmel_CG32475)

methuselah-like 8

(Aliases: CG13406,CG11869,Mth-8,CG32475,anon-WO0170980.146,anon-WO0170980.145,Dmel\CG32475)

mthl8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
appendage developmentGO:00487364010.053
Fly
organonitrogen compound metabolic processGO:19015643180.049
vesicle mediated transportGO:00161923810.048
small molecule metabolic processGO:00442813050.045
imaginal disc derived appendage morphogenesisGO:00351143950.045
Fly
imaginal disc derived wing morphogenesisGO:00074763370.042
Fly
intracellular signal transductionGO:00355563000.042
imaginal disc derived appendage developmentGO:00487373990.042
Fly
appendage morphogenesisGO:00351073970.041
Fly
establishment of localization in cellGO:00516494020.041
catabolic processGO:00090564090.040
organic substance catabolic processGO:19015753080.038
eye morphogenesisGO:00485922600.037
regionalizationGO:00030024160.035
defense responseGO:00069523000.034
cellular catabolic processGO:00442483720.034
post embryonic appendage morphogenesisGO:00351203850.034
Fly
wing disc morphogenesisGO:00074723440.034
Fly
photoreceptor cell differentiationGO:00465301700.034
protein modification processGO:00362114380.033
positive regulation of response to stimulusGO:00485843230.033
negative regulation of signalingGO:00230572190.033
deathGO:00162652840.032
forebrain developmentGO:003090020.032
negative regulation of response to stimulusGO:00485852580.032
response to organic substanceGO:00100332840.031
oxoacid metabolic processGO:00434361030.031
cellular amino acid metabolic processGO:0006520610.031
regulation of multicellular organismal developmentGO:20000264140.031
phagocytosisGO:00069092150.031
carboxylic acid metabolic processGO:0019752920.030
regulation of epithelial cell proliferationGO:005067840.030
eye developmentGO:00016543230.030
localization of cellGO:00516742570.030
response to organophosphorusGO:004668320.030
anion homeostasisGO:005508130.030
negative regulation of cellular metabolic processGO:00313243820.030
regulation of cell cycleGO:00517262910.029
cell motilityGO:00488702510.029
cell proliferationGO:00082832990.028
immune system processGO:00023763470.028
regulation of localizationGO:00328792750.028
enzyme linked receptor protein signaling pathwayGO:00071671790.028
sensory organ morphogenesisGO:00905962600.028
response to monosaccharideGO:003428440.028
camera type eye developmentGO:004301040.028
sensory perception of chemical stimulusGO:00076061160.028
compound eye morphogenesisGO:00017452490.028
organic acid metabolic processGO:00060821030.028
endocytosisGO:00068973100.027
positive regulation of signalingGO:00230562430.027
single organism behaviorGO:00447083910.027
cellular protein modification processGO:00064644380.027
negative regulation of signal transductionGO:00099682060.027
phosphorylationGO:00163102940.026
single organism biosynthetic processGO:00447112060.026
programmed cell deathGO:00125012570.026
proteolysisGO:00065081920.026
positive regulation of cell communicationGO:00106472500.026
epithelial cell developmentGO:00020642740.025
positive regulation of signal transductionGO:00099672230.025
response to lipopolysaccharideGO:003249640.025
single organism catabolic processGO:00447122280.025
sensory perception of smellGO:0007608800.025
intracellular transportGO:00469072280.025
response to glucoseGO:000974920.025
negative regulation of cell communicationGO:00106482230.025
taxisGO:00423303040.025
cellular amine metabolic processGO:0044106120.024
telencephalon developmentGO:002153720.024
nucleobase containing small molecule metabolic processGO:00550861740.024
epithelial cell differentiationGO:00308553220.024
regulation of cellular amino acid metabolic processGO:000652100.024
exocrine system developmentGO:00352721620.024
single organism intracellular transportGO:19025822070.024
response to other organismGO:00517072930.024
steroid catabolic processGO:000670610.024
regulation of cellular ketone metabolic processGO:001056530.024
cell deathGO:00082192790.024
positive regulation of cell motilityGO:200014730.023
sensory perceptionGO:00076001960.023
positive regulation of cell migrationGO:003033520.023
neurological system processGO:00508773580.023
positive regulation of cellular biosynthetic processGO:00313283160.023
salivary gland developmentGO:00074311620.023
xenobiotic catabolic processGO:004217810.023
regulation of cellular amine metabolic processGO:003323830.023
regulation of intracellular signal transductionGO:19025312360.022
cellular response to chemical stimulusGO:00708871990.022
cellular ketone metabolic processGO:0042180240.022
body morphogenesisGO:001017120.022
respiratory system developmentGO:00605412130.022
nuclear divisionGO:00002803320.022
organelle fissionGO:00482853400.022
hormone catabolic processGO:004244730.022
negative regulation of gene expressionGO:00106293870.022
connective tissue developmentGO:006144830.022
compound eye developmentGO:00487493070.021
organophosphate metabolic processGO:00196371950.021
dorsal ventral pattern formationGO:00099531330.021
positive regulation of gene expressionGO:00106282900.021
regulation of immune system processGO:00026821760.021
cell migrationGO:00164772380.021
eye photoreceptor cell differentiationGO:00017541450.021
regulation of response to stressGO:00801342000.021
apoptotic processGO:00069151590.021
regulation of phosphorus metabolic processGO:00511742100.021
cellular response to dna damage stimulusGO:00069742230.021
organic substance transportGO:00717022570.021
response to biotic stimulusGO:00096072940.021
regulation of transcription from rna polymerase ii promoterGO:00063573780.020
response to oxygen containing compoundGO:19017002000.020
transcription from rna polymerase ii promoterGO:00063663680.020
cellular nitrogen compound catabolic processGO:00442701650.020
response to abiotic stimulusGO:00096283410.020
positive regulation of biosynthetic processGO:00098913160.020
developmental growthGO:00485892800.020
macromolecule catabolic processGO:00090571610.020
positive regulation of nucleobase containing compound metabolic processGO:00459353320.020
gland developmentGO:00487321910.020
chemotaxisGO:00069352490.020
protein localizationGO:00081042840.020
developmental programmed cell deathGO:00106231380.020
response to external biotic stimulusGO:00432072930.019
carbohydrate derivative metabolic processGO:19011352170.019
open tracheal system developmentGO:00074242040.019
regulation of transportGO:00510491810.019
amine metabolic processGO:0009308120.019
salivary gland morphogenesisGO:00074351450.019
response to radiationGO:00093141550.019
regulation of catalytic activityGO:00507901850.019
immune responseGO:00069552460.019
gland morphogenesisGO:00226121450.019
cellular macromolecule localizationGO:00707272200.019
defense response to other organismGO:00985422250.019
regulation of mitotic cell cycleGO:00073461900.019
purine nucleotide metabolic processGO:00061631460.018
negative regulation of developmental processGO:00510932010.018
nucleoside phosphate metabolic processGO:00067531620.018
kidney developmentGO:000182230.018
muscle organ developmentGO:00075171270.018
chromosome organizationGO:00512763600.018
embryonic development via the syncytial blastodermGO:00017001480.018
morphogenesis of an epitheliumGO:00020092760.018
positive regulation of rna biosynthetic processGO:19026802660.018
macromolecular complex assemblyGO:00650032560.018
neuron projection guidanceGO:00974852410.018
response to hexoseGO:000974630.018
lateral inhibitionGO:00463312060.018
vitamin biosynthetic processGO:000911010.018
establishment of protein localizationGO:00451841630.018
purine containing compound metabolic processGO:00725211550.018
response to nitrogen compoundGO:1901698900.018
regulation of molecular functionGO:00650092170.018
homeostatic processGO:00425921990.018
cytoplasmic transportGO:00164821300.018
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.017
negative regulation of nitrogen compound metabolic processGO:00511722650.017
positive regulation of macromolecule metabolic processGO:00106044050.017
monocarboxylic acid transportGO:001571830.017
cell divisionGO:00513012480.017
heterocycle catabolic processGO:00467001660.017
ethanolamine containing compound metabolic processGO:004243940.017
defense response to bacteriumGO:00427421780.017
response to bacteriumGO:00096171980.017
negative regulation of multicellular organismal processGO:00512411420.017
purine ribonucleotide metabolic processGO:00091501450.017
organic cyclic compound catabolic processGO:19013611680.017
small gtpase mediated signal transductionGO:0007264880.017
positive regulation of macromolecule biosynthetic processGO:00105572830.017
lipid metabolic processGO:00066291210.017
g protein coupled receptor signaling pathwayGO:00071861360.017
regulation of protein metabolic processGO:00512462560.017
positive regulation of nitrogen compound metabolic processGO:00511733540.017
anatomical structure homeostasisGO:0060249970.017
nucleotide metabolic processGO:00091171610.017
actin filament based processGO:00300292200.017
Fly
negative regulation of macromolecule biosynthetic processGO:00105582700.017
columnar cuboidal epithelial cell developmentGO:00020662490.017
ovarian follicle cell developmentGO:00307072480.017
axon guidanceGO:00074112330.017
photoreceptor cell developmentGO:0042461960.017
embryonic pattern specificationGO:00098801740.016
cell cell signaling involved in cell fate commitmentGO:00451682100.016
regulation of phosphate metabolic processGO:00192202100.016
ras protein signal transductionGO:0007265880.016
central nervous system developmentGO:00074172010.016
nucleobase containing compound catabolic processGO:00346551650.016
positive regulation of rna metabolic processGO:00512542710.016
ribonucleotide metabolic processGO:00092591450.016
developmental maturationGO:00217001720.016
protein complex assemblyGO:00064612000.016
regulation of programmed cell deathGO:00430671520.016
hindbrain developmentGO:003090220.016
embryonic morphogenesisGO:00485982060.016
Fly
regulation of cellular protein metabolic processGO:00322682430.016
cholesterol homeostasisGO:004263230.016
fat soluble vitamin biosynthetic processGO:004236210.016
cellular response to organic substanceGO:00713101320.016
cellular component assembly involved in morphogenesisGO:00109271510.016
aromatic compound catabolic processGO:00194391660.016
ion transportGO:00068111450.016
protein phosphorylationGO:00064681690.016
regulation of cellular catabolic processGO:00313291570.015
regulation of catabolic processGO:00098941700.015
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.015
protein transportGO:00150311550.015
detection of stimulusGO:00516061560.015
regulation of cell proliferationGO:00421271630.015
vitamin metabolic processGO:000676620.015
head developmentGO:00603221350.015
regulation of phosphorylationGO:00423251470.015
organonitrogen compound catabolic processGO:19015651280.015
regulation of cell cycle processGO:00105641810.015
protein complex biogenesisGO:00702712010.015
regulation of mapk cascadeGO:0043408920.015
columnar cuboidal epithelial cell differentiationGO:00020652560.015
segmentationGO:00352822070.015
growthGO:00400073590.015
tissue deathGO:00162711020.015
cellular macromolecule catabolic processGO:00442651360.015
response to extracellular stimulusGO:00099911160.014
organelle assemblyGO:00709251980.014
medium chain fatty acid metabolic processGO:005179110.014
regulation of response to external stimulusGO:00321011150.014
cellular protein localizationGO:00346131600.014
signal transduction by phosphorylationGO:00230141070.014
mitotic nuclear divisionGO:00070672130.014
organonitrogen compound biosynthetic processGO:19015661170.014
male gamete generationGO:00482322010.014
regulation of developmental growthGO:00486381740.014
establishment or maintenance of cell polarityGO:00071631670.014
response to nutrient levelsGO:00316671140.014
detection of chemical stimulusGO:0009593930.014
tissue morphogenesisGO:00487292970.014
Fly
cellular response to ethanolGO:007136140.014
negative regulation of biosynthetic processGO:00098902770.014
spermatogenesisGO:00072832000.014
eye photoreceptor cell developmentGO:0042462810.014
androgen metabolic processGO:000820910.014
response to painGO:004826530.014
negative regulation of epithelial cell proliferationGO:005068040.014
axonogenesisGO:00074092900.014
single organism cellular localizationGO:19025801800.014
organelle localizationGO:00516401480.014
regulation of nervous system developmentGO:00519602480.014
regulation of apoptotic processGO:00429811300.014
regulation of cell deathGO:00109411730.014
regulation of lipid transportGO:003236830.014
regulation of cell differentiationGO:00455953020.014
positive regulation of phosphorus metabolic processGO:00105621390.014
positive regulation of phosphate metabolic processGO:00459371390.014
chromosome segregationGO:00070591570.013
cellularizationGO:0007349900.013
positive regulation of catabolic processGO:00098961050.013
mapk cascadeGO:00001651070.013
positive regulation of multicellular organismal processGO:00512401430.013
autophagic cell deathGO:0048102830.013
blastoderm segmentationGO:00073501590.013
protein modification by small protein conjugation or removalGO:00706471060.013
axis specificationGO:00097981670.013
synaptic transmissionGO:00072682880.013
adult behaviorGO:00305341370.013
positive regulation of intracellular signal transductionGO:19025331160.013
negative regulation of protein metabolic processGO:0051248850.013
notch signaling pathwayGO:00072191200.013
purine nucleoside metabolic processGO:00422781270.013
compound eye photoreceptor cell differentiationGO:00017511400.013
defense response to gram negative bacteriumGO:0050829940.013
gene silencingGO:00164581380.013
fat soluble vitamin metabolic processGO:000677510.013
negative regulation of nucleic acid templated transcriptionGO:19035072400.013
polyol biosynthetic processGO:004617330.013
ribose phosphate metabolic processGO:00196931450.013
negative regulation of cellular biosynthetic processGO:00313272770.013
innate immune responseGO:00450871440.013
transmembrane transportGO:00550851390.013
ribonucleoside catabolic processGO:00424541120.013
cation transportGO:00068121100.013
regulation of notch signaling pathwayGO:00085931000.013
salivary gland cell autophagic cell deathGO:0035071830.013
cell cycle checkpointGO:0000075950.013
benzene containing compound metabolic processGO:004253730.013
wing disc pattern formationGO:0035222660.013
spindle organizationGO:00070512530.013
histolysisGO:00075591020.013
nucleoside metabolic processGO:00091161270.013
mesenchymal cell differentiationGO:004876210.013
positive regulation of nucleic acid templated transcriptionGO:19035082660.013
negative regulation of cell cycleGO:00457861160.013
camera type eye morphogenesisGO:004859320.012
posttranscriptional regulation of gene expressionGO:00106081450.012
protein catabolic processGO:00301631010.012
positive regulation of apoptotic signaling pathwayGO:200123540.012
imaginal disc pattern formationGO:0007447910.012
retina development in camera type eyeGO:006004140.012
multicellular organismal reproductive behaviorGO:00330571100.012
response to endogenous stimulusGO:00097191190.012
positive regulation of molecular functionGO:00440931360.012
salivary gland histolysisGO:0035070880.012
locomotory behaviorGO:00076261760.012
cell projection assemblyGO:0030031940.012
multi multicellular organism processGO:00447061230.012
regulation of organelle organizationGO:00330431960.012
regulation of cellular localizationGO:00603411360.012
negative regulation of nucleobase containing compound metabolic processGO:00459342610.012
synapse organizationGO:00508081960.012
immune response regulating signaling pathwayGO:000276420.012
muscle structure developmentGO:00610612240.012
wnt signaling pathwayGO:0016055980.012
response to organonitrogen compoundGO:0010243750.012
positive regulation of catalytic activityGO:00430851180.012
intracellular protein transportGO:00068861040.012
immune response activating signal transductionGO:000275720.012
axon developmentGO:00615642970.012
cellular lipid metabolic processGO:0044255830.012
regulation of anatomical structure morphogenesisGO:00226032420.012
regulation of mitotic cell cycle phase transitionGO:19019901300.012
positive regulation of developmental processGO:00510941430.012
mitotic cell cycle phase transitionGO:00447721380.012
muscle attachmentGO:0016203360.012
carbohydrate derivative catabolic processGO:19011361180.012
regulation of purine nucleotide metabolic processGO:1900542620.012
regulation of anatomical structure sizeGO:00900661630.012
meiotic cell cycleGO:00513211710.012
negative regulation of rna metabolic processGO:00512532510.012
maintenance of locationGO:0051235730.012
sensory perception of painGO:001923340.012
actin cytoskeleton organizationGO:00300362060.012
regulation of i kappab kinase nf kappab signalingGO:004312220.012
toxin catabolic processGO:000940710.012
rna processingGO:00063961470.012
acylglycerol biosynthetic processGO:004646320.012
sterol homeostasisGO:005509240.012
multi organism behaviorGO:00517051750.011
cholesterol transportGO:003030120.011
estrogen metabolic processGO:000821010.011
negative regulation of cellular protein metabolic processGO:0032269850.011
mrna metabolic processGO:00160711240.011
positive regulation of transcription dna templatedGO:00458932660.011
ribonucleoside metabolic processGO:00091191270.011
response to starvationGO:0042594970.011
nitrogen compound transportGO:0071705850.011
regulation of cell substrate adhesionGO:001081020.011
regulation of ras protein signal transductionGO:0046578930.011
neuron recognitionGO:00080381010.011
positive regulation of cellular catabolic processGO:0031331950.011
cellular homeostasisGO:0019725800.011
positive regulation of cellular amine metabolic processGO:003324000.011
regulation of immune responseGO:00507761180.011
negative regulation of cell deathGO:0060548810.011
epithelium migrationGO:00901321480.011
regulation of hydrolase activityGO:0051336970.011
cellular response to molecule of bacterial originGO:007121930.011
limb developmentGO:006017310.011
response to alcoholGO:0097305950.011
cell recognitionGO:00080371020.011
nucleoside phosphate catabolic processGO:19012921100.011
cellular response to oxygen containing compoundGO:1901701790.011
secondary metabolic processGO:0019748750.011
regulation of multi organism processGO:00439001310.011
regulation of cell cycle phase transitionGO:19019871300.011
ameboidal type cell migrationGO:00016671510.011
purine ribonucleoside metabolic processGO:00461281270.011
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.011
response to woundingGO:0009611940.011
positive regulation of reactive oxygen species metabolic processGO:200037900.011
neutral lipid biosynthetic processGO:004646020.011
spinal cord developmentGO:002151010.011
regulation of cellular component biogenesisGO:00440872010.011
translationGO:0006412690.011
membrane organizationGO:00610241120.011
rhythmic processGO:00485111060.011
mitotic spindle organizationGO:00070522200.011
response to copper ionGO:004668840.011
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.011
establishment of organelle localizationGO:00516561220.011
neurotransmitter metabolic processGO:004213320.011
positive regulation of cellular amino acid metabolic processGO:004576400.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092380.011
nucleoside triphosphate catabolic processGO:00091431080.010
anterior posterior pattern specificationGO:00099521360.010
negative regulation of intracellular signal transductionGO:1902532570.010
synaptic growth at neuromuscular junctionGO:00511241190.010
rna localizationGO:00064031150.010
regulation of cellular response to stressGO:0080135890.010
nucleotide catabolic processGO:00091661090.010
ribonucleoside triphosphate metabolic processGO:00091991190.010
negative regulation of rna biosynthetic processGO:19026792400.010
nephron developmentGO:007200630.010
regulation of epithelial cell differentiationGO:003085640.010
negative regulation of immune system processGO:0002683500.010
regulation of growthGO:00400082330.010
cellular response to lipopolysaccharideGO:007122230.010
peptidyl amino acid modificationGO:00181931050.010
oocyte developmentGO:00485991240.010
ion transmembrane transportGO:00342201220.010
cellular response to biotic stimulusGO:007121640.010
purine ribonucleoside catabolic processGO:00461301120.010
brain developmentGO:00074201200.010
detection of chemical stimulus involved in sensory perceptionGO:0050907750.010
regulation of small gtpase mediated signal transductionGO:0051056930.010
triglyceride biosynthetic processGO:001943220.010
endodermal cell differentiationGO:003598730.010
skin developmentGO:0043588650.010
regulation of proteolysisGO:0030162870.010
regulation of cell developmentGO:00602842150.010
acetate ester metabolic processGO:190061920.010
neuromuscular junction developmentGO:00075281490.010
matingGO:00076181200.010
nucleoside catabolic processGO:00091641120.010
extrinsic apoptotic signaling pathwayGO:009719110.010
dna metabolic processGO:00062592270.010
purine containing compound catabolic processGO:00725231120.010
pigmentationGO:0043473750.010
cellular response to endogenous stimulusGO:0071495800.010
ribonucleotide catabolic processGO:00092611090.010
negative regulation of cell cycle processGO:00109481090.010
cell cycle arrestGO:000705040.010

mthl8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.036
disease of metabolismDOID:001466700.018
cardiovascular system diseaseDOID:128700.018
nervous system diseaseDOID:86300.017
vascular diseaseDOID:17800.016
artery diseaseDOID:005082800.016
inherited metabolic disorderDOID:65500.013
hypertensionDOID:1076300.012
essential hypertensionDOID:1082500.012
disease of cellular proliferationDOID:1456600.012
cancerDOID:16200.012
organ system cancerDOID:005068600.011
central nervous system diseaseDOID:33100.011
diabetes mellitusDOID:935100.011
carbohydrate metabolism diseaseDOID:005001300.011
acquired metabolic diseaseDOID:006015800.011
glucose metabolism diseaseDOID:419400.011
musculoskeletal system diseaseDOID:1700.010
sensory system diseaseDOID:005015500.010